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Molecular and Cellular Biology Volume 19, 1999 - Issue 10
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Cell Growth and Development

Concerted Regulation of Wild-Type p53 Nuclear Accumulation and Activation by S100B and Calcium-Dependent Protein Kinase C

Christian ScottoDépartement de Biologie Moléculaire et Structurale du CEA, DBMS-BRCE INSERM Unité244, 38054Grenoble Cedex 9, France
,
Christian DelphinDépartement de Biologie Moléculaire et Structurale du CEA, DBMS-BRCE INSERM Unité244, 38054Grenoble Cedex 9, France
,
Jean Christophe DeloulmeDépartement de Biologie Moléculaire et Structurale du CEA, DBMS-BRCE INSERM Unité244, 38054Grenoble Cedex 9, France
&
Jacques BaudierDépartement de Biologie Moléculaire et Structurale du CEA, DBMS-BRCE INSERM Unité244, 38054Grenoble Cedex 9, FranceCorrespondence[email protected]
Pages 7168-7180 | Received 09 Feb 1999, Accepted 10 Jun 1999, Published online: 28 Mar 2023

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Alan An Jung Wei, Claudio Iacobucci, Wiebke Schultze, Christian H. Ihling, Christian Arlt & Andrea Sinz. (2022) Different Oligomeric States of the Tumor Suppressor p53 Show Identical Binding Behavior towards the S100β Homodimer. ChemBioChem 23:11.
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Revansiddha H. Katte, Ruey-Hwang Chou & Chin Yu. (2020) Pentamidine inhibit S100A4 - p53 interaction and decreases cell proliferation activity. Archives of Biochemistry and Biophysics 691, pages 108442.
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Jacques Baudier, Jean Christophe Deloulme & Gary S. Shaw. (2020) The Zn 2+ and Ca 2+ ‐binding S100B and S100A1 proteins: beyond the myths . Biological Reviews 95:3, pages 738-758.
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Jacques Baudier & Benoit J Gentil. (2020) The S100B Protein and Partners in Adipocyte Response to Cold Stress and Adaptive Thermogenesis: Facts, Hypotheses, and Perspectives. Biomolecules 10:6, pages 843.
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E. Semik-Gurgul, T. Ząbek, A. Fornal, M. Wnuk, K. Pawlina-Tyszko, A. Gurgul, J. Klukowska-Rötzler, C. Koch, K. Mählmann & M. Bugno-Poniewierska. (2018) DNA methylation patterns of the S100A14, POU2F3 and SFN genes in equine sarcoid tissues. Research in Veterinary Science 119, pages 302-307.
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Eivind Valen Egeland, Kjetil Boye, Solveig J. Pettersen, Mads H. Haugen, Tove Øyjord, Lene Malerød, Kjersti Flatmark & Gunhild M. Mælandsmo. (2015) Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes. Clinical & Experimental Metastasis 32:8, pages 755-767.
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Gurpreet Kaur, Jennifer D. Ly-Huynh & David A. Jans. (2014) Intracellular calcium levels can regulate Importin-dependent nuclear import. Biochemical and Biophysical Research Communications 450:1, pages 812-817.
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Bolin Qin, Kiran S. Panickar & Richard A. Anderson. (2014) Cinnamon polyphenols regulate S100β, sirtuins, and neuroactive proteins in rat C6 glioma cells. Nutrition 30:2, pages 210-217.
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Tara M. DeSilva, Natalia S. Borenstein, Joseph J. Volpe, Hannah C. Kinney & Paul A. Rosenberg. (2012) Expression of EAAT2 in neurons and protoplasmic astrocytes during human cortical development. Journal of Comparative Neurology 520:17, pages 3912-3932.
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Manel Joaquin, Albert Gubern, Daniel González-Nuñez, E Josué Ruiz, Isabel Ferreiro, Eulalia de Nadal, Angel R Nebreda & Francesc Posas. (2012) The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress. The EMBO Journal 31:13, pages 2952-2964.
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Jie Lu, Gewei Lian, Hui Zhou, Giuseppe Esposito, Luca Steardo, Laurent C. Delli-Bovi, Jonathan L. Hecht, Q. Richard Lu & Volney Sheen. (2012) OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors. Human Molecular Genetics 21:10, pages 2330-2340.
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Dipak Sapkota, Daniela Elena Costea, Magnus Blø, Ove Bruland, James B. Lorens, Endre N. Vasstrand & Salah O. Ibrahim. (2012) S100A14 inhibits proliferation of oral carcinoma derived cells through G1-arrest. Oral Oncology 48:3, pages 219-225.
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Hayato Tamai, Koichi MiyakeHiroki Yamaguchi, Miyuki Takatori, Kazuo Dan, Koiti Inokuchi & Takashi Shimada. (2012) AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice. Blood 119:1, pages 64-71.
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H Tamai, K Miyake, H Yamaguchi, M Takatori, K Dan, K Inokuchi & T Shimada. (2011) Resistance of MLL–AFF1-positive acute lymphoblastic leukemia to tumor necrosis factor-alpha is mediated by S100A6 upregulation. Blood Cancer Journal 1:11, pages e38-e38.
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Gisle Berge & Gunhild M. Mælandsmo. (2010) Evaluation of potential interactions between the metastasis-associated protein S100A4 and the tumor suppressor protein p53. Amino Acids 41:4, pages 863-873.
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M. R. Fernandez-Fernandez & B. Sot. (2010) The relevance of protein-protein interactions for p53 function: the CPE contribution. Protein Engineering Design and Selection 24:1-2, pages 41-51.
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Danna B. Zimmer & David J. Weber. (2010) The Calcium-Dependent Interaction of S100B with Its Protein Targets. Cardiovascular Psychiatry and Neurology 2010, pages 1-17.
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Jan van Dieck, Jenifer K. Lum, Daniel P. Teufel & Alan R. Fersht. (2010) S100 proteins interact with the N-terminal domain of MDM2. FEBS Letters 584:15, pages 3269-3274.
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Jing Lin, Qingyuan Yang, Paul T. Wilder, France Carrier & David J. Weber. (2010) The Calcium-binding Protein S100B Down-regulates p53 and Apoptosis in Malignant Melanoma. Journal of Biological Chemistry 285:35, pages 27487-27498.
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J van Dieck, T Brandt, D P Teufel, D B Veprintsev, A C Joerger & A R Fersht. (2010) Molecular basis of S100 proteins interacting with the p53 homologs p63 and p73. Oncogene 29:14, pages 2024-2035.
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Jan van Dieck, Daniel P. Teufel, Agnes M. Jaulent, Maria R. Fernandez-Fernandez, Trevor J. Rutherford, Alexandra Wyslouch-Cieszynska & Alan R. Fersht. (2009) Posttranslational Modifications Affect the Interaction of S100 Proteins with Tumor Suppressor p53. Journal of Molecular Biology 394:5, pages 922-930.
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Rosario Donato, Guglielmo Sorci, Francesca Riuzzi, Cataldo Arcuri, Roberta Bianchi, Flora Brozzi, Claudia Tubaro & Ileana Giambanco. (2009) S100B's double life: Intracellular regulator and extracellular signal. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1793:6, pages 1008-1022.
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Jan van Dieck, Maria R. Fernandez-Fernandez, Dmitry B. Veprintsev & Alan R. Fersht. (2009) Modulation of the Oligomerization State of p53 by Differential Binding of Proteins of the S100 Family to p53 Monomers and Tetramers. Journal of Biological Chemistry 284:20, pages 13804-13811.
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Łukasz P. Słomnicki, Barbara Nawrot & Wiesława Leśniak. (2009) S100A6 binds p53 and affects its activity. The International Journal of Biochemistry & Cell Biology 41:4, pages 784-790.
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Maria Rosario Fernandez-Fernandez, Trevor J. Rutherford & Alan R. Fersht. (2008) Members of the S100 family bind p53 in two distinct ways. Protein Science 17:10, pages 1663-1670.
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Yvonne Arendt, Anusarka Bhaumik, Rebecca Del Conte, Claudio Luchinat, Mattia Mori & Marco Porcu. (2007) Fragment Docking to S100 Proteins Reveals a Wide Diversity of Weak Interaction Sites. ChemMedChem 2:11, pages 1648-1654.
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Ryszard Jeczen, Danuta Skomra, Marek Cybulski, Regine Schneider-Stock, Wiktor Szewczuk, Albert Roessner, Tomasz Rechberger & Andrzej Semczuk. (2007) P53/MDM2 overexpression in metastatic endometrial cancer: correlation with clinicopathological features and patient outcome. Clinical & Experimental Metastasis 24:7, pages 503-511.
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Artur Gieldon, Mattia Mori & Rebecca Del Conte. (2007) Theoretical study on binding of S100B protein. Journal of Molecular Modeling 13:11, pages 1123-1131.
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Andrea Mueller, Beat W. Schäfer, Stefano Ferrari, Mirjam Weibel, Miro Makek, Matthias Höchli & Claus W. Heizmann. (2005) The Calcium-binding Protein S100A2 Interacts with p53 and Modulates Its Transcriptional Activity. Journal of Biological Chemistry 280:32, pages 29186-29193.
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Eric Meyer, Jean-Yves Vollmer, Raymonde Bovey & Ivan Stamenkovic. (2005) Matrix Metalloproteinases 9 and 10 Inhibit Protein Kinase C–Potentiated, p53-Mediated Apoptosis. Cancer Research 65:10, pages 4261-4272.
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Maria Rosario Fernandez-Fernandez, Dmitry B. Veprintsev & Alan R. Fersht. (2005) Proteins of the S100 family regulate the oligomerization of p53 tumor suppressor. Proceedings of the National Academy of Sciences 102:13, pages 4735-4740.
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J.N. Tsoporis, A. Marks, A. Haddad, D. O'Hanlon, S. Jolly & T.G. Parker. (2005) S100A6 is a negative regulator of the induction of cardiac genes by trophic stimuli in cultured rat myocytes. Experimental Cell Research 303:2, pages 471-481.
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Jean Christophe Deloulme, Eric Raponi, Benoît Jean Gentil, Nathalie Bertacchi, Alexander Marks, Gérard Labourdette & Jacques Baudier. (2004) Nuclear expression of S100B in oligodendrocyte progenitor cells correlates with differentiation toward the oligodendroglial lineage and modulates oligodendrocytes maturation. Molecular and Cellular Neuroscience 27:4, pages 453-465.
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Houman Vaghefi & Kenneth E Neet. (2004) Deacetylation of p53 after nerve growth factor treatment in PC12 cells as a post-translational modification mechanism of neurotrophin-induced tumor suppressor activation. Oncogene 23:49, pages 8078-8087.
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Daniel Satgé, Annie J. Sasco, Henri Pujol & Marie-Odile Rethoré. (2001) Les cancers mammaires des femmes trisomiques 21. Bulletin de l'Académie Nationale de Médecine 185:7, pages 1239-1254.
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Gabriela E. Davey, Petra Murmann & Claus W. Heizmann. (2001) Intracellular Ca2+ and Zn2+ Levels Regulate the Alternative Cell Density-dependent Secretion of S100B in Human Glioblastoma Cells. Journal of Biological Chemistry 276:33, pages 30819-30826.
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Alison L. Allan, Chris Albanese, Richard G. Pestell & Jonathan LaMarre. (2001) Activating Transcription Factor 3 Induces DNA Synthesis and Expression of Cyclin D1 in Hepatocytes. Journal of Biological Chemistry 276:29, pages 27272-27280.
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Benoit J. Gentil, Christian Delphin, Gaëlh Ouengue Mbele, Jean Christophe Deloulme, Myriam Ferro, Jérôme Garin & Jacques Baudier. (2001) The Giant Protein AHNAK Is a Specific Target for the Calcium- and Zinc-binding S100B Protein. Journal of Biological Chemistry 276:26, pages 23253-23261.
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Mariam Grigorian, Susanne Andresen, Eugene Tulchinsky, Marina Kriajevska, Charlotte Carlberg, Charlotte Kruse, Martin Cohn, Noona Ambartsumian, Annette Christensen, Galina Selivanova & Eugene Lukanidin. (2001) Tumor Suppressor p53 Protein Is a New Target for the Metastasis-associated Mts1/S100A4 Protein. Journal of Biological Chemistry 276:25, pages 22699-22708.
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Shun-Hsin Liang & Michael F. Clarke. (2001) Regulation of p53 localization. European Journal of Biochemistry 268:10, pages 2779-2783.
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Jean Christophe Deloulme, Nicole Assard, Gaëlh Ouengue Mbele, Carole Mangin, Ryozo Kuwano & Jacques Baudier. (2000) S100A6 and S100A11 Are Specific Targets of the Calcium- and Zinc-binding S100B Protein in Vivo. Journal of Biological Chemistry 275:45, pages 35302-35310.
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Theresia B. Stradal, Heinz Troxler, Claus W. Heizmann & Mario Gimona. (2000) Mapping the Zinc Ligands of S100A2 by Site-directed Mutagenesis. Journal of Biological Chemistry 275:18, pages 13219-13227.
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David J. Weber, Richard R. Rustandi, France Carrier & Danna B. Zimmer. 2000. Calcium: The Molecular Basis of Calcium Action in Biology and Medicine. Calcium: The Molecular Basis of Calcium Action in Biology and Medicine 521 539 .

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