Molecular and Cellular Biology, Volume 19, Issue 9 (1999)

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Molecular and Cellular Biology, Volume 19, Issue 9 (1999)

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Article
Transcription and Growth Regulatory Functions of the HIN-200 Family of Proteins
Ricky W. Johnstone & Joseph A. Trapani
Pages: 5833-5838
Published online: 27 Mar 2023
First Page PreviewforTranscription and Growth Regulatory Functions of the HIN-200 Family of Proteins | Full Text | References | PDF (557.5 KB)
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Gene Expression

Article
Predominance of Duplicative VSG Gene Conversion in Antigenic Variation in African Trypanosomes
Nicholas P. Robinson, Nils Burman, Sara E. Melville & J. David Barry
Pages: 5839-5846
Published online: 27 Mar 2023
AbstractforPredominance of Duplicative VSG Gene Conversion in Antigenic Variation in African Trypanosomes | Full Text | References | PDF (1.4 MB)
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Article
Active-Site Mutations in the Xrn1p Exoribonuclease of Saccharomyces cerevisiae Reveal a Specific Role in Meiosis
Jachen A. Solinger, Donatella Pascolini & Wolf-Dietrich Heyer
Pages: 5930-5942
Published online: 27 Mar 2023
AbstractforActive-Site Mutations in the Xrn1p Exoribonuclease of Saccharomyces cerevisiae Reveal a Specific Role in Meiosis | Full Text | References | PDF (2 MB)
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Article
SMG-2 Is a Phosphorylated Protein Required for mRNA Surveillance in Caenorhabditis elegans and Related to Upf1p of Yeast
Michelle F. Page, Brian Carr, Kirk R. Anders, Andrew Grimson & Philip Anderson
Pages: 5943-5951
Published online: 27 Mar 2023
AbstractforSMG-2 Is a Phosphorylated Protein Required for mRNA Surveillance in Caenorhabditis elegans and Related to Upf1p of Yeast | Full Text | References | PDF (1.4 MB)
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Article
Base Pairing between U3 Small Nucleolar RNA and the 5′ End of 18S rRNA Is Required for Pre-rRNA Processing
Kishor Sharma & David Tollervey
Pages: 6012-6019
Published online: 27 Mar 2023
AbstractforBase Pairing between U3 Small Nucleolar RNA and the 5′ End of 18S rRNA Is Required for Pre-rRNA Processing | Full Text | References | PDF (957.4 KB)
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Article
Identification of cis and trans Elements Involved in the Cell Cycle Regulation of Multiple Genes in Crithidia fasciculata
Riaz Mahmood, Jane C. Hines & Dan S. Ray
Pages: 6174-6182
Published online: 27 Mar 2023
AbstractforIdentification of cis and trans Elements Involved in the Cell Cycle Regulation of Multiple Genes in Crithidia fasciculata | Full Text | References | PDF (5.1 MB)
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Article
RanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase
Peter Askjaer, Angela Bachi, Matthias Wilm, F. Ralf Bischoff, Daniel L. Weeks, Vera Ogniewski, Mutsuhito Ohno, Christof Niehrs, Jørgen Kjems, Iain W. Mattaj & Maarten Fornerod
Pages: 6276-6285
Published online: 27 Mar 2023
AbstractforRanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase | Full Text | References | PDF (942.3 KB)
  • 26 Views
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Article
Identification of Novel Import and Export Signals of Human TAP, the Protein That Binds to the Constitutive Transport Element of the Type D Retrovirus mRNAs
Jenifer Bear, Wei Tan, Andrei S. Zolotukhin, Carlos Tabernero, Eric A. Hudson & Barbara K. Felber
Pages: 6306-6317
Published online: 27 Mar 2023
AbstractforIdentification of Novel Import and Export Signals of Human TAP, the Protein That Binds to the Constitutive Transport Element of the Type D Retrovirus mRNAs | Full Text | References | PDF (1.8 MB)
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Transcriptional Regulation

Article
Functional Analysis of the SIN3-Histone Deacetylase RPD3-RbAp48-Histone H4 Connection in the Xenopus Oocyte
Danielle Vermaak, Paul A. Wade, Peter L. Jones, Yun-Bo Shi & Alan P. Wolffe
Pages: 5847-5860
Published online: 27 Mar 2023
AbstractforFunctional Analysis of the SIN3-Histone Deacetylase RPD3-RbAp48-Histone H4 Connection in the Xenopus Oocyte | Full Text | References | PDF (1.4 MB)
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Article
Histone Acetyltransferase Complexes Can Mediate Transcriptional Activation by the Major Glucocorticoid Receptor Activation Domain
Annika E. Wallberg, Kristen E. Neely, Jan-Åke Gustafsson, Jerry L. Workman, Anthony P. H. Wright & Patrick A. Grant
Pages: 5952-5959
Published online: 27 Mar 2023
AbstractforHistone Acetyltransferase Complexes Can Mediate Transcriptional Activation by the Major Glucocorticoid Receptor Activation Domain | Full Text | References | PDF (1 MB)
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Article
Tat-SF1 Protein Associates with RAP30 and Human SPT5 Proteins
Jae B. Kim, Yuki Yamaguchi, Tadashi Wada, Hiroshi Handa & Phillip A. Sharp
Pages: 5960-5968
Published online: 27 Mar 2023
AbstractforTat-SF1 Protein Associates with RAP30 and Human SPT5 Proteins | Full Text | References | PDF (884.9 KB)
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Article
Targeted Expression of the DNA Binding Domain of DRE-Binding Factor, a Drosophila Transcription Factor, Attenuates DNA Replication of the Salivary Gland and Eye Imaginal Disc
Fumiko Hirose, Masamitsu Yamaguchi & Akio Matsukage
Pages: 6020-6028
Published online: 27 Mar 2023
AbstractforTargeted Expression of the DNA Binding Domain of DRE-Binding Factor, a Drosophila Transcription Factor, Attenuates DNA Replication of the Salivary Gland and Eye Imaginal Disc | Full Text | References | PDF (1.7 MB)
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Article
Functional Analysis of the Yeast Glc7-Binding Protein Reg1 Identifies a Protein Phosphatase Type 1-Binding Motif as Essential for Repression of ADH2 Expression
Kenneth M. Dombek, Valentina Voronkova, Alexa Raney & Elton T. Young
Pages: 6029-6040
Published online: 27 Mar 2023
AbstractforFunctional Analysis of the Yeast Glc7-Binding Protein Reg1 Identifies a Protein Phosphatase Type 1-Binding Motif as Essential for Repression of ADH2 Expression | Full Text | References | PDF (639.2 KB)
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Article
The Androgen Receptor Amino-Terminal Domain Plays a Key Role in p160 Coactivator-Stimulated Gene Transcription
Philippe Alen, Frank Claessens, Guido Verhoeven, Wilfried Rombauts & Ben Peeters
Pages: 6085-6097
Published online: 27 Mar 2023
AbstractforThe Androgen Receptor Amino-Terminal Domain Plays a Key Role in p160 Coactivator-Stimulated Gene Transcription | Full Text | References | PDF (1.3 MB)
  • 32 Views
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Article
Identification by In Vivo Genomic Footprinting of a Transcriptional Switch Containing NF-κB and Sp1 That Regulates the IκBα Promoter
Michèle Algarté, Hakju Kwon, Pierre Génin & John Hiscott
Pages: 6140-6153
Published online: 27 Mar 2023
AbstractforIdentification by In Vivo Genomic Footprinting of a Transcriptional Switch Containing NF-κB and Sp1 That Regulates the IκBα Promoter | Full Text | References | PDF (3 MB)
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Article
MCM Proteins Are Associated with RNA Polymerase II Holoenzyme
K. Yankulov, I. Todorov, P. Romanowski, D. Licatalosi, K. Cilli, S. McCracken, R. Laskey & D. L. Bentley
Pages: 6154-6163
Published online: 27 Mar 2023
AbstractforMCM Proteins Are Associated with RNA Polymerase II Holoenzyme | Full Text | References | PDF (1.3 MB)
  • 35 Views
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Article
Multiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins
Han Ma, Heng Hong, Shih-Ming Huang, Ryan A. Irvine, Paul Webb, Peter J. Kushner, Gerhard A. Coetzee & Michael R. Stallcup
Pages: 6164-6173
Published online: 27 Mar 2023
AbstractforMultiple Signal Input and Output Domains of the 160-Kilodalton Nuclear Receptor Coactivator Proteins | Full Text | References | PDF (635.8 KB)
  • 25 Views
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Article
Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene
Takeshi Kawamoto, Tatsuya Sueyoshi, Igor Zelko, Rick Moore, Kimberly Washburn & Masahiko Negishi
Pages: 6318-6322
Published online: 27 Mar 2023
AbstractforPhenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the CYP2B Gene | Full Text | References | PDF (1 MB)
  • 54 Views
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Article
Activating Signal Cointegrator 1, a Novel Transcription Coactivator of Nuclear Receptors, and Its Cytosolic Localization under Conditions of Serum Deprivation
Han-Jong Kim, Ji-Young Yi, Hee-Sook Sung, David D. Moore, Byung Hak Jhun, Young Chul Lee & Jae Woon Lee
Pages: 6323-6332
Published online: 27 Mar 2023
AbstractforActivating Signal Cointegrator 1, a Novel Transcription Coactivator of Nuclear Receptors, and Its Cytosolic Localization under Conditions of Serum Deprivation | Full Text | References | PDF (585.6 KB)
  • 69 Views
  • 53 CrossRef citations
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Article
Transcriptional Activation by NF-κB Requires Multiple Coactivators
Kelly-Ann Sheppard, David W. Rose, Zaffar K. Haque, Riki Kurokawa, Eileen McInerney, Stefan Westin, Dimitris Thanos, Michael G. Rosenfeld, Christopher K. Glass & Tucker Collins
Pages: 6367-6378
Published online: 27 Mar 2023
AbstractforTranscriptional Activation by NF-κB Requires Multiple Coactivators | Full Text | References | PDF (1.5 MB)
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Article
Trithorax and ASH1 Interact Directly and Associate with the Trithorax Group-Responsive bxd Region of the Ultrabithorax Promoter
Tanya Rozovskaia, Sergei Tillib, Sheryl Smith, Yurii Sedkov, Orit Rozenblatt-Rosen, Svetlana Petruk, Takahiro Yano, Tatsuya Nakamura, Levana Ben-Simchon, John Gildea, Carlo M. Croce, Allen Shearn, Eli Canaani & Alexander Mazo
Pages: 6441-6447
Published online: 27 Mar 2023
AbstractforTrithorax and ASH1 Interact Directly and Associate with the Trithorax Group-Responsive bxd Region of the Ultrabithorax Promoter | Full Text | References | PDF (1.1 MB)
  • 9 Views
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Article
A Novel Role for Helix 12 of Retinoid X Receptor in Regulating Repression
Jinsong Zhang, Xiao Hu & Mitchell A. Lazar
Pages: 6448-6457
Published online: 27 Mar 2023
AbstractforA Novel Role for Helix 12 of Retinoid X Receptor in Regulating Repression | Full Text | References | PDF (1.2 MB)
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Cell Growth and Development

Article
Dual Role for Hsc70 in the Biogenesis and Regulation of the Heme-Regulated Kinase of the α Subunit of Eukaryotic Translation Initiation Factor 2
Sheri Uma, Vanitha Thulasiraman & Robert L. Matts
Pages: 5861-5871
Published online: 27 Mar 2023
AbstractforDual Role for Hsc70 in the Biogenesis and Regulation of the Heme-Regulated Kinase of the α Subunit of Eukaryotic Translation Initiation Factor 2 | Full Text | References | PDF (2.2 MB)
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Article
The G2 Checkpoint Is Maintained by Redundant Pathways
Tina M. Passalaris, Jennifer A. Benanti, Lindy Gewin, Tohru Kiyono & Denise A. Galloway
Pages: 5872-5881
Published online: 27 Mar 2023
AbstractforThe G2 Checkpoint Is Maintained by Redundant Pathways | Full Text | References | PDF (1.5 MB)
  • 14 Views
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Article
Protein Kinase A-Dependent and -Independent Signaling Pathways Contribute to Cyclic AMP-Stimulated Proliferation
Lisa A. Cass, Scott A. Summers, Gregory V. Prendergast, Jonathan M. Backer, Morris J. Birnbaum & Judy L. Meinkoth
Pages: 5882-5891
Published online: 27 Mar 2023
AbstractforProtein Kinase A-Dependent and -Independent Signaling Pathways Contribute to Cyclic AMP-Stimulated Proliferation | Full Text | References | PDF (1.5 MB)
  • 44 Views
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Article
Suppression of Ras-Induced Apoptosis by the Rac GTPase
Tom Joneson & Dafna Bar-Sagi
Pages: 5892-5901
Published online: 27 Mar 2023
AbstractforSuppression of Ras-Induced Apoptosis by the Rac GTPase | Full Text | References | PDF (2.1 MB)
  • 7 Views
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Article
The von Hippel-Lindau Tumor Suppressor Gene Inhibits Hepatocyte Growth Factor/Scatter Factor-Induced Invasion and Branching Morphogenesis in Renal Carcinoma Cells
Shahriar Koochekpour, Michael Jeffers, Paul H. Wang, Changning Gong, Gregory A. Taylor, Lisa M. Roessler, Robert Stearman, James R. Vasselli, William G. Stetler-Stevenson, William G. Kaelin Jr., W. Marston Linehan, Richard D. Klausner, James R. Gnarra & George F. Vande Woude
Pages: 5902-5912
Published online: 27 Mar 2023
AbstractforThe von Hippel-Lindau Tumor Suppressor Gene Inhibits Hepatocyte Growth Factor/Scatter Factor-Induced Invasion and Branching Morphogenesis in Renal Carcinoma Cells | Full Text | References | PDF (7.7 MB)
  • 16 Views
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Article
Myc Downregulation by Transforming Growth Factor β Required for Activation of the p15Ink4b G1 Arrest Pathway
Beverley J. Warner, Stacy W. Blain, Joan Seoane & Joan Massagué
Pages: 5913-5922
Published online: 27 Mar 2023
AbstractforMyc Downregulation by Transforming Growth Factor β Required for Activation of the p15Ink4b G1 Arrest Pathway | Full Text | References | PDF (3 MB)
  • 35 Views
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Article
NF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis
Cun-Yu Wang, Denis C. Guttridge, Marty W. Mayo & Albert S. Baldwin Jr.
Pages: 5923-5929
Published online: 27 Mar 2023
AbstractforNF-κB Induces Expression of the Bcl-2 Homologue A1/Bfl-1 To Preferentially Suppress Chemotherapy-Induced Apoptosis | Full Text | References | PDF (1.5 MB)
  • 45 Views
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Article
Impaired Immune Responses and B-Cell Proliferation in Mice Lacking the Id3 Gene
Lihua Pan, Shinichi Sato, Joshua P. Frederick, Xiao-Hong Sun & Yuan Zhuang
Pages: 5969-5980
Published online: 27 Mar 2023
AbstractforImpaired Immune Responses and B-Cell Proliferation in Mice Lacking the Id3 Gene | Full Text | References | PDF (1.6 MB)
  • 75 Views
  • 127 CrossRef citations
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Article
Phosphorylation-Independent Inhibition of Cdc28p by the Tyrosine Kinase Swe1p in the Morphogenesis Checkpoint
John N. McMillan, Rey A. L. Sia, Elaine S. G. Bardes & Daniel J. Lew
Pages: 5981-5990
Published online: 27 Mar 2023
AbstractforPhosphorylation-Independent Inhibition of Cdc28p by the Tyrosine Kinase Swe1p in the Morphogenesis Checkpoint | Full Text | References | PDF (944 KB)
  • 12 Views
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Article
Inhibition of Mitogen-Activated Kinase Signaling Sensitizes HeLa Cells to Fas Receptor-Mediated Apoptosis
Tim H. Holmström, Stefanie E. F. Tran, Victoria L. Johnson, Natalie G. Ahn, Sek C. Chow & John E. Eriksson
Pages: 5991-6002
Published online: 27 Mar 2023
AbstractforInhibition of Mitogen-Activated Kinase Signaling Sensitizes HeLa Cells to Fas Receptor-Mediated Apoptosis | Full Text | References | PDF (4.4 MB)
  • 20 Views
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Article
The Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Cascade Activation Is a Key Signalling Pathway Involved in the Regulation of G1 Phase Progression in Proliferating Hepatocytes
Hélène Talarmin, Claude Rescan, Sandrine Cariou, Denise Glaise, Giuliana Zanninelli, Marc Bilodeau, Pascal Loyer, Christiane Guguen-Guillouzo & Georges Baffet
Pages: 6003-6011
Published online: 27 Mar 2023
AbstractforThe Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Cascade Activation Is a Key Signalling Pathway Involved in the Regulation of G1 Phase Progression in Proliferating Hepatocytes | Full Text | References | PDF (1.3 MB)
  • 33 Views
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Article
Cell Cycle Progression and Proliferation Despite 4BP-1 Dephosphorylation
Steven O. Marx & Andrew R. Marks
Pages: 6041-6047
Published online: 27 Mar 2023
AbstractforCell Cycle Progression and Proliferation Despite 4BP-1 Dephosphorylation | Full Text | References | PDF (992.7 KB)
  • 8 Views
  • 23 CrossRef citations
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Article
E2F4 Actively Promotes the Initiation and Maintenance of Nerve Growth Factor-Induced Cell Differentiation
Stephan P. Persengiev, Ivanela I. Kondova & Daniel L. Kilpatrick
Pages: 6048-6056
Published online: 27 Mar 2023
AbstractforE2F4 Actively Promotes the Initiation and Maintenance of Nerve Growth Factor-Induced Cell Differentiation | Full Text | References | PDF (1,022.8 KB)
  • 9 Views
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Article
The Strength of Interaction at the Raf Cysteine-Rich Domain Is a Critical Determinant of Response of Raf to Ras Family Small GTPases
Tomoyo Okada, Chang-Deng Hu, Tai-Guang Jin, Ken-ichi Kariya, Yuriko Yamawaki-Kataoka & Tohru Kataoka
Pages: 6057-6064
Published online: 27 Mar 2023
AbstractforThe Strength of Interaction at the Raf Cysteine-Rich Domain Is a Critical Determinant of Response of Raf to Ras Family Small GTPases | Full Text | References | PDF (1.3 MB)
  • 20 Views
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Article
The Yeast Trimeric Guanine Nucleotide-Binding Protein α Subunit, Gpa2p, Controls the Meiosis-Specific Kinase Ime2p Activity in Response to Nutrients
Mariel Donzeau & Wolfhard Bandlow
Pages: 6110-6119
Published online: 27 Mar 2023
AbstractforThe Yeast Trimeric Guanine Nucleotide-Binding Protein α Subunit, Gpa2p, Controls the Meiosis-Specific Kinase Ime2p Activity in Response to Nutrients | Full Text | References | PDF (726.9 KB)
  • 8 Views
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Article
Regulated Expression of Focal Adhesion Kinase-Related Nonkinase, the Autonomously Expressed C-Terminal Domain of Focal Adhesion Kinase
Kate Nolan, Judith Lacoste & J. Thomas Parsons
Pages: 6120-6129
Published online: 27 Mar 2023
AbstractforRegulated Expression of Focal Adhesion Kinase-Related Nonkinase, the Autonomously Expressed C-Terminal Domain of Focal Adhesion Kinase | Full Text | References | PDF (2.2 MB)
  • 21 Views
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Article
Ectopic Expression of Cdc25A Accelerates the G1/S Transition and Leads to Premature Activation of Cyclin E- and Cyclin A-Dependent Kinases
Ida Blomberg & Ingrid Hoffmann
Pages: 6183-6194
Published online: 27 Mar 2023
AbstractforEctopic Expression of Cdc25A Accelerates the G1/S Transition and Leads to Premature Activation of Cyclin E- and Cyclin A-Dependent Kinases | Full Text | References | PDF (1.8 MB)
  • 25 Views
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Article
The Antiapoptotic Gene mcl-1 Is Up-Regulated by the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway through a Transcription Factor Complex Containing CREB
Ju-Ming Wang, Jyh-Rong Chao, Wannhsin Chen, Min-Liang Kuo, Jeffrey J.-Y. Yen & Hsin-Fang Yang-Yen
Pages: 6195-6206
Published online: 27 Mar 2023
AbstractforThe Antiapoptotic Gene mcl-1 Is Up-Regulated by the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway through a Transcription Factor Complex Containing CREB | Full Text | References | PDF (2.5 MB)
  • 43 Views
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Article
Two Inactive Fragments of the Integral RNA Cooperate To Assemble Active Telomerase with the Human Protein Catalytic Subunit (hTERT) In Vitro
Valerie M. Tesmer, Lance P. Ford, Shawn E. Holt, Bryan C. Frank, Xiaoming Yi, Dara L. Aisner, Michel Ouellette, Jerry W. Shay & Woodring E. Wright
Pages: 6207-6216
Published online: 27 Mar 2023
AbstractforTwo Inactive Fragments of the Integral RNA Cooperate To Assemble Active Telomerase with the Human Protein Catalytic Subunit (hTERT) In Vitro | Full Text | References | PDF (828.5 KB)
  • 19 Views
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Article
Grb10, a Positive, Stimulatory Signaling Adapter in Platelet-Derived Growth Factor BB-, Insulin-Like Growth Factor I-, and Insulin-Mediated Mitogenesis
Jian Wang, Heping Dai, Nasim Yousaf, Mustapha Moussaif, Youping Deng, Amale Boufelliga, O. Rama Swamy, Michelle E. Leone & Heimo Riedel
Pages: 6217-6228
Published online: 27 Mar 2023
AbstractforGrb10, a Positive, Stimulatory Signaling Adapter in Platelet-Derived Growth Factor BB-, Insulin-Like Growth Factor I-, and Insulin-Mediated Mitogenesis | Full Text | References | PDF (1.6 MB)
  • 30 Views
  • 83 CrossRef citations
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Article
Elevated Cyclin E Levels, Inactive Retinoblastoma Protein, and Suppression of the p27KIP1 Inhibitor Characterize Early Development of Promyeloid Cells into Macrophages
Qiang Liu, Roger W. VanHoy, J. H. Zhou, Robert Dantzer, Gregory G. Freund & Keith W. Kelley
Pages: 6229-6239
Published online: 27 Mar 2023
AbstractforElevated Cyclin E Levels, Inactive Retinoblastoma Protein, and Suppression of the p27KIP1 Inhibitor Characterize Early Development of Promyeloid Cells into Macrophages | Full Text | References | PDF (461.3 KB)
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Article
Role of Distinct Mitogen-Activated Protein Kinase Pathways and Cooperation between Ets-2, ATF-2, and Jun Family Members in Human Urokinase-Type Plasminogen Activator Gene Induction by Interleukin-1 and Tetradecanoyl Phorbol Acetate
Grazia Cirillo, Laura Casalino, Daniela Vallone, Anna Caracciolo, Dario De Cesare & Pasquale Verde
Pages: 6240-6252
Published online: 27 Mar 2023
AbstractforRole of Distinct Mitogen-Activated Protein Kinase Pathways and Cooperation between Ets-2, ATF-2, and Jun Family Members in Human Urokinase-Type Plasminogen Activator Gene Induction by Interleukin-1 and Tetradecanoyl Phorbol Acetate | Full Text | References | PDF (2.4 MB)
  • 8 Views
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Article
Insulin-Induced Phosphorylation and Activation of Cyclic Nucleotide Phosphodiesterase 3B by the Serine-Threonine Kinase Akt
Tadahiro Kitamura, Yukari Kitamura, Shoji Kuroda, Yasuhisa Hino, Miwa Ando, Ko Kotani, Hiroaki Konishi, Hidenori Matsuzaki, Ushio Kikkawa, Wataru Ogawa & Masato Kasuga
Pages: 6286-6296
Published online: 27 Mar 2023
AbstractforInsulin-Induced Phosphorylation and Activation of Cyclic Nucleotide Phosphodiesterase 3B by the Serine-Threonine Kinase Akt | Full Text | References | PDF (1.3 MB)
  • 89 Views
  • 274 CrossRef citations
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Article
The Ras Mutant D119N Is Both Dominant Negative and Activated
Robbert H. Cool, Gudula Schmidt, Christian U. Lenzen, Heino Prinz, Dorothee Vogt & Alfred Wittinghofer
Pages: 6297-6305
Published online: 27 Mar 2023
AbstractforThe Ras Mutant D119N Is Both Dominant Negative and Activated | Full Text | References | PDF (148.1 KB)
  • 26 Views
  • 57 CrossRef citations
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Article
Differential Roles of Akt, Rac, and Ral in R-Ras-Mediated Cellular Transformation, Adhesion, and Survival
Masako Osada, Tatyana Tolkacheva, Weiqun Li, Tung O. Chan, Philip N. Tsichlis, Rosana Saez, Alec C. Kimmelman & Andrew M.-L. Chan
Pages: 6333-6344
Published online: 27 Mar 2023
AbstractforDifferential Roles of Akt, Rac, and Ral in R-Ras-Mediated Cellular Transformation, Adhesion, and Survival | Full Text | References | PDF (1.6 MB)
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Article
Direct Association and Nuclear Import of the Hepatitis B Virus X Protein with the NF-κB Inhibitor IκBα
Robert Weil, Hüseyin Sirma, Carlo Giannini, Dina Kremsdorf, Christine Bessia, Catherine Dargemont, Christian Bréchot & Alain Israël
Pages: 6345-6354
Published online: 27 Mar 2023
AbstractforDirect Association and Nuclear Import of the Hepatitis B Virus X Protein with the NF-κB Inhibitor IκBα | Full Text | References | PDF (2.5 MB)
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Article
The Oncoprotein E2A-Pbx1a Collaborates with Hoxa9 To Acutely Transform Primary Bone Marrow Cells
Unnur Thorsteinsdottir, Jana Krosl, Evert Kroon, André Haman, Trang Hoang & Guy Sauvageau
Pages: 6355-6366
Published online: 27 Mar 2023
AbstractforThe Oncoprotein E2A-Pbx1a Collaborates with Hoxa9 To Acutely Transform Primary Bone Marrow Cells | Full Text | References | PDF (1.8 MB)
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Article
CDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase
Elena Vigo, Heiko Müller, Elena Prosperini, Guus Hateboer, Peter Cartwright, Maria Cristina Moroni & Kristian Helin
Pages: 6379-6395
Published online: 27 Mar 2023
AbstractforCDC25A Phosphatase Is a Target of E2F and Is Required for Efficient E2F-Induced S Phase | Full Text | References | PDF (2.6 MB)
  • 34 Views
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Article
Suppression of STAT5 Functions in Liver, Mammary Glands, and T Cells in Cytokine-Inducible SH2-Containing Protein 1 Transgenic Mice
Akira Matsumoto, Youichi Seki, Masato Kubo, Satoshi Ohtsuka, Asuka Suzuki, Itsuro Hayashi, Kohichiro Tsuji, Tatsutoshi Nakahata, Masaru Okabe, Shuichi Yamada & Akihiko Yoshimura
Pages: 6396-6407
Published online: 27 Mar 2023
AbstractforSuppression of STAT5 Functions in Liver, Mammary Glands, and T Cells in Cytokine-Inducible SH2-Containing Protein 1 Transgenic Mice | Full Text | References | PDF (1.9 MB)
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Article
E2F1 Has Both Oncogenic and Tumor-Suppressive Properties in a Transgenic Model
Angela M. Pierce, Robin Schneider-Broussard, Irma B. Gimenez-Conti, Jamie L. Russell, Claudio J. Conti & David G. Johnson
Pages: 6408-6414
Published online: 27 Mar 2023
AbstractforE2F1 Has Both Oncogenic and Tumor-Suppressive Properties in a Transgenic Model | Full Text | References | PDF (2 MB)
  • 7 Views
  • 112 CrossRef citations
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Article
Functional Analysis of H-Ryk, an Atypical Member of the Receptor Tyrosine Kinase Family
R. M. Katso, R. B. Russell & T. S. Ganesan
Pages: 6427-6440
Published online: 27 Mar 2023
AbstractforFunctional Analysis of H-Ryk, an Atypical Member of the Receptor Tyrosine Kinase Family | Full Text | References | PDF (14.1 MB)
  • 20 Views
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Article
Disruption of Retinoblastoma Protein Family Function by Human Papillomavirus Type 16 E7 Oncoprotein Inhibits Lens Development in Part through E2F-1
Jennifer McCaffrey, Lili Yamasaki, Nicholas J. Dyson, Ed Harlow & Anne E. Griep
Pages: 6458-6468
Published online: 27 Mar 2023
AbstractforDisruption of Retinoblastoma Protein Family Function by Human Papillomavirus Type 16 E7 Oncoprotein Inhibits Lens Development in Part through E2F-1 | Full Text | References | PDF (1.6 MB)
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Dna Dynamics and Chromosome Structure

Article
Interactions of TLC1 (Which Encodes the RNA Subunit of Telomerase), TEL1, and MEC1 in Regulating Telomere Length in the Yeast Saccharomyces cerevisiae
Kim B. Ritchie, Julia C. Mallory & Thomas D. Petes
Pages: 6065-6075
Published online: 27 Mar 2023
AbstractforInteractions of TLC1 (Which Encodes the RNA Subunit of Telomerase), TEL1, and MEC1 in Regulating Telomere Length in the Yeast Saccharomyces cerevisiae | Full Text | References | PDF (2.7 MB)
  • 35 Views
  • 197 CrossRef citations
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Article
Cleavage and Inactivation of ATM during Apoptosis
Graeme C. M. Smith, Fabrizio d’adda di Fagagna, Nicholas D. Lakin & Stephen P. Jackson
Pages: 6076-6084
Published online: 27 Mar 2023
AbstractforCleavage and Inactivation of ATM during Apoptosis | Full Text | References | PDF (2.2 MB)
  • 28 Views
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Article
Activation of Silent Replication Origins at Autonomously Replicating Sequence Elements near the HML Locus in Budding Yeast
Marija Vujcic, Charles A. Miller & David Kowalski
Pages: 6098-6109
Published online: 27 Mar 2023
AbstractforActivation of Silent Replication Origins at Autonomously Replicating Sequence Elements near the HML Locus in Budding Yeast | Full Text | References | PDF (890.7 KB)
  • 15 Views
  • 72 CrossRef citations
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Article
Analysis of Primary Structural Determinants That Distinguish the Centromere-Specific Function of Histone Variant Cse4p from Histone H3
Kevin C. Keith, Richard E. Baker, Yinhuai Chen, Kendra Harris, Sam Stoler & Molly Fitzgerald-Hayes
Pages: 6130-6139
Published online: 27 Mar 2023
AbstractforAnalysis of Primary Structural Determinants That Distinguish the Centromere-Specific Function of Histone Variant Cse4p from Histone H3 | Full Text | References | PDF (3.1 MB)
  • 12 Views
  • 66 CrossRef citations
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Article
Involvement of DNA End-Binding Protein Ku in Ty Element Retrotransposition
Jessica A. Downs & Stephen P. Jackson
Pages: 6260-6268
Published online: 27 Mar 2023
AbstractforInvolvement of DNA End-Binding Protein Ku in Ty Element Retrotransposition | Full Text | References | PDF (697.8 KB)
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Article
The Drosophila melanogaster DmRAD54 Gene Plays a Crucial Role in Double-Strand Break Repair after P-Element Excision and Acts Synergistically with Ku70 in the Repair of X-Ray Damage
Rolf Kooistra, Albert Pastink, José B. M. Zonneveld, Paul H. M. Lohman & Jan C. J. Eeken
Pages: 6269-6275
Published online: 27 Mar 2023
AbstractforThe Drosophila melanogaster DmRAD54 Gene Plays a Crucial Role in Double-Strand Break Repair after P-Element Excision and Acts Synergistically with Ku70 in the Repair of X-Ray Damage | Full Text | References | PDF (105.6 KB)
  • 15 Views
  • 42 CrossRef citations
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Article
Methylation-Mediated Transcriptional Silencing in Euchromatin by Methyl-CpG Binding Protein MBD1 Isoforms
Naoyuki Fujita, Shin-ichiro Takebayashi, Katsuzumi Okumura, Shinichi Kudo, Tsutomu Chiba, Hideyuki Saya & Mitsuyoshi Nakao
Pages: 6415-6426
Published online: 27 Mar 2023
AbstractforMethylation-Mediated Transcriptional Silencing in Euchromatin by Methyl-CpG Binding Protein MBD1 Isoforms | Full Text | References | PDF (7 MB)
  • 26 Views
  • 149 CrossRef citations
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Cell and Organelle Structure and Assembly

Article
In Vitro Import of a Nuclearly Encoded tRNA into the Mitochondrion of Trypanosoma brucei
Audra E. Yermovsky-Kammerer & Stephen L. Hajduk
Pages: 6253-6259
Published online: 27 Mar 2023
AbstractforIn Vitro Import of a Nuclearly Encoded tRNA into the Mitochondrion of Trypanosoma brucei | Full Text | References | PDF (451.2 KB)
  • 11 Views
  • 39 CrossRef citations
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Errata

Correction
Atm Inactivation Results in Aberrant Telomere Clustering during Meiotic Prophase
Page: 6469
Published online: 27 Mar 2023
CitationforAtm Inactivation Results in Aberrant Telomere Clustering during Meiotic Prophase | Full Text | PDF (15.9 KB)
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