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Molecular and Cellular Biology Volume 18, 1998 - Issue 4
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Cell Growth and Development

Sequence Divergence in the 3′ Untranslated Regions of Human ζ- and α-Globin mRNAs Mediates a Difference in Their Stabilities and Contributes to Efficient α-to-ζ Gene Developmental Switching

J. Eric Russellb Departments of Genetics;c Medicine (Hematology/Oncology), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104Correspondence[email protected]
,
Julia Moralesb Departments of Genetics;a Howard Hughes Medical Institute
,
Aleksandr V. Makeyevb Departments of Genetics;a Howard Hughes Medical Institute
&
Stephen A. Liebhaberb Departments of Genetics;c Medicine (Hematology/Oncology), University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania19104;a Howard Hughes Medical Institute
Pages 2173-2183 | Received 27 Oct 1997, Accepted 20 Jan 1998, Published online: 27 Mar 2023

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Yong Jiang, Xiang-Sheng Xu & J. Eric Russell. (2006) A Nucleolin-Binding 3′ Untranslated Region Element Stabilizes β-Globin mRNA In Vivo. Molecular and Cellular Biology 26:6, pages 2419-2429.
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Jia Yu & J. Eric Russell. (2001) Structural and Functional Analysis of an mRNP Complex That Mediates the High Stability of Human β-Globin mRNA. Molecular and Cellular Biology 21:17, pages 5879-5888.
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Alexander N. Chkheidze, Dmitry L. Lyakhov, Alexander V. Makeyev, Julia Morales, Jian Kong & Stephen A. Liebhaber. (1999) Assembly of the α-Globin mRNA Stability Complex Reflects Binary Interaction between the Pyrimidine-Rich 3′ Untranslated Region Determinant and Poly(C) Binding Protein αCP. Molecular and Cellular Biology 19:7, pages 4572-4581.
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Articles from other publishers (23)

Zhenning He, Decheng Song, Sebastiaan van Zalen & J Eric Russell. (2014) Structural determinants of human ζ-globin mRNA stability. Journal of Hematology & Oncology 7:1.
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Raman Manoharlal, Jyotsna Gorantala, Monika Sharma, Dominique Sanglard & Rajendra Prasad. (2010) PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans. Microbiology 156:2, pages 313-326.
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Tamara I Pestina, Phillip W Hargrove, Dennis Jay, John T Gray, Kelli M Boyd & Derek A Persons. (2009) Correction of Murine Sickle Cell Disease Using γ-Globin Lentiviral Vectors to Mediate High-level Expression of Fetal Hemoglobin. Molecular Therapy 17:2, pages 245-252.
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J. Eric Russell. (2007) A post-transcriptional process contributes to efficient γ-globin gene silencing in definitive erythroid cells. European Journal of Haematology 79:6, pages 516-525.
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Lois R. Manning, J. Eric Russell, Julio C. Padovan, Brian T. Chait, Anthony Popowicz, Robert S. Manning & James M. Manning. (2007) Human embryonic, fetal, and adult hemoglobins have different subunit interface strengths. Correlation with lifespan in the red cell. Protein Science 16:8, pages 1641-1658.
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Zhenning He & J. Eric Russell. (2006) Dynamic posttranscriptional regulation of ϵ-globin gene expression in vivo. Blood 109:2, pages 795-801.
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Bogdan DumitriuMichael R. PatrickJane P. PetschekSrujana CherukuriUrsula KlingmullerPaul L. FoxVéronique Lefebvre. (2006) Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood 108:4, pages 1198-1207.
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Yi Tang, Zhao Wang, Yue Huang, De-pei Liu, Guang Liu, Wei Shen, Xiaobin Tang, Dongxiao Feng & Chih-chuan Liang. (2005) Gene order in human α-globin locus is required for their temporal specific expressions. Genes to Cells 11:2, pages 123-131.
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Lyubomira ChakalovaCameron S. OsborneYan-Feng DaiBeatriz GoyenecheaAnna Metaxotou-MavromatiAntonios KattamisChristos KattamisPeter Fraser. (2005) The Corfu δβ thalassemia deletion disrupts γ-globin gene silencing and reveals post-transcriptional regulation of HbF expression. Blood 105:5, pages 2154-2160.
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David F Roe, Gale L Craviso & Jack C Waymire. (2004) Nicotinic stimulation modulates tyrosine hydroxylase mRNA half-life and protein binding to the 3′UTR in a manner that requires transcription. Molecular Brain Research 120:2, pages 91-102.
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Onur Bilenoglu, A. Nazli Basak & J. Eric Russell. (2002) A 3′UTR mutation affects β-globin expression without altering the stability of its fully processed mRNA. British Journal of Haematology 119:4, pages 1106-1114.
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Zhang Hua-bing, Liu De-Pei & Liang Chih-Chuan. (2002) The Control of Expression of the α-Globin Gene Cluster. International Journal of Hematology 76:5, pages 420-426.
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Raphael Lemaire, Jayendra Prasad, Tsuyoshi Kashima, Jennifer Gustafson, James L. Manley & Robert Lafyatis. (2002) Stability of a PKCI-1 -related mRNA is controlled by the splicing factor ASF/SF2: a novel function for SR proteins . Genes & Development 16:5, pages 594-607.
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Jean-Fran�ois Colas, Aaron Lawson & Gary C. Schoenwolf. (2000) Evidence that translation of smooth muscle alpha-actin mRNA is delayed in the chick promyocardium until fusion of the bilateral heart-forming regions. Developmental Dynamics 218:2, pages 316-330.
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J Elnatan, D Murphy, H-S Goh & D R Smith. (1999) HIT family genes: FHIT but not PKCI-1/HINT produces altered transcripts in colorectal cancer. British Journal of Cancer 81:5, pages 874-880.
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Rebecca D. Prokipcak, Afshin Raouf & Chunja Lee. (1999) The AU-Rich 3′ Untranslated Region of Human MDR1 mRNA Is an Inefficient mRNA Destabilizer. Biochemical and Biophysical Research Communications 261:3, pages 627-634.
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H.Y. LuoX.L. LiangC. FryeM. WonioG.D.V. HankinsD.H.K. ChuiB.P. Alter. (1999) Embryonic Hemoglobins Are Expressed in Definitive Cells. Blood 94:1, pages 359-361.
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Waltke R. Paulding & Maria F. Czyzyk-Krzeska. (1999) Regulation of Tyrosine Hydroxylase mRNA Stability by Protein-binding, Pyrimidine-rich Sequence in the 3′-Untranslated Region. Journal of Biological Chemistry 274:4, pages 2532-2538.
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J. Eric RussellStephen A. Liebhaber. (1998) Reversal of Lethal - and β-Thalassemias in Mice by Expression of Human Embryonic Globins. Blood 92:9, pages 3057-3063.
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J. Eric RussellStephen A. Liebhaber. (1998) Reversal of Lethal - and β-Thalassemias in Mice by Expression of Human Embryonic Globins. Blood 92:9, pages 3057-3063.
Crossref
J. ERIC RUSSELL, ALICE E. LEE & STEPHEN A. LIEBHABER. (1998) Full Developmental Silencing of the Embryonic zeta-Globin Gene Reflects Instability of its mRNA. Annals of the New York Academy of Sciences 850:1 COOLEY'S ANEM, pages 386-390.
Crossref
STEPHEN A. LIEBHABER & J. ERIC RUSSELL. (1998) Expression and Developmental Control of the Human alpha-Globin Gene Cluster. Annals of the New York Academy of Sciences 850:1 COOLEY'S ANEM, pages 54-63.
Crossref
Aparecida Maria Fontes, Jun-itsu Ito & Marcelo Jacobs-Lorena. 1998. 171 202 .

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