42
Views
89
CrossRef citations to date
0
Altmetric
Cell Growth and Development

The Cbl Proto-Oncogene Product Negatively Regulates the Src-Family Tyrosine Kinase Fyn by Enhancing Its Degradation

, , , , , , , & show all
Pages 851-867 | Received 13 Jan 1999, Accepted 28 Oct 1999, Published online: 28 Mar 2023

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Rosemary Poku, Felix Amissah & Jamie K. Alan. (2023) PI3K Functions Downstream of Cdc42 to Drive Cancer phenotypes in a Melanoma Cell Line. Small GTPases 14:1, pages 1-13.
Read now
Jonathan A. Cooper, Tomonori Kaneko & Shawn S. C. Li. (2015) Cell Regulation by Phosphotyrosine-Targeted Ubiquitin Ligases. Molecular and Cellular Biology 35:11, pages 1886-1897.
Read now
Parag Patwardhan & Marilyn D. Resh. (2010) Myristoylation and Membrane Binding Regulate c-Src Stability and Kinase Activity. Molecular and Cellular Biology 30:17, pages 4094-4107.
Read now
Cai Huang. (2010) Roles of E3 ubiquitin ligases in cell adhesion and migration. Cell Adhesion & Migration 4:1, pages 10-18.
Read now
Lakshmi Balagopalan, Valarie A. Barr, Connie L. Sommers, Mira Barda-Saad, Amrita Goyal, Matthew S. Isakowitz & Lawrence E. Samelson. (2007) c-Cbl-Mediated Regulation of LAT-Nucleated Signaling Complexes. Molecular and Cellular Biology 27:24, pages 8622-8636.
Read now
Ana Giannini & Marie-José Bijlmakers. (2004) Regulation of the Src Family Kinase Lck by Hsp90 and Ubiquitination. Molecular and Cellular Biology 24:13, pages 5667-5676.
Read now
Brenda J. Irvin, Brandi L. Williams, Allan E. Nilson, Hannah O. Maynor & Robert T. Abraham. (2000) Pleiotropic Contributions of Phospholipase C-γ1 (PLC-γ1) to T-Cell Antigen Receptor-Mediated Signaling: Reconstitution Studies of a PLC-γ1-Deficient Jurkat T-Cell Line. Molecular and Cellular Biology 20:24, pages 9149-9161.
Read now

Articles from other publishers (82)

Pulak Ranjan Nath, Nikhil Ponnoor Anto, Alex Braiman & Noah Isakov. (2023) Termination of TCR-mediated activation signals is regulated by CrkII-dependent Cbl-mediated ubiquitination and degradation of C3G. Immunobiology 228:2, pages 152342.
Crossref
SanFei Peng & Yang Fu. (2023) FYN: emerging biological roles and potential therapeutic targets in cancer. Journal of Translational Medicine 21:1.
Crossref
Federica Conte & Paola Paci. (2022) Alzheimer’s disease: insights from a network medicine perspective. Scientific Reports 12:1.
Crossref
Leanne E. Wybenga-Groot, Andrea J. Tench, Craig D. Simpson, Jonathan St. Germain, Brian Raught, Michael F. Moran & C. Jane McGlade. (2021) SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function. Journal of Molecular Biology 433:8, pages 166880.
Crossref
Syed Feroj Ahmed, Lori Buetow, Mads Gabrielsen, Sergio Lilla, Gary J. Sibbet, David Sumpton, Sara Zanivan, Ann Hedley, William Clark & Danny T. Huang. (2021) E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis. Oncogene 40:12, pages 2149-2164.
Crossref
Vivian Lee, ThomasD Griffin, Yoko Suzuki-Horiuchi, Lily Wushanley, Yerin Kweon, Christine Marshall, Weijie Li, Elias Ayli, Adele Haimovic, Aliya Hines & JohnT Seykora. (2021) Downregulation of Src-family tyrosine kinases by Srcasm and c-Cbl: A comparative analysis. Journal of Carcinogenesis 20:1, pages 21.
Crossref
Takahisa Kuga, Yuka Yamane, Soujirou Hayashi, Masanari Taniguchi, Naoto Yamaguchi & Nobuyuki Yamagishi. (2020) Depletion of Csk preferentially reduces the protein level of LynA in a Cbl-dependent manner in cancer cells. Scientific Reports 10:1.
Crossref
Scott A. Nadeau, Wei An, Bhopal C. Mohapatra, Insha Mushtaq, Timothy A. Bielecki, Haitao Luan, Neha Zutshi, Gulzar Ahmad, Matthew D. Storck, Masashi Sanada, Seishi Ogawa, Vimla Band & Hamid Band. (2017) Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene. Journal of Biological Chemistry 292:9, pages 3666-3682.
Crossref
Dominique Davidson, Ming-Chao Zhong, Pier Paolo Pandolfi, Silvia Bolland, Ramnik J. Xavier, Brian Seed, Xin Li, Hua Gu & André Veillette. (2016) The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors. Cell Reports 17:10, pages 2776-2788.
Crossref
Piyali Ganguli, Saikat Chowdhury, Rupa Bhowmick & Ram Rup Sarkar. (2015) Temporal protein expression pattern in intracellular signalling cascade during T-cell activation: A computational study. Journal of Biosciences 40:4, pages 769-789.
Crossref
Mark Noble, Margot Mayer-Pröschel, Zaibo Li, Tiefei Dong, Wanchang Cui, Christoph Pröschel, Ibro Ambeskovic, Joerg Dietrich, Ruolan Han, Yin Miranda Yang, Christopher Folts, Jennifer Stripay, Hsing-Yu Chen & Brett M. Stevens. (2015) Redox biology in normal cells and cancer: Restoring function of the redox/Fyn/c-Cbl pathway in cancer cells offers new approaches to cancer treatment. Free Radical Biology and Medicine 79, pages 300-323.
Crossref
Takamichi Shintani, Fusako Ohara-Waki, Akira Kitanaka, Terukazu Tanaka & Yoshitsugu Kubota. (2014) Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase. Blood Cells, Molecules, and Diseases 53:4, pages 211-218.
Crossref
Roman Ginnan, Xiaojing Zou, Paul J. Pfleiderer, Melissa Z. Mercure, Margarida Barroso & Harold A. Singer. (2013) Vascular Smooth Muscle Cell Motility Is Mediated by a Physical and Functional Interaction of Ca2+/Calmodulin-dependent Protein Kinase IIδ2 and Fyn. Journal of Biological Chemistry 288:41, pages 29703-29712.
Crossref
Mojib Javadi, Terri D. Richmond, Kai Huang & Dwayne L. Barber. (2013) CBL Linker Region and RING Finger Mutations Lead to Enhanced Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) Signaling via Elevated Levels of JAK2 and LYN. Journal of Biological Chemistry 288:27, pages 19459-19470.
Crossref
Linda P. O'Reilly, Xiong Zhang & Thomas E. Smithgall. (2013) Individual Src-family tyrosine kinases direct the degradation or protection of the clock protein Timeless via differential ubiquitylation. Cellular Signalling 25:4, pages 860-866.
Crossref
N Sévère, F-X Dieudonné & P J Marie. (2013) E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis. Cell Death & Disease 4:1, pages e463-e463.
Crossref
Rosa Molfetta, Francesca Gasparrini, Angela Santoni & Rossella Paolini. (2013) The Cbl family of ubiquitin ligases regulates FcεRI expression and mast cell activation. Advances in Bioscience and Biotechnology 04:12, pages 1063-1072.
Crossref
Daiju Ichikawa, Miho Mizuno, Takashi Yamamura & Sachiko Miyake. (2011) GRAIL (Gene Related to Anergy in Lymphocytes) Regulates Cytoskeletal Reorganization through Ubiquitination and Degradation of Arp2/3 Subunit 5 and Coronin 1A. Journal of Biological Chemistry 286:50, pages 43465-43474.
Crossref
Q. Pan, F. Qiao, C. Gao, B. Norman, L. Optican & Peggy S. Zelenka. (2011) Cdk5 targets active Src for ubiquitin-dependent degradation by phosphorylating Src(S75). Cellular and Molecular Life Sciences 68:20, pages 3425-3436.
Crossref
Mark A Rainey, Manju George, GuoGuang Ying, Reiko Akakura, Daniel J Burgess, Ed Siefker, Tom Bargar, Lynn Doglio, Susan E Crawford, Gordon L Todd, Venkatesh Govindarajan, Rex A Hess, Vimla Band, Mayumi Naramura & Hamid Band. (2010) The endocytic recycling regulator EHD1 is essential for spermatogenesis and male fertility in mice. BMC Developmental Biology 10:1.
Crossref
Gillian C. Whittaker, Selinda J. Orr, Laura Quigley, Laurel Hughes, Ivo M.B. Francischetti, Weigou Zhang & Daniel W. McVicar. (2010) The Linker for Activation of B Cells (LAB)/Non-T Cell Activation Linker (NTAL) Regulates Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Signaling and Macrophage Inflammatory Responses Independently of the Linker for Activation of T Cells. Journal of Biological Chemistry 285:5, pages 2976-2985.
Crossref
Jun Sung Lee, Ji Eun Lee, Yu Mi Oh, Jong Bae Park, Heonsik Choi, Chung Yeon Choi, In-Hoo Kim, Seung Hoon Lee & Kyungho Choi. (2009) Recruitment of Sprouty1 to Immune Synapse Regulates T Cell Receptor Signaling. The Journal of Immunology 183:11, pages 7178-7186.
Crossref
Alexander C. Klimowicz, Sabine A. Bisson, Karm Hans, Elizabeth M. Long, Henrik C. Hansen & Stephen M. Robbins. (2009) The phytochemical piceatannol induces the loss of CBL and CBL-associated proteins. Molecular Cancer Therapeutics 8:3, pages 602-614.
Crossref
Masato Ikeda & Richard Longnecker. (2009) The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling. Virology 385:1, pages 183-191.
Crossref
George S. Laszlo & Jonathan A. Cooper. (2009) Restriction of Src Activity by Cullin-5. Current Biology 19:2, pages 157-162.
Crossref
Denise L. Gay, Hilda Ramón & Paula M. Oliver. (2008) Cbl- and Nedd4-family ubiquitin ligases: balancing tolerance and immunity. Immunologic Research 42:1-3, pages 51-64.
Crossref
Trond Methi, Torunn Berge, Knut Martin Torgersen & Kjetil Taskén. (2008) Reduced Cbl phosphorylation and degradation of the ζ-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels. European Journal of Immunology 38:9, pages 2557-2563.
Crossref
Ji WuFeng MengHenry Lu, Ling KongWilliam Bornmann, Zhenghong Peng, Moshe Talpaz & Nicholas J. Donato. (2008) Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells. Blood 111:7, pages 3821-3829.
Crossref
Marta Pires de Miranda, Marta Alenquer, Sofia Marques, Lénia Rodrigues, Filipa Lopes, Xosé R. Bustelo & J. Pedro Simas. (2008) The Gammaherpesvirus m2 Protein Manipulates the Fyn/Vav Pathway through a Multidocking Mechanism of Assembly. PLoS ONE 3:2, pages e1654.
Crossref
Ceri M. Wiggins, Hamid Band & Simon J. Cook. (2007) c-Cbl is not required for ERK1/2-dependent degradation of BimEL. Cellular Signalling 19:12, pages 2605-2611.
Crossref
Weijie Li, Christine Marshall, Lijuan Mei, Joel Gelfand & John T. Seykora. (2007) Srcasm Corrects Fyn-induced Epidermal Hyperplasia by Kinase Down-regulation. Journal of Biological Chemistry 282:2, pages 1161-1169.
Crossref
Archana Sanjay, Tsuyoshi Miyazaki, Cecile Itzstein, Enkhtsetseg Purev, William C. Horne & Roland Baron. (2006) Identification and functional characterization of an Src homology domain 3 domain-binding site on Cbl. FEBS Journal 273:23, pages 5442-5456.
Crossref
Sonja E. Gustin, Christine B. F. Thien & Wallace Y. Langdon. (2006) Cbl-b Is a Negative Regulator of Inflammatory Cytokines Produced by IgE-Activated Mast Cells. The Journal of Immunology 177:9, pages 5980-5989.
Crossref
Kristina Masson, Elke Heiss, Hamid BandLars Rönnstrand. (2006) Direct binding of Cbl to Tyr568 and Tyr936 of the stem cell factor receptor/c-Kit is required for ligand-induced ubiquitination, internalization and degradation. Biochemical Journal 399:1, pages 59-67.
Crossref
Gayathri Swaminathan & Alexander Y. Tsygankov. (2006) The Cbl family proteins: Ring leaders in regulation of cell signaling. Journal of Cellular Physiology 209:1, pages 21-43.
Crossref
Hanna Gyllberg, Kajsa Löfgren, Heléne Lindegren & Katarina Bedecs. (2006) Increased Src kinase level results in increased protein tyrosine phosphorylation in scrapie-infected neuronal cell lines. FEBS Letters 580:11, pages 2603-2608.
Crossref
Margaret D Myers, Tomasz Sosinowski, Leonard L Dragone, Carmen White, Hamid Band, Hua Gu & Arthur Weiss. (2005) Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex. Nature Immunology 7:1, pages 57-66.
Crossref
Angela Samaan, Elias Haddad .Wahib Mahana .. (2005) Differential Phosphorylation of c-Cbl in Leukemogenic and Nonleukemogenic HTLV-I Cell Lines. International Journal of Virology 2:1, pages 39-49.
Crossref
Polung Yang & Andrew J. Henderson. (2005) Nef enhances c-Cbl phosphorylation in HIV-infected CD4+ T lymphocytes. Virology 336:2, pages 219-228.
Crossref
Junjie Hu & Stevan R. Hubbard. (2005) Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins. Journal of Biological Chemistry 280:19, pages 18943-18949.
Crossref
Rizaldy P. Scott, Susanna Eketjäll, Helena Aineskog & Carlos F. Ibáñez. (2005) Distinct Turnover of Alternatively Spliced Isoforms of the RET Kinase Receptor Mediated by Differential Recruitment of the Cbl Ubiquitin Ligase. Journal of Biological Chemistry 280:14, pages 13442-13449.
Crossref
Karim Kaabeche, Hind Guenou, Daniel Bouvard, Nadège Didelot, Antoine Listrat & Pierre J. Marie. (2005) Cbl-mediated ubiquitination of α5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation. Journal of Cell Science 118:6, pages 1223-1232.
Crossref
Robert L Geahlen, Misty D Handley & Marietta L Harrison. (2004) Molecular interdiction of Src-family kinase signaling in hematopoietic cells. Oncogene 23:48, pages 8024-8032.
Crossref
Amiya K. Ghosh, Alagarsamy L. Reddi, Navin L. Rao, Lei Duan, Vimla Band & Hamid Band. (2004) Biochemical Basis for the Requirement of Kinase Activity for Cbl-dependent Ubiquitinylation and Degradation of a Target Tyrosine Kinase. Journal of Biological Chemistry 279:34, pages 36132-36141.
Crossref
Karim Kaabeche, Jérome Lemonnier, Sandrine Le Mée, Joseph Caverzasio & Pierre J. Marie. (2004) Cbl-mediated Degradation of Lyn and Fyn Induced by Constitutive Fibroblast Growth Factor Receptor-2 Activation Supports Osteoblast Differentiation. Journal of Biological Chemistry 279:35, pages 36259-36267.
Crossref
Lei Duan, Alagarsamy Lakku Reddi, Amiya Ghosh, Manjari Dimri & Hamid Band. (2004) The Cbl Family and Other Ubiquitin Ligases. Immunity 21:1, pages 7-17.
Crossref
Elena A Feshchenko, Evgeniya V Smirnova, Gayathri Swaminathan, Anjali M Teckchandani, Rachana Agrawal, Hamid Band, Xiaolong Zhang, Roland S Annan, Steven A Carr & Alexander Y Tsygankov. (2004) TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin. Oncogene 23:27, pages 4690-4706.
Crossref
Jian Zhang. (2004) Ubiquitin ligases in T cell activation and autoimmunity. Clinical Immunology 111:3, pages 234-240.
Crossref
S. Sigismund, S. Polo & P. P. Di Fiore. 2004. Signalling from Internalized Growth Factor Receptors. Signalling from Internalized Growth Factor Receptors 149 185 .
J.M. Auger, D. Best, D.C. Snell, J.I. Wilde & S.P. Watson. (2003) c-Cbl negatively regulates platelet activation by glycoprotein VI. Journal of Thrombosis and Haemostasis 1:11, pages 2419-2426.
Crossref
Erika Geimonen, Imelyn Fernandez, Irina N. Gavrilovskaya & Erich R. Mackow. (2003) Tyrosine Residues Direct the Ubiquitination and Degradation of the NY-1 Hantavirus G1 Cytoplasmic Tail. Journal of Virology 77:20, pages 10760-10868.
Crossref
Yuko Miura-Shimura, Lei Duan, Navin L. Rao, Alagarsamy L. Reddi, Hideki Shimura, Rob Rottapel, Brain J. Druker, Alexander Tsygankov, Vimla Band & Hamid Band. (2003) Cbl-mediated Ubiquitinylation and Negative Regulation of Vav. Journal of Biological Chemistry 278:40, pages 38495-38504.
Crossref
Shinkou Kyo, Kiyonao Sada, Xiujuan Qu, Koichiro Maeno, S. M. Shahjahan Miah, Keiko Kawauchi-Kamata & Hirohei Yamamura. (2003) Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in FcɛRI-mediated mast cell activation. Genes to Cells 8:10, pages 825-836.
Crossref
Lei Duan, Yuko Miura, Manjari Dimri, Biswanath Majumder, Ingrid L. Dodge, Alagarsamy L. Reddi, Amiya Ghosh, Norvin Fernandes, Pengcheng Zhou, Karen Mullane-Robinson, Navin Rao, Stephen Donoghue, Rick A. Rogers, David Bowtell, Mayumi Naramura, Hua Gu, Vimla Band & Hamid Band. (2003) Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis. Journal of Biological Chemistry 278:31, pages 28950-28960.
Crossref
Nathalie Niederberger, Kaisa Holmberg, S. Munir Alam, Wayne Sakati, Mayumi Naramura, Hua Gu & Nicholas R. J. Gascoigne. (2003) Allelic Exclusion of the TCR α-Chain Is an Active Process Requiring TCR-Mediated Signaling and c-Cbl. The Journal of Immunology 170:9, pages 4557-4563.
Crossref
Jing Bao, Gal Gur & Yosef Yarden. (2003) Src promotes destruction of c-Cbl: Implications for oncogenic synergy between Src and growth factor receptors. Proceedings of the National Academy of Sciences 100:5, pages 2438-2443.
Crossref
Wallace Y. Langdon. 2003. Handbook of Cell Signaling. Handbook of Cell Signaling 483 486 .
Eyleen L. K. Goh, Tao Zhu, Wan-Ying Leong & Peter E. Lobie. (2002) c-Cbl Is a Negative Regulator of GH-Stimulated STAT5-Mediated Transcription. Endocrinology 143:9, pages 3590-3603.
Crossref
Lin Wang, William A Rudert, Inna Loutaev, Vera Roginskaya & Seth J Corey. (2002) Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation. Oncogene 21:34, pages 5346-5355.
Crossref
Margaret Porter Scott, Francesca Zappacosta, Eun Young Kim, Roland S. Annan & W. Todd Miller. (2002) Identification of Novel SH3 Domain Ligands for the Src Family Kinase Hck. Journal of Biological Chemistry 277:31, pages 28238-28246.
Crossref
Frédérique Verdier, Taras Valovka, Alexander Zhyvoloup, Ludmila B. Drobot, Vladimir Buchman, Mike Waterfield & Ivan Gout. (2002) Ruk is ubiquitinated but not degraded by the proteasome. European Journal of Biochemistry 269:14, pages 3402-3408.
Crossref
Maddalena Panigada, Simona Porcellini, Eliane Barbier, Sonja Hoeflinger, Pierre-André Cazenave, Hua Gu, Hamid Band, Harald von Boehmer & Fabio Grassi. (2002) Constitutive Endocytosis and Degradation of the Pre-T Cell Receptor. Journal of Experimental Medicine 195:12, pages 1585-1597.
Crossref
Margaret C. Frame. (2002) Src in cancer: deregulation and consequences for cell behaviour. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1602:2, pages 114-130.
Crossref
Laurent Corsois, Brigitte Quatannens, Patrick Dumont, Marc Aumercier, Marie-Paule Defresne & Daniel C.L. Régnier. (2002) Association of a new c-Cbl related protein with the very first stages of apoptosis induction. Cancer Detection and Prevention 26:2, pages 93-104.
Crossref
André VeilletteSylvain LatourDominique Davidson. (2002) Negative Regulation of Immunoreceptor Signaling. Annual Review of Immunology 20:1, pages 669-707.
Crossref
Navin Rao, Sachiko Miyake, Alagarsamy Lakku Reddi, Patrice Douillard, Amiya K. Ghosh, Ingrid L. Dodge, Pengcheng Zhou, Norvin D. Fernandes & Hamid Band. (2002) Negative regulation of Lck by Cbl ubiquitin ligase. Proceedings of the National Academy of Sciences 99:6, pages 3794-3799.
Crossref
Christopher J Howlett & Stephen M Robbins. (2002) Membrane-anchored Cbl suppresses Hck protein-tyrosine kinase mediated cellular transformation. Oncogene 21:11, pages 1707-1716.
Crossref
Ibrahim Y. Hawash, Robert L. Geahlen, Marietta L. Harrison, Kamala P. Kesavan & Anthony I. Magee. (2002) The Lck SH3 Domain Negatively Regulates Localization to Lipid Rafts through an Interaction with c-Cbl. Journal of Biological Chemistry 277:7, pages 5683-5691.
Crossref
Frederic Bard, Urjeet Patel, Joan B. Levy, William C. Horne & Roland Baron. (2002) Molecular complexes that contain both c-Cbl and c-Src associate with Golgi membranes. European Journal of Cell Biology 81:1, pages 26-35.
Crossref
Archana SanjayWilliam C. HorneRoland Baron. (2001) The Cbl Family: Ubiquitin Ligases Regulating Signaling by Tyrosine Kinases. Science's STKE 2001:110.
Crossref
Sacha J. Holland, X. Charlene Liao, Marcy K. Mendenhall, Xiulan Zhou, Jorge Pardo, Peter Chu, Collin Spencer, Alan Fu, Ning Sheng, Peiwen Yu, Erlina Pali, Anup Nagin, Mary Shen, Simon Yu, Eva Chan, Xian Wu, Connie Li, Max Woisetschlager, Gregorio Aversa, Frank Kolbinger, Mark K. Bennett, Susan Molineaux, Ying Luo, Donald G. Payan, Helena S.Y. Mancebo & Jun Wu. (2001) Functional Cloning of Src-like Adapter Protein-2 (SLAP-2), a Novel Inhibitor of Antigen Receptor Signaling. Journal of Experimental Medicine 194:9, pages 1263-1276.
Crossref
Warren A Blesofsky, Kerri Mowen, Robert M Arduini, Darren P Baker, Maria A Murphy, David D L Bowtell & Michael David. (2001) Regulation of STAT protein synthesis by c-Cbl. Oncogene 20:50, pages 7326-7333.
Crossref
Alexander Y Tsygankov, Anjali M Teckchandani, Elena A Feshchenko & Gayathri Swaminathan. (2001) Beyond the RING: CBL proteins as multivalent adapters. Oncogene 20:44, pages 6382-6402.
Crossref
Masahiro Yokouchi, Takeshi Kondo, Archana Sanjay, Adam Houghton, Akihiko Yoshimura, Seturo Komiya, Hui Zhang & Roland Baron. (2001) Src-catalyzed Phosphorylation of c-Cbl Leads to the Interdependent Ubiquitination of Both Proteins. Journal of Biological Chemistry 276:37, pages 35185-35193.
Crossref
Jean-Ehrland Ricci, Valerie Lang, Fréderic Luciano, Nathalie Belhacene, Valerie Giordanengo, Frédérique Michel, Georges Bismuth & Patrick Auberger. (2001) An absolute requirement for Fyn in T cell receptor‐induced caspase activation and apoptosis. The FASEB Journal 15:10, pages 1777-1779.
Crossref
Seth A. Ettenberg, Alessandra Magnifico, Mauricio Cuello, Marion M. Nau, Yaffa R. Rubinstein, Yosef Yarden, Allan M. Weissman & Stan Lipkowitz. (2001) Cbl-b-dependent Coordinated Degradation of the Epidermal Growth Factor Receptor Signaling Complex. Journal of Biological Chemistry 276:29, pages 27677-27684.
Crossref
Xiao-Ling Li & Bret A. Hassel. (2001) INVOLVEMENT OF PROTEASOMES IN GENE INDUCTION BY INTERFERON AND DOUBLE-STRANDED RNA. Cytokine 14:5, pages 247-252.
Crossref
Connie Krawczyk & Josef M. Penninger. (2001) Molecular controls of antigen receptor clustering and autoimmunity. Trends in Cell Biology 11:5, pages 212-220.
Crossref
Christine B. F. Thien & Wallace Y. Langdon. (2001) Cbl: many adaptations to regulate protein tyrosine kinases. Nature Reviews Molecular Cell Biology 2:4, pages 294-307.
Crossref
Anjali M Teckchandani, Elena A Feshchenko & Alexander Y Tsygankov. (2001) c-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPases. Oncogene 20:14, pages 1739-1755.
Crossref
Rebecca D. ChernockRama P. CherlaRamesh K. Ganju. (2001) SHP2 and cbl participate in α-chemokine receptor CXCR4–mediated signaling pathways. Blood 97:3, pages 608-615.
Crossref
Vibeke Sundvold, Knut Martin Torgersen, Nicholas H. Post, Francesc Marti, Philip D. King, John Arne Røttingen, Anne Spurkland & Tor Lea. (2000) Cutting Edge: T Cell-Specific Adapter Protein Inhibits T Cell Activation by Modulating Lck Activity. The Journal of Immunology 165:6, pages 2927-2931.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.