23
Views
106
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Direct Association and Nuclear Import of the Hepatitis B Virus X Protein with the NF-κB Inhibitor IκBα

, , , , , , & show all
Pages 6345-6354 | Received 02 Feb 1999, Accepted 27 May 1999, Published online: 27 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Na Xie, Xiang Chen, Tao Zhang, Bo Liu & Canhua Huang. (2014) Using proteomics to identify the HBx interactome in hepatitis B virus: how can this inform the clinic?. Expert Review of Proteomics 11:1, pages 59-74.
Read now
Yong-Song Guan, Qing He, Ming-Quan Wang & Ping Li. (2008) Nuclear factor kappa B and hepatitis viruses. Expert Opinion on Therapeutic Targets 12:3, pages 265-280.
Read now
Soo-Ho Choi, Kyu-Jin Park, Byung-Yoon Ahn, Guhung Jung, Michael M. C. Lai & Soon B. Hwang. (2006) Hepatitis C Virus Nonstructural 5B Protein Regulates Tumor Necrosis Factor Alpha Signaling through Effects on Cellular IκB Kinase. Molecular and Cellular Biology 26:8, pages 3048-3059.
Read now
Gulam Waris, Kyung-Won Huh & Aleem Siddiqui. (2001) Mitochondrially Associated Hepatitis B Virus X Protein Constitutively Activates Transcription Factors STAT-3 and NF-κB via Oxidative Stress. Molecular and Cellular Biology 21:22, pages 7721-7730.
Read now

Articles from other publishers (102)

Anja Schollmeier, Mirco Glitscher & Eberhard Hildt. (2023) Relevance of HBx for Hepatitis B Virus-Associated Pathogenesis. International Journal of Molecular Sciences 24:5, pages 4964.
Crossref
Manjita Srivastava, Prudhvi Lal Bhukya, Muneesh Kumar Barman, Neha Bhise & Kavita S. Lole. (2023) Modulation of cellular autophagy by genotype 1 hepatitis E virus ORF3 protein. Journal of General Virology 104:2.
Crossref
Qi Wei, Hongxiao Song, Yanli Gao, Fengchao Xu, Qingfei Xiao, Fei Wang, Bingxin Lei, Junqi Niu, Pujun Gao, Haichun Ma & Guangyun Tan. (2022) Dual-Role of Cholesterol‐25‐Hydroxylase in Regulating Hepatitis B Virus Infection and Replication. mBio 13:3.
Crossref
Ivona Nečasová, Martin Stojaspal, Edita Motyčáková, Tomáš Brom, Tomáš Janovič & Ctirad Hofr. (2022) Transcriptional regulators of human oncoviruses: structural and functional implications for anticancer therapy. NAR Cancer 4:1.
Crossref
Sergio Hernández, Francisca Álvarez-Astudillo, Daniel Garrido, Cristian Prieto, Alejandra Loyola & Rodrigo A. Villanueva. (2021) Canonical and Divergent N-Terminal HBx Isoform Proteins Unveiled: Characteristics and Roles during HBV Replication. Biomedicines 9:11, pages 1701.
Crossref
Gulsum Ozlem Elpek. (2021) Molecular pathways in viral hepatitis-associated liver carcinogenesis: An update. World Journal of Clinical Cases 9:19, pages 4890-4917.
Crossref
Cristian Prieto, Juan Montecinos, Gustavo Jiménez, Constanza Riquelme, Daniel Garrido, Sergio Hernández, Alejandra Loyola & Rodrigo A. Villanueva. (2021) Phosphorylation of Phylogenetically Conserved Amino Acid Residues Confines HBx within Different Cell Compartments of Human Hepatocarcinoma Cells. Molecules 26:5, pages 1254.
Crossref
Mai-Huong Thi Ngo, Han-Yin Jeng, Yung-Che Kuo, Josephine Diony Nanda, Ageng Brahmadhi, Thai-Yen Ling, Te-Sheng Chang & Yen-Hua Huang. (2021) The Role of IGF/IGF-1R Signaling in Hepatocellular Carcinomas: Stemness-Related Properties and Drug Resistance. International Journal of Molecular Sciences 22:4, pages 1931.
Crossref
Jianqing Yu, Nuozhou Wang, Zhongqin Gong, Liping Liu, Shengli Yang, George Gong Chen & Paul Bo San Lai. (2020) Cytochrome P450 1A2 overcomes nuclear factor kappa B-mediated sorafenib resistance in hepatocellular carcinoma. Oncogene 40:3, pages 492-507.
Crossref
Somayeh Shokri, Shahab Mahmoudvand, Reza Taherkhani, Fatemeh Farshadpour & Farid Azizi Jalalian. (2019) Complexity on modulation of NF‐κB pathways by hepatitis B and C: A double‐edged sword in hepatocarcinogenesis. Journal of Cellular Physiology 234:9, pages 14734-14742.
Crossref
Dmytro Kornyeyev, Dhivya Ramakrishnan, Christian Voitenleitner, Christine M. Livingston, Weimei Xing, Magdeleine Hung, Hyock Joo Kwon, Simon P. Fletcher & Rudolf K. Beran. (2019) Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes. Journal of Virology 93:16.
Crossref
Aastha Jindal, Anusha Thadi & Kunwar Shailubhai. (2019) Hepatocellular Carcinoma: Etiology and Current and Future Drugs. Journal of Clinical and Experimental Hepatology 9:2, pages 221-232.
Crossref
Yuan Wang, Lei Cui, Guifang Yang, Jianbo Zhan, Liang Guo, Yu Chen, Chengpeng Fan, Dan Liu & Deyin Guo. (2019) Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO. Journal of Virology 93:2.
Crossref
Dong‐Keon Lee, Ji‐Hee Kim, Joohwan Kim, Seunghwan Choi, MinSik Park, Wonjin Park, Suji Kim, Kyu‐Sun Lee, Taesam Kim, Jiwon Jung, Yoon Kyung Choi, Kwon‐Soo Ha, Moo‐Ho Won, Timothy R. Billiar, Young‐Guen Kwon & Young‐Myeong Kim. (2018) REDD‐1 aggravates endotoxin‐induced inflammation VIA atypical NF‐κB activation . The FASEB Journal 32:8, pages 4585-4599.
Crossref
Xiao-xiao Kong, Yan-ru Lv, Li-ping Shao, Xiang-yang Nong, Guang-ling Zhang, Yi Zhang, Hong-xia Fan, Min Liu, Xin Li & Hua Tang. (2016) HBx-induced MiR-1269b in NF-κB dependent manner upregulates cell division cycle 40 homolog (CDC40) to promote proliferation and migration in hepatoma cells. Journal of Translational Medicine 14:1.
Crossref
Jun Liu, Manqi Sha, Qianfeng Wang, Yong Ma, Xiaoping Geng, Yufeng Gao, Lijie Feng, Yujun Shen & Yuxian Shen. (2015) Small ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. BMC Cancer 15:1.
Crossref
Shan Gao. (2015) Clinical relevance of hepatitis B virus variants. World Journal of Hepatology 7:8, pages 1086.
Crossref
Zaigham Abbas. (2015) Hepatitis D and hepatocellular carcinoma. World Journal of Hepatology 7:5, pages 777.
Crossref
Wan-nan Chen, Ling-ling Liu, Bo-yan Jiao, Wan-song Lin, Xin-jian Lin & Xu Lin. (2015) Hepatitis B virus X protein increases the IL-1β-induced NF-κB activation via interaction with evolutionarily conserved signaling intermediate in Toll pathways (ECSIT). Virus Research 195, pages 236-245.
Crossref
Sohrab Boozarpour, Mansour Mashreghi & Mahdi Mirahmadi. (2014) Mechanisms of hepatitis B virus-induced hepatocellular carcinoma. Reviews in Medical Microbiology 25:1, pages 20-25.
Crossref
Samuel Martín-Vílchez, Ricardo Moreno-Otero & Paloma Sanz-Cameno. (2013) Mecanismos de acción y efectos de la proteína X (HBx) en la patogenia de la hepatitis crónica B. Medicina Clínica 140:11, pages 508-513.
Crossref
Ambreen Ayub, Usman Ali Ashfaq & Asma Haque. (2013) HBV Induced HCC: Major Risk Factors from Genetic to Molecular Level. BioMed Research International 2013, pages 1-14.
Crossref
Junseong Park, Wonseok Kang, Seung-Wook Ryu, Woo-Il Kim, Dong-Yeop Chang, Dong Ho Lee, Do Youn Park, Youn-Hee Choi, Kyungsun Choi, Eui-Cheol Shin & Chulhee Choi. (2012) Hepatitis C virus infection enhances TNFα-induced cell death via suppression of NF-κB. Hepatology 56:3, pages 831-840.
Crossref
Naama Kanarek & Yinon Ben-Neriah. (2012) Regulation of NF-κB by ubiquitination and degradation of the IκBs. Immunological Reviews 246:1, pages 77-94.
Crossref
A Arzumanyan, T Friedman, E Kotei, I O L Ng, Z Lian & M A Feitelson. (2011) Epigenetic repression of E-cadherin expression by hepatitis B virus x antigen in liver cancer. Oncogene 31:5, pages 563-572.
Crossref
Samuel Martin-Vilchez, Enrique Lara-Pezzi, Maria Trapero-Marugán, Ricardo Moreno-Otero & Paloma Sanz-Cameno. (2011) The molecular and pathophysiological implications of hepatitis B X antigen in chronic hepatitis B virus infection. Reviews in Medical Virology 21:5, pages 315-329.
Crossref
Ruchi Shukla, Jiping Yue, Maha Siouda, Tarik Gheit, Olivier Hantz, Philippe Merle, Fabien Zoulim, Vladimir Krutovskikh, Massimo Tommasino & Bakary S. Sylla. (2011) Proinflammatory cytokine TNF-α increases the stability of hepatitis B virus X protein through NF-κB signaling. Carcinogenesis 32:7, pages 978-985.
Crossref
Wen-Qing Xiang, Wen-Feng Feng, Wei Ke, Zhen Sun, Zhi Chen & Wei Liu. (2011) Hepatitis B virus X protein stimulates IL-6 expression in hepatocytes via a MyD88-dependent pathway. Journal of Hepatology 54:1, pages 26-33.
Crossref
Yu Zhou, Shuo Wang, Jing-Wei Ma, Zhang Lei, Hui-Fen Zhu, Ping Lei, Zhuo-Shun Yang, Biao Zhang, Xin-Xin Yao, Chuan Shi, Li-Fang Sun, Xiong-Wen Wu, Qin Ning, Guan-Xin Shen & Bo Huang. (2010) Hepatitis B Virus Protein X-induced Expression of the CXC Chemokine IP-10 Is Mediated through Activation of NF-κB and Increases Migration of Leukocytes. Journal of Biological Chemistry 285:16, pages 12159-12168.
Crossref
T M Bui-Nguyen, S B Pakala, R D Sirigiri, W Xia, M-C Hung, S K Sarin, V Kumar, B L Slagle & R Kumar. (2009) NF-κB signaling mediates the induction of MTA1 by hepatitis B virus transactivator protein HBx. Oncogene 29:8, pages 1179-1189.
Crossref
Amin Majdalawieh & Hyo-Sung Ro. (2010) Regulation of IB Function and NF-B Signaling: AEBP1 Is a Novel Proinflammatory Mediator in Macrophages. Mediators of Inflammation 2010, pages 1-27.
Crossref
P. Soussan & C. Le Pendeven. (2010) Virus de l'h?patite B. EMC - Biologie m?dicale 5:2, pages 1-11.
Crossref
Massimo Levrero & Laura Belloni. 2010. Signaling Pathways in Liver Diseases. Signaling Pathways in Liver Diseases 465 481 .
Yongchao He, Hongwei Zhang, Jianhua Yin, Jiaxin Xie, Xiaojie Tan, Shijian Liu, Qian Zhang, Chengzhong Li, Jun Zhao, Hongyang Wang & Guangwen Cao. (2009) IkappaBalpha gene promoter polymorphisms are associated with hepatocarcinogenesis in patients infected with hepatitis B virus genotype C. Carcinogenesis 30:11, pages 1916-1922.
Crossref
C.F. Sephton, D. Zhang, T.M. Lehmann, P.R. Pennington, M.P. Scheid & D.D. Mousseau. (2009) The nuclear localization of 3'-phosphoinositide-dependent kinase-1 is dependent on its association with the protein tyrosine phosphatase SHP-1. Cellular Signalling 21:11, pages 1634-1644.
Crossref
Kylie M. Wagstaff & David A. Jans. (2009) Importins and Beyond: Non-Conventional Nuclear Transport Mechanisms. Traffic 10:9, pages 1188-1198.
Crossref
Wei-ying Zhang, Na Cai, Li-hong Ye & Xiao-dong Zhang. (2009) Transformation of human liver L-O2 cells mediated by stable HBx transfection. Acta Pharmacologica Sinica 30:8, pages 1153-1161.
Crossref
Chul-Yong Park, Sang-Heun Oh, Sang Min Kang, Yun-Sook Lim & Soon B. Hwang. (2009) Hepatitis delta virus large antigen sensitizes to TNF-α-induced NF-κB signaling. Molecules and Cells 28:1, pages 49-55.
Crossref
Amy J. Clippinger, Tricia L. Gearhart & Michael J. Bouchard. (2009) Hepatitis B Virus X Protein Modulates Apoptosis in Primary Rat Hepatocytes by Regulating both NF-κB and the Mitochondrial Permeability Transition Pore. Journal of Virology 83:10, pages 4718-4731.
Crossref
Man-Young Cha, Dong-Kyun Ryu, Hyeon-Sik Jung, Ho-Eun Chang & Wang-Shick Ryu. (2009) Stimulation of hepatitis B virus genome replication by HBx is linked to both nuclear and cytoplasmic HBx expression. Journal of General Virology 90:4, pages 978-986.
Crossref
Shirine Benhenda, Delphine Cougot, Marie-Annick Buendia & Christine Neuveut. 2009. 75 109 .
B Sun & M Karin. (2008) NF-κB signaling, liver disease and hepatoprotective agents. Oncogene 27:48, pages 6228-6244.
Crossref
Virginie Doceul, Bryan Charleston, Helen Crooke, Elizabeth Reid, Penny P. Powell & Julian Seago. (2008) The Npro product of classical swine fever virus interacts with IκBα, the NF-κB inhibitor. Journal of General Virology 89:8, pages 1881-1889.
Crossref
Ruth Chin, Linda Earnest-Silveira, Bernd Koeberlein, Susanne Franz, Hanswalter Zentgraf, Scott Bowden, C-Thomas Bock & Joseph Torresi. (2008) Failure of Lamivudine to Reverse Hepatitis B Virus-Associated Changes in ERK, Akt and Cell Cycle Regulatory Proteins. Antiviral Therapy 13:2, pages 221-230.
Crossref
RamaKrishna Badugu, Matthew Garcia, Vimala Bondada, Aashish Joshi & James W. Geddes. (2008) N Terminus of Calpain 1 Is a Mitochondrial Targeting Sequence. Journal of Biological Chemistry 283:6, pages 3409-3417.
Crossref
Toshiyuki Kawashima & Toshio Kitamura. 2008. Small GTPases in Disease, Part B. Small GTPases in Disease, Part B 171 180 .
Gilles Despouy, Marjorie Joiner, Emilie Le Toriellec, Robert Weil & Marc Henri Stern. (2007) The TCL1 oncoprotein inhibits activation-induced cell death by impairing PKCθ and ERK pathways. Blood 110:13, pages 4406-4416.
Crossref
Hae-Ryun Um, Won-Chung Lim, Sun-Young Chae, Sun Park, Jeon Han Park & Hyeseong Cho. (2007) Raf-1 and protein kinase B regulate cell survival through the activation of NF-κB in hepatitis B virus X-expressing cells. Virus Research 125:1, pages 1-8.
Crossref
Lu Ye, Junying Qi, Gaopeng Li, Deding Tao & Shihui Song. (2007) The effect of HBx gene on the apoptosis of hepatic cells. Journal of Huazhong University of Science and Technology 27:2, pages 167-169.
Crossref
Matias A. Avila & Kun P. Lu. (2007) Hepatitis B Virus X Protein and Pin1 in Liver Cancer: “Les Liaisons Dangereuses”. Gastroenterology 132:3, pages 1180-1183.
Crossref
Mounia Chami, Bénédicte Oulès & Patrizia Paterlini-Bréchot. (2006) Cytobiological consequences of calcium-signaling alterations induced by human viral proteins. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1763:11, pages 1344-1362.
Crossref
Roberta Pang, Eric Tse & Ronnie T.P. Poon. (2006) Molecular pathways in hepatocellular carcinoma. Cancer Letters 240:2, pages 157-169.
Crossref
Ji Miao, George G. Chen, Suk-ying Chun & Paul P.S. Lai. (2006) Hepatitis B virus X protein induces apoptosis in hepatoma cells through inhibiting Bcl-xL expression. Cancer Letters 236:1, pages 115-124.
Crossref
Tzong-Hsien Lee, Dar-In Tai, Cha-Ju Cheng, Chi-Shu Sun, Ching-Yih Lin, Ming-Jen Sheu, Wei-Ping Lee, Cheng-Yuan Peng, Andrew H-J Wang & Sun-Lung Tsai. (2005) Enhanced nuclear factor-kappa B-associated Wnt-1 expression in hepatitis B- and C-related hepatocarcinogenesis: identification by functional proteomics. Journal of Biomedical Science 13:1, pages 27-39.
Crossref
Vinay Tergaonkar, Qiutang Li & Inder M. Verma. 2006. NF-κB/Rel Transcription Factor Family. NF-κB/Rel Transcription Factor Family 162 178 .
Marcello Arsura & Lakita G. Cavin. (2005) Nuclear factor-κB and liver carcinogenesis. Cancer Letters 229:2, pages 157-169.
Crossref
P. Clarke, R. L. DeBiasi, S. M. Meintzer, B. A. Robinson & K. L. Tyler. (2005) Inhibition of NF-κ B activity and cFLIP expression contribute to viral-induced apoptosis. Apoptosis 10:3, pages 513-524.
Crossref
Kerstin Reimers, Katja Buchholz & Hermann Werchau. (2005) Respiratory syncytial virus M2-1 protein induces the activation of nuclear factor kappa B. Virology 331:2, pages 260-268.
Crossref
Michael J. Bouchard & Robert J. Schneider. (2004) The Enigmatic X Gene of Hepatitis B Virus. Journal of Virology 78:23, pages 12725-12734.
Crossref
Sandra M. Mueller, Ronny Jung, Sigrid Weiler & Sabine M. Lang. (2004) Vpx proteins of SIVmac239 and HIV-2ROD interact with the cytoskeletal protein α-actinin 1. Journal of General Virology 85:11, pages 3291-3303.
Crossref
Sylvia Vlcek, Roland Foisner & Katherine L Wilson. (2004) Lco1 is a novel widely expressed lamin-binding protein in the nuclear interior. Experimental Cell Research 298:2, pages 499-511.
Crossref
Chun-Fung Chan, Tai-On Yau, Dong-Yan Jin, Chun-Ming Wong, Sheung-Tat Fan & Irene Oi-Lin Ng. (2004) Evaluation of Nuclear Factor-κB, Urokinase-Type Plasminogen Activator, and HBx and Their Clinicopathological Significance in Hepatocellular Carcinoma. Clinical Cancer Research 10:12, pages 4140-4149.
Crossref
V. Kumar & D. P. Sarkar. 2004. Transcription Factors. Transcription Factors 377 407 .
Thomas D. Gilmore. 2004. Signal Transduction in Cancer. Signal Transduction in Cancer 241 265 .
Kazuyuki Ohata, Tatsuki Ichikawa, Kazuhiko Nakao, Masaya Shigeno, Daisuke Nishimura, Hiroki Ishikawa, Keisuke Hamasaki & Katsumi Eguchi. (2003) Interferon alpha inhibits the nuclear factor kappa B activation triggered by X gene product of hepatitis B virus in human hepatoma cells. FEBS Letters 553:3, pages 304-308.
Crossref
Wen-Ling Shih, Min-Liang Kuo, Shuang-En Chuang, Ann-Lii Cheng & Shin-Lian Doong. (2003) Hepatitis B Virus X Protein Activates a Survival Signaling by Linking Src to Phosphatidylinositol 3-Kinase. Journal of Biological Chemistry 278:34, pages 31807-31813.
Crossref
Richard E Kast & Eric Lewin Altschuler. (2003) Tumor necrosis factor-alpha in hepatitis B: potential role for bupropion. Journal of Hepatology 39:1, pages 131-133.
Crossref
Rut Valgardsdottir & Hans Prydz. (2003) Transport Signals and Transcription-dependent Nuclear Localization of the Putative DEAD-box Helicase MDDX28. Journal of Biological Chemistry 278:23, pages 21146-21154.
Crossref
Penny Clarke, Suzanne M. Meintzer, Lisa A. Moffitt & Kenneth L. Tyler. (2003) Two Distinct Phases of Virus-induced Nuclear Factor κB Regulation Enhance Tumor Necrosis Factor-related Apoptosis-inducing Ligand-mediated Apoptosis in Virus-infected Cells. Journal of Biological Chemistry 278:20, pages 18092-18100.
Crossref
Robert Weil, Klaus Schwamborn, Andrés Alcover, Christine Bessia, Vincenzo Di Bartolo & Alain Israël. (2003) Induction of the NF-κB Cascade by Recruitment of the Scaffold Molecule NEMO to the T Cell Receptor. Immunity 18:1, pages 13-26.
Crossref
T. D. Gilmore & G. Mosialos. 2003. Nuclear Factor кB. Nuclear Factor кB 89 113 .
Paul J. Chiao, Ren Na, Jiangong Niu, Guido M. Sclabas, Qianggang Dong & Steven A. Curley. (2002) Role of Rel/NF-?B transcription factors in apoptosis of human hepatocellular carcinoma cells. Cancer 95:8, pages 1696-1705.
Crossref
Patricia Chastagner, Jay Reddy & Jacques Thèze. (2002) Lymphoadenopathy in IL-2-Deficient Mice: Further Characterization and Overexpression of the Antiapoptotic Molecule Cellular FLIP. The Journal of Immunology 169:7, pages 3644-3651.
Crossref
Séverine Bontron, Nathalie Lin-Marq & Michel Strubin. (2002) Hepatitis B Virus X Protein Associated with UV-DDB1 Induces Cell Death in the Nucleus and Is Functionally Antagonized by UV-DDB2. Journal of Biological Chemistry 277:41, pages 38847-38854.
Crossref
Marta Carretero, Marta Gómez-Gonzalo, Enrique Lara-Pezzi, Ignacio Benedicto, José Aramburu, Sara Martı́nez-Martı́nez, Juan Miguel Redondo & Manuel López-Cabrera. (2002) The Hepatitis B Virus X Protein Binds to and Activates the NH2-Terminal trans-Activation Domain of Nuclear Factor of Activated T Cells-1. Virology 299:2, pages 288-300.
Crossref
LAURENCE LÉVY, CLAIRE ANGÉLIQUE RENARD, YU WEI & MARIE ANNICK BUENDIA. (2006) Genetic Alterations and Oncogenic Pathways in Hepatocellular Carcinoma. Annals of the New York Academy of Sciences 963:1, pages 21-36.
Crossref
J. Guilherme Tralhao, Jean Roudier, Serban Morosan, Carlo Giannini, Hong Tu, Cyril Goulenok, Françoise Carnot, Flora Zavala, Virginie Joulin, Dina Kremsdorf & Christian Bréchot. (2002) Paracrine in vivo inhibitory effects of hepatitis B virus X protein (HBx) on liver cell proliferation: An alternative mechanism of HBx-related pathogenesis . Proceedings of the National Academy of Sciences 99:10, pages 6991-6996.
Crossref
Meir Shamay, Orr Barak, Gilad Doitsh, Israel Ben-Dor & Yosef Shaul. (2002) Hepatitis B Virus pX Interacts with HBXAP, a PHD Finger Protein to Coactivate Transcription. Journal of Biological Chemistry 277:12, pages 9982-9988.
Crossref
Nan-Shan Chang. (2002) The Non-ankyrin C Terminus of IκBα Physically Interacts with p53 in Vivo and Dissociates in Response to Apoptotic Stress, Hypoxia, DNA Damage, and Transforming Growth Factor-β1-mediated Growth Suppression. Journal of Biological Chemistry 277:12, pages 10323-10331.
Crossref
Barnabe Dossou Assogba, Byung Hyune Choi & Hyune Mo Rho. (2002) Transcriptional activation of the promoter of human cytomegalovirus immediate early gene (CMV-IE) by the hepatitis B viral X protein (HBx) through the NF-κB site. Virus Research 84:1-2, pages 171-179.
Crossref
Kyung-Won Huh & Aleem Siddiqui. (2002) Characterization of the mitochondrial association of hepatitis B virus X protein, HBx. Mitochondrion 1:4, pages 349-359.
Crossref
Eija Helin, Raija Vainionpää, Timo Hyypiä, Ilkka Julkunen & Sampsa Matikainen. (2001) Measles Virus Activates NF-κB and STAT Transcription Factors and Production of IFN-α/β and IL-6 in the Human Lung Epithelial Cell Line A549. Virology 290:1, pages 1-10.
Crossref
G.G. Chen, P.B.S. Lai, P.K.S. Chan, E.C.W. Chak, J.H.Y. Yip, R.L.K. Ho, B.C.S. Leung & W.Y. Lau. (2001) Decreased expression of Bid in human hepatocellular carcinoma is related to hepatitis B virus X protein. European Journal of Cancer 37:13, pages 1695-1702.
Crossref
Jonathan Hoare, Frank Henkler, Jason J. Dowling, William Errington, Robert D. Goldin, David Fish & Michael J. McGarvey. (2001) Subcellular localisation of the X protein in HBV infected hepatocytes. Journal of Medical Virology 64:4, pages 419-426.
Crossref
Vladimir S. Spiegelman, Pete Stavropoulos, Esther Latres, Michele Pagano, Ze'ev Ronai, Tomas J. Slaga & Serge Y. Fuchs. (2001) Induction of β-Transducin Repeat-containing Protein by JNK Signaling and Its Role in the Activation of NF-κB. Journal of Biological Chemistry 276:29, pages 27152-27158.
Crossref
Marshonna Forgues, Aizen J. Marrogi, Elisa A. Spillare, Chuan-Ging Wu, Qin Yang, Minoru Yoshida & Xin Wei Wang. (2001) Interaction of the Hepatitis B Virus X Protein with the Crm1-dependent Nuclear Export Pathway. Journal of Biological Chemistry 276:25, pages 22797-22803.
Crossref
Jingyu Diao, Robert Garces & Christopher D. Richardson. (2001) X protein of hepatitis B virus modulates cytokine and growth factor related signal transduction pathways during the course of viral infections and hepatocarcinogenesis. Cytokine & Growth Factor Reviews 12:2-3, pages 189-205.
Crossref
Hideo Yoshida, Naoya Kato, Yasushi Shiratori, Motoyuki Otsuka, Shin Maeda, Jun Kato & Masao Omata. (2001) Hepatitis C Virus Core Protein Activates Nuclear Factor κB-dependent Signaling through Tumor Necrosis Factor Receptor-associated Factor. Journal of Biological Chemistry 276:19, pages 16399-16405.
Crossref
Nicole H. PurcellChenfei YuDaoyao HeJialing XiangNir ParanJoseph A. DiDonato, Shoji Yamaoka, Yosef ShaulAnning Lin. (2001) Activation of NF-κB by hepatitis B virus X protein through an IκB kinase-independent mechanism. American Journal of Physiology-Gastrointestinal and Liver Physiology 280:4, pages G669-G677.
Crossref
Frank Henkler, Jonathan Hoare, Naushin Waseem, Robert D. Goldin, Michael J. McGarvey, Rajen Koshy & Ian A. King. (2001) Intracellular localization of the hepatitis B virus HBx protein. Journal of General Virology 82:4, pages 871-882.
Crossref
Orr Barak, Ami Aronheim & Yosef Shaul. (2001) HBV X Protein Targets HIV Tat-Binding Protein 1. Virology 283:1, pages 110-120.
Crossref
Jingyu Diao, Aye Aye Khine, Farida Sarangi, Eric Hsu, Caterina Iorio, Lee Anne Tibbles, James R. Woodgett, Josef Penninger & Christopher D. Richardson. (2001) X Protein of Hepatitis B Virus Inhibits Fas-mediated Apoptosis and Is Associated with Up-regulation of the SAPK/JNK Pathway. Journal of Biological Chemistry 276:11, pages 8328-8340.
Crossref
John Hiscott, Hakju Kwon & Pierre Génin. (2001) Hostile takeovers: viral appropriation of the NF-kB pathway. Journal of Clinical Investigation 107:2, pages 143-151.
Crossref
Fei Su, Christian N. Theodosis & Robert J. Schneider. (2001) Role of NF-κB and Myc Proteins in Apoptosis Induced by Hepatitis B Virus HBx Protein. Journal of Virology 75:1, pages 215-225.
Crossref
Shau-Feng Chang, Hans Jürgen Netter, Eberhard Hildt, Ralph SchusterStephan SchaeferYin-Chen Hsu, Andreas Rang & Hans Will. (2001) Duck Hepatitis B Virus Expresses a Regulatory HBx-Like Protein from a Hidden Open Reading Frame. Journal of Virology 75:1, pages 161-170.
Crossref
Jingbo Pan, Ling-Xun Duan, Bill S. Sun & Mark A. Feitelson. (2001) Hepatitis B virus X protein protects against anti-Fas-mediated apoptosis in human liver cells by inducing NF-κB. Journal of General Virology 82:1, pages 171-182.
Crossref
Gábor Lotz, András Kiss, Pál Kaposi Novák, Gábor Sobel & Zsuzsa Schaff. (2001) Hepatitis viruses and hepatocarcinogenesis. Journal of Physiology-Paris 95:1-6, pages 417-422.
Crossref
Delphine Sitterlin, Françoise Bergametti & Catherine Transy. (2000) UVDDB p127-binding modulates activities and intracellular distribution of Hepatitis B virus X protein. Oncogene 19:38, pages 4417-4426.
Crossref
Nan-Shan Chang, Lori Schultz & John Heath. (2000) Suppression of IκBα Expression Is Necessary for c-Jun N-Terminal Kinase-Mediated Enhancement of Fas Cytotoxicity. Biochemical and Biophysical Research Communications 274:1, pages 4-10.
Crossref
Mounia Chami, Devrim Gozuacik, Kenichi Saigo, Thierry Capiod, Pierre Falson, Hervé Lecoeur, Tetsuro Urashima, Jack Beckmann, Marie-Lyse Gougeon, Michel Claret, Marc le Maire, Christian Bréchot & Patrizia Paterlini-Bréchot. (2000) Hepatitis B virus-related insertional mutagenesis implicates SERCA1 gene in the control of apoptosis. Oncogene 19:25, pages 2877-2886.
Crossref
Christian Bréchot, Devrim Gozuacik, Yoshiki Murakami & Patrizia Paterlini-Bréchot. (2000) Molecular bases for the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Seminars in Cancer Biology 10:3, pages 211-231.
Crossref
Patrizia Paterlini-Bréchot, Mounia Chami & Devrim Gozuacik. 2000. Calcium: The Molecular Basis of Calcium Action in Biology and Medicine. Calcium: The Molecular Basis of Calcium Action in Biology and Medicine 505 519 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.