Molecular and Cellular Biology, Volume 19, Issue 10 (1999)

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Molecular and Cellular Biology, Volume 19, Issue 10 (1999)

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Gene Expression

Article
Identification of a Novel Dexamethasone-Sensitive RNA-Destabilizing Region on Rat Monocyte Chemoattractant Protein 1 mRNA
Michael Poon, Bin Liu & Mark B. Taubman
Pages: 6471-6478
Published online: 28 Mar 2023
AbstractforIdentification of a Novel Dexamethasone-Sensitive RNA-Destabilizing Region on Rat Monocyte Chemoattractant Protein 1 mRNA | Full Text | References | PDF (2 MB)
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Article
Evaluating Group I Intron Catalytic Efficiency in Mammalian Cells
Meredith B. Long & Bruce A. Sullenger
Pages: 6479-6487
Published online: 28 Mar 2023
AbstractforEvaluating Group I Intron Catalytic Efficiency in Mammalian Cells | Full Text | References | PDF (451.2 KB)
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Article
Circadian Expression of the Steroid 15 α-Hydroxylase (Cyp2a4) and Coumarin 7-Hydroxylase (Cyp2a5) Genes in Mouse Liver Is Regulated by the PAR Leucine Zipper Transcription Factor DBP
Daniel J. Lavery, Luis Lopez-Molina, Raphael Margueron, Fabienne Fleury-Olela, François Conquet, Ueli Schibler & Claude Bonfils
Pages: 6488-6499
Published online: 28 Mar 2023
AbstractforCircadian Expression of the Steroid 15 α-Hydroxylase (Cyp2a4) and Coumarin 7-Hydroxylase (Cyp2a5) Genes in Mouse Liver Is Regulated by the PAR Leucine Zipper Transcription Factor DBP | Full Text | References | PDF (1.3 MB)
  • 64 Views
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Article
Genetic and Physical Interactions Involving the Yeast Nuclear Cap-Binding Complex
Puri Fortes, Joanna Kufel, Maarten Fornerod, Maria Polycarpou-Schwarz, Denis Lafontaine, David Tollervey & Iain W. Mattaj
Pages: 6543-6553
Published online: 28 Mar 2023
AbstractforGenetic and Physical Interactions Involving the Yeast Nuclear Cap-Binding Complex | Full Text | References | PDF (1.5 MB)
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Article
Spliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner
Veronica A. Raker, Klaus Hartmuth, Berthold Kastner & Reinhard Lührmann
Pages: 6554-6565
Published online: 28 Mar 2023
AbstractforSpliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner | Full Text | References | PDF (2.5 MB)
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Article
Yeast Upf Proteins Required for RNA Surveillance Affect Global Expression of the Yeast Transcriptome
Michael J. Lelivelt & Michael R. Culbertson
Pages: 6710-6719
Published online: 28 Mar 2023
AbstractforYeast Upf Proteins Required for RNA Surveillance Affect Global Expression of the Yeast Transcriptome | Full Text | References | PDF (122.5 KB)
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Article
Protein Kinase A Regulates Cholinergic Gene Expression in PC12 Cells: REST4 Silences the Silencing Activity of Neuron-Restrictive Silencer Factor/REST
Masahito Shimojo, Alice J. Paquette, David J. Anderson & Louis B. Hersh
Pages: 6788-6795
Published online: 28 Mar 2023
AbstractforProtein Kinase A Regulates Cholinergic Gene Expression in PC12 Cells: REST4 Silences the Silencing Activity of Neuron-Restrictive Silencer Factor/REST | Full Text | References | PDF (1.5 MB)
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Article
Characterization of a Protein Complex Containing Spliceosomal Proteins SAPs 49, 130, 145, and 155
Biplab K. Das, Ling Xia, Leon Palandjian, Or Gozani, Yung Chyung & Robin Reed
Pages: 6796-6802
Published online: 28 Mar 2023
AbstractforCharacterization of a Protein Complex Containing Spliceosomal Proteins SAPs 49, 130, 145, and 155 | Full Text | References | PDF (1.9 MB)
  • 22 Views
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Article
Delayed Translational Silencing of Ceruloplasmin Transcript in Gamma Interferon-Activated U937 Monocytic Cells: Role of the 3′ Untranslated Region
Barsanjit Mazumder & Paul L. Fox
Pages: 6898-6905
Published online: 28 Mar 2023
AbstractforDelayed Translational Silencing of Ceruloplasmin Transcript in Gamma Interferon-Activated U937 Monocytic Cells: Role of the 3′ Untranslated Region | Full Text | References | PDF (1.8 MB)
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Article
Nucleolar Factors Direct the 2′-O-Ribose Methylation and Pseudouridylation of U6 Spliceosomal RNA
Philippe Ganot, Beáta E. Jády, Marie-Line Bortolin, Xavier Darzacq & Tamás Kiss
Pages: 6906-6917
Published online: 28 Mar 2023
AbstractforNucleolar Factors Direct the 2′-O-Ribose Methylation and Pseudouridylation of U6 Spliceosomal RNA | Full Text | References | PDF (2.1 MB)
  • 18 Views
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Article
The Protein Kinase Clk/Sty Directly Modulates SR Protein Activity: Both Hyper- and Hypophosphorylation Inhibit Splicing
Jayendra Prasad, Karen Colwill, Tony Pawson & James L. Manley
Pages: 6991-7000
Published online: 28 Mar 2023
AbstractforThe Protein Kinase Clk/Sty Directly Modulates SR Protein Activity: Both Hyper- and Hypophosphorylation Inhibit Splicing | Full Text | References | PDF (1.6 MB)
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Article
Variegated Expression of the Endogenous Immunoglobulin Heavy-Chain Gene in the Absence of the Intronic Locus Control Region
Diana Ronai, Maribel Berru & Marc J. Shulman
Pages: 7031-7040
Published online: 28 Mar 2023
AbstractforVariegated Expression of the Endogenous Immunoglobulin Heavy-Chain Gene in the Absence of the Intronic Locus Control Region | Full Text | References | PDF (241 KB)
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Article
Regulation of RelA Subcellular Localization by a Putative Nuclear Export Signal and p50
Edward W. Harhaj & Shao-Cong Sun
Pages: 7088-7095
Published online: 28 Mar 2023
AbstractforRegulation of RelA Subcellular Localization by a Putative Nuclear Export Signal and p50 | Full Text | References | PDF (3.5 MB)
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Cell Growth and Development

Article
Mouse Receptor Interacting Protein 3 Does Not Contain a Caspase-Recruiting or a Death Domain but Induces Apoptosis and Activates NF-κB
Nanette J. Pazdernik, David B. Donner, Mark G. Goebl & Maureen A. Harrington
Pages: 6500-6508
Published online: 28 Mar 2023
AbstractforMouse Receptor Interacting Protein 3 Does Not Contain a Caspase-Recruiting or a Death Domain but Induces Apoptosis and Activates NF-κB | Full Text | References | PDF (1.3 MB)
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Article
Both TEL and AML-1 Contribute Repression Domains to the t(12;21) Fusion Protein
Randy Fenrick, Joseph M. Amann, Bart Lutterbach, Lilin Wang, Jennifer J. Westendorf, James R. Downing & Scott W. Hiebert
Pages: 6566-6574
Published online: 28 Mar 2023
AbstractforBoth TEL and AML-1 Contribute Repression Domains to the t(12;21) Fusion Protein | Full Text | References | PDF (697.6 KB)
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Article
Rpn9 Is Required for Efficient Assembly of the Yeast 26S Proteasome
Junko Takeuchi, Masahiro Fujimuro, Hideyosi Yokosawa, Keiji Tanaka & Akio Toh-e
Pages: 6575-6584
Published online: 28 Mar 2023
AbstractforRpn9 Is Required for Efficient Assembly of the Yeast 26S Proteasome | Full Text | References | PDF (6.1 MB)
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Article
The Borgs, a New Family of Cdc42 and TC10 GTPase-Interacting Proteins
Gérard Joberty, Richard R. Perlungher & Ian G. Macara
Pages: 6585-6597
Published online: 28 Mar 2023
AbstractforThe Borgs, a New Family of Cdc42 and TC10 GTPase-Interacting Proteins | Full Text | References | PDF (3.3 MB)
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  • 108 CrossRef citations
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Article
The Oncogenic 70Z Cbl Mutation Blocks the Phosphotyrosine Binding Domain-Dependent Negative Regulation of ZAP-70 by c-Cbl in Jurkat T Cells
Jeroen E. M. van Leeuwen, Paul K. Paik & Lawrence E. Samelson
Pages: 6652-6664
Published online: 28 Mar 2023
AbstractforThe Oncogenic 70Z Cbl Mutation Blocks the Phosphotyrosine Binding Domain-Dependent Negative Regulation of ZAP-70 by c-Cbl in Jurkat T Cells | Full Text | References | PDF (1.8 MB)
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Article
TANK Potentiates Tumor Necrosis Factor Receptor-Associated Factor-Mediated c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase Activation through the Germinal Center Kinase Pathway
Arnold I-Dah Chin, Junyan Shu, Chong Shan Shi, Zhengbin Yao, John H. Kehrl & Genhong Cheng
Pages: 6665-6672
Published online: 28 Mar 2023
AbstractforTANK Potentiates Tumor Necrosis Factor Receptor-Associated Factor-Mediated c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase Activation through the Germinal Center Kinase Pathway | Full Text | References | PDF (1.5 MB)
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Article
The BH3 Domain of Bcl-xS Is Required for Inhibition of the Antiapoptotic Function of Bcl-xL
Brian S. Chang, Ameeta Kelekar, Marian H. Harris, John E. Harlan, Stephen W. Fesik & Craig B. Thompson
Pages: 6673-6681
Published online: 28 Mar 2023
AbstractforThe BH3 Domain of Bcl-xS Is Required for Inhibition of the Antiapoptotic Function of Bcl-xL | Full Text | References | PDF (560.4 KB)
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Article
Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways
Helmut Holtmann, Reinhard Winzen, Pamela Holland, Solveig Eickemeier, Elke Hoffmann, David Wallach, Nikolai L. Malinin, Jonathan A. Cooper, Klaus Resch & Michael Kracht
Pages: 6742-6753
Published online: 28 Mar 2023
AbstractforInduction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways | Full Text | References | PDF (1.6 MB)
  • 27 Views
  • 232 CrossRef citations
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Article
The Acidic Domain and First Immunoglobulin-Like Loop of Fibroblast Growth Factor Receptor 2 Modulate Downstream Signaling through Glycosaminoglycan Modification
Kazushige Sakaguchi, Matthew V. Lorenzi, Donald P. Bottaro & Toru Miki
Pages: 6754-6764
Published online: 28 Mar 2023
AbstractforThe Acidic Domain and First Immunoglobulin-Like Loop of Fibroblast Growth Factor Receptor 2 Modulate Downstream Signaling through Glycosaminoglycan Modification | Full Text | References | PDF (2.6 MB)
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Article
G Alpha-q/11 Protein Plays a Key Role in Insulin-Induced Glucose Transport in 3T3-L1 Adipocytes
Takeshi Imamura, Peter Vollenweider, Katsuya Egawa, Martin Clodi, Kenichi Ishibashi, Naoki Nakashima, Satoshi Ugi, John W. Adams, Joan Heller Brown & Jerrold M. Olefsky
Pages: 6765-6774
Published online: 28 Mar 2023
AbstractforG Alpha-q/11 Protein Plays a Key Role in Insulin-Induced Glucose Transport in 3T3-L1 Adipocytes | Full Text | References | PDF (1.7 MB)
  • 38 Views
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Article
Erf2, a Novel Gene Product That Affects the Localization and Palmitoylation of Ras2 in Saccharomyces cerevisiae
Doug J. Bartels, David A. Mitchell, Xiangwen Dong & Robert J. Deschenes
Pages: 6775-6787
Published online: 28 Mar 2023
AbstractforErf2, a Novel Gene Product That Affects the Localization and Palmitoylation of Ras2 in Saccharomyces cerevisiae | Full Text | References | PDF (1.1 MB)
  • 83 Views
  • 144 CrossRef citations
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Article
Controlled Dimerization of ErbB Receptors Provides Evidence for Differential Signaling by Homo- and Heterodimers
Senthil K. Muthuswamy, Michael Gilman & Joan S. Brugge
Pages: 6845-6857
Published online: 28 Mar 2023
AbstractforControlled Dimerization of ErbB Receptors Provides Evidence for Differential Signaling by Homo- and Heterodimers | Full Text | References | PDF (1.7 MB)
  • 125 Views
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Article
Inhibition of Src Family Kinases by a Combinatorial Action of 5′-AMP and Small Heat Shock Proteins, Identified from the Adult Heart
Vijaykumar S. Kasi & Dhandapani Kuppuswamy
Pages: 6858-6871
Published online: 28 Mar 2023
AbstractforInhibition of Src Family Kinases by a Combinatorial Action of 5′-AMP and Small Heat Shock Proteins, Identified from the Adult Heart | Full Text | References | PDF (2.1 MB)
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Article
Functional Characterization of Rpn3 Uncovers a Distinct 19S Proteasomal Subunit Requirement for Ubiquitin-Dependent Proteolysis of Cell Cycle Regulatory Proteins in Budding Yeast
Eric Bailly & Steven I. Reed
Pages: 6872-6890
Published online: 28 Mar 2023
AbstractforFunctional Characterization of Rpn3 Uncovers a Distinct 19S Proteasomal Subunit Requirement for Ubiquitin-Dependent Proteolysis of Cell Cycle Regulatory Proteins in Budding Yeast | Full Text | References | PDF (4.7 MB)
  • 9 Views
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Article
Bcr-Abl with an SH3 Deletion Retains the Ability To Induce a Myeloproliferative Disease in Mice, yet c-Abl Activated by an SH3 Deletion Induces Only Lymphoid Malignancy
Alec W. Gross, Xiaowu Zhang & Ruibao Ren
Pages: 6918-6928
Published online: 28 Mar 2023
AbstractforBcr-Abl with an SH3 Deletion Retains the Ability To Induce a Myeloproliferative Disease in Mice, yet c-Abl Activated by an SH3 Deletion Induces Only Lymphoid Malignancy | Full Text | References | PDF (515.2 KB)
  • 4 Views
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Article
The Morphogenesis Checkpoint in Saccharomyces cerevisiae: Cell Cycle Control of Swe1p Degradation by Hsl1p and Hsl7p
John N. McMillan, Mark S. Longtine, Rey A. L. Sia, Chandra L. Theesfeld, Elaine S. G. Bardes, John R. Pringle & Daniel J. Lew
Pages: 6929-6939
Published online: 28 Mar 2023
AbstractforThe Morphogenesis Checkpoint in Saccharomyces cerevisiae: Cell Cycle Control of Swe1p Degradation by Hsl1p and Hsl7p | Full Text | References | PDF (1.8 MB)
  • 13 Views
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Article
Cas Mediates Transcriptional Activation of the Serum Response Element by Src
Yaron Hakak & G. Steven Martin
Pages: 6953-6962
Published online: 28 Mar 2023
AbstractforCas Mediates Transcriptional Activation of the Serum Response Element by Src | Full Text | References | PDF (832.8 KB)
  • 5 Views
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Article
Altered Telomere Nuclear Matrix Interactions and Nucleosomal Periodicity in Ataxia Telangiectasia Cells before and after Ionizing Radiation Treatment
Lubomir B. Smilenov, Sonu Dhar & Tej K. Pandita
Pages: 6963-6971
Published online: 28 Mar 2023
AbstractforAltered Telomere Nuclear Matrix Interactions and Nucleosomal Periodicity in Ataxia Telangiectasia Cells before and after Ionizing Radiation Treatment | Full Text | References | PDF (1.1 MB)
  • 4 Views
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Article
Rsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of RNA Polymerase II in Saccharomyces cerevisiae
Sylvie L. Beaudenon, Maria R. Huacani, Guangli Wang, Donald P. McDonnell & Jon M. Huibregtse
Pages: 6972-6979
Published online: 28 Mar 2023
AbstractforRsp5 Ubiquitin-Protein Ligase Mediates DNA Damage-Induced Degradation of the Large Subunit of RNA Polymerase II in Saccharomyces cerevisiae | Full Text | References | PDF (1.5 MB)
  • 70 Views
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Article
Targeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27Kip1 Activity
Tateki Tsutsui, Bahar Hesabi, David S. Moons, Pier Paolo Pandolfi, Kimberly S. Hansel, Andrew Koff & Hiroaki Kiyokawa
Pages: 7011-7019
Published online: 28 Mar 2023
AbstractforTargeted Disruption of CDK4 Delays Cell Cycle Entry with Enhanced p27Kip1 Activity | Full Text | References | PDF (2 MB)
  • 51 Views
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Article
Substrate Targeting of the Yeast Cyclin-Dependent Kinase Pho85p by the Cyclin Pcl10p
Wayne A. Wilson, Alan M. Mahrenholz & Peter J. Roach
Pages: 7020-7030
Published online: 28 Mar 2023
AbstractforSubstrate Targeting of the Yeast Cyclin-Dependent Kinase Pho85p by the Cyclin Pcl10p | Full Text | References | PDF (1.3 MB)
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Article
NORF5/HUG1 Is a Component of the MEC1-Mediated Checkpoint Response to DNA Damage and Replication Arrest in Saccharomyces cerevisiae
Munira A. Basrai, Victor E. Velculescu, Kenneth W. Kinzler & Philip Hieter
Pages: 7041-7049
Published online: 28 Mar 2023
AbstractforNORF5/HUG1 Is a Component of the MEC1-Mediated Checkpoint Response to DNA Damage and Replication Arrest in Saccharomyces cerevisiae | Full Text | References | PDF (2.2 MB)
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Article
Leukemic HRX Fusion Proteins Inhibit GADD34-Induced Apoptosis and Associate with the GADD34 and hSNF5/INI1 Proteins
Haskell T. Adler, Rebecca Chinery, Daniel Y. Wu, Steven J. Kussick, John M. Payne, Albert J. Fornace Jr. & Douglas C. Tkachuk
Pages: 7050-7060
Published online: 28 Mar 2023
AbstractforLeukemic HRX Fusion Proteins Inhibit GADD34-Induced Apoptosis and Associate with the GADD34 and hSNF5/INI1 Proteins | Full Text | References | PDF (1.2 MB)
  • 35 Views
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Article
Growth Retardation, DNA Repair Defects, and Lack of Spermatogenesis in BRCA1-Deficient Mice
Victoria L. Cressman, Dana C. Backlund, Anna V. Avrutskaya, Steven A. Leadon, Virginia Godfrey & Beverly H. Koller
Pages: 7061-7075
Published online: 28 Mar 2023
AbstractforGrowth Retardation, DNA Repair Defects, and Lack of Spermatogenesis in BRCA1-Deficient Mice | Full Text | References | PDF (2.8 MB)
  • 19 Views
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Article
Bone Morphogenetic Proteins Induce Cardiomyocyte Differentiation through the Mitogen-Activated Protein Kinase Kinase Kinase TAK1 and Cardiac Transcription Factors Csx/Nkx-2.5 and GATA-4
Koshiro Monzen, Ichiro Shiojima, Yukio Hiroi, Sumiyo Kudoh, Toru Oka, Eiki Takimoto, Doubun Hayashi, Toru Hosoda, Akemi Habara-Ohkubo, Takashi Nakaoka, Toshiro Fujita, Yoshio Yazaki & Issei Komuro
Pages: 7096-7105
Published online: 28 Mar 2023
AbstractforBone Morphogenetic Proteins Induce Cardiomyocyte Differentiation through the Mitogen-Activated Protein Kinase Kinase Kinase TAK1 and Cardiac Transcription Factors Csx/Nkx-2.5 and GATA-4 | Full Text | References | PDF (1.3 MB)
  • 57 Views
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Article
Developmental Effects of Ectopic Expression of the Glucocorticoid Receptor DNA Binding Domain Are Alleviated by an Amino Acid Substitution That Interferes with Homeodomain Binding
Jun Ming Wang, Gratien G. Préfontaine, Madeleine E. Lemieux, Louise Pope, Marie-Andrée Akimenko & Robert J. G. Haché
Pages: 7106-7122
Published online: 28 Mar 2023
AbstractforDevelopmental Effects of Ectopic Expression of the Glucocorticoid Receptor DNA Binding Domain Are Alleviated by an Amino Acid Substitution That Interferes with Homeodomain Binding | Full Text | References | PDF (2.7 MB)
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Article
Hsl7 Localizes to a Septin Ring and Serves as an Adapter in a Regulatory Pathway That Relieves Tyrosine Phosphorylation of Cdc28 Protein Kinase in Saccharomyces cerevisiae
Mark J. Shulewitz, Carla J. Inouye & Jeremy Thorner
Pages: 7123-7137
Published online: 28 Mar 2023
AbstractforHsl7 Localizes to a Septin Ring and Serves as an Adapter in a Regulatory Pathway That Relieves Tyrosine Phosphorylation of Cdc28 Protein Kinase in Saccharomyces cerevisiae | Full Text | References | PDF (3.2 MB)
  • 22 Views
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Article
Regulation of Glycogen Synthase Kinase 3β and Downstream Wnt Signaling by Axin
Chester M. Hedgepeth, Matthew A. Deardorff, Kathleen Rankin & Peter S. Klein
Pages: 7147-7157
Published online: 28 Mar 2023
AbstractforRegulation of Glycogen Synthase Kinase 3β and Downstream Wnt Signaling by Axin | Full Text | References | PDF (1.6 MB)
  • 19 Views
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Article
Concerted Regulation of Wild-Type p53 Nuclear Accumulation and Activation by S100B and Calcium-Dependent Protein Kinase C
Christian Scotto, Christian Delphin, Jean Christophe Deloulme & Jacques Baudier
Pages: 7168-7180
Published online: 28 Mar 2023
AbstractforConcerted Regulation of Wild-Type p53 Nuclear Accumulation and Activation by S100B and Calcium-Dependent Protein Kinase C | Full Text | References | PDF (2.7 MB)
  • 20 Views
  • 49 CrossRef citations
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Article
C/EBPβ Modulates the Early Events of Keratinocyte Differentiation Involving Growth Arrest and Keratin 1 and Keratin 10 Expression
Songyun Zhu, Hye-Sun Oh, Minsub Shim, Esta Sterneck, Peter F. Johnson & Robert C. Smart
Pages: 7181-7190
Published online: 28 Mar 2023
AbstractforC/EBPβ Modulates the Early Events of Keratinocyte Differentiation Involving Growth Arrest and Keratin 1 and Keratin 10 Expression | Full Text | References | PDF (1,015.4 KB)
  • 62 Views
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Article
Multiple Signaling Pathways of the Insulin-Like Growth Factor 1 Receptor in Protection from Apoptosis
Francesca Peruzzi, Marco Prisco, Michael Dews, Paolo Salomoni, Emanuela Grassilli, Gaetano Romano, Bruno Calabretta & Renato Baserga
Pages: 7203-7215
Published online: 28 Mar 2023
AbstractforMultiple Signaling Pathways of the Insulin-Like Growth Factor 1 Receptor in Protection from Apoptosis | Full Text | References | PDF (1.9 MB)
  • 55 Views
  • 364 CrossRef citations
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Article
ATP-Dependent Inactivation and Sequestration of Ornithine Decarboxylase by the 26S Proteasome Are Prerequisites for Degradation
Yasuko Murakami, Senya Matsufuji, Shin-Ichi Hayashi, Nobuyuki Tanahashi & Keiji Tanaka
Pages: 7216-7227
Published online: 28 Mar 2023
AbstractforATP-Dependent Inactivation and Sequestration of Ornithine Decarboxylase by the 26S Proteasome Are Prerequisites for Degradation | Full Text | References | PDF (1.2 MB)
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Article
The JIP Group of Mitogen-Activated Protein Kinase Scaffold Proteins
Jun Yasuda, Alan J. Whitmarsh, Julie Cavanagh, Manoj Sharma & Roger J. Davis
Pages: 7245-7254
Published online: 28 Mar 2023
AbstractforThe JIP Group of Mitogen-Activated Protein Kinase Scaffold Proteins | Full Text | References | PDF (2 MB)
  • 73 Views
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Article
zfh-1, the Drosophila Homologue of ZEB, Is a Transcriptional Repressor That Regulates Somatic Myogenesis
Antonio A. Postigo, Ellen Ward, James B. Skeath & Douglas C. Dean
Pages: 7255-7263
Published online: 28 Mar 2023
Abstractforzfh-1, the Drosophila Homologue of ZEB, Is a Transcriptional Repressor That Regulates Somatic Myogenesis | Full Text | References | PDF (904.4 KB)
  • 62 Views
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Article
De Novo Synthesis of Sphingolipids Is Required for Cell Survival by Down-Regulating c-Jun N-Terminal Kinase in Drosophila Imaginal Discs
Takashi Adachi-Yamada, Tomokazu Gotoh, Isamu Sugimura, Minoru Tateno, Yasuyoshi Nishida, Tomoya Onuki & Hideyuki Date
Pages: 7276-7286
Published online: 28 Mar 2023
AbstractforDe Novo Synthesis of Sphingolipids Is Required for Cell Survival by Down-Regulating c-Jun N-Terminal Kinase in Drosophila Imaginal Discs | Full Text | References | PDF (2.8 MB)
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Transcriptional Regulation

Article
Modulation of Transcriptional Activation and Coactivator Interaction by a Splicing Variation in the F Domain of Nuclear Receptor Hepatocyte Nuclear Factor 4α1
Frances M. Sladek, Michael D. Ruse Jr., Luviminda Nepomuceno, Shih-Ming Huang & Michael R. Stallcup
Pages: 6509-6522
Published online: 28 Mar 2023
AbstractforModulation of Transcriptional Activation and Coactivator Interaction by a Splicing Variation in the F Domain of Nuclear Receptor Hepatocyte Nuclear Factor 4α1 | Full Text | References | PDF (1.5 MB)
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Article
AnCF, the CCAAT Binding Complex of Aspergillus nidulans, Is Essential for the Formation of a DNase I-Hypersensitive Site in the 5′ Region of the amdS Gene
Frank M. Narendja, Meryl A. Davis & Michael J. Hynes
Pages: 6523-6531
Published online: 28 Mar 2023
AbstractforAnCF, the CCAAT Binding Complex of Aspergillus nidulans, Is Essential for the Formation of a DNase I-Hypersensitive Site in the 5′ Region of the amdS Gene | Full Text | References | PDF (594.8 KB)
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Article
The ADA Complex Is a Distinct Histone Acetyltransferase Complex in Saccharomyces cerevisiae
Anton Eberharter, David E. Sterner, David Schieltz, Ahmed Hassan, John R. Yates III, Shelley L. Berger & Jerry L. Workman
Pages: 6621-6631
Published online: 28 Mar 2023
AbstractforThe ADA Complex Is a Distinct Histone Acetyltransferase Complex in Saccharomyces cerevisiae | Full Text | References | PDF (2.1 MB)
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Article
RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins
Albert Lai, Joseph M. Lee, Wen-Ming Yang, James A. DeCaprio, William G. Kaelin Jr., Edward Seto & Philip E. Branton
Pages: 6632-6641
Published online: 28 Mar 2023
AbstractforRBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins | Full Text | References | PDF (2.1 MB)
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Article
The CCR4 and CAF1 Proteins of the CCR4-NOT Complex Are Physically and Functionally Separated from NOT2, NOT4, and NOT5
Yongli Bai, Christopher Salvadore, Yueh-Chin Chiang, Martine A. Collart, Hai-Yan Liu & Clyde L. Denis
Pages: 6642-6651
Published online: 28 Mar 2023
AbstractforThe CCR4 and CAF1 Proteins of the CCR4-NOT Complex Are Physically and Functionally Separated from NOT2, NOT4, and NOT5 | Full Text | References | PDF (1.7 MB)
  • 49 Views
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Article
A Transcriptional Switch in the Expression of Yeast Tricarboxylic Acid Cycle Genes in Response to a Reduction or Loss of Respiratory Function
Zhengchang Liu & Ronald A. Butow
Pages: 6720-6728
Published online: 28 Mar 2023
AbstractforA Transcriptional Switch in the Expression of Yeast Tricarboxylic Acid Cycle Genes in Response to a Reduction or Loss of Respiratory Function | Full Text | References | PDF (2.8 MB)
  • 76 Views
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Article
Regulation of Cell Cycle Transcription Factor Swi4 through Auto-Inhibition of DNA Binding
Kristin Baetz & Brenda Andrews
Pages: 6729-6741
Published online: 28 Mar 2023
AbstractforRegulation of Cell Cycle Transcription Factor Swi4 through Auto-Inhibition of DNA Binding | Full Text | References | PDF (1.4 MB)
  • 15 Views
  • 30 CrossRef citations
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Article
Cytomegalovirus IE2 Protein Stimulates Interleukin 1β Gene Transcription via Tethering to Spi-1/PU.1
Nawarat Wara-aswapati, Zhiyong Yang, Wayne R. Waterman, Yoshinobu Koyama, Sotirios Tetradis, Bob K. Choy, Andrew C. Webb & Philip E. Auron
Pages: 6803-6814
Published online: 28 Mar 2023
AbstractforCytomegalovirus IE2 Protein Stimulates Interleukin 1β Gene Transcription via Tethering to Spi-1/PU.1 | Full Text | References | PDF (483 KB)
  • 8 Views
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Article
Cooperation of Six and Eya in Activation of Their Target Genes through Nuclear Translocation of Eya
Hiromi Ohto, Sayaka Kamada, Kenji Tago, Shin-Ichi Tominaga, Hidenori Ozaki, Shigeru Sato & Kiyoshi Kawakami
Pages: 6815-6824
Published online: 28 Mar 2023
AbstractforCooperation of Six and Eya in Activation of Their Target Genes through Nuclear Translocation of Eya | Full Text | References | PDF (1.3 MB)
  • 24 Views
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Article
An Autoregulatory Loop Controlling CYP1A1 Gene Expression: Role of H2O2and NFI
Yannick Morel, Nicolas Mermod & Robert Barouki
Pages: 6825-6832
Published online: 28 Mar 2023
AbstractforAn Autoregulatory Loop Controlling CYP1A1 Gene Expression: Role of H2O2and NFI | Full Text | References | PDF (246.4 KB)
  • 29 Views
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Article
hnRNP U Inhibits Carboxy-Terminal Domain Phosphorylation by TFIIH and Represses RNA Polymerase II Elongation
Myung K. Kim & Vera M. Nikodem
Pages: 6833-6844
Published online: 28 Mar 2023
AbstractforhnRNP U Inhibits Carboxy-Terminal Domain Phosphorylation by TFIIH and Represses RNA Polymerase II Elongation | Full Text | References | PDF (1.4 MB)
  • 74 Views
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Article
Multifunctional Role of the Pitx2 Homeodomain Protein C-Terminal Tail
Brad A. Amendt, Lillian B. Sutherland & Andrew F. Russo
Pages: 7001-7010
Published online: 28 Mar 2023
AbstractforMultifunctional Role of the Pitx2 Homeodomain Protein C-Terminal Tail | Full Text | References | PDF (1.7 MB)
  • 14 Views
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Article
Interacting Regions in Stat3 and c-Jun That Participate in Cooperative Transcriptional Activation
Xiaokui Zhang, Melissa H. Wrzeszczynska, Curt M. Horvath & James E. Darnell Jr.
Pages: 7138-7146
Published online: 28 Mar 2023
AbstractforInteracting Regions in Stat3 and c-Jun That Participate in Cooperative Transcriptional Activation | Full Text | References | PDF (1.5 MB)
  • 44 Views
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Article
Physical and Functional Interactions between Cellular Retinoic Acid Binding Protein II and the Retinoic Acid-Dependent Nuclear Complex
Laurent Delva, Jean-Noël Bastie, Cécile Rochette-Egly, Radhia Kraïba, Nicole Balitrand, Gilles Despouy, Pierre Chambon & Christine Chomienne
Pages: 7158-7167
Published online: 28 Mar 2023
AbstractforPhysical and Functional Interactions between Cellular Retinoic Acid Binding Protein II and the Retinoic Acid-Dependent Nuclear Complex | Full Text | References | PDF (1.8 MB)
  • 26 Views
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Article
NRIF3 Is a Novel Coactivator Mediating Functional Specificity of Nuclear Hormone Receptors
Dangsheng Li, Vandana Desai-Yajnik, Eric Lo, Matthieu Schapira, Ruben Abagyan & Herbert H. Samuels
Pages: 7191-7202
Published online: 28 Mar 2023
AbstractforNRIF3 Is a Novel Coactivator Mediating Functional Specificity of Nuclear Hormone Receptors | Full Text | References | PDF (481.1 KB)
  • 6 Views
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Article
Targeted Disruption of Mouse Yin Yang 1 Transcription Factor Results in Peri-Implantation Lethality
Mary E. Donohoe, Xiaolin Zhang, Lynda McGinnis, John Biggers, En Li & Yang Shi
Pages: 7237-7244
Published online: 28 Mar 2023
AbstractforTargeted Disruption of Mouse Yin Yang 1 Transcription Factor Results in Peri-Implantation Lethality | Full Text | References | PDF (1.9 MB)
  • 51 Views
  • 280 CrossRef citations
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Transcriptional Repression of Stat6-Dependent Interleukin-4-Induced Genes by BCL-6: Specific Regulation of Iɛ Transcription and Immunoglobulin E Switching
Miera B. Harris, Chih-Chao Chang, Michael T. Berton, Nika N. Danial, Jandong Zhang, Denise Kuehner, Bihui H. Ye, Marina Kvatyuk, Pier Paolo Pandolfi, Giorgio Cattoretti, Riccardo Dalla-Favera & Paul B. Rothman
Pages: 7264-7275
Published online: 28 Mar 2023
AbstractforTranscriptional Repression of Stat6-Dependent Interleukin-4-Induced Genes by BCL-6: Specific Regulation of Iɛ Transcription and Immunoglobulin E Switching | Full Text | References | PDF (1.6 MB)
  • 45 Views
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Dna Dynamics and Chromosome Structure

Article
The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2
Vassilis Aidinis, Tiziana Bonaldi, Monica Beltrame, Sandro Santagata, Marco E. Bianchi & Eugenia Spanopoulou
Pages: 6532-6542
Published online: 28 Mar 2023
AbstractforThe RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2 | Full Text | References | PDF (1.7 MB)
  • 16 Views
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Article
DOT4 Links Silencing and Cell Growth in Saccharomyces cerevisiae
Alon Kahana & Daniel E. Gottschling
Pages: 6608-6620
Published online: 28 Mar 2023
AbstractforDOT4 Links Silencing and Cell Growth in Saccharomyces cerevisiae | Full Text | References | PDF (2.7 MB)
  • 20 Views
  • 49 CrossRef citations
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Article
Regulated Formation of Extrachromosomal Circular DNA Molecules during Development in Xenopus laevis
Sarit Cohen, Sophie Menut & Marcel Méchali
Pages: 6682-6689
Published online: 28 Mar 2023
AbstractforRegulated Formation of Extrachromosomal Circular DNA Molecules during Development in Xenopus laevis | Full Text | References | PDF (3.7 MB)
  • 36 Views
  • 37 CrossRef citations
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Article
Roles of Cell Division and Gene Transcription in the Methylation of CpG Islands
Christina M. Bender, Mark L. Gonzalgo, Felicidad A. Gonzales, Carvell T. Nguyen, Keith D. Robertson & Peter A. Jones
Pages: 6690-6698
Published online: 28 Mar 2023
AbstractforRoles of Cell Division and Gene Transcription in the Methylation of CpG Islands | Full Text | References | PDF (732.7 KB)
  • 35 Views
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Article
Clustered Adenine/Thymine Stretches Are Essential for Function of a Fission Yeast Replication Origin
Yukiko Okuno, Hiroyasu Satoh, Mariko Sekiguchi & Hisao Masukata
Pages: 6699-6709
Published online: 28 Mar 2023
AbstractforClustered Adenine/Thymine Stretches Are Essential for Function of a Fission Yeast Replication Origin | Full Text | References | PDF (3.1 MB)
  • 7 Views
  • 74 CrossRef citations
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Article
The Essential Functions of Human Rad51 Are Independent of ATP Hydrolysis
Ciaran Morrison, Akira Shinohara, Eiichiro Sonoda, Yuko Yamaguchi-Iwai, Minoru Takata, Ralph R. Weichselbaum & Shunichi Takeda
Pages: 6891-6897
Published online: 28 Mar 2023
AbstractforThe Essential Functions of Human Rad51 Are Independent of ATP Hydrolysis | Full Text | References | PDF (591.6 KB)
  • 72 Views
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Article
Sperm Chromatin Decondensation by Template Activating Factor I through Direct Interaction with Basic Proteins
Ken Matsumoto, Kyosuke Nagata, Mary Miyaji-Yamaguchi, Akihiko Kikuchi & Masafumi Tsujimoto
Pages: 6940-6952
Published online: 28 Mar 2023
AbstractforSperm Chromatin Decondensation by Template Activating Factor I through Direct Interaction with Basic Proteins | Full Text | References | PDF (3.9 MB)
  • 27 Views
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Article
Association of Fission Yeast Orp1 and Mcm6 Proteins with Chromosomal Replication Origins
Yuya Ogawa, Tatsuro Takahashi & Hisao Masukata
Pages: 7228-7236
Published online: 28 Mar 2023
AbstractforAssociation of Fission Yeast Orp1 and Mcm6 Proteins with Chromosomal Replication Origins | Full Text | References | PDF (2 MB)
  • 21 Views
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Cell and Organelle Structure and Assembly

Article
Mutations Affecting a Yeast Mitochondrial Inner Membrane Protein, Pnt1p, Block Export of a Mitochondrially Synthesized Fusion Protein from the Matrix
Shichuan He & Thomas D. Fox
Pages: 6598-6607
Published online: 28 Mar 2023
AbstractforMutations Affecting a Yeast Mitochondrial Inner Membrane Protein, Pnt1p, Block Export of a Mitochondrially Synthesized Fusion Protein from the Matrix | Full Text | References | PDF (2.4 MB)
  • 9 Views
  • 45 CrossRef citations
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Article
Mutations Altering the Predicted Secondary Structure of a Chloroplast 5′ Untranslated Region Affect Its Physical and Biochemical Properties as Well as Its Ability To Promote Translation of Reporter mRNAs Both in the Chlamydomonas reinhardtii Chloroplast and in Escherichia coli
David C. Fargo, John E. Boynton & Nicholas W. Gillham
Pages: 6980-6990
Published online: 28 Mar 2023
AbstractforMutations Altering the Predicted Secondary Structure of a Chloroplast 5′ Untranslated Region Affect Its Physical and Biochemical Properties as Well as Its Ability To Promote Translation of Reporter mRNAs Both in the Chlamydomonas reinhardtii Chloroplast and in Escherichia coli | Full Text | References | PDF (499.5 KB)
  • 11 Views
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Article
The Net Repressor Is Regulated by Nuclear Export in Response to Anisomycin, UV, and Heat Shock
Catherine Ducret, Sauveur-Michel Maira, Andrée Dierich & Bohdan Wasylyk
Pages: 7076-7087
Published online: 28 Mar 2023
AbstractforThe Net Repressor Is Regulated by Nuclear Export in Response to Anisomycin, UV, and Heat Shock | Full Text | References | PDF (2.4 MB)
  • 8 Views
  • 57 CrossRef citations
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Author's Correction

Correction
Tumor-Specific PAX3-FKHR Transcription Factor, but Not PAX3, Activates the Platelet-Derived Growth Factor Alpha Receptor
Page: 7287
Published online: 28 Mar 2023
CitationforTumor-Specific PAX3-FKHR Transcription Factor, but Not PAX3, Activates the Platelet-Derived Growth Factor Alpha Receptor | Full Text | PDF (21.5 KB)
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Free Access
Correction
The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain
Page: 7287
Published online: 28 Mar 2023
CitationforThe Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain | Full Text | PDF (21.5 KB)
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