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Molecular and Cellular Biology Volume 18, 1998 - Issue 4
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Gene Expression

Synthetic Lethality of Yeast slt Mutations with U2 Small Nuclear RNA Mutations Suggests Functional Interactions between U2 and U5 snRNPs That Are Important for Both Steps of Pre-mRNA Splicing

Deming XuBanting and Best Department of Medical Research and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, CanadaM5G 1L6
,
Deborah J. FieldBanting and Best Department of Medical Research and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, CanadaM5G 1L6
,
Shou-Jiang TangBanting and Best Department of Medical Research and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, CanadaM5G 1L6
,
Arnaud MorisBanting and Best Department of Medical Research and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, CanadaM5G 1L6
,
Brian P. BobechkoBanting and Best Department of Medical Research and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, CanadaM5G 1L6
&
James D. FriesenBanting and Best Department of Medical Research and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, CanadaM5G 1L6Correspondence[email protected]
Pages 2055-2066 | Received 08 Sep 1997, Accepted 20 Jan 1998, Published online: 27 Mar 2023

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Clarisse van der Feltz & Aaron A. Hoskins. (2019) Structural and functional modularity of the U2 snRNP in pre-mRNA splicing. Critical Reviews in Biochemistry and Molecular Biology 54:5, pages 443-465.
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Shataparna Banerjee, Piyush Khandelia, Geetha Melangath, Samirul Bashir, Vijaykrishna Nagampalli & Usha Vijayraghavan. (2013) Splicing Functions and Global Dependency on Fission Yeast Slu7 Reveal Diversity in Spliceosome Assembly. Molecular and Cellular Biology 33:16, pages 3125-3136.
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Jennifer C. Hofmann, Alma Husedzinovic & Oliver J. Gruss. (2010) The function of spliceosome components in open mitosis . Nucleus 1:6, pages 447-459.
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Mikko J. Frilander & Xiaojuan Meng. (2005) Proximity of the U12 snRNA with both the 5′ Splice Site and the Branch Point during Early Stages of Spliceosome Assembly. Molecular and Cellular Biology 25:12, pages 4813-4825.
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Qiang Wang & Brian C. Rymond. (2003) Rds3p Is Required for Stable U2 snRNP Recruitment to the Splicing Apparatus. Molecular and Cellular Biology 23:20, pages 7339-7349.
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Michael Costanzo, Oliver Schub & Brenda Andrews. (2003) G1 Transcription Factors Are Differentially Regulated in Saccharomyces cerevisiae by the Swi6-Binding Protein Stb1. Molecular and Cellular Biology 23:14, pages 5064-5077.
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Deming Xu & James D. Friesen. (2001) Splicing Factor Slt11p and Its Involvement in Formation of U2/U6 Helix II in Activation of the Yeast Spliceosome. Molecular and Cellular Biology 21:4, pages 1011-1023.
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Puri Fortes, Joanna Kufel, Maarten Fornerod, Maria Polycarpou-Schwarz, Denis Lafontaine, David Tollervey & Iain W. Mattaj. (1999) Genetic and Physical Interactions Involving the Yeast Nuclear Cap-Binding Complex. Molecular and Cellular Biology 19:10, pages 6543-6553.
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Articles from other publishers (23)

Clarisse van der Feltz, Brandon Nikolai, Charles Schneider, Joshua C. Paulson, Xingyang Fu & Aaron A. Hoskins. (2021) Saccharomyces cerevisiae Ecm2 modulates the catalytic steps of pre-mRNA splicing . RNA 27:5, pages 591-603.
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Xiaofeng Zhang, Chuangye Yan, Jing Hang, Lorenzo I. Finci, Jianlin Lei & Yigong Shi. (2017) An Atomic Structure of the Human Spliceosome. Cell 169:5, pages 918-929.e14.
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Verity Nancollis, Jayalath P.D. Ruckshanthi, Lily Novak Frazer & Raymond T. O'Keefe. (2013) T he U5 sn RNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 sn RNP assembly . Journal of Cellular Biochemistry 114:12, pages 2770-2784.
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Hsin-Chou Chen & Soo-Chen Cheng. (2012) Functional roles of protein splicing factors. Bioscience Reports 32:4, pages 345-359.
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Brian C. Rymond. 2012. Alternative pre-mRNA Splicing. Alternative pre-mRNA Splicing 65 77 .
Aparna K. Sapra, Piyush Khandelia & Usha Vijayraghavan. (2008) The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis. Biochemical Journal 416:3, pages 365-374.
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Angela K. Hilliker, Melissa A. Mefford & Jonathan P. Staley. (2007) U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. Genes & Development 21:7, pages 821-834.
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Yosef Kaplan & Martin Kupiec. (2006) A role for the yeast cell cycle/splicing factor Cdc40 in the G1/S transition. Current Genetics 51:2, pages 123-140.
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P. Montaville, Y. Dai, C.Y. Cheung, K. Giller, S. Becker, M. Michalak, S.E. Webb, A.L. Miller & J. Krebs. (2006) Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1763:11, pages 1335-1343.
Crossref
Joanne C McGrail, Elaine M Tatum & Raymond T O'Keefe. (2006) Mutation in the U2 snRNA influences exon interactions of U5 snRNA loop 1 during pre-mRNA splicing. The EMBO Journal 25:16, pages 3813-3822.
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RICHARD J. GRAINGER & JEAN D. BEGGS. (2005) Prp8 protein: At the heart of the spliceosome. RNA 11:5, pages 533-557.
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Andreas N. Kuhn & Norbert F. Käufer. (2002) Pre-mRNA splicing in Schizosaccharomyces pombe. Current Genetics 42:5, pages 241-251.
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David A. Brow. (2002) Allosteric Cascade of Spliceosome Activation. Annual Review of Genetics 36:1, pages 333-360.
Crossref
Benigno C. Valdez, Laszlo Perlaky & Dale Henning. (2002) Expression, Cellular Localization, and Enzymatic Activities of RNA Helicase II/Guβ. Experimental Cell Research 276:2, pages 249-263.
Crossref
J. M. Sierra-Montes, A. V. Freund, L. M. Ruiz, M. N. Szmulewicz, D. J. Rowold & R. J. Herrera. (2002) Multiple forms of U2 snRNA coexist in the silk moth Bombyx mori . Insect Molecular Biology 11:1, pages 105-114.
Crossref
Scott W. Stevens, Daniel E. Ryan, Helen Y. Ge, Roger E. Moore, Mary K. Young, Terry D. Lee & John Abelson. (2002) Composition and Functional Characterization of the Yeast Spliceosomal Penta-snRNP. Molecular Cell 9:1, pages 31-44.
Crossref
Rob W van Nues & Jean D Beggs. (2001) Functional Contacts With a Range of Splicing Proteins Suggest a Central Role for Brr2p in the Dynamic Control of the Order of Events in Spliceosomes of Saccharomyces cerevisiae . Genetics 157:4, pages 1451-1467.
Crossref
Mikko J Frilander & Joan A Steitz. (2001) Dynamic Exchanges of RNA Interactions Leading to Catalytic Core Formation in the U12-Dependent Spliceosome. Molecular Cell 7:1, pages 217-226.
Crossref
Sigal Ben-Yehuda, Ian Dix, Caroline S Russell, Margaret McGarvey, Jean D Beggs & Martin Kupiec. (2000) Genetic and Physical Interactions Between Factors Involved in Both Cell Cycle Progression and Pre-mRNA Splicing in Saccharomyces cerevisiae . Genetics 156:4, pages 1503-1517.
Crossref
Sigal Ben-Yehuda, Caroline S Russell, Ian Dix, Jean D Beggs & Martin Kupiec. (2000) Extensive Genetic Interactions Between PRP8 and PRP17/CDC40, Two Yeast Genes Involved in Pre-mRNA Splicing and Cell Cycle Progression. Genetics 154:1, pages 61-71.
Crossref
Dong-Ho Kim, Gretchen Edwalds-Gilbert, Chengzhen Ren & Ren-Jang Lin. (1999) A Mutation in a Methionine tRNA Gene Suppresses the prp2-1 Ts Mutation and Causes a Pre-mRNA Splicing Defect in Saccharomyces cerevisiae. Genetics 153:3, pages 1105-1115.
Crossref
Scott W. Stevens & John Abelson. (1999) Purification of the yeast U4/U6⋅U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proceedings of the National Academy of Sciences 96:13, pages 7226-7231.
Crossref
Laura A. Lindsey & Mariano A. Garcia-Blanco. (1998) Functional Conservation of the Human Homolog of the Yeast Pre-mRNA Splicing Factor Prp17p. Journal of Biological Chemistry 273:49, pages 32771-32775.
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