Molecular and Cellular Biology, Volume 20, Issue 21 (2000)

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Molecular and Cellular Biology, Volume 20, Issue 21 (2000)

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Minireviews

Article
Roles for Mismatch Repair Factors in Regulating Genetic Recombination
Elizabeth Evans & Eric Alani
Pages: 7839-7844
Published online: 28 Mar 2023
First Page PreviewforRoles for Mismatch Repair Factors in Regulating Genetic Recombination | Full Text | References | PDF (85.1 KB)
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Gene Expression

Article
The Abundance of Met30p Limits SCFMet30p Complex Activity and Is Regulated by Methionine Availability
Dechelle B. Smothers, Lukasz Kozubowski, Cheryl Dixon, Mark G. Goebl & Neal Mathias
Pages: 7845-7852
Published online: 28 Mar 2023
AbstractforThe Abundance of Met30p Limits SCFMet30p Complex Activity and Is Regulated by Methionine Availability | Full Text | References | PDF (1,003.2 KB)
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Article
Down-Regulation of Cyclin D1 Expression by Prostaglandin A2 Is Mediated by Enhanced Cyclin D1 mRNA Turnover
Shankung Lin, Wengong Wang, Gerald M. Wilson, Xiaoling Yang, Gary Brewer, Nikki J. Holbrook & Myriam Gorospe
Pages: 7903-7913
Published online: 28 Mar 2023
AbstractforDown-Regulation of Cyclin D1 Expression by Prostaglandin A2 Is Mediated by Enhanced Cyclin D1 mRNA Turnover | Full Text | References | PDF (2.2 MB)
  • 28 Views
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Article
mRNA Decapping in Yeast Requires Dissociation of the Cap Binding Protein, Eukaryotic Translation Initiation Factor 4E
David C. Schwartz & Roy Parker
Pages: 7933-7942
Published online: 28 Mar 2023
AbstractformRNA Decapping in Yeast Requires Dissociation of the Cap Binding Protein, Eukaryotic Translation Initiation Factor 4E | Full Text | References | PDF (1.3 MB)
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Article
Evidence for Splice Site Pairing via Intron Definition in Schizosaccharomyces pombe
Charles M. Romfo, Consuelo J. Alvarez, Willem J. van Heeckeren, Christopher J. Webb & Jo Ann Wise
Pages: 7955-7970
Published online: 28 Mar 2023
AbstractforEvidence for Splice Site Pairing via Intron Definition in Schizosaccharomyces pombe | Full Text | References | PDF (1.4 MB)
  • 31 Views
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Article
cis- and trans-Acting Determinants for Translation of psbD mRNA in Chlamydomonas reinhardtii
Friedrich Ossenbühl & Jörg Nickelsen
Pages: 8134-8142
Published online: 28 Mar 2023
Abstractforcis- and trans-Acting Determinants for Translation of psbD mRNA in Chlamydomonas reinhardtii | Full Text | References | PDF (3.1 MB)
  • 13 Views
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Article
Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes
Scott A. Jelinsky, Preston Estep, George M. Church & Leona D. Samson
Pages: 8157-8167
Published online: 28 Mar 2023
AbstractforRegulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes | Full Text | References | PDF (3.5 MB)
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Article
The CUL1 C-Terminal Sequence and ROC1 Are Required for Efficient Nuclear Accumulation, NEDD8 Modification, and Ubiquitin Ligase Activity of CUL1
Manabu Furukawa, Yanping Zhang, Joseph McCarville, Tomohiko Ohta & Yue Xiong
Pages: 8185-8197
Published online: 28 Mar 2023
AbstractforThe CUL1 C-Terminal Sequence and ROC1 Are Required for Efficient Nuclear Accumulation, NEDD8 Modification, and Ubiquitin Ligase Activity of CUL1 | Full Text | References | PDF (3.1 MB)
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Article
Arginine-Rich Regions Mediate the RNA Binding and Regulatory Activities of the Protein Encoded by the Drosophila melanogaster suppressor of sable Gene
Michael A. Turnage, Paul Brewer-Jensen, Wen-Li Bai & Lillie L. Searles
Pages: 8198-8208
Published online: 28 Mar 2023
AbstractforArginine-Rich Regions Mediate the RNA Binding and Regulatory Activities of the Protein Encoded by the Drosophila melanogaster suppressor of sable Gene | Full Text | References | PDF (1.5 MB)
  • 21 Views
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Article
Function of the Ski4p (Csl4p) and Ski7p Proteins in 3′-to-5′ Degradation of mRNA
Ambro van Hoof, Robin R. Staples, Richard E. Baker & Roy Parker
Pages: 8230-8243
Published online: 28 Mar 2023
AbstractforFunction of the Ski4p (Csl4p) and Ski7p Proteins in 3′-to-5′ Degradation of mRNA | Full Text | References | PDF (1.8 MB)
  • 29 Views
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Article
Participation of the C-Terminal Domain of RNA Polymerase II in Exon Definition during Pre-mRNA Splicing
Changqing Zeng & Susan M. Berget
Pages: 8290-8301
Published online: 28 Mar 2023
AbstractforParticipation of the C-Terminal Domain of RNA Polymerase II in Exon Definition during Pre-mRNA Splicing | Full Text | References | PDF (1.9 MB)
  • 13 Views
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Cell Growth and Development

Article
Analysis of Fission Yeast Primase Defines the Checkpoint Responses to Aberrant S Phase Initiation
Siyuan Tan & Teresa S.-F. Wang
Pages: 7853-7866
Published online: 28 Mar 2023
AbstractforAnalysis of Fission Yeast Primase Defines the Checkpoint Responses to Aberrant S Phase Initiation | Full Text | References | PDF (1.4 MB)
  • 5 Views
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Article
Nckβ Adapter Regulates Actin Polymerization in NIH 3T3 Fibroblasts in Response to Platelet-Derived Growth Factor bb
Min Chen, Hongyun She, Airie Kim, David T. Woodley & Wei Li
Pages: 7867-7880
Published online: 28 Mar 2023
AbstractforNckβ Adapter Regulates Actin Polymerization in NIH 3T3 Fibroblasts in Response to Platelet-Derived Growth Factor bb | Full Text | References | PDF (2.4 MB)
  • 18 Views
  • 68 CrossRef citations
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Article
Proapoptotic p53-Interacting Protein 53BP2 Is Induced by UV Irradiation but Suppressed by p53
Charles D. Lopez, Yi Ao, Larry H. Rohde, Tomas D. Perez, Daniel J. O'Connor, Xin Lu, James M. Ford & Louie Naumovski
Pages: 8018-8025
Published online: 28 Mar 2023
AbstractforProapoptotic p53-Interacting Protein 53BP2 Is Induced by UV Irradiation but Suppressed by p53 | Full Text | References | PDF (2.1 MB)
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Article
ets-2 Is a Target for an Akt (Protein Kinase B)/Jun N-Terminal Kinase Signaling Pathway in Macrophages of motheaten-viable Mutant Mice
James L. Smith, Alicia E. Schaffner, Joseph K. Hofmeister, Matthew Hartman, Guo Wei, David Forsthoefel, David A. Hume & Michael C. Ostrowski
Pages: 8026-8034
Published online: 28 Mar 2023
Abstractforets-2 Is a Target for an Akt (Protein Kinase B)/Jun N-Terminal Kinase Signaling Pathway in Macrophages of motheaten-viable Mutant Mice | Full Text | References | PDF (1.6 MB)
  • 21 Views
  • 56 CrossRef citations
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Article
Positive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the p85α Regulatory Subunit
Kohjiro Ueki, Petra Algenstaedt, Franck Mauvais-Jarvis & C. Ronald Kahn
Pages: 8035-8046
Published online: 28 Mar 2023
AbstractforPositive and Negative Regulation of Phosphoinositide 3-Kinase-Dependent Signaling Pathways by Three Different Gene Products of the p85α Regulatory Subunit | Full Text | References | PDF (1.3 MB)
  • 43 Views
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Article
Role of Phosphoinositide 3-Kinase and Endocytosis in Nerve Growth Factor-Induced Extracellular Signal-Regulated Kinase Activation via Ras and Rap1
Randall D. York, Derek C. Molliver, Savraj S. Grewal, Paula E. Stenberg, Edwin W. McCleskey & Philip J. S. Stork
Pages: 8069-8083
Published online: 28 Mar 2023
AbstractforRole of Phosphoinositide 3-Kinase and Endocytosis in Nerve Growth Factor-Induced Extracellular Signal-Regulated Kinase Activation via Ras and Rap1 | Full Text | References | PDF (2.5 MB)
  • 32 Views
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Article
Ral GTPases Contribute to Regulation of Cyclin D1 through Activation of NF-κB
Dale O. Henry, Serge A. Moskalenko, Kiran J. Kaur, Maofu Fu, Richard G. Pestell, Jacques H. Camonis & Michael A. White
Pages: 8084-8092
Published online: 28 Mar 2023
AbstractforRal GTPases Contribute to Regulation of Cyclin D1 through Activation of NF-κB | Full Text | References | PDF (1.1 MB)
  • 17 Views
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Article
Tryptophan Permease Gene TAT2 Confers High-Pressure Growth in Saccharomyces cerevisiae
Fumiyoshi Abe & Koki Horikoshi
Pages: 8093-8102
Published online: 28 Mar 2023
AbstractforTryptophan Permease Gene TAT2 Confers High-Pressure Growth in Saccharomyces cerevisiae | Full Text | References | PDF (566.8 KB)
  • 38 Views
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Article
Inactivation of Smad-Transforming Growth Factor β Signaling by Ca2+-Calmodulin-Dependent Protein Kinase II
Stephen J. Wicks, Stephen Lui, Nadia Abdel-Wahab, Roger M. Mason & Andrew Chantry
Pages: 8103-8111
Published online: 28 Mar 2023
AbstractforInactivation of Smad-Transforming Growth Factor β Signaling by Ca2+-Calmodulin-Dependent Protein Kinase II | Full Text | References | PDF (1.3 MB)
  • 75 Views
  • 125 CrossRef citations
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Article
Loss of a Protein Phosphatase 2A Regulatory Subunit (Cdc55p) Elicits Improper Regulation of Swe1p Degradation
Haifeng Yang, Wei Jiang, Matthew Gentry & Richard L. Hallberg
Pages: 8143-8156
Published online: 28 Mar 2023
AbstractforLoss of a Protein Phosphatase 2A Regulatory Subunit (Cdc55p) Elicits Improper Regulation of Swe1p Degradation | Full Text | References | PDF (6.3 MB)
  • 12 Views
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Article
Profilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties
Anja Lambrechts, Attila Braun, Veronique Jonckheere, Attila Aszodi, Lorene M. Lanier, Johan Robbens, Inge Van Colen, Joël Vandekerckhove, Reinhard Fässler & Christophe Ampe
Pages: 8209-8219
Published online: 28 Mar 2023
AbstractforProfilin II Is Alternatively Spliced, Resulting in Profilin Isoforms That Are Differentially Expressed and Have Distinct Biochemical Properties | Full Text | References | PDF (2.4 MB)
  • 22 Views
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Article
Roughex Mediates G1 Arrest through a Physical Association with Cyclin A
Sergei N. Avedisov, Irina Krasnoselskaya, Mark Mortin & Barbara J. Thomas
Pages: 8220-8229
Published online: 28 Mar 2023
AbstractforRoughex Mediates G1 Arrest through a Physical Association with Cyclin A | Full Text | References | PDF (7.9 MB)
  • 12 Views
  • 24 CrossRef citations
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Article
Human Scribble (Vartul) Is Targeted for Ubiquitin-Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin-Protein Ligase
Shunsuke Nakagawa & Jon M. Huibregtse
Pages: 8244-8253
Published online: 28 Mar 2023
AbstractforHuman Scribble (Vartul) Is Targeted for Ubiquitin-Mediated Degradation by the High-Risk Papillomavirus E6 Proteins and the E6AP Ubiquitin-Protein Ligase | Full Text | References | PDF (2.8 MB)
  • 60 Views
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Article
Elevated Levels of Hepatocyte Nuclear Factor 3β in Mouse Hepatocytes Influence Expression of Genes Involved in Bile Acid and Glucose Homeostasis
Francisco M. Rausa, Yongjun Tan, Heping Zhou, Kyung W. Yoo, Donna Beer Stolz, Simon C. Watkins, Roberta R. Franks, Terry G. Unterman & Robert H. Costa
Pages: 8264-8282
Published online: 28 Mar 2023
AbstractforElevated Levels of Hepatocyte Nuclear Factor 3β in Mouse Hepatocytes Influence Expression of Genes Involved in Bile Acid and Glucose Homeostasis | Full Text | References | PDF (9.2 MB)
  • 15 Views
  • 85 CrossRef citations
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Nucleocytoplasmic Communication

Article
In Yeast, the 3′ Untranslated Region or the Presequence of ATM1 Is Required for the Exclusive Localization of Its mRNA to the Vicinity of Mitochondria
M. Corral-Debrinski, C. Blugeon & C. Jacq
Pages: 7881-7892
Published online: 28 Mar 2023
AbstractforIn Yeast, the 3′ Untranslated Region or the Presequence of ATM1 Is Required for the Exclusive Localization of Its mRNA to the Vicinity of Mitochondria | Full Text | References | PDF (4.6 MB)
  • 63 Views
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Article
Functional Characterization of Nuclear Localization Signals in Yeast Sm Proteins
Rémy Bordonné
Pages: 7943-7954
Published online: 28 Mar 2023
AbstractforFunctional Characterization of Nuclear Localization Signals in Yeast Sm Proteins | Full Text | References | PDF (3.5 MB)
  • 51 Views
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Article
Identification of Novel Saccharomyces cerevisiaeProteins with Nuclear Export Activity: Cell Cycle-Regulated Transcription Factor Ace2p Shows Cell Cycle-Independent Nucleocytoplasmic Shuttling
Torben Heick Jensen, Megan Neville, Jean Christophe Rain, Terri McCarthy, Pierre Legrain & Michael Rosbash
Pages: 8047-8058
Published online: 28 Mar 2023
AbstractforIdentification of Novel Saccharomyces cerevisiaeProteins with Nuclear Export Activity: Cell Cycle-Regulated Transcription Factor Ace2p Shows Cell Cycle-Independent Nucleocytoplasmic Shuttling | Full Text | References | PDF (1.7 MB)
  • 20 Views
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Cell and Organelle Structure and Assembly

Article
Saccharomyces cerevisiae Expresses Three Functionally Distinct Homologues of the Nramp Family of Metal Transporters
Matthew E. Portnoy, Xiu Fen Liu & Valeria Cizewski Culotta
Pages: 7893-7902
Published online: 28 Mar 2023
AbstractforSaccharomyces cerevisiae Expresses Three Functionally Distinct Homologues of the Nramp Family of Metal Transporters | Full Text | References | PDF (2.6 MB)
  • 36 Views
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Article
Yeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus
Takeshi Sasaki, Akio Toh-e & Yoshiko Kikuchi
Pages: 7971-7979
Published online: 28 Mar 2023
AbstractforYeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus | Full Text | References | PDF (3.3 MB)
  • 73 Views
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Dna Dynamics and Chromosome Structure

Article
The Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire
Kefei Yu & Michael R. Lieber
Pages: 7914-7921
Published online: 28 Mar 2023
AbstractforThe Nicking Step in V(D)J Recombination Is Independent of Synapsis: Implications for the Immune Repertoire | Full Text | References | PDF (1 MB)
  • 9 Views
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Article
Schizosaccharomyces pombe Hsk1p Is a Potential Cds1p Target Required for Genome Integrity
Hilary A. Snaith, Grant W. Brown & Susan L. Forsburg
Pages: 7922-7932
Published online: 28 Mar 2023
AbstractforSchizosaccharomyces pombe Hsk1p Is a Potential Cds1p Target Required for Genome Integrity | Full Text | References | PDF (2.5 MB)
  • 19 Views
  • 67 CrossRef citations
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Article
Defining the Roles of Nucleotide Excision Repair and Recombination in the Repair of DNA Interstrand Cross-Links in Mammalian Cells
Inusha U. De Silva, Peter J. McHugh, Peter H. Clingen & John A. Hartley
Pages: 7980-7990
Published online: 28 Mar 2023
AbstractforDefining the Roles of Nucleotide Excision Repair and Recombination in the Repair of DNA Interstrand Cross-Links in Mammalian Cells | Full Text | References | PDF (705.4 KB)
  • 62 Views
  • 319 CrossRef citations
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Article
Telomere Folding Is Required for the Stable Maintenance of Telomere Position Effects in Yeast
Derik de Bruin, Sara M. Kantrow, Rachel A. Liberatore & Virginia A. Zakian
Pages: 7991-8000
Published online: 28 Mar 2023
AbstractforTelomere Folding Is Required for the Stable Maintenance of Telomere Position Effects in Yeast | Full Text | References | PDF (859.2 KB)
  • 10 Views
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Article
Replication past O6-Methylguanine by Yeast and Human DNA Polymerase η
Lajos Haracska, Satya Prakash & Louise Prakash
Pages: 8001-8007
Published online: 28 Mar 2023
AbstractforReplication past O6-Methylguanine by Yeast and Human DNA Polymerase η | Full Text | References | PDF (771.7 KB)
  • 13 Views
  • 100 CrossRef citations
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Article
Recombinogenic Flap Ligation Pathway for Intrinsic Repair of Topoisomerase IB-Induced Double-Strand Breaks
Chonghui Cheng & Stewart Shuman
Pages: 8059-8068
Published online: 28 Mar 2023
AbstractforRecombinogenic Flap Ligation Pathway for Intrinsic Repair of Topoisomerase IB-Induced Double-Strand Breaks | Full Text | References | PDF (1.1 MB)
  • 7 Views
  • 20 CrossRef citations
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Article
DNA Replication Is Required To Elicit Cellular Responses to Psoralen-Induced DNA Interstrand Cross-Links
Yassmine M. N. Akkari, Raynard L. Bateman, Carol A. Reifsteck, Susan B. Olson & Markus Grompe
Pages: 8283-8289
Published online: 28 Mar 2023
AbstractforDNA Replication Is Required To Elicit Cellular Responses to Psoralen-Induced DNA Interstrand Cross-Links | Full Text | References | PDF (4.8 MB)
  • 20 Views
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Transcriptional Regulation

Article
Discrete Roles for Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor in Recruiting Nuclear Receptor Coactivators
Wen Yang, Christophe Rachez & Leonard P. Freedman
Pages: 8008-8017
Published online: 28 Mar 2023
AbstractforDiscrete Roles for Peroxisome Proliferator-Activated Receptor γ and Retinoid X Receptor in Recruiting Nuclear Receptor Coactivators | Full Text | References | PDF (1.2 MB)
  • 21 Views
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Article
Target Selectivity of Bicoid Is Dependent on Nonconsensus Site Recognition and Protein-Protein Interaction
Chen Zhao, Vrushank Dave, Fan Yang, Tom Scarborough & Jun Ma
Pages: 8112-8123
Published online: 28 Mar 2023
AbstractforTarget Selectivity of Bicoid Is Dependent on Nonconsensus Site Recognition and Protein-Protein Interaction | Full Text | References | PDF (1 MB)
  • 7 Views
  • 24 CrossRef citations
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Article
Multiple Mechanisms of Suppression Circumvent Transcription Defects in an RNA Polymerase Mutant
Qian Tan, Xin Li, Parag P. Sadhale, Takenori Miyao & Nancy A. Woychik
Pages: 8124-8133
Published online: 28 Mar 2023
AbstractforMultiple Mechanisms of Suppression Circumvent Transcription Defects in an RNA Polymerase Mutant | Full Text | References | PDF (1.6 MB)
  • 9 Views
  • 24 CrossRef citations
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Article
Mechanism of Promoter Melting by the Xeroderma Pigmentosum Complementation Group B Helicase of Transcription Factor IIH Revealed by Protein-DNA Photo-Cross-Linking
Maxime Douziech, Frédéric Coin, Jean-Marc Chipoulet, Yoko Arai, Yoshiaki Ohkuma, Jean-Marc Egly & Benoit Coulombe
Pages: 8168-8177
Published online: 28 Mar 2023
AbstractforMechanism of Promoter Melting by the Xeroderma Pigmentosum Complementation Group B Helicase of Transcription Factor IIH Revealed by Protein-DNA Photo-Cross-Linking | Full Text | References | PDF (3.2 MB)
  • 22 Views
  • 60 CrossRef citations
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Article
Inhibition of p300 Histone Acetyltransferase by Viral Interferon Regulatory Factor
M. Li, B. Damania, X. Alvarez, V. Ogryzko, K. Ozato & J. U. Jung
Pages: 8254-8263
Published online: 28 Mar 2023
AbstractforInhibition of p300 Histone Acetyltransferase by Viral Interferon Regulatory Factor | Full Text | References | PDF (3.1 MB)
  • 17 Views
  • 110 CrossRef citations
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Telomerase-Associated Protein TEP1 Is Not Essential for Telomerase Activity or Telomere Length Maintenance In Vivo
Yie Liu, Bryan E. Snow, M. Prakash Hande, Gabriela Baerlocher, Valerie A. Kickhoefer, David Yeung, Andrew Wakeham, Annick Itie, David P. Siderovski, Peter M. Lansdorp, Murray O. Robinson & Lea Harrington
Pages: 8178-8184
Published online: 28 Mar 2023
AbstractforTelomerase-Associated Protein TEP1 Is Not Essential for Telomerase Activity or Telomere Length Maintenance In Vivo | Full Text | References | PDF (810.6 KB)
  • 17 Views
  • 55 CrossRef citations
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