Molecular and Cellular Biology, Volume 19, Issue 3 (1999)

Browse this journal
Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days

Molecular and Cellular Biology, Volume 19, Issue 3 (1999)

See all volumes and issues
Vol 44, 2024 Vol 43, 2023 Vol 42, 2022 Vol 41, 2021 Vol 40, 2020 Vol 39, 2019 Vol 38, 2018 Vol 37, 2017 Vol 36, 2016 Vol 35, 2015 Vol 34, 2014 Vol 33, 2013 Vol 32, 2012 Vol 31, 2011 Vol 30, 2010 Vol 29, 2009 Vol 28, 2008 Vol 27, 2007 Vol 26, 2006 Vol 25, 2005 Vol 24, 2004 Vol 23, 2003 Vol 22, 2002 Vol 21, 2001 Vol 20, 2000 Volume 19, 1999 Vol 18, 1998 Vol 17, 1997 Vol 16, 1996 Vol 15, 1995 Vol 14, 1994 Vol 13, 1993 Vol 12, 1992 Vol 11, 1991 Vol 10, 1990 Vol 9, 1989 Vol 8, 1988 Vol 7, 1987 Vol 6, 1986 Vol 5, 1985 Vol 4, 1984 Vol 3, 1983 Vol 2, 1982 Vol 1, 1981
Download citations Download PDFs

Transcriptional Regulation

Article
The Amino-Terminal C/H1 Domain of CREB Binding Protein Mediates Zta Transcriptional Activation of Latent Epstein-Barr Virus
Dennis Zerby, Chi-Ju Chen, Ernest Poon, Dan Lee, Ramin Shiekhattar & Paul M. Lieberman
Pages: 1617-1626
Published online: 27 Mar 2023
AbstractforThe Amino-Terminal C/H1 Domain of CREB Binding Protein Mediates Zta Transcriptional Activation of Latent Epstein-Barr Virus | Full Text | References | PDF (1.8 MB)
  • 17 Views
  • 58 CrossRef citations
  • 0Altmetric
Article
Cooperative Binding of Heat Shock Factor to the Yeast HSP82 Promoter In Vivo and In Vitro
Alexander M. Erkine, Serena F. Magrogan, Edward A. Sekinger & David S. Gross
Pages: 1627-1639
Published online: 27 Mar 2023
AbstractforCooperative Binding of Heat Shock Factor to the Yeast HSP82 Promoter In Vivo and In Vitro | Full Text | References | PDF (1.8 MB)
  • 21 Views
  • 68 CrossRef citations
  • 0Altmetric
Article
The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness
Atsuko Masumi, I-Ming Wang, Bruno Lefebvre, Xing-Jiao Yang, Yoshihiro Nakatani & Keiko Ozato
Pages: 1810-1820
Published online: 27 Mar 2023
AbstractforThe Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness | Full Text | References | PDF (1.1 MB)
  • 14 Views
  • 93 CrossRef citations
  • 0Altmetric
Article
Smad3-Smad4 and AP-1 Complexes Synergize in Transcriptional Activation of the c-Jun Promoter by Transforming Growth Factor β
Carolyn Wong, Elissa M. Rougier-Chapman, Joshua P. Frederick, Michael B. Datto, Nicole T. Liberati, Jian-Ming Li & Xiao-Fan Wang
Pages: 1821-1830
Published online: 27 Mar 2023
AbstractforSmad3-Smad4 and AP-1 Complexes Synergize in Transcriptional Activation of the c-Jun Promoter by Transforming Growth Factor β | Full Text | References | PDF (876.5 KB)
  • 55 Views
  • 206 CrossRef citations
  • 0Altmetric
Article
A New Element within the T-Cell Receptor α Locus Required for Tissue-Specific Locus Control Region Activity
Benjamin D. Ortiz, Dragana Cado & Astar Winoto
Pages: 1901-1909
Published online: 27 Mar 2023
AbstractforA New Element within the T-Cell Receptor α Locus Required for Tissue-Specific Locus Control Region Activity | Full Text | References | PDF (2.1 MB)
  • 8 Views
  • 26 CrossRef citations
  • 0Altmetric
Article
The Significance of Tetramerization in Promoter Recruitment by Stat5
Susan John, Uwe Vinkemeier, Elisabetta Soldaini, James E. Darnell Jr. & Warren J. Leonard
Pages: 1910-1918
Published online: 27 Mar 2023
AbstractforThe Significance of Tetramerization in Promoter Recruitment by Stat5 | Full Text | References | PDF (957.7 KB)
  • 41 Views
  • 150 CrossRef citations
  • 0Altmetric
Article
Dominant Activity of Activation Function 1 (AF-1) and Differential Stoichiometric Requirements for AF-1 and -2 in the Estrogen Receptor α-β Heterodimeric Complex
Gilles B. Tremblay, André Tremblay, Fernand Labrie & Vincent Giguère
Pages: 1919-1927
Published online: 27 Mar 2023
AbstractforDominant Activity of Activation Function 1 (AF-1) and Differential Stoichiometric Requirements for AF-1 and -2 in the Estrogen Receptor α-β Heterodimeric Complex | Full Text | References | PDF (470.9 KB)
  • 15 Views
  • 107 CrossRef citations
  • 0Altmetric
Article
Jun Kinase Phosphorylates and Regulates the DNA Binding Activity of an Octamer Binding Protein, T-Cell Factor β1
Shailaja Kasibhatla, Pankaj Tailor, Nathalie Bonefoy-Berard, Tomas Mustelin, Amnon Altman & Arun Fotedar
Pages: 2021-2031
Published online: 27 Mar 2023
AbstractforJun Kinase Phosphorylates and Regulates the DNA Binding Activity of an Octamer Binding Protein, T-Cell Factor β1 | Full Text | References | PDF (2 MB)
  • 19 Views
  • 16 CrossRef citations
  • 0Altmetric
Article
Vascular Endothelial Growth Factor Activates Nuclear Factor of Activated T Cells in Human Endothelial Cells: a Role for Tissue Factor Gene Expression
Angel Luis Armesilla, Elisa Lorenzo, Pablo Gómez del Arco, Sara Martínez-Martínez, Arantzazu Alfranca & Juan Miguel Redondo
Pages: 2032-2043
Published online: 27 Mar 2023
AbstractforVascular Endothelial Growth Factor Activates Nuclear Factor of Activated T Cells in Human Endothelial Cells: a Role for Tissue Factor Gene Expression | Full Text | References | PDF (2.7 MB)
  • 19 Views
  • 151 CrossRef citations
  • 0Altmetric
Article
Nrg1 Is a Transcriptional Repressor for Glucose Repression of STA1 Gene Expression in Saccharomyces cerevisiae
Seok Hee Park, Sang Seok Koh, Jae Hwan Chun, Hye Jin Hwang & Hyen Sam Kang
Pages: 2044-2050
Published online: 27 Mar 2023
AbstractforNrg1 Is a Transcriptional Repressor for Glucose Repression of STA1 Gene Expression in Saccharomyces cerevisiae | Full Text | References | PDF (957.8 KB)
  • 27 Views
  • 82 CrossRef citations
  • 0Altmetric
Article
The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription
Makoto Ohno, Mariastella Zannini, Orlie Levy, Nancy Carrasco & Roberto di Lauro
Pages: 2051-2060
Published online: 27 Mar 2023
AbstractforThe Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription | Full Text | References | PDF (455.5 KB)
  • 27 Views
  • 180 CrossRef citations
  • 0Altmetric
Article
A Novel H2A/H4 Nucleosomal Histone Acetyltransferase in Tetrahymena thermophila
Reiko Ohba, David J. Steger, James E. Brownell, Craig A. Mizzen, Richard G. Cook, Jacques Côté, Jerry L. Workman & C. David Allis
Pages: 2061-2068
Published online: 27 Mar 2023
AbstractforA Novel H2A/H4 Nucleosomal Histone Acetyltransferase in Tetrahymena thermophila | Full Text | References | PDF (566.8 KB)
  • 8 Views
  • 36 CrossRef citations
  • 0Altmetric
Article
A Conserved Motif in Goosecoid Mediates Groucho-Dependent Repression in Drosophila Embryos
Gerardo Jiménez, C. Peter Verrijzer & David Ish-Horowicz
Pages: 2080-2087
Published online: 27 Mar 2023
AbstractforA Conserved Motif in Goosecoid Mediates Groucho-Dependent Repression in Drosophila Embryos | Full Text | References | PDF (869.1 KB)
  • 7 Views
  • 49 CrossRef citations
  • 0Altmetric
Article
Stable Remodeling of Tailless Nucleosomes by the Human SWI-SNF Complex
Jeffrey R. Guyon, Geeta J. Narlikar, Saïd Sif & Robert E. Kingston
Pages: 2088-2097
Published online: 27 Mar 2023
AbstractforStable Remodeling of Tailless Nucleosomes by the Human SWI-SNF Complex | Full Text | References | PDF (1.8 MB)
  • 23 Views
  • 53 CrossRef citations
  • 0Altmetric
Article
The General Transcription Factors IIA, IIB, IIF, and IIE Are Required for RNA Polymerase II Transcription from the Human U1 Small Nuclear RNA Promoter
T. C. Kuhlman, H. Cho, D. Reinberg & N. Hernandez
Pages: 2130-2141
Published online: 27 Mar 2023
AbstractforThe General Transcription Factors IIA, IIB, IIF, and IIE Are Required for RNA Polymerase II Transcription from the Human U1 Small Nuclear RNA Promoter | Full Text | References | PDF (4.4 MB)
  • 59 Views
  • 49 CrossRef citations
  • 0Altmetric
Article
The Highly Conserved β-Hairpin of the Paired DNA-Binding Domain Is Required for Assembly of Pax-Ets Ternary Complexes
William Wheat, Daniel Fitzsimmons, Heidi Lennox, Susan R. Krautkramer, Lisa N. Gentile, Lawrence P. McIntosh & James Hagman
Pages: 2231-2241
Published online: 27 Mar 2023
AbstractforThe Highly Conserved β-Hairpin of the Paired DNA-Binding Domain Is Required for Assembly of Pax-Ets Ternary Complexes | Full Text | References | PDF (2 MB)
  • 9 Views
  • 45 CrossRef citations
  • 0Altmetric

Gene Expression

Article
A Premature Termination Codon Interferes with the Nuclear Function of an Exon Splicing Enhancer in an Open Reading Frame-Dependent Manner
Anand Gersappe & David J. Pintel
Pages: 1640-1650
Published online: 27 Mar 2023
AbstractforA Premature Termination Codon Interferes with the Nuclear Function of an Exon Splicing Enhancer in an Open Reading Frame-Dependent Manner | Full Text | References | PDF (1.1 MB)
  • 11 Views
  • 27 CrossRef citations
  • 0Altmetric
Article
C/EBPα Regulates Generation of C/EBPβ Isoforms through Activation of Specific Proteolytic Cleavage
Alana L. Welm, Nikolai A. Timchenko & Gretchen J. Darlington
Pages: 1695-1704
Published online: 27 Mar 2023
AbstractforC/EBPα Regulates Generation of C/EBPβ Isoforms through Activation of Specific Proteolytic Cleavage | Full Text | References | PDF (1.3 MB)
  • 14 Views
  • 83 CrossRef citations
  • 0Altmetric
Article
Selection and Characterization of Pre-mRNA Splicing Enhancers: Identification of Novel SR Protein-Specific Enhancer Sequences
Thomas D. Schaal & Tom Maniatis
Pages: 1705-1719
Published online: 27 Mar 2023
AbstractforSelection and Characterization of Pre-mRNA Splicing Enhancers: Identification of Novel SR Protein-Specific Enhancer Sequences | Full Text | References | PDF (1.3 MB)
  • 28 Views
  • 163 CrossRef citations
  • 0Altmetric
Article
Correlation between Protein and mRNA Abundance in Yeast
Steven P. Gygi, Yvan Rochon, B. Robert Franza & Ruedi Aebersold
Pages: 1720-1730
Published online: 27 Mar 2023
AbstractforCorrelation between Protein and mRNA Abundance in Yeast | Full Text | References | PDF (6.9 MB)
  • 505 Views
  • 2811 CrossRef citations
  • 0Altmetric
Article
Substrate Specificities of SR Proteins in Constitutive Splicing Are Determined by Their RNA Recognition Motifs and Composite Pre-mRNA Exonic Elements
Akila Mayeda, Gavin R. Screaton, Sharon D. Chandler, Xiang-Dong Fu & Adrian R. Krainer
Pages: 1853-1863
Published online: 27 Mar 2023
AbstractforSubstrate Specificities of SR Proteins in Constitutive Splicing Are Determined by Their RNA Recognition Motifs and Composite Pre-mRNA Exonic Elements | Full Text | References | PDF (2.8 MB)
  • 16 Views
  • 100 CrossRef citations
  • 0Altmetric
Article
Alterations in the Conserved SL1trans-Spliced Leader of Caenorhabditis elegans Demonstrate Flexibility in Length and Sequence Requirements In Vivo
Kimberly C. Ferguson & Joel H. Rothman
Pages: 1892-1900
Published online: 27 Mar 2023
AbstractforAlterations in the Conserved SL1trans-Spliced Leader of Caenorhabditis elegans Demonstrate Flexibility in Length and Sequence Requirements In Vivo | Full Text | References | PDF (2 MB)
  • 61 Views
  • 15 CrossRef citations
  • 0Altmetric
Article
A Novel Genetic Screen for snRNP Assembly Factors in Yeast Identifies a Conserved Protein, Sad1p, Also Required for Pre-mRNA Splicing
Zoi Lygerou, George Christophides & Bertrand Séraphin
Pages: 2008-2020
Published online: 27 Mar 2023
AbstractforA Novel Genetic Screen for snRNP Assembly Factors in Yeast Identifies a Conserved Protein, Sad1p, Also Required for Pre-mRNA Splicing | Full Text | References | PDF (2.4 MB)
  • 33 Views
  • 45 CrossRef citations
  • 0Altmetric
Article
Pseudouridine Mapping in the Saccharomyces cerevisiae Spliceosomal U Small Nuclear RNAs (snRNAs) Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA
Séverine Massenet, Yuri Motorin, Denis L. J. Lafontaine, Eduard C. Hurt, Henri Grosjean & Christiane Branlant
Pages: 2142-2154
Published online: 27 Mar 2023
AbstractforPseudouridine Mapping in the Saccharomyces cerevisiae Spliceosomal U Small Nuclear RNAs (snRNAs) Reveals that Pseudouridine Synthase Pus1p Exhibits a Dual Substrate Specificity for U2 snRNA and tRNA | Full Text | References | PDF (2.6 MB)
  • 57 Views
  • 107 CrossRef citations
  • 0Altmetric
Article
A Human Sequence Homologue of Staufen Is an RNA-Binding Protein That Is Associated with Polysomes and Localizes to the Rough Endoplasmic Reticulum
Rosa María Marión, Puri Fortes, Ana Beloso, Carlos Dotti & Juan Ortín
Pages: 2212-2219
Published online: 27 Mar 2023
AbstractforA Human Sequence Homologue of Staufen Is an RNA-Binding Protein That Is Associated with Polysomes and Localizes to the Rough Endoplasmic Reticulum | Full Text | References | PDF (957.9 KB)
  • 48 Views
  • 139 CrossRef citations
  • 0Altmetric
Article
Mammalian Staufen Is a Double-Stranded-RNA- and Tubulin-Binding Protein Which Localizes to the Rough Endoplasmic Reticulum
Louise Wickham, Thomas Duchaîne, Ming Luo, Ivan R. Nabi & Luc DesGroseillers
Pages: 2220-2230
Published online: 27 Mar 2023
AbstractforMammalian Staufen Is a Double-Stranded-RNA- and Tubulin-Binding Protein Which Localizes to the Rough Endoplasmic Reticulum | Full Text | References | PDF (1.5 MB)
  • 84 Views
  • 193 CrossRef citations
  • 0Altmetric
Article
Analysis of a Ubiquitous Promoter Element in a Primitive Eukaryote: Early Evolution of the Initiator Element
David R. Liston & Patricia J. Johnson
Pages: 2380-2388
Published online: 27 Mar 2023
AbstractforAnalysis of a Ubiquitous Promoter Element in a Primitive Eukaryote: Early Evolution of the Initiator Element | Full Text | References | PDF (1,010.9 KB)
  • 11 Views
  • 73 CrossRef citations
  • 0Altmetric
Article
NMD3 Encodes an Essential Cytoplasmic Protein Required for Stable 60S Ribosomal Subunits in Saccharomyces cerevisiae
Jennifer Hei-Ngam Ho & Arlen W. Johnson
Pages: 2389-2399
Published online: 27 Mar 2023
AbstractforNMD3 Encodes an Essential Cytoplasmic Protein Required for Stable 60S Ribosomal Subunits in Saccharomyces cerevisiae | Full Text | References | PDF (1.4 MB)
  • 23 Views
  • 75 CrossRef citations
  • 0Altmetric

Cell Growth and Development

Article
Epstein-Barr Virus Regulates c-MYC, Apoptosis, and Tumorigenicity in Burkitt Lymphoma
Ingrid K. Ruf, Paul W. Rhyne, Hui Yang, Corina M. Borza, Lindsey M. Hutt-Fletcher, John L. Cleveland & Jeffery T. Sample
Pages: 1651-1660
Published online: 27 Mar 2023
AbstractforEpstein-Barr Virus Regulates c-MYC, Apoptosis, and Tumorigenicity in Burkitt Lymphoma | Full Text | References | PDF (2.4 MB)
  • 31 Views
  • 106 CrossRef citations
  • 0Altmetric
Article
p50cdc37 Acting in Concert with Hsp90 Is Required for Raf-1 Function
Nicholas Grammatikakis, Jun-Hsiang Lin, Aliki Grammatikakis, Philip N. Tsichlis & Brent H. Cochran
Pages: 1661-1672
Published online: 27 Mar 2023
Abstractforp50cdc37 Acting in Concert with Hsp90 Is Required for Raf-1 Function | Full Text | References | PDF (1.6 MB)
  • 52 Views
  • 203 CrossRef citations
  • 0Altmetric
Article
Ral-Specific Guanine Nucleotide Exchange Factor Activity Opposes Other Ras Effectors in PC12 Cells by Inhibiting Neurite Outgrowth
Takanori Goi, Gabriel Rusanescu, Takeshi Urano & Larry A. Feig
Pages: 1731-1741
Published online: 27 Mar 2023
AbstractforRal-Specific Guanine Nucleotide Exchange Factor Activity Opposes Other Ras Effectors in PC12 Cells by Inhibiting Neurite Outgrowth | Full Text | References | PDF (2.4 MB)
  • 7 Views
  • 76 CrossRef citations
  • 0Altmetric
Article
The Cytoskeletal Network Controls c-Jun Expression and Glucocorticoid Receptor Transcriptional Activity in an Antagonistic and Cell-Type-Specific Manner
Anat Oren, Avia Herschkovitz, Iris Ben-Dror, Vered Holdengreber, Yehuda Ben-Shaul, Rony Seger & Lily Vardimon
Pages: 1742-1750
Published online: 27 Mar 2023
AbstractforThe Cytoskeletal Network Controls c-Jun Expression and Glucocorticoid Receptor Transcriptional Activity in an Antagonistic and Cell-Type-Specific Manner | Full Text | References | PDF (3 MB)
  • 13 Views
  • 34 CrossRef citations
  • 0Altmetric
Article
Regulation of p53 Function and Stability by Phosphorylation
Margaret Ashcroft, Michael H. G. Kubbutat & Karen H. Vousden
Pages: 1751-1758
Published online: 27 Mar 2023
AbstractforRegulation of p53 Function and Stability by Phosphorylation | Full Text | References | PDF (2.1 MB)
  • 102 Views
  • 335 CrossRef citations
  • 0Altmetric
Article
The Abundance of Cell Cycle Regulatory Protein Cdc4p Is Controlled by Interactions between Its F Box and Skp1p
Neal Mathias, Steve Johnson, Breck Byers & Mark Goebl
Pages: 1759-1767
Published online: 27 Mar 2023
AbstractforThe Abundance of Cell Cycle Regulatory Protein Cdc4p Is Controlled by Interactions between Its F Box and Skp1p | Full Text | References | PDF (1.9 MB)
  • 2 Views
  • 38 CrossRef citations
  • 0Altmetric
Article
Activation of c-Jun N-Terminal Kinase 1 by UV Irradiation Is Inhibited by Wortmannin without Affecting c-jun Expression
G. Fritz & B. Kaina
Pages: 1768-1774
Published online: 27 Mar 2023
AbstractforActivation of c-Jun N-Terminal Kinase 1 by UV Irradiation Is Inhibited by Wortmannin without Affecting c-jun Expression | Full Text | References | PDF (1.6 MB)
  • 8 Views
  • 51 CrossRef citations
  • 0Altmetric
Article
Cyclin D-CDK Subunit Arrangement Is Dependent on the Availability of Competing INK4 and p21 Class Inhibitors
David Parry, Daniel Mahony, Ken Wills & Emma Lees
Pages: 1775-1783
Published online: 27 Mar 2023
AbstractforCyclin D-CDK Subunit Arrangement Is Dependent on the Availability of Competing INK4 and p21 Class Inhibitors | Full Text | References | PDF (1.5 MB)
  • 23 Views
  • 125 CrossRef citations
  • 0Altmetric
Article
The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase
Christiane R. Maroun, Marina Holgado-Madruga, Isabelle Royal, Monica A. Naujokas, Tanya M. Fournier, Albert J. Wong & Morag Park
Pages: 1784-1799
Published online: 27 Mar 2023
AbstractforThe Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase | Full Text | References | PDF (10.2 MB)
  • 26 Views
  • 158 CrossRef citations
  • 0Altmetric
Article
Cell Growth Inhibition by Farnesyltransferase Inhibitors Is Mediated by Gain of Geranylgeranylated RhoB
Wei Du, Peter F. Lebowitz & George C. Prendergast
Pages: 1831-1840
Published online: 27 Mar 2023
AbstractforCell Growth Inhibition by Farnesyltransferase Inhibitors Is Mediated by Gain of Geranylgeranylated RhoB | Full Text | References | PDF (3.4 MB)
  • 20 Views
  • 196 CrossRef citations
  • 0Altmetric
Article
A Low-Affinity Serum Response Element Allows Other Transcription Factors To Activate Inducible Gene Expression in Cardiac Myocytes
Wirt A. Hines, Jacqueline Thorburn & Andrew Thorburn
Pages: 1841-1852
Published online: 27 Mar 2023
AbstractforA Low-Affinity Serum Response Element Allows Other Transcription Factors To Activate Inducible Gene Expression in Cardiac Myocytes | Full Text | References | PDF (819 KB)
  • 12 Views
  • 22 CrossRef citations
  • 0Altmetric
Article
Telomerase Activity Is Sufficient To Allow Transformed Cells To Escape from Crisis
Tanya L. Halvorsen, Gil Leibowitz & Fred Levine
Pages: 1864-1870
Published online: 27 Mar 2023
AbstractforTelomerase Activity Is Sufficient To Allow Transformed Cells To Escape from Crisis | Full Text | References | PDF (1.1 MB)
  • 29 Views
  • 122 CrossRef citations
  • 0Altmetric
Article
Phosphorylation of the Cap-Binding Protein Eukaryotic Translation Initiation Factor 4E by Protein Kinase Mnk1 In Vivo
Andrew Jan Waskiewicz, Jeffrey C. Johnson, Bennett Penn, Malathy Mahalingam, Scot R. Kimball & Jonathan A. Cooper
Pages: 1871-1880
Published online: 27 Mar 2023
AbstractforPhosphorylation of the Cap-Binding Protein Eukaryotic Translation Initiation Factor 4E by Protein Kinase Mnk1 In Vivo | Full Text | References | PDF (1.1 MB)
  • 78 Views
  • 373 CrossRef citations
  • 0Altmetric
Article
Signals from the Ras, Rac, and Rho GTPases Converge on the Pak Protein Kinase in Rat-1 Fibroblasts
Yi Tang, Jong Yu & Jeffrey Field
Pages: 1881-1891
Published online: 27 Mar 2023
AbstractforSignals from the Ras, Rac, and Rho GTPases Converge on the Pak Protein Kinase in Rat-1 Fibroblasts | Full Text | References | PDF (3.3 MB)
  • 49 Views
  • 112 CrossRef citations
  • 0Altmetric
Article
Control of Growth and Differentiation by Drosophila RasGAP, a Homolog of p120 Ras–GTPase-Activating Protein
Pascale Feldmann, Eva N. Eicher, Sally J. Leevers, Ernst Hafen & David A. Hughes
Pages: 1928-1937
Published online: 27 Mar 2023
AbstractforControl of Growth and Differentiation by Drosophila RasGAP, a Homolog of p120 Ras–GTPase-Activating Protein | Full Text | References | PDF (1.9 MB)
  • 17 Views
  • 24 CrossRef citations
  • 0Altmetric
Article
The Jun Kinase 2 Isoform Is Preferentially Required for Epidermal Growth Factor-Induced Transformation of Human A549 Lung Carcinoma Cells
Frédéric Bost, Robert McKay, Myriam Bost, Olga Potapova, Nicholas M. Dean & Dan Mercola
Pages: 1938-1949
Published online: 27 Mar 2023
AbstractforThe Jun Kinase 2 Isoform Is Preferentially Required for Epidermal Growth Factor-Induced Transformation of Human A549 Lung Carcinoma Cells | Full Text | References | PDF (884.2 KB)
  • 20 Views
  • 114 CrossRef citations
  • 0Altmetric
Article
Reactive Oxygen Intermediate-Dependent NF-κB Activation by Interleukin-1β Requires 5-Lipoxygenase or NADPH Oxidase Activity
Giuseppina Bonizzi, Jacques Piette, Sonia Schoonbroodt, Roland Greimers, Laurence Havard, Marie-Paule Merville & Vincent Bours
Pages: 1950-1960
Published online: 27 Mar 2023
AbstractforReactive Oxygen Intermediate-Dependent NF-κB Activation by Interleukin-1β Requires 5-Lipoxygenase or NADPH Oxidase Activity | Full Text | References | PDF (1.6 MB)
  • 11 Views
  • 177 CrossRef citations
  • 0Altmetric
Article
Neu Differentiation Factor Stimulates Phosphorylation and Activation of the Sp1 Transcription Factor
Iris Alroy, Lior Soussan, Rony Seger & Yosef Yarden
Pages: 1961-1972
Published online: 27 Mar 2023
AbstractforNeu Differentiation Factor Stimulates Phosphorylation and Activation of the Sp1 Transcription Factor | Full Text | References | PDF (2.2 MB)
  • 9 Views
  • 74 CrossRef citations
  • 0Altmetric
Article
All-trans-Retinoic Acid Inhibits Jun N-Terminal Kinase by Increasing Dual-Specificity Phosphatase Activity
Ho-Young Lee, Naoko Sueoka, Waun-Ki Hong, David J. Mangelsdorf, Francois X. Claret & Jonathan M. Kurie
Pages: 1973-1980
Published online: 27 Mar 2023
AbstractforAll-trans-Retinoic Acid Inhibits Jun N-Terminal Kinase by Increasing Dual-Specificity Phosphatase Activity | Full Text | References | PDF (955.5 KB)
  • 11 Views
  • 80 CrossRef citations
  • 0Altmetric
Article
Induced Expression of p16INK4a Inhibits Both CDK4- and CDK2-Associated Kinase Activity by Reassortment of Cyclin-CDK-Inhibitor Complexes
Beth B. McConnell, Fiona J. Gregory, Francesca J. Stott, Eiji Hara & Gordon Peters
Pages: 1981-1989
Published online: 27 Mar 2023
AbstractforInduced Expression of p16INK4a Inhibits Both CDK4- and CDK2-Associated Kinase Activity by Reassortment of Cyclin-CDK-Inhibitor Complexes | Full Text | References | PDF (4.2 MB)
  • 60 Views
  • 167 CrossRef citations
  • 0Altmetric
Article
The Mitogen-Activated Protein Kinase Signaling Pathway Stimulates Mos mRNA Cytoplasmic Polyadenylation during Xenopus Oocyte Maturation
Emily L. Howard, Amanda Charlesworth, Joseph Welk & Angus M. MacNicol
Pages: 1990-1999
Published online: 27 Mar 2023
AbstractforThe Mitogen-Activated Protein Kinase Signaling Pathway Stimulates Mos mRNA Cytoplasmic Polyadenylation during Xenopus Oocyte Maturation | Full Text | References | PDF (919.3 KB)
  • 27 Views
  • 67 CrossRef citations
  • 0Altmetric
Article
In Vivo Chaperone Activity of Heat Shock Protein 70 and Thermotolerance
Ellen A. A. Nollen, Jeanette F. Brunsting, Han Roelofsen, Lee A. Weber & Harm H. Kampinga
Pages: 2069-2079
Published online: 27 Mar 2023
AbstractforIn Vivo Chaperone Activity of Heat Shock Protein 70 and Thermotolerance | Full Text | References | PDF (1.8 MB)
  • 41 Views
  • 160 CrossRef citations
  • 0Altmetric
Article
Activation-Dependent Transcriptional Regulation of the Human fas Promoter Requires NF-κB p50-p65 Recruitment
Henry Chan, David P. Bartos & Laurie B. Owen-Schaub
Pages: 2098-2108
Published online: 27 Mar 2023
AbstractforActivation-Dependent Transcriptional Regulation of the Human fas Promoter Requires NF-κB p50-p65 Recruitment | Full Text | References | PDF (1.3 MB)
  • 19 Views
  • 174 CrossRef citations
  • 0Altmetric
Article
Differential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts
Gretchen H. Stein, Linda F. Drullinger, Alexandre Soulard & Vjekoslav Dulić
Pages: 2109-2117
Published online: 27 Mar 2023
AbstractforDifferential Roles for Cyclin-Dependent Kinase Inhibitors p21 and p16 in the Mechanisms of Senescence and Differentiation in Human Fibroblasts | Full Text | References | PDF (1.8 MB)
  • 536 Views
  • 572 CrossRef citations
  • 0Altmetric
Article
SWM1, a Developmentally Regulated Gene, Is Required for Spore Wall Assembly in Saccharomyces cerevisiae
Sandra Ufano, Pedro San-Segundo, Francisco del Rey & Carlos R. Vázquez de Aldana
Pages: 2118-2129
Published online: 27 Mar 2023
AbstractforSWM1, a Developmentally Regulated Gene, Is Required for Spore Wall Assembly in Saccharomyces cerevisiae | Full Text | References | PDF (4.2 MB)
  • 10 Views
  • 22 CrossRef citations
  • 0Altmetric
Article
Different Regulation of the p53 Core Domain Activities 3′-to-5′ Exonuclease and Sequence-Specific DNA Binding
Friedemann Janus, Nils Albrechtsen, Uwe Knippschild, Lisa Wiesmüller, Frank Grosse & Wolfgang Deppert
Pages: 2155-2168
Published online: 27 Mar 2023
AbstractforDifferent Regulation of the p53 Core Domain Activities 3′-to-5′ Exonuclease and Sequence-Specific DNA Binding | Full Text | References | PDF (4.4 MB)
  • 3 Views
  • 36 CrossRef citations
  • 0Altmetric
Article
Reduced Phosphorylation of p50 Is Responsible for Diminished NF-κB Binding to the Major Histocompatibility Complex Class I Enhancer in Adenovirus Type 12-Transformed Cells
David B. Kushner & Robert P. Ricciardi
Pages: 2169-2179
Published online: 27 Mar 2023
AbstractforReduced Phosphorylation of p50 Is Responsible for Diminished NF-κB Binding to the Major Histocompatibility Complex Class I Enhancer in Adenovirus Type 12-Transformed Cells | Full Text | References | PDF (778 KB)
  • 2 Views
  • 32 CrossRef citations
  • 0Altmetric
Article
Activation of IκB Kinase β by Protein Kinase C Isoforms
Maria-José Lallena, María T. Diaz-Meco, Gary Bren, Carlos V. Payá & Jorge Moscat
Pages: 2180-2188
Published online: 27 Mar 2023
AbstractforActivation of IκB Kinase β by Protein Kinase C Isoforms | Full Text | References | PDF (1.7 MB)
  • 21 Views
  • 291 CrossRef citations
  • 0Altmetric
Article
The Caenorhabditis elegans Sex Determination Gene mog-1 Encodes a Member of the DEAH-Box Protein Family
Alessandro Puoti & Judith Kimble
Pages: 2189-2197
Published online: 27 Mar 2023
AbstractforThe Caenorhabditis elegans Sex Determination Gene mog-1 Encodes a Member of the DEAH-Box Protein Family | Full Text | References | PDF (954 KB)
  • 17 Views
  • 57 CrossRef citations
  • 0Altmetric
Article
Mutations of Oncoprotein 18/Stathmin Identify Tubulin-Directed Regulatory Activities Distinct from Tubulin Association
Niklas Larsson, Bo Segerman, Helena Melander Gradin, Ewa Wandzioch, Lynne Cassimeris & Martin Gullberg
Pages: 2242-2250
Published online: 27 Mar 2023
AbstractforMutations of Oncoprotein 18/Stathmin Identify Tubulin-Directed Regulatory Activities Distinct from Tubulin Association | Full Text | References | PDF (1 MB)
  • 4 Views
  • 33 CrossRef citations
  • 0Altmetric
Article
Progesterone Inhibits Estrogen-Induced Cyclin D1 and cdk4 Nuclear Translocation, Cyclin E- and Cyclin A-cdk2 Kinase Activation, and Cell Proliferation in Uterine Epithelial Cells in Mice
Wei Tong & Jeffrey W. Pollard
Pages: 2251-2264
Published online: 27 Mar 2023
AbstractforProgesterone Inhibits Estrogen-Induced Cyclin D1 and cdk4 Nuclear Translocation, Cyclin E- and Cyclin A-cdk2 Kinase Activation, and Cell Proliferation in Uterine Epithelial Cells in Mice | Full Text | References | PDF (2.6 MB)
  • 42 Views
  • 120 CrossRef citations
  • 0Altmetric
Article
Identification of a Novel Family of Targets of PYK2 Related to Drosophila Retinal Degeneration B (rdgB) Protein
Sima Lev, John Hernandez, Ricardo Martinez, Alon Chen, Greg Plowman & Joseph Schlessinger
Pages: 2278-2288
Published online: 27 Mar 2023
AbstractforIdentification of a Novel Family of Targets of PYK2 Related to Drosophila Retinal Degeneration B (rdgB) Protein | Full Text | References | PDF (1.9 MB)
  • 25 Views
  • 110 CrossRef citations
  • 0Altmetric
Article
The Wilms’ Tumor Suppressor Gene (wt1) Product Regulates Dax-1 Gene Expression during Gonadal Differentiation
Jungho Kim, Dirk Prawitt, Nabeel Bardeesy, Elena Torban, Caroline Vicaner, Paul Goodyer, Bernard Zabel & Jerry Pelletier
Pages: 2289-2299
Published online: 27 Mar 2023
AbstractforThe Wilms’ Tumor Suppressor Gene (wt1) Product Regulates Dax-1 Gene Expression during Gonadal Differentiation | Full Text | References | PDF (1.5 MB)
  • 22 Views
  • 106 CrossRef citations
  • 0Altmetric
Article
Requirement for Transcription Factor NFAT in Interleukin-2 Expression
Chi-Wing Chow, Mercedes Rincón & Roger J. Davis
Pages: 2300-2307
Published online: 27 Mar 2023
AbstractforRequirement for Transcription Factor NFAT in Interleukin-2 Expression | Full Text | References | PDF (397.6 KB)
  • 75 Views
  • 153 CrossRef citations
  • 0Altmetric
Article
Down-Regulation of RpS21, a Putative Translation Initiation Factor Interacting with P40, Produces Viable Minute Imagos and Larval Lethality with Overgrown Hematopoietic Organs and Imaginal Discs
István Török, Daniela Herrmann-Horle, István Kiss, Gabriela Tick, Gábor Speer, Rolf Schmitt & Bernard M. Mechler
Pages: 2308-2321
Published online: 27 Mar 2023
AbstractforDown-Regulation of RpS21, a Putative Translation Initiation Factor Interacting with P40, Produces Viable Minute Imagos and Larval Lethality with Overgrown Hematopoietic Organs and Imaginal Discs | Full Text | References | PDF (2 MB)
  • 33 Views
  • 40 CrossRef citations
  • 0Altmetric
Article
p38 Mitogen-Activated Protein Kinase Can Be Involved in Transforming Growth Factor β Superfamily Signal Transduction in Drosophila Wing Morphogenesis
Takashi Adachi-Yamada, Makoto Nakamura, Kenji Irie, Yoshinori Tomoyasu, Yorikata Sano, Eiji Mori, Satoshi Goto, Naoto Ueno, Yasuyoshi Nishida & Kunihiro Matsumoto
Pages: 2322-2329
Published online: 27 Mar 2023
Abstractforp38 Mitogen-Activated Protein Kinase Can Be Involved in Transforming Growth Factor β Superfamily Signal Transduction in Drosophila Wing Morphogenesis | Full Text | References | PDF (2.2 MB)
  • 72 Views
  • 137 CrossRef citations
  • 0Altmetric
Article
DEF-1, a Novel Src SH3 Binding Protein That Promotes Adipogenesis in Fibroblastic Cell Lines
Frederick J. King, Erding Hu, David F. Harris, Pasha Sarraf, Bruce M. Spiegelman & Thomas M. Roberts
Pages: 2330-2337
Published online: 27 Mar 2023
AbstractforDEF-1, a Novel Src SH3 Binding Protein That Promotes Adipogenesis in Fibroblastic Cell Lines | Full Text | References | PDF (1.2 MB)
  • 17 Views
  • 34 CrossRef citations
  • 0Altmetric
Article
Identification of a New Pyk2 Target Protein with Arf-GAP Activity
J. Andreev, J.-P. Simon, D. D. Sabatini, J. Kam, G. Plowman, P. A. Randazzo & J. Schlessinger
Pages: 2338-2350
Published online: 27 Mar 2023
AbstractforIdentification of a New Pyk2 Target Protein with Arf-GAP Activity | Full Text | References | PDF (4.8 MB)
  • 28 Views
  • 141 CrossRef citations
  • 0Altmetric
Article
Functions of Cyclin A1 in the Cell Cycle and Its Interactions with Transcription Factor E2F-1 and the Rb Family of Proteins
Rong Yang, Carsten Müller, Vong Huynh, Yuen K. Fung, Amy S. Yee & H. Phillip Koeffler
Pages: 2400-2407
Published online: 27 Mar 2023
AbstractforFunctions of Cyclin A1 in the Cell Cycle and Its Interactions with Transcription Factor E2F-1 and the Rb Family of Proteins | Full Text | References | PDF (3.3 MB)
  • 55 Views
  • 105 CrossRef citations
  • 0Altmetric
Article
The Yeast Ser/Thr Phosphatases Sit4 and Ppz1 Play Opposite Roles in Regulation of the Cell Cycle
Josep Clotet, Eloi Garí, Martí Aldea & Joaquín Ariño
Pages: 2408-2415
Published online: 27 Mar 2023
AbstractforThe Yeast Ser/Thr Phosphatases Sit4 and Ppz1 Play Opposite Roles in Regulation of the Cell Cycle | Full Text | References | PDF (1.1 MB)
  • 9 Views
  • 65 CrossRef citations
  • 0Altmetric
Article
Shp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway
Min You, De-Hua Yu & Gen-Sheng Feng
Pages: 2416-2424
Published online: 27 Mar 2023
AbstractforShp-2 Tyrosine Phosphatase Functions as a Negative Regulator of the Interferon-Stimulated Jak/STAT Pathway | Full Text | References | PDF (2.7 MB)
  • 101 Views
  • 256 CrossRef citations
  • 0Altmetric
Article
The LIM-Only Protein PINCH Directly Interacts with Integrin-Linked Kinase and Is Recruited to Integrin-Rich Sites in Spreading Cells
Yizeng Tu, Fugang Li, Silvia Goicoechea & Chuanyue Wu
Pages: 2425-2434
Published online: 27 Mar 2023
AbstractforThe LIM-Only Protein PINCH Directly Interacts with Integrin-Linked Kinase and Is Recruited to Integrin-Rich Sites in Spreading Cells | Full Text | References | PDF (893.1 KB)
  • 34 Views
  • 234 CrossRef citations
  • 0Altmetric

Dna Dynamics and Chromosome Structure

Article
Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin
France Carrier, Philippe T. Georgel, Philippe Pourquier, Mellissa Blake, H. Udo Kontny, Michael J. Antinore, Marzia Gariboldi, Timothy G. Myers, John N. Weinstein, Yves Pommier & Albert J. Fornace Jr.
Pages: 1673-1685
Published online: 27 Mar 2023
AbstractforGadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin | Full Text | References | PDF (1.9 MB)
  • 35 Views
  • 204 CrossRef citations
  • 0Altmetric
Article
Human Topoisomerase I Promotes Initiation of Simian Virus 40 DNA Replication In Vitro
Pamela W. Trowbridge, Rupa Roy & Daniel T. Simmons
Pages: 1686-1694
Published online: 27 Mar 2023
AbstractforHuman Topoisomerase I Promotes Initiation of Simian Virus 40 DNA Replication In Vitro | Full Text | References | PDF (1.3 MB)
  • 1 Views
  • 29 CrossRef citations
  • 0Altmetric
Article
The Saccharomyces cerevisiae ETH1 Gene, an Inducible Homolog of Exonuclease III That Provides Resistance to DNA-Damaging Agents and Limits Spontaneous Mutagenesis
Richard A. O. Bennett
Pages: 1800-1809
Published online: 27 Mar 2023
AbstractforThe Saccharomyces cerevisiae ETH1 Gene, an Inducible Homolog of Exonuclease III That Provides Resistance to DNA-Damaging Agents and Limits Spontaneous Mutagenesis | Full Text | References | PDF (868.8 KB)
  • 14 Views
  • 57 CrossRef citations
  • 0Altmetric
Article
The 3′→5′ Exonucleases of DNA Polymerases δ and ɛ and the 5′→3′ Exonuclease Exo1 Have Major Roles in Postreplication Mutation Avoidance in Saccharomyces cerevisiae
Hiep T. Tran, Dmitry A. Gordenin & Michael A. Resnick
Pages: 2000-2007
Published online: 27 Mar 2023
AbstractforThe 3′→5′ Exonucleases of DNA Polymerases δ and ɛ and the 5′→3′ Exonuclease Exo1 Have Major Roles in Postreplication Mutation Avoidance in Saccharomyces cerevisiae | Full Text | References | PDF (112.7 KB)
  • 31 Views
  • 170 CrossRef citations
  • 0Altmetric
Article
Impaired Translesion Synthesis in Xeroderma Pigmentosum Variant Extracts
Agnes M. Cordonnier, Alan R. Lehmann & Robert P. P. Fuchs
Pages: 2206-2211
Published online: 27 Mar 2023
AbstractforImpaired Translesion Synthesis in Xeroderma Pigmentosum Variant Extracts | Full Text | References | PDF (1.1 MB)
  • 18 Views
  • 62 CrossRef citations
  • 0Altmetric
Article
A New Member of the Sin3 Family of Corepressors Is Essential for Cell Viability and Required for Retroelement Propagation in Fission Yeast
Van Dinh Dang, Michael J. Benedik, Karl Ekwall, Jeannie Choi, Robin C. Allshire & Henry L. Levin
Pages: 2351-2365
Published online: 27 Mar 2023
AbstractforA New Member of the Sin3 Family of Corepressors Is Essential for Cell Viability and Required for Retroelement Propagation in Fission Yeast | Full Text | References | PDF (3.5 MB)
  • 14 Views
  • 26 CrossRef citations
  • 0Altmetric
Article
Postnatal Growth Failure, Short Life Span, and Early Onset of Cellular Senescence and Subsequent Immortalization in Mice Lacking the Xeroderma Pigmentosum Group G Gene
Yoshi-Nobu Harada, Naoko Shiomi, Manabu Koike, Masahito Ikawa, Masaru Okabe, Seiichi Hirota, Yukihiko Kitamura, Masanobu Kitagawa, Tsukasa Matsunaga, Osamu Nikaido & Tadahiro Shiomi
Pages: 2366-2372
Published online: 27 Mar 2023
AbstractforPostnatal Growth Failure, Short Life Span, and Early Onset of Cellular Senescence and Subsequent Immortalization in Mice Lacking the Xeroderma Pigmentosum Group G Gene | Full Text | References | PDF (1 MB)
  • 15 Views
  • 96 CrossRef citations
  • 0Altmetric
Article
Analysis of Genomic Integrity and p53-Dependent G1Checkpoint in Telomerase-Induced Extended-Life-Span Human Fibroblasts
Homayoun Vaziri, Jeremy A. Squire, Tej K. Pandita, Grace Bradley, Robert M. Kuba, Haihua Zhang, Sandor Gulyas, Richard P. Hill, Garry P. Nolan & Samuel Benchimol
Pages: 2373-2379
Published online: 27 Mar 2023
AbstractforAnalysis of Genomic Integrity and p53-Dependent G1Checkpoint in Telomerase-Induced Extended-Life-Span Human Fibroblasts | Full Text | References | PDF (4.4 MB)
  • 10 Views
  • 78 CrossRef citations
  • 0Altmetric

Cell and Organelle Structure and Assembly

Article
Hsp60 Is Targeted to a Cryptic Mitochondrion-Derived Organelle (“Crypton”) in the Microaerophilic Protozoan Parasite Entamoeba histolytica
Zhiming Mai, Sudip Ghosh, Marta Frisardi, Ben Rosenthal, Rick Rogers & John Samuelson
Pages: 2198-2205
Published online: 27 Mar 2023
AbstractforHsp60 Is Targeted to a Cryptic Mitochondrion-Derived Organelle (“Crypton”) in the Microaerophilic Protozoan Parasite Entamoeba histolytica | Full Text | References | PDF (2 MB)
  • 15 Views
  • 148 CrossRef citations
  • 0Altmetric
Article
Identification and Characterization of the Human Orthologue of Yeast Pex14p
Garnet K. Will, Monika Soukupova, Xinji Hong, Kai S. Erdmann, Jan A. K. W. Kiel, Gabriele Dodt, Wolf-Hubert Kunau & Ralf Erdmann
Pages: 2265-2277
Published online: 27 Mar 2023
AbstractforIdentification and Characterization of the Human Orthologue of Yeast Pex14p | Full Text | References | PDF (1.3 MB)
  • 14 Views
  • 94 CrossRef citations
  • 0Altmetric

Explore articles

Explore the most recently published articles

Regulation of T Cell Signaling and Immune Responses by PTPN22
Rebecca J. Brownlie et al.
Review Article | Published online: 22 Jul 2024
Open Access
ELF5-Regulated lncRNA-TTN-AS1 Alleviates Myocardial Cell Injury via Recruiting PCBP2 to Increase CDK6 Stability in Myocardial Infarction
Yonglin Zhang et al.
Article | Published online: 21 Jul 2024
Transcription Factor 23 is an Essential Determinant of Murine Term Parturition
Fatma M. Minisy et al.
Article | Published online: 16 Jul 2024
Expression of Interferon Epsilon in Mucosal Epithelium is Regulated by Elf3
Ka Yee Fung et al.
Article | Published online: 8 Jul 2024
View all latest articles