Molecular and Cellular Biology, Volume 19, Issue 7 (1999)

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Molecular and Cellular Biology, Volume 19, Issue 7 (1999)

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Minireviews

Article
Bridging the Gap: Composition, Regulation, and Physiological Function of the IκB Kinase Complex
Ebrahim Zandi & Michael Karin
Pages: 4547-4551
Published online: 28 Mar 2023
First Page PreviewforBridging the Gap: Composition, Regulation, and Physiological Function of the IκB Kinase Complex | Full Text | References | PDF (159.9 KB)
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Gene Expression

Article
An mRNA Stability Complex Functions with Poly(A)-Binding Protein To Stabilize mRNA In Vitro
Zuoren Wang, Nancy Day, Panayiota Trifillis & Megerditch Kiledjian
Pages: 4552-4560
Published online: 28 Mar 2023
AbstractforAn mRNA Stability Complex Functions with Poly(A)-Binding Protein To Stabilize mRNA In Vitro | Full Text | References | PDF (1,012.4 KB)
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Article
Std1 and Mth1 Proteins Interact with the Glucose Sensors To Control Glucose-Regulated Gene Expression in Saccharomyces cerevisiae
Martin C. Schmidt, Rhonda R. McCartney, Xudong Zhang, Tommy S. Tillman, Harry Solimeo, Stefan Wölfl, Ciprian Almonte & Simon C. Watkins
Pages: 4561-4571
Published online: 28 Mar 2023
AbstractforStd1 and Mth1 Proteins Interact with the Glucose Sensors To Control Glucose-Regulated Gene Expression in Saccharomyces cerevisiae | Full Text | References | PDF (3.4 MB)
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Article
Assembly of the α-Globin mRNA Stability Complex Reflects Binary Interaction between the Pyrimidine-Rich 3′ Untranslated Region Determinant and Poly(C) Binding Protein αCP
Alexander N. Chkheidze, Dmitry L. Lyakhov, Alexander V. Makeyev, Julia Morales, Jian Kong & Stephen A. Liebhaber
Pages: 4572-4581
Published online: 28 Mar 2023
AbstractforAssembly of the α-Globin mRNA Stability Complex Reflects Binary Interaction between the Pyrimidine-Rich 3′ Untranslated Region Determinant and Poly(C) Binding Protein αCP | Full Text | References | PDF (1.7 MB)
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Article
Dominant Negative Murine Serum Response Factor: Alternative Splicing within the Activation Domain Inhibits Transactivation of Serum Response Factor Binding Targets
Narasimhaswamy S. Belaguli, Wei Zhou, Thuy-Hanh T. Trinh, Mark W. Majesky & Robert J. Schwartz
Pages: 4582-4591
Published online: 28 Mar 2023
AbstractforDominant Negative Murine Serum Response Factor: Alternative Splicing within the Activation Domain Inhibits Transactivation of Serum Response Factor Binding Targets | Full Text | References | PDF (1,015.3 KB)
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Article
Major Egr3 Isoforms Are Generated via Alternate Translation Start Sites and Differ in Their Abilities To Activate Transcription
Kevin J. O’Donovan & Jay M. Baraban
Pages: 4711-4718
Published online: 28 Mar 2023
AbstractforMajor Egr3 Isoforms Are Generated via Alternate Translation Start Sites and Differ in Their Abilities To Activate Transcription | Full Text | References | PDF (1,020.9 KB)
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Article
Activation of a Delayed-Early Gene Encoding MHR3 by the Ecdysone Receptor Heterodimer EcR-B1–USP-1 but Not by EcR-B1–USP-2
Que Lan, Kiyoshi Hiruma, Xiao Hu, Marek Jindra & Lynn M. Riddiford
Pages: 4897-4906
Published online: 28 Mar 2023
AbstractforActivation of a Delayed-Early Gene Encoding MHR3 by the Ecdysone Receptor Heterodimer EcR-B1–USP-1 but Not by EcR-B1–USP-2 | Full Text | References | PDF (840.9 KB)
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Article
Enhancer-Dependent Transcriptional Oscillations in Mouse Erythroleukemia Cells
Yong-Qing Feng, Raouf Alami & Eric E. Bouhassira
Pages: 4907-4917
Published online: 28 Mar 2023
AbstractforEnhancer-Dependent Transcriptional Oscillations in Mouse Erythroleukemia Cells | Full Text | References | PDF (917.2 KB)
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Article
Activation of RNA Polymerase III Transcription in Cells Transformed by Simian Virus 40
Christopher G. C. Larminie, Josephine E. Sutcliffe, Kerrie Tosh, Andrew G. Winter, Zoe A. Felton-Edkins & Robert J. White
Pages: 4927-4934
Published online: 28 Mar 2023
AbstractforActivation of RNA Polymerase III Transcription in Cells Transformed by Simian Virus 40 | Full Text | References | PDF (2.8 MB)
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Article
Utilization of Splicing Elements and Polyadenylation Signal Elements in the Coupling of Polyadenylation and Last-Intron Removal
Charles Cooke, Holly Hans & James C. Alwine
Pages: 4971-4979
Published online: 28 Mar 2023
AbstractforUtilization of Splicing Elements and Polyadenylation Signal Elements in the Coupling of Polyadenylation and Last-Intron Removal | Full Text | References | PDF (272.3 KB)
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Article
Trimeric Association of Hox and TALE Homeodomain Proteins Mediates Hoxb2 Hindbrain Enhancer Activity
Yakop Jacobs, Catherine A. Schnabel & Michael L. Cleary
Pages: 5134-5142
Published online: 28 Mar 2023
AbstractforTrimeric Association of Hox and TALE Homeodomain Proteins Mediates Hoxb2 Hindbrain Enhancer Activity | Full Text | References | PDF (1.8 MB)
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Transcriptional Regulation

Article
Highly Divergent Lentiviral Tat Proteins Activate Viral Gene Expression by a Common Mechanism
Paul D. Bieniasz, Therese A. Grdina, Hal P. Bogerd & Bryan R. Cullen
Pages: 4592-4599
Published online: 28 Mar 2023
AbstractforHighly Divergent Lentiviral Tat Proteins Activate Viral Gene Expression by a Common Mechanism | Full Text | References | PDF (833.5 KB)
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Article
Target Specificities of Drosophila Enhancer of split Basic Helix-Loop-Helix Proteins
Barbara H. Jennings, David M. Tyler & Sarah J. Bray
Pages: 4600-4610
Published online: 28 Mar 2023
AbstractforTarget Specificities of Drosophila Enhancer of split Basic Helix-Loop-Helix Proteins | Full Text | References | PDF (2.2 MB)
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Article
Transcriptional Cofactor CA150 Regulates RNA Polymerase II Elongation in a TATA-Box-Dependent Manner
Carlos Suñé & Mariano A. Garcia-Blanco
Pages: 4719-4728
Published online: 28 Mar 2023
AbstractforTranscriptional Cofactor CA150 Regulates RNA Polymerase II Elongation in a TATA-Box-Dependent Manner | Full Text | References | PDF (1.2 MB)
  • 8 Views
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Article
p70s6k Integrates Phosphatidylinositol 3-Kinase and Rapamycin-Regulated Signals for E2F Regulation in T Lymphocytes
Paul Brennan, J. W. Babbage, G. Thomas & Doreen Cantrell
Pages: 4729-4738
Published online: 28 Mar 2023
Abstractforp70s6k Integrates Phosphatidylinositol 3-Kinase and Rapamycin-Regulated Signals for E2F Regulation in T Lymphocytes | Full Text | References | PDF (1.3 MB)
  • 30 Views
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Article
Upstream Stimulatory Factor Regulates Major Histocompatibility Complex Class I Gene Expression: the U2ΔE4 Splice Variant Abrogates E-Box Activity
T. Kevin Howcroft, Charles Murphy, Jocelyn D. Weissman, Sam J. Huber, Michèle Sawadogo & Dinah S. Singer
Pages: 4788-4797
Published online: 28 Mar 2023
AbstractforUpstream Stimulatory Factor Regulates Major Histocompatibility Complex Class I Gene Expression: the U2ΔE4 Splice Variant Abrogates E-Box Activity | Full Text | References | PDF (544.2 KB)
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Article
Activation of Phosphatidylinositol 3-Kinase in Response to Interleukin-1 Leads to Phosphorylation and Activation of the NF-κB p65/RelA Subunit
Nywana Sizemore, Stewart Leung & George R. Stark
Pages: 4798-4805
Published online: 28 Mar 2023
AbstractforActivation of Phosphatidylinositol 3-Kinase in Response to Interleukin-1 Leads to Phosphorylation and Activation of the NF-κB p65/RelA Subunit | Full Text | References | PDF (1.9 MB)
  • 52 Views
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Article
Repressive Effect of Sp1 on the C/EBPα Gene Promoter: Role in Adipocyte Differentiation
Qi-Qun Tang, Man-Shiow Jiang & M. Daniel Lane
Pages: 4855-4865
Published online: 28 Mar 2023
AbstractforRepressive Effect of Sp1 on the C/EBPα Gene Promoter: Role in Adipocyte Differentiation | Full Text | References | PDF (6.1 MB)
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Article
Homeoproteins CDP and SATB1 Interact: Potential for Tissue-Specific Regulation
Jinqi Liu, Anna Barnett, Ellis J. Neufeld & Jaquelin P. Dudley
Pages: 4918-4926
Published online: 28 Mar 2023
AbstractforHomeoproteins CDP and SATB1 Interact: Potential for Tissue-Specific Regulation | Full Text | References | PDF (1.7 MB)
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Article
The Naturally Occurring Mutants of DDB Are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription
Pavel Shiyanov, Steven A. Hayes, Manjula Donepudi, Anne F. Nichols, Stuart Linn, Betty L. Slagle & Pradip Raychaudhuri
Pages: 4935-4943
Published online: 28 Mar 2023
AbstractforThe Naturally Occurring Mutants of DDB Are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription | Full Text | References | PDF (1.2 MB)
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Article
Cloning and Characterization of Two Evolutionarily Conserved Subunits (TFIIIC102 and TFIIIC63) of Human TFIIIC and Their Involvement in Functional Interactions with TFIIIB and RNA Polymerase III
Yng-Ju Hsieh, Zhengxin Wang, Robert Kovelman & Robert G. Roeder
Pages: 4944-4952
Published online: 28 Mar 2023
AbstractforCloning and Characterization of Two Evolutionarily Conserved Subunits (TFIIIC102 and TFIIIC63) of Human TFIIIC and Their Involvement in Functional Interactions with TFIIIB and RNA Polymerase III | Full Text | References | PDF (1.4 MB)
  • 29 Views
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Article
Synergistic Transcriptional Activation by TATA-Binding Protein and hTAFII28 Requires Specific Amino Acids of the hTAFII28 Histone Fold
Anne-Claire Lavigne, Yann-Gaël Gangloff, Lucie Carré, Gabrielle Mengus, Catherine Birck, Olivier Poch, Christophe Romier, Dino Moras & Irwin Davidson
Pages: 5050-5060
Published online: 28 Mar 2023
AbstractforSynergistic Transcriptional Activation by TATA-Binding Protein and hTAFII28 Requires Specific Amino Acids of the hTAFII28 Histone Fold | Full Text | References | PDF (1.3 MB)
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Article
The Linker Domain of Stat1 Is Required for Gamma Interferon-Driven Transcription
Edward Yang, Zilong Wen, Richard L. Haspel, Jue J. Zhang & James E. Darnell Jr.
Pages: 5106-5112
Published online: 28 Mar 2023
AbstractforThe Linker Domain of Stat1 Is Required for Gamma Interferon-Driven Transcription | Full Text | References | PDF (1.5 MB)
  • 21 Views
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Article
Trithorax- and Polycomb-Group Response Elements within an Ultrabithorax Transcription Maintenance Unit Consist of Closely Situated but Separable Sequences
Sergei Tillib, Svetlana Petruk, Yurii Sedkov, Alexander Kuzin, Miki Fujioka, Tadaatsu Goto & Alexander Mazo
Pages: 5189-5202
Published online: 28 Mar 2023
AbstractforTrithorax- and Polycomb-Group Response Elements within an Ultrabithorax Transcription Maintenance Unit Consist of Closely Situated but Separable Sequences | Full Text | References | PDF (2.6 MB)
  • 22 Views
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Article
Spatial Organization of the Core Region of Yeast TFIIIB-DNA Complexes
Jim Persinger, Sarojini M. Sengupta & Blaine Bartholomew
Pages: 5218-5234
Published online: 28 Mar 2023
AbstractforSpatial Organization of the Core Region of Yeast TFIIIB-DNA Complexes | Full Text | References | PDF (7.6 MB)
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Cell Growth and Development

Article
Ras-Specific Exchange Factor GRF: Oligomerization through Its Dbl Homology Domain and Calcium-Dependent Activation of Raf
Pieter H. Anborgh, Xiaolan Qian, Alex G. Papageorge, William C. Vass, Jeffrey E. DeClue & Douglas R. Lowy
Pages: 4611-4622
Published online: 28 Mar 2023
AbstractforRas-Specific Exchange Factor GRF: Oligomerization through Its Dbl Homology Domain and Calcium-Dependent Activation of Raf | Full Text | References | PDF (1.3 MB)
  • 38 Views
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Article
Cellular Ras and Cyclin D1 Are Required during Different Cell Cycle Periods in Cycling NIH 3T3 Cells
Masahiro Hitomi & Dennis W. Stacey
Pages: 4623-4632
Published online: 28 Mar 2023
AbstractforCellular Ras and Cyclin D1 Are Required during Different Cell Cycle Periods in Cycling NIH 3T3 Cells | Full Text | References | PDF (285.9 KB)
  • 26 Views
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Article
Interaction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals
Nicola J. Marston, William J. Richards, David Hughes, David Bertwistle, Christopher J. Marshall & Alan Ashworth
Pages: 4633-4642
Published online: 28 Mar 2023
AbstractforInteraction between the Product of the Breast Cancer Susceptibility Gene BRCA2 and DSS1, a Protein Functionally Conserved from Yeast to Mammals | Full Text | References | PDF (3.4 MB)
  • 39 Views
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Article
Mutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase
Xiaoxia Li, Mairead Commane, Carmel Burns, Kalpa Vithalani, Zhaodan Cao & George R. Stark
Pages: 4643-4652
Published online: 28 Mar 2023
AbstractforMutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase | Full Text | References | PDF (1.2 MB)
  • 36 Views
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Article
Induction of Apoptosis by Double-Stranded-RNA-Dependent Protein Kinase (PKR) Involves the α Subunit of Eukaryotic Translation Initiation Factor 2 and NF-κB
Jesús Gil, José Alcamí & Mariano Esteban
Pages: 4653-4663
Published online: 28 Mar 2023
AbstractforInduction of Apoptosis by Double-Stranded-RNA-Dependent Protein Kinase (PKR) Involves the α Subunit of Eukaryotic Translation Initiation Factor 2 and NF-κB | Full Text | References | PDF (1,022 KB)
  • 33 Views
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Article
c-Myc Regulates Cyclin D-Cdk4 and -Cdk6 Activity but Affects Cell Cycle Progression at Multiple Independent Points
Maria K. Mateyak, Alvaro J. Obaya & John M. Sedivy
Pages: 4672-4683
Published online: 28 Mar 2023
Abstractforc-Myc Regulates Cyclin D-Cdk4 and -Cdk6 Activity but Affects Cell Cycle Progression at Multiple Independent Points | Full Text | References | PDF (1.8 MB)
  • 87 Views
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Article
Osmotic Shock Inhibits Insulin Signaling by Maintaining Akt/Protein Kinase B in an Inactive Dephosphorylated State
Dong Chen, Raymond V. Fucini, Ann Louise Olson, Brian A. Hemmings & Jeffrey E. Pessin
Pages: 4684-4694
Published online: 28 Mar 2023
AbstractforOsmotic Shock Inhibits Insulin Signaling by Maintaining Akt/Protein Kinase B in an Inactive Dephosphorylated State | Full Text | References | PDF (1.5 MB)
  • 29 Views
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Article
Serum-Induced Expression of the cdc25A Gene by Relief of E2F-Mediated Repression
Xi Chen & Ron Prywes
Pages: 4695-4702
Published online: 28 Mar 2023
AbstractforSerum-Induced Expression of the cdc25A Gene by Relief of E2F-Mediated Repression | Full Text | References | PDF (303.6 KB)
  • 13 Views
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Article
Suppression of E1A-Mediated Transformation by the p50E4F Transcription Factor
Elma R. Fernandes & Robert J. Rooney
Pages: 4739-4749
Published online: 28 Mar 2023
AbstractforSuppression of E1A-Mediated Transformation by the p50E4F Transcription Factor | Full Text | References | PDF (705.8 KB)
  • 2 Views
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Article
SDF-2 Induction of Terminal Differentiation in Dictyostelium discoideum Is Mediated by the Membrane-Spanning Sensor Kinase DhkA
Nancy Wang, Fredrik Söderbom, Christophe Anjard, Gad Shaulsky & William F. Loomis
Pages: 4750-4756
Published online: 28 Mar 2023
AbstractforSDF-2 Induction of Terminal Differentiation in Dictyostelium discoideum Is Mediated by the Membrane-Spanning Sensor Kinase DhkA | Full Text | References | PDF (235.9 KB)
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Article
Inhibition of Double-Stranded RNA- and Tumor Necrosis Factor Alpha-Mediated Apoptosis by Tetratricopeptide Repeat Protein and Cochaperone P58IPK
Norina M. Tang, Marcus J. Korth, Michael Gale Jr., Marlene Wambach, Sandy D. Der, Sudip K. Bandyopadhyay, Bryan R. G. Williams & Michael G. Katze
Pages: 4757-4765
Published online: 28 Mar 2023
AbstractforInhibition of Double-Stranded RNA- and Tumor Necrosis Factor Alpha-Mediated Apoptosis by Tetratricopeptide Repeat Protein and Cochaperone P58IPK | Full Text | References | PDF (4.2 MB)
  • 5 Views
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Article
Activating Phosphorylation of the Kin28p Subunit of Yeast TFIIH by Cak1p
Jonathan Kimmelman, Philipp Kaldis, Christoph J. Hengartner, Geoffrey M. Laff, Sang Seok Koh, Richard A. Young & Mark J. Solomon
Pages: 4774-4787
Published online: 28 Mar 2023
AbstractforActivating Phosphorylation of the Kin28p Subunit of Yeast TFIIH by Cak1p | Full Text | References | PDF (1.8 MB)
  • 12 Views
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Article
Induced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2
James D. Owen, Paul J. Ruest, David W. Fry & Steven K. Hanks
Pages: 4806-4818
Published online: 28 Mar 2023
AbstractforInduced Focal Adhesion Kinase (FAK) Expression in FAK-Null Cells Enhances Cell Spreading and Migration Requiring Both Auto- and Activation Loop Phosphorylation Sites and Inhibits Adhesion-Dependent Tyrosine Phosphorylation of Pyk2 | Full Text | References | PDF (5.8 MB)
  • 84 Views
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Article
Tyrosine Phosphorylation of the Proto-Oncoprotein Raf-1 Is Regulated by Raf-1 Itself and the Phosphatase Cdc25A
Kai Xia, Robert S. Lee, Radha P. Narsimhan, Nishit K. Mukhopadhyay, Benjamin G. Neel & Thomas M. Roberts
Pages: 4819-4824
Published online: 28 Mar 2023
AbstractforTyrosine Phosphorylation of the Proto-Oncoprotein Raf-1 Is Regulated by Raf-1 Itself and the Phosphatase Cdc25A | Full Text | References | PDF (1.3 MB)
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Article
p53 Mediates Apoptotic Crisis in Primary Abelson Virus-Transformed Pre-B Cells
Indira Unnikrishnan, Arash Radfar, Jenia Jenab-Wolcott & Naomi Rosenberg
Pages: 4825-4831
Published online: 28 Mar 2023
Abstractforp53 Mediates Apoptotic Crisis in Primary Abelson Virus-Transformed Pre-B Cells | Full Text | References | PDF (1.7 MB)
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Article
BRCA1 Is Phosphorylated at Serine 1497 In Vivo at a Cyclin-Dependent Kinase 2 Phosphorylation Site
Heinz Ruffner, Wei Jiang, A. Grey Craig, Tony Hunter & Inder M. Verma
Pages: 4843-4854
Published online: 28 Mar 2023
AbstractforBRCA1 Is Phosphorylated at Serine 1497 In Vivo at a Cyclin-Dependent Kinase 2 Phosphorylation Site | Full Text | References | PDF (3.1 MB)
  • 22 Views
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Article
Fanconi Anemia Proteins FANCA, FANCC, and FANCG/XRCC9 Interact in a Functional Nuclear Complex
Irene Garcia-Higuera, Yanan Kuang, Dieter Näf, Jennifer Wasik & Alan D. D’Andrea
Pages: 4866-4873
Published online: 28 Mar 2023
AbstractforFanconi Anemia Proteins FANCA, FANCC, and FANCG/XRCC9 Interact in a Functional Nuclear Complex | Full Text | References | PDF (2.8 MB)
  • 56 Views
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Article
Cyclic AMP-Dependent Protein Kinase Regulates Pseudohyphal Differentiation in Saccharomyces cerevisiae
Xuewen Pan & Joseph Heitman
Pages: 4874-4887
Published online: 28 Mar 2023
AbstractforCyclic AMP-Dependent Protein Kinase Regulates Pseudohyphal Differentiation in Saccharomyces cerevisiae | Full Text | References | PDF (5.6 MB)
  • 67 Views
  • 290 CrossRef citations
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Article
Cell Cycle Control of Cdc7p Kinase Activity through Regulation of Dbf4p Stability
Guy Oshiro, Julia C. Owens, Yiqun Shellman, Robert A. Sclafani & Joachim J. Li
Pages: 4888-4896
Published online: 28 Mar 2023
AbstractforCell Cycle Control of Cdc7p Kinase Activity through Regulation of Dbf4p Stability | Full Text | References | PDF (3 MB)
  • 18 Views
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Article
Physiological Requirement for Both SH2 Domains for Phospholipase C-γ1 Function and Interaction with Platelet-Derived Growth Factor Receptors
Qun-sheng Ji, Ansuman Chattopadhyay, Manuela Vecchi & Graham Carpenter
Pages: 4961-4970
Published online: 28 Mar 2023
AbstractforPhysiological Requirement for Both SH2 Domains for Phospholipase C-γ1 Function and Interaction with Platelet-Derived Growth Factor Receptors | Full Text | References | PDF (1.4 MB)
  • 15 Views
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Article
SOCS-3 Is Tyrosine Phosphorylated in Response to Interleukin-2 and Suppresses STAT5 Phosphorylation and Lymphocyte Proliferation
Solomon J. Cohney, David Sanden, Nicholas A. Cacalano, Akihiko Yoshimura, Alice Mui, Thi Sau Migone & James A. Johnston
Pages: 4980-4988
Published online: 28 Mar 2023
AbstractforSOCS-3 Is Tyrosine Phosphorylated in Response to Interleukin-2 and Suppresses STAT5 Phosphorylation and Lymphocyte Proliferation | Full Text | References | PDF (1.4 MB)
  • 13 Views
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Article
Mechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase
Nathalie Filippa, Carol L. Sable, Chantal Filloux, Brian Hemmings & Emmanuel Van Obberghen
Pages: 4989-5000
Published online: 28 Mar 2023
AbstractforMechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase | Full Text | References | PDF (2.3 MB)
  • 24 Views
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Article
Human Cdc34 and Rad6B Ubiquitin-Conjugating Enzymes Target Repressors of Cyclic AMP-Induced Transcription for Proteolysis
Debananda Pati, Marvin L. Meistrich & Sharon E. Plon
Pages: 5001-5013
Published online: 28 Mar 2023
AbstractforHuman Cdc34 and Rad6B Ubiquitin-Conjugating Enzymes Target Repressors of Cyclic AMP-Induced Transcription for Proteolysis | Full Text | References | PDF (1.8 MB)
  • 42 Views
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Article
Regulation of Nuclear Localization and Transcriptional Activity of TFII-I by Bruton’s Tyrosine Kinase
Carl D. Novina, Sanjay Kumar, Urmila Bajpai, Venugopalan Cheriyath, Keming Zhang, Shiv Pillai, Henry H. Wortis & Ananda L. Roy
Pages: 5014-5024
Published online: 28 Mar 2023
AbstractforRegulation of Nuclear Localization and Transcriptional Activity of TFII-I by Bruton’s Tyrosine Kinase | Full Text | References | PDF (1.6 MB)
  • 14 Views
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Article
Disordered T-Cell Development and T-Cell Malignancies in SCL LMO1 Double-Transgenic Mice: Parallels with E2A-Deficient Mice
David S. Chervinsky, Xian-Feng Zhao, Du H. Lam, MaryKay Ellsworth, Kenneth W. Gross & Peter D. Aplan
Pages: 5025-5035
Published online: 28 Mar 2023
AbstractforDisordered T-Cell Development and T-Cell Malignancies in SCL LMO1 Double-Transgenic Mice: Parallels with E2A-Deficient Mice | Full Text | References | PDF (3.2 MB)
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Article
Distinct Glucocorticoid Receptor Transcriptional Regulatory Surfaces Mediate the Cytotoxic and Cytostatic Effects of Glucocorticoids
Inez Rogatsky, Adam B. Hittelman, David Pearce & Michael J. Garabedian
Pages: 5036-5049
Published online: 28 Mar 2023
AbstractforDistinct Glucocorticoid Receptor Transcriptional Regulatory Surfaces Mediate the Cytotoxic and Cytostatic Effects of Glucocorticoids | Full Text | References | PDF (3.1 MB)
  • 11 Views
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Article
Domain Swapping Used To Investigate the Mechanism of Protein Kinase B Regulation by 3-Phosphoinositide-Dependent Protein Kinase 1 and Ser473 Kinase
Mirjana Andjelković, Sauveur-Michel Maira, Peter Cron, Peter J. Parker & Brian A. Hemmings
Pages: 5061-5072
Published online: 28 Mar 2023
AbstractforDomain Swapping Used To Investigate the Mechanism of Protein Kinase B Regulation by 3-Phosphoinositide-Dependent Protein Kinase 1 and Ser473 Kinase | Full Text | References | PDF (1.6 MB)
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Article
Cell Cycle Withdrawal Promotes Myogenic Induction of Akt, a Positive Modulator of Myocyte Survival
Yasushi Fujio, Kun Guo, Toshiaki Mano, Yasuhiro Mitsuuchi, Joseph R. Testa & Kenneth Walsh
Pages: 5073-5082
Published online: 28 Mar 2023
AbstractforCell Cycle Withdrawal Promotes Myogenic Induction of Akt, a Positive Modulator of Myocyte Survival | Full Text | References | PDF (1.8 MB)
  • 11 Views
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Article
A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells
Hiroyuki Kumagai, Noriko Sato, Masayuki Yamada, Daniel Mahony, Wolfgang Seghezzi, Emma Lees, Ken-Ichi Arai & Hisao Masai
Pages: 5083-5095
Published online: 28 Mar 2023
AbstractforA Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells | Full Text | References | PDF (2.8 MB)
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Overproduction of Human Myt1 Kinase Induces a G2 Cell Cycle Delay by Interfering with the Intracellular Trafficking of Cdc2-Cyclin B1 Complexes
Feng Liu, Cynthia Rothblum-Oviatt, Christine E. Ryan & Helen Piwnica-Worms
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Published online: 28 Mar 2023
AbstractforOverproduction of Human Myt1 Kinase Induces a G2 Cell Cycle Delay by Interfering with the Intracellular Trafficking of Cdc2-Cyclin B1 Complexes | Full Text | References | PDF (2.3 MB)
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Failure of Poly(ADP-Ribose) Polymerase Cleavage by Caspases Leads to Induction of Necrosis and Enhanced Apoptosis
Zdenko Herceg & Zhao-Qi Wang
Pages: 5124-5133
Published online: 28 Mar 2023
AbstractforFailure of Poly(ADP-Ribose) Polymerase Cleavage by Caspases Leads to Induction of Necrosis and Enhanced Apoptosis | Full Text | References | PDF (1.1 MB)
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Mitogen-Activated Protein Kinase Kinase Kinase 1 Activates Androgen Receptor-Dependent Transcription and Apoptosis in Prostate Cancer
Maria T. Abreu-Martin, Ajai Chari, Andrew A. Palladino, Noah A. Craft & Charles L. Sawyers
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Published online: 28 Mar 2023
AbstractforMitogen-Activated Protein Kinase Kinase Kinase 1 Activates Androgen Receptor-Dependent Transcription and Apoptosis in Prostate Cancer | Full Text | References | PDF (2 MB)
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PIC-1/SUMO-1-Modified PML-Retinoic Acid Receptor α Mediates Arsenic Trioxide-Induced Apoptosis in Acute Promyelocytic Leukemia
Thomas Sternsdorf, Elena Puccetti, Kirsten Jensen, Dieter Hoelzer, Hans Will, Oliver Gerhard Ottmann & Martin Ruthardt
Pages: 5170-5178
Published online: 28 Mar 2023
AbstractforPIC-1/SUMO-1-Modified PML-Retinoic Acid Receptor α Mediates Arsenic Trioxide-Induced Apoptosis in Acute Promyelocytic Leukemia | Full Text | References | PDF (1.4 MB)
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The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids
Brian W. Howell, Lorene M. Lanier, Ronald Frank, Frank B. Gertler & Jonathan A. Cooper
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Published online: 28 Mar 2023
AbstractforThe Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids | Full Text | References | PDF (1.3 MB)
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Published online: 28 Mar 2023
AbstractforCritical Role Played by Cyclin D3 in the MyoD-Mediated Arrest of Cell Cycle during Myoblast Differentiation | Full Text | References | PDF (2.1 MB)
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Dna Dynamics and Chromosome Structure

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A RAG1 and RAG2 Tetramer Complex Is Active in Cleavage in V(D)J Recombination
Tu Bailin, Xianming Mo & Moshe J. Sadofsky
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Published online: 28 Mar 2023
AbstractforA RAG1 and RAG2 Tetramer Complex Is Active in Cleavage in V(D)J Recombination | Full Text | References | PDF (1.7 MB)
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A Uve1p-Mediated Mismatch Repair Pathway in Schizosaccharomyces pombe
Balveen Kaur, J. Lee A. Fraser, Greg A. Freyer, Scott Davey & Paul W. Doetsch
Pages: 4703-4710
Published online: 28 Mar 2023
AbstractforA Uve1p-Mediated Mismatch Repair Pathway in Schizosaccharomyces pombe | Full Text | References | PDF (1,003.4 KB)
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Removal of Frameshift Intermediates by Mismatch Repair Proteins in Saccharomyces cerevisiae
Brian D. Harfe & Sue Jinks-Robertson
Pages: 4766-4773
Published online: 28 Mar 2023
AbstractforRemoval of Frameshift Intermediates by Mismatch Repair Proteins in Saccharomyces cerevisiae | Full Text | References | PDF (127.3 KB)
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Use of a Recombination Reporter Insert To Define Meiotic Recombination Domains on Chromosome III of Saccharomyces cerevisiae
Valérie Borde, Tzu-Chen Wu & Michael Lichten
Pages: 4832-4842
Published online: 28 Mar 2023
AbstractforUse of a Recombination Reporter Insert To Define Meiotic Recombination Domains on Chromosome III of Saccharomyces cerevisiae | Full Text | References | PDF (619.2 KB)
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Transcriptional Activity and Chromatin Structure of Enhancer-Deleted rRNA Genes in Saccharomyces cerevisiae
Michael Banditt, Theo Koller & José M. Sogo
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Published online: 28 Mar 2023
AbstractforTranscriptional Activity and Chromatin Structure of Enhancer-Deleted rRNA Genes in Saccharomyces cerevisiae | Full Text | References | PDF (702.2 KB)
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Atm Inactivation Results in Aberrant Telomere Clustering during Meiotic Prophase
Tej K. Pandita, Christoph H. Westphal, Melanie Anger, Satin G. Sawant, Charles R. Geard, Raj K. Pandita & Harry Scherthan
Pages: 5096-5105
Published online: 28 Mar 2023
AbstractforAtm Inactivation Results in Aberrant Telomere Clustering during Meiotic Prophase | Full Text | References | PDF (2.3 MB)
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Defects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation
Jean-Paul Javerzat, Gordon McGurk, Gwen Cranston, Christian Barreau, Pascal Bernard, Colin Gordon & Robin Allshire
Pages: 5155-5165
Published online: 28 Mar 2023
AbstractforDefects in Components of the Proteasome Enhance Transcriptional Silencing at Fission Yeast Centromeres and Impair Chromosome Segregation | Full Text | References | PDF (2.6 MB)
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Article
Sister Chromatid Exchanges Are Mediated by Homologous Recombination in Vertebrate Cells
Eiichiro Sonoda, Masao S. Sasaki, Ciaran Morrison, Yuko Yamaguchi-Iwai, Minoru Takata & Shunichi Takeda
Pages: 5166-5169
Published online: 28 Mar 2023
AbstractforSister Chromatid Exchanges Are Mediated by Homologous Recombination in Vertebrate Cells | Full Text | References | PDF (321.8 KB)
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Author's Correction

Correction
The Putative Nucleic Acid Helicase Sen1p Is Required for Formation and Stability of Termini and for Maximal Rates of Synthesis and Levels of Accumulation of Small Nucleolar RNAs in Saccharomyces cerevisiae
Page: 5235
Published online: 28 Mar 2023
CitationforThe Putative Nucleic Acid Helicase Sen1p Is Required for Formation and Stability of Termini and for Maximal Rates of Synthesis and Levels of Accumulation of Small Nucleolar RNAs in Saccharomyces cerevisiae | Full Text | PDF (18.8 KB)
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Free Access
Correction
Protein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72
Page: 5235
Published online: 28 Mar 2023
CitationforProtein-Damaging Stresses Activate c-Jun N-Terminal Kinase via Inhibition of Its Dephosphorylation: a Novel Pathway Controlled by HSP72 | Full Text | PDF (18.8 KB)
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