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Yaoxing Wu, Shouheng Jin, Qingxiang Liu, Yu Zhang, Ling Ma, Zhiyao Zhao, Shuai Yang, Yi-Ping Li & Jun Cui. (2021) Selective autophagy controls the stability of transcription factor IRF3 to balance type I interferon production and immune suppression. Autophagy 17:6, pages 1379-1392.
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Mehdi Moustaqil, Emma Ollivier, Hsin-Ping Chiu, Sarah Van Tol, Paulina Rudolffi-Soto, Christian Stevens, Akshay Bhumkar, Dominic J. B. Hunter, Alexander N. Freiberg, David Jacques, Benhur Lee, Emma Sierecki & Yann Gambin. (2021) SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species. Emerging Microbes & Infections 10:1, pages 178-195.
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Pradeep Bist, Susana Soo-Yeon Kim, Niyas Kudukil Pulloor, Kathleen McCaffrey, Sajith Kumar Nair, Yiliu Liu, Rongtuan Lin & Manoj N. Krishnan. (2017) ArfGAP Domain-Containing Protein 2 (ADAP2) Integrates Upstream and Downstream Modules of RIG-I Signaling and Facilitates Type I Interferon Production. Molecular and Cellular Biology 37:6.
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Kevin Looi, Niamh M. Troy, Luke W. Garratt, Thomas Iosifidis, Anthony Bosco, Alysia G. Buckley, Kak-Ming Ling, Kelly M. Martinovich, Elizabeth Kicic-Starcevich, Nicole C. Shaw, Erika N. Sutanto, Graeme R. Zosky, Paul J. Rigby, Alexander N. Larcombe, Darryl A. Knight, Anthony Kicic & Stephen M. Stick. (2016) Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Experimental Lung Research 42:7, pages 380-395.
Read now
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Soonhwa Song, Jae-Jin Lee, Hee-Jung Kim, Jeong Yoon Lee, Jun Chang & Kong-Joo Lee. (2016) Fas-Associated Factor 1 Negatively Regulates the Antiviral Immune Response by Inhibiting Translocation of Interferon Regulatory Factor 3 to the Nucleus. Molecular and Cellular Biology 36:7, pages 1136-1151.
Read now
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Pak-Yin Lui, Lok-Yin Roy Wong, Cheuk-Lai Fung, Kam-Leung Siu, Man-Lung Yeung, Kit-San Yuen, Chi-Ping Chan, Patrick Chiu-Yat Woo, Kwok-Yung Yuen & Dong-Yan Jin. (2016) Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3. Emerging Microbes & Infections 5:1, pages 1-9.
Read now
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Kashif Aziz Khan, Florence Dô, Alexandre Marineau, Priscilla Doyon, Jean-François Clément, James R. Woodgett, Bradley W. Doble & Marc J. Servant. (2015) Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway. Molecular and Cellular Biology 35:17, pages 3029-3043.
Read now
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Yixiang Chen, Jordan Wright, Xueqiong Meng & Keith N. Leppard. (2015) Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression. Molecular and Cellular Biology 35:10, pages 1660-1672.
Read now
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He-Xin Shi, Kai Yang, Xing Liu, Xin-Yi Liu, Bo Wei, Yu-Fei Shan, Lian-Hui Zhu & Chen Wang. (2010) Positive Regulation of Interferon Regulatory Factor 3 Activation by Herc5 via ISG15 Modification. Molecular and Cellular Biology 30:10, pages 2424-2436.
Read now
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Se-Jeong PARK, Mi-Young LEE, Bu-Soon SON & Hyung-Sun YOUN. (2009) TBK1-Targeted Suppression of TRIF-Dependent Signaling Pathway of Toll-Like Receptors by 6-Shogaol, an Active Component of Ginger. Bioscience, Biotechnology, and Biochemistry 73:7, pages 1474-1478.
Read now
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Pierre Génin, Rongtuan Lin, John Hiscott & Ahmet Civas. (2009) Differential Regulation of Human Interferon A Gene Expression by Interferon Regulatory Factors 3 and 7. Molecular and Cellular Biology 29:12, pages 3435-3450.
Read now
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Caleb M. Bailey, Daniel E. Abbott, Naira V. Margaryan, Zhila Khalkhali-Ellis & Mary J. C. Hendrix. (2008) Interferon Regulatory Factor 6 Promotes Cell Cycle Arrest and Is Regulated by the Proteasome in a Cell Cycle-Dependent Manner. Molecular and Cellular Biology 28:7, pages 2235-2243.
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Sergey V. Kozyrev & Marta E. Alarcon-Riquelme. (2007) The genetics and biology of Irf5-mediated signaling in lupus. Autoimmunity 40:8, pages 591-601.
Read now
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Houda Mokrani, Ossama Sharaf el dein, Zeyni Mansuroglu & Eliette Bonnefoy. (2006) Binding of YY1 to the Proximal Region of the Murine Beta Interferon Promoter Is Essential To Allow CBP Recruitment and K8H4/K14H3 Acetylation on the Promoter Region after Virus Infection. Molecular and Cellular Biology 26:22, pages 8551-8561.
Read now
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Goudong Hu & Betsy J Barnes. (2006) Interferon regulatory factor-5-regulated pathways as a target for colorectal cancer therapeutics. Expert Review of Anticancer Therapy 6:5, pages 775-784.
Read now
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John Hiscott & Rongtuan Lin. (2006) Inhibition of the interferon antiviral response by hepatitis C virus. Expert Review of Clinical Immunology 2:1, pages 49-58.
Read now
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Christopher A Baker, Zhi Yun Lu & Laura Manuelidis. (2004) Early induction of interferon-responsive mRNAs in Creutzfeldt-Jakob disease. Journal of Neurovirology 10:1, pages 29-40.
Read now
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Betsy J. Barnes, Merrill J. Kellum, Ann E. Field & Paula M. Pitha. (2002) Multiple Regulatory Domains of IRF-5 Control Activation, Cellular Localization, and Induction of Chemokines That Mediate Recruitment of T Lymphocytes. Molecular and Cellular Biology 22:16, pages 5721-5740.
Read now
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CHRISTOPHER F. BASLER & ADOLFO GARCÍA-SASTRE. (2002) VIRUSES AND THE TYPE I INTERFERON ANTIVIRAL SYSTEM: INDUCTION AND EVASION. International Reviews of Immunology 21:4-5, pages 305-337.
Read now
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Alla Y. Karpova, Lucienne V. Ronco & Peter M. Howley. (2001) Functional Characterization of Interferon Regulatory Factor 3a (IRF-3a), an Alternative Splice Isoform of IRF-3. Molecular and Cellular Biology 21:13, pages 4169-4176.
Read now
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Isabelle Marié, Eric Smith, Arun Prakash & David E. Levy. (2000) Phosphorylation-Induced Dimerization of Interferon Regulatory Factor 7 Unmasks DNA Binding and a Bipartite Transactivation Domain. Molecular and Cellular Biology 20:23, pages 8803-8814.
Read now
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Rongtuan Lin, Pierre Génin, Yaël Mamane & John Hiscott. (2000) Selective DNA Binding and Association with the CREB Binding Protein Coactivator Contribute to Differential Activation of Alpha/Beta Interferon Genes by Interferon Regulatory Factors 3 and 7. Molecular and Cellular Biology 20:17, pages 6342-6353.
Read now
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James V. Falvo, Bhavin S. Parekh, Charles H. Lin, Ernest Fraenkel & Tom Maniatis. (2000) Assembly of a Functional Beta Interferon Enhanceosome Is Dependent on ATF-2–c-jun Heterodimer Orientation. Molecular and Cellular Biology 20:13, pages 4814-4825.
Read now
Read now
K. Prasanna Kumar, Kevin M. McBride, Brian K. Weaver, Colin Dingwall & Nancy C. Reich. (2000) Regulated Nuclear-Cytoplasmic Localization of Interferon Regulatory Factor 3, a Subunit of Double-Stranded RNA-Activated Factor 1. Molecular and Cellular Biology 20:11, pages 4159-4168.
Read now
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James V. Falvo, Adele M. Uglialoro, Brigitta M. N. Brinkman, Menie Merika, Bhavin S. Parekh, Eunice Y. Tsai, Hadley C. King, Anthony D. Morielli, Ernest G. Peralta, Tom Maniatis, Dimitris Thanos & Anne E. Goldfeld. (2000) Stimulus-Specific Assembly of Enhancer Complexes on the Tumor Necrosis Factor Alpha Gene Promoter. Molecular and Cellular Biology 20:6, pages 2239-2247.
Read now
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Eliette Bonnefoy, Marie-Thérèse Bandu & Janine Doly. (1999) Specific Binding of High-Mobility-Group I (HMGI) Protein and Histone H1 to the Upstream AT-Rich Region of the Murine Beta Interferon Promoter: HMGI Protein Acts as a Potential Antirepressor of the Promoter. Molecular and Cellular Biology 19:4, pages 2803-2816.
Read now
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Rongtuan Lin, Yael Mamane & John Hiscott. (1999) Structural and Functional Analysis of Interferon Regulatory Factor 3: Localization of the Transactivation and Autoinhibitory Domains. Molecular and Cellular Biology 19:4, pages 2465-2474.
Read now
Read now
Atsuko Masumi, I-Ming Wang, Bruno Lefebvre, Xing-Jiao Yang, Yoshihiro Nakatani & Keiko Ozato. (1999) The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness. Molecular and Cellular Biology 19:3, pages 1810-1820.
Read now
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Rongtuan Lin, Christophe Heylbroeck, Pierre Genin, Paula M. Pitha & John Hiscott. (1999) Essential Role of Interferon Regulatory Factor 3 in Direct Activation of RANTES Chemokine Transcription. Molecular and Cellular Biology 19:2, pages 959-966.
Read now
Read now
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
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Xiangbin You, Ying Lei, Ping Zhang, Dequan Xu, Zulfiqar Ahmed & Youbing Yang. (2022) Role of transcription factors in porcine reproductive and respiratory syndrome virus infection: A review. Frontiers in Microbiology 13.
Crossref
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Crossref
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Crossref
Crossref
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Crossref
Crossref
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Crossref
Crossref
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Crossref
Crossref
Fangzhao Chen, Liurong Chen, Yinyan Li, Huiting Sang, Chunyu Zhang, Shuofeng Yuan & Jie Yang. (2022) TRAF3 Positively Regulates Host Innate Immune Resistance to Influenza A Virus Infection. Frontiers in Cellular and Infection Microbiology 12.
Crossref
Crossref
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Crossref
Crossref
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Crossref
Crossref
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Crossref
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Crossref
Crossref
Yao Fan, Xiang Li, Lei Zhang, Zhi Zong, Fangwei Wang, Jun Huang, Linghui Zeng, Chong Zhang, Haiyan Yan, Long Zhang & Fangfang Zhou. (2022) SUMOylation in Viral Replication and Antiviral Defense. Advanced Science 9:7, pages 2104126.
Crossref
Crossref
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Crossref
Crossref
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Crossref
Crossref
Katharine E. Magor. (2022) Evolution of RNA sensing receptors in birds. Immunogenetics 74:1, pages 149-165.
Crossref
Crossref
Marissa C. Locke, Lindsey E. Fox, Bria F. Dunlap, Alissa R. Young, Kristen Monte & Deborah J. Lenschow. (2022) Interferon Alpha, but Not Interferon Beta, Acts Early To Control Chronic Chikungunya Virus Pathogenesis. Journal of Virology 96:1.
Crossref
Crossref
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Crossref
Crossref
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Crossref
Crossref
Shujuan Xu, Jingying Xie, Xiangbo Zhang, Lei Chen, Yingjie Bi, Xiangrong Li, Adi Idris & Ruofei Feng. (2022) DDX56 antagonizes IFN-β production to enhance EMCV replication by inhibiting IRF3 nuclear translocation. Veterinary Microbiology 264, pages 109304.
Crossref
Crossref
Tian-Sheng He, Jingping Huang, Tian Chen, Zhi Zhang, Kuntai Cai, Jingge Yu & Liang-Guo Xu. (2021) The Kinase MAP4K1 Inhibits Cytosolic RNA-Induced Antiviral Signaling by Promoting Proteasomal Degradation of TBK1/IKKε. Microbiology Spectrum 9:3.
Crossref
Crossref
Kavya Srinivasan, Ashutosh Kumar Pandey, Ashlena Livingston & Sundararajan Venkatesh. (2021) Roles of host mitochondria in the development of COVID-19 pathology: Could mitochondria be a potential therapeutic target?. Molecular Biomedicine 2:1.
Crossref
Crossref
Valérie Lannoy, Anthony Côté-Biron, Claude Asselin & Nathalie Rivard. (2021) Phosphatases in toll-like receptors signaling: the unfairly-forgotten. Cell Communication and Signaling 19:1.
Crossref
Crossref
Kiramage Chathuranga, Asela Weerawardhana, Niranjan Dodantenna & Jong-Soo Lee. (2021) Regulation of antiviral innate immune signaling and viral evasion following viral genome sensing. Experimental & Molecular Medicine 53:11, pages 1647-1668.
Crossref
Crossref
Junfang Xu, Pin Wang, Zemeng Li, Zhiqing Li, Dan Han, Mingyue Wen, Qihang Zhao, Lianfeng Zhang, Yuanwu Ma, Wei Liu, Minghong Jiang, Xuan Zhang & Xuetao Cao. (2021) IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation. Cell Reports 37:5, pages 109926.
Crossref
Crossref
Fei‐Fei Gao, Juan‐Hua Quan, In‐Wook Choi, Yeon‐Jae Lee, Seul‐Gi Jang, Jae‐Min Yuk, Young‐Ha Lee & Guang‐Ho Cha. (2021)
FAF1 downregulation by
Toxoplasma gondii
enables host IRF3 mobilization and promotes parasite growth
. Journal of Cellular and Molecular Medicine 25:19, pages 9460-9472.
Crossref
Crossref
Fansen Meng, Zhengyang Yu, Dan Zhang, Shasha Chen, Hongxin Guan, Ruyuan Zhou, Qirou Wu, Qian Zhang, Shengduo Liu, Mukesh Kumar Venkat Ramani, Bing Yang, Xiao-Qun Ba, Jing Zhang, Jun Huang, Xueli Bai, Jun Qin, Xin-Hua Feng, Songying Ouyang, Yan Jessie Zhang, Tingbo Liang & Pinglong Xu. (2021) Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity. Molecular Cell 81:20, pages 4147-4164.e7.
Crossref
Crossref
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Crossref
Crossref
Masyelly Rojas, Patricia Luz-Crawford, Ricardo Soto-Rifo, Sebastián Reyes-Cerpa & Daniela Toro-Ascuy. (2021) The Landscape of IFN/ISG Signaling in HIV-1-Infected Macrophages and Its Possible Role in the HIV-1 Latency. Cells 10:9, pages 2378.
Crossref
Crossref
Charles R. Dixon, Poonam Malik, Jose I. de las Heras, Natalia Saiz-Ros, Flavia de Lima Alves, Mark Tingey, Eleanor Gaunt, A. Christine Richardson, David A. Kelly, Martin W. Goldberg, Greg J. Towers, Weidong Yang, Juri Rappsilber, Paul Digard & Eric C. Schirmer. (2021) STING nuclear partners contribute to innate immune signaling responses. iScience 24:9, pages 103055.
Crossref
Crossref
Enrico Palermo, Daniele Di Carlo, Marco Sgarbanti & John Hiscott. (2021) Type I Interferons in COVID-19 Pathogenesis. Biology 10:9, pages 829.
Crossref
Crossref
Dan-Dan Chen, Jing-Yu Jiang, Long-Feng Lu, Can Zhang, Xiao-Yu Zhou, Zhuo-Cong Li, Yu Zhou & Shun Li. (2021) Zebrafish Uba1 Degrades IRF3 through K48-Linked Ubiquitination to Inhibit IFN Production. The Journal of Immunology 207:2, pages 512-522.
Crossref
Crossref
Ioannis Kienes, Sarah Bauer, Clarissa Gottschild, Nora Mirza, Jens Pfannstiel, Martina Schröder & Thomas A. Kufer. (2021) DDX3X Links NLRP11 to the Regulation of Type I Interferon Responses and NLRP3 Inflammasome Activation. Frontiers in Immunology 12.
Crossref
Crossref
Kamal U. Saikh. (2021) MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity. Immunologic Research 69:2, pages 117-128.
Crossref
Crossref
Wei Zhang, Qi Wang, Fan Yang, Zixiang Zhu, Yueyue Duan, Yang Yang, Weijun Cao, Keshan Zhang, Junwu Ma, Xiangtao Liu & Haixue Zheng. (2021) JMJD6 negatively regulates cytosolic RNA induced antiviral signaling by recruiting RNF5 to promote activated IRF3 K48 ubiquitination. PLOS Pathogens 17:3, pages e1009366.
Crossref
Crossref
Hai-Tao Wang & Sun Hur. (2021) Substrate recognition by TRIM and TRIM-like proteins in innate immunity. Seminars in Cell & Developmental Biology 111, pages 76-85.
Crossref
Crossref
Yonghong Yang, Cui Zhang, Dehuai Jing, Heng He, Xiaoyu Li, Yibo Wang, Yufen Qin, Xiao Xiao, Huabao Xiong & Guangxi Zhou. (2021) IRF5 Acts as a Potential Therapeutic Marker in Inflammatory Bowel Diseases. Inflammatory Bowel Diseases 27:3, pages 407-417.
Crossref
Crossref
Lauren S. VaughnEvelyn ChukwurahRekha C. Patel. (2021) Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling. Biochemical Journal 478:3, pages 493-510.
Crossref
Crossref
Samuel Hardy, Ben Jackson, Stephen Goodbourn & Julian Seago. (2021)
Classical Swine Fever Virus N
pro
Antagonizes IRF3 To Prevent Interferon-Independent TLR3- and RIG-I-Mediated Apoptosis
. Journal of Virology 95:5.
Crossref
Crossref
Ioannis Kienes, Tanja Weidl, Nora Mirza, Mathias Chamaillard & Thomas A. Kufer. (2021) Role of NLRs in the Regulation of Type I Interferon Signaling, Host Defense and Tolerance to Inflammation. International Journal of Molecular Sciences 22:3, pages 1301.
Crossref
Crossref
Giulia Gallo, Grégory Caignard, Karine Badonnel, Guillaume Chevreux, Samuel Terrier, Agnieszka Szemiel, Gleyder Roman-Sosa, Florian Binder, Quan Gu, Ana Da Silva Filipe, Rainer G. Ulrich, Alain Kohl, Damien Vitour, Noël Tordo & Myriam Ermonval. (2021) Interactions of Viral Proteins from Pathogenic and Low or Non-Pathogenic Orthohantaviruses with Human Type I Interferon Signaling. Viruses 13:1, pages 140.
Crossref
Crossref
Tushar Dhawan, Muhammad Atif Zahoor, Nishant Heryani, Samuel Tekeste Workenhe, Aisha Nazli & Charu Kaushic. (2021) TRIM26 Facilitates HSV-2 Infection by Downregulating Antiviral Responses through the IRF3 Pathway. Viruses 13:1, pages 70.
Crossref
Crossref
Lindsey E. Fox, Marissa C. Locke & Deborah J. Lenschow. (2020) Context Is Key: Delineating the Unique Functions of IFNα and IFNβ in Disease. Frontiers in Immunology 11.
Crossref
Crossref
David N. Hare, Kaushal Baid, Anna Dvorkin-Gheva & Karen L. Mossman. (2020) Virus-Intrinsic Differences and Heterogeneous IRF3 Activation Influence IFN-Independent Antiviral Protection. iScience 23:12, pages 101864.
Crossref
Crossref
Timothy R. Howard & Ileana M. Cristea. (2020) Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective. Biomolecules 10:12, pages 1591.
Crossref
Crossref
Louise Dalskov, Ryo Narita, Line L Andersen, Nanna Jensen, Sonia Assil, Kennith H Kristensen, Jacob G Mikkelsen, Takashi Fujita, Trine H Mogensen, Søren R Paludan & Rune Hartmann. (2020) Characterization of distinct molecular interactions responsible for IRF3 and IRF7 phosphorylation and subsequent dimerization. Nucleic Acids Research 48:20, pages 11421-11433.
Crossref
Crossref
Biswas Neupane, Dhiraj Acharya, Farzana Nazneen, Gabriel Gonzalez-Fernandez, Alex Sutton Flynt & Fengwei Bai. (2020) Interleukin-17A Facilitates Chikungunya Virus Infection by Inhibiting IFN-α2 Expression. Frontiers in Immunology 11.
Crossref
Crossref
Miao Tian, Xiumei Wang, Jihong Sun, Wenlong Lin, Lumin Chen, Shengduo Liu, Ximei Wu, Liyun Shi, Pinglong Xu, Xiujun Cai & Xiaojian Wang. (2020) IRF3 prevents colorectal tumorigenesis via inhibiting the nuclear translocation of β-catenin. Nature Communications 11:1.
Crossref
Crossref
Chai Foong Lai, Ting-Yu Wang, Min-I Yeh & Tzong-Yueh Chen. (2020) Characterization of orange-spotted grouper (Epinephelus coioides) interferon regulatory factor 4 regulated by heat shock factor 1 during heat stress in response to antiviral immunity. Fish & Shellfish Immunology 106, pages 755-767.
Crossref
Crossref
Kyung Ho KIM, Dong-Hee CHO, Min-Soo JOO, Kwang-Min CHOI, Chan-Il PARK & Mu-Chan KIM. (2020) Molecular Characterization and Expression Analysis of the Interferon Regulatory Factor 3 (IRF3) Gene from Red sea Bream Pagrus major. JOURNAL OF FISHRIES AND MARINE SCIENCES EDUCATION 32:5, pages 1153-1167.
Crossref
Crossref
Thomas M. Petro. (2020) IFN Regulatory Factor 3 in Health and Disease. The Journal of Immunology 205:8, pages 1981-1989.
Crossref
Crossref
Tao Jing, Baoyu Zhao, Pengbiao Xu, Xinsheng Gao, Lei Chi, Huajun Han, Banumathi Sankaran & Pingwei Li. (2020) The Structural Basis of IRF-3 Activation upon Phosphorylation. The Journal of Immunology 205:7, pages 1886-1896.
Crossref
Crossref
Timo Oosenbrug, Michel J. van de Graaff, Mariëlle C. Haks, Sander van Kasteren & Maaike E. Ressing. (2020) An alternative model for type I interferon induction downstream of human TLR2. Journal of Biological Chemistry 295:42, pages 14325-14342.
Crossref
Crossref
Geon-Woo Kim, Hasan Imam, Mohsin Khan & Aleem Siddiqui. (2020) N6-Methyladenosine modification of hepatitis B and C viral RNAs attenuates host innate immunity via RIG-I signaling. Journal of Biological Chemistry 295:37, pages 13123-13133.
Crossref
Crossref
Kamal U. Saikh, Elaine M. Morazzani, Ashley E. Piper, Russell R. Bakken & Pamela J. Glass. (2020) A small molecule inhibitor of MyD88 exhibits broad spectrum antiviral activity by up regulation of type I interferon. Antiviral Research 181, pages 104854.
Crossref
Crossref
Sofiya Tsimbalyuk, Emily Cross, Mikayla Hoad, Camilla Donnelly, Justin Roby & Jade Forwood. (2020) The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import. Cells 9:8, pages 1913.
Crossref
Crossref
Linda J. Visser, Chiara Aloise, Kirby N. Swatek, Gisselle N. Medina, Karin M. Olek, Huib H. Rabouw, Raoul J. de Groot, Martijn A. Langereis, Teresa de los Santos, David Komander, Tim Skern & Frank J. M. van Kuppeveld. (2020) Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression. PLOS Pathogens 16:7, pages e1008702.
Crossref
Crossref
Hella Schwanke, Markus Stempel & Melanie M. Brinkmann. (2020) Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression. Viruses 12:7, pages 733.
Crossref
Crossref
Michelle A. Kennedy, William A. Hofstadter & Ileana M. Cristea. (2020) TRANSPIRE: A Computational Pipeline to Elucidate Intracellular Protein Movements from Spatial Proteomics Data Sets. Journal of the American Society for Mass Spectrometry 31:7, pages 1422-1439.
Crossref
Crossref
Jorge Vera-Otarola, Loretto Solis, Fernando Lowy, Valeria Olguín, Jenniffer Angulo, Karla Pino, Nicole D. Tischler, Carola Otth, Paula Padula & Marcelo López-Lastra. (2020) The Andes Orthohantavirus NSs Protein Antagonizes the Type I Interferon Response by Inhibiting MAVS Signaling. Journal of Virology 94:13.
Crossref
Crossref
Pak-Hin Hinson Cheung, Tak-Wang Terence Lee, Chun Kew, Honglin Chen, Kwok-Yung Yuen, Chi-Ping Chan & Dong-Yan Jin. (2020) Virus subtype-specific suppression of MAVS aggregation and activation by PB1-F2 protein of influenza A (H7N9) virus. PLOS Pathogens 16:6, pages e1008611.
Crossref
Crossref
Shasha Li, Jinping Yang, Zixiang Zhu & Haixue Zheng. (2020) Porcine Epidemic Diarrhea Virus and the Host Innate Immune Response. Pathogens 9:5, pages 367.
Crossref
Crossref
Zeng Cai, Meng-Xin Zhang, Zhen Tang, Qiang Zhang, Jing Ye, Tian-Chen Xiong, Zhi-Dong Zhang & Bo Zhong. (2020) USP22 promotes IRF3 nuclear translocation and antiviral responses by deubiquitinating the importin protein KPNA2. Journal of Experimental Medicine 217:5.
Crossref
Crossref
Laura Marcos-Villar, Estanislao Nistal-Villan, Noelia Zamarreño, Urtzi Garaigorta, Pablo Gastaminza & Amelia Nieto. (2020) Interferon-β Stimulation Elicited by the Influenza Virus Is Regulated by the Histone Methylase Dot1L through the RIG-I-TRIM25 Signaling Axis. Cells 9:3, pages 732.
Crossref
Crossref
Dan Li, Shaozu Fu, Zhengqian Wu, Wenping Yang, Yi Ru, Hongbing Shu, Xiangtao Liu & Haixue Zheng. (2020) DDX56 inhibits type I interferon by disrupting assembly of IRF3–IPO5 to inhibit IRF3 nucleus import. Journal of Cell Science 133:5.
Crossref
Crossref
Lindsey E. Cook, Marissa C. Locke, Alissa R. Young, Kristen Monte, Matthew L. Hedberg, Raeann M. Shimak, Kathleen C. F. Sheehan, Deborah J. Veis, Michael S. Diamond & Deborah J. Lenschow. (2019) Distinct Roles of Interferon Alpha and Beta in Controlling Chikungunya Virus Replication and Modulating Neutrophil-Mediated Inflammation. Journal of Virology 94:1.
Crossref
Crossref
Jiunn‐Diann Lin, Shun‐Fa Yang, Yuan‐Hung Wang, Wen‐Fang Fang, Kam‐Tsun Tang & Chao‐Wen Cheng. (2019) Associations of gene polymorphisms in interferon‐alpha signature‐related genes with autoimmune thyroid diseases. Clinical Endocrinology 91:6, pages 860-868.
Crossref
Crossref
Marta L. DeDiego, Luis Martinez-Sobrido & David J. Topham. (2019) Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses. Journal of Virology 93:21.
Crossref
Crossref
Cha Yang, Xiaokun Liu, Tailang Cheng, Rong Xiao, Qingxia Gao, Fan Ming, Meilin Jin, Huanchun Chen & Hongbo Zhou. (2019) LYAR Suppresses Beta Interferon Induction by Targeting Phosphorylated Interferon Regulatory Factor 3. Journal of Virology 93:21.
Crossref
Crossref
Nicolas Tremblay, Wesley Freppel, Aïssatou Aïcha Sow & Laurent Chatel-Chaix. (2019) The Interplay between Dengue Virus and the Human Innate Immune System: A Game of Hide and Seek. Vaccines 7:4, pages 145.
Crossref
Crossref
Luke D. Jasenosky, Cristhian Cadena, Chad E. Mire, Viktoriya Borisevich, Viraga Haridas, Shahin Ranjbar, Aya Nambu, Sina Bavari, Veronica Soloveva, Supriya Sadukhan, Gail H. Cassell, Thomas W. Geisbert, Sun Hur & Anne E. Goldfeld. (2019) The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus. iScience 19, pages 1279-1290.
Crossref
Crossref
Xiaohong Du, Fang Meng, Di Peng, Zining Wang, Wei Ouyang, Yu Han, Yayun Gu, Lingbo Fan, Fei Wu, Xiaodong Jiang, Feng Xu & F. Xiao-Feng Qin. (2019) Noncanonical Role of FBXO6 in Regulating Antiviral Immunity. The Journal of Immunology 203:4, pages 1012-1020.
Crossref
Crossref
Timo Reisländer, Emilia Puig Lombardi, Florian J. Groelly, Ana Miar, Manuela Porru, Serena Di Vito, Benjamin Wright, Helen Lockstone, Annamaria Biroccio, Adrian Harris, Arturo Londoño-Vallejo & Madalena Tarsounas. (2019) BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors. Nature Communications 10:1.
Crossref
Crossref
Raquel García-Belmonte, Daniel Pérez-Núñez, Marco Pittau, Juergen A. Richt & Yolanda Revilla. (2019) African Swine Fever Virus Armenia/07 Virulent Strain Controls Interferon Beta Production through the cGAS-STING Pathway. Journal of Virology 93:12.
Crossref
Crossref
Matthew J. Simons, Elena E. Gorbunova & Erich R. Mackow. (2019) Unique Interferon Pathway Regulation by the Andes Virus Nucleocapsid Protein Is Conferred by Phosphorylation of Serine 386. Journal of Virology 93:10.
Crossref
Crossref
Baoyu Zhao, Fenglei Du, Pengbiao Xu, Chang Shu, Banumathi Sankaran, Samantha L. Bell, Mengmeng Liu, Yuanjiu Lei, Xinsheng Gao, Xiaofeng Fu, Fanxiu Zhu, Yang Liu, Arthur Laganowsky, Xueyun Zheng, Jun-Yuan Ji, A. Phillip West, Robert O. Watson & Pingwei Li. (2019) A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1. Nature 569:7758, pages 718-722.
Crossref
Crossref
Jae-Hoon Kim, Ji-Eun Yoon, Chamilani Nikapitiya, Tae-Hwan Kim, Md Bashir Uddin, Hyun-Cheol Lee, Yong-Hoon Kim, Jung Hwan Hwang, Kiramage Chathuranga, W.A. Gayan Chathuranga, Hueng-Sik Choi, Chul-Joong Kim, Jae U. Jung, Chul-Ho Lee & Jong-Soo Lee. (2019) Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus. Cell Reports 27:7, pages 2105-2118.e5.
Crossref
Crossref
Fengyan Luo, Hainan Liu, Shasha Yang, Yi Fang, Zhihu Zhao, Yong Hu, Yanwen Jin, Ping Li, Ting Gao, Cheng Cao & Xuan Liu. (2019) Nonreceptor Tyrosine Kinase c-Abl– and Arg-Mediated IRF3 Phosphorylation Regulates Innate Immune Responses by Promoting Type I IFN Production. The Journal of Immunology 202:8, pages 2254-2265.
Crossref
Crossref
Wanwan Huai, Xingguang Liu, Chunmei Wang, Yunkai Zhang, Xi Chen, Xiang Chen, Sheng Xu, Tim Thomas, Nan Li & Xuetao Cao. (2019) KAT8 selectively inhibits antiviral immunity by acetylating IRF3. Journal of Experimental Medicine 216:4, pages 772-785.
Crossref
Crossref
Susana Soo-Yeon Kim, Lynette Sze & Kong-Peng Lam. (2019) The stress granule protein G3BP1 binds viral dsRNA and RIG-I to enhance interferon-β response. Journal of Biological Chemistry 294:16, pages 6430-6438.
Crossref
Crossref
Niloufar Yousefi, Fattah Sotoodehnejadnematalahi, Nooshin Heshmati-Fakhr, Mohammad Sayyah, Masoud Hoseini, Soheil Ghassemi, Shayan Aliakbari & Hamid Gholami Pourbadie. (2019) Prestimulation of Microglia Through TLR4 Pathway Promotes Interferon Beta Expression in a Rat Model of Alzheimer’s Disease. Journal of Molecular Neuroscience 67:4, pages 495-503.
Crossref
Crossref
Markus Stempel, Baca Chan, Vanda Juranić Lisnić, Astrid Krmpotić, Josephine Hartung, Søren R Paludan, Nadia Füllbrunn, Niels AW Lemmermann & Melanie M Brinkmann. (2019)
The herpesviral antagonist m152 reveals differential activation of
STING
‐dependent
IRF
and
NF
‐κB signaling and
STING
's dual role during
MCMV
infection
. The EMBO Journal 38:5.
Crossref
Crossref
Tanmay Majumdar, Shagun Sharma, Manmohan Kumar, Md. Arafat Hussain, Namita Chauhan, Inderjeet Kalia, Amit Kumar Sahu, Vipin Singh Rana, Ruchi Bharti, Arun Kumar Haldar, Agam P. Singh & Shibnath Mazumder. (2019) Tryptophan-kynurenine pathway attenuates β-catenin-dependent pro-parasitic role of STING-TICAM2-IRF3-IDO1 signalosome in Toxoplasma gondii infection. Cell Death & Disease 10:3.
Crossref
Crossref
Ye Hong, Maosheng Bai, Xian Qi, Chuan Li, Mifang Liang, Dexin Li, Carol J. Cardona & Zheng Xing. (2019) Suppression of the IFN-α and -β Induction through Sequestering IRF7 into Viral Inclusion Bodies by Nonstructural Protein NSs in Severe Fever with Thrombocytopenia Syndrome Bunyavirus Infection. The Journal of Immunology 202:3, pages 841-856.
Crossref
Crossref
Florian Pfaff, Sara Hägglund, Martina Zoli, Sandra Blaise-Boisseau, Eve Laloy, Susanne Koethe, Daniela Zühlke, Katharina Riedel, Stephan Zientara, Labib Bakkali-Kassimi, Jean-François Valarcher, Dirk Höper, Martin Beer & Michael Eschbaumer. (2019) Proteogenomics Uncovers Critical Elements of Host Response in Bovine Soft Palate Epithelial Cells Following In Vitro Infection with Foot-And-Mouth Disease Virus. Viruses 11:1, pages 53.
Crossref
Crossref
Yuqiang Cheng, Minxiang Lun, Yunxia Liu, Hengan Wang, Yaxian Yan & Jianhe Sun. (2019) CRISPR/Cas9-Mediated Chicken TBK1 Gene Knockout and Its Essential Role in STING-Mediated IFN-β Induction in Chicken Cells. Frontiers in Immunology 9.
Crossref
Crossref
Ziyang Wang, Chunjie Sheng, Chen Yao, Hongyuan Chen, Dan Wang & Shuai Chen. (2019) The EF-Hand Protein CALML6 Suppresses Antiviral Innate Immunity by Impairing IRF3 Dimerization. Cell Reports 26:5, pages 1273-1285.e5.
Crossref
Crossref
Jennifer Deborah Wuerth, Matthias Habjan, Julia Wulle, Giulio Superti-Furga, Andreas Pichlmair & Friedemann Weber. (2018) NSs Protein of Sandfly Fever Sicilian Phlebovirus Counteracts Interferon (IFN) Induction by Masking the DNA-Binding Domain of IFN Regulatory Factor 3. Journal of Virology 92:23.
Crossref
Crossref
Ashwini Zolekar, Victor. J. T. Lin, Nigam M. Mishra, Yin Ying Ho, Hamed S. Hayatshahi, Abhishek Parab, Rohit Sampat, Xiaoyan Liao, Peter Hoffmann, Jin Liu, Kyle A. Emmitte & Yu-Chieh Wang. (2018) Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1. British Journal of Cancer 119:12, pages 1538-1551.
Crossref
Crossref
Huifang Lv, Wang Dong, Zhi Cao, Jihui Lin, Yueling Ouyang, Kangkang Guo, Cunfa Li & Yanming Zhang. (2018) Classical swine fever virus non-structural protein 4B binds tank-binding kinase 1. Journal of Biosciences 43:5, pages 947-957.
Crossref
Crossref
Eun-Jin Choi, Yuping Ren, Yu Chen, Shengxuan Liu, Wenzhe Wu, Junping Ren, Pingyuan Wang, Roberto P. Garofalo, Jia Zhou & Xiaoyong Bao. (2018) Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection. Journal of Virology 92:22.
Crossref
Crossref
Hideo Negishi, Tadatsugu Taniguchi & Hideyuki Yanai. (2018) The Interferon (IFN) Class of Cytokines and the IFN Regulatory Factor (IRF) Transcription Factor Family. Cold Spring Harbor Perspectives in Biology 10:11, pages a028423.
Crossref
Crossref
Yanna Xiao, Matthew B. Reeves, Adam F. Caulfield, Danyel Evseev & Katharine E. Magor. (2018) The core promoter controls basal and inducible expression of duck retinoic acid inducible gene-I (RIG-I). Molecular Immunology 103, pages 156-165.
Crossref
Crossref
Ah-Yeon Kim, Hyun-Jin Shim, Su Yeon Kim, Sunghye Heo & Hyung-Sun Youn. (2018) Differential regulation of MyD88- and TRIF-dependent signaling pathways of Toll-like receptors by cardamonin. International Immunopharmacology 64, pages 1-9.
Crossref
Crossref
Wanwan Zhang, Zelin Li, Peng Jia, Wei Liu, Meisheng Yi & Kuntong Jia. (2018) Interferon regulatory factor 3 from sea perch (Lateolabrax japonicus) exerts antiviral function against nervous necrosis virus infection. Developmental & Comparative Immunology 88, pages 200-205.
Crossref
Crossref
Jun Tsuyama, Akari Nakamura, Hiroaki Ooboshi, Akihiko Yoshimura & Takashi Shichita. (2018) Pivotal role of innate myeloid cells in cerebral post-ischemic sterile inflammation. Seminars in Immunopathology 40:6, pages 523-538.
Crossref
Crossref
Chengming Ding, Jun He, Jun Zhao, Junhua Li, Jie Chen, Wenyan Liao, Yi Zeng, Jing Zhong, Chaoying Wei, Liming Zhang, Mei Zhou, Zeming Jia, Yaoting Zhang, Hui Li, Yuzheng Zhou, Xiaolong Xiao, Dong Han, Chong Li, Zhu Zhu, Zanxian Xia & Jian Peng. (2018) β‐catenin regulates IRF3‐mediated innate immune signalling in colorectal cancer. Cell Proliferation 51:5.
Crossref
Crossref
Ribhav Mishra, Arun Upadhyay, Vijay Kumar Prajapati & Amit Mishra. (2018) Proteasome-mediated proteostasis: Novel medicinal and pharmacological strategies for diseases. Medicinal Research Reviews 38:6, pages 1916-1973.
Crossref
Crossref
Zifeng Zheng, Jieyu Yang, Xuan Jiang, Yalan Liu, Xiaowei Zhang, Mei Li, Mudan Zhang, Ming Fu, Kai Hu, Hanzhong Wang, Min-Hua Luo, Peng Gong & Qinxue Hu. (2018) Tick-Borne Encephalitis Virus Nonstructural Protein NS5 Induces RANTES Expression Dependent on the RNA-Dependent RNA Polymerase Activity. The Journal of Immunology 201:1, pages 53-68.
Crossref
Crossref
Shahrukh Husain, Vijay Kumar & Md. Imtaiyaz Hassan. (2018) Phosphorylation-induced changes in the energetic frustration in human Tank binding kinase 1. Journal of Theoretical Biology 449, pages 14-22.
Crossref
Crossref
Arran Hodgkinson, Gilles Uzé, Ovidiu Radulescu & Dumitru Trucu. (2018) Signal Propagation in Sensing and Reciprocating Cellular Systems with Spatial and Structural Heterogeneity. Bulletin of Mathematical Biology 80:7, pages 1900-1936.
Crossref
Crossref
Jeroen Witteveldt, Alasdair Ivens & Sara Macias. (2018) Inhibition of Microprocessor Function during the Activation of the Type I Interferon Response. Cell Reports 23:11, pages 3275-3285.
Crossref
Crossref
Hyeon-Myeong Shin, Hyun-Jin Shim, Ah-Yeon Kim, Yoo Jung Lee, Hyeonjeong Nam & Hyung-Sun Youn. (2018) Eicosapentaenoic acid suppresses TRIF-dependent signaling pathway of TLRs by targeting TBK1. Journal of Food Biochemistry 42:2, pages e12490.
Crossref
Crossref
Tomio Matsumura, Shigeaki Hida, Masato Kitazawa, Chifumi Fujii, Akira Kobayashi, Michiko Takeoka, Shun-ichiro Taniguchi & Shin-ichi Miyagawa. (2018) Fascin1 suppresses RIG-I–like receptor signaling and interferon-β production by associating with IκB kinase Ε (IKKΕ) in colon cancer. Journal of Biological Chemistry 293:17, pages 6326-6336.
Crossref
Crossref
Ah-Yeon Kim, Hyun-Jin Shim, Hyeon-Myeong Shin, Yoo Jung Lee, Hyeonjeong Nam, Su Yeon Kim & Hyung-Sun Youn. (2018) Andrographolide suppresses TRIF-dependent signaling of toll-like receptors by targeting TBK1. International Immunopharmacology 57, pages 172-180.
Crossref
Crossref
Samia Q. Khan, Imran Khan & Vineet Gupta. (2018) CD11b Activity Modulates Pathogenesis of Lupus Nephritis. Frontiers in Medicine 5.
Crossref
Crossref
Peter Moritz Becher, Svenja Hinrichs, Nina Fluschnik, Jan K. Hennigs, Karin Klingel, Stefan Blankenberg, Dirk Westermann & Diana Lindner. (2018) Role of Toll-like receptors and interferon regulatory factors in different experimental heart failure models of diverse etiology: IRF7 as novel cardiovascular stress-inducible factor. PLOS ONE 13:3, pages e0193844.
Crossref
Crossref
Ronghua Wang, Yaoguo Li, Zhiyu Zhou, Qiaolin Liu, Lingbing Zeng & Tiaoyi Xiao. (2018) Involvement of interferon regulatory factor 3 from the barbel chub Squaliobarbus curriculus in the immune response against grass carp reovirus. Gene 648, pages 5-11.
Crossref
Crossref
Shi Jiao, Jingmin Guan, Min Chen, Wenjia Wang, Chuanchuan Li, Yugong Wang, Yunfeng Cheng & Zhaocai Zhou. (2018) Targeting IRF3 as a YAP agonist therapy against gastric cancer. Journal of Experimental Medicine 215:2, pages 699-718.
Crossref
Crossref
Hui Hui Wong, To Sing Fung, Shouguo Fang, Mei Huang, My Tra Le & Ding Xiang Liu. (2018) Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3. Virology 515, pages 165-175.
Crossref
Crossref
芃 袁. (2018) Structural and Non-Structural Proteins of Porcine Epidemic Diarrhea Virus against Congenital Immunity of Host Cells. Advances in Microbiology 07:02, pages 39-47.
Crossref
Crossref
Hong-Ping Liang, Hotta Hak & Jian-Min Ji. (2018) A study on the relationship between HCV NS3 and endogenous IRF-3. European Journal of Inflammation 16, pages 205873921878445.
Crossref
Crossref
James Marion. 2018. Molecular Life Sciences. Molecular Life Sciences
1155
1163
.
Naveed Sabir, Tariq Hussain, Syed Shah, Deming Zhao & Xiangmei Zhou. (2017) IFN-β: A Contentious Player in Host–Pathogen Interaction in Tuberculosis. International Journal of Molecular Sciences 18:12, pages 2725.
Crossref
Crossref
Richard Manivanh, Jesse Mehrbach, David M. Knipe & David A. Leib. (2017) Role of Herpes Simplex Virus 1 γ34.5 in the Regulation of IRF3 Signaling. Journal of Virology 91:23.
Crossref
Crossref
Nathan R. Zemke & Arnold J. Berk. (2017) The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling. Cell Host & Microbe 22:6, pages 789-800.e5.
Crossref
Crossref
Boren Lin, Qi Ke, Haiying Li, Nichole S. Pheifer, David C. Velliquette & Douglas W. Leaman. (2017) Negative regulation of the RLH signaling by the E3 ubiquitin ligase RNF114. Cytokine 99, pages 186-193.
Crossref
Crossref
Kattareeya Kumthip, Darong Yang, Nan L. Li, Yunzhi Zhang, Meiyun Fan, Aarti Sethuraman & Kui Li. (2017) Pivotal role for the ESCRT-II complex subunit EAP30/SNF8 in IRF3-dependent innate antiviral defense. PLOS Pathogens 13:10, pages e1006713.
Crossref
Crossref
Yun-Jia Ning, Kuan Feng, Yuan-Qin Min, Fei Deng, Zhihong Hu & Hualin Wang. (2017) Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase–IRF3 transcription factor interaction and signaling required for interferon induction. Journal of Biological Chemistry 292:40, pages 16722-16733.
Crossref
Crossref
Teslin S. Sandstrom, Nischal Ranganath & Jonathan B. Angel. (2017) Impairment of the type I interferon response by HIV-1: Potential targets for HIV eradication. Cytokine & Growth Factor Reviews 37, pages 1-16.
Crossref
Crossref
Chenyang Yi, Zongzheng Zhao, Shengyu Wang, Xin Sun, Dan Zhang, Xiaomei Sun, Anding Zhang & Meilin Jin. (2017) Influenza A Virus PA Antagonizes Interferon-β by Interacting with Interferon Regulatory Factor 3. Frontiers in Immunology 8.
Crossref
Crossref
Hanzhong Ke & Dongwan Yoo. (2017) The viral innate immune antagonism and an alternative vaccine design for PRRS virus. Veterinary Microbiology 209, pages 75-89.
Crossref
Crossref
Huilin Li, Hui Jin, Yaqian Li, Dejian Liu, Mohamed Frahat Foda, Yunbo Jiang & Rui Luo. (2017) Molecular cloning and functional characterization of duck nucleotide-binding oligomerization domain 1 (NOD1). Developmental & Comparative Immunology 74, pages 82-89.
Crossref
Crossref
Yilong Zhou, Chenxi He, Lin Wang & Baoxue Ge. (2017) Post-translational regulation of antiviral innate signaling. European Journal of Immunology 47:9, pages 1414-1426.
Crossref
Crossref
Udaya S. Rangaswamy, Weijia Wang, Xing Cheng, Patrick McTamney, Danielle Carroll & Hong Jin. (2017)
Newcastle Disease Virus Establishes Persistent Infection in Tumor Cells
In Vitro
: Contribution of the Cleavage Site of Fusion Protein and Second Sialic Acid Binding Site of Hemagglutinin-Neuraminidase
. Journal of Virology 91:16.
Crossref
Crossref
Jing Chen, Jin Li, Jensen H. C. Yiu, Jenny K. W. Lam, Chi-Ming Wong, Bernhard DorweilerAimin Xu & Connie W. Woo. (2017)
TRIF-dependent Toll-like receptor signaling suppresses
Scd1
transcription in hepatocytes and prevents diet-induced hepatic steatosis
. Science Signaling 10:491.
Crossref
Crossref
Tingting Feng, Ta Sun, Guanghao Li, Wen Pan, Kezhen Wang & Jianfeng Dai. (2017) DEAD-Box Helicase DDX25 Is a Negative Regulator of Type I Interferon Pathway and Facilitates RNA Virus Infection. Frontiers in Cellular and Infection Microbiology 7.
Crossref
Crossref
Yajuan Rui, Jiaming Su, Hong Wang, Junliang Chang, Shaohua Wang, Wenwen Zheng, Yong Cai, Wei Wei, James T. Gordy, Richard Markham, Wei Kong, Wenyan Zhang & Xiao-Fang Yu. (2017) Disruption of MDA5-Mediated Innate Immune Responses by the 3C Proteins of Coxsackievirus A16, Coxsackievirus A6, and Enterovirus D68. Journal of Virology 91:13.
Crossref
Crossref
Veronica V. Rezelj, Ping Li, Vidyanath Chaudhary, Richard M. Elliott, Dong-Yan Jin & Benjamin Brennan. (2017)
Differential Antagonism of Human Innate Immune Responses by Tick-Borne
Phlebovirus
Nonstructural Proteins
. mSphere 2:3.
Crossref
Crossref
Bridget Gagné, Nicolas Tremblay, Alex Y. Park, Martin Baril & Daniel Lamarre. (2017) Importin β1 targeting by hepatitis C virus NS3/4A protein restricts IRF3 and NF-κB signaling of IFNB1 antiviral response. Traffic 18:6, pages 362-377.
Crossref
Crossref
Shengyu Wang, Xin Sun, Chenyang Yi, Dan Zhang, Xian Lin, Xiaomei Sun, Huanchun Chen & Meilin Jin. (2017) AGO2 Negatively Regulates Type I Interferon Signaling Pathway by Competition Binding IRF3 with CBP/p300. Frontiers in Cellular and Infection Microbiology 7.
Crossref
Crossref
Jae-Hoon Kim, Min-Eun Park, Chamilani Nikapitiya, Tae-Hwan Kim, Md Bashir Uddin, Hyun-Cheol Lee, Eunhee Kim, Jin Yeul Ma, Jae U. Jung, Chul-Joong Kim & Jong-Soo Lee. (2017) FAS-associated factor-1 positively regulates type I interferon response to RNA virus infection by targeting NLRX1. PLOS Pathogens 13:5, pages e1006398.
Crossref
Crossref
Yan Wang, Yue Yin, Xi Lan, Fei Ye, Kai Tian, Xiaoling Zhao, Huadong Yin, Diyan Li, Hengyong Xu, Yiping Liu & Qing Zhu. (2017) Molecular characterization, expression of chicken TBK1 gene and its effect on IRF3 signaling pathway. PLOS ONE 12:5, pages e0177608.
Crossref
Crossref
Eunhye Lee, Taeyun A. Lee, Ji Hyun Kim, Areum Park, Eun A. Ra, Sujin Kang, Hyun jin Choi, Junhee L. Choi, Hyunbin D. Huh, Ji Eun Lee, Sungwook Lee & Boyoun Park. (2017) CNBP acts as a key transcriptional regulator of sustained expression of interleukin-6. Nucleic Acids Research 45:6, pages 3280-3296.
Crossref
Crossref
Siddharth BakshiJordan TaylorSam StricksonThomas McCartneyPhilip Cohen. (2017) Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β. Biochemical Journal 474:7, pages 1163-1174.
Crossref
Crossref
Mohd Hafeez Faridi, Samia Q. Khan, Wenpu Zhao, Ha Won Lee, Mehmet M. Altintas, Kun Zhang, Vinay Kumar, Andrew R. Armstrong, Carmelo Carmona-Rivera, Jessica M. Dorschner, Abigail M. Schnaith, Xiaobo Li, Yogita Ghodke-Puranik, Erica Moore, Monica Purmalek, Jorge Irizarry-Caro, Tingting Zhang, Rachael Day, Darren Stoub, Victoria Hoffmann, Shehryar Jehangir Khaliqdina, Prachal Bhargava, Ana M. Santander, Marta Torroella-Kouri, Biju Issac, David J. Cimbaluk, Andrew Zloza, Rajeev Prabhakar, Shashank Deep, Meenakshi Jolly, Kwi Hye Koh, Jonathan S. Reichner, Elizabeth M. Bradshaw, JianFeng Chen, Luis F. Moita, Peter S. Yuen, Wanxia Li Tsai, Bhupinder Singh, Jochen Reiser, Swapan K. Nath, Timothy B. Niewold, Roberto I. Vazquez-Padron, Mariana J. Kaplan & Vineet Gupta. (2017) CD11b activation suppresses TLR-dependent inflammation and autoimmunity in systemic lupus erythematosus. Journal of Clinical Investigation 127:4, pages 1271-1283.
Crossref
Crossref
Yohichi Kumaki, Andres M. Salazar, Miles K. Wandersee & Dale L. Barnard. (2017) Prophylactic and therapeutic intranasal administration with an immunomodulator, Hiltonol® (Poly IC:LC), in a lethal SARS-CoV-infected BALB/c mouse model. Antiviral Research 139, pages 1-12.
Crossref
Crossref
Saurabh Chattopadhyay & Ganes C. Sen. (2016) RIG-I-like receptor-induced IRF3 mediated pathway of apoptosis (RIPA): a new antiviral pathway. Protein & Cell 8:3, pages 165-168.
Crossref
Crossref
Divya Ramnath, Elizabeth E. Powell, Glen M. Scholz & Matthew J. Sweet. (2017) The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair. Seminars in Cell & Developmental Biology 61, pages 22-30.
Crossref
Crossref
Meidi Gu, Zhiyong Liu, Rongrong Lai, Si Liu, Wenlong Lin, Chuan Ouyang, Sheng Ye, He Huang & Xiaojian Wang. (2016)
RKIP
and
TBK
1 form a positive feedback loop to promote type I interferon production in innate immunity
. The EMBO Journal 35:23, pages 2553-2565.
Crossref
Crossref
Guanhua Song, Bingyu Liu, Zhihui Li, Haifeng Wu, Peng Wang, Kai Zhao, Guosheng Jiang, Lei Zhang & Chengjiang Gao. (2016) E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1. Nature Immunology 17:12, pages 1342-1351.
Crossref
Crossref
Xibao Zhao, Huihui Zhu, Juan Yu, Hongrui Li, Jiafeng Ge & Weilin Chen. (2016) c-Cbl-mediated ubiquitination of IRF3 negatively regulates IFN-β production and cellular antiviral response. Cellular Signalling 28:11, pages 1683-1693.
Crossref
Crossref
Takako Tabata, Matthew Petitt, June Fang-Hoover, Martin Zydek & Lenore Pereira. (2016) Persistent Cytomegalovirus Infection in Amniotic Membranes of the Human Placenta. The American Journal of Pathology 186:11, pages 2970-2986.
Crossref
Crossref
Ryo Hayakari, Tomoh Matsumiya, Fei Xing, Hidemi Yoshida, Makoto Hayakari & Tadaatsu Imaizumi. (2016) Critical Role of IRF-3 in the Direct Regulation of dsRNA-Induced Retinoic Acid-Inducible Gene-I (RIG-I) Expression. PLOS ONE 11:9, pages e0163520.
Crossref
Crossref
Yang Ding, Jingqun Ao, Xiaohong Huang & Xinhua Chen. (2016) Identification of Two Subgroups of Type I IFNs in Perciforme Fish Large Yellow Croaker Larimichthys crocea Provides Novel Insights into Function and Regulation of Fish Type I IFNs. Frontiers in Immunology 7.
Crossref
Crossref
Keerthi Gottipati, Luis Marcelo F. Holthauzen, Nicolas Ruggli & Kyung H. Choi. (2016)
Pestivirus N
pro
Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer
. Journal of Virology 90:17, pages 7740-7747.
Crossref
Crossref
Xueying Tang, Baoyu Huang, Linlin Zhang, Li Li & Guofan Zhang. (2016) TANK-binding kinase-1 broadly affects oyster immune response to bacteria and viruses. Fish & Shellfish Immunology 56, pages 330-335.
Crossref
Crossref
Lauren T. Gates & Joanna L. Shisler. (2016) cFLIPL Interrupts IRF3–CBP–DNA Interactions To Inhibit IRF3-Driven Transcription. The Journal of Immunology 197:3, pages 923-933.
Crossref
Crossref
Nicolas Tremblay, Martin Baril, Laurent Chatel-Chaix, Salwa Es-Saad, Alex Young Park, Robert K. Koenekoop & Daniel Lamarre. (2016) Spliceosome SNRNP200 Promotes Viral RNA Sensing and IRF3 Activation of Antiviral Response. PLOS Pathogens 12:7, pages e1005772.
Crossref
Crossref
Manju Kumari, Xun Wang, Louise Lantier, Anna Lyubetskaya, Jun Eguchi, Sona Kang, Danielle Tenen, Hyun Cheol Roh, Xingxing Kong, Lawrence Kazak, Rasheed Ahmad & Evan D. Rosen. (2016) IRF3 promotes adipose inflammation and insulin resistance and represses browning. Journal of Clinical Investigation 126:8, pages 2839-2854.
Crossref
Crossref
Li-Ling Lin, Chao-Cheng Huang, Chia-Ling Wu, Min-Tsui Wu, Wen-Ming Hsu & Jiin-Haur Chuang. (2016) Downregulation of c-Myc is involved in TLR3-mediated tumor death of neuroblastoma xenografts. Laboratory Investigation 96:7, pages 719-730.
Crossref
Crossref
Yuko Tsuchiya, Nao Jounai, Fumihiko Takeshita, Ken J. Ishii & Kenji Mizuguchi. (2016) Ligand-induced Ordering of the C-terminal Tail Primes STING for Phosphorylation by TBK1. EBioMedicine 9, pages 87-96.
Crossref
Crossref
Christine L. White, Patricia M. Kessler, Benjamin K. Dickerman, Keiko Ozato & Ganes C. Sen. (2016) Interferon Regulatory Factor 8 (IRF8) Impairs Induction of Interferon Induced with Tetratricopeptide Repeat Motif (IFIT) Gene Family Members. Journal of Biological Chemistry 291:26, pages 13535-13545.
Crossref
Crossref
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