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Qiuyu Pang, Lu You, Xiangmin Meng, Yumeng Li, Tian Deng, Deyong Li & Bingmei Zhu. (2023) Regulation of the JAK/STAT signaling pathway: The promising targets for cardiovascular disease. Biochemical Pharmacology 213, pages 115587.
Crossref
Crossref
Arturo Valle-Mendiola, Adriana Gutiérrez-Hoya & Isabel Soto-Cruz. (2023) JAK/STAT Signaling and Cervical Cancer: From the Cell Surface to the Nucleus. Genes 14:6, pages 1141.
Crossref
Crossref
Libing Hong, Yongqi Lin, Xiongyi Yang, Tong Wu, Yuxi Zhang, Zhuohang Xie, Jieli Yu, Hejia Zhao, Guoguo Yi & Min Fu. (2022) A Narrative Review of STAT Proteins in Diabetic Retinopathy: From Mechanisms to Therapeutic Prospects. Ophthalmology and Therapy 11:6, pages 2005-2026.
Crossref
Crossref
Grace L. Wong, Sara G. Manore, Daniel L. Doheny & Hui-Wen Lo. (2022) STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges. Seminars in Cancer Biology 86, pages 84-106.
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Crossref
Xin Li, Wenkai Jiang, Shi Dong, Wancheng Li, Weixiong Zhu & Wence Zhou. (2022) STAT3 Inhibitors: A Novel Insight for Anticancer Therapy of Pancreatic Cancer. Biomolecules 12:10, pages 1450.
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Crossref
Jianbiao Zhou & Wee-Joo Chng. (2022) Biological Hallmarks and Emerging Strategies to Target STAT3 Signaling in Multiple Myeloma. Cells 11:6, pages 941.
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Crossref
Nagendra Awasthi, Clifford Liongue & Alister C. Ward. (2021) STAT proteins: a kaleidoscope of canonical and non-canonical functions in immunity and cancer. Journal of Hematology & Oncology 14:1.
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Crossref
Cheol-Jung Lee, Hyun-Jung An, Eun Suh Cho, Han Chang Kang, Joo Young Lee, Hye Suk Lee & Yong-Yeon Cho. (2020) Stat2 stability regulation: an intersection between immunity and carcinogenesis. Experimental & Molecular Medicine 52:9, pages 1526-1536.
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Crossref
Julian Gräb & Thorsten Berg. (2020) The Selectivity of Fosfosal for STAT5b over STAT5a is Mediated by Arg566 in the Linker Domain. ChemBioChem 21:16, pages 2264-2267.
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Sameer Bahal, Maha E. Houssen, Ania Manson, Lorena Lorenzo, Mark A. Russell, Noel G. Morgan, Fariba Tahami & Sofia Grigoriadou. (2019) Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity. Case Reports in Immunology 2019, pages 1-5.
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Hyeri Jang, Hyejin Ko, Kwangho Song & Yeong Kim. (2019) A Sesquiterpenoid from Farfarae Flos Induces Apoptosis of MDA-MB-231 Human Breast Cancer Cells through Inhibition of JAK–STAT3 Signaling. Biomolecules 9:7, pages 278.
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Julian Gräb, Angela Berg, Linda Blechschmidt, Barbara Klüver, Stefan Rubner, Darwin Y. Fu, Jens Meiler, Martin Gräber & Thorsten Berg. (2019) The STAT5b Linker Domain Mediates the Selectivity of Catechol Bisphosphates for STAT5b over STAT5a. ACS Chemical Biology 14:4, pages 796-805.
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Su Jun Lim & Willis X. Li. 2018. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules
5170
5175
.
Kei-ichiro Arimoto, Sara Löchte, Samuel A Stoner, Christoph Burkart, Yue Zhang, Sayuri Miyauchi, Stephan Wilmes, Jun-Bao Fan, Jürgen J Heinisch, Zhi Li, Ming Yan, Sandra Pellegrini, Frédéric Colland, Jacob Piehler & Dong-Er Zhang. (2017) STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling. Nature Structural & Molecular Biology 24:3, pages 279-289.
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Uddalak Bharadwaj, T. Kris Eckols, Xuejun Xu, Moses M. Kasembeli, Yunyun Chen, Makoto Adachi, Yongcheng Song, Qianxing Mo, Stephen Y. Lai & David J. Tweardy. (2016) Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma. Oncotarget 7:18, pages 26307-26330.
Crossref
Crossref
Su Jun Lim & Willis X. Li. 2016. Encyclopedia of Signaling Molecules. Encyclopedia of Signaling Molecules
1
5
.
Claudia MertensBhagwattie HaripalSebastian Klinge & James E. Darnell. (2015) Mutations in the linker domain affect phospho-STAT3 function and suggest targets for interrupting STAT3 activity. Proceedings of the National Academy of Sciences 112:48, pages 14811-14816.
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Bin Cai, Jian-ping Cai, Yu-long Luo, Cheng Chen & Sen Zhang. (2015) The Specific Roles of JAK/STAT Signaling Pathway in Sepsis. Inflammation 38:4, pages 1599-1608.
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Mehrdad Sobhkhez, Astrid Skjesol, Ernst Thomassen, Linn Greiner Tollersrud, Dimitar B. Iliev, Baojian Sun, Børre Robertsen & Jorunn B. Jørgensen. (2014) Structural and functional characterization of salmon STAT1, STAT2 and IRF9 homologs sheds light on interferon signaling in teleosts. FEBS Open Bio 4:1, pages 858-871.
Crossref
Crossref
Florence Baudin & Christoph W. Müller. 2013. JAK-STAT Signalling. JAK-STAT Signalling
301
317
.
Stephanie Boisson-Dupuis, Xiao-Fei Kong, Satoshi Okada, Sophie Cypowyj, Anne Puel, Laurent Abel & Jean-Laurent Casanova. (2012) Inborn errors of human STAT1: allelic heterogeneity governs the diversity of immunological and infectious phenotypes. Current Opinion in Immunology 24:4, pages 364-378.
Crossref
Crossref
Cristina Isabel Santos & Ana P. Costa-Pereira. (2011) Signal transducers and activators of transcription—from cytokine signalling to cancer biology. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1816:1, pages 38-49.
Crossref
Crossref
Yong-Sik Bong, Hyun-Shik Lee, Laura Carim-Todd, Kathleen Mood, Tagvor G. Nishanian, Lino Tessarollo & Ira O. Daar. (2007) ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3. Proceedings of the National Academy of Sciences 104:44, pages 17305-17310.
Crossref
Crossref
James W. Darnowski, Frederick A. Goulette, Ying-jie Guan, Devasis Chatterjee, Zhong-Fa Yang, Leslie P. Cousens & Y. Eugene Chin. (2006) Stat3 Cleavage by Caspases. Journal of Biological Chemistry 281:26, pages 17707-17717.
Crossref
Crossref
Oliver H. Krämer, Daniela Baus, Shirley K. Knauer, Stefan Stein, Elke Jäger, Roland H. Stauber, Manuel Grez, Edith Pfitzner & Thorsten Heinzel. (2006) Acetylation of Stat1 modulates NF-κB activity. Genes & Development 20:4, pages 473-485.
Crossref
Crossref
Cheh Peng Lim & Xinmin Cao. (2006) Structure, function, and regulation of STAT proteins. Molecular BioSystems 2:11, pages 536.
Crossref
Crossref
Weifeng XuJayasree S. NairAjay MalhotraJ. Jillian Zhang. (2005) B Cell Antigen Receptor Signaling Enhances IFN-γ-Induced Stat1 Target Gene Expression Through Calcium Mobilization and Activation of Multiple Serine Kinase Pathways. Journal of Interferon & Cytokine Research 25:2, pages 113-124.
Crossref
Crossref
Soo ok Lee & Allen C. Gao. 2005.
333
357
.
Kirsi Paukku & Olli Silvennoinen. (2004) STATs as critical mediators of signal transduction and transcription: lessons learned from STAT5. Cytokine & Growth Factor Reviews 15:6, pages 435-455.
Crossref
Crossref
Tobias N. Dechow, Laura Pedranzini, Andrea Leitch, Kenneth Leslie, William L. Gerald, Irina Linkov & Jacqueline F. Bromberg. (2004) Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C. Proceedings of the National Academy of Sciences 101:29, pages 10602-10607.
Crossref
Crossref
Qian Gao, Jian Hua, Rich Kimura, Jeffery J. Headd, Xin-yuan Fu & Y. Eugene Chin. (2004) Identification of the Linker-SH2 Domain of STAT as the Origin of the SH2 Domain Using Two-dimensional Structural Alignment. Molecular & Cellular Proteomics 3:7, pages 704-714.
Crossref
Crossref
Natalia Zakharova, Elena S. Lymar, Edward Yang, Sohail Malik, J.Jillian Zhang, Robert G. Roeder & James E. DarnellJr.Jr.. (2003) Distinct Transcriptional Activation Functions of STAT1α and STAT1β on DNA and Chromatin Templates. Journal of Biological Chemistry 278:44, pages 43067-43073.
Crossref
Crossref
Edward Yang, Lorena Lerner, Daniel Besser & James E. DarnellJr.Jr.. (2003) Independent and Cooperative Activation of Chromosomal c-fos Promoter by STAT3. Journal of Biological Chemistry 278:18, pages 15794-15799.
Crossref
Crossref
J. D. MacMicking & J. D. McKinney. 2003. The Macrophage as Therapeutic Target. The Macrophage as Therapeutic Target
409
457
.
Clara Lubeseder-Martellato, Eric Guenzi, Anita Jörg, Kristin Töpolt, Elisabeth Naschberger, Elisabeth Kremmer, Christian Zietz, Erwin Tschachler, Peter Hutzler, Martin Schwemmle, Kathrin Matzen, Thomas Grimm, Barbara Ensoli & Michael Stürzl. (2002) Guanylate-Binding Protein-1 Expression Is Selectively Induced by Inflammatory Cytokines and Is an Activation Marker of Endothelial Cells during Inflammatory Diseases. The American Journal of Pathology 161:5, pages 1749-1759.
Crossref
Crossref
Melissa A. Henriksen, Aurel Betz, Marc V. Fuccillo & James E. DarnellJr.Jr.. (2002) Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site. Genes & Development 16:18, pages 2379-2389.
Crossref
Crossref
Tong Zhang, Kah Tong Seow, Chin Thing Ong & Xinmin Cao. (2002) Interdomain Interaction of Stat3 Regulates Its Src Homology 2 Domain-mediated Receptor Binding Activity. Journal of Biological Chemistry 277:20, pages 17556-17563.
Crossref
Crossref
Jayasree S. Nair, Christopher J. DaFonseca, Agneta Tjernberg, Wei Sun, James E. DarnellJr.Jr., Brian T. Chait & J. Jillian Zhang. (2002)
Requirement of Ca
2+
and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ
. Proceedings of the National Academy of Sciences 99:9, pages 5971-5976.
Crossref
Crossref
Edward Yang, Melissa A. Henriksen, Olaf Schaefer, Natalia Zakharova & James E. DarnellJr.Jr.. (2002) Dissociation Time from DNA Determines Transcriptional Function in a STAT1 Linker Mutant. Journal of Biological Chemistry 277:16, pages 13455-13462.
Crossref
Crossref
T Kisseleva, S Bhattacharya, J Braunstein & C.W Schindler. (2002) Signaling through the JAK/STAT pathway, recent advances and future challenges. Gene 285:1-2, pages 1-24.
Crossref
Crossref
Aurel Betz, Nina Lampen, Sebastian Martinek, Michael W. Young & James E. DarnellJr.Jr.. (2001)
A
Drosophila
PIAS homologue negatively regulates
stat92E
. Proceedings of the National Academy of Sciences 98:17, pages 9563-9568.
Crossref
Crossref
Amado Salvador Pena. (2001) What have we learned from the biological therapies in ulcerative colitis?. The American Journal of Gastroenterology 96:6, pages 1681-1684.
Crossref
Crossref
Yuhong Shen & James E. DarnellJr.Jr.. (2001) Antiviral Response in Cells Containing Stat1 with Heterologous Transactivation Domains. Journal of Virology 75:6, pages 2627-2633.
Crossref
Crossref
Jacqueline F. Bromberg. (2001) Activation of STAT proteins and growth control. BioEssays 23:2, pages 161-169.
Crossref
Crossref
Curt M Horvath. (2000) STAT proteins and transcriptional responses to extracellular signals. Trends in Biochemical Sciences 25:10, pages 496-502.
Crossref
Crossref
Walter D. Sotero-EstevaDarin WolfeMary FerrisMilton W. Taylor. (2000) An Indoleamine 2,3-Dioxygenase-Negative Mutant Is Defective in Stat1 DNA Binding: Differential Response to IFN-γ and IFN-α. Journal of Interferon & Cytokine Research 20:7, pages 623-632.
Crossref
Crossref
Jacqueline Bromberg & James E Darnell. (2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19:21, pages 2468-2473.
Crossref
Crossref
Moitreyee Chatterjee-Kishore, Focco van den Akker & George R Stark. (2000) Association of STATs with relatives and friends. Trends in Cell Biology 10:3, pages 106-111.
Crossref
Crossref