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Cell Growth and Development

Distinct Glucocorticoid Receptor Transcriptional Regulatory Surfaces Mediate the Cytotoxic and Cytostatic Effects of Glucocorticoids

Inez Rogatsky1 Department of Microbiology and the Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, New York10016
,
Adam B. Hittelman1 Department of Microbiology and the Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, New York10016
,
David Pearce2 Departments of Medicine and Cellular and Molecular Pharmacology, University of California—San Francisco, San Francisco, California94143
&
Michael J. Garabedian1 Department of Microbiology and the Kaplan Comprehensive Cancer Center, New York University School of Medicine, New York, New York10016Correspondence[email protected]
Pages 5036-5049 | Received 24 Nov 1998, Accepted 01 Apr 1999, Published online: 28 Mar 2023

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Ronit Vogt Sionov, Rachel Spokoini, Shlomit Kfir‐Erenfeld, Orly Cohen & Eitan Yefenof. 2008. 127 248 .
Claudine G James, Veronica Ulici, Jan Tuckermann, T Michael Underhill & Frank Beier. (2007) Expression profiling of Dexamethasone-treated primary chondrocytes identifies targets of glucocorticoid signalling in endochondral bone development. BMC Genomics 8:1.
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Crossref
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Crossref
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Crossref
Derek N. LaveryIain J. Mcewan. (2005) Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations. Biochemical Journal 391:3, pages 449-464.
Crossref
H.A.N. Al-Wadei, T. Takahasi & H.M. Schuller. (2005) PKA-dependent growth stimulation of cells derived from human pulmonary adenocarcinoma and small airway epithelium by dexamethasone. European Journal of Cancer 41:17, pages 2745-2753.
Crossref
V.C. Dhulipala, K.K. Maddali, W.V. Welshons & C.S. Reddy. (2005) Secalonic acid D blocks embryonic palatal mesenchymal cell-cycle by altering the activity of CDK2 and the expression of p21 and cyclin E. Birth Defects Research Part B: Developmental and Reproductive Toxicology 74:3, pages 233-242.
Crossref
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Crossref
Olga Frankfurt & Steven T Rosen. (2004) Mechanisms of glucocorticoid-induced apoptosis in hematologic malignancies: updates. Current Opinion in Oncology 16:6, pages 553-563.
Crossref
Joanna E. Chivers, Lisa M. Cambridge, Matthew C. Catley, Judith C. Mak, Louise E. Donnelly, Peter J. Barnes & Robert Newton. (2004) Differential effects of RU486 reveal distinct mechanisms for glucocorticoid repression of prostaglandin E2 release. European Journal of Biochemistry 271:20, pages 4042-4052.
Crossref
Jingbo Zhao, William A Bauman, Ruojun Huang, Avrom J Caplan & Christopher Cardozo. (2004) Oxandrolone blocks glucocorticoid signaling in an androgen receptor-dependent manner. Steroids 69:5, pages 357-366.
Crossref
M J Ausserlechner, P Obexer, G Böck, S Geley & R Kofler. (2003) Cyclin D3 and c-MYC control glucocorticoid-induced cell cycle arrest but not apoptosis in lymphoblastic leukemia cells. Cell Death & Differentiation 11:2, pages 165-174.
Crossref
V.M. Heine, S. Maslam, M. Joëls & P.J. Lucassen. (2004) Increased P27KIP1 protein expression in the dentate gyrus of chronically stressed rats indicates G1 arrest involvement. Neuroscience 129:3, pages 593-601.
Crossref
Zhen Wang & Michael J. Garabedian. (2003) Modulation of Glucocorticoid Receptor Transcriptional Activation, Phosphorylation, and Growth Inhibition by p27Kip1. Journal of Biological Chemistry 278:51, pages 50897-50901.
Crossref
Inez Rogatsky, Jen-Chywan Wang, Mika K. Derynck, Daisuke F. Nonaka, Daniel B. Khodabakhsh, Christopher M. Haqq, Beatrice D. Darimont, Michael J. Garabedian & Keith R. Yamamoto. (2003) Target-specific utilization of transcriptional regulatory surfaces by the glucocorticoid receptor. Proceedings of the National Academy of Sciences 100:24, pages 13845-13850.
Crossref
Karolien De Bosscher, Wim Vanden Berghe & Guy Haegeman. (2003) The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression. Endocrine Reviews 24:4, pages 488-522.
Crossref
Roberta Tse, Bertha A. Marroquin, Delbert R. Dorscheid & Steven R. White. (2003) β-Adrenergic agonists inhibit corticosteroid-induced apoptosis of airway epithelial cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 285:2, pages L393-L404.
Crossref
Björn Kauppi, Clarissa Jakob, Mathias Färnegårdh, Jie Yang, Harri Ahola, Maria Alarcon, Karin Calles, Owe Engström, John Harlan, Steven Muchmore, Anna-Karin Ramqvist, Susanne Thorell, Lars Öhman, Jonathan Greer, Jan-Åke Gustafsson, Jan Carlstedt-Duke & Mats Carlquist. (2003) The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain. Journal of Biological Chemistry 278:25, pages 22748-22754.
Crossref
Irina V Budunova, Dariusz Kowalczyk, Paloma Pérez, Ya Juan Yao, José L Jorcano & Thomas J Slaga. (2003) Glucocorticoid receptor functions as a potent suppressor of mouse skin carcinogenesis. Oncogene 22:21, pages 3279-3287.
Crossref
Steven R. White & Delbert R. Dorscheid. (2002) Corticosteroid-Induced Apoptosis of Airway Epithelium*. Chest 122:6, pages 278S-284S.
Crossref
Hiroko Inoue, Takako Furukawa, Stavros Giannakopoulos, Sharleen Zhou, David S. King & Naoko Tanese. (2002) Largest Subunits of the Human SWI/SNF Chromatin-remodeling Complex Promote Transcriptional Activation by Steroid Hormone Receptors. Journal of Biological Chemistry 277:44, pages 41674-41685.
Crossref
Alissa K. Greenberg, Jing Hu, Sharmila Basu, John Hay, Joan Reibman, Ting-an Yie, Kam Meng Tchou-Wong, William N. Rom & Theodore C. Lee. (2002) Glucocorticoids Inhibit Lung Cancer Cell Growth through Both the Extracellular Signal-Related Kinase Pathway and Cell Cycle Regulators. American Journal of Respiratory Cell and Molecular Biology 27:3, pages 320-328.
Crossref
J.H Davies, B.A.J Evans, M.E.M Jenney & J.W Gregory. (2002) In vitro effects of combination chemotherapy on osteoblasts: implications for osteopenia in childhood malignancy. Bone 31:2, pages 319-326.
Crossref
Tomas Kucera, Mary Waltner-Law, Donald K. Scott, Ratna Prasad & Daryl K. Granner. (2002) A Point Mutation of the AF2 Transactivation Domain of the Glucocorticoid Receptor Disrupts Its Interaction with Steroid Receptor Coactivator 1. Journal of Biological Chemistry 277:29, pages 26098-26102.
Crossref
Christophe Crochemore, Theologos M. Michaelidis, Dieter Fischer, Jean‐Philippe Loeffler & Osborne F. X. Almeida. (2002) Enhancement of p53 activity and inhibition of neural cell proliferation by glucocorticoid receptor activation. The FASEB Journal 16:8, pages 761-770.
Crossref
Elisheva Smith, Gerhard A. Coetzee & Baruch Frenkel. (2002) Glucocorticoids Inhibit Cell Cycle Progression in Differentiating Osteoblasts via Glycogen Synthase Kinase-3β. Journal of Biological Chemistry 277:20, pages 18191-18197.
Crossref
Murray A. Raskind, Charles W. Wilkinson & Elaine R. Peskind. 2002. Hormones, Brain and Behavior. Hormones, Brain and Behavior 637 664 .
Vincent Laudet & Hinrich Gronemeyer. 2002. The Nuclear Receptor FactsBook. The Nuclear Receptor FactsBook 345 367 .
P. R. Mittelstadt, J. Galon, D. Franchimont, J. J. O’Shea & J. D. Ashwell. 2002. Recent Advances in Glucocorticoid Receptor Action. Recent Advances in Glucocorticoid Receptor Action 319 339 .
I. Kudawara, T. Ueda, H. Yoshikawa, T. Miyama, T. Yamamoto & Y. Nishizawa. (2001) In vivo inhibition of tumour growth by dexamethasone in murine osteosarcomas. European Journal of Cancer 37:13, pages 1703-1708.
Crossref
Paramjeet Singh, Siew Wee Chan & Wanjin Hong. (2001) Retinoblastoma Protein Is Functionally Distinct from Its Homologues in Affecting Glucocorticoid Receptor-mediated Transcription and Apoptosis. Journal of Biological Chemistry 276:17, pages 13762-13770.
Crossref
R. Cameron & G. Feuer. (2001) The Effect of Drugs and Toxins on the Process of Apoptosis. Drug Metabolism and Drug Interactions 18:1, pages 1-32.
Crossref
Yunxia Tao, Cheryll Williams-Skipp & Robert I. Scheinman. (2001) Mapping of Glucocorticoid Receptor DNA Binding Domain Surfaces Contributing to Transrepression of NF-κB and Induction of Apoptosis. Journal of Biological Chemistry 276:4, pages 2329-2332.
Crossref
Robert A Mitchell & Richard Bucala. (2000) Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF). Seminars in Cancer Biology 10:5, pages 359-366.
Crossref
Elisheva Smith, Rebecca A. Redman, Christopher R. Logg, Gerhard A. Coetzee, Nori Kasahara & Baruch Frenkel. (2000) Glucocorticoids Inhibit Developmental Stage-specific Osteoblast Cell Cycle. Journal of Biological Chemistry 275:26, pages 19992-20001.
Crossref

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