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Molecular and Cellular Biology Volume 18, 1998 - Issue 1
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DNA Dynamics and Chromosome Structure

Footprint Analysis of the RAG Protein Recombination Signal Sequence Complex for V(D)J Type Recombination

Fumikiyo Nagawaa Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo113
,
Kei-ichiro Ishiguroa Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo113
,
Akio Tsuboia Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo113
,
Tomoyuki Yoshidaa Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo113
,
Akiko Ishikawaa Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo113
,
Toshitada Takemorib Department of Immunology, National Institute of Infectious Diseases, Tokyo162, Japan
,
Anthony J. Otsukac Department of Biological Sciences, Illinois State University, Normal, Illinois61790-4120
&
Hitoshi Sakanoa Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Tokyo113Correspondence[email protected]
 show all
Pages 655-663 | Received 20 Aug 1997, Accepted 06 Oct 1997, Published online: 28 Mar 2023

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Pallabi De, Mandy M. Peak & Karla K. Rodgers. (2004) DNA Cleavage Activity of the V(D)J Recombination Protein RAG1 Is Autoregulated. Molecular and Cellular Biology 24:15, pages 6850-6860.
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Tadashi Nishihara, Fumikiyo Nagawa, Hirofumi Nishizumi, Masami Kodama, Satoshi Hirose, Reiko Hayashi & Hitoshi Sakano. (2004) In Vitro Processing of the 3′-Overhanging DNA in the Postcleavage Complex Involved in V(D)J Joining. Molecular and Cellular Biology 24:9, pages 3692-3702.
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Fumikiyo Nagawa, Masami Kodama, Tadashi Nishihara, Kei-ichiro Ishiguro & Hitoshi Sakano. (2002) Footprint Analysis of Recombination Signal Sequences in the 12/23 Synaptic Complex of V(D)J Recombination. Molecular and Cellular Biology 22:20, pages 7217-7225.
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Leslie E. Huye, Mary M. Purugganan, Ming-Ming Jiang & David B. Roth. (2002) Mutational Analysis of All Conserved Basic Amino Acids in RAG-1 Reveals Catalytic, Step Arrest, and Joining-Deficient Mutants in the V(D)J Recombinase. Molecular and Cellular Biology 22:10, pages 3460-3473.
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Patrick C. Swanson. (2002) Fine Structure and Activity of Discrete RAG-HMG Complexes on V(D)J Recombination Signals. Molecular and Cellular Biology 22:5, pages 1340-1351.
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Cynthia L. Mundy, Nadja Patenge, Adam G. W. Matthews & Marjorie A. Oettinger. (2002) Assembly of the RAG1/RAG2 Synaptic Complex. Molecular and Cellular Biology 22:1, pages 69-77.
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Carlos A. Gomez, Leon M. Ptaszek, Anna Villa, Fabio Bozzi, Cristina Sobacchi, Edward G. Brooks, Luigi D. Notarangelo, Eugenia Spanopoulou, Z. Q. Pan, Paolo Vezzoni, Patricia Cortes & Sandro Santagata. (2000) Mutations in Conserved Regions of the Predicted RAG2 Kelch Repeats Block Initiation of V(D)J Recombination and Result in Primary Immunodeficiencies. Molecular and Cellular Biology 20:15, pages 5653-5664.
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Vassilis Aidinis, Tiziana Bonaldi, Monica Beltrame, Sandro Santagata, Marco E. Bianchi & Eugenia Spanopoulou. (1999) The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2. Molecular and Cellular Biology 19:10, pages 6532-6542.
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Quinn M. Eastman, Isabelle J. Villey & David G. Schatz. (1999) Detection of RAG Protein-V(D)J Recombination Signal Interactions Near the Site of DNA Cleavage by UV Cross-Linking. Molecular and Cellular Biology 19:5, pages 3788-3797.
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Patrick C. Swanson & Stephen Desiderio. (1999) RAG-2 Promotes Heptamer Occupancy by RAG-1 in the Assembly of a V(D)J Initiation Complex. Molecular and Cellular Biology 19:5, pages 3674-3683.
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Yoshiko Akamatsu & Marjorie A. Oettinger. (1998) Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences. Molecular and Cellular Biology 18:8, pages 4670-4678.
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Lori M. Gwyn, Mandy M. Peak, Pallabi De, Negar S. Rahman & Karla K. Rodgers. (2009) A Zinc Site in the C-Terminal Domain of RAG1 Is Essential for DNA Cleavage Activity. Journal of Molecular Biology 390:5, pages 863-878.
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Fang Fang Yin, Scott Bailey, C Axel Innis, Mihai Ciubotaru, Satwik Kamtekar, Thomas A Steitz & David G Schatz. (2009) Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nature Structural & Molecular Biology 16:5, pages 499-508.
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Alfred Ian Lee, Sebastian D Fugmann, Lindsay G Cowell, Leon M Ptaszek, Garnett Kelsoe & David G Schatz. (2003) A Functional Analysis of the Spacer of V(D)J Recombination Signal Sequences. PLoS Biology 1:1, pages e1.
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