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Bridging the Gap: Composition, Regulation, and Physiological Function of the IκB Kinase Complex

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Pages 4547-4551 | Published online: 28 Mar 2023

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Xiaolei Hu, Hengyan Zhang, Langen Zhuang, Guoxi Jin, Qingqing Yang, Min Li, Weihua Sun & Fengling Chen. (2020) Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-κB p65 Nuclear Translocation and the Ubiquitination and Degradation of IκBα. Drug Design, Development and Therapy 14, pages 795-810.
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Sebastian Tegethoff, Joachim Behlke & Claus Scheidereit. (2003) Tetrameric Oligomerization of IκB Kinase γ (IKKγ) Is Obligatory for IKK Complex Activity and NF-κB Activation. Molecular and Cellular Biology 23:6, pages 2029-2041.
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Yolanda Bayon, Maria A. Ortiz, Francisco J. Lopez-Hernandez, Feng Gao, Michael Karin, Magnus Pfahl & F. Javier Piedrafita. (2003) Inhibition of IκB Kinase by a New Class of Retinoid-Related Anticancer Agents That Induce Apoptosis. Molecular and Cellular Biology 23:3, pages 1061-1074.
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Ray-Chang Wu, Jun Qin, Yoshihiro Hashimoto, Jiemin Wong, Jianming Xu, Sophia Y. Tsai, Ming-Jer Tsai & Bert W. O'Malley. (2002) Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase. Molecular and Cellular Biology 22:10, pages 3549-3561.
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Kam C. Yeung, David W. Rose, Amardeep S. Dhillon, Diane Yaros, Marcus Gustafsson, Devasis Chatterjee, Brian McFerran, James Wyche, Walter Kolch & John M. Sedivy. (2001) Raf Kinase Inhibitor Protein Interacts with NF-κB-Inducing Kinase and TAK1 and Inhibits NF-κB Activation. Molecular and Cellular Biology 21:21, pages 7207-7217.
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Anne Devin, Yong Lin, Shoji Yamaoka, Zhiwei Li, Michael Karin & Zheng-gang Liu. (2001) The α and β Subunits of IκB Kinase (IKK) Mediate TRAF2-Dependent IKK Recruitment to Tumor Necrosis Factor (TNF) Receptor 1 in Response to TNF. Molecular and Cellular Biology 21:12, pages 3986-3994.
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Manabu Furukawa, Yanping Zhang, Joseph McCarville, Tomohiko Ohta & Yue Xiong. (2000) The CUL1 C-Terminal Sequence and ROC1 Are Required for Efficient Nuclear Accumulation, NEDD8 Modification, and Ubiquitin Ligase Activity of CUL1. Molecular and Cellular Biology 20:21, pages 8185-8197.
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Antonio Castrillo, María J. M. Díaz-Guerra, Sonsoles Hortelano, Paloma Martín-Sanz & Lisardo Boscá. (2000) Inhibition of IκB Kinase and IκB Phosphorylation by 15-Deoxy-Δ12,14-Prostaglandin J2 in Activated Murine Macrophages. Molecular and Cellular Biology 20:5, pages 1692-1698.
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Lee V. Madrid, Cun-Yu Wang, Denis C. Guttridge, Arndt J. G. Schottelius, Albert S. Baldwin$suffix/text()$suffix/text() & Marty W. Mayo. (2000) Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB. Molecular and Cellular Biology 20:5, pages 1626-1638.
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Alison O'Mahony, Xin Lin, Romas Geleziunas & Warner C. Greene. (2000) Activation of the Heterodimeric IκB Kinase α (IKKα)-IKKβ Complex Is Directional: IKKα Regulates IKKβ under Both Basal and Stimulated Conditions. Molecular and Cellular Biology 20:4, pages 1170-1178.
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