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Molecular and Cellular Biology Volume 19, 1999 - Issue 7
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Cell Growth and Development

BRCA1 Is Phosphorylated at Serine 1497 In Vivo at a Cyclin-Dependent Kinase 2 Phosphorylation Site

Heinz RuffnerThe Salk Institute, La Jolla, California92037
,
Wei JiangThe Salk Institute, La Jolla, California92037
,
A. Grey CraigThe Salk Institute, La Jolla, California92037
,
Tony HunterThe Salk Institute, La Jolla, California92037
&
Inder M. VermaThe Salk Institute, La Jolla, California92037Correspondence[email protected]
Pages 4843-4854 | Received 06 Jan 1999, Accepted 26 Mar 1999, Published online: 28 Mar 2023

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Donato F. Romagnolo, Ryan B. Chirnomas, Jennifer Ku, Brandon D. Jeffy, Claire M. Payne, Hana Holubec, Lois Ramsey, Harris Bernstein, Carol Bernstein, Kathleen Kunke, Achyut Bhattacharyya, James Warneke & Harinder Garewal. (2003) Deoxycholate, an Endogenous Tumor Promoter and DNA Damaging Agent, Modulates BRCA-1 Expression in Apoptosis-Sensitive Epithelial Cells: Loss of BRCA-1 Expression in Colonic Adenocarcinomas. Nutrition and Cancer 46:1, pages 82-92.
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Tiho Miralem & Hava Karsenty Avraham. (2003) Extracellular Matrix Enhances Heregulin-Dependent BRCA1 Phosphorylation and Suppresses BRCA1 Expression through Its C Terminus. Molecular and Cellular Biology 23:2, pages 579-593.
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Bing Hu, Jayashree Mitra, Sander van den Heuvel & Greg H. Enders. (2001) S and G2 Phase Roles for Cdk2 Revealed by Inducible Expression of a Dominant-Negative Mutant in Human Cells. Molecular and Cellular Biology 21:8, pages 2755-2766.
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Paz Arizti, Li Fang, Iha Park, Yuxin Yin, Ellen Solomon, Toru Ouchi, Stuart A. Aaronson & Sam W. Lee. (2000) Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression. Molecular and Cellular Biology 20:20, pages 7450-7459.
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Jinyu Li, Jörg Vervoorts, Paolo Carloni, Giulia Rossetti & Bernhard Lüscher. (2017) Structural prediction of the interaction of the tumor suppressor p27KIP1 with cyclin A/CDK2 identifies a novel catalytically relevant determinant. BMC Bioinformatics 18:1.
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S. Liang, S. R. Esswein, T. Ochi, Q. Wu, D. B. Ascher, D. Chirgadze, B. L. Sibanda & T. L. Blundell. (2016) Achieving selectivity in space and time with DNA double-strand-break response and repair: molecular stages and scaffolds come with strings attached. Structural Chemistry 28:1, pages 161-171.
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Leonardo K. Teixeira & Steven I. Reed. 2017. DNA Replication. DNA Replication 527 547 .
Patrick E. Gygli, Joshua C. Chang, Hamza N. Gokozan, Fay P. Catacutan, Theresa A. Schmidt, Behiye Kaya, Mustafa Goksel, Faisal S. Baig, Shannon Chen, Amelie Griveau, Wojciech Michowski, Michael Wong, Kamalakannan Palanichamy, Piotr Sicinski, Randy J. Nelson, Catherine Czeisler & José J. Otero. (2016) Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging 8:7, pages 1540-1570.
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K. Luo, M. Deng, Y. Li, C. Wu, Z. Xu, J. Yuan & Z. Lou. (2015) CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase. Nucleic Acids Research 43:11, pages 5465-5475.
Crossref
Liam Cornell, Neil Johnson & Geoffrey I. Shapiro. 2015. PARP Inhibitors for Cancer Therapy. PARP Inhibitors for Cancer Therapy 413 430 .
R Drost & J Jonkers. (2013) Opportunities and hurdles in the treatment of BRCA1-related breast cancer. Oncogene 33:29, pages 3753-3763.
Crossref
Lu Wang, Wenjing Liu, Weidong Zhao, Gendi Song, Guishuan Wang, Xiaorong Wang & Fei Sun. (2014) Phosphorylation of CDK2 on Threonine 160 Influences Silencing of Sex Chromosome During Male Meiosis1. Biology of Reproduction 90:6.
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Eric Tram, Sevtap Savas & Hilmi Ozcelik. (2013) Missense Variants of Uncertain Significance (VUS) Altering the Phosphorylation Patterns of BRCA1 and BRCA2. PLoS ONE 8:5, pages e62468.
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Carla Manuela Abreu, Ramesh Kumar, Danielle Hamilton, Andrew William Dawdy, Kevin Creavin, Sarah Eivers, Karen Finn, Jeremy Lynn Balsbaugh, Rosemary O'Connor, Patrick A. Kiely, Jeffrey Shabanowitz, Donald F. Hunt, Muriel Grenon & Noel Francis Lowndes. (2013) Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1. PLoS Genetics 9:4, pages e1003310.
Crossref
Karen Finn, Noel Francis Lowndes & Muriel Grenon. (2011) Eukaryotic DNA damage checkpoint activation in response to double-strand breaks. Cellular and Molecular Life Sciences 69:9, pages 1447-1473.
Crossref
Hyo Jin Kang, Young Bin Hong, Hee Jeong Kim, Antai Wang & Insoo Bae. (2012) Bioactive food components prevent carcinogenic stress via Nrf2 activation in BRCA1 deficient breast epithelial cells. Toxicology Letters 209:2, pages 154-160.
Crossref
Suhwan Chang, Rui-Hong Wang, Keiko Akagi, Kyung-Ae Kim, Betty K Martin, Luca Cavallone, Diana C Haines, Mark Basik, Phuong Mai, Elizabeth Poggi, Claudine Isaacs, Lai M Looi, Kein S Mun, Mark H Greene, Stephen W Byers, Soo H Teo, Chu-Xia Deng & Shyam K Sharan. (2011) Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155. Nature Medicine 17:10, pages 1275-1282.
Crossref
Tomohiko Ohta, Ko Sato & Wenwen Wu. (2011) The BRCA1 ubiquitin ligase and homologous recombination repair. FEBS Letters 585:18, pages 2836-2844.
Crossref
Said Akli, Carolyn S. Van Pelt, Tuyen Bui, Laurent Meijer & Khandan Keyomarsi. (2011) Cdk2 is Required for Breast Cancer Mediated by the Low-Molecular-Weight Isoform of Cyclin E. Cancer Research 71:9, pages 3377-3386.
Crossref
Ian Hammond-Martel, Helen Pak, Helen Yu, Raphael Rouget, Andrew A. Horwitz, Jeffrey D. Parvin, Elliot A. Drobetsky & El Bachir Affar. (2010) PI 3 Kinase Related Kinases-Independent Proteolysis of BRCA1 Regulates Rad51 Recruitment during Genotoxic Stress in Human Cells. PLoS ONE 5:11, pages e14027.
Crossref
Antonio Cerqueira, David Santamaría, Bárbara Martínez-Pastor, Miriam Cuadrado, Oscar Fernández-Capetillo & Mariano Barbacid. (2009) Overall Cdk activity modulates the DNA damage response in mammalian cells. Journal of Cell Biology 187:6, pages 773-780.
Crossref
Suhwan Chang, Kajal Biswas, Betty K. Martin, Stacey Stauffer & Shyam K. Sharan. (2009) Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations. Journal of Clinical Investigation 119:10, pages 3160-3171.
Crossref
Neil Johnson, Dongpo Cai, Richard D. Kennedy, Shailja Pathania, Mansi Arora, Yu-Chen Li, Alan D. D'Andrea, Jeffrey D. Parvin & Geoffrey I. Shapiro. (2009) Cdk1 Participates in BRCA1-Dependent S Phase Checkpoint Control in Response to DNA Damage. Molecular Cell 35:3, pages 327-339.
Crossref
Alberto Viera, Julio S. Rufas, Inés Martínez, José L. Barbero, Sagrario Ortega & José A. Suja. (2009) CDK2 is required for proper homologous pairing, recombination and sex-body formation during male mouse meiosis. Journal of Cell Science 122:12, pages 2149-2159.
Crossref
Malinee PongsaveeVichanan YamkamonSumana DakengPornchai O-CharoenratDuncan R. SmithGrady F. SaundersPimpicha Patmasiriwat. (2009) The BRCA1 3′-UTR: 5711+421T/T_5711+1286T/T Genotype Is a Possible Breast and Ovarian Cancer Risk Factor . Genetic Testing and Molecular Biomarkers 13:3, pages 307-317.
Crossref
Marc S. Cortese, Vladimir N. Uversky & A. Keith Dunker. (2008) Intrinsic disorder in scaffold proteins: Getting more from less. Progress in Biophysics and Molecular Biology 98:1, pages 85-106.
Crossref
Chia-Ying Yang, Chao-Hui Chang, Ya-Ling Yu, Tsu-Chun Emma Lin, Sheng-An Lee, Chueh-Chuan Yen, Jinn-Moon Yang, Jin-Mei Lai, Yi-Ren Hong, Tzu-Ling Tseng, Kun-Mao Chao & Chi-Ying F. Huang. (2008) PhosphoPOINT: a comprehensive human kinase interactome and phospho-protein database. Bioinformatics 24:16, pages i14-i20.
Crossref
Dana Branzei & Marco Foiani. (2008) Regulation of DNA repair throughout the cell cycle. Nature Reviews Molecular Cell Biology 9:4, pages 297-308.
Crossref
Zuzana Bencokova, Laurianne Pauron, Clément Devic, Aurélie Joubert, Jérôme Gastaldo, Catherine Massart, Jacques Balosso & Nicolas Foray. (2007) Molecular and cellular response of the most extensively used rodent glioma models to radiation and/or cisplatin. Journal of Neuro-Oncology 86:1, pages 13-21.
Crossref
K Kehn, R Berro, A Alhaj, M E Bottazzi, W-I Yeh, Z Klase, R Van Duyne, S Fu & F Kashanchi. (2007) Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells. Oncogene 26:35, pages 5060-5069.
Crossref
Andrew J. Deans, Kum Kum Khanna, Carolyn J. McNees, Ciro Mercurio, Jörg Heierhorst & Grant A. McArthur. (2006) Cyclin-Dependent Kinase 2 Functions in Normal DNA Repair and Is a Therapeutic Target in BRCA1-Deficient Cancers. Cancer Research 66:16, pages 8219-8226.
Crossref
A. Keith Dunker, Marc S. Cortese, Pedro Romero, Lilia M. Iakoucheva & Vladimir N. Uversky. (2005) Flexible nets. The roles of intrinsic disorder in protein interaction networks. FEBS Journal 272:20, pages 5129-5148.
Crossref
Marianne Santaguida & Alain Nepveu. (2005) Differential Regulation of CDP/Cux p110 by Cyclin A/Cdk2 and Cyclin A/Cdk1. Journal of Biological Chemistry 280:38, pages 32712-32721.
Crossref
Atish D. Choudhury, Hong Xu, Ami P. Modi, Wenzhu Zhang, Thomas Ludwig & Richard Baer. (2005) Hyperphosphorylation of the BARD1 Tumor Suppressor in Mitotic Cells. Journal of Biological Chemistry 280:26, pages 24669-24679.
Crossref
Chun Shik Park, Sung Il Kim, Mi Su Lee, Cho-ya Youn, Dae Joong Kim, Eek-hoon Jho & Woo Keun Song. (2004) Modulation of β-Catenin Phosphorylation/Degradation by Cyclin-dependent Kinase 2. Journal of Biological Chemistry 279:19, pages 19592-19599.
Crossref
Kimberly A Brown, Richard L Roberts, Carlos L Arteaga & Brian K Law. (2004) Transforming growth factor-β induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein. Breast Cancer Research 6:2.
Crossref
Eliot M Rosen, Saijun Fan, Richard G Pestell & Itzhak D Goldberg. (2003) BRCA1 in hormone-responsive cancers. Trends in Endocrinology & Metabolism 14:8, pages 378-385.
Crossref
Susan A Krum, James E Womack & Timothy F Lane. (2003) Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity. Oncogene 22:38, pages 6032-6044.
Crossref
Thomas R Berton, Takashi Matsumoto, Angustias Page, Claudio J Conti, Chu-Xia Deng, José L Jorcano & David G Johnson. (2003) Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues. Oncogene 22:35, pages 5415-5426.
Crossref
N K Dhillon & M Mudryj. (2003) Cyclin E overexpression enhances cytokine-mediated apoptosis in MCF7 breast cancer cells. Genes & Immunity 4:5, pages 336-342.
Crossref
Eliot M. Rosen, Saijun Fan, Richard G. Pestell & Itzhak D. Goldberg. (2003) BRCA1 gene in breast cancer. Journal of Cellular Physiology 196:1, pages 19-41.
Crossref
Richard C. Gregory, Toshiyasu Taniguchi & Alan D. D’Andrea. (2003) Regulation of the Fanconi anemia pathway by monoubiquitination. Seminars in Cancer Biology 13:1, pages 77-82.
Crossref
Shinya Okada & Toru Ouchi. (2003) Cell Cycle Differences in DNA Damage-induced BRCA1 Phosphorylation Affect Its Subcellular Localization. Journal of Biological Chemistry 278:3, pages 2015-2020.
Crossref
Antony M Carr. (2002) DNA structure dependent checkpoints as regulators of DNA repair. DNA Repair 1:12, pages 983-994.
Crossref
Toshiyasu TaniguchiIrene Garcia-HigueraPaul R. AndreassenRichard C. GregoryMarkus GrompeAlan D. D'Andrea. (2002) S-phase–specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood 100:7, pages 2414-2420.
Crossref
Dianne C. Daniel. (2002) Highlight: BRCA1 and BRCA2 proteins in breast cancer. Microscopy Research and Technique 59:1, pages 68-83.
Crossref
Chu-Xia Deng. (2002) Roles of BRCA1 in centrosome duplication. Oncogene 21:40, pages 6222-6227.
Crossref
Betsy Bove, Roland Dunbrack & Andrew Godwin. 2002. Breast Cancer. Breast Cancer 555 624 .
Navdeep K Dhillon & Maria Mudryj. (2002) Ectopic expression of cyclin E in estrogen responsive cells abrogates antiestrogen mediated growth arrest. Oncogene 21:30, pages 4626-4634.
Crossref
Thomas Caspari, Johanne M. Murray & Antony M. Carr. (2002) Cdc2–cyclin B kinase activity links Crb2 and Rqh1–topoisomerase III. Genes & Development 16:10, pages 1195-1208.
Crossref
Ralph Scully & Nadine Puget. (2002) BRCA1 and BRCA2 in hereditary breast cancer. Biochimie 84:1, pages 95-102.
Crossref
Ingrid A. Hedenfalk, Markus Ringnér, Jeffrey M. Trent & Ake Borg. 2002. 1 34 .
Steven G Brodie, Xiaoling Xu, Wenhui Qiao, Wen-Mei Li, Liu Cao & Chu-Xia Deng. (2001) Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice. Oncogene 20:51, pages 7514-7523.
Crossref
Qiang Wang, Hongtao Zhang, Shawn Guerrette, Jinqiu Chen, Anthony Mazurek, Teresa Wilson, Artur Slupianek, Tomasz Skorski, Richard Fishel & Mark I Greene. (2001) Adenosine nucleotide modulates the physical interaction between hMSH2 and BRCA1. Oncogene 20:34, pages 4640-4649.
Crossref
Brian J Orelli, John M Logsdon Jr & Douglas K Bishop. (2001) Nine novel conserved motifs in BRCA1 identified by the chicken orthologue. Oncogene 20:32, pages 4433-4438.
Crossref
Christopher S Gilbert, Catherine M Green & Noel F Lowndes. (2001) Budding Yeast Rad9 Is an ATP-Dependent Rad53 Activating Machine. Molecular Cell 8:1, pages 129-136.
Crossref
Heinz Ruffner, Claudio A. P. Joazeiro, Dan Hemmati, Tony Hunter & Inder M. Verma. (2001) Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proceedings of the National Academy of Sciences 98:9, pages 5134-5139.
Crossref
Irene Garcia-Higuera, Toshiyasu Taniguchi, Shridar Ganesan, M.Stephen Meyn, Cynthia Timmers, James Hejna, Markus Grompe & Alan D D'Andrea. (2001) Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway. Molecular Cell 7:2, pages 249-262.
Crossref
Tamas I. Orban & Edith Olah. (2001) Expression Profiles of BRCA1 Splice Variants in Asynchronous and in G1/S Synchronized Tumor Cell Lines. Biochemical and Biophysical Research Communications 280:1, pages 32-38.
Crossref
Qiang Wang, Hongtao Zhang, Richard Fishel & Mark I Greene. (2000) BRCA1 and cell signaling. Oncogene 19:53, pages 6152-6158.
Crossref
Randal S. Tibbetts, David Cortez, Kathryn M. Brumbaugh, Ralph Scully, David Livingston, Stephen J. Elledge & Robert T. Abraham. (2000) Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes & Development 14:23, pages 2989-3002.
Crossref
K. Sankaranarayanan & R. Chakraborty. (2000) Ionizing radiation and genetic risks. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 453:2, pages 129-181.
Crossref
Jiyong Zhao, Brian K. Kennedy, Brandon D. Lawrence, David A. Barbie, A. Gregory Matera, Jonathan A. Fletcher & Ed Harlow. (2000) NPAT links cyclin E–Cdk2 to the regulation of replication-dependent histone gene transcription. Genes & Development 14:18, pages 2283-2297.
Crossref
Chu-Xia Deng & Steven G. Brodie. (2000) Roles of BRCA1 and its interacting proteins. BioEssays 22:8, pages 728-737.
Crossref
J. LiuM.D. HebertY. YeD.J. TempletonH. KungA.G. Matera. (2000) Cell cycle-dependent localization of the CDK2-cyclin E complex in Cajal (coiled) bodies. Journal of Cell Science 113:9, pages 1543-1552.
Crossref
Jong-Soo Lee, Kimberly M. Collins, Alexandra L. Brown, Chang-Hun Lee & Jay H. Chung. (2000) hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 404:6774, pages 201-204.
Crossref
Piri L Welcsh, Kelly N Owens & Mary-Claire King. (2000) Insights into the functions of BRCA1 and BRCA2. Trends in Genetics 16:2, pages 69-74.
Crossref
T. CASPARI, C. DAVIES & A.M. CARR. (2000) Analysis of the Fission Yeast Checkpoint Rad Proteins. Cold Spring Harbor Symposia on Quantitative Biology 65:0, pages 451-456.
Crossref
David CortezYi WangJun QinStephen J. Elledge. (1999) Requirement of ATM-Dependent Phosphorylation of Brca1 in the DNA Damage Response to Double-Strand Breaks. Science 286:5442, pages 1162-1166.
Crossref
Ashok R. Venkitaraman. (1999) Breast Cancer Genes and DNA Repair. Science 286:5442, pages 1100-1102.
Crossref

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