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Transcriptional Regulation

Discrete Roles for Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor in Recruiting Nuclear Receptor Coactivators

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Pages 8008-8017 | Received 02 May 2000, Accepted 31 Jul 2000, Published online: 28 Mar 2023

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Giuseppina Barrera, Cristina Toaldo, Stefania Pizzimenti, Angelo Cerbone, Piergiorgio Pettazzoni, Mario Umberto Dianzani & Carlo Ferretti. (2008) The Role of PPAR Ligands in Controlling Growth-Related Gene Expression and their Interaction with Lipoperoxidation Products. PPAR Research 2008, pages 1-15.
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Masahito Shimizu & Hisataka Moriwaki. (2008) Synergistic Effects of PPAR Ligands and Retinoids in Cancer Treatment . PPAR Research 2008, pages 1-10.
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W. Wu, J. Celestino, M. R. Milam, K. M. Schmeler, R. R. Broaddus, L. H. Ellenson & K. H. Lu. (2008) Primary chemoprevention of endometrial hyperplasia with the peroxisome proliferator-activated receptor gamma agonist rosiglitazone in the PTEN heterozygote murine model . International Journal of Gynecologic Cancer 18:2, pages 329-338.
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W. Ahmed, O. Ziouzenkova, J. Brown, P. Devchand, S. Francis, M. Kadakia, T. Kanda, G. Orasanu, M. Sharlach, F. Zandbergen & J. Plutzky. (2007) PPARs and their metabolic modulation: new mechanisms for transcriptional regulation?. Journal of Internal Medicine 262:2, pages 184-198.
Crossref
Mary M. McGrane. (2007) Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. The Journal of Nutritional Biochemistry 18:8, pages 497-508.
Crossref
Fu-Sheng Chou, Pei-Shan Wang, Samuel Kulp & Joseph J. Pinzone. (2007) Effects of Thiazolidinediones on Differentiation, Proliferation, and Apoptosis. Molecular Cancer Research 5:6, pages 523-530.
Crossref
Andreas von Knethen, Mathias Soller, Nico Tzieply, Andreas Weigert, Axel M. Johann, Carla Jennewein, Roman Köhl & Bernhard Brüne. (2007) PPARγ1 attenuates cytosol to membrane translocation of PKCα to desensitize monocytes/macrophages. Journal of Cell Biology 176:5, pages 681-694.
Crossref
Michael C. Schuster, Hui Chen & John D. Lambris. 2007. Current Topics in Innate Immunity. Current Topics in Innate Immunity 407 417 .
GYESIK MIN. (2006) Different Modulation of ER-Mediated Transactivation by Xenobiotic Nuclear Receptors Depending on the Estrogen Response Elements and Estrogen Target Cell Types. Annals of the New York Academy of Sciences 1091:1, pages 244-257.
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Liliane Michalik, Johan Auwerx, Joel P. Berger, V. Krishna Chatterjee, Christopher K. Glass, Frank J. Gonzalez, Paul A. Grimaldi, Takashi Kadowaki, Mitchell A. Lazar, Stephen O'Rahilly, Colin N. A. Palmer, Jorge Plutzky, Janardan K. Reddy, Bruce M. Spiegelman, Bart Staels & Walter Wahli. (2006) International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors. Pharmacological Reviews 58:4, pages 726-741.
Crossref
Yoshitomo Hamuro, Stephen J. Coales, Jeffrey A. Morrow, Kathleen S. Molnar, Steven J. Tuske, Mark R. Southern & Patrick R. Griffin. (2006) Hydrogen/deuterium-exchange (H/D-Ex) of PPARγ LBD in the presence of various modulators. Protein Science 15:8, pages 1883-1892.
Crossref
Eung Jae Yoo, Jun-Jae Chung, Sung Sik Choe, Kang Ho Kim & Jae Bum Kim. (2006) Down-regulation of Histone Deacetylases Stimulates Adipocyte Differentiation. Journal of Biological Chemistry 281:10, pages 6608-6615.
Crossref
Jérôme N. Feige, Laurent Gelman, Liliane Michalik, Béatrice Desvergne & Walter Wahli. (2006) From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Progress in Lipid Research 45:2, pages 120-159.
Crossref
M. Belakavadi & J. D. Fondell. 2006. Reviews of Physiology, Biochemistry and Pharmacology. Reviews of Physiology, Biochemistry and Pharmacology 23 43 .
Adrian T. Coyle, Martina B. O'Keeffe & B. Therese Kinsella. (2005) 15-Deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells. FEBS Journal 272:18, pages 4754-4773.
Crossref
A. Hammarstedt, C.X. Andersson, V. Rotter Sopasakis & U. Smith. (2005) The effect of PPARγ ligands on the adipose tissue in insulin resistance. Prostaglandins, Leukotrienes and Essential Fatty Acids 73:1, pages 65-75.
Crossref
Shuichi Fukuen, Masanori Iwaki, Atsutaka Yasui, Makoto Makishima, Morihiro Matsuda & Iichiro Shimomura. (2005) Sulfonylurea Agents Exhibit Peroxisome Proliferator-activated Receptor γ Agonistic Activity. Journal of Biological Chemistry 280:25, pages 23653-23659.
Crossref
Maureen A. Murtaugh, Khe-ni Ma, Bette J. Caan, Carol Sweeney, Roger Wolff, Wade S. Samowitz, John D. Potter & Martha L. Slattery. (2005) Interactions of Peroxisome Proliferator–Activated Receptor γ and Diet in Etiology of Colorectal Cancer. Cancer Epidemiology, Biomarkers & Prevention 14:5, pages 1224-1229.
Crossref
Kendall W. NettlesGeoffrey L. Greene. (2005) LIGAND CONTROL OF COREGULATOR RECRUITMENT TO NUCLEAR RECEPTORS. Annual Review of Physiology 67:1, pages 309-333.
Crossref
Nguan Soon Tan, Liliane Michalik, Beatrice Desvergne & Walter Wahli. (2005) Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes. The Journal of Steroid Biochemistry and Molecular Biology 93:2-5, pages 99-105.
Crossref
Tsuyoshi Monden, Masanobu Yamada, Yasuyo Nihei, Mikiko Kishi, Takuya Tomaru, Sumiyasu Ishii, Tetsu Hashida, Nobuyuki Shibusawa, Koshi Hashimoto, Teturou Satoh, Kikuo Kasai & Masatomo Mori. (2004) Unliganded RXR acts as an inhibitory factor on troglitazone-induced activation. Life Sciences 76:7, pages 731-741.
Crossref
David L Crowe & Roshantha AS Chandraratna. (2004) A retinoid X receptor (RXR)-selective retinoid reveals that RXR-α is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands. Breast Cancer Research 6:5.
Crossref
Marina Konopleva, Elena Elstner, Teresa J. McQueen, Twee Tsao, Andrey Sudarikov, Wei Hu, Wendy D. Schober, Rui-Yu Wang, David Chism, Steven M. Kornblau, Anas Younes, Steven J. Collins, H. Phillip Koeffler & Michael Andreeff. (2004) Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias. Molecular Cancer Therapeutics 3:10, pages 1249-1262.
Crossref
Inés Pineda Torra, Leonard P. Freedman & Michael J. Garabedian. (2004) Identification of DRIP205 as a Coactivator for the Farnesoid X Receptor. Journal of Biological Chemistry 279:35, pages 36184-36191.
Crossref
Chandan Sharma, Anamika Pradeep, Lucas Wong, Ajay Rana & Basabi Rana. (2004) Peroxisome Proliferator-activated Receptor γ Activation Can Regulate β-Catenin Levels via a Proteasome-mediated and Adenomatous Polyposis Coli-independent Pathway. Journal of Biological Chemistry 279:34, pages 35583-35594.
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Annemieke IJpenberg, Nguan Soon Tan, Laurent Gelman, Sander Kersten, Josiane Seydoux, Jianming Xu, Daniel Metzger, Laurence Canaple, Pierre Chambon, Walter Wahli & Béatrice Desvergne. (2004) In vivo activation of PPAR target genes by RXR homodimers. The EMBO Journal 23:10, pages 2083-2091.
Crossref
Chandan Sharma, Anamika Pradeep, Richard G. Pestell & Basabi Rana. (2004) Peroxisome Proliferator-activated Receptor γ Activation Modulates Cyclin D1 Transcription via β-Catenin-independent and cAMP-response Element-binding Protein-dependent Pathways in Mouse Hepatocytes. Journal of Biological Chemistry 279:17, pages 16927-16938.
Crossref
Martin L. Privalsky. (2004) The Role of Corepressors in Transcriptional Regulation by Nuclear Hormone Receptors. Annual Review of Physiology 66:1, pages 315-360.
Crossref
Mari Luz Acevedo, Kathleen C Lee, Joshua D Stender, Benita S Katzenellenbogen & W.Lee Kraus. (2004) Selective Recognition of Distinct Classes of Coactivators by a Ligand-Inducible Activation Domain. Molecular Cell 13:5, pages 725-738.
Crossref
Julia A. Lawrence & Kapil Dhingra. 2004. Cancer Chemoprevention. Cancer Chemoprevention 195 208 .
Christian Landles, Sara Chalk, Jennifer H. Steel, Ian Rosewell, Bradley Spencer-Dene, El-Nasir Lalani & Malcolm G. Parker. (2003) The Thyroid Hormone Receptor-Associated Protein TRAP220 Is Required at Distinct Embryonic Stages in Placental, Cardiac, and Hepatic Development. Molecular Endocrinology 17:12, pages 2418-2435.
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Perkins Mukunyadzi, Lingbao Ai, Didier Portilla, E Leon Barnes & Chun-Yang Fan. (2003) Expression of Peroxisome Proliferator–Activated Receptor Gamma in Salivary Duct Carcinoma: Immunohistochemical Analysis of 15 Cases. Modern Pathology 16:12, pages 1218-1223.
Crossref
David J. Bettoun, Thomas P. Burris, Keith A. Houck, Donald W. BuckIIII, Keith R. Stayrook, Berket Khalifa, Jianfen Lu, William W. Chin & Sunil Nagpal. (2003) Retinoid X Receptor Is a Nonsilent Major Contributor to Vitamin D Receptor-Mediated Transcriptional Activation. Molecular Endocrinology 17:11, pages 2320-2328.
Crossref
Annika E Wallberg, Soichiro Yamamura, Sohail Malik, Bruce M Spiegelman & Robert G Roeder. (2003) Coordination of p300-Mediated Chromatin Remodeling and TRAP/Mediator Function through Coactivator PGC-1α. Molecular Cell 12:5, pages 1137-1149.
Crossref
Xiaotao Li & Bert W. O'Malley. (2003) Unfolding the Action of Progesterone Receptors. Journal of Biological Chemistry 278:41, pages 39261-39264.
Crossref
Jilin Liu, Hui Li, Sumner H. Burstein, Robert B. Zurier & J. Don Chen. (2003) Activation and Binding of Peroxisome Proliferator-Activated Receptor γ by Synthetic Cannabinoid Ajulemic Acid. Molecular Pharmacology 63:5, pages 983-992.
Crossref
Li-Na Wei. (2003) Retinoid Receptors and Their Coregulators. Annual Review of Pharmacology and Toxicology 43:1, pages 47-72.
Crossref
Cécile Rochette-Egly. (2003) Nuclear receptors: integration of multiple signalling pathways through phosphorylation. Cellular Signalling 15:4, pages 355-366.
Crossref
Lawrence J. Saubermann, Atsushi Nakajima, Koichiro Wada, Shuping Zhao, Yasuo Terauchi, Takashi Kadowaki, Hiroyuki Aburatani, Nobuyuki Matsuhashi, Ryozo Nagai & Richard S. Blumberg. (2002) Peroxisome Proliferator-Activated Receptor Gamma Agonist Ligands Stimulate a Th2 Cytokine Response and Prevent Acute Colitis. Inflammatory Bowel Diseases 8:5, pages 330-339.
Crossref
B A Stoll. (2002) Linkage between retinoid and fatty acid receptors: implications for breast cancer prevention. European Journal of Cancer Prevention 11:4, pages 319-325.
Crossref
Marina Konopleva & Michael Andreeff. (2002) Role of peroxisome proliferator-activated receptor-γ in hematologic malignancies. Current Opinion in Hematology 9:4, pages 294-302.
Crossref
Beata Lecka-Czernik, Elena J. Moerman, David F. Grant, Jürgen M. Lehmann, Stavros C. Manolagas & Robert L. Jilka. (2002) Divergent Effects of Selective Peroxisome Proliferator-Activated Receptor-γ2 Ligands on Adipocyte Versus Osteoblast Differentiation. Endocrinology 143:6, pages 2376-2384.
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CLAUS JØRGENSEN, ANNE-M. KROGSDAM, IRINA KRATCHMAROVA, TIMOTHY M. WILLSON, JENS KNUDSEN, SUSANNE MANDRUP & KARSTEN KRISTIANSEN. (2006) Opposing Effects of Fatty Acids and Acyl-CoA Esters on Conformation and Cofactor Recruitment of Peroxisome Proliferator-Activated Receptors. Annals of the New York Academy of Sciences 967:1, pages 431-439.
Crossref
Philippe Delerive, Karolien De Bosscher, Wim Vanden Berghe, Jean-Charles Fruchart, Guy Haegeman & Bart Staels. (2002) DNA Binding-Independent Induction of IκBα Gene Transcription by PPARα. Molecular Endocrinology 16:5, pages 1029-1039.
Crossref
Yong Li & Mitchell A. Lazar. (2002) Differential Gene Regulation by PPARγ Agonist and Constitutively Active PPARγ2. Molecular Endocrinology 16:5, pages 1040-1048.
Crossref
Gary Lee, Fabienne Elwood, John McNally, Jennifer Weiszmann, Michelle Lindstrom, Kate Amaral, Motonao Nakamura, Shichang Miao, Ping Cao, R. Marc Learned, Jin-Long Chen & Yang Li. (2002) T0070907, a Selective Ligand for Peroxisome Proliferator-activated Receptor γ, Functions as an Antagonist of Biochemical and Cellular Activities. Journal of Biological Chemistry 277:22, pages 19649-19657.
Crossref
Kai Ge, Mohamed Guermah, Chao-Xing Yuan, Mitsuhiro Ito, Annika E. Wallberg, Bruce M. Spiegelman & Robert G. Roeder. (2002) Transcription coactivator TRAP220 is required for PPARγ2-stimulated adipogenesis. Nature 417:6888, pages 563-567.
Crossref
Ciaran P. Sewter, Fiona Blows, Antonio Vidal-Puig & Stephen O’Rahilly. (2002) Regional Differences in the Response of Human Pre-Adipocytes to PPARγ and RXRα Agonists. Diabetes 51:3, pages 718-723.
Crossref
H. Eric Xu, Thomas B. Stanley, Valerie G. Montana, Millard H. Lambert, Barry G. Shearer, Jeffery E. Cobb, David D. McKee, Cristin M. Galardi, Kelli D. Plunket, Robert T. Nolte, Derek J. Parks, John T. Moore, Steven A. Kliewer, Timothy M. Willson & Julie B. Stimmel. (2002) Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα. Nature 415:6873, pages 813-817.
Crossref
Sven Schinner, Claudia Dellas, Margit Schröder, Cynthia A. Heinlein, Chawnshang Chang, Janina Fischer & Willhart Knepel. (2002) Repression of Glucagon Gene Transcription by Peroxisome Proliferator-activated Receptor γ through Inhibition of Pax6 Transcriptional Activity. Journal of Biological Chemistry 277:3, pages 1941-1948.
Crossref
Pierre Germain, Jaya Iyer, Christina Zechel & Hinrich Gronemeyer. (2002) Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. Nature 415:6868, pages 187-192.
Crossref
Michael B Sporn, Nanjoo Suh & David J Mangelsdorf. (2001) Prospects for prevention and treatment of cancer with selective PPARγ modulators (SPARMs). Trends in Molecular Medicine 7:9, pages 395-400.
Crossref
Jay O. Boyle. (2001) Retinoid mechanisms and cyclins. Current Oncology Reports 3:4, pages 301-305.
Crossref
Timothy M. WillsonMillard H. LambertSteven A. Kliewer. (2001) Peroxisome Proliferator–Activated Receptor γ and Metabolic Disease. Annual Review of Biochemistry 70:1, pages 341-367.
Crossref
Inés Pineda Torra, Giulia Chinetti, Caroline Duval, Jean-Charles Fruchart & Bart Staels. (2001) Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice. Current Opinion in Lipidology 12:3, pages 245-254.
Crossref
Anette Wärnmark, Tova Almlöf, Jörg Leers, Jan-Åke Gustafsson & Eckardt Treuter. (2001) Differential Recruitment of the Mammalian Mediator Subunit TRAP220 by Estrogen Receptors ERα and ERβ. Journal of Biological Chemistry 276:26, pages 23397-23404.
Crossref
Christophe Rachez & Leonard P Freedman. (2001) Mediator complexes and transcription. Current Opinion in Cell Biology 13:3, pages 274-280.
Crossref
F Jeffrey Dilworth & Pierre Chambon. (2001) Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription. Oncogene 20:24, pages 3047-3054.
Crossref

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