Munc18c Function Is Required for Insulin-Stimulated Plasma Membrane Fusion of GLUT4 and Insulin-Responsive Amino Peptidase Storage Vesicles

REFERENCES

• Cao, X., Ballew, N., and Barlowe, C.. 1998. Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins. EMBO J. 17:2156–2165
   PubMedGoogle Scholar
• Cheatham, B., Volchuk, A., Kahn, C. R., Wang, L., Rhodes, C. J., and Klip, A.. 1996. Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins. Proc. Natl. Acad. Sci. USA 93:15169–15173
   PubMedGoogle Scholar
• Czech, M. P.. 1995. Molecular actions of insulin on glucose transport. Annu. Rev. Nutr. 15:441–471
   PubMed Web of Science ®Google Scholar
• Dascher, C., Ossig, R., Gallwitz, D., and Schmitt, H. D.. 1991. Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily. Mol. Cell. Biol. 11:872–885
   PubMedGoogle Scholar
• Dresbach, T., Burns, M. E., O'Connor, V., De Bello, W. M., and Betz, W. M.. 1998. A neuronal Sec1 homolog regulates neurotransmitter release at the squid giant synapse. J. Neurosci. 18:2923–2932
   PubMedGoogle Scholar
• Elmendorf, J. S., Chen, D., and Pessin, J. E.. 1998. Guanosine 5′-O-(3-thiotriphosphate) (GTPγS) stimulation of GLUT4 translocation is tyrosine kinase-dependent. J. Biol. Chem. 273:13289–13296
   PubMedGoogle Scholar
• Fletcher, A. I., Shuang, R., Giovannucci, D. R., Zhang, L., Bittner, M. A., and Stuenkel, E. L.. 1999. Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18. J. Biol. Chem. 274:4027–4035
   PubMed Web of Science ®Google Scholar
• Fujita, H., Tuma, P. L., Finnegan, C. M., Locco, L., and Hubbard, A. L.. 1998. Endogenous syntaxins 2, 3 and 4 exhibit distinct but overlapping patterns of expression at the hepatocyte plasma membrane. Biochem. J. 329:527–538
   PubMedGoogle Scholar
• Fujita, Y., Sasaki, T., Fukui, K., Kotani, H., Kimura, T., Hata, Y., Sudhof, T. C., Scheller, R. H., and Takai, Y.. 1996. Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin. J. Biol. Chem. 271:7265–7268
   PubMedGoogle Scholar
• Harrison, S. D., Broadie, K., van de Goor, J., and Rubin, G. M.. 1994. Mutations in the Drosophila Rop gene suggest a function in general secretion and synaptic transmission. Neuron 13:555–566
   PubMedGoogle Scholar
• Hata, Y., and Sudhof, T. C.. 1995. A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. J. Biol. Chem. 270:13022–13028
   PubMed Web of Science ®Google Scholar
• Hirling, H., and Scheller, R. H.. 1996. Phosphorylation of synaptic vesicle proteins: modulation of the alpha SNAP interaction with the core complex. Proc. Natl. Acad. Sci. USA 93:11945–11949
   PubMedGoogle Scholar
• Hosono, R., Hekimi, S., Kamiya, Y., Sassa, T., Murakami, S., Nishiwaki, K., Miwa, J., Taketo, A., and Kodaira, K. I.. 1992. The unc-18 gene encodes a novel protein affecting the kinetics of acetylcholine metabolism in the nematode Caenorhabditis elegans. J. Neurochem. 58:1517–1525
   PubMedGoogle Scholar
• Kandror, K. V., and Pilch, P. F.. 1996. Compartmentalization of protein traffic in insulin-sensitive cells. Am. J. Physiol. 271:E1–E14
   PubMed Web of Science ®Google Scholar
• Kandror, K. V., and Pilch, P. F.. 1994. gp160, a tissue-specific marker for insulin-activated glucose transport. Proc. Natl. Acad. Sci. USA 91:8017–8021
   PubMedGoogle Scholar
• Kandror, K. V., Yu, L., and Pilch, P. F.. 1994. The major protein of GLUT4-containing vesicles, gp160, has aminopeptidase activity. J. Biol. Chem. 269:30777–30780
   PubMedGoogle Scholar
• Lupashin, V. V., and Waters, M. G.. 1997. t-SNARE activation through transient interaction with a rab-like guanosine triphosphatase. Science 276:1255–1258
   PubMedGoogle Scholar
• Malide, D., St-Denis, J. F., Keller, S. R., and Cushman, S. W.. 1997. Vp165 and GLUT4 share similar vesicle pools along their trafficking pathways in rat adipose cells. FEBS Lett. 409:461–468
   PubMedGoogle Scholar
• Martin, L. B., Shewan, A., Millar, C. A., Gould, G. W., and James, D. E.. 1998. Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes. J. Biol. Chem. 273:1444–1452
   PubMedGoogle Scholar
• Martin, S., Rice, J. E., Gould, G. W., Keller, S. R., Slot, J. W., and James, D. E.. 1997. The glucose transporter GLUT4 and the aminopeptidase vp165 colocalise in tubulo-vesicular elements in adipocytes and cardiomyocytes. J. Cell Sci. 110:2281–2291
   PubMedGoogle Scholar
• Novick, P., and Schekman, R.. 1979. Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 76:1858–1862
   PubMed Web of Science ®Google Scholar
• Okamoto, M., and Sudhof, T. C.. 1997. Mints, Munc18-interacting proteins in synaptic vesicle exocytosis. J. Biol. Chem. 272:31459–31464
   PubMed Web of Science ®Google Scholar
• Olson, A. L., Knight, J. B., and Pessin, J. E.. 1997. Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes. Mol. Cell. Biol. 17:2425–2435
   PubMed Web of Science ®Google Scholar
• Olson, A. L., and Pessin, J. E.. 1996. Structure, function, and regulation of the mammalian facilitative glucose transporter gene family. Annu. Rev. Nutr. 16:235–256
   PubMed Web of Science ®Google Scholar
• Pessin, J. E., Thurmond, D. C., Elmendorf, J. S., Coker, K. J., and Okada, S.. 1999. Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location! J. Biol. Chem. 274:2593–2596
   PubMed Web of Science ®Google Scholar
• Pevsner, J., Hsu, S. C., Braun, J. E., Calakos, N., Ting, A. E., Bennett, M. K., and Scheller, R. H.. 1994. Specificity and regulation of a synaptic vesicle docking complex. Neuron 13:353–361
   PubMedGoogle Scholar
• Rea, S., and James, D. E.. 1997. Moving GLUT4. The biogenesis and trafficking of GLUT4 storage vesicles. Diabetes 46:1667–1677
   PubMed Web of Science ®Google Scholar
• Ross, S. A., Scott, H. M., Morris, N. J., Leung, W. Y., Mao, F., Lienhard, G. E., and Keller, S. R.. 1996. Characterization of the insulin-regulated membrane aminopeptidase in 3T3-L1 adipocytes. J. Biol. Chem. 271:3328–3332
   PubMedGoogle Scholar
• Schulze, K. L., Littleton, J. T., Salzberg, A., Halachmi, N., Stern, M., Lev, Z., and Bellen, H. J.. 1994. rop, a Drosophila homolog of yeast Sec1 and vertebrate n-Sec1/Munc-18 proteins, is a negative regulator of neurotransmitter release in vivo. Neuron 13:1099–1108
   PubMedGoogle Scholar
• Slot, J. W., Geuze, H. J., Gigengack, S., James, D. E., and Lienhard, G. E.. 1991. Translocation of the glucose transporter GLUT4 in cardiac myocytes of the rat. Proc. Natl. Acad. Sci. USA 88:7815–7819
   PubMed Web of Science ®Google Scholar
• Slot, J. W., Geuze, H. J., Gigengack, S., Lienhard, G. E., and James, D. E.. 1991. Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat. J. Cell Biol. 113:123–135
   PubMed Web of Science ®Google Scholar
• Tamori, Y., Kawanishi, M., Niki, T., Shinoda, H., Araki, S., Okazawa, H., and Kasuga, M.. 1998. Inhibition of insulin-induced GLUT4 translocation by Munc18c through interaction with syntaxin 4 in 3T3-L1 adipocytes. J. Biol. Chem. 273:19740–19746
   PubMedGoogle Scholar
• Tellam, J. T., Macaulay, S. L., McIntosh, S., Hewish, D. R., Ward, C. W., and James, D. E.. 1997. Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. J. Biol. Chem. 272:6179–6186
   PubMedGoogle Scholar
• Thurmond, D. C., Ceresa, B. P., Okada, S., Elmendorf, J. S., Coker, K., and Pessin, J. E.. 1998. Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes. J. Biol. Chem. 273:33876–33883
   PubMedGoogle Scholar
• Van Rheenen, S. M., Cao, X., Lupashin, V. V., Barlowe, C., and Waters, M. G.. 1998. Sec35p, a novel peripheral membrane protein, is required for ER to golgi vesicle docking. J. Cell Biol. 141:1107–1119
   PubMedGoogle Scholar
• Verhage, M., de Vries, K. J., Roshol, H., Burbach, J. P., Gispen, W. H., and Sudhof, T. C.. 1997. DOC2 proteins in rat brain: complementary distribution and proposed function as vesicular adapter proteins in early stages of secretion. Neuron 18:453–461
   PubMedGoogle Scholar
• Volchuk, A., Wang, Q., Ewart, H. S., Liu, Z., He, L., Bennett, M. K., and Klip, A.. 1996. Syntaxin 4 in 3T3-L1 adipocytes: regulation by insulin and participation in insulin-dependent glucose transport. Mol. Biol. Cell. 7:1075–1082
   PubMedGoogle Scholar