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Transcriptional Regulation

The CCR4 and CAF1 Proteins of the CCR4-NOT Complex Are Physically and Functionally Separated from NOT2, NOT4, and NOT5

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Pages 6642-6651 | Received 02 Nov 1998, Accepted 14 Jun 1999, Published online: 28 Mar 2023

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Shun Hosoyamada, Mariko Sasaki & Takehiko Kobayashi. (2020) The CCR4-NOT Complex Maintains Stability and Transcription of rRNA Genes by Repressing Antisense Transcripts. Molecular and Cellular Biology 40:1.
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Fabienne Mauxion, Brigitte Prève & Bertrand Séraphin. (2013) C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complex. RNA Biology 10:2, pages 267-276.
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Praveen Bawankar, Belinda Loh, Lara Wohlbold, Steffen Schmidt & Elisa Izaurralde. (2013) NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain. RNA Biology 10:2, pages 228-244.
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Cyril Berthet, Anne-Marie Morera, Marie-Jeanne Asensio, Marie-Agnes Chauvin, Anne-Pierre Morel, Frederique Dijoud, Jean-Pierre Magaud, Philippe Durand & Jean-Pierre Rouault. (2004) CCR4-Associated Factor CAF1 Is an Essential Factor for Spermatogenesis. Molecular and Cellular Biology 24:13, pages 5808-5820.
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Sylke Meyer, Claudia Temme & Elmar Wahle. (2004) Messenger RNA Turnover in Eukaryotes: Pathways and Enzymes. Critical Reviews in Biochemistry and Molecular Biology 39:4, pages 197-216.
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Cécile Deluen, Nicole James, Laurent Maillet, Miguel Molinete, Grégory Theiler, Marc Lemaire, Nicole Paquet & Martine A. Collart. (2002) The Ccr4-Not Complex and yTAF1 (yTafII130p/yTafII145p) Show Physical and Functional Interactions. Molecular and Cellular Biology 22:19, pages 6735-6749.
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Kevin J. Hart, Jenna Oberstaller, Michael P. Walker, Allen M. Minns, Mark F. Kennedy, Ian Padykula, John H. Adams & Scott E. Lindner. (2019) Plasmodium male gametocyte development and transmission are critically regulated by the two putative deadenylases of the CAF1/CCR4/NOT complex. PLOS Pathogens 15:1, pages e1007164.
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Tobias Raisch, Felix Sandmeir, Oliver Weichenrieder, Eugene Valkov & Elisa Izaurralde. (2018) Structural and biochemical analysis of a NOT1 MIF4G-like domain of the CCR4-NOT complex. Journal of Structural Biology 204:3, pages 388-395.
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Hongfeng Chen, Tirupataiah Sirupangi, Zhao-Hui Wu, Daniel L. Johnson & R. Nicholas Laribee. (2018) The conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function. Scientific Reports 8:1.
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Clément Chapat, Kamel Chettab, Pierre Simonet, Peng Wang, Pierre De La Grange, Muriel Le Romancer & Laura Corbo. (2017) Alternative splicing of CNOT7 diversifies CCR4–NOT functions. Nucleic Acids Research 45:14, pages 8508-8523.
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Martine A. Collart, Sari Kassem & Zoltan Villanyi. (2017) Mutations in the NOT Genes or in the Translation Machinery Similarly Display Increased Resistance to Histidine Starvation. Frontiers in Genetics 8.
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Wei-Lun Chou, Yue-Lin Chung, Jhen-Cheng Fang & Chung-An Lu. (2016) Novel interaction between CCR4 and CAF1 in rice CCR4–NOT deadenylase complex. Plant Molecular Biology 93:1-2, pages 79-96.
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Jonas Goossens, Nathan De Geyter, Alan Walton, Dominique Eeckhout, Jan Mertens, Jacob Pollier, Jennifer Fiallos-Jurado, Annick De Keyser, Rebecca De Clercq, Jelle Van Leene, Kris Gevaert, Geert De Jaeger, Sofie Goormachtig & Alain Goossens. (2016) Isolation of protein complexes from the model legume Medicago truncatula by tandem affinity purification in hairy root cultures . The Plant Journal 88:3, pages 476-489.
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James A.W. Stowell, Michael W. Webster, Alexander Kögel, Jana Wolf, Kathryn L. Shelley & Lori A. Passmore. (2016) Reconstitution of Targeted Deadenylation by the Ccr4-Not Complex and the YTH Domain Protein Mmi1. Cell Reports 17:8, pages 1978-1989.
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Marta Ukleja, José María Valpuesta, Andrzej Dziembowski & Jorge Cuellar. (2016) Beyond the known functions of the CCR4-NOT complex in gene expression regulatory mechanisms. BioEssays 38:10, pages 1048-1058.
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Najwa Alhusaini & Jeff Coller. (2016) The deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping. RNA 22:5, pages 709-721.
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Marta Ukleja, Jorge Cuellar, Aleksandra Siwaszek, Joanna M. Kasprzak, Mariusz Czarnocki-Cieciura, Janusz M. Bujnicki, Andrzej Dziembowski & Jose M. Valpuesta. (2016) The architecture of the Schizosaccharomyces pombe CCR4-NOT complex. Nature Communications 7:1.
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Duc-Cuong Bui, Hokyoung Son, Ji Young Shin, Jin-Cheol Kim, Hun Kim, Gyung Ja Choi & Yin-Won Lee. (2016) The FgNot3 Subunit of the Ccr4-Not Complex Regulates Vegetative Growth, Sporulation, and Virulence in Fusarium graminearum. PLOS ONE 11:1, pages e0147481.
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Shruti Waghray, Clay Williams, Joshua J. Coon & Marvin Wickens. (2015) Xenopus CAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo . RNA 21:7, pages 1335-1345.
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Varun Bhaskar, Jérôme Basquin & Elena Conti. (2015) Architecture of the Ubiquitylation Module of the Yeast Ccr4-Not Complex. Structure 23:5, pages 921-928.
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Yo-Taro Shirai, Toru Suzuki, Masahiro Morita, Akinori Takahashi & Tadashi Yamamoto. (2014) Multifunctional roles of the mammalian CCR4–NOT complex in physiological phenomena. Frontiers in Genetics 5.
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Toshifumi Inada & Shiho Makino. (2014) Novel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation. Frontiers in Genetics 5.
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Kun Xu, Yuwei Bai, Aili Zhang, Qionglin Zhang & Mark G. Bartlam. (2014) Insights into the structure and architecture of the CCR4–NOT complex. Frontiers in Genetics 5.
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David Halter, Martine A. Collart & Olesya O. Panasenko. (2014) The Not4 E3 Ligase and CCR4 Deadenylase Play Distinct Roles in Protein Quality Control. PLoS ONE 9:1, pages e86218.
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Ryo Matsuda, Ken Ikeuchi, Sene Nomura & Toshifumi Inada. (2014) Protein quality control systems associated with no-go and nonstop mRNA surveillance in yeast. Genes to Cells 19:1, pages 1-12.
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Marco Nousch, Nora Techritz, Daniel Hampel, Sophia Millonigg & Christian R. Eckmann. (2013) The Ccr4-Not deadenylase complex constitutes the major poly(A) removal activity in C. elegans . Journal of Cell Science.
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Valentin Färber, Esteban Erben, Sahil Sharma, Georg Stoecklin & Christine Clayton. (2013) Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs. Nucleic Acids Research 41:2, pages 1211-1222.
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Yajun Cui, Yueh-Chin Chiang, Palaniswamy Viswanathan, Darren J. Lee & Clyde L. Denis. (2012) SPT5 affects the rate of mRNA degradation and physically interacts with CCR4 but does not control mRNA deadenylation. American Journal of Molecular Biology 02:01, pages 11-20.
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Jennifer A. Kruk, Arnob Dutta, Jianhua Fu, David S. Gilmour & Joseph C. Reese. (2011) The multifunctional Ccr4–Not complex directly promotes transcription elongation. Genes & Development 25:6, pages 581-593.
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Guangzuo Luo, Michael Costanzo, Charles Boone & Robert C. Dickson. (2011) Nutrients and the Pkh1/2 and Pkc1 Protein Kinases Control mRNA Decay and P-body Assembly in Yeast. Journal of Biological Chemistry 286:11, pages 8759-8770.
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Claudia Temme, Lianbing Zhang, Elisabeth Kremmer, Christian Ihling, Aymeric Chartier, Andrea Sinz, Martine Simonelig & Elmar Wahle. (2010) Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation . RNA 16:7, pages 1356-1370.
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