35
Views
116
CrossRef citations to date
0
Altmetric
Gene Expression

Novel Upf2p Orthologues Suggest a Functional Link between Translation Initiation and Nonsense Surveillance Complexes

, , , &
Pages 8944-8957 | Received 18 May 2000, Accepted 05 Sep 2000, Published online: 28 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Aleksandra Siwaszek, Marta Ukleja & Andrzej Dziembowski. (2014) Proteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systems. RNA Biology 11:9, pages 1122-1136.
Read now
Ana M. Matia-González, Ayesha Hasan, Gøril H. Moe, Juan Mata & Miguel A. Rodríguez-Gabriel. (2013) Functional characterization of Upf1 targets in Schizosaccharomyces pombe. RNA Biology 10:6, pages 1057-1065.
Read now
Lisa Johns, Andrew Grimson, Sherry L. Kuchma, Carrie Loushin Newman & Philip Anderson. (2007) Caenorhabditis elegans SMG-2 Selectively Marks mRNAs Containing Premature Translation Termination Codons. Molecular and Cellular Biology 27:16, pages 5630-5638.
Read now
Miguel A. Rodríguez-Gabriel, Stephen Watt, Jürg Bähler & Paul Russell. (2006) Upf1, an RNA Helicase Required for Nonsense-Mediated mRNA Decay, Modulates the Transcriptional Response to Oxidative Stress in Fission Yeast. Molecular and Cellular Biology 26:17, pages 6347-6356.
Read now
Weirong Wang, Iván J. Cajigas, Stuart W. Peltz, Miles F. Wilkinson & Carlos I. González. (2006) Role for Upf2p Phosphorylation in Saccharomyces cerevisiae Nonsense-Mediated mRNA Decay. Molecular and Cellular Biology 26:9, pages 3390-3400.
Read now
Jürgen Wittmann, Elly M. Hol & Hans-Martin Jäck. (2006) hUPF2 Silencing Identifies Physiologic Substrates of Mammalian Nonsense-Mediated mRNA Decay. Molecular and Cellular Biology 26:4, pages 1272-1287.
Read now
Andrew Grimson, Sean O'Connor, Carrie Loushin Newman & Philip Anderson. (2004) SMG-1 Is a Phosphatidylinositol Kinase-Related Protein Kinase Required for Nonsense-Mediated mRNA Decay in Caenorhabditis elegans. Molecular and Cellular Biology 24:17, pages 7483-7490.
Read now
Hui He, Tobias von der Haar, C. Ranjit Singh, Miki Ii, Bin Li, Alan G. Hinnebusch, John E. G. McCarthy & Katsura Asano. (2003) The Yeast Eukaryotic Initiation Factor 4G (eIF4G) HEAT Domain Interacts with eIF1 and eIF5 and Is Involved in Stringent AUG Selection. Molecular and Cellular Biology 23:15, pages 5431-5445.
Read now
Jens Lykke-Andersen. (2002) Identification of a Human Decapping Complex Associated with hUpf Proteins in Nonsense-Mediated Decay. Molecular and Cellular Biology 22:23, pages 8114-8121.
Read now

Articles from other publishers (107)

G. A. Zhouravleva, S. A. Bondarev, O. M. Zemlyanko & S. E. Moskalenko. (2022) Role of Proteins Interacting with the eRF1 and eRF3 Release Factors in the Regulation of Translation and Prionization. Molecular Biology 56:2, pages 147-165.
Crossref
Kazumi Nakano, Nobuaki Karasawa, Masaaki Hashizume, Yuetsu Tanaka, Takeo Ohsugi, Kaoru Uchimaru & Toshiki Watanabe. (2022) Elucidation of the Mechanism of Host NMD Suppression by HTLV-1 Rex: Dissection of Rex to Identify the NMD Inhibitory Domain. Viruses 14:2, pages 344.
Crossref
Boris Zinshteyn, Niladri K. Sinha, Syed Usman Enam, Benjamin Koleske & Rachel Green. (2021) Translational repression of NMD targets by GIGYF2 and EIF4E2. PLOS Genetics 17:10, pages e1009813.
Crossref
Bhagyashree Deka, Pratap Chandra & Kusum Kumari Singh. (2021) Functional roles of human Up-frameshift suppressor 3 (UPF3) proteins: From nonsense-mediated mRNA decay to neurodevelopmental disorders. Biochimie 180, pages 10-22.
Crossref
Yang Zhao, Xiang Ye, Myriam Shehata, William Dunker, Zhihang Xie & John Karijolich. (2020) The RNA quality control pathway nonsense-mediated mRNA decay targets cellular and viral RNAs to restrict KSHV. Nature Communications 11:1.
Crossref
Tatsuaki Kurosaki, Maximilian W. Popp & Lynne E. Maquat. (2019) Quality and quantity control of gene expression by nonsense-mediated mRNA decay. Nature Reviews Molecular Cell Biology 20:7, pages 406-420.
Crossref
Etienne Raimondeau, Joshua C. BuftonChristiane Schaffitzel. (2018) New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors. Biochemical Society Transactions 46:3, pages 503-512.
Crossref
Puneet Gupta & Yan-Ruide Li. (2017) Upf proteins: highly conserved factors involved in nonsense mRNA mediated decay. Molecular Biology Reports 45:1, pages 39-55.
Crossref
Kazunori Kume, Helena Cantwell, Frank R. Neumann, Andrew W. Jones, Ambrosius P. Snijders & Paul Nurse. (2017) A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control. PLOS Genetics 13:5, pages e1006767.
Crossref
Daniel Keifenheim, Xi-Ming Sun, Edridge D’Souza, Makoto J. Ohira, Mira Magner, Michael B. Mayhew, Samuel Marguerat & Nicholas Rhind. (2017) Size-Dependent Expression of the Mitotic Activator Cdc25 Suggests a Mechanism of Size Control in Fission Yeast. Current Biology 27:10, pages 1491-1497.e4.
Crossref
Ok Hyun Park, Joori Park, Mira Yu, Hyoung-Tae An, Jesang Ko & Yoon Ki Kim. (2016) Identification and molecular characterization of cellular factors required for glucocorticoid receptor-mediated mRNA decay. Genes & Development 30:18, pages 2093-2105.
Crossref
Franziska Ottens & Niels H. Gehring. (2016) Physiological and pathophysiological role of nonsense-mediated mRNA decay. Pflügers Archiv - European Journal of Physiology 468:6, pages 1013-1028.
Crossref
Jonathan O Nelson, Kristin A Moore, Alex Chapin, Julie Hollien & Mark M Metzstein. (2016) Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability. eLife 5.
Crossref
Nancy Martínez-Montiel, Laura Morales-Lara, Julio M. Hernández-Pérez & Rebeca D. Martínez-Contreras. (2016) In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis. PLOS ONE 11:2, pages e0148191.
Crossref
Tatsuaki Kurosaki & Lynne E. Maquat. (2016) Nonsense-mediated mRNA decay in humans at a glance. Journal of Cell Science.
Crossref
Greco Hernández, Vincent G. Osnaya, Alejandra García & Mitzli X. Velasco. 2016. Evolution of the Protein Synthesis Machinery and Its Regulation. Evolution of the Protein Synthesis Machinery and Its Regulation 81 107 .
Lara Ajamian, Karen Abel, Shringar Rao, Kishanda Vyboh, Francisco García-de-Gracia, Ricardo Soto-Rifo, Andreas Kulozik, Niels Gehring & Andrew Mouland. (2015) HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA. Biomolecules 5:4, pages 2808-2839.
Crossref
Takashi Sutani, Toyonori Sakata, Ryuichiro Nakato, Koji Masuda, Mai Ishibashi, Daisuke Yamashita, Yutaka Suzuki, Tatsuya Hirano, Masashige Bando & Katsuhiko Shirahige. (2015) Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation. Nature Communications 6:1.
Crossref
Zaineb Fourati, Bijoyita Roy, Claudia Millan, Pierre-Damien Coureux, Stéphanie Kervestin, Herman van Tilbeurgh, Feng He, Isabel Usón, Allan Jacobson & Marc Graille. (2014) A Highly Conserved Region Essential for NMD in the Upf2 N-Terminal Domain. Journal of Molecular Biology 426:22, pages 3689-3702.
Crossref
Lam Son Nguyen, Miles F. Wilkinson & Jozef Gecz. (2014) Nonsense-mediated mRNA decay: Inter-individual variability and human disease. Neuroscience & Biobehavioral Reviews 46, pages 175-186.
Crossref
Takeshi Hayashi, Masahiro Ebe, Koji Nagao, Aya Kokubu, Kenichi Sajiki & Mitsuhiro Yanagida. (2014) Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex . Genes to Cells 19:7, pages 541-554.
Crossref
Alex Chapin, Hao Hu, Shawn G Rynearson, Julie Hollien, Mark Yandell & Mark M Metzstein. (2014) In Vivo Determination of Direct Targets of the Nonsense-Mediated Decay Pathway in Drosophila . G3 Genes|Genomes|Genetics 4:3, pages 485-496.
Crossref
Kinga P. Orlowska, Kamila Klosowska, Roman J. Szczesny, Dominik Cysewski, Pawel S. Krawczyk & Andrzej Dziembowski. (2013) A new strategy for gene targeting and functional proteomics using the DT40 cell line. Nucleic Acids Research 41:17, pages e167-e167.
Crossref
Christoph Schweingruber, Simone C. Rufener, David Zünd, Akio Yamashita & Oliver Mühlemann. (2013) Nonsense-mediated mRNA decay — Mechanisms of substrate mRNA recognition and degradation in mammalian cells. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1829:6-7, pages 612-623.
Crossref
Zhi L Teo, Daniel J Park, Elena Provenzano, Catherine A Chatfield, Fabrice A Odefrey, Tu Nguyen-Dumont, James G Dowty, John L Hopper, Ingrid Winship, David E Goldgar & Melissa C Southey. (2013) Prevalence of PALB2 mutations in Australasian multiple-case breast cancer families. Breast Cancer Research 15:1.
Crossref
I. M. Palacios. (2012) Nonsense-mediated mRNA decay: from mechanistic insights to impacts on human health. Briefings in Functional Genomics 12:1, pages 25-36.
Crossref
Stephanie Kervestin & Allan Jacobson. (2012) NMD: a multifaceted response to premature translational termination. Nature Reviews Molecular Cell Biology 13:11, pages 700-712.
Crossref
Lulu Huang & Miles F. Wilkinson. (2012) Regulation of nonsense-mediated mRNA decay. Wiley Interdisciplinary Reviews: RNA 3:6, pages 807-828.
Crossref
Nina Riehs-Kearnan, Jiradet Gloggnitzer, Bettina Dekrout, Claudia Jonak & Karel Riha. (2012) Aberrant growth and lethality of Arabidopsis deficient in nonsense-mediated RNA decay factors is caused by autoimmune-like response. Nucleic Acids Research 40:12, pages 5615-5624.
Crossref
Pamela A. Frischmeyer-Guerrerio, Robert A. Montgomery, Daniel S. Warren, Sara K. Cooke, Johannes Lutz, Christopher J. Sonnenday, Anthony L. Guerrerio & Harry C. Dietz. (2011) Perturbation of thymocyte development in nonsense-mediated decay (NMD)-deficient mice. Proceedings of the National Academy of Sciences 108:26, pages 10638-10643.
Crossref
Marta Vicente-CrespoIsabel M. Palacios. (2010) Nonsense-mediated mRNA decay and development: shoot the messenger to survive?. Biochemical Society Transactions 38:6, pages 1500-1505.
Crossref
Madhuri Bhuvanagiri, Anna M. Schlitter, Matthias W. Hentze & Andreas E. Kulozik. (2010) NMD: RNA biology meets human genetic medicine. Biochemical Journal 430:3, pages 365-377.
Crossref
Portia Gloria Loh & Haiwei Song. 2010. RNA Helicases. RNA Helicases 189 212 .
Jikai Wen & Saverio Brogna. (2010) Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe. The EMBO Journal 29:9, pages 1537-1551.
Crossref
Lawrence B. Gardner. (2010) Nonsense-Mediated RNA Decay Regulation by Cellular Stress: Implications for Tumorigenesis. Molecular Cancer Research 8:3, pages 295-308.
Crossref
Pamela Nicholson, Hasmik Yepiskoposyan, Stefanie Metze, Rodolfo Zamudio Orozco, Nicole Kleinschmidt & Oliver Mühlemann. (2009) Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors. Cellular and Molecular Life Sciences 67:5, pages 677-700.
Crossref
Marcello Clerici, André Mourão, Irina Gutsche, Niels H Gehring, Matthias W Hentze, Andreas Kulozik, Jan Kadlec, Michael Sattler & Stephen Cusack. (2009) Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2. The EMBO Journal 28:15, pages 2293-2306.
Crossref
Indrani Rebbapragada & Jens Lykke-Andersen. (2009) Execution of nonsense-mediated mRNA decay: what defines a substrate?. Current Opinion in Cell Biology 21:3, pages 394-402.
Crossref
Greco Hernández. (2009) On the origin of the cap-dependent initiation of translation in eukaryotes. Trends in Biochemical Sciences 34:4, pages 166-175.
Crossref
Ana Luísa Silva & Luísa Romão. (2009) The mammalian nonsense‐mediated mRNA decay pathway: To decay or not to decay! Which players make the decision?. FEBS Letters 583:3, pages 499-505.
Crossref
Chenguang Gong, Yoon Ki Kim, Collynn F. Woeller, Yalan Tang & Lynne E. Maquat. (2009) SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes & Development 23:1, pages 54-66.
Crossref
Almoutassem B Zetoune, Sandra Fontanière, Delphine Magnin, Olga Anczuków, Monique Buisson, Chang X Zhang & Sylvie Mazoyer. (2008) Comparison of nonsense-mediated mRNA decay efficiency in various murine tissues. BMC Genetics 9:1.
Crossref
Yi-Hsiu Chen, Li-Hsin Su, Yu-Chang Huang, Yi-Ting Wang, Yu-Yun Kao & Chin-Hung Sun. (2008) UPF1, a Conserved Nonsense-Mediated mRNA Decay Factor, Regulates Cyst Wall Protein Transcripts in Giardia lamblia. PLoS ONE 3:10, pages e3609.
Crossref
Shinya Takahashi, Yasuhiro Araki, Yuriko Ohya, Takeshi Sakuno, Shin-Ichi Hoshino, Kenji Kontani, Hiroshi Nishina & Toshiaki Katada. (2008) Upf1 potentially serves as a RING-related E3 ubiquitin ligase via its association with Upf3 in yeast. RNA 14:9, pages 1950-1958.
Crossref
Olaf Isken & Lynne E. Maquat. (2008) The multiple lives of NMD factors: balancing roles in gene and genome regulation. Nature Reviews Genetics 9:9, pages 699-712.
Crossref
Jürgen Wittmann & Hans-Martin Jäck. 2008. RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways. RNA Turnover in Eukaryotes: Analysis of Specialized and Quality Control RNA Decay Pathways 263 294 .
Gabriele Neu‐Yilik & Andreas E. Kulozik. 2008. 185 243 .
Arnaud Boisnard, Laurence Albar, Deless Thiéméle, Myriam Rondeau & Alain Ghesquière. (2007) Evaluation of genes from eIF4E and eIF4G multigenic families as potential candidates for partial resistance QTLs to Rice yellow mottle virus in rice. Theoretical and Applied Genetics 116:1, pages 53-62.
Crossref
Guramrit Singh, Steffen Jakob, Mark G. Kleedehn & Jens Lykke-Andersen. (2007) Communication with the Exon-Junction Complex and Activation of Nonsense-Mediated Decay by Human Upf Proteins Occur in the Cytoplasm. Molecular Cell 27:5, pages 780-792.
Crossref
Olaf Isken & Lynne E. Maquat. (2007) Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function. Genes & Development 21:15, pages 1833-3856.
Crossref
Yao-Fu ChangJ. Saadi ImamMiles F. Wilkinson. (2007) The Nonsense-Mediated Decay RNA Surveillance Pathway. Annual Review of Biochemistry 76:1, pages 51-74.
Crossref
A.M. Eeds, D. Mortlock, R. Wade-Martins & M.L. Summar. (2007) Assessing the Functional Characteristics of Synonymous and Nonsynonymous Mutation Candidates by Use of Large DNA Constructs. The American Journal of Human Genetics 80:4, pages 740-750.
Crossref
Igor Y. Morozov, Susana Negrete-Urtasun, Joan Tilburn, Christine A. Jansen, Mark X. Caddick & Herbert N. ArstJr.Jr.. (2006) Nonsense-Mediated mRNA Decay Mutation in Aspergillus nidulans . Eukaryotic Cell 5:11, pages 1838-1846.
Crossref
Laura Marín-Vinader, Siebe T. van Genesen & Nicolette H. Lubsen. (2006) mRNA made during heat shock enters the first round of translation. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1759:11-12, pages 535-542.
Crossref
Yuriko Harigaya, Hirotsugu Tanaka, Soichiro Yamanaka, Kayoko Tanaka, Yoshinori Watanabe, Chihiro Tsutsumi, Yuji Chikashige, Yasushi Hiraoka, Akira Yamashita & Masayuki Yamamoto. (2006) Selective elimination of messenger RNA prevents an incidence of untimely meiosis. Nature 442:7098, pages 45-50.
Crossref
Nadia Amrani, Matthew S. Sachs & Allan Jacobson. (2006) Early nonsense: mRNA decay solves a translational problem. Nature Reviews Molecular Cell Biology 7:6, pages 415-425.
Crossref
Lynne E. Maquat. 2006. Nonsense-Mediated mRNA Decay. Nonsense-Mediated mRNA Decay 77 88 .
Isao Kashima, Akio Yamashita, Natsuko Izumi, Naoyuki Kataoka, Ryo Morishita, Shinichi Hoshino, Mutsuhito Ohno, Gideon Dreyfuss & Shigeo Ohno. (2006) Binding of a novel SMG-1–Upf1–eRF1–eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes & Development 20:3, pages 355-367.
Crossref
Michael Lynch. (2006) The Origins of Eukaryotic Gene Structure. Molecular Biology and Evolution 23:2, pages 450-468.
Crossref
Joshua T Mendell & Harry C Dietz. 2001. eLS. eLS.
Akio Yamashita, Tsung-Cheng Chang, Yukiko Yamashita, Wenmiao Zhu, Zhenping Zhong, Chyi-Ying A Chen & Ann-Bin Shyu. (2005) Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover. Nature Structural & Molecular Biology 12:12, pages 1054-1063.
Crossref
Akio Yamashita, Isao Kashima & Shigeo Ohno. (2005) The role of SMG-1 in nonsense-mediated mRNA decay. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1754:1-2, pages 305-315.
Crossref
Niels H. Gehring, Joachim B. Kunz, Gabriele Neu-Yilik, Stephen Breit, Marcelo H. Viegas, Matthias W. Hentze & Andreas E. Kulozik. (2005) Exon-Junction Complex Components Specify Distinct Routes of Nonsense-Mediated mRNA Decay with Differential Cofactor Requirements. Molecular Cell 20:1, pages 65-75.
Crossref
Lynne E. Maquat. (2005) Nonsense-mediated mRNA decay in mammals. Journal of Cell Science 118:9, pages 1773-1776.
Crossref
Heidi M. Simmons, Brian L. Ruis, Meenal Kapoor, Andrew W. Hudacek & Kathleen F. Conklin. (2005) Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia. Gene 347:1, pages 137-145.
Crossref
Harold C. Smith, Joseph E. Wedekind, Kefang Xie & Mark P. Sowden. 2005. Fine-Tuning of RNA Functions by Modification and Editing. Fine-Tuning of RNA Functions by Modification and Editing 365 400 .
CHAIM WACHTEL, BINGHUI LI, JOSEPH SPERLING & RUTH SPERLING. (2004) Stop codon-mediated suppression of splicing is a novel nuclear scanning mechanism not affected by elements of protein synthesis and NMD. RNA 10:11, pages 1740-1750.
Crossref
JASON W. HARGER & JONATHAN D. DINMAN. (2004) Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough. RNA 10:11, pages 1721-1729.
Crossref
Ângela Inácio, Ana Luísa Silva, Joana Pinto, Xinjun Ji, Ana Morgado, Fátima Almeida, Paula Faustino, João Lavinha, Stephen A. Liebhaber & Luísa Romão. (2004) Nonsense Mutations in Close Proximity to the Initiation Codon Fail to Trigger Full Nonsense-mediated mRNA Decay. Journal of Biological Chemistry 279:31, pages 32170-32180.
Crossref
Kristian E Baker & Roy Parker. (2004) Nonsense-mediated mRNA decay: terminating erroneous gene expression. Current Opinion in Cell Biology 16:3, pages 293-299.
Crossref
KIM M. KEELING, JESSICA LANIER, MING DU, JOE SALAS-MARCO, LIN GAO, ANISA KAENJAK-ANGELETTI & DAVID M. BEDWELL. (2004) Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S. cerevisiae . RNA 10:4, pages 691-703.
Crossref
Jan Kadlec, Elisa Izaurralde & Stephen Cusack. (2004) The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3. Nature Structural & Molecular Biology 11:4, pages 330-337.
Crossref
Jens Lykke-Andersen. (2004) Making structural sense of nonsense-mediated decay. Nature Structural & Molecular Biology 11:4, pages 305-306.
Crossref
Maria A. Ferraiuolo, Chung-Sheng Lee, Lian Wee Ler, Jeanne L. Hsu, Mauro Costa-Mattioli, Ming-Juan Luo, Robin Reed & Nahum Sonenberg. (2004) A nuclear translation-like factor eIF4AIII is recruited to the mRNA during splicing and functions in nonsense-mediated decay. Proceedings of the National Academy of Sciences 101:12, pages 4118-4123.
Crossref
Lynne E. Maquat. (2004) Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics. Nature Reviews Molecular Cell Biology 5:2, pages 89-99.
Crossref
Ajit Nott, Hervé Le Hir & Melissa J. Moore. (2004) Splicing enhances translation in mammalian cells: an additional function of the exon junction complex. Genes & Development 18:2, pages 210-222.
Crossref
Feng He, Xiangrui Li, Phyllis Spatrick, Ryan Casillo, Shuyun Dong & Allan Jacobson. (2003) Genome-Wide Analysis of mRNAs Regulated by the Nonsense-Mediated and 5′ to 3′ mRNA Decay Pathways in Yeast. Molecular Cell 12:6, pages 1439-1452.
Crossref
Tetsuo Ohnishi, Akio Yamashita, Isao Kashima, Thomas Schell, Kirk R. Anders, Andrew Grimson, Takahisa Hachiya, Matthias W. Hentze, Philip Anderson & Shigeo Ohno. (2003) Phosphorylation of hUPF1 Induces Formation of mRNA Surveillance Complexes Containing hSMG-5 and hSMG-7. Molecular Cell 12:5, pages 1187-1200.
Crossref
Fabrice Lejeune, Xiaojie Li & Lynne E. Maquat. (2003) Nonsense-Mediated mRNA Decay in Mammalian Cells Involves Decapping, Deadenylating, and Exonucleolytic Activities. Molecular Cell 12:3, pages 675-687.
Crossref
Guramrit Singh & Jens Lykke-Andersen. (2003) New insights into the formation of active nonsense-mediated decay complexes. Trends in Biochemical Sciences 28:9, pages 464-466.
Crossref
Francesco Carinci, Stefano Volinia, Corrado Rubini, Massimiliano Fioroni, Francesca Francioso, Diego Arcelli, Furio Pezzetti & Adriano Piattelli. (2003) Genetic Profile of Clear Cell Odontogenic Carcinoma. Journal of Craniofacial Surgery 14:3, pages 356-362.
Crossref
Dan Cao & Roy Parker. (2003) Computational Modeling and Experimental Analysis of Nonsense-Mediated Decay in Yeast. Cell 113:4, pages 533-545.
Crossref
Niels H. Gehring, Gabriele Neu-Yilik, Thomas Schell, Matthias W. Hentze & Andreas E. Kulozik. (2003) Y14 and hUpf3b Form an NMD-Activating Complex. Molecular Cell 11:4, pages 939-949.
Crossref
Michael R Culbertson & Peter F Leeds. (2003) Looking at mRNA decay pathways through the window of molecular evolution. Current Opinion in Genetics & Development 13:2, pages 207-214.
Crossref
SHANG-YI CHIU, GUILLAUME SERIN, OSAMU OHARA & LYNNE E. MAQUAT. (2003) Characterization of human Smg5/7a: A protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1 . RNA 9:1, pages 77-87.
Crossref
Joshua T. MendellColette M. J. ap RhysHarry C. Dietz. (2002) Separable Roles for rent1/hUpf1 in Altered Splicing and Decay of Nonsense Transcripts. Science 298:5592, pages 419-422.
Crossref
Eileen Wagner & Jens Lykke-Andersen. (2002) mRNA surveillance: the perfect persist. Journal of Cell Science 115:15, pages 3033-3038.
Crossref
Renee L Shirley, Amanda S Ford, M Rachel Richards, Markus Albertini & Michael R Culbertson. (2002) Nuclear Import of Upf3p Is Mediated by Importin-α/-β and Export to the Cytoplasm Is Required for a Functional Nonsense-Mediated mRNA Decay Pathway in Yeast. Genetics 161:4, pages 1465-1482.
Crossref
Hélène Tourrière, Karim Chebli & Jamal Tazi. (2002) mRNA degradation machines in eukaryotic cells. Biochimie 84:8, pages 821-837.
Crossref
Miles F. Wilkinson & Ann-Bin Shyu. (2002) RNA surveillance by nuclear scanning?. Nature Cell Biology 4:6, pages E144-E147.
Crossref
Jun Wang, Vita M. Vock, Shulin Li, O. Renee Olivas & Miles F. Wilkinson. (2002) A Quality Control Pathway That Down-regulates Aberrant T-cell Receptor (TCR) Transcripts by a Mechanism Requiring UPF2 and Translation. Journal of Biological Chemistry 277:21, pages 18489-18493.
Crossref
Gideon Dreyfuss, V. Narry Kim & Naoyuki Kataoka. (2002) Messenger-RNA-binding proteins and the messages they carry. Nature Reviews Molecular Cell Biology 3:3, pages 195-205.
Crossref
Carol J. Wilusz, Weirong Wang & Stuart W. Peltz. (2001) Curbing the nonsense: the activation and regulation of mRNA surveillance: Figure 1.. Genes & Development 15:21, pages 2781-2785.
Crossref
Susan E Mango. (2001) Stop making nonSense: the C. elegans smg genes. Trends in Genetics 17:11, pages 646-653.
Crossref
Joshua T Mendell & Harry C Dietz. (2001) When the Message Goes Awry. Cell 107:4, pages 411-414.
Crossref
V. Narry KimNaoyuki KataokaGideon Dreyfuss. (2001) Role of the Nonsense-Mediated Decay Factor hUpf3 in the Splicing-Dependent Exon-Exon Junction Complex. Science 293:5536, pages 1832-1836.
Crossref
Jens Lykke-AndersenMei-Di ShuJoan A. Steitz. (2001) Communication of the Position of Exon-Exon Junctions to the mRNA Surveillance Machinery by the Protein RNPS1. Science 293:5536, pages 1836-1839.
Crossref
Akio Yamashita, Tetsuo Ohnishi, Isao Kashima, Yoichi Taya & Shigeo Ohno. (2001) Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay. Genes & Development 15:17, pages 2215-2228.
Crossref
Yasuhito Ishigaki, Xiaojie Li, Guillaume Serin & Lynne E. Maquat. (2001) Evidence for a Pioneer Round of mRNA Translation. Cell 106:5, pages 607-617.
Crossref
Carlos I González, Anirban Bhattacharya, Weirong Wang & Stuart W Peltz. (2001) Nonsense-mediated mRNA decay in Saccharomyces cerevisiae. Gene 274:1-2, pages 15-25.
Crossref
Philip Mitchell & David Tollervey. (2001) mRNA turnover. Current Opinion in Cell Biology 13:3, pages 320-325.
Crossref
Rachel Aronoff, Renee Baran & Jonathan Hodgkin. (2001) Molecular identification of smg-4 , required for mRNA surveillance in C. elegans. Gene 268:1-2, pages 153-164.
Crossref
Carol J. Wilusz, Michael Wormington & Stuart W. Peltz. (2001) The cap-to-tail guide to mRNA turnover. Nature Reviews Molecular Cell Biology 2:4, pages 237-246.
Crossref
Jens Lykke-Andersen. (2001) mRNA quality control: Marking the message for life or death. Current Biology 11:3, pages R88-R91.
Crossref
C.I. GONZALEZ, W. WANG & S.W. PELTZ. (2001) Nonsense-mediated mRNA Decay in Saccharomyces cerevisiae: A Quality Control Mechanism That Degrades Transcripts Harboring Premature Termination Codons. Cold Spring Harbor Symposia on Quantitative Biology 66:0, pages 321-328.
Crossref
L.E. MAQUAT & G. SERIN. (2001) Nonsense-mediated mRNA Decay: Insights into Mechanism from the Cellular Abundance of Human Upf1, Upf2, Upf3, and Upf3X Proteins. Cold Spring Harbor Symposia on Quantitative Biology 66:0, pages 313-320.
Crossref
Jens Lykke-Andersen, Mei-Di Shu & Joan A. Steitz. (2000) Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon. Cell 103:7, pages 1121-1131.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.