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Molecular and Cellular Biology Volume 19, 1999 - Issue 10
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Cell Growth and Development

The Oncogenic 70Z Cbl Mutation Blocks the Phosphotyrosine Binding Domain-Dependent Negative Regulation of ZAP-70 by c-Cbl in Jurkat T Cells

Jeroen E. M. van LeeuwenLaboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland20892Correspondence[email protected]
,
Paul K. PaikLaboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland20892
&
Lawrence E. SamelsonLaboratory of Cellular and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland20892
Pages 6652-6664 | Received 04 Feb 1999, Accepted 25 Jun 1999, Published online: 28 Mar 2023

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Lakshmi Balagopalan, Valarie A. Barr, Connie L. Sommers, Mira Barda-Saad, Amrita Goyal, Matthew S. Isakowitz & Lawrence E. Samelson. (2007) c-Cbl-Mediated Regulation of LAT-Nucleated Signaling Complexes. Molecular and Cellular Biology 27:24, pages 8622-8636.
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Michael P. Loreto, Donna M. Berry & C. Jane McGlade. (2002) Functional Cooperation between c-Cbl and Src-Like Adaptor Protein 2 in the Negative Regulation of T-Cell Receptor Signaling. Molecular and Cellular Biology 22:12, pages 4241-4255.
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Saijun Fan, Yong Xian Ma, Min Gao, Ren-Qi Yuan, Qinghui Meng, Itzhak D. Goldberg & Eliot M. Rosen. (2001) The Multisubstrate Adapter Gab1 Regulates Hepatocyte Growth Factor (Scatter Factor)–c-Met Signaling for Cell Survival and DNA Repair. Molecular and Cellular Biology 21:15, pages 4968-4984.
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Articles from other publishers (17)

Enkhtsetseg PurevLynn NeffWilliam C. HorneRoland Baron. (2009) c-Cbl and Cbl-b Act Redundantly to Protect Osteoclasts from Apoptosis and to Displace HDAC6 from β-Tubulin, Stabilizing Microtubules and Podosomes. Molecular Biology of the Cell 20:18, pages 4021-4030.
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Carola Reindl, Hilmar Quentmeier, Konstantin Petropoulos, Philipp A. Greif, Tobias Benthaus, Bob Argiropoulos, Gudrun Mellert, Sridhar Vempati, Justus Duyster, Christian Buske, Stefan K. Bohlander, Keith R. Humphries, Wolfgang Hiddemann & Karsten Spiekermann. (2009) CBL Exon 8/9 Mutants Activate the FLT3 Pathway and Cluster in Core Binding Factor/11q Deletion Acute Myeloid Leukemia/Myelodysplastic Syndrome Subtypes. Clinical Cancer Research 15:7, pages 2238-2247.
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Yingxiao Wang, Joann Chang, Yi-Chen Li, Yi-Shuan Li, John Y.-J. Shyy & Shu Chien. (2004) Shear stress and VEGF activate IKK via the Flk-1/Cbl/Akt signaling pathway. American Journal of Physiology-Heart and Circulatory Physiology 286:2, pages H685-H692.
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Laurie J Graham, Maria-Concetta Verí, Karen E DeBell, Cristiana Noviello, Rashmi Rawat, Sandy Jen, Ezio Bonvini & Barbara Rellahan. (2003) 70Z/3 Cbl induces PLCγ1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism. Oncogene 22:16, pages 2493-2503.
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Konstantina Alexandropoulos, Laura T. Donlin, Luzhou Xing & Adam G. Regelmann. (2003) Sin: good or bad? A T lymphocyte perspective. Immunological Reviews 192:1, pages 181-195.
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Andrew Freywald, Nigel Sharfe & Chaim M. Roifman. (2002) The Kinase-null EphB6 Receptor Undergoes Transphosphorylation in a Complex with EphB1. Journal of Biological Chemistry 277:6, pages 3823-3828.
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Alexander Y Tsygankov, Anjali M Teckchandani, Elena A Feshchenko & Gayathri Swaminathan. (2001) Beyond the RING: CBL proteins as multivalent adapters. Oncogene 20:44, pages 6382-6402.
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Masahiro Yokouchi, Takeshi Kondo, Archana Sanjay, Adam Houghton, Akihiko Yoshimura, Seturo Komiya, Hui Zhang & Roland Baron. (2001) Src-catalyzed Phosphorylation of c-Cbl Leads to the Interdependent Ubiquitination of Both Proteins. Journal of Biological Chemistry 276:37, pages 35185-35193.
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Pin Ling, Christian F. Meyer, Lisa P. Redmond, Jr-Wen Shui, Beckley Davis, Robert R. Rich, Mickey C.-T. Hu, Ronald L. Wange & Tse-Hua Tan. (2001) Involvement of Hematopoietic Progenitor Kinase 1 in T Cell Receptor Signaling. Journal of Biological Chemistry 276:22, pages 18908-18914.
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Christine B. F. Thien & Wallace Y. Langdon. (2001) Cbl: many adaptations to regulate protein tyrosine kinases. Nature Reviews Molecular Cell Biology 2:4, pages 294-307.
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Thomas Harder. 2001. 45 92 .
Jennifer A. Epler, Rugao Liu, Heekyoung Chung, Nadine C. Ottoson & Yoji Shimizu. (2000) Regulation of β1 Integrin-Mediated Adhesion by T Cell Receptor Signaling Involves ZAP-70 but Differs from Signaling Events That Regulate Transcriptional Activity. The Journal of Immunology 165:9, pages 4941-4949.
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Heinz Jacobs. (2000) TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function. Seminars in Immunology 12:5, pages 487-502.
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Sansana Sawasdikosol, Joanne C. Pratt, Wuyi Meng, Michael J. Eck & Steven J. Burakoff. (2000) Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1471:1, pages M1-M12.
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Anne Astier, Marie-Claude Trescol-Biémont, Olga Azocar, Barbara Lamouille & Chantal Rabourdin-Combe. (2000) Cutting Edge: CD46, a New Costimulatory Molecule for T Cells, That Induces p120CBL and LAT Phosphorylation. The Journal of Immunology 164:12, pages 6091-6095.
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Peggy S Myung, Nancy J Boerthe & Gary A Koretzky. (2000) Adapter proteins in lymphocyte antigen-receptor signaling. Current Opinion in Immunology 12:3, pages 256-266.
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Laurie J. Graham, Karen E. DeBell, Maria-Concetta Verı́, Bogdan Stoica, Howard Mostowski, Ezio Bonvini & Barbara Rellahan. (2000) Differential effects of Cbl and 70Z/3 Cbl on T cell receptor-induced phospholipase Cγ-1 activity. FEBS Letters 470:3, pages 273-280.
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