34
Views
234
CrossRef citations to date
0
Altmetric
Cell Growth and Development

The LIM-Only Protein PINCH Directly Interacts with Integrin-Linked Kinase and Is Recruited to Integrin-Rich Sites in Spreading Cells

, , &
Pages 2425-2434 | Received 31 Aug 1998, Accepted 11 Dec 1998, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (10)

Yong-Chul Kim, Reyda Gonzalez-Nieves & Mary L Cutler. (2015) Rsu1 contributes to cell adhesion and spreading in MCF10A cells via effects on P38 map kinase signaling. Cell Adhesion & Migration 9:3, pages 227-232.
Read now
Derek L. Clouthier, Cameron N. Harris, Richard A. Harris, Claire E. Martin, Mira C. Puri & Nina Jones. (2015) Requisite Role for Nck Adaptors in Cardiovascular Development, Endothelial-to-Mesenchymal Transition, and Directed Cell Migration. Molecular and Cellular Biology 35:9, pages 1573-1587.
Read now
Grant A. Howe & Christina L. Addison. (2012) β1 integrin. Cell Adhesion & Migration 6:2, pages 71-77.
Read now
Benjamin Meder, Inken G. Huttner, Farbod Sedaghat-Hamedani, Steffen Just, Tillman Dahme, Karen S. Frese, Britta Vogel, Doreen Köhler, Wanda Kloos, Jessica Rudloff, Sabine Marquart, Hugo A. Katus & Wolfgang Rottbauer. (2011) PINCH Proteins Regulate Cardiac Contractility by Modulating Integrin-Linked Kinase-Protein Kinase B Signaling. Molecular and Cellular Biology 31:16, pages 3424-3435.
Read now
Haiyan Chu, Ingo Thievessen, Michael Sixt, Tim Lämmermann, Ari Waisman, Attila Braun, Angelika A. Noegel & Reinhard Fässler. (2006) γ-Parvin Is Dispensable for Hematopoiesis, Leukocyte Trafficking, and T-Cell-Dependent Antibody Response. Molecular and Cellular Biology 26:5, pages 1817-1825.
Read now
Emerson Liu, Sumita Sinha, Christine Williams, Marcoli Cyrille, Eric Heller, Scott B. Snapper, Katia Georgopoulos, Rene St-Arnaud, Thomas Force, Shoukat Dedhar & Robert E. Gerszten. (2005) Targeted Deletion of Integrin-Linked Kinase Reveals a Role in T-Cell Chemotaxis and Survival. Molecular and Cellular Biology 25:24, pages 11145-11155.
Read now
Chungyee Leung-Hagesteijn, Ming Chang Hu, Ahalya S. Mahendra, Sunny Hartwig, Henry J. Klamut, Norman D. Rosenblum & Gregory E. Hannigan. (2005) Integrin-Linked Kinase Mediates Bone Morphogenetic Protein 7-Dependent Renal Epithelial Cell Morphogenesis. Molecular and Cellular Biology 25:9, pages 3648-3657.
Read now
Xingqun Liang, Qiang Zhou, Xiaodong Li, Yunfu Sun, Min Lu, Nancy Dalton, John Ross$suffix/text()$suffix/text() & Ju Chen. (2005) PINCH1 Plays an Essential Role in Early Murine Embryonic Development but Is Dispensable in Ventricular Cardiomyocytes. Molecular and Cellular Biology 25:8, pages 3056-3062.
Read now
Alison A. Hill & Paul R. Riley. (2004) Differential Regulation of Hand1 Homodimer and Hand1-E12 Heterodimer Activity by the Cofactor FHL2. Molecular and Cellular Biology 24:22, pages 9835-9847.
Read now

Articles from other publishers (224)

Jingling Zhao, Shuai Yang, Yingbin Xu, Shitian Qin, Fan Bie, Lei Chen, Fei Zhou, Julin Xie, Xusheng Liu, Bin Shu & Shaohai Qi. (2023) Mechanical pressure-induced dedifferentiation of myofibroblasts inhibits scarring via SMYD3/ITGBL1 signaling. Developmental Cell 58:13, pages 1139-1152.e6.
Crossref
Xiaohao Wu, Sixiong Lin, Rongdong Liao, Qing Yao, Lijun Lin, Xuenong Zou & Guozhi Xiao. (2023) Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice. Frontiers in Cell and Developmental Biology 11.
Crossref
Qian Wang, Pengfei Yu, Chaoxu Liu, Xianli He & Gang Wang. (2022) Mitochondrial fragmentation in liver cancer: Emerging player and promising therapeutic opportunities. Cancer Letters 549, pages 215912.
Crossref
Salvatore Condello, Mayuri Prasad, Rula Atwani & Daniela Matei. (2022) Tissue transglutaminase activates integrin-linked kinase and β-catenin in ovarian cancer. Journal of Biological Chemistry 298:8, pages 102242.
Crossref
Joana Paes de Faria, Raquel S. Vale-Silva, Reinhard Fässler, Hauke B. Werner & João B. Relvas. (2022) Pinch2 regulates myelination in the mouse central nervous system. Development 149:13.
Crossref
Claudia Tanja Mierke, Alexander Hayn & Tony Fischer. (2022) PINCH1 Promotes Fibroblast Migration in Extracellular Matrices and Influences Their Mechanophenotype. Frontiers in Cell and Developmental Biology 10.
Crossref
Lijie Shi, Silvia E Racedo, Alexander Diacou, Taeju Park, Bin Zhou & Bernice E Morrow. (2022) Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation . Human Molecular Genetics 31:8, pages 1197-1215.
Crossref
Marie-Louise Bang, Julius Bogomolovas & Ju Chen. (2022) Understanding the molecular basis of cardiomyopathy. American Journal of Physiology-Heart and Circulatory Physiology 322:2, pages H181-H233.
Crossref
Agata Górska & Antonina Joanna Mazur. (2022) Integrin-linked kinase (ILK): the known vs. the unknown and perspectives. Cellular and Molecular Life Sciences 79:2.
Crossref
Chunhong Cui, Jiaxin Wang, Ling Guo & Chuanyue Wu. (2021) PINCH-1 promotes Δ1-pyrroline-5-carboxylate synthase expression and contributes to proline metabolic reprogramming in lung adenocarcinoma. Amino Acids 53:12, pages 1875-1890.
Crossref
Keng Chen, Ling Guo & Chuanyue Wu. (2021) How signaling pathways link extracellular mechano‐environment to proline biosynthesis: A hypothesis. BioEssays 43:9, pages 2100116.
Crossref
Saleh Almasabi, Afsar U. Ahmed, Richard Boyd & Bryan R. G. Williams. (2021) A Potential Role for Integrin-Linked Kinase in Colorectal Cancer Growth and Progression via Regulating Senescence and Immunity. Frontiers in Genetics 12.
Crossref
Jie Su, Ling Guo & Chuanyue Wu. (2021) A mechanoresponsive PINCH-1-Notch2 interaction regulates smooth muscle differentiation of human placental mesenchymal stem cells. Stem Cells 39:5, pages 650-668.
Crossref
Meiling Wang, Jie Liu, Yizeng Tu, Zihan Zhao, Jingjing Qu, Ka Chen, Yonglong Chen, Ying Sun, Hui Zhao, Yi Deng & Chuanyue Wu. (2021) RSU-1 interaction with prohibitin-2 links cell–extracellular matrix detachment to downregulation of ERK signaling. Journal of Biological Chemistry 296, pages 100109.
Crossref
Keng Chen, Yilin Wang, Xiaoying Deng, Ling Guo & Chuanyue Wu. (2021) Extracellular matrix stiffness regulates mitochondrial dynamics through PINCH-1- and kindlin-2-mediated signalling. Current Research in Cell Biology 2, pages 100008.
Crossref
Kalimuthusamy Natarajaseenivasan, Santhanam Shanmughapriya, Prema Velusamy, Matthew Sayre, Alvaro Garcia, Nestor Mas Gomez & Dianne Langford. (2020) Inflammation-induced PINCH expression leads to actin depolymerization and mitochondrial mislocalization in neurons. Translational Neurodegeneration 9:1.
Crossref
Ekene Emmanuel Nweke, Previn Naicker, Shaun Aron, Stoyan Stoychev, John Devar, David L. Tabb, Jones Omoshoro-Jones, Martin Smith & Geoffrey Candy. (2020) SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways. PLOS ONE 15:10, pages e0240453.
Crossref
Yiming Lei, Xuekun Fu, Pengyu Li, Sixiong Lin, Qinnan Yan, Yumei Lai, Xin Liu, Yishu Wang, Xiaochun Bai, Chuanju Liu, Di Chen, Xuenong Zou, Xu Cao, Huiling Cao & Guozhi Xiao. (2020) LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice. Bone Research 8:1.
Crossref
Ling Guo, Chunhong Cui, Jiaxin Wang, Jifan Yuan, Qingyang Yang, Ping Zhang, Wen Su, Ruolu Bao, Jingchao Ran & Chuanyue Wu. (2020) PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth. Nature Communications 11:1.
Crossref
Xinyan Wang, Shuai Huang, Cunni Zheng, Wei Ge, Chuanyue Wu & Yu Chung Tse. (2020) RSU-1 Maintains Integrity of Caenorhabditis elegans Vulval Muscles by Regulating α-Actinin . G3 Genes|Genomes|Genetics 10:7, pages 2507-2517.
Crossref
Maria Louca, Triantafyllos Stylianopoulos & Vasiliki Gkretsi. (2020) Ras Suppressor-1 (RSU1) in Cancer Cell Metastasis: A Tale of a Tumor Suppressor. International Journal of Molecular Sciences 21:11, pages 4076.
Crossref
Arica Beisaw, Carsten KuenneStefan GuentherJulia DallmannChi-Chung WuMette BentsenMario LoosoDidier Y.R. Stainier. (2020) AP-1 Contributes to Chromatin Accessibility to Promote Sarcomere Disassembly and Cardiomyocyte Protrusion During Zebrafish Heart Regeneration. Circulation Research 126:12, pages 1760-1778.
Crossref
Tao Qian, Chengmin Liu, Yanyan Ding, Chen Guo, Renwei Cai, Xiaoxia Wang, Rong Wang, Kuo Zhang, Li Zhou, Yi Deng, Chuanyue Wu & Ying Sun. (2019) PINCH-1 interacts with myoferlin to promote breast cancer progression and metastasis. Oncogene 39:10, pages 2069-2087.
Crossref
Yishu Wang, Qinnan Yan, Yiran Zhao, Xin Liu, Simin Lin, Peijun Zhang, Liting Ma, Yumei Lai, Xiaochun Bai, Chuanju Liu, Chuanyue Wu, Jian Q. Feng, Di Chen, Huiling Cao & Guozhi Xiao. (2019) Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice. JCI Insight 4:22.
Crossref
Ling Guo, Rong Wang, Kuo Zhang, Jifan Yuan, Jiaxin Wang, Xiaoxia Wang, Jianfei Ma & Chuanyue Wu. (2019) A PINCH-1–Smurf1 signaling axis mediates mechano-regulation of BMPR2 and stem cell differentiation. Journal of Cell Biology 218:11, pages 3773-3794.
Crossref
Marni D. Boppart & Ziad S. Mahmassani. (2019) Integrin signaling: linking mechanical stimulation to skeletal muscle hypertrophy. American Journal of Physiology-Cell Physiology 317:4, pages C629-C641.
Crossref
Hannah J. Green & Nicholas H. Brown. (2019) Integrin intracellular machinery in action. Experimental Cell Research 378:2, pages 226-231.
Crossref
Mohammed Alasseiri, Afsar U. Ahmed & Bryan R.G. Williams. (2018) Mechanisms and consequences of constitutive activation of integrin-linked kinase in acute myeloid leukemia. Cytokine & Growth Factor Reviews 43, pages 1-7.
Crossref
Chihiro Endo, Todd A. Johnson, Ryoko Morino, Kazuyuki Nakazono, Shigeo Kamitsuji, Masanori Akita, Maiko Kawajiri, Tatsuya Yamasaki, Azusa Kami, Yuria Hoshi, Asami Tada, Kenichi Ishikawa, Maaya Hine, Miki Kobayashi, Nami Kurume, Yuichiro Tsunemi, Naoyuki Kamatani & Makoto Kawashima. (2018) Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations. Scientific Reports 8:1.
Crossref
Georgios Tsinias, Sofia Nikou, Theodoros Papadas, Panagiotis Pitsos, Helen Papadaki & Vasiliki Bravou. (2018) High PINCH1 Expression in Human Laryngeal Carcinoma Associates with Poor Prognosis. Analytical Cellular Pathology 2018, pages 1-12.
Crossref
Archana Raman, Gail A. Reif, Yuqiao Dai, Aditi Khanna, Xiaogang Li, Lindsay Astleford, Stephen C. Parnell, James P. Calvet & Darren P. Wallace. (2017) Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease. Journal of the American Society of Nephrology 28:9, pages 2708-2719.
Crossref
Ellen Dickreuter & Nils Cordes. (2017) The cancer cell adhesion resistome: mechanisms, targeting and translational approaches. Biological Chemistry 398:7, pages 721-735.
Crossref
Aki Manninen & Markku Varjosalo. (2017) A proteomics view on integrin-mediated adhesions. PROTEOMICS 17:3-4, pages 1600022.
Crossref
Arthur ZimmermannArthur Zimmermann. 2017. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 3323 3350 .
Huamin Xu, Huiling Cao & Guozhi Xiao. (2016) Signaling via PINCH: Functions, binding partners and implications in human diseases. Gene 594:1, pages 10-15.
Crossref
Nicholas Rooney, Pengbo Wang, Keith Brennan, Andrew P. Gilmore & Charles H. Streuli. (2016) The Integrin‐Mediated ILK‐Parvin‐αPix Signaling Axis Controls Differentiation in Mammary Epithelial Cells. Journal of Cellular Physiology 231:11, pages 2408-2417.
Crossref
Laura A. New, Claire E. Martin, Rizaldy P. Scott, Mathew J. PlattAva Keyvani Chahi, Colin D. Stringer, Peihua Lu, Bozena Samborska, Vera EreminaTomoko Takano, Jeremy A. SimpsonSusan E. Quaggin & Nina Jones. (2016) Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture. Journal of the American Society of Nephrology 27:8, pages 2422-2435.
Crossref
P-C Chu, M-C Yang, S K Kulp, S B Salunke, L E Himmel, C-S Fang, A M Jadhav, Y-S Shan, C-T Lee, M-D Lai, L A Shirley, T Bekaii-Saab & C-S Chen. (2015) Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells. Oncogene 35:30, pages 3897-3908.
Crossref
Gang Li, Ye-Yang Li, Jing-En Sun, Wei-hua Lin & Ri-xing Zhou. (2016) ILK–PI3K/AKT pathway participates in cutaneous wound contraction by regulating fibroblast migration and differentiation to myofibroblast. Laboratory Investigation 96:7, pages 741-751.
Crossref
Shali Mazaki-Tovi, Adi L. Tarca, Edi Vaisbuch, Juan Pedro Kusanovic, Nandor Gabor Than, Tinnakorn Chaiworapongsa, Zhong Dong, Sonia S. Hassan & Roberto Romero. (2016) Characterization of visceral and subcutaneous adipose tissue transcriptome in pregnant women with and without spontaneous labor at term: implication of alternative splicing in the metabolic adaptations of adipose tissue to parturition. Journal of Perinatal Medicine 44:7.
Crossref
Rizaldy P. Scott & Susan E. Quaggin. 2016. Kidney Development, Disease, Repair and Regeneration. Kidney Development, Disease, Repair and Regeneration 103 119 .
Miriam de Fatima Brasil Engelman & Gustavo Gonçalves Engelman. 2016. Biomarkers in Kidney Disease. Biomarkers in Kidney Disease 991 1013 .
Arthur ZimmermannArthur Zimmermann. 2016. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1 28 .
Rizaldy P. Scott & Susan E. Quaggin. (2015) The cell biology of renal filtration. Journal of Cell Biology 209:2, pages 199-210.
Crossref
Miriam de Fatima Brasil Engelman & Gustavo Gonçalves Engelman. 2015. Biomarkers in Kidney Disease. Biomarkers in Kidney Disease 1 23 .
Rachel Lennon, Michael J. Randles & Martin J. Humphries. (2014) The Importance of Podocyte Adhesion for a Healthy Glomerulus. Frontiers in Endocrinology 5.
Crossref
Ho-Tak Lau, Hyong Won Suh, Martin Golkowski & Shao-En Ong. (2014) Comparing SILAC- and Stable Isotope Dimethyl-Labeling Approaches for Quantitative Proteomics. Journal of Proteome Research 13:9, pages 4164-4174.
Crossref
C.I. Jones, K.L. Tucker, P. Sasikumar, T. Sage, W.J. Kaiser, C. Moore, M. Emerson & J.M. Gibbins. (2014) Integrin‐linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi. Journal of Thrombosis and Haemostasis 12:8, pages 1342-1352.
Crossref
Jianguo Chen, Yifang Chen, Yunling Luo, Dingkun Gui, Jianhua Huang & Dongyuan He. (2014) Astragaloside IV ameliorates diabetic nephropathy involving protection of podocytes in streptozotocin induced diabetic rats. European Journal of Pharmacology 736, pages 86-94.
Crossref
Hidenori Kawashima, Aiko Obayashi, Marie Kawamura, Sakae Masaki, Satoshi Tamada, Taro Iguchi, Junji Uchida, Katsuyuki Kuratsukuri, Tomoaki Tanaka & Tatsuya Nakatani. (2014) Galectin 9 and PINCH, novel immunotherapy targets of renal cell carcinoma: a rationale to find potential tumour antigens and the resulting cytotoxic T lymphocytes induced by the derived peptides. BJU International 113:2, pages 320-332.
Crossref
Anastasia Eskova, Bettina Knapp, Dorota Matelska, Susanne Reusing, Antti Arjonen, Tautvydas Lisauskas, Rainer Pepperkok, Robert Russell, Roland Eils, Johanna Ivaska, Lars Kaderali, Holger Erfle & Vytaute Starkuviene. (2014) RNAi screen identifies KIF15 as a novel regulator of integrin endocytic trafficking. Journal of Cell Science.
Crossref
Shigenori Honda, Hiroko Shirotani-Ikejima, Seiji Tadokoro, Yoshiaki Tomiyama & Toshiyuki Miyata. (2013) The Integrin-Linked Kinase-PINCH-Parvin Complex Supports Integrin αIIbβ3 Activation. PLoS ONE 8:12, pages e85498.
Crossref
Masaaki Yoshigi, Stephen M Pronovost & Julie L Kadrmas. (2013) Interactions by 2D Gel Electrophoresis Overlap (iGEO): a novel high fidelity approach to identify constituents of protein complexes. Proteome Science 11:1.
Crossref
Reyda Gonzalez-Nieves, Akiko Iwahari DeSantis & Mary L. Cutler. (2013) Rsu1 contributes to regulation of cell adhesion and spreading by PINCH1-dependent and - independent mechanisms. Journal of Cell Communication and Signaling 7:4, pages 279-293.
Crossref
Santiago Roura, Carolina Gálvez-Montón, Josep M. Pujal, Laura Casani, Marco A. Fernández, Laura Astier, Paloma Gastelurrutia, Maite Domingo, Cristina Prat-Vidal, Carolina Soler-Botija, Aida Llucià-Valldeperas, Vicenta Llorente-Cortés & Antoni Bayes-Genis. (2013) New insights into lipid raft function regulating myocardial vascularization competency in human idiopathic dilated cardiomyopathy. Atherosclerosis 230:2, pages 354-364.
Crossref
Sushmita Ghatak, Jessica Morgner & Sara A. Wickström. (2013) ILK: a pseudokinase with a unique function in the integrin–actin linkage. Biochemical Society Transactions 41:4, pages 995-1001.
Crossref
Cecile Boscher & Ivan R. Nabi. (2013) Galectin-3– and phospho-caveolin-1–dependent outside-in integrin signaling mediates the EGF motogenic response in mammary cancer cells. Molecular Biology of the Cell 24:13, pages 2134-2145.
Crossref
Dongfeng Zeng, Lei Hao, Wei Xu, Zhihong Li, Weiyan Li, Jieping Li, Xi Zhang, Xinghua Chen & Peiyan Kong. (2012) Pinch-1 was up-regulated in leukemia BMSC and its possible effect. Clinical and Experimental Medicine 13:1, pages 21-27.
Crossref
Amy L. Stiegler, Thomas D. Grant, Joseph R. Luft, David A. Calderwood, Edward H. Snell & Titus J. Boggon. (2013) Purification and SAXS Analysis of the Integrin Linked Kinase, PINCH, Parvin (IPP) Heterotrimeric Complex. PLoS ONE 8:1, pages e55591.
Crossref
ZHEN-LONG ZHU, BAO-YONG YAN, YU ZHANG, YAN-HONG YANG, ZHENG-MIN WANG, HONG-ZHEN ZHANG, MING-WEI WANG, XIANG-HONG ZHANG & XIAO-FENG SUN. (2013) Cytoplasmic expression of p33ING1b is correlated with tumorigenesis and progression of human esophageal squamous cell carcinoma. Oncology Letters 5:1, pages 161-166.
Crossref
Chen-Hsien Liang, Szu-Ying Chiu, I-Ling Hsu, Yi-Ying Wu, Yao-Tsung Tsai, Jhen-Yu Ke, Szu-Hua Pan, Yi-Chiung Hsu, Ker-Chau Li, Pan-Chyr Yang, Yuh-Ling Chen & Tse-Ming Hong. (2013) α-Catulin Drives Metastasis by Activating ILK and Driving an αvβ3 Integrin Signaling Axis. Cancer Research 73:1, pages 428-438.
Crossref
Zhen-Long Zhu, Bao-Yong Yan, Yu Zhang, Yan-Hong Yang, Ming-Wei Wang, Hanswalter Zentgraf, Xiang-Hong Zhang & Xiao-Feng Sun. (2013) Overexpression of FXYD-3 Is Involved in the Tumorigenesis and Development of Esophageal Squamous Cell Carcinoma. Disease Markers 35, pages 195-202.
Crossref
Samar Sayedyahossein & Lina Dagnino. 2013. 321 354 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 465 646 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 387 463 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 379 386 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 311 378 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 175 310 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 137 173 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 109 135 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 7 107 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 911 918 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 821 909 .
Marc ThirietMarc Thiriet. 2013. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems. Intracellular Signaling Mediators in the Circulatory and Ventilatory Systems 647 819 .
Annica Holmqvist, Jingfang Gao, Birgitta Holmlund, Gunnar Adell, John Carstensen, Dianne Langford & Xiao-Feng Sun. (2012) PINCH is an independent prognostic factor in rectal cancer patients without preoperative radiotherapy - a study in a Swedish rectal cancer trial of preoperative radiotherapy. BMC Cancer 12:1.
Crossref
Jun Qin & Chuanyue Wu. (2012) ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling. Current Opinion in Cell Biology 24:5, pages 607-613.
Crossref
Yoon Pyo Choi, Baek Gil Kim, Ming-Qing Gao, Suki Kang & Nam Hoon Cho. (2012) Targeting ILK and β4 integrin abrogates the invasive potential of ovarian cancer. Biochemical and Biophysical Research Communications 427:3, pages 642-648.
Crossref
Eloi Montanez, Esra Karaköse, Denise Tischner, Andreas Villunger & Reinhard Fässler. (2012) PINCH-1 promotes Bcl-2-dependent survival signalling and inhibits JNK-mediated apoptosis in the primitive endoderm.. Journal of Cell Science.
Crossref
Maria C. Elias, Stephen M. Pronovost, Kinley J. Cahill, Mary C. Beckerle & Julie L. Kadrmas. (2012) A critical role for Ras Suppressor-1 (RSU-1) revealed when PINCH-Integrin-linked Kinase (ILK) binding is disrupted. Journal of Cell Science.
Crossref
Georg Kontaxis, Klaus Bister & Robert Konrat. 2011. Encyclopedia of Inorganic and Bioinorganic Chemistry. Encyclopedia of Inorganic and Bioinorganic Chemistry.
Mélissa Labelle-Côté, Julie Dusseault, Salma Ismaïl, Aude Picard-Cloutier, Peter M Siegel & Louise Larose. (2011) Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo. BMC Cancer 11:1.
Crossref
Jasmine Lööf, Johan Rosell, Charlotte Bratthäll, Siv Doré, Hans Starkhammar, Hong Zhang & Xiao-Feng Sun. (2011) Impact of PINCH expression on survival in colorectal cancer patients. BMC Cancer 11:1.
Crossref
Leena P. Desai, Yidi Wu, Robert S. Tepper & Susan J. Gunst. (2011) Mechanical stimuli and IL-13 interact at integrin adhesion complexes to regulate expression of smooth muscle myosin heavy chain in airway smooth muscle tissue. American Journal of Physiology-Lung Cellular and Molecular Physiology 301:3, pages L275-L284.
Crossref
Asavari Jatiani, Paola Pannizzo, Elisa Gualco, Luis Del-Valle & Dianne Langford. (2010) Neuronal PINCH is Regulated by TNF-α and is Required for Neurite Extension. Journal of Neuroimmune Pharmacology 6:3, pages 330-340.
Crossref
Nicholas Rooney & Charles H. Streuli. (2011) How integrins control mammary epithelial differentiation: A possible role for the ILK-PINCH-Parvin complex. FEBS Letters 585:11, pages 1663-1672.
Crossref
Christos G. Zervas, Eleni Psarra, Victoria Williams, Esther Solomon, Katerina M. Vakaloglou & Nicholas H. Brown. (2011) A central multifunctional role of integrin-linked kinase at muscle attachment sites. Journal of Cell Science 124:8, pages 1316-1327.
Crossref
Jane Kovalevich, Brittany Tracy & Dianne Langford. (2011) PINCH: More than just an adaptor protein in cellular response. Journal of Cellular Physiology 226:4, pages 940-947.
Crossref
Laura E. Phipps, Satoshi Hino & Ruth J. Muschel. (2011) Targeting Cell Spreading: A Method of Sensitizing Metastatic Tumor Cells to TRAIL-Induced Apoptosis. Molecular Cancer Research 9:3, pages 249-258.
Crossref
Dan Wang, Yingjian Li, Chuanyue Wu & Youhua Liu. (2011) PINCH1 Is Transcriptional Regulator in Podocytes That Interacts with WT1 and Represses Podocalyxin Expression. PLoS ONE 6:2, pages e17048.
Crossref
Mitra Esfandiarei, Sahar Abdoli Yazdi, Virginia Gray, Shoukat Dedhar & Cornelis van Breemen. (2010) Integrin-linked kinase functions as a downstream signal of platelet-derived growth factor to regulate actin polymerization and vascular smooth muscle cell migration. BMC Cell Biology 11:1.
Crossref
Satoko Ito, Yuko Takahara, Toshinori Hyodo, Hitoki Hasegawa, Eri Asano, Michinari Hamaguchi & Takeshi Senga. (2010) The Roles of Two Distinct Regions of PINCH-1 in the Regulation of Cell Attachment and Spreading. Molecular Biology of the Cell 21:23, pages 4120-4129.
Crossref
C-F Wu, K-F Ng, C-S Chen, P-L Chang, C-K Chuang, W-H Weng, S-K Liao & S-T Pang. (2010) Expression of parvin-β is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract. British Journal of Cancer 103:6, pages 852-860.
Crossref
S M Pontier, L Huck, D E White, J Rayment, V Sanguin-Gendreau, B Hennessy, D Zuo, R St-Arnaud, G B Mills, S Dedhar, C J Marshall & W J Muller. (2010) Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer. Oncogene 29:23, pages 3374-3385.
Crossref
Brian P. Chiswell, Amy L. Stiegler, Ziba Razinia, Elina Nalibotski, Titus J. Boggon & David A. Calderwood. (2010) Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase. Journal of Structural Biology 170:1, pages 157-163.
Crossref
Sara A Wickström, Anika Lange, Eloi Montanez & Reinhard Fässler. (2009) The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!. The EMBO Journal 29:2, pages 281-291.
Crossref
Paul C. McDonald & Shoukat Dedhar. 2010. Cell-Extracellular Matrix Interactions in Cancer. Cell-Extracellular Matrix Interactions in Cancer 245 273 .
Xingqun Liang, Yunfu SunJu Chen. (2023) Particularly Interesting Cysteine- and Histidine-Rich Protein in Cardiac Development and Remodeling. Journal of Investigative Medicine 57:8, pages 842-848.
Crossref
Giorgio Petricca, Mari Leppilampi, Guoqiao Jiang, Gethin R. Owen, Colin Wiebe, Yizeng Tu, Leeni Koivisto, Lari Häkkinen, Chuanyue Wu & Hannu Larjava. (2009) Localization and potential function of kindlin-1 in periodontal tissues. European Journal of Oral Sciences 117:5, pages 518-527.
Crossref
Yingjian Li, Xiaoyue Tan, Chunsun Dai, Donna B. Stolz, Dan Wang & Youhua Liu. (2009) Inhibition of Integrin-Linked Kinase Attenuates Renal Interstitial Fibrosis. Journal of the American Society of Nephrology 20:9, pages 1907-1918.
Crossref
Katherine L. Tucker, William J. Kaiser, Angela L. Bergeron, Hongbo Hu, Jing-fei Dong, Tse-Hua Tan & Jonathan M. Gibbins. (2009) Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets. PROTEOMICS 9:18, pages 4340-4354.
Crossref
Jinbu WangXiaobing ZuoPing YuIn-Ja L. ByeonJinwon JungXiaoxia WangMarzena DybaSoenke SeifertCharles D. SchwietersJun QinAngela M. GronenbornYun-Xing Wang. (2009) Determination of Multicomponent Protein Structures in Solution Using Global Orientation and Shape Restraints. Journal of the American Chemical Society 131:30, pages 10507-10515.
Crossref
Hans Schotman, Leena Karhinen & Catherine Rabouille. (2009) Integrins mediate their unconventional, mechanical-stress-induced secretion via RhoA and PINCH in Drosophila . Journal of Cell Science 122:15, pages 2662-2672.
Crossref
Judy Wai Ping Yam, Edith Yuk Ting Tse & Irene Oi-Lin Ng. (2009) Role and significance of focal adhesion proteins in hepatocellular carcinoma. Journal of Gastroenterology and Hepatology 24:4, pages 520-530.
Crossref
Mariam AlexanderKevin Ka Ming ChanAlexandra B. ByrneGuillermo SelmanTeresa LeeJasmine OnoEric WongRachel PuckrinScott J. DixonPeter John Roy. (2009) An UNC-40 pathway directs postsynaptic membrane extension in Caenorhabditis elegans . Development 136:6, pages 911-922.
Crossref
Joel Cerna Cortés, Eliud Alfredo Garcia Montalvo, Jesús Muñiz, Dominique Mornet, Efrain Garrido, Federico Centeno & Bulmaro Cisneros. (2008) Dp71f Modulates GSK3-β Recruitment to the β1-Integrin Adhesion Complex. Neurochemical Research 34:3, pages 438-444.
Crossref
Yanwu Yang, Xiaoxia Wang, Cheryl A. Hawkins, Kan Chen, Julia Vaynberg, Xian Mao, Yizeng Tu, Xiaobing Zuo, Jinbu Wang, Yun-xing Wang, Chuanyue Wu, Nico Tjandra & Jun Qin. (2009) Structural Basis of Focal Adhesion Localization of LIM-only Adaptor PINCH by Integrin-linked Kinase. Journal of Biological Chemistry 284:9, pages 5836-5844.
Crossref
Tohru Yamazaki, Junko Masuda, Tsutomu Omori, Ryosuke Usui, Hitomi Akiyama & Yoshiro Maru. (2009) EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility. Journal of Cell Science 122:2, pages 243-255.
Crossref
Nils Cordes, Stephanie Hehlgans & Iris Eke. 2009. The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies. The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies 93 115 .
P.S. Hodkinson & Tariq Sethi. 2009. Drug Resistance in Cancer Cells. Drug Resistance in Cancer Cells 115 135 .
Brian P. Chiswell, Rong Zhang, James W. Murphy, Titus J. Boggon & David A. Calderwood. (2008) The structural basis of integrin-linked kinase–PINCH interactions. Proceedings of the National Academy of Sciences 105:52, pages 20677-20682.
Crossref
Katherine L. TuckerTanya SageJoanne M. StevensPeter A. JordanSarah JonesNatasha E. BarrettRene St-ArnaudJonathan Frampton, Shoukat Dedhar & Jonathan M. Gibbins. (2008) A dual role for integrin-linked kinase in platelets: regulating integrin function and α-granule secretion. Blood 112:12, pages 4523-4531.
Crossref
Gerard W. Dougherty, Cynthia Jose, Mario Gimona & Mary Lou Cutler. (2008) The Rsu-1-PINCH1-ILK complex is regulated by Ras activation in tumor cells. European Journal of Cell Biology 87:8-9, pages 721-734.
Crossref
Xiaohua Shi, Hong Qu, Matthias Kretzler & Chuanyue Wu. (2008) Roles of PINCH-2 in regulation of glomerular cell shape change and fibronectin matrix deposition. American Journal of Physiology-Renal Physiology 295:1, pages F253-F263.
Crossref
Iveta Dobreva, Andrew Fielding, Leonard J. Foster & Shoukat Dedhar. (2008) Mapping the Integrin-Linked Kinase Interactome Using SILAC. Journal of Proteome Research 7:4, pages 1740-1749.
Crossref
Stephanie Hehlgans, Iris Eke, Yvonne Deuse & Nils Cordes. (2008) Integrin-linked kinase: Dispensable for radiation survival of three-dimensionally cultured fibroblasts. Radiotherapy and Oncology 86:3, pages 329-335.
Crossref
Jin-Ting Zhang, Da-Wei Wang, Qing-Xing Li, Zhen-Long Zhu, Ming-Wei Wang, Dong-Sheng Cui, Yan-Hong Yang, Yu-Xin Gu & Xiao-Feng Sun. (2007) Nuclear to cytoplasmic shift of p33ING1b protein from normal oral mucosa to oral squamous cell carcinoma in relation to clinicopathological variables. Journal of Cancer Research and Clinical Oncology 134:3, pages 421-426.
Crossref
Ka Chen, Yizeng Tu, Yongjun Zhang, Harry C. Blair, Lin Zhang & Chuanyue Wu. (2008) PINCH-1 Regulates the ERK-Bim Pathway and Contributes to Apoptosis Resistance in Cancer Cells. Journal of Biological Chemistry 283:5, pages 2508-2517.
Crossref
Robert Hall. (2007) H. P. S. Makkar, P. Siddhuraju, and K. Becker, Molecular Biotechnology: Plant Secondary Metabolites. Molecular Biotechnology 38:2, pages 185-185.
Crossref
Ingvild Birschmann, Silke Mietner, Marcus Dittrich, Julia Pfrang, Thomas Dandekar & Ulrich Walter. (2008) Use of functional highly purified human platelets for the identification of new proteins of the IPP signaling pathway. Thrombosis Research 122:1, pages 59-68.
Crossref
Alex Rossdeutsch, Nicola Smart & Paul R. Riley. (2007) Thymosin β4 and Ac-SDKP: Tools to mend a broken heart. Journal of Molecular Medicine 86:1, pages 29-35.
Crossref
Wenwu Zhang, Yidi Wu, Chuanyue Wu & Susan J. Gunst. (2007) Integrin-linked Kinase Regulates N-WASp-mediated Actin Polymerization and Tension Development in Tracheal Smooth Muscle. Journal of Biological Chemistry 282:47, pages 34568-34580.
Crossref
A. A. Terentiev & N. T. Moldogazieva. (2007) Cell adhesion proteins and α-fetoprotein. Similar structural motifs as prerequisites for common functions. Biochemistry (Moscow) 72:9, pages 920-935.
Crossref
Kenneth R. Norman, Shaun Cordes, Hiroshi Qadota, Poupak Rahmani & Donald G. Moerman. (2007) UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle. Developmental Biology 309:1, pages 45-55.
Crossref
Thitima Keskanokwong, Haley J. Shandro, Danielle E. Johnson, Saranya Kittanakom, Gonzalo L. Vilas, Paul Thorner, Reinhart A.F. Reithmeier, Varaporn Akkarapatumwong, Pa-thai Yenchitsomanus & Joseph R. Casey. (2007) Interaction of Integrin-linked Kinase with the Kidney Chloride/Bicarbonate Exchanger, kAE1. Journal of Biological Chemistry 282:32, pages 23205-23218.
Crossref
Wei Guo, Hui Jiang, Virginia Gray, Shoukat Dedhar & Yi Rao. (2007) Role of the integrin-linked kinase (ILK) in determining neuronal polarity. Developmental Biology 306:2, pages 457-468.
Crossref
Vasiliki Gkretsi, Wendy M. Mars, William C. Bowen, Lindsay Barua, Yu Yang, Lida Guo, René St.-Arnaud, Shoukat Dedhar, Chuanyue Wu & George K. Michalopoulos. (2007) Loss of integrin linked kinase from mouse hepatocytesin vitro andin vivo results in apoptosis and hepatitis. Hepatology 45:4, pages 1025-1034.
Crossref
Yun Liu, Jin Liu, Jie Chen, Libo Cheng, Qinhong Cao, Li Zhu, Yan Sun, Qinghuai Liu & Jianmin Li. (2007) Molecular cloning and characterization of a novel splice variant of the LIM domain family gene, PINCH 2, in human testis. Molecular Biotechnology 35:2, pages 109-118.
Crossref
Stephanie Hehlgans, Michael Haase & Nils Cordes. (2007) Signalling via integrins: Implications for cell survival and anticancer strategies. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1775:1, pages 163-180.
Crossref
Seung-Kyoon Kim, Hae-Ran Jang, Jeong-Hwan Kim, Seung-Moo Noh, Kyu-Sang Song, Mi-Rang Kim, Seun-Young Kim, Young-Il Yeom, Nam-Soon Kim, Hyang-Sook Yoo & Yong Sung Kim. (2006) The epigenetic silencing of LIMS2 in gastric cancer and its inhibitory effect on cell migration. Biochemical and Biophysical Research Communications 349:3, pages 1032-1040.
Crossref
Deepak Srivastava & Sangho Yu. (2006) Stretching to meet needs: integrin-linked kinase and the cardiac pump. Genes & Development 20:17, pages 2327-2331.
Crossref
Donald E. White, Pierre Coutu, Yan-Fen Shi, Jean-Claude Tardif, Stanley Nattel, René St. Arnaud, Shoukat Dedhar & William J. Muller. (2006) Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure. Genes & Development 20:17, pages 2355-2360.
Crossref
Mahnoush S. Shafiei & Don C. Rockey. (2006) The Role of Integrin-linked Kinase in Liver Wound Healing. Journal of Biological Chemistry 281:34, pages 24863-24872.
Crossref
Kazunori Mori, Masayuki Asakawa, Miki Hayashi, Miwako Imura, Takahiro Ohki, Etsuko Hirao, Joo-ri Kim-Kaneyama, Kiyoshi Nose & Motoko Shibanuma. (2006) Oligomerizing Potential of a Focal Adhesion LIM Protein Hic-5 Organizing a Nuclear-Cytoplasmic Shuttling Complex. Journal of Biological Chemistry 281:31, pages 22048-22061.
Crossref
Etienne Boulter, Dominique Grall, Sébastien Cagnol, Ellen Van Obberghen-Schilling, Etienne Boulter, Dominique Grall, Sébastien Cagnol & Ellen Van Obberghen-Schilling. (2006) Regulation of cell‐matrix adhesion dynamics and Rac‐1 by integrin linked kinase. The FASEB Journal 20:9, pages 1489-1491.
Crossref
Christina L Addison. (2006) Modulation of response to tumor therapies by the extracellular matrix. Future Oncology 2:3, pages 417-429.
Crossref
Georg Kontaxis, Klaus Bister & Robert Konrat. 2006. Handbook of Metalloproteins. Handbook of Metalloproteins.
Etienne Boulter & Ellen Van Obberghen-Schilling. (2006) Integrin-linked kinase and its partners: A modular platform regulating cell–matrix adhesion dynamics and cytoskeletal organization. European Journal of Cell Biology 85:3-4, pages 255-263.
Crossref
Yuan Chen, Meizan Lai, Yuka Maeno-Hikichi & Ji-fang Zhang. (2006) Essential role of the LIM domain in the formation of the PKCɛ–ENH–N-type Ca2+ channel complex. Cellular Signalling 18:2, pages 215-224.
Crossref
Zeng-Ren Zhao, Zhi-Yong Zhang, Dong-Sheng Cui, Li Jiang, Hui-Jun Zhang, Ming-Wei Wang & Xiao-Feng Sun. (2006) Particularly interesting new cysteine-histidine rich protein expression in colorectal adenocarcinomas. World Journal of Gastroenterology 12:2, pages 298.
Crossref
Kyle R. Legate, Eloi Montañez, Oliver Kudlacek & Reinhard Füssler. (2005) ILK, PINCH and parvin: the tIPP of integrin signalling. Nature Reviews Molecular Cell Biology 7:1, pages 20-31.
Crossref
J. L. Sepulveda & C. Wu. (2005) The parvins. Cellular and Molecular Life Sciences 63:1.
Crossref
Brad J. Martinsen, Ann N. Neumann, Allison J. Frasier, Clare V.H. Baker, Catherine E. Krull & Jamie L. Lohr. (2006) PINCH-1 expression during early avian embryogenesis: Implications for neural crest and heart development. Developmental Dynamics 235:1, pages 152-162.
Crossref
Alisa Vespa, Sudhir J.A. D'Souza & Lina Dagnino. (2005) A Novel Role for Integrin-linked Kinase in Epithelial Sheet Morphogenesis. Molecular Biology of the Cell 16:9, pages 4084-4095.
Crossref
Nolan R Filipenko, Sarah Attwell, Calvin Roskelley & Shoukat Dedhar. (2005) Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via α-PIX. Oncogene 24:38, pages 5837-5849.
Crossref
Janice L. Walker & Richard K. Assoian. (2005) Integrin-dependent signal transduction regulating cyclin D1 expression and G1 phase cell cycle progression. Cancer and Metastasis Reviews 24:3, pages 383-393.
Crossref
Maher N. Younes, Seungwon Kim, Orhan G. Yigitbasi, Mahitosh Mandal, Samar A. Jasser, Yasemin Dakak Yazici, Bradley A. Schiff, Adel El-Naggar, Benjamin N. Bekele, Gordon B. Mills & Jeffrey N. Myers. (2005) Integrin-linked kinase is a potential therapeutic target for anaplastic thyroid cancer. Molecular Cancer Therapeutics 4:8, pages 1146-1156.
Crossref
Boyi Gan, Zara K. Melkoumian, Xiaoyang Wu, Kun-Liang Guan & Jun-Lin Guan. (2005) Identification of FIP200 interaction with the TSC1–TSC2 complex and its role in regulation of cell size control. Journal of Cell Biology 170:3, pages 379-389.
Crossref
Daniel R Rhodes, Scott A Tomlins, Sooryanarayana Varambally, Vasudeva Mahavisno, Terrence Barrette, Shanker Kalyana-Sundaram, Debashis Ghosh, Akhilesh Pandey & Arul M Chinnaiyan. (2005) Probabilistic model of the human protein-protein interaction network. Nature Biotechnology 23:8, pages 951-959.
Crossref
Shaohua Li, Randi Bordoy, Fabio Stanchi, Markus Moser, Attila Braun, Oliver Kudlacek, Ulla M. Wewer, Peter D. Yurchenco & Reinhard Fässler. (2005) PINCH1 regulates cell-matrix and cell-cell adhesions, cell polarity and cell survival during the peri-implantation stage. Journal of Cell Science 118:13, pages 2913-2921.
Crossref
Simone Monika Blattner & Matthias Kretzler. (2005) Integrin-linked kinase in renal disease: connecting cell–matrix interaction to the cytoskeleton. Current Opinion in Nephrology & Hypertension 14:4, pages 404-410.
Crossref
Zhen Xu, Tomohiko Fukuda, You Li, Xiliang Zha, Jun Qin & Chuanyue Wu. (2005) Molecular Dissection of PINCH-1 Reveals a Mechanism of Coupling and Uncoupling of Cell Shape Modulation and Survival. Journal of Biological Chemistry 280:30, pages 27631-27637.
Crossref
Jaesun Chun, Sunghee Hyun, Taegun Kwon, Eun Jeoung Lee, Soon-Kwang Hong & Sang Sun Kang. (2005) The subcellular localization control of integrin linked kinase 1 through its protein–protein interaction with caveolin-1. Cellular Signalling 17:6, pages 751-760.
Crossref
Gerard W. Dougherty, Treasa Chopp, Sheng-mei Qi & Mary Lou Cutler. (2005) The Ras suppressor Rsu-1 binds to the LIM 5 domain of the adaptor protein PINCH1 and participates in adhesion-related functions. Experimental Cell Research 306:1, pages 168-179.
Crossref
Stephen J. Pratt, Holly Epple, Michael Ward, Yunfeng Feng, Vania M. Braga & Gregory D. Longmore. (2005) The LIM protein Ajuba influences p130Cas localization and Rac1 activity during cell migration. Journal of Cell Biology 168:5, pages 813-824.
Crossref
Gregory Hannigan, Armelle A. Troussard & Shoukat Dedhar. (2005) Integrin-linked kinase: a cancer therapeutic target unique among its ILK. Nature Reviews Cancer 5:1, pages 51-63.
Crossref
Jorge L. Sepulveda, Vasiliki Gkretsi & Chuanyue Wu. 2005. 183 225 .
Algirdas Velyvis & Jun Qin. 2005. Zinc Finger Proteins. Zinc Finger Proteins 99 105 .
Julie L. Kadrmas, Mark A. Smith, Kathleen A. Clark, Stephen M. Pronovost, Nemone Muster, John R. YatesIIIIII & Mary C. Beckerle. (2004) The integrin effector PINCH regulates JNK activity and epithelial migration in concert with Ras suppressor 1. Journal of Cell Biology 167:6, pages 1019-1024.
Crossref
Wara A.K.M. Khyrul, David P. LaLonde, Michael C. Brown, Howard Levinson & Christopher E. Turner. (2004) The Integrin-linked Kinase Regulates Cell Morphology and Motility in a Rho-associated Kinase-dependent Manner. Journal of Biological Chemistry 279:52, pages 54131-54139.
Crossref
Jingtang Gao, Gunnar Arbman, Ann Rearden & Xiao-Feng Sun. (2004) Stromal Staining for PINCH Is an Independent Prognostic Indicator in Colorectal Cancer. Neoplasia 6:6, pages 796-801.
Crossref
Julie L. Kadrmas & Mary C. Beckerle. (2004) The LIM domain: from the cytoskeleton to the nucleus. Nature Reviews Molecular Cell Biology 5:11, pages 920-931.
Crossref
Carsten Grashoff, Ingo Thievessen, Katrin Lorenz, Siegfried Ussar & Reinhard Fässler. (2004) Integrin-linked kinase: integrin’s mysterious partner. Current Opinion in Cell Biology 16:5, pages 565-571.
Crossref
Janet E Deane, Daniel P Ryan, Margaret Sunde, Megan J Maher, J Mitchell Guss, Jane E Visvader & Jacqueline M Matthews. (2004) Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex. The EMBO Journal 23:18, pages 3589-3598.
Crossref
Valérie Vouret-Craviari, Etienne Boulter, Dominique Grall, Cédric Matthews & Ellen Van Obberghen-Schilling. (2004) ILK is required for the assembly of matrix-forming adhesions and capillary morphogenesis in endothelial cells. Journal of Cell Science 117:19, pages 4559-4569.
Crossref
J.M. Stevens, P.A. Jordan, T. Sage & J.M. Gibbins. (2004) The regulation of integrin‐linked kinase in human platelets: evidence for involvement in the regulation of integrin α2β1. Journal of Thrombosis and Haemostasis 2:8, pages 1443-1452.
Crossref
Chuanyue Wu. (2004) The PINCH–ILK–parvin complexes: assembly, functions and regulation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1692:2-3, pages 55-62.
Crossref
Leila K. Mosavi, Tobin J. Cammett, Daniel C. Desrosiers & Zheng-yu Peng. (2004) The ankyrin repeat as molecular architecture for protein recognition. Protein Science 13:6, pages 1435-1448.
Crossref
Arusha Oloumi, Timothy McPhee & Shoukat Dedhar. (2004) Regulation of E-cadherin expression and β-catenin/Tcf transcriptional activity by the integrin-linked kinase. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1691:1, pages 1-15.
Crossref
Tomohiko Fukuda, Ka Chen, Xiaohua Shi & Chuanyue Wu. (2003) PINCH-1 Is an Obligate Partner of Integrin-linked Kinase (ILK) Functioning in Cell Shape Modulation, Motility, and Survival. Journal of Biological Chemistry 278:51, pages 51324-51333.
Crossref
Filippo G. GiancottiGuido Tarone. (2003) Positional Control of Cell Fate Through Joint Integrin/Receptor Protein Kinase Signaling. Annual Review of Cell and Developmental Biology 19:1, pages 173-206.
Crossref
Mathew G Miller, Izabela Naruszewicz, Ashu S Kumar, Toolsie Ramlal & Gregory E Hannigan. (2003) Integrin-linked kinase is a positive mediator of L6 myoblast differentiation. Biochemical and Biophysical Research Communications 310:3, pages 796-803.
Crossref
Ji Li, Hongwei Rao, Dean Burkin, Stephen J Kaufman & Chuanyue Wu. (2003) The muscle integrin binding protein (MIBP) interacts with α7β1 integrin and regulates cell adhesion and laminin matrix deposition. Developmental Biology 261:1, pages 209-219.
Crossref
Algirdas Velyvis, Julia Vaynberg, Yanwu Yang, Olga Vinogradova, Yongjun Zhang, Chuanyue Wu & Jun Qin. (2003) Structural and functional insights into PINCH LIM4 domain–mediated integrin signaling. Nature Structural & Molecular Biology 10:7, pages 558-564.
Crossref
Kathleen A. Clark, Maura McGrail & Mary C. Beckerle. (2003) Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes . Development 130:12, pages 2611-2621.
Crossref
Takao Sakai, Shaohua Li, Denitsa Docheva, Carsten Grashoff, Keiko Sakai, Günter Kostka, Attila Braun, Alexander Pfeifer, Peter D. Yurchenco & Reinhard Fässler. (2003) Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes & Development 17:7, pages 926-940.
Crossref
Carsten Grashoff, Attila Aszódi, Takao Sakai, Ernst B Hunziker & Reinhard Fässler. (2003) Integrin‐linked kinase regulates chondrocyte shape and proliferation. EMBO reports 4:4, pages 432-438.
Crossref
Yizeng Tu, Shan Wu, Xiaohua Shi, Ka Chen & Chuanyue Wu. (2003) Migfilin and Mig-2 Link Focal Adhesions to Filamin and the Actin Cytoskeleton and Function in Cell Shape Modulation. Cell 113:1, pages 37-47.
Crossref
Attila Braun, Randi Bordoy, Fabio Stanchi, Markus Moser, G.ünter Kostka, Elisabeth Ehler, Oliver Brandau & Reinhard Fässler. (2003) PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions☆. Experimental Cell Research 284:2, pages 237-248.
Crossref
Julia Mills, Murat Digicaylioglu, Arthur T. Legg, Clint E. Young, Sean S. Young, Alasdair M. Barr, Lauren Fletcher, Timothy P. O'Connor & Shoukat Dedhar. (2003) Role of Integrin-Linked Kinase in Nerve Growth Factor-Stimulated Neurite Outgrowth. The Journal of Neuroscience 23:5, pages 1638-1648.
Crossref
Yongjun Zhang, Ka Chen, Yizeng Tu, Algirdas Velyvis, Yanwu Yang, Jun Qin & Chuanyue Wu. (2002) Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites. Journal of Cell Science 115:24, pages 4777-4786.
Crossref
Yongjun Zhang, Ka Chen, Lida Guo & Chuanyue Wu. (2002) Characterization of PINCH-2, a New Focal Adhesion Protein That Regulates the PINCH-1-ILK Interaction, Cell Spreading, and Migration. Journal of Biological Chemistry 277:41, pages 38328-38338.
Crossref
Patricia McLoughlin, Elisabeth Ehler, Graeme Carlile, Jonathan D. Licht & Beat W. Schäfer. (2002) The LIM-only Protein DRAL/FHL2 Interacts with and Is a Corepressor for the Promyelocytic Leukemia Zinc Finger Protein. Journal of Biological Chemistry 277:40, pages 37045-37053.
Crossref
Jessica Wang-Rodriguez, Anna D. Dreilinger, Ghazwan M. Alsharabi & Ann Rearden. (2002) The signaling adapter protein PINCH is up-regulated in the stroma of common cancers, notably at invasive edges. Cancer 95:6, pages 1387-1395.
Crossref
László Buday, Livius Wunderlich & Peter Tamás. (2002) The Nck family of adapter proteins. Cellular Signalling 14:9, pages 723-731.
Crossref
Lida Guo & Chuanyue Wu. (2002) Regulation of fibronectin matrix deposition and cell proliferation by the PINCH‐ILK‐CH‐ILKBP complex. The FASEB Journal 16:10, pages 1298-1300.
Crossref
A.Craig Mackinnon, Hiroshi Qadota, Kenneth R. Norman, Donald G. Moerman & Benjamin D. Williams. (2002) C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin Adhesion Complexes. Current Biology 12:10, pages 787-797.
Crossref
R. L. Juliano. (2002) Signal Transduction by Cell Adhesion Receptors and the Cytoskeleton: Functions of Integrins, Cadherins, Selectins, and Immunoglobulin-Superfamily Members. Annual Review of Pharmacology and Toxicology 42:1, pages 283-323.
Crossref
N. Yoganathan, A. Yee, Z. Zhang, D. Leung, J. Yan, L. Fazli, D.L. Kojic, P.C. Costello, M. Jabali, S. Dedhar & J. Sanghera. (2002) Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties. Pharmacology & Therapeutics 93:2-3, pages 233-242.
Crossref
Sotiris N. Nikolopoulos & Christopher E. Turner. (2002) Molecular Dissection of Actopaxin-Integrin-linked Kinase-Paxillin Interactions and Their Role in Subcellular Localization. Journal of Biological Chemistry 277:2, pages 1568-1575.
Crossref
Yongjun Zhang, Lida Guo, Ka Chen & Chuanyue Wu. (2002) A Critical Role of the PINCH-Integrin-linked Kinase Interaction in the Regulation of Cell Shape Change and Migration. Journal of Biological Chemistry 277:1, pages 318-326.
Crossref

Displaying 200 of 234 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.