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DNA Dynamics and Chromosome Structure

The 3′→5′ Exonucleases of DNA Polymerases δ and ɛ and the 5′→3′ Exonuclease Exo1 Have Major Roles in Postreplication Mutation Avoidance in Saccharomyces cerevisiae

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Pages 2000-2007 | Received 01 Jul 1998, Accepted 18 Nov 1998, Published online: 27 Mar 2023

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Basanta K. Dahal, Lyudmila Y. Kadyrova, Kristin R. Delfino, Igor B. Rogozin, Vaibhavi Gujar, Kirill S. Lobachev & Farid A. Kadyrov. (2017) Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae. PLOS Genetics 13:10, pages e1007074.
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Dekang Liu, Jane H. Frederiksen, Sascha E. Liberti, Anne Lützen, Guido Keijzers, Javier Pena-Diaz & Lene Juel Rasmussen. (2017) Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro. Nucleic Acids Research 45:16, pages 9427-9440.
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Stephanie R. Barbari & Polina V. Shcherbakova. (2017) Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for therapy. DNA Repair 56, pages 16-25.
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Dekang Liu, Guido Keijzers & Lene Juel Rasmussen. (2017) DNA mismatch repair and its many roles in eukaryotic cells. Mutation Research/Reviews in Mutation Research 773, pages 174-187.
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Tobias T. SchmidtGloria ReyesKerstin GriesCemile Ümran CeylanSushma SharmaMatthias MeurerMichael KnopAndrei Chabes & Hans Hombauer. (2017) Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis . Proceedings of the National Academy of Sciences 114:22.
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Daniel G. Dennis, Jill McKay-Fleisch, Kaila Eitzen, Ian Dowsett, Scott R. Kennedy & Alan J. Herr. (2017) Normally lethal amino acid substitutions suppress an ultramutator DNA Polymerase δ variant. Scientific Reports 7:1.
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Nikki BowenRichard D. Kolodner. (2017) Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins . Proceedings of the National Academy of Sciences 114:14, pages 3607-3612.
Crossref
Lyudmila Y. Kadyrova, Basanta K. Dahal & Farid A. Kadyrov. (2016) The Major Replicative Histone Chaperone CAF-1 Suppresses the Activity of the DNA Mismatch Repair System in the Cytotoxic Response to a DNA-methylating Agent. Journal of Biological Chemistry 291:53, pages 27298-27312.
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Rais A. Ganai, Xiao-Ping Zhang, Wolf-Dietrich Heyer & Erik Johansson. (2016) Strand displacement synthesis by yeast DNA polymerase ε. Nucleic Acids Research 44:17, pages 8229-8240.
Crossref
Rais A. Ganai & Erik Johansson. (2016) DNA Replication—A Matter of Fidelity. Molecular Cell 62:5, pages 745-755.
Crossref
Emily Rayner, Inge C. van Gool, Claire Palles, Stephen E. Kearsey, Tjalling Bosse, Ian Tomlinson & David N. Church. (2016) A panoply of errors: polymerase proofreading domain mutations in cancer. Nature Reviews Cancer 16:2, pages 71-81.
Crossref
Lyudmila Y. Kadyrova & Farid A. Kadyrov. (2016) Endonuclease activities of MutLα and its homologs in DNA mismatch repair. DNA Repair 38, pages 42-49.
Crossref
Gray F. Crouse. (2016) Non-canonical actions of mismatch repair. DNA Repair 38, pages 102-109.
Crossref
Richard D. Kolodner. (2016) A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair. DNA Repair 38, pages 3-13.
Crossref
S.A. Martin. 2016. DNA Repair in Cancer Therapy. DNA Repair in Cancer Therapy 151 177 .
Yi LiaoJeremy W. Schroeder, Burke GaoLyle A. Simmons & Julie S. Biteen. (2015) Single-molecule motions and interactions in live cells reveal target search dynamics in mismatch repair. Proceedings of the National Academy of Sciences 112:50.
Crossref
Gloria X. Reyes, Tobias T. Schmidt, Richard D. Kolodner & Hans Hombauer. (2015) New insights into the mechanism of DNA mismatch repair. Chromosoma 124:4, pages 443-462.
Crossref
Thomas A. KunkelDorothy A. Erie. (2015) Eukaryotic Mismatch Repair in Relation to DNA Replication. Annual Review of Genetics 49:1, pages 291-313.
Crossref
Lyudmila Y. Kadyrova, Basanta K. Dahal & Farid A. Kadyrov. (2015) Evidence That the DNA Mismatch Repair System Removes 1-Nucleotide Okazaki Fragment Flaps. Journal of Biological Chemistry 290:40, pages 24051-24065.
Crossref
Maren F. Hansen, Jostein Johansen, Inga Bjørnevoll, Anna E. Sylvander, Kristin S. Steinsbekk, Pål Sætrom, Arne K. Sandvik, Finn Drabløs & Wenche Sjursen. (2015) A novel POLE mutation associated with cancers of colon, pancreas, ovaries and small intestine. Familial Cancer 14:3, pages 437-448.
Crossref
Catherine E. Smith, Nikki Bowen, William J. GrahamVV, Eva M. Goellner, Anjana Srivatsan & Richard D. Kolodner. (2015) Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System. Journal of Biological Chemistry 290:35, pages 21580-21590.
Crossref
A. M. Mahedi Hasan & David R. F. Leach. (2015) Chromosomal directionality of DNA mismatch repair in Escherichia coli . Proceedings of the National Academy of Sciences 112:30, pages 9388-9393.
Crossref
Robert E. Johnson, Roland Klassen, Louise Prakash & Satya Prakash. (2015) A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands. Molecular Cell 59:2, pages 163-175.
Crossref
Jordan A. St Charles, Sascha E. Liberti, Jessica S. Williams, Scott A. Lujan & Thomas A. Kunkel. (2015) Quantifying the contributions of base selectivity, proofreading and mismatch repair to nuclear DNA replication in Saccharomyces cerevisiae. DNA Repair 31, pages 41-51.
Crossref
Lindsey N. Williams, Lisette Marjavaara, Gary M. Knowels, Eric M. Schultz, Edward J. Fox, Andrei Chabes & Alan J. Herr. (2015) dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variants. Proceedings of the National Academy of Sciences 112:19.
Crossref
Hariyanto Darmawan, Melissa Harrison & Linda J. Reha-Krantz. (2015) DNA polymerase 3′→5′ exonuclease activity: Different roles of the beta hairpin structure in family-B DNA polymerases. DNA Repair 29, pages 36-46.
Crossref
Scott R. Kennedy, Eric M. Schultz, Thomas M. Chappell, Brendan Kohrn, Gary M. Knowels & Alan J. Herr. (2015) Volatility of Mutator Phenotypes at Single Cell Resolution. PLOS Genetics 11:4, pages e1005151.
Crossref
Carrie L. Flood, Gina P. Rodriguez, Gaobin Bao, Arthur H. Shockley, Yoke Wah Kow & Gray F. Crouse. (2015) Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans. PLOS Genetics 11:3, pages e1005049.
Crossref
Rais A. Ganai, Pia Osterman & Erik Johansson. (2015) Yeast DNA Polymerase ϵ Catalytic Core and Holoenzyme Have Comparable Catalytic Rates. Journal of Biological Chemistry 290:6, pages 3825-3835.
Crossref
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Crossref
Eva M. Goellner, Catherine E. Smith, Christopher S. Campbell, Hans Hombauer, Arshad Desai, Christopher D. Putnam & Richard D. Kolodner. (2014) PCNA and Msh2-Msh6 Activate an Mlh1-Pms1 Endonuclease Pathway Required for Exo1-Independent Mismatch Repair. Molecular Cell 55:2, pages 291-304.
Crossref
Fei Ma, Yong Yang & Chun-yang Zhang. (2014) Ultrasensitive Detection of Transcription Factors Using Transcription-Mediated Isothermally Exponential Amplification-Induced Chemiluminescence. Analytical Chemistry 86:12, pages 6006-6011.
Crossref
Ewa Grabowska, Urszula Wronska, Milena Denkiewicz, Malgorzata Jaszczur, Aleksandra Respondek, Malgorzata Alabrudzinska, Catherine Suski, Karolina Makiela‐Dzbenska, Piotr Jonczyk & Iwona J. Fijalkowska. (2014) Proper functioning of the GINS complex is important for the fidelity of DNA replication in yeast . Molecular Microbiology 92:4, pages 659-680.
Crossref
Erin E. Henninger & Zachary F. Pursell. (2014) DNA polymerase ε and its roles in genome stability. IUBMB Life 66:5, pages 339-351.
Crossref
Lyudmila Y. Kadyrova, Tony M. Mertz, Yu Zhang, Matthew R. Northam, Ziwei Sheng, Kirill S. Lobachev, Polina V. Shcherbakova & Farid A. Kadyrov. (2013) A Reversible Histone H3 Acetylation Cooperates with Mismatch Repair and Replicative Polymerases in Maintaining Genome Stability. PLoS Genetics 9:10, pages e1003899.
Crossref
David N. Church, Sarah E.W. Briggs, Claire Palles, Enric Domingo, Stephen J. Kearsey, Jonathon M. Grimes, Maggie Gorman, Lynn Martin, Kimberley M. Howarth, Shirley V. Hodgson, Kulvinder Kaur, Jenny Taylor & Ian P.M. Tomlinson. (2013) DNA polymerase ɛ and δ exonuclease domain mutations in endometrial cancer. Human Molecular Genetics 22:14, pages 2820-2828.
Crossref
Scott A. Lujan, Jessica S. Williams, Anders R. Clausen, Alan B. Clark & Thomas A. Kunkel. (2013) Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors. Molecular Cell 50:3, pages 437-443.
Crossref
Serge Boiteux & Sue Jinks-Robertson. (2013) DNA Repair Mechanisms and the Bypass of DNA Damage in Saccharomyces cerevisiae . Genetics 193:4, pages 1025-1064.
Crossref
Celina Galles & Claudia P. Spampinato. (2012) Yeast mutator phenotype enforced by Arabidopsis PMS1 expression. Molecular Biology Reports 40:3, pages 2107-2114.
Crossref
Ruth I. Tennen, Joanna E. Haye, Hashanthi D. Wijayatilake, Tim Arlow, Danielle Ponzio & Alison E. Gammie. (2013) Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level. DNA Repair 12:2, pages 97-109.
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Sascha E. Liberti, Andres A. Larrea & Thomas A. Kunkel. (2013) Exonuclease 1 preferentially repairs mismatches generated by DNA polymerase α. DNA Repair 12:2, pages 92-96.
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Penelope A. Mason & Lynne S. Cox. (2011) The role of DNA exonucleases in protecting genome stability and their impact on ageing. AGE 34:6, pages 1317-1340.
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Irina S.-R. Waisertreiger, Victoria G. Liston, Miriam R. Menezes, Hyun-Min Kim, Kirill S. Lobachev, Elena I. Stepchenkova, Tahir H. Tahirov, Igor B. Rogozin & Youri I. Pavlov. (2012) Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools. Environmental and Molecular Mutagenesis 53:9, pages 699-724.
Crossref
Dongmei Zheng, Ruxing Zou & Xinhui Lou. (2012) Label-Free Fluorescent Detection of Ions, Proteins, and Small Molecules Using Structure-Switching Aptamers, SYBR Gold, and Exonuclease I. Analytical Chemistry 84:8, pages 3554-3560.
Crossref
Scott R. Kennedy, Lawrence A. Loeb & Alan J. Herr. (2012) Somatic mutations in aging, cancer and neurodegeneration. Mechanisms of Ageing and Development 133:4, pages 118-126.
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Min Yuan, Yonggang Zhu, Xinhui Lou, Chen Chen, Gang Wei, Minbo Lan & Jianlong Zhao. (2012) Sensitive label-free oligonucleotide-based microfluidic detection of mercury (II) ion by using exonuclease I. Biosensors and Bioelectronics 31:1, pages 330-336.
Crossref
Hans Hombauer, Christopher S. Campbell, Catherine E. Smith, Arshad Desai & Richard D. Kolodner. (2011) Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates. Cell 147:5, pages 1040-1053.
Crossref
Alan J. Herr, Masanori Ogawa, Nicole A. Lawrence, Lindsey N. Williams, Julie M. Eggington, Mallika Singh, Robert A. Smith & Bradley D. Preston. (2011) Mutator Suppression and Escape from Replication Error–Induced Extinction in Yeast. PLoS Genetics 7:10, pages e1002282.
Crossref
Charanya Kumar, Sarah C. Piacente, Justin Sibert, Andrew R. Bukata, Jaime O'Connor, Eric Alani & Jennifer A. Surtees. (2011) Multiple Factors Insulate Msh2–Msh6 Mismatch Repair Activity from Defects in Msh2 Domain I. Journal of Molecular Biology 411:4, pages 765-780.
Crossref
D. A. Korona, K. G. LeCompte & Z. F. Pursell. (2010) The high fidelity and unique error signature of human DNA polymerase  . Nucleic Acids Research 39:5, pages 1763-1773.
Crossref
Anna Aksenova, Kirill Volkov, Jaroslaw Maceluch, Zachary F. Pursell, Igor B. Rogozin, Thomas A. Kunkel, Youri I. Pavlov & Erik Johansson. (2010) Mismatch Repair–Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of DNA Polymerase ε. PLoS Genetics 6:11, pages e1001209.
Crossref
Bradley D. Preston, Tina M. Albertson & Alan J. Herr. (2010) DNA replication fidelity and cancer. Seminars in Cancer Biology 20:5, pages 281-293.
Crossref
Clémentine Brocas, Jean-Baptiste Charbonnier, Claudine Dhérin, Serge Gangloff & Laurent Maloisel. (2010) Stable interactions between DNA polymerase δ catalytic and structural subunits are essential for efficient DNA repair. DNA Repair 9:10, pages 1098-1111.
Crossref
Linda J. Reha-Krantz. (2010) DNA polymerase proofreading: Multiple roles maintain genome stability. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1804:5, pages 1049-1063.
Crossref
Tina M. AlbertsonMasanori OgawaJames M. BugniLaura E. HaysYang ChenYanping WangPiper M. Treuting, John A. HeddleRobert E. Goldsby & Bradley D. Preston. (2009) DNA polymerase ε and δ proofreading suppress discrete mutator and cancer phenotypes in mice. Proceedings of the National Academy of Sciences 106:40, pages 17101-17104.
Crossref
Claudia P. Spampinato, Rodrigo L. Gomez, Celina Galles & Luciana D. Lario. (2009) From bacteria to plants: A compendium of mismatch repair assays. Mutation Research/Reviews in Mutation Research 682:2-3, pages 110-128.
Crossref
Heqiao Dai, Jianying Liu, Linda H. Malkas, Jennifer Catalano, Srilakshmi Alagharu & Robert J. Hickey. (2009) Chromium reduces the in vitro activity and fidelity of DNA replication mediated by the human cell DNA synthesome. Toxicology and Applied Pharmacology 236:2, pages 154-165.
Crossref
Alvaro Galli, Kurt Hafer, Tiziana Cervelli & Robert H. Schiestl. (2009) The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent . Journal of Biomedicine and Biotechnology 2009, pages 1-9.
Crossref
Mengmeng Yang, Stuart G. Jarrett, Rolf Craven & David M. Kaetzel. (2009) YNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 660:1-2, pages 74-78.
Crossref
Peggy Hsieh & Kazuhiko Yamane. (2008) DNA mismatch repair: Molecular mechanism, cancer, and ageing. Mechanisms of Ageing and Development 129:7-8, pages 391-407.
Crossref
Scott D McCulloch & Thomas A Kunkel. (2008) The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Research 18:1, pages 148-161.
Crossref
Zachary F. Pursell & Thomas A. Kunkel. 2008. 101 145 .
M Kucherlapati, A Nguyen, M Kuraguchi, K Yang, K Fan, R Bronson, K Wei, M Lipkin, W Edelmann & R Kucherlapati. (2007) Tumor progression in Apc1638N mice with Exo1 and Fen1 deficiencies. Oncogene 26:43, pages 6297-6306.
Crossref
Paul Modrich. (2006) Mechanisms in Eukaryotic Mismatch Repair. Journal of Biological Chemistry 281:41, pages 30305-30309.
Crossref
Francisco J. López de Saro, Martin G. Marinus, Paul Modrich & Mike O'Donnell. (2006) The β Sliding Clamp Binds to Multiple Sites within MutL and MutS. Journal of Biological Chemistry 281:20, pages 14340-14349.
Crossref
Josef Jiricny. (2006) The multifaceted mismatch-repair system. Nature Reviews Molecular Cell Biology 7:5, pages 335-346.
Crossref
Kelly Murphy, Hariyanto Darmawan, Amy Schultz, Elizabeth Fidalgo da Silva & Linda J Reha-Krantz. (2006) A method to select for mutator DNA polymerase δs in Saccharomyces cerevisiae . Genome 49:4, pages 403-410.
Crossref
Sung-Hoon Jun, Tae Gyun Kim & Changill Ban. (2006) DNA mismatch repair system. Classical and fresh roles. FEBS Journal 273:8, pages 1609-1619.
Crossref
Tohru Daikoku, Ayumi Kudoh, Yutaka Sugaya, Satoko Iwahori, Noriko Shirata, Hiroki Isomura & Tatsuya Tsurumi. (2006) Postreplicative Mismatch Repair Factors Are Recruited to Epstein-Barr Virus Replication Compartments. Journal of Biological Chemistry 281:16, pages 11422-11430.
Crossref
Amy Abdulovic, Nayun Kim & Sue Jinks-Robertson. (2006) Mutagenesis and the three R's in yeast. DNA Repair 5:4, pages 409-421.
Crossref
Tina M. Albertson & Bradley D. Preston. (2006) DNA Replication Fidelity: Proofreading in Trans. Current Biology 16:6, pages R209-R211.
Crossref
Ravi R. Iyer, Anna Pluciennik, Vickers Burdett & Paul L. Modrich. (2005) DNA Mismatch Repair:  Functions and Mechanisms. Chemical Reviews 106:2, pages 302-323.
Crossref
Y.I. Pavlov, C. Frahm, S.A. Nick McElhinny, A. Niimi, M. Suzuki & T.A. Kunkel. (2006) Evidence that Errors Made by DNA Polymerase α are Corrected by DNA Polymerase δ. Current Biology 16:2, pages 202-207.
Crossref
Youri I. Pavlov, Polina V. Shcherbakova & Igor B. Rogozin. 2006. A Survey of Cell Biology. A Survey of Cell Biology 41 132 .
Nicoleta Constantin, Leonid Dzantiev, Farid A. Kadyrov & Paul Modrich. (2005) Human Mismatch Repair. Journal of Biological Chemistry 280:48, pages 39752-39761.
Crossref
P LAUN, L RAMACHANDRAN, S JAROLIM, E HERKER, P LIANG, J WANG, M WEINBERGER, D BURHANS, B SUTER & F MADEO. (2005) A comparison of the aging and apoptotic transcriptome of. FEMS Yeast Research 5:12, pages 1261-1272.
Crossref
Errol C. Friedberg, Graham C. Walker, Wolfram Siede, Richard D. Wood, Roger A. Schultz & Tom Ellenberger. 2005. DNA Repair and Mutagenesis. DNA Repair and Mutagenesis 389 447 .
Petr Cejka, Nina Mojas, Ludovic Gillet, Primo Schär & Josef Jiricny. (2005) Homologous Recombination Rescues Mismatch-Repair-Dependent Cytotoxicity of SN1-Type Methylating Agents in S. cerevisiae. Current Biology 15:15, pages 1395-1400.
Crossref
Lei Li, Kelly M Murphy, Uliana Kanevets & Linda J Reha-Krantz. (2005) Sensitivity to Phosphonoacetic Acid. Genetics 170:2, pages 569-580.
Crossref
Thomas A. KunkelDorothy A. Erie. (2005) DNA MISMATCH REPAIR. Annual Review of Biochemistry 74:1, pages 681-710.
Crossref
Anthony T Vo, Fengxue Zhu, Xiling Wu, Fenghua Yuan, Yin Gao, Liya Gu, Guo‐Min Li, Tai‐Hsien Lee & Chengtao Her. (2005) hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair. EMBO reports 6:5, pages 438-444.
Crossref
Giancarlo Marra & Josef Jiricny. 2005. Genome Instability in Cancer Development. Genome Instability in Cancer Development 85 123 .
Phuoc T. Tran, Naz Erdeniz, Lorraine S. Symington & R.Michael Liskay. (2004) EXO1-A multi-tasking eukaryotic nuclease. DNA Repair 3:12, pages 1549-1559.
Crossref
I.V. Fedorova, S.V. Kovaltzova, L.M. Gracheva, T.A. Evstuhina & V.G. Korolev. (2004) Requirement of HSM3 gene for spontaneous mutagenesis in Saccharomyces cerevisiae. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 554:1-2, pages 67-75.
Crossref
Sascha Emilie Liberti & Lene Juel Rasmussen. (2004) Is hEXO1 a Cancer Predisposing Gene? . Molecular Cancer Research 2:8, pages 427-432.
Crossref
L Kevin Lewis, Francesca Storici, Stephen Van Komen, Shanna Calero, Patrick Sung & Michael A Resnick. (2004) Role of the Nuclease Activity of Saccharomyces cerevisiae Mre11 in Repair of DNA Double-Strand Breaks in Mitotic Cells . Genetics 166:4, pages 1701-1713.
Crossref
Shuangli Guo, Steven R. Presnell, Fenghua Yuan, Yanbin Zhang, Liya Gu & Guo-Min Li. (2004) Differential Requirement for Proliferating Cell Nuclear Antigen in 5′ and 3′ Nick-directed Excision in Human Mismatch Repair. Journal of Biological Chemistry 279:17, pages 16912-16917.
Crossref
Finn Cilius Nielsen, Anne Charlotte Jäger, Anne Lützen, Jens R Bundgaard & Lene Juel Rasmussen. (2003) Characterization of human exonuclease 1 in complex with mismatch repair proteins, subcellular localization and association with PCNA. Oncogene 23:7, pages 1457-1468.
Crossref
N.A. Alam, P. Gorman, E.E.M. Jaeger, D. Kelsell, I.M. Leigh, R. Ratnavel, M.E. Murdoch, R.S. Houlston, L.A. Aaltonen, R.R. Roylance & I.P.M. Tomlinson. (2003) Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability. Cancer Genetics and Cytogenetics 147:2, pages 121-127.
Crossref
Mark J. SchofieldPeggy Hsieh. (2003) DNA Mismatch Repair: Molecular Mechanisms and Biological Function. Annual Review of Microbiology 57:1, pages 579-608.
Crossref
Polina V. Shcherbakova, Youri I. Pavlov, Olga Chilkova, Igor B. Rogozin, Erik Johansson & Thomas A. Kunkel. (2003) Unique Error Signature of the Four-subunit Yeast DNA Polymerase ϵ. Journal of Biological Chemistry 278:44, pages 43770-43780.
Crossref
Yong Hwan Jin, Alan B Clark, Robbert J C Slebos, Hanan Al-Refai, Jack A Taylor, Thomas A Kunkel, Michael A Resnick & Dmitry A Gordenin. (2003) Cadmium is a mutagen that acts by inhibiting mismatch repair. Nature Genetics 34:3, pages 326-329.
Crossref
Alvaro Galli, Tiziana Cervelli & Robert H Schiestl. (2003) Characterization of the Hyperrecombination Phenotype of the pol3-t Mutation of Saccharomyces cerevisiae . Genetics 164:1, pages 65-79.
Crossref
Kaichun Wei, Alan B. Clark, Edmund Wong, Michael F. Kane, Dan J. Mazur, Tchaiko Parris, Nadine K. Kolas, Robert Russell, Harry HouJr.Jr., Burkhard Kneitz, Guohze Yang, Thomas A. Kunkel, Richard D. Kolodner, Paula E. Cohen & Winfried Edelmann. (2003) Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes & Development 17:5, pages 603-614.
Crossref
Polina V. ShcherbakovaKatarzyna BebenekThomas A. Kunkel. (2003) Functions of Eukaryotic DNA Polymerases. Science of Aging Knowledge Environment 2003:8.
Crossref
Phuoc T Tran, Naz Erdeniz, Sandra Dudley & R.Michael Liskay. (2002) Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae. DNA Repair 1:11, pages 895-912.
Crossref
Huixian Wang & John B. Hays. (2002) Mismatch Repair in Human Nuclear Extracts. Journal of Biological Chemistry 277:29, pages 26143-26148.
Crossref
Kaichun Wei, Raju Kucherlapati & Winfried Edelmann. (2002) Mouse models for human DNA mismatch-repair gene defects. Trends in Molecular Medicine 8:7, pages 346-353.
Crossref
Ulrich HübscherGiovanni MagaSilvio Spadari. (2002) Eukaryotic DNA Polymerases. Annual Review of Biochemistry 71:1, pages 133-163.
Crossref
Igor V. Shevelev & Ulrich Hübscher. (2002) The 3′–5′ exonucleases. Nature Reviews Molecular Cell Biology 3:5, pages 364-376.
Crossref
Jochen Genschel, Laura R. Bazemore & Paul Modrich. (2002) Human Exonuclease I Is Required for 5′ and 3′ Mismatch Repair. Journal of Biological Chemistry 277:15, pages 13302-13311.
Crossref
Thomas M. Marti, Christophe Kunz & Oliver Fleck. (2002) DNA mismatch repair and mutation avoidance pathways. Journal of Cellular Physiology 191:1, pages 28-41.
Crossref
Juan Lucas Argueso, Daniel Smith, James Yi, Marc Waase, Sumeet Sarin & Eric Alani. (2002) Analysis of Conditional Mutations in the Saccharomyces cerevisiae MLH1 Gene in Mismatch Repair and in Meiotic Crossing Over . Genetics 160:3, pages 909-921.
Crossref
L Kevin Lewis, G Karthikeyan, James W Westmoreland & Michael A Resnick. (2002) Differential Suppression of DNA Repair Deficiencies of Yeast rad50 , mre11 and xrs2 Mutants by EXO1 and TLC1 (the RNA Component of Telomerase) . Genetics 160:1, pages 49-62.
Crossref
Sandrine Jacob & Françoise Praz. (2002) DNA mismatch repair defects: role in colorectal carcinogenesis. Biochimie 84:1, pages 27-47.
Crossref
Marta Szadkowski & Josef Jiricny. (2002) Identification and functional characterization of the promoter region of the humanMSH6 gene. Genes, Chromosomes and Cancer 33:1, pages 36-46.
Crossref
Suzanne E. Berry & Timothy J. Kinsella. (2001) Targeting DNA mismatch repair for radiosensitization. Seminars in Radiation Oncology 11:4, pages 300-315.
Crossref
Christopher N Greene & Sue Jinks-Robertson. (2001) Spontaneous Frameshift Mutations in Saccharomyces cerevisiae : Accumulation During DNA Replication and Removal by Proofreading and Mismatch Repair Activities . Genetics 159:1, pages 65-75.
Crossref
Phuoc T. Tran, Jeffrey A. Simon & R. Michael Liskay. (2001) Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae . Proceedings of the National Academy of Sciences 98:17, pages 9760-9765.
Crossref
Christoph Schmutte, Margaret M. Sadoff, Kang-Sup Shim, Samir Acharya & Richard Fishel. (2001) The Interaction of DNA Mismatch Repair Proteins with Human Exonuclease I. Journal of Biological Chemistry 276:35, pages 33011-33018.
Crossref
Peggy Hsieh. (2001) Molecular mechanisms of DNA mismatch repair. Mutation Research/DNA Repair 486:2, pages 71-87.
Crossref
Aylin Rizki & Victoria Lundblad. (2001) Defects in mismatch repair promote telomerase-independent proliferation. Nature 411:6838, pages 713-716.
Crossref
Vickers Burdett, Celia Baitinger, Mohan Viswanathan, Susan T. Lovett & Paul Modrich. (2001) In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair . Proceedings of the National Academy of Sciences 98:12, pages 6765-6770.
Crossref
Yong Hwan Jin, Robyn Obert, Peter M. J. Burgers, Thomas A. Kunkel, Michael A. Resnick & Dmitry A. Gordenin. (2001) The 3′→5′ exonuclease of DNA polymerase δ can substitute for the 5′ flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability. Proceedings of the National Academy of Sciences 98:9, pages 5122-5127.
Crossref
Jayson Bowers, Phuoc T Tran, Amita Joshi, R.Michael Liskay & Eric Alani. (2001) MSH-MLH complexes formed at a DNA mismatch are disrupted by the PCNA sliding clamp. Journal of Molecular Biology 306:5, pages 957-968.
Crossref
Brian D HarfeSue Jinks-Robertson. (2000) DNA MISMATCH REPAIR AND GENETIC INSTABILITY. Annual Review of Genetics 34:1, pages 359-399.
Crossref
B. S. Strauss, R. Roberts, L. Francis & P. Pouryazdanparast. (2000) Role of the dinB Gene Product in Spontaneous Mutation in Escherichia coli with an Impaired Replicative Polymerase . Journal of Bacteriology 182:23, pages 6742-6750.
Crossref
Alan B. Clark, Frank Valle, Karin Drotschmann, Ronald K. Gary & Thomas A. Kunkel. (2000) Functional Interaction of Proliferating Cell Nuclear Antigen with MSH2-MSH6 and MSH2-MSH3 Complexes. Journal of Biological Chemistry 275:47, pages 36498-36501.
Crossref
Abhijit Datta, James L. Schmeits, Neelam S. Amin, Patrick J. Lau, Kyungjae Myung & Richard D. Kolodner. (2000) Checkpoint-Dependent Activation of Mutagenic Repair in Saccharomyces cerevisiae pol3-01 Mutants. Molecular Cell 6:3, pages 593-603.
Crossref
J M Kirchner, H Tran & M A Resnick. (2000) A DNA Polymerase ε Mutant That Specifically Causes +1 Frameshift Mutations Within Homonucleotide Runs in Yeast. Genetics 155:4, pages 1623-1632.
Crossref
Kirill S. Lobachev, Judith E. Stenger, Olga G. Kozyreva, Jerzy Jurka, Dmitry A. Gordenin & Michael A. Resnick. (2000) Inverted Alu repeats unstable in yeast are excluded from the human genome . The EMBO Journal 19:14, pages 3822-3830.
Crossref
Tanya Sokolsky & Eric Alani. (2000) EXO1 and MSH6 Are High-Copy Suppressors of Conditional Mutations in the MSH2 Mismatch Repair Gene of Saccharomyces cerevisiae . Genetics 155:2, pages 589-599.
Crossref
Brian D Harfe & Sue Jinks-Robertson. (2000) Mismatch repair proteins and mitotic genome stability. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 451:1-2, pages 151-167.
Crossref
Karin Drotschmann, Polina V Shcherbakova & Thomas A Kunkel. (2000) Mutator phenotype due to loss of heterozygosity in diploid yeast strains with mutations in MSH2 and MLH1. Toxicology Letters 112-113, pages 239-244.
Crossref
Ainsley Nicholson, Miyono Hendrix, Sue Jinks-Robertson & Gray F Crouse. (2000) Regulation of Mitotic Homeologous Recombination in Yeast: Functions of Mismatch Repair and Nucleotide Excision Repair Genes. Genetics 154:1, pages 133-146.
Crossref
Ravi R. Iyer, Anna Pluciennik, William A. Rosche, Richard R. Sinden & Robert D. Wells. (2000) DNA Polymerase III Proofreading Mutants Enhance the Expansion and Deletion of Triplet Repeat Sequences in Escherichia coli. Journal of Biological Chemistry 275:3, pages 2174-2184.
Crossref
Manuel Stucki, Igor Stagljar, Zophonias O. Jonsson & Ulrich Hübscher. 2000. 261 298 .
Andrew B. Buermeyer, Suzanne M. Deschênes, Sean M. Baker & R. Michael Liskay. (1999) Mammalian DNA Mismatch Repair. Annual Review of Genetics 33:1, pages 533-564.
Crossref
A. L. Greene, J. R. Snipe, D. A. Gordenin & M. A. Resnick. (1999) Functional Analysis of Human FEN1 in Saccharomyces Cerevisiae and Its Role in Genome Stability. Human Molecular Genetics 8:12, pages 2263-2273.
Crossref
Hiep T Tran, Natasha P Degtyareva, Dmitry A Gordenin & Michael A Resnick. (1999) Genetic Factors Affecting the Impact of DNA Polymerase ∂ Proofreading Activity on Mutation Avoidance in Yeast. Genetics 152:1, pages 47-59.
Crossref
Richard D Kolodner & Gerald T Marsischky. (1999) Eukaryotic DNA mismatch repair. Current Opinion in Genetics & Development 9:1, pages 89-96.
Crossref

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