Citations (72)
Keep up to date with the latest research on this topic with citation updates for this article.
Articles from other publishers (72)
Hannah L. Black, Rachel Livingstone, Cynthia C. Mastick, Mohammed Al Tobi, Holly Taylor, Angéline Geiser, Laura Stirrat, Dimitrios Kioumourtzoglou, John R. Petrie, James G. Boyle, Nia J. Bryant & Gwyn W. Gould. (2022) Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion. Journal of Cell Science 135:1.
Crossref
Crossref
Furong Liu, Ruyue He, Min Zhu, Lin Zhou, Yinghui Liu & Haijia Yu. (2022) Assembly-promoting protein Munc18c stimulates SNARE-dependent membrane fusion through its SNARE-like peptide. Journal of Biological Chemistry 298:10, pages 102470.
Crossref
Crossref
Jinhee Hwang & Debbie C. Thurmond. (2022) Exocytosis Proteins: Typical and Atypical Mechanisms of Action in Skeletal Muscle. Frontiers in Endocrinology 13.
Crossref
Crossref
Megan I. Brasher, Shawn C. Chafe, Paul C. McDonald, Oksana Nemirovsky, Genya Gorshtein, Zachary J. Gerbec, Wells S. Brown, Olivia R. Grafinger, Matthew Marchment, Esther Matus, Shoukat Dedhar & Marc G. Coppolino. (2022) Syntaxin4-Munc18c Interaction Promotes Breast Tumor Invasion and Metastasis by Regulating MT1-MMP Trafficking. Molecular Cancer Research 20:3, pages 434-445.
Crossref
Crossref
Mariangela Centrone, Maria De Santo, Isabella Nicotera, Cristina Labate, Marianna Ranieri, Annarita Di Mise, Maria Mola, Maria Mastrodonato, Rosangela Elliani, Riccardo Barberi, Vincenzo Formoso, Grazia Tamma & Giovanna Valenti. (2018) Gi Protein Modulation of the Potassium Channel TASK-2 Mediates Vesicle Osmotic Swelling to Facilitate the Fusion of Aquaporin-2 Water Channel Containing Vesicles. Cells 7:12, pages 276.
Crossref
Crossref
Subhankar Dolai, Tao Liang, Abrahim I. Orabi, Li Xie, Douglas Holmyard, Tanveer A. Javed, Nestor A. Fernandez, Huanli Xie, Mark S. Cattral, Debbie C. Thurmond, Peter Thorn & Herbert Y. Gaisano. (2018) Depletion of the membrane-fusion regulator Munc18c attenuates caerulein hyperstimulation–induced pancreatitis. Journal of Biological Chemistry 293:7, pages 2510-2522.
Crossref
Crossref
Ragadeepthi Tunduguru & Debbie C. Thurmond. (2017) Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out. Frontiers in Endocrinology 8.
Crossref
Crossref
Megan I. Brasher, David M. Martynowicz, Olivia R. Grafinger, Andrea Hucik, Emma Shanks-Skinner, James Uniacke & Marc G. Coppolino. (2017) Interaction of Munc18c and syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumor cells. Journal of Biological Chemistry 292:39, pages 16199-16210.
Crossref
Crossref
Sarmiza E. Stanca, Christian Matthäus, Ute Neugebauer, Sandor Nietzsche, Wolfgang Fritzsche, Jan Dellith, Rainer Heintzmann, Karina Weber, Volker Deckert, Christoph Krafft & Jürgen Popp. (2015) Chemo-spectroscopic sensor for carboxyl terminus overexpressed in carcinoma cell membrane. Nanomedicine: Nanotechnology, Biology and Medicine 11:7, pages 1831-1839.
Crossref
Crossref
Hao Xu, Matthew Grant Arnold & Sushmitha Vijay Kumar. (2015) Differential Effects of Munc18s on Multiple Degranulation-Relevant Trans-SNARE Complexes. PLOS ONE 10:9, pages e0138683.
Crossref
Crossref
Latha Ramalingam, Stephanie M. Yoder, Eunjin Oh & Debbie C. Thurmond. (2014) Munc18c: a controversial regulator of peripheral insulin action. Trends in Endocrinology & Metabolism 25:11, pages 601-608.
Crossref
Crossref
L. Amanda Sadacca, Joanne Bruno, Jennifer Wen, Wenyong Xiong & Timothy E. McGraw. (2013) Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs. Molecular Biology of the Cell 24:16, pages 2544-2557.
Crossref
Crossref
Lourdes Garrido-Sanchez, Xavier Escote, Leticia Coin-Aragüez, Jose Carlos Fernandez-Garcia, Rajaa El Bekay, Joan Vendrell, Eduardo Garcia-Fuentes & Francisco J. Tinahones. (2013) Munc18c in Adipose Tissue Is Downregulated in Obesity and Is Associated with Insulin. PLoS ONE 8:5, pages e63937.
Crossref
Crossref
Swati S. Jain, Laelie A. Snook, Jan F.C. Glatz, Joost J.F.P. Luiken, Graham P. Holloway, Debbie C. Thurmond & Arend Bonen. (2012) Munc18c provides stimulus-selective regulation of GLUT4 but not fatty acid transporter trafficking in skeletal muscle. FEBS Letters 586:16, pages 2428-2435.
Crossref
Crossref
Xiang ZHAO, Bao-Da HAN & Li-Xin LI. (2012) Function of SM protein in vesicle transport. Hereditas (Beijing) 34:4, pages 389-400.
Crossref
Crossref
Dara Leto & Alan R. Saltiel. (2012) Regulation of glucose transport by insulin: traffic control of GLUT4. Nature Reviews Molecular Cell Biology 13:6, pages 383-396.
Crossref
Crossref
Veronica Aran, Nia J Bryant & Gwyn W Gould. (2011) Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4. BMC Biochemistry 12:1.
Crossref
Crossref
Nolan J. Hoffman & Jeffrey S. Elmendorf. (2011) Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis. Trends in Endocrinology & Metabolism 22:3, pages 110-116.
Crossref
Crossref
Ren-Wang Peng, Eric Abellan & Martin Fussenegger. (2011) Differential effect of exocytic SNAREs on the production of recombinant proteins in mammalian cells. Biotechnology and Bioengineering 108:3, pages 611-620.
Crossref
Crossref
James A. McCormick & David H. Ellison. (2011) The WNKs: Atypical Protein Kinases With Pleiotropic Actions. Physiological Reviews 91:1, pages 177-219.
Crossref
Crossref
Jenna L. Jewell, Eunjin Oh & Debbie C. Thurmond. (2010) Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 298:3, pages R517-R531.
Crossref
Crossref
Shuhei Ishikura, Costin N. Antonescu & Amira Klip. (2010) Documenting GLUT4 Exocytosis and Endocytosis in Muscle Cell Monolayers. Current Protocols in Cell Biology 46:1.
Crossref
Crossref
Robert D. Burgoyne, Jeff W. Barclay, Leo F. Ciufo, Margaret E. Graham, Mark T.W. Handley & Alan Morgan. (2009) The Functions of Munc18-1 in Regulated Exocytosis. Annals of the New York Academy of Sciences 1152:1, pages 76-86.
Crossref
Crossref
June Chunqiu Hou, Le Min & Jeffrey E. Pessin. 2009. Insulin and IGFs. Insulin and IGFs
473
506
.
Fiona M. Brandie, Veronica Aran, Avani Verma, James A. McNew, Nia J. Bryant & Gwyn W. Gould. (2008) Negative Regulation of Syntaxin4/SNAP-23/VAMP2-Mediated Membrane Fusion by Munc18c In Vitro. PLoS ONE 3:12, pages e4074.
Crossref
Crossref
Jenna L. Jewell, Eunjin Oh, Sara M. Bennett, Samy O. Meroueh & Debbie C. Thurmond. (2008) The Tyrosine Phosphorylation of Munc18c Induces a Switch in Binding Specificity from Syntaxin 4 to Doc2β. Journal of Biological Chemistry 283:31, pages 21734-21746.
Crossref
Crossref
Wei Tian, Cong Ma, Yingfang Liu & Tao Xu. (2008) An efficient co-expression and purification system for the complex of Stx4 and C-terminal domain of Synip. Biochemical and Biophysical Research Communications 371:3, pages 366-370.
Crossref
Crossref
Margaret E. GrahamMark T. W. HandleyJeff W. BarclayLeo F. CiufoStephanie L. BarrowAlan MorganRobert D. Burgoyne. (2007) A gain-of-function mutant of Munc18-1 stimulates secretory granule recruitment and exocytosis and reveals a direct interaction of Munc18-1 with Rab3. Biochemical Journal 409:2, pages 407-416.
Crossref
Crossref
Mitsuhiko Umahara, Shuichi Okada, Eijiro Yamada, Tsugumichi Saito, Kihachi Ohshima, Koshi Hashimoto, Masanobu Yamada, Hiroyuki Shimizu, Jeffrey E. Pessin & Masatomo Mori. (2008) Tyrosine Phosphorylation of Munc18c Regulates Platelet-Derived Growth Factor-Stimulated Glucose Transporter 4 Translocation in 3T3L1 Adipocytes. Endocrinology 149:1, pages 40-49.
Crossref
Crossref
Eunjin Oh, Charles J. Heise, Jessie M. English, Melanie H. Cobb & Debbie C. Thurmond. (2007) WNK1 Is a Novel Regulator of Munc18c-Syntaxin 4 Complex Formation in Soluble NSF Attachment Protein Receptor (SNARE)-mediated Vesicle Exocytosis. Journal of Biological Chemistry 282:45, pages 32613-32622.
Crossref
Crossref
Ban Ke, Eunjin Oh & Debbie C. Thurmond. (2007) Doc2β Is a Novel Munc18c-interacting Partner and Positive Effector of Syntaxin 4-mediated Exocytosis. Journal of Biological Chemistry 282:30, pages 21786-21797.
Crossref
Crossref
Shu-Hong Hu, Catherine F. Latham, Christine L. Gee, David E. James & Jennifer L. Martin. (2007) Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteins. Proceedings of the National Academy of Sciences 104:21, pages 8773-8778.
Crossref
Crossref
Debbie C. Thurmond. 2007. Mechanisms of Insulin Action. Mechanisms of Insulin Action
52
70
.
Eva Gonzalez & Timothy E. McGraw. (2006) Insulin Signaling Diverges into Akt-dependent and -independent Signals to Regulate the Recruitment/Docking and the Fusion of GLUT4 Vesicles to the Plasma Membrane. Molecular Biology of the Cell 17:10, pages 4484-4493.
Crossref
Crossref
Eunjin Oh & Debbie C. Thurmond. (2006) The Stimulus-induced Tyrosine Phosphorylation of Munc18c Facilitates Vesicle Exocytosis. Journal of Biological Chemistry 281:26, pages 17624-17634.
Crossref
Crossref
Robert T. Watson & Jeffrey E. Pessin. (2006) Bridging the GAP between insulin signaling and GLUT4 translocation. Trends in Biochemical Sciences 31:4, pages 215-222.
Crossref
Crossref
Beth A. Spurlin & Debbie C. Thurmond. (2006) Syntaxin 4 Facilitates Biphasic Glucose-Stimulated Insulin Secretion from Pancreatic β-Cells. Molecular Endocrinology 20:1, pages 183-193.
Crossref
Crossref
Isabel R. Schlaepfer, Leslie K. Pulawa & Robert H. Eckel. (2005) Cloning and characterization of Munc18c(L), a novel murine Munc18c gene paralog. Biochemical and Biophysical Research Communications 334:3, pages 911-916.
Crossref
Crossref
Eunjin Oh, Beth A. Spurlin, Jeffrey E. Pessin & Debbie C. Thurmond. (2005) Munc18c Heterozygous Knockout Mice Display Increased Susceptibility for Severe Glucose Intolerance. Diabetes 54:3, pages 638-647.
Crossref
Crossref
Hajime Kanda, Yoshikazu Tamori, Hiroaki Shinoda, Mari Yoshikawa, Motoyoshi Sakaue, Jun Udagawa, Hiroki Otani, Fumi Tashiro, Jun-ichi Miyazaki & Masato Kasuga. (2005) Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. Journal of Clinical Investigation 115:2, pages 291-301.
Crossref
Crossref
Antonio Zorzano. 2005. The Metabolic Syndrome at the Beginning of the XXI Century. The Metabolic Syndrome at the Beginning of the XXI Century
15
42
.
Brenton L. Scott, Jeffrey S. Van Komen, Hassan Irshad, Song Liu, Kirilee A. Wilson & James A. McNew. (2004) Sec1p directly stimulates SNARE-mediated membrane fusion in vitro. The Journal of Cell Biology 167:1, pages 75-85.
Crossref
Crossref
Beth A. Spurlin, So-Young Park, Angela K. Nevins, Jason K. Kim & Debbie C. Thurmond. (2004) Syntaxin 4 Transgenic Mice Exhibit Enhanced Insulin-Mediated Glucose Uptake in Skeletal Muscle. Diabetes 53:9, pages 2223-2231.
Crossref
Crossref
Louise Chang, Shian-Huey Chiang & Alan R Saltiel. (2005) Insulin Signaling and the Regulation of Glucose Transport. Molecular Medicine 10:7-12, pages 65-71.
Crossref
Crossref
Takahiro Nakayama, Katsuhiko Mikoshiba, Tetsuo Yamamori & Kimio Akagawa. (2004) Activation of Syntaxin 1C, an Alternative Splice Variant of HPC-1/Syntaxin 1A, by Phorbol 12-Myristate 13-Acetate (PMA) Suppresses Glucose Transport into Astroglioma Cells via the Glucose Transporter-1 (GLUT-1). Journal of Biological Chemistry 279:22, pages 23728-23739.
Crossref
Crossref
Eugenia Carvalho, Sarah E. Schellhorn, Janice M. Zabolotny, Sally Martin, Effie Tozzo, Odile D. Peroni, Karen L. Houseknecht, Adrian Mundt, David E. James & Barbara B. Kahn. (2004) GLUT4 Overexpression or Deficiency in Adipocytes of Transgenic Mice Alters the Composition of GLUT4 Vesicles and the Subcellular Localization of GLUT4 and Insulin-responsive Aminopeptidase. Journal of Biological Chemistry 279:20, pages 21598-21605.
Crossref
Crossref
Robert T. Watson, Makoto Kanzaki & Jeffrey E. Pessin. (2004) Regulated Membrane Trafficking of the Insulin-Responsive Glucose Transporter 4 in Adipocytes. Endocrine Reviews 25:2, pages 177-204.
Crossref
Crossref
Shu-Hong Hu, Christine L Gee, Catherine F Latham, Scott W Rowlinson, Ulrika Rova, Alun Jones, Judy A Halliday, Nia J Bryant, David E James & Jennifer L Martin. (2003) Recombinant expression of Munc18c in a baculovirus system and interaction with syntaxin4. Protein Expression and Purification 31:2, pages 305-310.
Crossref
Crossref
Charlotte H. Widberg, Nia J. Bryant, Milena Girotti, Shane Rea & David E. James. (2003) Tomosyn Interacts with the t-SNAREs Syntaxin4 and SNAP23 and Plays a Role in Insulin-stimulated GLUT4 Translocation. Journal of Biological Chemistry 278:37, pages 35093-35101.
Crossref
Crossref
Beth A. Spurlin, Rhonda M. Thomas, Angela K. Nevins, Hyo-Jeong Kim, Yoon-Jung Kim, Hye-Lim Noh, Gerald I. Shulman, Jason K. Kim & Debbie C. Thurmond. (2003) Insulin Resistance in Tetracycline-Repressible Munc18c Transgenic Mice. Diabetes 52:8, pages 1910-1917.
Crossref
Crossref
Isabel R. Schlaepfer, Leslie K. Pulawa, Luis D.M. C-B. Ferreira, David E. James, Warren H. Capell & Robert H. Eckel. (2003) Increased expression of the SNARE accessory protein Munc18c in lipid-mediated insulin resistance. Journal of Lipid Research 44:6, pages 1174-1181.
Crossref
Crossref
Michael R. Logan, Solomon O. Odemuyiwa & Redwan Moqbel. (2003) Understanding exocytosis in immune and inflammatory cells: The molecular basis of mediator secretion. Journal of Allergy and Clinical Immunology 111:5, pages 923-932.
Crossref
Crossref
Naira Gorovits & Maureen J. Charron. (2003) What we know about facilitative glucose transporters: Lessons from cultured cells, animal models, and human studies. Biochemistry and Molecular Biology Education 31:3, pages 163-172.
Crossref
Crossref
Ruud F.G. Toonen & Matthijs Verhage. (2003) Vesicle trafficking: pleasure and pain from SM genes. Trends in Cell Biology 13:4, pages 177-186.
Crossref
Crossref
Guoli Chen, Ping Liu, Debbie C. Thurmond & Jeffrey S. Elmendorf. (2003) Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c. FEBS Letters 534:1-3, pages 54-60.
Crossref
Crossref
Sophie Martin-Verdeaux, Isabel Pombo, Bruno Iannascoli, Michèle Roa, Nadine Varin-Blank, Juan Rivera & Ulrich Blank. (2003) Evidence of a role for Munc18-2 and microtubules in mast cell granule exocytosis. Journal of Cell Science 116:2, pages 325-334.
Crossref
Crossref
S.Lance Macaulay, Julian Grusovin, Violet Stoichevska, Joanne M Ryan, Laura A Castelli & Colin W Ward. (2002) Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells. FEBS Letters 528:1-3, pages 154-160.
Crossref
Crossref
Silvia Mora & Jeffrey E. Pessin. (2002) An adipocentric view of signaling and intracellular trafficking. Diabetes/Metabolism Research and Reviews 18:5, pages 345-356.
Crossref
Crossref
Makoto Kanzaki & Jeffrey E. Pessin. (2002) Caveolin-associated Filamentous Actin (Cav-actin) Defines a Novel F-actin Structure in Adipocytes. Journal of Biological Chemistry 277:29, pages 25867-25869.
Crossref
Crossref
Jiwon Ryu, Jong Sik Hah, James S.S Park, Wan Lee, Amrit L Rampal & Chan Y Jung. (2002) Protein kinase C-ζ phosphorylates insulin-responsive aminopeptidase in vitro at Ser-80 and Ser-91. Archives of Biochemistry and Biophysics 403:1, pages 71-82.
Crossref
Crossref
Shian-Huey Chiang, June Chunqiu Hou, Joseph Hwang, Jeffrey E. Pessin & Alan R. Saltiel. (2002) Cloning and Functional Characterization of Related TC10 Isoforms, a Subfamily of Rho Proteins Involved in Insulin-stimulated Glucose Transport. Journal of Biological Chemistry 277:15, pages 13067-13073.
Crossref
Crossref
Bryce A. Nelson, Katherine A. Robinson & Maria G. Buse. (2002) Insulin Acutely Regulates Munc18-c Subcellular Trafficking. Journal of Biological Chemistry 277:6, pages 3809-3812.
Crossref
Crossref
Patricia IozzoThonchai PratipanawatrHanno PijlChristoph VogtVineeta KumarRuben PipekMasafumi MatsudaLawrence J. Mandarino, Kenneth J. CusiRalph A. DeFronzo. (2001) Physiological hyperinsulinemia impairs insulin-stimulated glycogen synthase activity and glycogen synthesis. American Journal of Physiology-Endocrinology and Metabolism 280:5, pages E712-E719.
Crossref
Crossref
Shian-Huey Chiang, Christian A. Baumann, Makoto Kanzaki, Debbie C. Thurmond, Robert T. Watson, Cheryl L. Neudauer, Ian G. Macara, Jeffrey E. Pessin & Alan R. Saltiel. (2001) Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature 410:6831, pages 944-948.
Crossref
Crossref
Debbie C. Thurmond & Jeffrey E. Pessin. (2001) Molecular basis for insulin-stimulated GLUT4 translocation. Current Opinion in Endocrinology & Diabetes 8:2, pages 67-73.
Crossref
Crossref
Ann Louise Olson, Alan R. Trumbly & George V. Gibson. (2001) Insulin-mediated GLUT4 Translocation Is Dependent on the Microtubule Network. Journal of Biological Chemistry 276:14, pages 10706-10714.
Crossref
Crossref
Christian A. Baumann & Alan R. Saltiel. (2001) Spatial compartmentalization of signal transduction in insulin action. BioEssays 23:3, pages 215-222.
Crossref
Crossref
Ahmir H. Khan, Debbie C. Thurmond, Chunmei Yang, Brian P. Ceresa, Curt D. Sigmund & Jeffrey E. Pessin. (2001) Munc18c Regulates Insulin-stimulated GLUT4 Translocation to the Transverse Tubules in Skeletal Muscle. Journal of Biological Chemistry 276:6, pages 4063-4069.
Crossref
Crossref
Fiona Simpson, Jonathan P. Whitehead & David E. James. (2001) GLUT4 - At the Cross Roads Between Membrane Trafficking and Signal Transduction. Traffic 2:1, pages 2-11.
Crossref
Crossref
Leonard J. Foster & Amira Klip. (2000) Mechanism and regulation of GLUT-4 vesicle fusion in muscle and fat cells. American Journal of Physiology-Cell Physiology 279:4, pages C877-C890.
Crossref
Crossref
Debbie C. Thurmond & Jeffrey E. Pessin. (2000) Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant. The EMBO Journal 19:14, pages 3565-3575.
Crossref
Crossref
Leonard J. Foster, M. Lynn Weir, Dawn Y. Lim, Zhi Liu, William S. Trimble & Amira Klip. (2000) A Functional Role for VAP-33 in Insulin-Stimulated GLUT4 Traffic. Traffic 1:6, pages 512-521.
Crossref
Crossref