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Molecular and Cellular Biology Volume 20, 2000 - Issue 11
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DNA Dynamics and Chromosome Structure

Conversion of Topoisomerase I Cleavage Complexes on the Leading Strand of Ribosomal DNA into 5′-Phosphorylated DNA Double-Strand Breaks by Replication Runoff

Dirk Strumberg1 Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland20892-4255
,
André A. Pilon1 Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland20892-4255
,
Melanie Smith2 Department of Pharmacology and Experimental Therapeutics, University of Maryland, Baltimore, Maryland21201
,
Robert Hickey2 Department of Pharmacology and Experimental Therapeutics, University of Maryland, Baltimore, Maryland21201
,
Linda Malkas2 Department of Pharmacology and Experimental Therapeutics, University of Maryland, Baltimore, Maryland21201
&
Yves Pommier1 Laboratory of Molecular Pharmacology, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland20892-4255Correspondence[email protected]
Pages 3977-3987 | Received 16 Nov 1999, Accepted 03 Mar 2000, Published online: 28 Mar 2023

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