15
Views
107
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

Dominant Activity of Activation Function 1 (AF-1) and Differential Stoichiometric Requirements for AF-1 and -2 in the Estrogen Receptor α-β Heterodimeric Complex

, , &
Pages 1919-1927 | Received 16 Oct 1998, Accepted 01 Dec 1998, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Nathalie Picard, Véronique Caron, Stéphanie Bilodeau, Mélanie Sanchez, Xavier Mascle, Muriel Aubry & André Tremblay. (2012) Identification of Estrogen Receptor β as a SUMO-1 Target Reveals a Novel Phosphorylated Sumoylation Motif and Regulation by Glycogen Synthase Kinase 3β. Molecular and Cellular Biology 32:14, pages 2709-2721.
Read now
Xiaodong Li, Jing Huang, Ping Yi, Robert A. Bambara, Russell Hilf & Mesut Muyan. (2004) Single-Chain Estrogen Receptors (ERs) Reveal that the ERα/β Heterodimer Emulates Functions of the ERα Dimer in Genomic Estrogen Signaling Pathways. Molecular and Cellular Biology 24:17, pages 7681-7694.
Read now

Articles from other publishers (105)

Bin Yuan, Long Cheng, Kshama Gupta, Huai-Chin Chiang, Harshita B. Gupta, Gangadhara R. Sareddy, Degeng Wang, Kate Lathrop, Richard Elledge, Pei Wang, Stanton McHardy, Ratna Vadlamudi, Tyler J. Curiel, Yanfen Hu, Qinong Ye & Rong Li. (2016) Tyrosine phosphorylation regulates ERβ ubiquitination, protein turnover, and inhibition of breast cancer. Oncotarget 7:27, pages 42585-42597.
Crossref
Rais A. Ansari, Saleh Alfuraih, Kamran Shekh, Yadollah Omidi, Saleem Javed & Saghir A. Shakil. 2023. Impact of Engineered Nanomaterials in Genomics and Epigenomics. Impact of Engineered Nanomaterials in Genomics and Epigenomics 41 82 .
Amandine Vallet, Mohamed El Ezzy, Marine Diennet, Salwa Haidar, Michel Bouvier & Sylvie Mader. (2023) The AF-2 cofactor binding region is key for the selective SUMOylation of estrogen receptor alpha by antiestrogens. Journal of Biological Chemistry 299:1, pages 102757.
Crossref
Deborah S. Souza, Ana Paola G. Lombardi, Carolina M. Vicente, Thaís Fabiana G. Lucas, Adolfo G. Erustes, Gustavo J.S. Pereira & Catarina S. Porto. (2019) Estrogen receptors localization and signaling pathways in DU-145 human prostate cancer cells. Molecular and Cellular Endocrinology 483, pages 11-23.
Crossref
B. Madhu Krishna, Sanjib Chaudhary, Dipti Ranjan Mishra, Sanoj K. Naik, S. Suklabaidya, A. K. Adhya & Sandip K. Mishra. (2018) Estrogen receptor α dependent regulation of estrogen related receptor β and its role in cell cycle in breast cancer. BMC Cancer 18:1.
Crossref
David Cotnoir-WhiteMohamed El EzzyPierre-Luc BoulayMarieke RozendaalMichel Bouvier, Etienne GagnonSylvie Mader. (2018) Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect. Proceedings of the National Academy of Sciences 115:11.
Crossref
Carlos G. Coriano, Fabao Liu, Chelsie K. Sievers, Muxuan Liang, Yidan Wang, Yoongho Lim, Menggang Yu & Wei Xu. (2018) A Computational-Based Approach to Identify Estrogen Receptor α / β Heterodimer Selective Ligands . Molecular Pharmacology 93:3, pages 197-207.
Crossref
C. K. Kim, A. Torcaso, A. Asimes, W. C. J. Chung & T. R. Pak. (2018) Structural and functional characteristics of oestrogen receptor β splice variants: Implications for the ageing brain. Journal of Neuroendocrinology 30:2, pages e12488.
Crossref
Pelin Yaşar, Gamze Ayaz, Sırma Damla User, Gizem Güpür & Mesut Muyan. (2017) Molecular mechanism of estrogen-estrogen receptor signaling. Reproductive Medicine and Biology 16:1, pages 4-20.
Crossref
Masao Izawa, Fuminori Taniguchi & Tasuku Harada. (2016) Molecular Background of Estrogen Receptor Gene Expression in Endometriotic Cells. Reproductive Sciences 23:7, pages 871-876.
Crossref
I Robertshaw, F Bian & S K Das. (2016) Mechanisms of uterine estrogen signaling during early pregnancy in mice: an update. Journal of Molecular Endocrinology 56:3, pages R127-R138.
Crossref
Susana I. Sá, Bruno M. Fonseca, Natércia Teixeira & M. Dulce Madeira. (2015) Estrogen receptors α and β have different roles in the induction and trafficking of progesterone receptors in hypothalamic ventromedial neurons. The FEBS Journal 282:6, pages 1126-1136.
Crossref
D.K. Hapangama, A.M. Kamal & J.N. Bulmer. (2015) Estrogen receptor β: the guardian of the endometrium. Human Reproduction Update 21:2, pages 174-193.
Crossref
David P. Marciano, Mi Ra Chang, Cesar A. Corzo, Devrishi Goswami, Vinh Q. Lam, Bruce D. Pascal & Patrick R. Griffin. (2014) The Therapeutic Potential of Nuclear Receptor Modulators for Treatment of Metabolic Disorders: PPARγ, RORs, and Rev-erbs. Cell Metabolism 19:2, pages 193-208.
Crossref
Yuki OGO, Shusuke TANIUCHI, Fumiya OJIMA, Sayo HAYASHI, Itsuo MURAKAMI, Yuka SAITO, Sakae TAKEUCHI, Toshiyuki KUDO & Sumio TAKAHASHI. (2014) IGF-1 Gene Expression Is Differentially Regulated by Estrogen Receptors α and β in Mouse Endometrial Stromal Cells and Ovarian Granulosa Cells. Journal of Reproduction and Development 60:3, pages 216-223.
Crossref
Mi Ra Chang, Hugh Rosen & Patrick R. Griffin. 2014. Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases. Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases 171 182 .
Derek A. Schreihofer & Yulin Ma. (2013) Estrogen receptors and ischemic neuroprotection: Who, what, where, and when?. Brain Research 1514, pages 107-122.
Crossref
Shuang Liu, Sang Jun Han & Carolyn L. Smith. (2013) Cooperative Activation of Gene Expression by Agonists and Antagonists Mediated by Estrogen Receptor Heteroligand Dimer Complexes. Molecular Pharmacology 83:5, pages 1066-1077.
Crossref
N. N. Mott & T. R. Pak. (2012) Characterisation of Human Oestrogen Receptor beta (ERβ) Splice Variants in Neuronal Cells. Journal of Neuroendocrinology 24:10, pages 1311-1321.
Crossref
Sandipan Chakraborty, Hadassah Willett & P.K. Biswas. (2012) Insight into estrogen receptor beta–beta and alpha–beta homo- and heterodimerization: A combined molecular dynamics and sequence analysis study. Biophysical Chemistry 170, pages 42-50.
Crossref
Linda S.M. Gulliver & Peter R. Hurst. (2012) Repeat estradiol exposure differentially regulates protein expression patterns for estrogen receptor and E-cadherin in older mouse ovarian surface epithelium: Implications for replacement and adjuvant hormone therapies?. Steroids 77:6, pages 674-685.
Crossref
Emily Powell, Erin Shanle, Ashley Brinkman, Jun Li, Sunduz Keles, Kari B. Wisinski, Wei Huang & Wei Xu. (2012) Identification of Estrogen Receptor Dimer Selective Ligands Reveals Growth-Inhibitory Effects on Cells That Co-Express ERα and ERβ. PLoS ONE 7:2, pages e30993.
Crossref
Tristan M. Nicholson & William A. Ricke. (2011) Androgens and estrogens in benign prostatic hyperplasia: Past, present and future. Differentiation 82:4-5, pages 184-199.
Crossref
Linda S. M. Gulliver & Peter R. Hurst. (2011) Novel Approaches to Quantify Estradiol-Induced Loss of ERβ1 Protein in Older Mouse Ovarian Surface Epithelium: New Tools to Assess the Role of ER Protein Subtypes in Predisposing to Ovarian Epithelial Cancer?. Hormones and Cancer 2:4, pages 204-213.
Crossref
Yukiko Ogino, Shinichi Miyagawa, Hironori Katoh, Gail S. Prins, Taisen Iguchi & Gen Yamada. (2011) Essential functions of androgen signaling emerged through the developmental analysis of vertebrate sex characteristics. Evolution & Development 13:3, pages 315-325.
Crossref
Julien Savatier, Stéphan Jalaguier, Matthew L. Ferguson, Vincent Cavaillès & Catherine A. Royer. (2010) Estrogen Receptor Interactions and Dynamics Monitored in Live Cells by Fluorescence Cross-Correlation Spectroscopy. Biochemistry 49:4, pages 772-781.
Crossref
Tze Howe Charn, Edison Tak-Bun Liu, Edmund C. Chang, Yew Kok Lee, John A. Katzenellenbogen & Benita S. Katzenellenbogen. (2010) Genome-Wide Dynamics of Chromatin Binding of Estrogen Receptors α and β: Mutual Restriction and Competitive Site Selection. Molecular Endocrinology 24:1, pages 47-59.
Crossref
Vincent Giguère. 2010. Handbook of Cell Signaling. Handbook of Cell Signaling 2015 2019 .
Stefan Nilsson & Jan-Åke Gustafsson. 2010. Nuclear Receptors. Nuclear Receptors 91 141 .
Yukiko Ogino, Hironori Katoh, Shigehiro Kuraku & Gen Yamada. (2009) Evolutionary History and Functional Characterization of Androgen Receptor Genes in Jawed Vertebrates. Endocrinology 150:12, pages 5415-5427.
Crossref
David Hyacinthe Aboghe, Mayumi Yoshioka, Daniel Phaneuf & Jonny St-Amand. (2009) Regulation of gene expression by estrogen in mammary gland of wild type and estrogen receptor alpha knockout mice. The Journal of Steroid Biochemistry and Molecular Biology 113:1-2, pages 116-126.
Crossref
Emily Powell & Wei Xu. (2008) Intermolecular interactions identify ligand-selective activity of estrogen receptor α/β dimers. Proceedings of the National Academy of Sciences 105:48, pages 19012-19017.
Crossref
Eric A. Ariazi & V. Craig Jordan. 2008. Nuclear Receptors as Drug Targets. Nuclear Receptors as Drug Targets 127 199 .
Marilyn K. Glassberg, Sharon J. Elliot, Jason Fritz, Paola Catanuto, Mylene Potier, Roger Donahue, William Stetler-Stevenson & Michael Karl. (2008) Activation of the Estrogen Receptor Contributes to the Progression of Pulmonary Lymphangioleiomyomatosis via Matrix Metalloproteinase-Induced Cell Invasiveness. The Journal of Clinical Endocrinology & Metabolism 93:5, pages 1625-1633.
Crossref
Xiaodong Li, Jing Huang, Brian R. Fluharty, Yanfang Huang, Stephanie L. Nott & Mesut Muyan. (2008) What are comparative studies telling us about the mechanism of ERβ action in the ERE-dependent E2 signaling pathway?. The Journal of Steroid Biochemistry and Molecular Biology 109:3-5, pages 266-272.
Crossref
Sylvain Baron, Aurélie Escande, Géraldine Albérola, Kerstin Bystricky, Patrick Balaguer & Hélène Richard-Foy. (2007) Estrogen Receptor α and the Activating Protein-1 Complex Cooperate during Insulin-like Growth Factor-I-induced Transcriptional Activation of the pS2/TFF1 Gene. Journal of Biological Chemistry 282:16, pages 11732-11741.
Crossref
J. D. Blaustein & S. K. Mani. 2007. Handbook of Neurochemistry and Molecular Neurobiology. Handbook of Neurochemistry and Molecular Neurobiology 95 149 .
Ulrich OhnemusMurat UenalanJosé InzunzaJan-Åke GustafssonRalf Paus. (2006) The Hair Follicle as an Estrogen Target and Source. Endocrine Reviews 27:6, pages 677-706.
Crossref
Paola Galluzzo & Maria Marino. (2006) Nutritional flavonoids impact on nuclear and extranuclear estrogen receptor activities. Genes & Nutrition 1:3-4, pages 161-176.
Crossref
Ting Lu, Yamini Achari, Paul Sciore & D.A. Hart. (2006) Estrogen receptor alpha regulates matrix metalloproteinase-13 promoter activity primarily through the AP-1 transcriptional regulatory site. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1762:8, pages 719-731.
Crossref
Toshiharu Iwasaki, Akira Takeshita, Wataru Miyazaki, William W. Chin & Noriyuki Koibuchi. (2006) The Interaction of TRβ1-N Terminus with Steroid Receptor Coactivator-1 (SRC-1) Serves a Full Transcriptional Activation Function of SRC-1. Endocrinology 147:3, pages 1452-1457.
Crossref
Kristen L. Koterba & Brian G. Rowan. (2006) Measuring ligand-dependent and ligand-independent interactions between nuclear receptors and associated proteins using Bioluminescence Resonance Energy Transfer (BRET 2 ) . Nuclear Receptor Signaling 4:1, pages nrs.04021.
Crossref
Cristian Bodo, Andrea E. Kudwa & Emilie F. Rissman. (2006) Both Estrogen Receptor-α and -β Are Required for Sexual Differentiation of the Anteroventral Periventricular Area in Mice. Endocrinology 147:1, pages 415-420.
Crossref
Graziella Penot, Christine Le Péron, Yohann Mérot, Eva Grimaud-Fanouillère, François Ferrière, Noureddine Boujrad, Olivier Kah, Christian Saligaut, Bernadette Ducouret, Raphaël Métivier & Gilles Flouriot. (2005) The Human Estrogen Receptor-α Isoform hERα46 Antagonizes the Proliferative Influence of hERα66 in MCF7 Breast Cancer Cells. Endocrinology 146:12, pages 5474-5484.
Crossref
Jing Huang, Xiaodong Li, Casey A. Maguire, Russell Hilf, Robert A. Bambara & Mesut Muyan. (2005) Binding of Estrogen Receptor β to Estrogen Response Element in Situ Is Independent of Estradiol and Impaired by Its Amino Terminus. Molecular Endocrinology 19:11, pages 2696-2712.
Crossref
Takeshi Kurita, Roanna Medina, Alex B. Schabel, Peter Young, Patricia Gama, Trilok V. Parekh, Joel Brody, Gerald R. Cunha, Kevin G. Osteen, Kaylon L. Bruner-Tran & Leslie I. Gold. (2005) The activation function-1 domain of estrogen receptor α in uterine stromal cells is required for mouse but not human uterine epithelial response to estrogen. Differentiation 73:6, pages 313-322.
Crossref
Véronique St-Laurent, Mélanie Sanchez, Catherine Charbonneau & André Tremblay. (2005) Selective hormone-dependent repression of estrogen receptor beta by a p38-activated ErbB2/ErbB3 pathway. The Journal of Steroid Biochemistry and Molecular Biology 94:1-3, pages 23-37.
Crossref
Stefan Nilsson & Konrad F. Koehler. (2005) Oestrogen Receptors and Selective Oestrogen Receptor Modulators: Molecular and Cellular Pharmacology. Basic <html_ent glyph="@amp;" ascii="&"/> Clinical Pharmacology <html_ent glyph="@amp;" ascii="&"/> Toxicology 96:1, pages 15-25.
Crossref
Carlos Martínez-Campa, Pedro Zuazua, Juana María García-Pedrero, Pedro Casado, Pedro Sánchez Lazo & Sofía Ramos. 2005. Hormonal Carcinogenesis IV. Hormonal Carcinogenesis IV 391 397 .
Bin He, Robert T. GampeJr.Jr., Adam J. Kole, Andrew T. Hnat, Thomas B. Stanley, Gang An, Eugene L. Stewart, Rebecca I. Kalman, John T. Minges & Elizabeth M. Wilson. (2004) Structural Basis for Androgen Receptor Interdomain and Coactivator Interactions Suggests a Transition in Nuclear Receptor Activation Function Dominance. Molecular Cell 16:3, pages 425-438.
Crossref
Hitoshi Kojo, Kaoru Tajima, Masao Fukagawa, Takao Isogai & Shintaro Nishimura. (2004) Molecular cloning and characterization of two novel human RXRα splice variants. The Journal of Steroid Biochemistry and Molecular Biology 92:1-2, pages 19-28.
Crossref
Yohann Mérot, Raphaël Métivier, Graziella Penot, Dominique Manu, Christian Saligaut, Frank Gannon, Farzad Pakdel, Olivier Kah & Gilles Flouriot. (2004) The Relative Contribution Exerted by AF-1 and AF-2 Transactivation Functions in Estrogen Receptor α Transcriptional Activity Depends upon the Differentiation Stage of the Cell. Journal of Biological Chemistry 279:25, pages 26184-26191.
Crossref
Franziska Conrad & Ralf Paus. (2004) Estrogens and the hair follicle. Ostrogene und der Haarfollikel. Journal der Deutschen Dermatologischen Gesellschaft 2:6, pages 412-423.
Crossref
Carlo Palmieri, Eric W.-F. Lam, Janine Mansi, Claire MacDonald, Sami Shousha, Peter Madden, Yoko Omoto, Andrew Sunters, Margaret Warner, Jan-Åke Gustafsson & R. Charles Coombes. (2004) The Expression of ERβcx in Human Breast Cancer and the Relationship to Endocrine Therapy and Survival. Clinical Cancer Research 10:7, pages 2421-2428.
Crossref
Tara Sabo-Attwood, Kevin J Kroll & Nancy D Denslow. (2004) Differential expression of largemouth bass (Micropterus salmoides) estrogen receptor isotypes alpha, beta, and gamma by estradiol. Molecular and Cellular Endocrinology 218:1-2, pages 107-118.
Crossref
Ya-Ping Lu, Mei Zeng, Dick F Swaab, Rivka Ravid & Jiang-Ning Zhou. (2004) Colocalization and alteration of estrogen receptor-α and -β in the hippocampus in Alzheimer’s disease. Human Pathology 35:3, pages 275-280.
Crossref
GARY M. KAMMER. 2004. Principles of Gender-Specific Medicine. Principles of Gender-Specific Medicine 1082 1092 .
Chi Keung Cheng, Billy K. C. Chow & Peter C. K. Leung. (2003) An Activator Protein 1-Like Motif Mediates 17β-Estradiol Repression of Gonadotropin-Releasing Hormone Receptor Promoter via an Estrogen Receptor α-Dependent Mechanism in Ovarian and Breast Cancer Cells. Molecular Endocrinology 17:12, pages 2613-2629.
Crossref
Paul Webb, Cathleen Valentine, Phuong Nguyen, Richard H PriceJrJr, Adhirai Marimuthu, Brian L West, John D Baxter & Peter J Kushner. (2003) ERβ Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus. Nuclear Receptor 1:1.
Crossref
Yayoi IkedaAkiko Nagai, Masa-Aki Ikeda & Shinji Hayashi. (2003) Sexually Dimorphic and Estrogen-Dependent Expression of Estrogen Receptor β in the Ventromedial Hypothalamus during Rat Postnatal Development. Endocrinology 144:11, pages 5098-5104.
Crossref
Oliver Treeck, Angela Weber, Michaela Boester, Simone Porz, Nicola Frey, Klaus Diedrich & Olaf Ortmann. (2003) H-ras Dependent Estrogenic Effects of Epidermal Growth Factor in the Estrogen-Independent Breast Cancer Cell Line MDA-MB-231. Breast Cancer Research and Treatment 80:2, pages 155-162.
Crossref
Yuichiro Tanaka, Masahiro Sasaki, Masanori Kaneuchi, Seiichiro Fujimoto & Rajvir Dahiya. (2003) Estrogen receptor alpha polymorphisms and renal cell carcinoma—a possible risk. Molecular and Cellular Endocrinology 202:1-2, pages 109-116.
Crossref
Béatrice Gréco, Meg E Blasberg, Eric C Kosinski & Jeffrey D Blaustein. (2003) Response of ERα-IR and ERβ-IR cells in the forebrain of female rats to mating stimuli. Hormones and Behavior 43:4, pages 444-453.
Crossref
Terri L. Gaskell, Lynne L. L. Robinson, Nigel P. Groome, Richard A. Anderson & Philippa T. K. Saunders. (2003) Differential Expression of Two Estrogen Receptor β Isoforms in the Human Fetal Testis during the Second Trimester of Pregnancy. The Journal of Clinical Endocrinology & Metabolism 88:1, pages 424-432.
Crossref
Vincent Giguère. 2003. Handbook of Cell Signaling. Handbook of Cell Signaling 35 38 .
J Gobinet, N Poujol & Ch Sultan. (2002) Molecular action of androgens. Molecular and Cellular Endocrinology 198:1-2, pages 15-24.
Crossref
Maria Elena Torres-Padilla, Frances M. Sladek & Mary C. Weiss. (2002) Developmentally Regulated N-terminal Variants of the Nuclear Receptor Hepatocyte Nuclear Factor 4α Mediate Multiple Interactions through Coactivator and Corepressor-Histone Deacetylase Complexes. Journal of Biological Chemistry 277:47, pages 44677-44687.
Crossref
Ken-ichi Matsuda, Ikuo Ochiai, Mayumi Nishi & Mitsuhiro Kawata. (2002) Colocalization and Ligand-Dependent Discrete Distribution of the Estrogen Receptor (ER)α and ERβ. Molecular Endocrinology 16:10, pages 2215-2230.
Crossref
Sten Z. Cekan. (2002) Genes and transcription factors, including nuclear receptors: Methods of studying their interactions. Journal of Laboratory and Clinical Medicine 140:4, pages 215-227.
Crossref
Ceylan Isgor, Grace C Huang, Huda Akil & Stanley J Watson. (2002) Correlation of estrogen β-receptor messenger RNA with endogenous levels of plasma estradiol and progesterone in the female rat hypothalamus, the bed nucleus of stria terminalis and the medial amygdala. Molecular Brain Research 106:1-2, pages 30-41.
Crossref
Meng-Min Liu, Chris Albanese, Carol M. Anderson, Kristin Hilty, Paul Webb, Rosalie M. Uht, Richard H. PriceJr.Jr., Richard G. Pestell & Peter J. Kushner. (2002) Opposing Action of Estrogen Receptors α and β on Cyclin D1 Gene Expression. Journal of Biological Chemistry 277:27, pages 24353-24360.
Crossref
Dayami Lopez, Mark D. Sanchez, Wendy Shea-Eaton & Mark P. McLean. (2002) Estrogen Activates the High-Density Lipoprotein Receptor Gene via Binding to Estrogen Response Elements and Interaction with Sterol Regulatory Element Binding Protein-1A. Endocrinology 143:6, pages 2155-2168.
Crossref
Arnaud Menuet, Elisabeth Pellegrini, Isabelle Anglade, Odile Blaise, Vincent Laudet, Olivier Kah & Farzad Pakdel. (2002) Molecular Characterization of Three Estrogen Receptor Forms in Zebrafish: Binding Characteristics, Transactivation Properties, and Tissue Distributions1. Biology of Reproduction 66:6, pages 1881-1892.
Crossref
Patrick Diel. (2002) Tissue-specific estrogenic response and molecular mechanisms. Toxicology Letters 127:1-3, pages 217-224.
Crossref
Neal G. Simon. 2002. Hormones, Brain and Behavior. Hormones, Brain and Behavior 339 I .
Jeffrey D. Blaustein & Mary S. Erskine. 2002. Hormones, Brain and Behavior. Hormones, Brain and Behavior 139 214 .
Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 308 335 .
Paul Webb. 2002. Selective Estrogen Receptor Modulators. Selective Estrogen Receptor Modulators 57 76 .
Stefan Nilsson & Jan-Åke Gustafsson. 2002. Selective Estrogen Receptor Modulators. Selective Estrogen Receptor Modulators 3 18 .
Stefanie DengerGeorge ReidMartin KošGilles FlouriotDominik ParschHeike BrandKenneth S. Korach, Vera Sonntag-BuckFrank Gannon. (2001) ERα Gene Expression in Human Primary Osteoblasts: Evidence for the Expression of Two Receptor Proteins. Molecular Endocrinology 15:12, pages 2064-2077.
Crossref
Béatrice Gréco, E. A. Allegretto, M. J. Tetel & J. D. Blaustein. (2001) Coexpression of ERβ with ERα and Progestin Receptor Proteins in the Female Rat Forebrain: Effects of Estradiol Treatment. Endocrinology 142:12, pages 5172-5181.
Crossref
Elisabeth Jisa, Eva Dornstauder, Sumito Ogawa, Sathoshi Inoue, Masami Muramatsu & Alois Jungbauer. (2001) Transcriptional activities of estrogen receptor alpha and beta in yeast properties of raloxifene 1 1Abbreviations: ERE, estrogen response element; E2, 17β-estradiol; RAL, raloxifene; ERα, estrogen receptor α; ERβ, estrogen receptor β; and SERM, selective estrogen receptor modulator.. Biochemical Pharmacology 62:7, pages 953-961.
Crossref
Mesut Muyan, Ping Yi, Ganesan Sathya, Leslie J. Willmert, Mark D. Driscoll, Russell Hilf & Robert A. Bambara. (2001) Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists. Molecular and Cellular Endocrinology 182:2, pages 249-263.
Crossref
Simone Nuedling, Richard H. Karas, Michael E. Mendelsohn, John A. Katzenellenbogen, Benita S. Katzenellenbogen, Rainer Meyer, Hans Vetter & Christian Grohé. (2001) Activation of estrogen receptor β is a prerequisite for estrogen-dependent upregulation of nitric oxide synthases in neonatal rat cardiac myocytes. FEBS Letters 502:3, pages 103-108.
Crossref
Nancy D. Denslow, H.Stephen Lee, Christopher J. Bowman, Michael J. Hemmer & Leroy C. Folmar. (2001) Multiple responses in gene expression in fish treated with estrogen. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 129:2-3, pages 277-282.
Crossref
Monika Jakacka, Masafumi Ito, Jeffrey Weiss, Pei-Yu Chien, Barry D. Gehm & J. Larry Jameson. (2001) Estrogen Receptor Binding to DNA Is Not Required for Its Activity through the Nonclassical AP1 Pathway. Journal of Biological Chemistry 276:17, pages 13615-13621.
Crossref
Katarina PetterssonJan-Åke Gustafsson. (2001) Role of Estrogen Receptor Beta in Estrogen Action. Annual Review of Physiology 63:1, pages 165-192.
Crossref
Emmanuel Margeat, Nicolas Poujol, Abdelhay Boulahtouf, Yan Chen, Joachim D Müller, Enrico Gratton, Vincent Cavailles & Catherine A Royer. (2001) The human estrogen receptor α dimer binds a single SRC-1 coactivator molecule with an affinity dictated by agonist structure11Edited by K. Yamamoto. Journal of Molecular Biology 306:3, pages 433-442.
Crossref
Fernand Labrie, Claude Labrie, Alain Bélanger, Vincent Giguere, Jacques Simard, Yves Mérand, Sylvain Gauthier, Van Luu-The, Bernard Candas, Céline Martel & Shouqi Luo. 2001. Drug Discovery and Design. Drug Discovery and Design 293 368 .
Sophia E. Prinsloo & Casper H. Van Aswegen. 2001. Advances in Clinical Chemistry Volume 35. Advances in Clinical Chemistry Volume 35 101 160 .
Matthew Pavao & Abdulmaged M Traish. (2001) Estrogen receptor antibodies: specificity and utility in detection, localization and analyses of estrogen receptor α and β. Steroids 66:1, pages 1-16.
Crossref
Christian BehlChristian Behl. 2001. Estrogen — Mystery Drug for the Brain?. Estrogen — Mystery Drug for the Brain? 192 224 .
Katarina Pettersson, Franck Delaunay & Jan-Åke Gustafsson. (2000) Estrogen receptor β acts as a dominant regulator of estrogen signaling. Oncogene 19:43, pages 4970-4978.
Crossref
Carolyn M Klinge. (2000) Estrogen receptor interaction with co-activators and co-repressors☆. Steroids 65:5, pages 227-251.
Crossref
Raphaël Métivier, Yves Le Dréan, Gilles Salbert & Farzad Pakdel. (2000) Interplay between liganded and orphan nuclear receptors controls reproductive pathways. Biochemistry and Cell Biology 78:3, pages 345-358.
Crossref
Valerie Speirs, Ian P. Adams, David S. Walton & Stephen L. Atkin. (2000) Identification of Wild-Type and Exon 5 Deletion Variants of Estrogen Receptor β in Normal Human Mammary Gland1. The Journal of Clinical Endocrinology & Metabolism 85:4, pages 1601-1605.
Crossref
Corinna Oberste-Berghaus, Kerstin Zanger, Koshi Hashimoto, Ronald N. Cohen, Anthony N. Hollenberg & Fredric E. Wondisford. (2000) Thyroid Hormone-independent Interaction between the Thyroid Hormone Receptor β2 Amino Terminus and Coactivators. Journal of Biological Chemistry 275:3, pages 1787-1792.
Crossref
Venkatesh Krishnan, Hunter Heath & Henry U. Bryant. 2000. 123 147 .
Derek A. Schreihofer, Eileen M. Resnick & Margaret A. Shupnik. 2000. Gene Engineering in Endocrinology. Gene Engineering in Endocrinology 407 426 .
Diogo S. Castro, Mariette Arvidsson, Maria Bondesson Bolin & Thomas Perlmann. (1999) Activity of the Nurr1 Carboxyl-terminal Domain Depends on Cell Type and Integrity of the Activation Function 2. Journal of Biological Chemistry 274:52, pages 37483-37490.
Crossref
A.S. Levenson & V.C. Jordan. (1999) Selective oestrogen receptor modulation. European Journal of Cancer 35:14, pages 1974-1985.
Crossref
Anke Mueller-Fahrnow & Ursula Egner. (1999) Ligand-binding domain of estrogen receptors. Current Opinion in Biotechnology 10:6, pages 550-556.
Crossref
A.S. Levenson & V.C. Jordan. (1999) Selective oestrogen receptor modulation. European Journal of Cancer 35:12, pages 1628-1639.
Crossref
Paul Webb, Phuong Nguyen, Cathleen Valentine, Gabriela N. Lopez, Grace R. Kwok, Eileen McInerney, Benita S. Katzenellenbogen, Eva Enmark, Jan-Åke Gustafsson, Stefan Nilsson & Peter J. Kushner. (1999) The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions. Molecular Endocrinology 13:10, pages 1672-1685.
Crossref
Fernand Labrie, Claude Labrie, Alain Bélanger, Jacques Simard, Sylvain Gauthier, Van Luu-The, Yves Mérand, Vincent Giguere, Bernard Candas, Shouqi Luo, Céline Martel, Shankar Mohan Singh, Marc Fournier, Agnès Coquet, Virgile Richard, Ronald Charbonneau, Gilles Charpenet, André Tremblay, Gilles Tremblay, Lionel Cusan & Raymonde Veilleux. (1999) EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium. The Journal of Steroid Biochemistry and Molecular Biology 69:1-6, pages 51-84.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.