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Molecular and Cellular Biology Volume 19, 1999 - Issue 7
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Transcriptional Regulation

Highly Divergent Lentiviral Tat Proteins Activate Viral Gene Expression by a Common Mechanism

Paul D. BieniaszDepartment of Genetics and Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina27710
,
Therese A. GrdinaDepartment of Genetics and Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina27710
,
Hal P. BogerdDepartment of Genetics and Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina27710
&
Bryan R. CullenDepartment of Genetics and Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina27710Correspondence[email protected]
Pages 4592-4599 | Received 23 Feb 1999, Accepted 30 Mar 1999, Published online: 28 Mar 2023

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Mitchell E. Garber, Timothy P. Mayall, Eric M. Suess, Jill Meisenhelder, Nancy E. Thompson & Katherine A. Jones. (2000) CDK9 Autophosphorylation Regulates High-Affinity Binding of the Human Immunodeficiency Virus Type 1 Tat–P-TEFb Complex to TAR RNA. Molecular and Cellular Biology 20:18, pages 6958-6969.
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David H. Price. (2000) P-TEFb, a Cyclin-Dependent Kinase Controlling Elongation by RNA Polymerase II. Molecular and Cellular Biology 20:8, pages 2629-2634.
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Articles from other publishers (32)

Koh Fujinaga. (2020) P-TEFb as A Promising Therapeutic Target. Molecules 25:4, pages 838.
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Xue-Feng Wang, Bowen Bai, Yuezhi Lin, Ting Qi, Cheng Du, Mingxin Song & Xiaojun Wang. (2019) High-Efficiency Rescue of Equine Infectious Anemia Virus from a CMV-Driven Infectious Clone. Virologica Sinica 34:6, pages 725-728.
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Cheng Du, Jian Ma, Qiang Liu, Yun-Fei Li, Xi-Jun He, Yue-Zhi Lin, Xue-Feng Wang, Qing-Wen Meng, Xiaojun Wang & Jian-Hua Zhou. (2015) Mice transgenic for equine cyclin T1 and ELR1 are susceptible to equine infectious anemia virus infection. Retrovirology 12:1.
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Pengfei Wang, Xiying Qu, Xin Zhou, Yinzhong Shen, Haiyan Ji, Zheng Fu, Junxiao Deng, Panpan Lu, Wenbo Yu, Hongzhou Lu & Huanzhang Zhu. (2015) Two cellular microRNAs, miR-196b and miR-1290, contribute to HIV-1 latency. Virology 486, pages 228-238.
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Makoto Yamamoto, Hiroshi Onogi, Isao Kii, Suguru Yoshida, Kei Iida, Hiroyuki Sakai, Minako Abe, Toshiaki Tsubota, Nobutoshi Ito, Takamitsu Hosoya & Masatoshi Hagiwara. (2014) CDK9 inhibitor FIT-039 prevents replication of multiple DNA viruses. Journal of Clinical Investigation 124:8, pages 3479-3488.
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Daniel C. FarleyRichard BannisterMarie A. Leroux-CarlucciNerys E. EvansJames E. MiskinKyriacos A. Mitrophanous. (2012) Development of an Equine-Tropic Replication-Competent Lentivirus Assay for Equine Infectious Anemia Virus-Based Lentiviral Vectors. Human Gene Therapy Methods 23:5, pages 309-323.
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Rajesh Ramakrishnan, Karen Chiang, Hongbing Liu, Sona Budhiraja, Hart Donahue & Andrew P. Rice. (2012) Making a Short Story Long: Regulation of P-TEFb and HIV-1 Transcriptional Elongation in CD4+ T Lymphocytes and Macrophages. Biology 1:1, pages 94-115.
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Hanna-Mari Tervo & Oliver T. Keppler. (2010) High Natural Permissivity of Primary Rabbit Cells for HIV-1, with a Virion Infectivity Defect in Macrophages as the Final Replication Barrier. Journal of Virology 84:23, pages 12300-12314.
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Baoshan Zhang & Ronald C. Montelaro. (2009) Replication of Equine Infectious Anemia Virus in Engineered Mouse NIH 3T3 Cells. Journal of Virology 83:4, pages 2034-2037.
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Kanchan Anand, Antje Schulte, Karin Vogel-Bachmayr, Klaus Scheffzek & Matthias Geyer. (2008) Structural insights into the Cyclin T1–Tat–TAR RNA transcription activation complex from EIAV. Nature Structural & Molecular Biology 15:12, pages 1287-1292.
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J Miskin, D Chipchase, J Rohll, G Beard, T Wardell, D Angell, H Roehl, D Jolly, S Kingsman & K Mitrophanous. (2005) A replication competent lentivirus (RCL) assay for equine infectious anaemia virus (EIAV)-based lentiviral vectors. Gene Therapy 13:3, pages 196-205.
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Lars H. Lund, Britta Wahren & Mariano A. Garcia-Blanco. (2003) A functional genetic approach suggests a novel interaction between the human immunodeficiency virus type 1 (HIV-1) Tat protein and HIV-1 TAR RNA in vivo. Journal of General Virology 84:3, pages 603-606.
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Daisuke Shima, Masato Yugami, Michiko Tatsuno, Tadashi Wada, Yuki Yamaguchi & Hiroshi Handa. (2003) Mechanism of H-8 inhibition of Cyclin-dependent kinase 9: study using inhibitor-immobilized matrices. Genes to Cells 8:3, pages 215-223.
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Claudio Brigati, Mauro Giacca, Douglas M Noonan & Adriana Albini. (2003) HIV Tat, its TARgets and the control of viral gene expression. FEMS Microbiology Letters 220:1, pages 57-65.
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Jirong Bai, Jianhua Sui, Rui Ying Zhu, Aimée St. Clair Tallarico, Francesca Gennari, Dongsheng Zhang & Wayne A. Marasco. (2003) Inhibition of Tat-mediated Transactivation and HIV-1 Replication by Human Anti-hCyclinT1 Intrabodies. Journal of Biological Chemistry 278:3, pages 1433-1442.
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Li-Ying Liou, Christine H. Herrmann & Andrew P. Rice. (2002) Transient Induction of Cyclin T1 during Human Macrophage Differentiation Regulates Human Immunodeficiency Virus Type 1 Tat Transactivation Function. Journal of Virology 76:21, pages 10579-10587.
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Takeshi Kurosu, Tetsu Mukai, Satoshi Komoto, Madiha S. Ibrahim, Yong-gang Li, Takeshi Kobayashi, Shoutaro Tsuji & Kazuyoshi Ikuta. (2002) Human Immunodeficiency Virus Type 1 Subtype C Exhibits Higher Transactivation Activity of Tat than Subtypes B and E. Microbiology and Immunology 46:11, pages 787-799.
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Chao Zhou & Tariq M Rana. (2002) A Bimolecular Mechanism of HIV-1 Tat Protein Interaction with RNA Polymerase II Transcription Elongation Complexes. Journal of Molecular Biology 320:5, pages 925-942.
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Juan Martin-Serrano, Kelvin Li & Paul D. Bieniasz. (2002) Cyclin T1 Expression Is Mediated by a Complex and Constitutively Active Promoter and Does Not Limit Human Immunodeficiency Virus Type 1 Tat Function in Unstimulated Primary Lymphocytes. Journal of Virology 76:1, pages 208-219.
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Jonathan B. Rohll, Kyriacos A. Mitrophanous, Enca Martin-Rendon, Fiona M. Ellard, Pippa A. Radcliffe, Nicholas D. Mazarakis & Susan M. Kingsman. 2002. Gene Therapy Methods. Gene Therapy Methods 466 500 .
Meisheng Zhou, Sergei Nekhai, Diana C. Bharucha, Ajit Kumar, Hui Ge, David H. Price, Jean-Marc Egly & John N. Brady. (2001) TFIIH Inhibits CDK9 Phosphorylation during Human Immunodeficiency Virus Type 1 Transcription. Journal of Biological Chemistry 276:48, pages 44633-44640.
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Sheng-Hao Chao & David H. Price. (2001) Flavopiridol Inactivates P-TEFb and Blocks Most RNA Polymerase II Transcription in Vivo. Journal of Biological Chemistry 276:34, pages 31793-31799.
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Robert Hines & Wendy Maury. (2001) DH82 cells: a macrophage cell line for the replication and study of equine infectious anemia virus. Journal of Virological Methods 95:1-2, pages 47-56.
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Sheng-Hao Chao, Koh Fujinaga, Jon E. Marion, Ran Taube, Edward A. Sausville, Adrian M. Senderowicz, B. Matija Peterlin & David H. Price. (2000) Flavopiridol Inhibits P-TEFb and Blocks HIV-1 Replication. Journal of Biological Chemistry 275:37, pages 28345-28348.
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Carlos Suñé, Aaron C. Goldstrohm, Junmin Peng, David H. Price & Mariano A. Garcia-Blanco. (2000) An In Vitro Transcription System that Recapitulates Equine Infectious Anemia Virus Tat-Mediated Inhibition of Human Immunodeficiency Virus Type 1 Tat Activity Demonstrates a Role for Positive Transcription Elongation Factor b and Associated Proteins in the Mechanism of Tat Activation. Virology 274:2, pages 356-366.
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Matjaz Barboric, Ran Taube, Nada Nekrep, Koh Fujinaga & B. Matija Peterlin. (2000) Binding of Tat to TAR and Recruitment of Positive Transcription Elongation Factor b Occur Independently in Bovine Immunodeficiency Virus. Journal of Virology 74:13, pages 6039-6044.
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Aviva Lapidot & Alexander Litovchick. (2000) Novel HIV Tat antagonists. Drug Development Research 50:3-4, pages 502-515.
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Hal P. Bogerd, Heather L. Wiegand, Paul D. Bieniasz & Bryan R. Cullen. (2000) Functional Differences between Human and Bovine Immunodeficiency Virus Tat Transcription Factors. Journal of Virology 74:10, pages 4666-4671.
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Todd R. Albrecht, Lars H. Lund & Mariano A. Garcia-Blanco. (2000) Canine Cyclin T1 Rescues Equine Infectious Anemia Virus Tat Trans-Activation in Human Cells. Virology 268:1, pages 7-11.
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Wendy Maury, Sarahann Bradley, Brent Wright & Robert Hines. (2000) Cell Specificity of the Transcription-Factor Repertoire Used by a Lentivirus: Motifs Important for Expression of Equine Infectious Anemia Virus in Nonmonocytic Cells. Virology 267:2, pages 267-278.
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Ran Taube, Koh Fujinaga, Dan Irwin, Jörg Wimmer, Matthias Geyer & B. Matija Peterlin. (2000) Interactions between Equine Cyclin T1, Tat, and TAR Are Disrupted by a Leucine-to-Valine Substitution Found in Human Cyclin T1. Journal of Virology 74:2, pages 892-898.
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Ran Taube, Koh Fujinaga, Joerg Wimmer, Matjaz Barboric & B.Matija Peterlin. (1999) Tat Transactivation: A Model for the Regulation of Eukaryotic Transcriptional Elongation. Virology 264:2, pages 245-253.
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