Citations (561)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (43)
Orlando Morales-Tarré, Ramiro Alonso-Bastida, Bolivar Arcos-Encarnación, Leonor Pérez-Martínez & Sergio Encarnación-Guevara. (2021) Protein lysine acetylation and its role in different human pathologies: a proteomic approach. Expert Review of Proteomics 18:11, pages 949-975.
Read now
Read now
Anbu Karani Adikesavan, Sudipan Karmakar, Patricia Pardo, Liguo Wang, Shuang Liu, Wei Li & Carolyn L. Smith. (2014) Activation of p53 Transcriptional Activity by SMRT: a Histone Deacetylase 3-Independent Function of a Transcriptional Corepressor. Molecular and Cellular Biology 34:7, pages 1246-1261.
Read now
Read now
Ian M. Love, Pedja Sekaric, Dingding Shi, Steven R. Grossman & Elliot J. Androphy. (2012) The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3. Cell Cycle 11:13, pages 2458-2466.
Read now
Read now
Hong Wu & Roger P. Leng. (2011) UBE4B, a ubiquitin chain assembly factor, is required for MDM2-mediated p53 polyubiquitination and degradation. Cell Cycle 10:12, pages 1912-1915.
Read now
Read now
Abhinav K. Jain & Michelle Craig Barton. (2010) Making sense of ubiquitin ligases that regulate p53. Cancer Biology & Therapy 10:7, pages 665-672.
Read now
Read now
Kenji Yoshimochi, Hiroaki Daitoku & Akiyoshi Fukamizu. (2010) PCAF represses transactivation function of FOXO1 in an acetyltransferase-independent manner. Journal of Receptors and Signal Transduction 30:1, pages 43-49.
Read now
Read now
Karen A Boehme & Christine Blattner. (2009) Regulation of p53 - insights into a complex process. Critical Reviews in Biochemistry and Molecular Biology 44:6, pages 367-392.
Read now
Read now
William Coley, Kylene Kehn-Hall, Rachel Van Duyne & Fatah Kashanchi. (2009) Novel HIV-1 therapeutics through targeting altered host cell pathways. Expert Opinion on Biological Therapy 9:11, pages 1369-1382.
Read now
Read now
Sama F Sleiman, Manuela Basso, Lata Mahishi, Alan P Kozikowski, Mary E Donohoe, Brett Langley & Rajiv R Ratan. (2009) Putting the ‘HAT’ back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions. Expert Opinion on Investigational Drugs 18:5, pages 573-584.
Read now
Read now
Melissa J. MacPherson, Linda G. Beatty, Wenjing Zhou, Minjie Du & Paul D. Sadowski. (2009) The CTCF Insulator Protein Is Posttranslationally Modified by SUMO. Molecular and Cellular Biology 29:3, pages 714-725.
Read now
Read now
Masayoshi Iizuka, Olga F. Sarmento, Takao Sekiya, Heidi Scrable, C. David Allis & M. Mitchell Smith. (2008) Hbo1 Links p53-Dependent Stress Signaling to DNA Replication Licensing. Molecular and Cellular Biology 28:1, pages 140-153.
Read now
Read now
Ran Xiao, Ye Sun, Jian-Hua Ding, Shengrong Lin, Dave W. Rose, Michael G. Rosenfeld, Xiang-Dong Fu & Xue Li. (2007) Splicing Regulator SC35 Is Essential for Genomic Stability and Cell Proliferation during Mammalian Organogenesis. Molecular and Cellular Biology 27:15, pages 5393-5402.
Read now
Read now
Ping Bu, Yvonne A. Evrard, Guillermina Lozano & Sharon Y. R. Dent. (2007) Loss of Gcn5 Acetyltransferase Activity Leads to Neural Tube Closure Defects and Exencephaly in Mouse Embryos. Molecular and Cellular Biology 27:9, pages 3405-3416.
Read now
Read now
Xiaodan Su, Chen Ren & Michael A Freitas. (2007) Mass spectrometry-based strategies for characterization of histones and their post-translational modifications. Expert Review of Proteomics 4:2, pages 211-225.
Read now
Read now
Connie Chao, Zhiqun Wu, Sharlyn J. Mazur, Helena Borges, Matteo Rossi, Tongxiang Lin, Jean Y. J. Wang, Carl W. Anderson, Ettore Appella & Yang Xu. (2006) Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage. Molecular and Cellular Biology 26:18, pages 6859-6869.
Read now
Read now
Eun Joo Chung, Min-Jung Lee, Sunmin Lee & Jane B Trepel. (2006) Assays for pharmacodynamic analysis of histone deacetylase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 2:2, pages 213-230.
Read now
Read now
Ying Zhao, Shaoli Lu, Lipeng Wu, Guolin Chai, Haiying Wang, Yingqi Chen, Jia Sun, Yu Yu, Wen Zhou, Quanhui Zheng, Mian Wu, Gregory A. Otterson & Wei-Guo Zhu. (2006) Acetylation of p53 at Lysine 373/382 by the Histone Deacetylase Inhibitor Depsipeptide Induces Expression of p21Waf1/Cip1. Molecular and Cellular Biology 26:7, pages 2782-2790.
Read now
Read now
Øystein Bruserud, Camilla Stapnes, Karl Johan Tronstad, Anita Ryningen, Nina Ånensen & Bjørn Tore Gjertsen. (2006) Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML. Expert Opinion on Therapeutic Targets 10:1, pages 51-68.
Read now
Read now
Jin Ming Dai, Dao Chun Sun, Ru Xian Lin, Jing Yang, Shaoke Lou & Sheng Qi Wang. (2006) Microarray analysis of differentially expressed genes in mouse bone marrow tissues after ionizing radiation. International Journal of Radiation Biology 82:7, pages 511-521.
Read now
Read now
Wei-Yi Chen, Li-Jung Juan & Bon-chu Chung. (2005) SF-1 (Nuclear Receptor 5A1) Activity Is Activated by Cyclic AMP via p300-Mediated Recruitment to Active Foci, Acetylation, and Increased DNA Binding. Molecular and Cellular Biology 25:23, pages 10442-10453.
Read now
Read now
Lin-Feng Chen, Samuel A. Williams, Yajun Mu, Hiroyasu Nakano, James M. Duerr, Leonard Buckbinder & Warner C. Greene. (2005) NF-κB RelA Phosphorylation Regulates RelA Acetylation. Molecular and Cellular Biology 25:18, pages 7966-7975.
Read now
Read now
Lijin Feng, Tongxiang Lin, Hiroaki Uranishi, Wei Gu & Yang Xu. (2005) Functional Analysis of the Roles of Posttranslational Modifications at the p53 C Terminus in Regulating p53 Stability and Activity. Molecular and Cellular Biology 25:13, pages 5389-5395.
Read now
Read now
Carol Imbriano, Aymone Gurtner, Fabienne Cocchiarella, Silvia Di Agostino, Valentina Basile, Monica Gostissa, Matthias Dobbelstein, Giannino Del Sal, Giulia Piaggio & Roberto Mantovani. (2005) Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters. Molecular and Cellular Biology 25:9, pages 3737-3751.
Read now
Read now
Anastasia A. Gridasova & R. William Henry. (2005) The p53 Tumor Suppressor Protein Represses Human snRNA Gene Transcription by RNA Polymerases II and III Independently of Sequence-Specific DNA Binding. Molecular and Cellular Biology 25:8, pages 3247-3260.
Read now
Read now
Maofu Fu, Mahadev Rao, Chenguang Wang, Toshiyuki Sakamaki, Jian Wang, Dolores Di Vizio, Xueping Zhang, Chris Albanese, Steven Balk, Chawnshang Chang, Saijun Fan, Eliot Rosen, Jorma J. Palvimo, Olli A. Jänne, Selen Muratoglu, Maria Laura Avantaggiati & Richard G. Pestell. (2003) Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth. Molecular and Cellular Biology 23:23, pages 8563-8575.
Read now
Read now
Apollina Goel & Ralf Janknecht. (2003) Acetylation-Mediated Transcriptional Activation of the ETS Protein ER81 by p300, P/CAF, and HER2/Neu. Molecular and Cellular Biology 23:17, pages 6243-6254.
Read now
Read now
Gerda Lagger, Angelika Doetzlhofer, Bernd Schuettengruber, Eva Haidweger, Elisabeth Simboeck, Julia Tischler, Susanna Chiocca, Guntram Suske, Hans Rotheneder, Erhard Wintersberger & Christian Seiser. (2003) The Tumor Suppressor p53 and Histone Deacetylase 1 Are Antagonistic Regulators of the Cyclin-Dependent Kinase Inhibitor p21/WAF1/CIP1 Gene. Molecular and Cellular Biology 23:8, pages 2669-2679.
Read now
Read now
An-Yong Xie, Vladimir P. Bermudez & William R. Folk. (2002) Stimulation of DNA Replication from the Polyomavirus Origin by PCAF and GCN5 Acetyltransferases: Acetylation of Large T Antigen. Molecular and Cellular Biology 22:22, pages 7907-7918.
Read now
Read now
Penny G. Ard, Chandrima Chatterjee, Sudeesha Kunjibettu, Leon R. Adside, Lisa E. Gralinski & Steven B. McMahon. (2002) Transcriptional Regulation of the mdm2 Oncogene by p53 Requires TRRAP Acetyltransferase Complexes. Molecular and Cellular Biology 22:16, pages 5650-5661.
Read now
Read now
Wei Hong, Alexander Y. Kim, Sokun Ky, Carrie Rakowski, Sang-Beom Seo, Debabrata Chakravarti, Michael Atchison & Gerd A. Blobel. (2002) Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1. Molecular and Cellular Biology 22:11, pages 3729-3743.
Read now
Read now
Maofu Fu, Chenguang Wang, Jian Wang, Xueping Zhang, Toshiyuki Sakamaki, Y. G. Yeung, Chawnshang Chang, Torsten Hopp, Suzanne A. W. Fuqua, Ellis Jaffray, Ron T. Hay, Jorma J. Palvimo, Olli A. Jänne & Richard G. Pestell. (2002) Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function. Molecular and Cellular Biology 22:10, pages 3373-3388.
Read now
Read now
Dong
Hwa Yang, Byung
KM Rhee, Tae
Hee Yim, Hye
Jin Lee & Jungho Kim. (2002) DNA damage‐inducible phosphorylation of p53 at Ser20 is required for p53 stabilization. Korean Journal of Biological Sciences 6:3, pages 263-269.
Read now
Read now
Matthew G. Guenther, Orr Barak & Mitchell A. Lazar. (2001) The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3. Molecular and Cellular Biology 21:18, pages 6091-6101.
Read now
Read now
Ya-Li Yao, Wen-Ming Yang & Edward Seto. (2001) Regulation of Transcription Factor YY1 by Acetylation and Deacetylation. Molecular and Cellular Biology 21:17, pages 5979-5991.
Read now
Read now
Yu-Cai Peng, Felix Kuo, David E. Breiding, Yu-Fang Wang, Claire P. Mansur & Elliot J. Androphy. (2001) AMF1 (GPS2) Modulates p53 Transactivation. Molecular and Cellular Biology 21:17, pages 5913-5924.
Read now
Read now
Suzanne T. Szak, Deborah Mays & Jennifer A. Pietenpol. (2001) Kinetics of p53 Binding to Promoter Sites In Vivo. Molecular and Cellular Biology 21:10, pages 3375-3386.
Read now
Read now
Charalambos Spilianakis, Joseph Papamatheakis & Androniki Kretsovali. (2000) Acetylation by PCAF Enhances CIITA Nuclear Accumulation and Transactivation of Major Histocompatibility Complex Class II Genes. Molecular and Cellular Biology 20:22, pages 8489-8498.
Read now
Read now
Sridhar Mani, Chenguang Wang, Kongming Wu, Richard Francis & Richard Pestell. (2000) Cyclin-dependent kinase inhibitors: novel anticancer agents. Expert Opinion on Investigational Drugs 9:8, pages 1849-1870.
Read now
Read now
Jorge A. Iñiguez-Lluhí & David Pearce. (2000) A Common Motif within the Negative Regulatory Regions of Multiple Factors Inhibits Their Transcriptional Synergy. Molecular and Cellular Biology 20:16, pages 6040-6050.
Read now
Read now
Yue Liu, April L. Colosimo, Xiang-Jiao Yang & Daiqing Liao. (2000) Adenovirus E1B 55-Kilodalton Oncoprotein Inhibits p53 Acetylation by PCAF. Molecular and Cellular Biology 20:15, pages 5540-5553.
Read now
Read now
Xiaoya Zeng, Xiaorong Li, Ashley Miller, Zhimin Yuan, Wuchao Yuan, Roland P. S. Kwok, Richard Goodman & Hua Lu. (2000) The N-Terminal Domain of p73 Interacts with the CH1 Domain of p300/CREB Binding Protein and Mediates Transcriptional Activation and Apoptosis. Molecular and Cellular Biology 20:4, pages 1299-1310.
Read now
Read now
Ying Nie, Heng-Hong Li, Craig M. Bula & Xuan Liu. (2000) Stimulation of p53 DNA Binding by c-Abl Requires the p53 C Terminus and Tetramerization. Molecular and Cellular Biology 20:3, pages 741-748.
Read now
Read now
Hua Jiang, Hanxin Lu, R. Louis Schiltz, Cynthia A. Pise-Masison, Vasily V. Ogryzko, Yoshihiro Nakatani & John N. Brady. (1999) PCAF Interacts with Tax and Stimulates Tax Transactivation in a Histone Acetyltransferase-Independent Manner. Molecular and Cellular Biology 19:12, pages 8136-8145.
Read now
Read now
Articles from other publishers (518)
Avik Ghosh, Poushali Chakraborty & Debabrata Biswas. (2023) Fine tuning of the transcription juggernaut: A sweet and sour saga of acetylation and ubiquitination. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1866:3, pages 194944.
Crossref
Crossref
Jialin Yao, Lu Liu, Qingxiang Sun & Xiaofei Shen. (2023) Direct cellular targets and anticancer mechanisms of the natural product oridonin. MedComm – Future Medicine 2:1.
Crossref
Crossref
Olivia A. Fraser, Sophia M. Dewing, Emery T. Usher, Christy George & Scott A. Showalter. (2023) A direct nuclear magnetic resonance method to investigate lysine acetylation of intrinsically disordered proteins. Frontiers in Molecular Biosciences 9.
Crossref
Crossref
Christopher L. Brooks. 2023. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology
327
335
.
Shuang Shang, Jing Liu & Fang Hua. (2022) Protein acylation: mechanisms, biological functions and therapeutic targets. Signal Transduction and Targeted Therapy 7:1.
Crossref
Crossref
Shinjinee Sengupta, Shaikh Maryam Ghufran, Aqsa Khan, Subhrajit Biswas & Susanta Roychoudhury. (2022) Transition of amyloid/mutant p53 from tumor suppressor to an oncogene and therapeutic approaches to ameliorate metastasis and cancer stemness. Cancer Cell International 22:1.
Crossref
Crossref
Alexander S. Krois, Sangho Park, Maria A. Martinez-Yamout, H. Jane Dyson & Peter E. Wright. (2022) Mapping Interactions of the Intrinsically Disordered C-Terminal Regions of Tetrameric p53 by Segmental Isotope Labeling and NMR. Biochemistry 61:23, pages 2709-2719.
Crossref
Crossref
Alessandra Amendolare, Flaviana Marzano, Vittoria Petruzzella, Rosa Anna Vacca, Luisa Guerrini, Graziano Pesole, Elisabetta Sbisà & Apollonia Tullo. (2022) The Underestimated Role of the p53 Pathway in Renal Cancer. Cancers 14:23, pages 5733.
Crossref
Crossref
Pascal Vong, Hakim Ouled-Haddou & Loïc Garçon. (2022) Histone Deacetylases Function in the Control of Early Hematopoiesis and Erythropoiesis. International Journal of Molecular Sciences 23:17, pages 9790.
Crossref
Crossref
Mayra A. Marques, Guilherme C. de Andrade, Jerson L. Silva & Guilherme A. P. de Oliveira. (2022) Protein of a thousand faces: The tumor-suppressive and oncogenic responses of p53. Frontiers in Molecular Biosciences 9.
Crossref
Crossref
Laura E. Schultz‐Rogers, Michelle L. Thayer, Sekhar Kambakam, Wesley A. Wierson, Jordan A. Helmer, Mark D. Wishman, Kristen A. Wall, Jessica L. Greig, Jaimie L. Forsman, Kavya Puchhalapalli, Siddharth Nair, Trevor J. Weiss, Jon M. Luiken, Patrick R. Blackburn, Stephen C. Ekker, Marcel Kool & Maura McGrail. (2022) Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis. Developmental Dynamics 251:8, pages 1267-1290.
Crossref
Crossref
Manvi Sharma & Trygve O. Tollefsbol. (2022) Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition. Experimental Cell Research 416:1, pages 113160.
Crossref
Crossref
Olga A. Sukocheva, Elena Lukina, Markus Friedemann, Mario Menschikowski, Albert Hagelgans & Gjumrakch Aliev. (2022) The crucial role of epigenetic regulation in breast cancer anti-estrogen resistance: Current findings and future perspectives. Seminars in Cancer Biology 82, pages 35-59.
Crossref
Crossref
Johnny M Tkach, Reuben Philip, Amit Sharma, Jonathan Strecker, Daniel Durocher & Laurence Pelletier. (2022) Global cellular response to chemical perturbation of PLK4 activity and abnormal centrosome number. eLife 11.
Crossref
Crossref
Varun Sasidharan Nair, Maud Heredia, Janneke Samsom & Jochen Huehn. (2022) Impact of gut microenvironment on epigenetic signatures of intestinal T helper cell subsets. Immunology Letters 246, pages 27-36.
Crossref
Crossref
Zhangchuan Xia, Ning Kon, Alyssa P. Gu, Omid Tavana & Wei Gu. (2022) Deciphering the acetylation code of p53 in transcription regulation and tumor suppression. Oncogene 41:22, pages 3039-3050.
Crossref
Crossref
Nicholas A. Lehning & Brad E. Morrison. (2022) Nonhistone Lysine Methylation as a Protein Degradation Signal. Journal of Chemistry 2022, pages 1-7.
Crossref
Crossref
Lev Zavileyskiy & Victoria Bunik. (2022) Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes. Biomolecules 12:2, pages 327.
Crossref
Crossref
Melina Mitsiogianni, Ioannis Anestopoulos, Sotiris Kyriakou, Dimitrios T. Trafalis, Rodrigo Franco, Aglaia Pappa & Mihalis I. Panayiotidis. (2021) Benzyl and phenethyl isothiocyanates as promising epigenetic drug compounds by modulating histone acetylation and methylation marks in malignant melanoma. Investigational New Drugs 39:6, pages 1460-1468.
Crossref
Crossref
Wesley W. Wang, Li-Yun Chen, Jacob M. Wozniak, Appaso M. Jadhav, Hayden Anderson, Taylor E. Malone & Christopher G. Parker. (2021) Targeted Protein Acetylation in Cells Using Heterobifunctional Molecules. Journal of the American Chemical Society 143:40, pages 16700-16708.
Crossref
Crossref
Siqi Wen, Jiajia Li, Jingru Yang, Biao Li, Na Li & Xianquan Zhan. (2021) Quantitative Acetylomics Revealed Acetylation-Mediated Molecular Pathway Network Changes in Human Nonfunctional Pituitary Neuroendocrine Tumors. Frontiers in Endocrinology 12.
Crossref
Crossref
Yongwoon Lim, Anna Jeong, Duk-Hwa Kwon, Yeong-Un Lee, Young-Kook Kim, Youngkeun Ahn, Taewon Kook, Woo-Jin Park & Hyun Kook. (2021) P300/CBP-Associated Factor Activates Cardiac Fibroblasts by SMAD2 Acetylation. International Journal of Molecular Sciences 22:18, pages 9944.
Crossref
Crossref
Bin Deng, Pu Xu, Bingyu Zhang, Qing Luo & Guanbin Song. (2021) COX2 Enhances Neovascularization of Inflammatory Tenocytes Through the HIF-1α/VEGFA/PDGFB Pathway. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Ashley Francois, Alessandro Canella, Lynn M. Marcho & Matthew S. Stratton. (2021) Protein acetylation in cardiac aging. Journal of Molecular and Cellular Cardiology 157, pages 90-97.
Crossref
Crossref
Sandra Nitsch, Lara Zorro Shahidian & Robert Schneider. (2021) Histone acylations and chromatin dynamics: concepts, challenges, and links to metabolism. EMBO reports 22:7.
Crossref
Crossref
M. Janaki Ramaiah, Anjana Devi Tangutur & Rajasekhar Reddy Manyam. (2021) Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy. Life Sciences 277, pages 119504.
Crossref
Crossref
J. P. Jose Merlin, H. P. Vasantha Rupasinghe, Graham Dellaire & Kieran Murphy. (2021) Role of Dietary Antioxidants in p53-Mediated Cancer Chemoprevention and Tumor Suppression. Oxidative Medicine and Cellular Longevity 2021, pages 1-18.
Crossref
Crossref
Halima Alsamri, Hussain El Hasasna, Bincy Baby, Aysha Alneyadi, Yusra Al Dhaheri, Mohammed Akli Ayoub, Ali H. Eid, Ranjit Vijayan & Rabah Iratni. (2021) Carnosol Is a Novel Inhibitor of p300 Acetyltransferase in Breast Cancer. Frontiers in Oncology 11.
Crossref
Crossref
Yong Jun Choi, Jongsung Lee, Sang Hoon Ha, Han Ki Lee, Heui Min Lim, Seon‐Hak Yu, Chang Min Lee, Myeong Jin Nam, Yung‐Hun Yang, Kyungmoon Park, Youn Soo Choi, Kyu Yun Jang & See‐Hyoung Park. (2020)
6,
8‐Diprenylorobol
induces apoptosis in human colon cancer cells via activation of intracellular reactive oxygen species and p53
. Environmental Toxicology 36:5, pages 914-925.
Crossref
Crossref
Sarah F. Giardina, Elena Valdambrini, J. David Warren & Francis Barany. (2021) PROTACs: Promising Approaches for Epigenetic Strategies to Overcome Drug Resistance. Current Cancer Drug Targets 21:4, pages 306-325.
Crossref
Crossref
Elena Kunadis, Eleftheria Lakiotaki, Penelope Korkolopoulou & Christina Piperi. (2021) Targeting post-translational histone modifying enzymes in glioblastoma. Pharmacology & Therapeutics 220, pages 107721.
Crossref
Crossref
Anne H. Moxley & David Reisman. (2020) Context is key: Understanding the regulation, functional control, and activities of the p53 tumour suppressor. Cell Biochemistry and Function 39:2, pages 235-247.
Crossref
Crossref
Evangelia Koutelou, Aimee T. Farria & Sharon Y.R. Dent. (2021) Complex functions of Gcn5 and Pcaf in development and disease. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1864:2, pages 194609.
Crossref
Crossref
Michael Downey. (2021) Non-histone protein acetylation by the evolutionarily conserved GCN5 and PCAF acetyltransferases. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1864:2, pages 194608.
Crossref
Crossref
Melina Mitsiogianni, Dimitrios T. Trafalis, Rodrigo Franco, Vasilis Zoumpourlis, Aglaia Pappa & Mihalis I. Panayiotidis. (2020) Sulforaphane and iberin are potent epigenetic modulators of histone acetylation and methylation in malignant melanoma. European Journal of Nutrition 60:1, pages 147-158.
Crossref
Crossref
Sara Martire, Jennifer Nguyen, Aishwarya Sundaresan & Laura A. Banaszynski. (2020) Differential contribution of p300 and CBP to regulatory element acetylation in mESCs. BMC Molecular and Cell Biology 21:1.
Crossref
Crossref
Marta Falcicchio, Jake A. Ward, Salvador Macip & Richard G. Doveston. (2020) Regulation of p53 by the 14-3-3 protein interaction network: new opportunities for drug discovery in cancer. Cell Death Discovery 6:1.
Crossref
Crossref
Ying Xiong, Mingming Zhang & Yingxia Li. (2020) Recent Advances in the Development of CBP/p300 Bromodomain Inhibitors. Current Medicinal Chemistry 27:33, pages 5583-5598.
Crossref
Crossref
Morgan A Sammons, Thuy-Ai T Nguyen, Simon S McDade & Martin Fischer. (2020) Tumor suppressor p53: from engaging DNA to target gene regulation. Nucleic Acids Research 48:16, pages 8848-8869.
Crossref
Crossref
Seo-Hyun Choi, Su-Yeon Cho, Jiyang Song & Man-Wook Hur. (2020) KLHL4, a novel p53 target gene, inhibits cell proliferation by activating p21. Biochemical and Biophysical Research Communications 530:3, pages 588-596.
Crossref
Crossref
Nasir Haider, Previn Dutt, Bert van de Kooij, Jason Ho, Luis Palomero, Miquel Angel Pujana, Michael Yaffe & Vuk Stambolic. (2020) NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. Oncogene 39:30, pages 5252-5266.
Crossref
Crossref
Ya-Fei Lu, Xiao-Peng Xu, Xiao-Peng Lu, Qian Zhu, Ge Liu, Yan-Tao Bao, He Wen, Ying-Lu Li, Wei Gu & Wei-Guo Zhu. (2020) SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle. Oncogene 39:24, pages 4650-4665.
Crossref
Crossref
Linda Anna Michelle Kulka, Pia-Victoria Fangmann, Diana Panfilova & Heidi Olzscha. (2020) Impact of HDAC Inhibitors on Protein Quality Control Systems: Consequences for Precision Medicine in Malignant Disease. Frontiers in Cell and Developmental Biology 8.
Crossref
Crossref
Sabrina Wilde, Nina Queisser & Andreas Sutter. (2020) Image analysis of mechanistic protein biomarkers for the characterization of genotoxicants: Aneugens, clastogens, and reactive oxygen species inducers. Environmental and Molecular Mutagenesis 61:5, pages 534-550.
Crossref
Crossref
Yue Wu, Xue Wang, Feifei Xu, Lu Zhang, Tianjiao Wang, Xueli Fu, Tianzhi Jin, Weiying Zhang & Lihong Ye. (2020) The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth. Nucleic Acids Research 48:9, pages 4858-4876.
Crossref
Crossref
J. Novak, B. Zamostna, V. Vopalensky, M. Buryskova, L. Burysek, D. Doleckova & M. Pospisek. (2020) Interleukin-1α associates with the tumor suppressor p53 following DNA damage. Scientific Reports 10:1.
Crossref
Crossref
Tomas Venit, Khairunnisa Semesta, Sannia Farrukh, Martin Endara-Coll, Robert Havalda, Pavel Hozak & Piergiorgio Percipalle. (2020) Nuclear myosin 1 activates p21 gene transcription in response to DNA damage through a chromatin-based mechanism. Communications Biology 3:1.
Crossref
Crossref
Yaxi Yang, Rukang Zhang, Zhaojun Li, Lianghe Mei, Shili Wan, Hong Ding, Zhifeng Chen, Jing Xing, Huijin Feng, Jie Han, Hualiang Jiang, Mingyue Zheng, Cheng Luo & Bing Zhou. (2020) Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors. Journal of Medicinal Chemistry 63:3, pages 1337-1360.
Crossref
Crossref
Li‐Ting Wang, Kwei‐Yan Liu, Wen‐Yih Jeng, Cheng‐Ming Chiang, Chee‐Yin Chai, Shyh‐Shin Chiou, Ming‐Shyang Huang, Kazunari K Yokoyama, Shen‐Nien Wang, Shau‐Ku Huang & Shih‐Hsien Hsu. (2020)
PCAF
‐mediated acetylation of
ISX
recruits
BRD
4 to promote epithelial‐mesenchymal transition
. EMBO reports 21:2.
Crossref
Crossref
James AL Brown. (2020) Patent spotlight: small-molecule lysine acetyltransferase inhibitors (KATi). Pharmaceutical Patent Analyst 9:1, pages 17-28.
Crossref
Crossref
Jérôme Archambeau, Alice Blondel & Rémy Pedeux. (2019) Focus-ING on DNA Integrity: Implication of ING Proteins in Cell Cycle Regulation and DNA Repair Modulation. Cancers 12:1, pages 58.
Crossref
Crossref
Toshiaki Tanaka, Yasukazu Hozumi, Alberto M. Martelli, Mitsuyoshi Iino & Kaoru Goto. (2019) Nucleosome assembly proteins NAP1L1 and NAP1L4 modulate p53 acetylation to regulate cell fate. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:12, pages 118560.
Crossref
Crossref
Qun Li, Qiongyu Hao, Wei Cao, Jieqing Li, Ke Wu, Yahya ElshimaliDonghui Zhu, Qiao-Hong Chen, Guanglin ChenJonathan R. PollackJay Vadgama & Yong Wu. (2019) PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer. Science Advances 5:10.
Crossref
Crossref
Mengyuan Huang, Jiangkun Huang, Yongcheng Zheng & Qiu Sun. (2019) Histone acetyltransferase inhibitors: An overview in synthesis, structure-activity relationship and molecular mechanism. European Journal of Medicinal Chemistry 178, pages 259-286.
Crossref
Crossref
Seo-Hyun Choi, Dong-In Koh, Su-Yeon Cho, Min-Kyeong Kim, Kyung-Sup Kim & Man-Wook Hur. (2019) Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis. Journal of Biological Chemistry 294:35, pages 12957-12974.
Crossref
Crossref
Dan Levy. (2019) Lysine methylation signaling of non-histone proteins in the nucleus. Cellular and Molecular Life Sciences 76:15, pages 2873-2883.
Crossref
Crossref
Zimam Mahmud, Ana R. Gomes, Hee Jin Lee, Sathid Aimjongjun, Yannasittha Jiramongkol, Shang Yao, Stefania Zona, Glowi Alasiri, Gyungyub Gong, Ernesto Yagüe & Eric W.-F. Lam. (2019) EP300 and SIRT1/6 Co-Regulate Lapatinib Sensitivity Via Modulating FOXO3-Acetylation and Activity in Breast Cancer. Cancers 11:8, pages 1067.
Crossref
Crossref
Yanqing Liu, Omid Tavana & Wei Gu. (2019) p53 modifications: exquisite decorations of the powerful guardian. Journal of Molecular Cell Biology 11:7, pages 564-577.
Crossref
Crossref
Tong Liu, Xiang Wang, Wenquan Hu, Zhi Fang, Ying Jin, Xuedong Fang & Qing Robert Miao. (2019) Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil. Neoplasia 21:6, pages 557-570.
Crossref
Crossref
Maria Mrakovcic, Johannes Kleinheinz & Leopold F. Fröhlich. (2019) p53 at the Crossroads between Different Types of HDAC Inhibitor-Mediated Cancer Cell Death. International Journal of Molecular Sciences 20:10, pages 2415.
Crossref
Crossref
Yujie Liu, Chunrong Bao, Liqing Wang, Rongxiang Han, Ulf H. Beier, Tatiana Akimova, Philip A. Cole, Sharon Y. R. Dent & Wayne W. Hancock. (2019) Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells. Cancers 11:4, pages 554.
Crossref
Crossref
Yang Li, Zhuoyi Wang, Yuchen Chen, Robert B. Petersen, Ling Zheng & Kun Huang. (2019) Salvation of the fallen angel: Reactivating mutant p53. British Journal of Pharmacology 176:7, pages 817-831.
Crossref
Crossref
Leandros Boukas, James M. Havrilla, Peter F. Hickey, Aaron R. Quinlan, Hans T. Bjornsson & Kasper D. Hansen. (2019) Coexpression patterns define epigenetic regulators associated with neurological dysfunction. Genome Research 29:4, pages 532-542.
Crossref
Crossref
Magdalena Dabrowska, Marek Skoneczny, Lukasz Uram & Wojciech Rode. (2019) Methotrexate-induced senescence of human colon cancer cells depends on p53 acetylation, but not genomic aberrations. Anti-Cancer Drugs 30:4, pages 374-382.
Crossref
Crossref
Kanaga Sabapathy & David P Lane. (2019) Understanding p53 functions through p53 antibodies. Journal of Molecular Cell Biology 11:4, pages 317-329.
Crossref
Crossref
Rui Zhou, Yi Yang, So-Yeon Park, Young-Woo Seo, Sang-Chul Jung, Kyung Keun Kim, Kwonseop Kim & Hangun Kim. (2019) p300/CBP-associated factor promotes autophagic degradation of δ-catenin through acetylation and decreases prostate cancer tumorigenicity. Scientific Reports 9:1.
Crossref
Crossref
Matteo Savoia, Chiara Cencioni, Mattia Mori, Sandra Atlante, Germana Zaccagnini, Paolo Devanna, Lucia Di Marcotullio, Bruno Botta, Fabio Martelli, Andreas M. Zeiher, Alfredo Pontecorvi, Antonella Farsetti, Francesco Spallotta & Carlo Gaetano. (2018) P300/CBP‐associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation. The FASEB Journal 33:3, pages 4107-4123.
Crossref
Crossref
Emma Bondy-ChorneyAlix DenoncourtYuka SaiMichael Downey. (2019) Nonhistone targets of KAT2A and KAT2B implicated in cancer biology. Biochemistry and Cell Biology 97:1, pages 30-45.
Crossref
Crossref
Ji-Hye Kim, Dahee Kim, Suk Joon Cho, Kwan-Young Jung, Jong-Hoon Kim, Jun Mi Lee, Hee Jung Jung & Kwang Rok Kim. (2019) Identification of a novel SIRT7 inhibitor as anticancer drug candidate. Biochemical and Biophysical Research Communications 508:2, pages 451-457.
Crossref
Crossref
Tongxin Wang, Weilei Yao, Yafei Shao, Ruilong Zheng & Feiruo Huang. (2018) PCAF fine-tunes hepatic metabolic syndrome, inflammatory disease, and cancer. Journal of Cellular and Molecular Medicine 22:12, pages 5787-5800.
Crossref
Crossref
Kosuke Funato, Tomoatsu Hayashi, Kanae Echizen, Lumi Negishi, Naomi Shimizu, Ryo Koyama‐Nasu, Yukiko Nasu‐Nishimura, Yasuyuki Morishita, Viviane Tabar, Tomoki Todo, Yasushi Ino, Akitake Mukasa, Nobuhito Saito & Tetsu Akiyama. (2018)
SIRT
2‐mediated inactivation of p73 is required for glioblastoma tumorigenicity
. EMBO reports 19:11.
Crossref
Crossref
Yuhong Pan, Pengfei Li, Renyong Jia, Mingshu Wang, Zhongqiong Yin & Anchun Cheng. (2018) Regulation of Apoptosis During Porcine Circovirus Type 2 Infection. Frontiers in Microbiology 9.
Crossref
Crossref
Sony Pandey, Jennifer Bourn & Maria Cekanova. (2018) Mutations of p53 decrease sensitivity to the anthracycline treatments in bladder cancer cells. Oncotarget 9:47, pages 28514-28531.
Crossref
Crossref
Stephanie Kaypee, Smitha Asoka Sahadevan, Shilpa Patil, Piya Ghosh, Neeladri Sekhar Roy, Siddhartha Roy & Tapas K. Kundu. (2018) Mutant and Wild-Type Tumor Suppressor p53 Induces p300 Autoacetylation. iScience 4, pages 260-272.
Crossref
Crossref
Sara Gonçalves, Julie Patat, Maria Clara Guida, Noelle Lachaussée, Christelle Arrondel, Martin Helmstädter, Olivia Boyer, Olivier Gribouval, Marie-Claire Gubler, Geraldine Mollet, Marlène Rio, Marina Charbit, Christine Bole-Feysot, Patrick Nitschke, Tobias B. Huber, Patricia G. Wheeler, Devon Haynes, Jane Juusola, Thierry Billette de Villemeur, Caroline Nava, Alexandra Afenjar, Boris Keren, Rolf Bodmer, Corinne Antignac & Matias Simons. (2018) A homozygous KAT2B variant modulates the clinical phenotype of ADD3 deficiency in humans and flies. PLOS Genetics 14:5, pages e1007386.
Crossref
Crossref
Dai Hatakeyama, Masaki Shoji, Seiya Yamayoshi, Rina Yoh, Naho Ohmi, Shiori Takenaka, Ayaka Saitoh, Yumie Arakaki, Aki Masuda, Tsugunori Komatsu, Rina Nagano, Masahiro Nakano, Takeshi Noda, Yoshihiro Kawaoka & Takashi Kuzuhara. (2018) Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5. Journal of Biological Chemistry 293:19, pages 7126-7138.
Crossref
Crossref
Daniella Brasacchio, Rita A. Busuttil, Tahereh Noori, Ricky W. Johnstone, Alex Boussioutas & Joseph A. Trapani. (2018) Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer. Cell Death & Disease 9:5.
Crossref
Crossref
Józefa Węsierska-Gądek. (2018) Targeting p53 as a promising therapeutic option for cancer by re-activating the wt or mutant p53’s tumor suppression. Future Medicinal Chemistry 10:7, pages 755-777.
Crossref
Crossref
Di Ding, Lin-Lin Chen, Ying-Zhen Zhai, Chen-Jian Hou, Li-Li Tao, Shu-Han Lu, Jian Wu & Xiu-Ping Liu. (2018) Trichostatin A inhibits the activation of Hepatic stellate cells by Increasing C/EBP-α Acetylation in vivo and in vitro. Scientific Reports 8:1.
Crossref
Crossref
Fu-Long Li, Jin-Ping Liu, Ruo-Xuan Bao, GuoQuan Yan, Xu Feng, Yan-Ping Xu, Yi-Ping Sun, Weili Yan, Zhi-Qiang Ling, Yue Xiong, Kun-Liang Guan & Hai-Xin Yuan. (2018) Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis. Nature Communications 9:1.
Crossref
Crossref
Ashish Kumar & Sudhir Chandna. (2018) Evidence for a radiation-responsive ‘p53 gateway’ contributing significantly to the radioresistance of lepidopteran insect cells. Scientific Reports 8:1.
Crossref
Crossref
Janaki Parameswaran & Barbara Burtness. 2018. Molecular Determinants of Head and Neck Cancer. Molecular Determinants of Head and Neck Cancer
249
274
.
Song-Yi Park, Sophors Phorl, Suna Jung, Korm Sovannarith, Se-in Lee, Solhee Noh, Miae Han, Rema Naskar, Jae-Young Kim, Yun-Jaie Choi & Joo-Yong Lee. (2017) HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation. Biochemical and Biophysical Research Communications 494:1-2, pages 51-56.
Crossref
Crossref
Tatiana Souslova, Kim Mirédin, Anne M. Millar & Paul R. Albert. (2016) Recruitment by the Repressor Freud-1 of Histone Deacetylase-Brg1 Chromatin Remodeling Complexes to Strengthen HTR1A Gene Repression. Molecular Neurobiology 54:10, pages 8263-8277.
Crossref
Crossref
Jong-Ryoul Choi, Seo-Young Lee, Ki Soon Shin, Cheol Yong Choi & Shin Jung Kang. (2017) p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function. Scientific Reports 7:1.
Crossref
Crossref
Bu-Nam Jeon, Jae-Hyeon Yoon, Dohyun Han, Min-Kyeong Kim, Youngsoo Kim, Seo-Hyun Choi, Jiyang Song, Kyung-Sup Kim, Kunhong Kim & Man-Wook Hur. (2017) ZNF509S1 downregulates PUMA by inhibiting p53K382 acetylation and p53-DNA binding. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:9, pages 962-972.
Crossref
Crossref
Shunsheng Zheng, Xin Yu Koh, Hui Chin Goh, Siti Aishah B. Rahmat, Le-Ann Hwang & David P. Lane. (2017) Inhibiting p53 Acetylation Reduces Cancer Chemotoxicity. Cancer Research 77:16, pages 4342-4354.
Crossref
Crossref
Meimei Zhao, Rui Geng, Xiang Guo, Ruoshi Yuan, Xiao Zhou, Yanyan Zhong, Yanfei Huo, Mei Zhou, Qinjian Shen, Yinglu Li, Weiguo Zhu & Jiadong Wang. (2017) PCAF/GCN5-Mediated Acetylation of RPA1 Promotes Nucleotide Excision Repair. Cell Reports 20:9, pages 1997-2009.
Crossref
Crossref
Shaoyun Chen, Hairong Liang, Hui Yang, Kairu Zhou, Longmei Xu, Jiaxian Liu, Bei Lai, Li Song, Hao Luo, Jianming Peng, Zhidong Liu, Yongmei Xiao, Wen Chen & Huanwen Tang. (2017) LincRNa-p21: function and mechanism in cancer. Medical Oncology 34:5.
Crossref
Crossref
William K. Songock, Seong-man Kim & Jason M. Bodily. (2017) The human papillomavirus E7 oncoprotein as a regulator of transcription. Virus Research 231, pages 56-75.
Crossref
Crossref
Yoshitaka Sunami, Marito Araki, Shin Kan, Akihiro Ito, Yumi Hironaka, Misa Imai, Soji Morishita, Akimichi Ohsaka & Norio Komatsu. (2017) Histone Acetyltransferase p300/CREB-binding Protein-associated Factor (PCAF) Is Required for All-trans-retinoic Acid-induced Granulocytic Differentiation in Leukemia Cells. Journal of Biological Chemistry 292:7, pages 2815-2829.
Crossref
Crossref
Derrick J. Morton, Divya Patel, Jugal Joshi, Aisha Hunt, Ashley E. Knowell & Jaideep Chaudhary. (2016) ID4 regulates transcriptional activity of wild type and mutant p53 via K373 acetylation. Oncotarget 8:2, pages 2536-2549.
Crossref
Crossref
Jeovanis Gil, Alberto Ramírez-Torres & Sergio Encarnación-Guevara. (2017) Lysine acetylation and cancer: A proteomics perspective. Journal of Proteomics 150, pages 297-309.
Crossref
Crossref
Hannah Wapenaar & Frank J. Dekker. (2016) Histone acetyltransferases: challenges in targeting bi-substrate enzymes. Clinical Epigenetics 8:1.
Crossref
Crossref
Vered Domankevich, Yarden Opatowsky, Assaf Malik, Abraham B. Korol, Zeev Frenkel, Irena Manov, Aaron Avivi & Imad Shams. (2016) Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax. BMC Evolutionary Biology 16:1.
Crossref
Crossref
Adrian Drazic, Line M. Myklebust, Rasmus Ree & Thomas Arnesen. (2016) The world of protein acetylation. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1864:10, pages 1372-1401.
Crossref
Crossref
Fade Gong, Li-Ya Chiu & Kyle M. Miller. (2016) Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer. PLOS Genetics 12:9, pages e1006272.
Crossref
Crossref
Hye-Jeong Choi, Seongran Kwon & Dae-Won Kim. (2016) A post-translational modification cascade employing HDAC9-PIASy-RNF4 axis regulates chondrocyte hypertrophy by modulating Nkx3.2 protein stability. Cellular Signalling 28:9, pages 1336-1348.
Crossref
Crossref
Ping Zhang, Yunsong Liu, Chanyuan Jin, Min Zhang, Longwei Lv, Xiao Zhang, Hao Liu & Yongsheng Zhou. (2016) Histone H3K9 Acetyltransferase PCAF Is Essential for Osteogenic Differentiation Through Bone Morphogenetic Protein Signaling and May Be Involved in Osteoporosis. Stem Cells 34:9, pages 2332-2341.
Crossref
Crossref
Igor F. Tsigelny, Valentina L. Kouznetsova, Nathan Lian & Santosh Kesari. (2016) Molecular mechanisms of OLIG2 transcription factor in brain cancer. Oncotarget 7:33, pages 53074-53101.
Crossref
Crossref
Morgan A Sammons, Jiajun Zhu & Shelley L Berger. (2016) A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription. G3 Genes|Genomes|Genetics 6:8, pages 2671-2678.
Crossref
Crossref
Abu Salah Ud-Din, Alexandra Tikhomirova & Anna Roujeinikova. (2016) Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT). International Journal of Molecular Sciences 17:7, pages 1018.
Crossref
Crossref
Stephanie Kaypee, Deepthi Sudarshan, Muthu K. Shanmugam, Debanjan Mukherjee, Gautam Sethi & Tapas K. Kundu. (2016) Aberrant lysine acetylation in tumorigenesis: Implications in the development of therapeutics. Pharmacology & Therapeutics 162, pages 98-119.
Crossref
Crossref
Qing Li, Zhikui Liu, Meng Xu, Yumo Xue, Bowen Yao, Changwei Dou, Yuli Jia, Yufeng Wang, Kangsheng Tu, Xin Zheng & Yingmin Yao. (2016) PCAF inhibits hepatocellular carcinoma metastasis by inhibition of epithelial-mesenchymal transition by targeting Gli-1. Cancer Letters 375:1, pages 190-198.
Crossref
Crossref
Andreas S. Madsen, Christian Andersen, Mohammad Daoud, Kristin A. Anderson, Jonas S. Laursen, Saswati Chakladar, Frank K. Huynh, Ana R. Colaço, Donald S. Backos, Peter Fristrup, Matthew D. Hirschey & Christian A. Olsen. (2016) Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH. Journal of Biological Chemistry 291:13, pages 7128-7141.
Crossref
Crossref
Sathish Kumar Mungamuri, Rui F. Qiao, Shen Yao, James J. Manfredi, Wei Gu & Stuart A. Aaronson. (2016) USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation. Cell Reports 14:11, pages 2528-2537.
Crossref
Crossref
Tzu-Chin Wu, Yi-Chin Lin, Hsiao-Ling Chen, Pei-Ru Huang, Shang-Yu Liu & Shu-Lan Yeh. (2016) The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase. Toxicology and Applied Pharmacology 292, pages 94-102.
Crossref
Crossref
Diana G. Wright, Claire Marchal, Kimson Hoang, John A. Ankney, Stephanie T. Nguyen, Amanda W. Rushing, Nicholas Polakowski, Benoit Miotto & Isabelle Lemasson. (2015) Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. Oncotarget 7:2, pages 1687-1706.
Crossref
Crossref
Yue-Li Nan, Yan-Ling Hu, Zhi-Ke Liu, Fang-Fang Duan, Yang Xu, Shu Li, Ting Li, Da-Fang Chen & Xiao-Yun Zeng. (2016) Relationships between cell cycle pathway gene polymorphisms and risk of hepatocellular carcinoma. World Journal of Gastroenterology 22:24, pages 5558.
Crossref
Crossref
X.-J. Yang. 2016. Chromatin Signaling and Diseases. Chromatin Signaling and Diseases
3
23
.
C.L. Brooks. 2016. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology
504
510
.
Nanette H. Bishopric. 2016. Epigenetics in Cardiac Disease. Epigenetics in Cardiac Disease
147
190
.
Martin L. Read, Robert I. Seed, Bhavika Modasia, Perkin P.K. Kwan, Neil Sharma, Vicki E. Smith, Rachel J. Watkins, Sukhchain Bansal, Teresa Gagliano, Anna L. Stratford, Tariq Ismail, Michael J.O. Wakelam, Dae S. Kim, Stephen T. Ward, Kristien Boelaert, Jayne A. Franklyn, Andrew S. Turnell & Christopher J. McCabe. (2016) The proto-oncogene PBF binds p53 and is associated with prognostic features in colorectal cancer. Molecular Carcinogenesis 55:1, pages 15-26.
Crossref
Crossref
Yu-Chin Liu, Pu-Yuan Chang & Chuck C.-K. Chao. (2015) CITED2 silencing sensitizes cancer cells to cisplatin by inhibiting p53 trans-activation and chromatin relaxation on the ERCC1 DNA repair gene. Nucleic Acids Research 43:22, pages 10760-10781.
Crossref
Crossref
Sandrine Caburet, Mikko Anttonen, Anne-Laure Todeschini, Leila Unkila-Kallio, Denis Mestivier, Ralf Butzow & Reiner A Veitia. (2015) Combined comparative genomic hybridization and transcriptomic analyses of ovarian granulosa cell tumors point to novel candidate driver genes. BMC Cancer 15:1.
Crossref
Crossref
France-Hélène Paradis & Barbara F. Hales. (2015) Valproic Acid Induces the Hyperacetylation of P53, Expression of P53 Target Genes, and Markers of the Intrinsic Apoptotic Pathway in Midorganogenesis Murine Limbs. Birth Defects Research Part B: Developmental and Reproductive Toxicology 104:5, pages 177-183.
Crossref
Crossref
A Farria, W Li & S Y R Dent. (2015) KATs in cancer: functions and therapies. Oncogene 34:38, pages 4901-4913.
Crossref
Crossref
Sai-Sai Tang, Bi-Ying Zheng & Xing-Dong Xiong. (2015) LincRNA-p21: Implications in Human Diseases. International Journal of Molecular Sciences 16:8, pages 18732-18740.
Crossref
Crossref
David W. Meek. (2015) Regulation of the p53 response and its relationship to cancer. Biochemical Journal 469:3, pages 325-346.
Crossref
Crossref
Xiao-Jian Sun, Na Man, Yurong Tan, Stephen D. Nimer & Lan Wang. (2015) The Role of Histone Acetyltransferases in Normal and Malignant Hematopoiesis. Frontiers in Oncology 5.
Crossref
Crossref
Yi-Young Choi, Shin Yup Lee, Won Kee Lee, Hyo-Sung Jeon, Eung Bae Lee, Hyun Cheol Lee, Jin Eun Choi, Hyo-Gyoung Kang, Eun Jin Lee, Eun Young Bae, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, In-San Kim, Myung Hoon Lee, Young Tae Kim, Sanghoon Jheon & Jae Yong Park. (2015)
RACK1
is a candidate gene associated with the prognosis of patients with early stage non-small cell lung cancer
. Oncotarget 6:6, pages 4451-4466.
Crossref
Crossref
Morgan A. Sammons, Jiajun Zhu, Adam M. Drake & Shelley L. Berger. (2015) TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity. Genome Research 25:2, pages 179-188.
Crossref
Crossref
Daniel Ansari, Roland Andersson, Monika P. Bauden, Bodil Andersson, Joanne B. Connolly, Charlotte Welinder, Agata Sasor & György Marko-Varga. (2014) Protein deep sequencing applied to biobank samples from patients with pancreatic cancer. Journal of Cancer Research and Clinical Oncology 141:2, pages 369-380.
Crossref
Crossref
Stephanie Kaypee, Somnath Mandal, Snehajyoti Chatterjee & Tapas K. Kundu. 2015. Epigenetic Cancer Therapy. Epigenetic Cancer Therapy
471
494
.
Margherita Ghisi & Ricky W. Johnstone. 2015. Targeted Therapy of Acute Myeloid Leukemia. Targeted Therapy of Acute Myeloid Leukemia
411
439
.
Yingxi Xu, Rong Liao, Na Li, Rong Xiang & Peiqing Sun. (2014) Phosphorylation of Tip60 by p38α regulates p53-mediated PUMA induction and apoptosis in response to DNA damage. Oncotarget 5:24, pages 12555-12572.
Crossref
Crossref
Sara Reed & Dawn Quelle. (2014) p53 Acetylation: Regulation and Consequences. Cancers 7:1, pages 30-69.
Crossref
Crossref
Qian Hao & William Cho. (2014) Battle Against Cancer: An Everlasting Saga of p53. International Journal of Molecular Sciences 15:12, pages 22109-22127.
Crossref
Crossref
Shasha Shi, Juanyu Lin, Yongfei Cai, Jiao Yu, Haiyan Hong, Kunmei Ji, Jennifer S Downey, Xiaodong Lu, Ruichuan Chen, Jiahuai Han & Aidong Han. (2014) Dimeric structure of p300/CBP associated factor. BMC Structural Biology 14:1.
Crossref
Crossref
Gengze WuJin CaiYu HanJinghai ChenZhan-Peng HuangCaiyu ChenYue CaiHefei HuangYujia YangYukai LiuZaicheng XuDuofen HeXiaoqun ZhangXiaoyun HuLuca PinelloDan ZhongFengtian HeGuo-Cheng YuanDa-Zhi WangChunyu Zeng. (2014) LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity. Circulation 130:17, pages 1452-1465.
Crossref
Crossref
Duncan A. HayOleg FedorovSarah MartinDean C. SingletonCynthia TallantChristopher WellsSarah PicaudMartin PhilpottOctovia P. MonteiroCatherine M. RogersStuart J. ConwayTimothy P. C. RooneyAnthony TumberClarence YappPanagis FilippakopoulosMark E. Bunnage, Susanne MüllerStefan KnappChristopher J. SchofieldPaul E. Brennan. (2014) Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains. Journal of the American Chemical Society 136:26, pages 9308-9319.
Crossref
Crossref
Fernanda Wisnieski, Danielle Queiroz Calcagno, Mariana Ferreira Leal, Elizabeth Suchi Chen, Carolina Oliveira Gigek, Leonardo Caires Santos, Thaís Brilhante Pontes, Lucas Trevizani Rasmussen, Spencer Luiz Marques Payão, Paulo Pimentel Assumpção, Laércio Gomes Lourenço, Sâmia Demachki, Ricardo Artigiani, Rommel Rodríguez Burbano & Marília Cardoso Smith. (2014) Differential expression of histone deacetylase and acetyltransferase genes in gastric cancer and their modulation by trichostatin A. Tumor Biology 35:7, pages 6373-6381.
Crossref
Crossref
Nicholas A. Wallace, Kristin Robinson & Denise A. Galloway. (2014) Beta Human Papillomavirus E6 Expression Inhibits Stabilization of p53 and Increases Tolerance of Genomic Instability. Journal of Virology 88:11, pages 6112-6127.
Crossref
Crossref
Nicholas A. Wallace & Denise A. Galloway. (2014) Manipulation of cellular DNA damage repair machinery facilitates propagation of human papillomaviruses. Seminars in Cancer Biology 26, pages 30-42.
Crossref
Crossref
Ling-xia Wang, Jing Wang, Ting-ting Qu, Ye Zhang & Yu-fei Shen. (2014) Reversible acetylation of Lin28 mediated by PCAF and SIRT1. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:6, pages 1188-1195.
Crossref
Crossref
Ariel M. Wilson, Vince A. Chiodo, Sanford L. Boye, Nicholas C. Brecha, William W. Hauswirth & Adriana Di Polo. (2014) Inhibitor of Apoptosis-Stimulating Protein of p53 (iASPP) Is Required for Neuronal Survival after Axonal Injury. PLoS ONE 9:4, pages e94175.
Crossref
Crossref
Martin L. Read, Robert I. Seed, Jim C.W. Fong, Bhavika Modasia, Gavin A. Ryan, Rachel J Watkins, Teresa Gagliano, Vicki E. Smith, Anna L. Stratford, Perkin K Kwan, Neil Sharma, Olivia M. Dixon, John C. Watkinson, Kristien Boelaert, Jayne A. Franklyn, Andrew S. Turnell & Christopher J. McCabe. (2014) The PTTG1-Binding Factor (PBF/PTTG1IP) Regulates p53 Activity in Thyroid Cells. Endocrinology 155:4, pages 1222-1234.
Crossref
Crossref
Wakana Ono, Yuki Hayashi, Wataru Yokoyama, Takao Kuroda, Hiroyuki Kishimoto, Ichiaki Ito, Keiji Kimura, Kensuke Akaogi, Tsuyoshi Waku & Junn Yanagisawa. (2014) The Nucleolar Protein Myb-binding Protein 1A (MYBBP1A) Enhances p53 Tetramerization and Acetylation in Response to Nucleolar Disruption. Journal of Biological Chemistry 289:8, pages 4928-4940.
Crossref
Crossref
Min-Kyoung Kim, Dong Hun Lee, Serah Lee, Eun Ju Kim & Jin Ho Chung. (2014) UV-induced DNA damage and histone modification may involve MMP-1 gene transcription in human skin in vivo. Journal of Dermatological Science 73:2, pages 169-171.
Crossref
Crossref
Caroline J. DeHart, Jasdave S. Chahal, S.J. Flint & David H. Perlman. (2014) Extensive Post-translational Modification of Active and Inactivated Forms of Endogenous p53. Molecular & Cellular Proteomics 13:1, pages 1-17.
Crossref
Crossref
Hwa Hwa Chung, Siu Kwan Sze, Alvin Shun Long Tay & Valerie C.-L. Lin. (2014) Acetylation at Lysine 183 of Progesterone Receptor by p300 Accelerates DNA Binding Kinetics and Transactivation of Direct Target Genes. Journal of Biological Chemistry 289:4, pages 2180-2194.
Crossref
Crossref
Catherine Vaughan, Isabella Pearsall, Andrew Yeudall, Swati Palit Deb & Sumitra Deb. 2014. Mutant p53 and MDM2 in Cancer. Mutant p53 and MDM2 in Cancer
71
90
.
Zhen-Ning Zhang, Sun-Ku Chung, Zheng Xu & Yang Xu. (2014) Oct4 Maintains the Pluripotency of Human Embryonic Stem Cells by Inactivating p53 Through Sirt1-Mediated Deacetylation. Stem Cells 32:1, pages 157-165.
Crossref
Crossref
Diana Marouco, Alexander V. Garabadgiu, Gerry Melino & Nikolai A. Barlev. (2013) Lysine-specific modifications of p53: a matter of life and death?. Oncotarget 4:10, pages 1556-1571.
Crossref
Crossref
Antonio Julià, Eugeni Domènech, Elena Ricart, Raül Tortosa, Valle García-Sánchez, Javier P Gisbert, Pilar Nos Mateu, Ana Gutiérrez, Fernando Gomollón, Juan Luís Mendoza, Esther Garcia-Planella, Manuel Barreiro-de Acosta, Fernando Muñoz, Maribel Vera, Cristina Saro, Maria Esteve, Montserrat Andreu, Arnald Alonso, María López-Lasanta, Laia Codó, Josep Lluís Gelpí, Andres C García-Montero, Jaume Bertranpetit, Devin Absher, Julián Panés & Sara Marsal. (2013)
A genome-wide association study on a southern European population identifies a new Crohn's disease susceptibility locus at
RBX1-EP300
. Gut 62:10, pages 1440-1445.
Crossref
Crossref
Antonius J.N.M. BastiaansenMark M. EwingHetty C. de BoerTineke C. van der Pouw KraanMargreet R. de VriesErna A.B. PetersSabine M.J. WeltenRamon ArensScott M. MooreJames E. FaberJ. Wouter JukemaJaap F. HammingA. Yaël NossentPaul H.A. Quax. (2013) Lysine Acetyltransferase PCAF Is a Key Regulator of Arteriogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology 33:8, pages 1902-1910.
Crossref
Crossref
Nicholas A. Wallace, Stephen L. Gasior, Zachary J. Faber, Heather L. Howie, Prescott L. Deininger & Denise A. Galloway. (2013) HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition. Virology 443:1, pages 69-79.
Crossref
Crossref
Chao-Yang Wang, Shu-Feng Yang, Zhong Wang, Jun-Ming Tan, Shun-Min Xing, De-Chun Chen, Sheng-Ming Xu & Wen Yuan. (2013) PCAF acetylates Runx2 and promotes osteoblast differentiation. Journal of Bone and Mineral Metabolism 31:4, pages 381-389.
Crossref
Crossref
Nansong Liu, Jiadong Wang, Jifeng Wang, Rukai Wang, Zhongle Liu, Yao Yu & Hong Lu. (2013) ING5 Is a Tip60 Cofactor That Acetylates p53 in Response to DNA Damage. Cancer Research 73:12, pages 3749-3760.
Crossref
Crossref
K.-Y. Hsiao & C. A. Mizzen. (2013) Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair. Journal of Molecular Cell Biology 5:3, pages 157-165.
Crossref
Crossref
Meili Shen, Tingting Zhou, Wenbing Xie, Te Ling, Qiaoyun Zhu, Le Zong, Guoliang Lyu, Qianqian Gao, Feixiong Zhang & Wei Tao. (2013) The Chromatin Remodeling Factor CSB Recruits Histone Acetyltransferase PCAF to rRNA Gene Promoters in Active State for Transcription Initiation. PLoS ONE 8:5, pages e62668.
Crossref
Crossref
MARTINE MÜLLER KLOSTER, ELIN HALLAN NADERI, INGVILD HAALAND, BJØRN TORE GJERTSEN, HEIDI KIIL BLOMHOFF & SOHEIL NADERI. (2013) cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases. International Journal of Oncology 42:5, pages 1815-1821.
Crossref
Crossref
Subhalaxmi Nambi, Kallol Gupta, Moitrayee Bhattacharyya, Parvathy Ramakrishnan, Vaishnavi Ravikumar, Nida Siddiqui, Ann Terene Thomas & Sandhya S. Visweswariah. (2013) Cyclic AMP-dependent Protein Lysine Acylation in Mycobacteria Regulates Fatty Acid and Propionate Metabolism. Journal of Biological Chemistry 288:20, pages 14114-14124.
Crossref
Crossref
Luis A Carvajal & James J Manfredi. (2013) Another fork in the road—life or death decisions by the tumour suppressor p53. EMBO reports 14:5, pages 414-421.
Crossref
Crossref
Wakana Ono, Kensuke Akaogi, Tsuyoshi Waku, Takao Kuroda, Wataru Yokoyama, Yuki Hayashi, Keiji Kimura, Hiroyuki Kishimoto & Junn Yanagisawa. (2013) Nucleolar protein, Myb-binding protein 1A, specifically binds to nonacetylated p53 and efficiently promotes transcriptional activation. Biochemical and Biophysical Research Communications 434:3, pages 659-663.
Crossref
Crossref
Risheng XuNilkantha SenBindu D. PaulAdele M. SnowmanFeng RaoM. Scott VandiverJing XuSolomon H. Snyder. (2013) Inositol Polyphosphate Multikinase Is a Coactivator of p53-Mediated Transcription and Cell Death. Science Signaling 6:269.
Crossref
Crossref
Maren Eckey, Florian Kraft, Robert Kob, Niko Escher, Mohammad Asim, Heike Fischer, Marie K. Fritsche, Christian Melle & Aria Baniahmad. (2013) The corepressor activity of Alien is controlled by CREB-binding protein/p300. FEBS Journal 280:8, pages 1861-1868.
Crossref
Crossref
Displaying 200 of 561 citing articles. Use the download link below to view the full list of citing articles.
Download full citations list