Citations (82)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Stefan Gazdoiu, Kosj Yamoah, Kenneth Wu & Zhen-Qiang Pan. (2007) Human Cdc34 Employs Distinct Sites To Coordinate Attachment of Ubiquitin to a Substrate and Assembly of Polyubiquitin Chains. Molecular and Cellular Biology 27:20, pages 7041-7052.
Read now
Read now
Ana M. Gil-Bernabé, Francisco Romero, M. Cristina Limón-Mortés & María Tortolero. (2006) Protein Phosphatase 2A Stabilizes Human Securin, Whose Phosphorylated Forms Are Degraded via the SCF Ubiquitin Ligase. Molecular and Cellular Biology 26:11, pages 4017-4027.
Read now
Read now
Po-Yuan Ke & Zee-Fen Chang. (2004) Mitotic Degradation of Human Thymidine Kinase 1 Is Dependent on the Anaphase-Promoting Complex/Cyclosome–Cdh1-Mediated Pathway. Molecular and Cellular Biology 24:2, pages 514-526.
Read now
Read now
Binghui Li, Joseph C. Ruiz & Kristin T. Chun. (2002) CUL-4A Is Critical for Early Embryonic Development. Molecular and Cellular Biology 22:14, pages 4997-5005.
Read now
Read now
Articles from other publishers (78)
Yu Cao, Jing Zheng, Huayun Wan, Yuqiu Sun, Song Fu, Shanshan Liu, Baiyu He, Gaihong Cai, Yang Cao, Huanwei Huang, Qi Li, Yan Ma, She Chen, Fengchao Wang & Hui Jiang. (2023)
A mitochondrial
SCF‐FBXL4
ubiquitin
E3
ligase complex degrades
BNIP3
and
NIX
to restrain mitophagy and prevent mitochondrial disease
. The EMBO Journal.
Crossref
Crossref
Yuan Zhou, Runzhe Chen, Xiaofang Luo, Wei-Dong Zhang & Jiang-Jiang Qin. (2020) The E2 ubiquitin-conjugating enzyme UbcH5c: an emerging target in cancer and immune disorders. Drug Discovery Today 25:11, pages 1988-1997.
Crossref
Crossref
Spencer Hill, Kurt Reichermeier, Daniel C Scott, Lorena Samentar, Jasmin Coulombe-Huntington, Luisa Izzi, Xiaojing Tang, Rebeca Ibarra, Thierry Bertomeu, Annie Moradian, Michael J Sweredoski, Nora Caberoy, Brenda A Schulman, Frank Sicheri, Mike Tyers & Gary Kleiger. (2019) Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways. eLife 8.
Crossref
Crossref
Leyla FouaniZaklina KovacevicDes R. Richardson. (2019) Targeting Oncogenic Nuclear Factor Kappa B Signaling with Redox-Active Agents for Cancer Treatment. Antioxidants & Redox Signaling 30:8, pages 1096-1123.
Crossref
Crossref
Qiuju Chen, Dong Meng, Zhaoyu Gu, Wei Li, Hui Yuan, Xuwei Duan, Qing Yang, Yang Li & Tianzhong Li. (2018) SLFL Genes Participate in the Ubiquitination and Degradation Reaction of S-RNase in Self-compatible Peach. Frontiers in Plant Science 9.
Crossref
Crossref
Tomoaki Nagai, Sachiho Mukoyama, Harumi Kagiwada, Naoki Goshima & Kensaku Mizuno. (2018) Cullin-3-KCTD10-mediated CEP97 degradation promotes primary cilium formation. Journal of Cell Science.
Crossref
Crossref
Xiaofang Wang, Wenjuan Zhang, Zi Yan, Yupei Liang, Lihui Li, Xiaoli Yu, Yan Feng, Shen Fu, Yanmei Zhang, Hu Zhao, Jinha Yu, Lak Shin Jeong, Xiaomao Guo & Lijun Jia. (2016) Radiosensitization by the investigational NEDD8-activating enzyme inhibitor MLN4924 (pevonedistat) in hormone-resistant prostate cancer cells. Oncotarget 7:25, pages 38380-38391.
Crossref
Crossref
Danrui Cui, Xiufang Xiong & Yongchao Zhao. (2016) Cullin-RING ligases in regulation of autophagy. Cell Division 11:1.
Crossref
Crossref
Ammar Sukari, Irfana Muqbil, Ramzi M. Mohammad, Philip A. Philip & Asfar S. Azmi. (2016) F-BOX proteins in cancer cachexia and muscle wasting: Emerging regulators and therapeutic opportunities. Seminars in Cancer Biology 36, pages 95-104.
Crossref
Crossref
Xuesen Li, Noriko N. Yokoyama, Saiyang Zhang, Lina Ding, Hong-min Liu, Michael B. Lilly, Dan Mercola & Xiaolin Zi. (2015) Flavokawain A induces deNEDDylation and Skp2 degradation leading to inhibition of tumorigenesis and cancer progression in the TRAMP transgenic mouse model. Oncotarget 6:39, pages 41809-41824.
Crossref
Crossref
Abbas K. Samadi, Alan Bilsland, Alexandros G. Georgakilas, Amedeo Amedei, Amr Amin, Anupam Bishayee, Asfar S. Azmi, Bal L. Lokeshwar, Brendan Grue, Carolina Panis, Chandra S. Boosani, Deepak Poudyal, Diana M. Stafforini, Dipita Bhakta, Elena Niccolai, Gunjan Guha, H.P. Vasantha Rupasinghe, Hiromasa Fujii, Kanya Honoki, Kapil Mehta, Katia Aquilano, Leroy Lowe, Lorne J. Hofseth, Luigi Ricciardiello, Maria Rosa Ciriolo, Neetu Singh, Richard L. Whelan, Rupesh Chaturvedi, S. Salman Ashraf, H.M.C. Shantha Kumara, Somaira Nowsheen, Sulma I. Mohammed, W. Nicol Keith, William G. Helferich & Xujuan Yang. (2015) A multi-targeted approach to suppress tumor-promoting inflammation. Seminars in Cancer Biology 35, pages S151-S184.
Crossref
Crossref
Patricia RadaAna I. RojoAnika OffergeldGui Jie FengJuan P. Velasco-MartínJosé Manuel González-SanchoÁngela M. ValverdeTrevor DaleJavier RegaderaAntonio Cuadrado. (2015) WNT-3A Regulates an Axin1/NRF2 Complex That Regulates Antioxidant Metabolism in Hepatocytes. Antioxidants & Redox Signaling 22:7, pages 555-571.
Crossref
Crossref
Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin & Junjie Chen. (2015) Proteomic analyses reveal distinct chromatin‐associated and soluble transcription factor complexes. Molecular Systems Biology 11:1.
Crossref
Crossref
M Tan, H Li & Y Sun. (2013) Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis. Oncogene 33:44, pages 5211-5220.
Crossref
Crossref
Roberto Magliozzi, Jihoon Kim, Teck Yew Low, Albert J.R. Heck & Daniele Guardavaccaro. (2014) Degradation of Tiam1 by Casein Kinase 1 and the SCFβTrCP Ubiquitin Ligase Controls the Duration of mTOR-S6K Signaling. Journal of Biological Chemistry 289:40, pages 27400-27409.
Crossref
Crossref
Justin A Bosch, Taryn M Sumabat, Yassi Hafezi, Brett J Pellock, Kevin D Gandhi & Iswar K Hariharan. (2014) The Drosophila F-box protein Fbxl7 binds to the protocadherin Fat and regulates Dachs localization and Hippo signaling. eLife 3.
Crossref
Crossref
Hua Li, Mingjia Tan, Lijun Jia, Dongping Wei, Yongchao Zhao, Guoan Chen, Jie Xu, Lili Zhao, Dafydd Thomas, David G. Beer & Yi Sun. (2014) Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis. Journal of Clinical Investigation 124:2, pages 835-846.
Crossref
Crossref
Lucia Cordero-Espinoza & Thilo Hagen. (2013) Regulation of Cullin-RING ubiquitin ligase 1 by Spliceosome-associated protein 130 (SAP130). Biology Open 2:8, pages 838-844.
Crossref
Crossref
Chuan-Ming Xie, Wenyi Wei & Yi Sun. (2013) Role of SKP1-CUL1-F-Box-Protein (SCF) E3 Ubiquitin Ligases in Skin Cancer. Journal of Genetics and Genomics 40:3, pages 97-106.
Crossref
Crossref
Yi Sun & Hua Li. (2012) Functional characterization of SAG/RBX2/ROC2/RNF7, an antioxidant protein and an E3 ubiquitin ligase. Protein & Cell 4:2, pages 103-116.
Crossref
Crossref
Bastian Hoesel & Johannes A Schmid. (2013) The complexity of NF-κB signaling in inflammation and cancer. Molecular Cancer 12:1, pages 86.
Crossref
Crossref
Xinsong Xu, Malik Keshwani, Kathleen Meyer, Antonio Sarikas, Susan Taylor & Zhen-Qiang Pan. (2012) Identification of the Degradation Determinants of Insulin Receptor Substrate 1 for Signaling Cullin-RING E3 Ubiquitin Ligase 7-mediated Ubiquitination. Journal of Biological Chemistry 287:48, pages 40758-40766.
Crossref
Crossref
Y Zhao, X Xiong, L Jia & Y Sun. (2012) Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death & Disease 3:9, pages e386-e386.
Crossref
Crossref
Yongchao Zhao & Yi Sun. (2012) Targeting the mTOR-DEPTOR Pathway by CRL E3 Ubiquitin Ligases: Therapeutic Application. Neoplasia 14:5, pages 360-367.
Crossref
Crossref
Dong Yang, Mingjia Tan, Gongxian Wang & Yi Sun. (2012) The p21-Dependent Radiosensitization of Human Breast Cancer Cells by MLN4924, an Investigational Inhibitor of NEDD8 Activating Enzyme. PLoS ONE 7:3, pages e34079.
Crossref
Crossref
Dongping Wei, Hua Li, Jie Yu, Jonathan T. Sebolt, Lili Zhao, Theodore S. Lawrence, Peter G. Smith, Meredith A. Morgan & Yi Sun. (2012) Radiosensitization of Human Pancreatic Cancer Cells by MLN4924, an Investigational NEDD8-Activating Enzyme Inhibitor. Cancer Research 72:1, pages 282-293.
Crossref
Crossref
Mingjia Tan, Yongchao Zhao, Sun-Jung Kim, Margaret Liu, Lijun Jia, Thomas L. Saunders, Yuan Zhu & Yi Sun. (2011) SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation. Developmental Cell 21:6, pages 1062-1076.
Crossref
Crossref
Lijun Jia, Hua Li & Yi Sun. (2011) Induction of p21-Dependent Senescence by an NAE Inhibitor, MLN4924, as a Mechanism of Growth Suppression. Neoplasia 13:6, pages 561-569.
Crossref
Crossref
Céline Huber, Arnold Munnich & Valerie Cormier-Daire. (2011) The 3M syndrome. Best Practice & Research Clinical Endocrinology & Metabolism 25:1, pages 143-151.
Crossref
Crossref
Kenneth Wu, Jordan Kovacev & Zhen-Qiang Pan. (2010) Priming and Extending: A UbcH5/Cdc34 E2 Handoff Mechanism for Polyubiquitination on a SCF Substrate. Molecular Cell 37:6, pages 784-796.
Crossref
Crossref
Tomoyasu Isobe, Takayuki Hattori, Kyoko Kitagawa, Chiharu Uchida, Yojiro Kotake, Isao Kosugi, Toshiaki Oda & Masatoshi Kitagawa. (2009) Adenovirus E1A Inhibits SCFFbw7 Ubiquitin Ligase. Journal of Biological Chemistry 284:41, pages 27766-27779.
Crossref
Crossref
Mingjia TanShannon W. DavisThomas L. Saunders, Yuan Zhu & Yi Sun. (2009) RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27. Proceedings of the National Academy of Sciences 106:15, pages 6203-6208.
Crossref
Crossref
Suchithra Menon, Tomohiko Tsuge, Naoshi Dohmae, Koji Takio & Ning Wei. (2008) Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome. BMC Biochemistry 9:1.
Crossref
Crossref
Kosj Yamoah, Taiji Oashi, Antonio Sarikas, Stefan Gazdoiu, Roman Osman & Zhen-Qiang Pan. (2008) Autoinhibitory regulation of SCF-mediated ubiquitination by human cullin 1's C-terminal tail. Proceedings of the National Academy of Sciences 105:34, pages 12230-12235.
Crossref
Crossref
M. Cristina Limón-Mortés, Mar Mora-Santos, Águeda Espina, José A. Pintor-Toro, Antonio López-Román, María Tortolero & Francisco Romero. (2008) UV-induced degradation of securin is mediated by SKP1-CUL1-βTrCP E3 ubiquitin ligase. Journal of Cell Science 121:11, pages 1825-1831.
Crossref
Crossref
Adriana O. Manfiolli, Ana Leticia G.C. Maragno, Munira M.A. Baqui, Sami Yokoo, Felipe R. Teixeira, Eduardo B. Oliveira & Marcelo D. Gomes. (2008) FBXO25-associated Nuclear Domains: A Novel Subnuclear Structure. Molecular Biology of the Cell 19:5, pages 1848-1861.
Crossref
Crossref
Hongbin He, Qingyang Gu, Min Zheng, Daniel Normolle & Yi Sun. (2008) SAG/ROC2/RBX2 E3 ligase promotes UVB-induced skin hyperplasia, but not skin tumors, by simultaneously targeting c-Jun/AP-1 and p27. Carcinogenesis 29:4, pages 858-865.
Crossref
Crossref
Ron A.-J Chen, Grigory Ryzhakov, Samantha Cooray, Felix Randow & Geoffrey L Smith. (2008) Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14. PLoS Pathogens 4:2, pages e22.
Crossref
Crossref
Xiaoyun Wen, Karen M. Duus, Thomas D. Friedrich & Carlos M.C. de Noronha. (2007) The HIV1 Protein Vpr Acts to Promote G2 Cell Cycle Arrest by Engaging a DDB1 and Cullin4A-containing Ubiquitin Ligase Complex Using VprBP/DCAF1 as an Adaptor. Journal of Biological Chemistry 282:37, pages 27046-27057.
Crossref
Crossref
Laure Meyer, Bénédicte Deau, Hana Forejtníková, Dominique Duménil, Florence Margottin-Goguet, Catherine Lacombe, Patrick Mayeux & Frédérique Verdier. (2007) β-Trcp mediates ubiquitination and degradation of the erythropoietin receptor and controls cell proliferation. Blood 109:12, pages 5215-5222.
Crossref
Crossref
Gregory A Cope & Raymond J Deshaies. (2006) Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels. BMC Biochemistry 7:1.
Crossref
Crossref
Yi Sun. (2006) E3 Ubiquitin Ligases as Cancer Targets and Biomarkers. Neoplasia 8:8, pages 645-654.
Crossref
Crossref
Niels Mailand, Simon Bekker-Jensen, Jiri Bartek & Jiri Lukas. (2006) Destruction of Claspin by SCFβTrCP Restrains Chk1 Activation and Facilitates Recovery from Genotoxic Stress. Molecular Cell 23:3, pages 307-318.
Crossref
Crossref
Ashleigh Sartor, J.B. Kossoris, R. Wilcox, R. Shearer, A.E. Zeneberg, P. Zhao, I. Lazdins & Maria A. Burnatowska-Hledin. (2006) Truncated form of VACM-1/cul-5 with an extended 3′ untranslated region stimulates cell growth via a MAPK-dependent pathway. Biochemical and Biophysical Research Communications 343:4, pages 1086-1093.
Crossref
Crossref
Allan M. Gurtan, Patricia Stuckert & Alan D. D'Andrea. (2006) The WD40 Repeats of FANCL Are Required for Fanconi Anemia Core Complex Assembly. Journal of Biological Chemistry 281:16, pages 10896-10905.
Crossref
Crossref
Stefan Gazdoiu, Kosj Yamoah, Kenneth Wu, Carlos R. Escalante, Inger Tappin, Vladimir Bermudez, Aneel K. Aggarwal, Jerard Hurwitz & Zhen-Qiang Pan. (2005) Proximity-induced activation of human Cdc34 through heterologous dimerization. Proceedings of the National Academy of Sciences 102:42, pages 15053-15058.
Crossref
Crossref
Céline Huber, Dora Dias-Santagata, Anna Glaser, James O'Sullivan, Raja Brauner, Kenneth Wu, Xinsong Xu, Kerra Pearce, Rong Wang, Maria Luisa Giovannucci Uzielli, Nathalie Dagoneau, Wassim Chemaitilly, Andrea Superti-Furga, Heloisa Dos Santos, André Mégarbané, Gilles Morin, Gabriele Gillessen-Kaesbach, Raoul Hennekam, Ineke Van der Burgt, Graeme C M Black, Peter E Clayton, Andrew Read, Martine Le Merrer, Peter J Scambler, Arnold Munnich, Zhen-Qiang Pan, Robin Winter & Valérie Cormier-Daire. (2005) Identification of mutations in CUL7 in 3-M syndrome. Nature Genetics 37:10, pages 1119-1124.
Crossref
Crossref
Christina M. Ulane, Alex Kentsis, Cristian D. Cruz, Jean-Patrick Parisien, Kristi L. Schneider & Curt M. Horvath. (2005) Composition and Assembly of STAT-Targeting Ubiquitin Ligase Complexes: Paramyxovirus V Protein Carboxyl Terminus Is an Oligomerization Domain. Journal of Virology 79:16, pages 10180-10189.
Crossref
Crossref
R Kawaida, R Yamada, K Kobayashi, S Tokuhiro, A Suzuki, Y Kochi, X Chang, A Sekine, T Tsunoda, T Sawada, H Furukawa, Y Nakamura & K Yamamoto. (2005) CUL1, a component of E3 ubiquitin ligase, alters lymphocyte signal transduction with possible effect on rheumatoid arthritis. Genes & Immunity 6:3, pages 194-202.
Crossref
Crossref
Felicia Miller, Alex Kentsis, Roman Osman & Zhen-Qiang Pan. (2005) Inactivation of VHL by Tumorigenic Mutations That Disrupt Dynamic Coupling of the pVHL·Hypoxia-inducible Transcription Factor-1α Complex. Journal of Biological Chemistry 280:9, pages 7985-7996.
Crossref
Crossref
Nonggao He, Chengxin Li, Xiaoli Zhang, Tao Sheng, Sumin Chi, Kai Chen, Qian Wang, Roger Vertrees, Roberto Logrono & Jingwu Xie. (2005) Regulation of lung cancer cell growth and invasiveness by ?-TRCP. Molecular Carcinogenesis 42:1, pages 18-28.
Crossref
Crossref
Richard Crane, Angela Kloepfer & Joan V. Ruderman. (2004) Requirements for the destruction of human Aurora-A. Journal of Cell Science 117:25, pages 5975-5983.
Crossref
Crossref
Qin Yan, Takumi Kamura, Yong Cai, Jingji Jin, Mircea Ivan, Arcady Mushegian, Ronald C. Conaway & Joan Weliky Conaway. (2004) Identification of Elongin C and Skp1 Sequences That Determine Cullin Selection. Journal of Biological Chemistry 279:41, pages 43019-43026.
Crossref
Crossref
Wen-Liang Kuo, Crystal J. Duke, Mark K. Abe, Evan L. Kaplan, Suzana Gomes & Marsha Rich Rosner. (2004) ERK7 Expression and Kinase Activity Is Regulated by the Ubiquitin-Proteosome Pathway. Journal of Biological Chemistry 279:22, pages 23073-23081.
Crossref
Crossref
Zhen-Qiang Pan, Alex Kentsis, Dora C Dias, Kosj Yamoah & Kenneth Wu. (2004) Nedd8 on cullin: building an expressway to protein destruction. Oncogene 23:11, pages 1985-1997.
Crossref
Crossref
Ying Li, Stefan Gazdoiu, Zhen-Qiang Pan & Serge Y. Fuchs. (2004) Stability of Homologue of Slimb F-box Protein Is Regulated by Availability of Its Substrate. Journal of Biological Chemistry 279:12, pages 11074-11080.
Crossref
Crossref
James S. Foster, Romaine I. Fernando, Noriko Ishida, Keiichi I. Nakayama & Jay Wimalasena. (2003) Estrogens Down-regulate p27 in Breast Cancer Cells through Skp2 and through Nuclear Export Mediated by the ERK Pathway. Journal of Biological Chemistry 278:42, pages 41355-41366.
Crossref
Crossref
Kenneth Wu, Kosj Yamoah, Georgia Dolios, Tudeviin Gan-Erdene, Peilin Tan, Angus Chen, Chee-gun Lee, Ning Wei, Keith D. Wilkinson, Rong Wang & Zhen-Qiang Pan. (2003) DEN1 Is a Dual Function Protease Capable of Processing the C Terminus of Nedd8 and Deconjugating Hyper-neddylated CUL1. Journal of Biological Chemistry 278:31, pages 28882-28891.
Crossref
Crossref
L. Deng & Z. J. Chen. 2003. Nuclear Factor кB. Nuclear Factor кB
137
158
.
Dora C. Dias, Georgia Dolios, Rong Wang & Zhen-Qiang Pan. (2002) CUL7: A DOC domain-containing cullin selectively binds Skp1⋅Fbx29 to form an SCF-like complex. Proceedings of the National Academy of Sciences 99:26, pages 16601-16606.
Crossref
Crossref
Jianyu Zheng, Xiaoming Yang, Jennifer M. Harrell, Sophia Ryzhikov, Eun-Hee Shim, Karin Lykke-Andersen, Ning Wei, Hong Sun, Ryuji Kobayashi & Hui Zhang. (2002) CAND1 Binds to Unneddylated CUL1 and Regulates the Formation of SCF Ubiquitin E3 Ligase Complex. Molecular Cell 10:6, pages 1519-1526.
Crossref
Crossref
Gaochao Tian, Cynthia D. Sobotka-Briner, John Zysk, Xiaodong Liu, Cynthia Birr, Mark A. Sylvester, Philip D. Edwards, Clay D. Scott & Barry D. Greenberg. (2002) Linear Non-competitive Inhibition of Solubilized Human γ-Secretase by Pepstatin A Methylester, L685458, Sulfonamides, and Benzodiazepines. Journal of Biological Chemistry 277:35, pages 31499-31505.
Crossref
Crossref
Wen-Hui ShenYves ParmentierHanjo HellmannEsther LechnerAiwu DongJean MassonFabienne Granier, Loı̈c LepiniecMark EstellePascal Genschik. (2002)
Null Mutation of
AtCUL1
Causes Arrest in Early Embryogenesis in
Arabidopsis
. Molecular Biology of the Cell 13:6, pages 1916-1928.
Crossref
Crossref
Angus Chen, Frida E. Kleiman, James L. Manley, Toru Ouchi & Zhen-Qiang Pan. (2002) Autoubiquitination of the BRCA1·BARD1 RING Ubiquitin Ligase. Journal of Biological Chemistry 277:24, pages 22085-22092.
Crossref
Crossref
Esther Lechner, Pierre Goloubinoff, Pascal Genschik & Wen-Hui Shen. (2002) A gene trap Dissociation insertion line, associated with a RING-H2 finger gene, shows tissue specific and developmental regulated expression of the gene in Arabidopsis. Gene 290:1-2, pages 63-71.
Crossref
Crossref
Neehar Bhatia, Jason R Herter, Thomas J Slaga, Serge Y Fuchs & Vladimir S Spiegelman. (2002) Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-κB. Oncogene 21:10, pages 1501-1509.
Crossref
Crossref
Kenneth Wu, Angus Chen, Peilin Tan & Zhen-Qiang Pan. (2002) The Nedd8-conjugated ROC1-CUL1 Core Ubiquitin Ligase Utilizes Nedd8 Charged Surface Residues for Efficient Polyubiquitin Chain Assembly Catalyzed by Cdc34. Journal of Biological Chemistry 277:1, pages 516-527.
Crossref
Crossref
Takumi Kamura, Joan W. Conaway & Ronald C. Conaway. 2002. Protein Degradation in Health and Disease. Protein Degradation in Health and Disease
1
15
.
Xiaoai Chen, Yue Zhang, Leonille Douglas & Pengbo Zhou. (2001) UV-damaged DNA-binding Proteins Are Targets of CUL-4A-mediated Ubiquitination and Degradation. Journal of Biological Chemistry 276:51, pages 48175-48182.
Crossref
Crossref
Ottoline Leyser. (2001) Auxin signalling: the beginning, the middle and the end. Current Opinion in Plant Biology 4:5, pages 382-386.
Crossref
Crossref
Yi Sun, Mingjia Tan, Hangjun Duan & Manju Swaroop. (2001)
SAG/ROC/Rbx/Hrt
, a Zinc RING Finger Gene Family: Molecular Cloning, Biochemical Properties, and Biological Functions
. Antioxidants & Redox Signaling 3:4, pages 635-650.
Crossref
Crossref
Zhihong Lai, Katherine V. Ferry, Melody A. Diamond, Kevin E. Wee, Young B. Kim, Jianhong Ma, Tao Yang, Pamela A. Benfield, Robert A. Copeland & Kurt R. Auger. (2001) Human mdm2 Mediates Multiple Mono-ubiquitination of p53 by a Mechanism Requiring Enzyme Isomerization. Journal of Biological Chemistry 276:33, pages 31357-31367.
Crossref
Crossref
Lauren M DeSalle & Michele Pagano. (2001) Regulation of the G1 to S transition by the ubiquitin pathway. FEBS Letters 490:3, pages 179-189.
Crossref
Crossref
Sandro SantagataCarlos A. GomezCristina SobacchiFabio BozziMario AbinunSrdjan PasicPatricia CortesPaolo VezzoniAnna Villa. (2000)
N-terminal RAG1 frameshift mutations in Omenn's syndrome: Internal methionine usage leads to partial V(D)J recombination activity and reveals a fundamental role
in vivo
for the N-terminal domains
. Proceedings of the National Academy of Sciences 97:26, pages 14572-14577.
Crossref
Crossref
Kenneth Wu, Angus Chen & Zhen-Qiang Pan. (2000) Conjugation of Nedd8 to CUL1 Enhances the Ability of the ROC1-CUL1 Complex to Promote Ubiquitin Polymerization. Journal of Biological Chemistry 275:41, pages 32317-32324.
Crossref
Crossref
Manju Swaroop, Yixin Wang, Paul Miller, Hangjun Duan, Tim Jatkoe, Steven J Madore & Yi Sun. (2000) Yeast homolog of human SAG/ROC2/Rbx2/Hrt2 is essential for cell growth, but not for germination: chip profiling implicates its role in cell cycle regulation. Oncogene 19:24, pages 2855-2866.
Crossref
Crossref
Thomas Buschmann, Serge Y Fuchs, Chee-Gun Lee, Zhen-Qiang Pan & Ze'ev Ronai. (2000) SUMO-1 Modification of Mdm2 Prevents Its Self-Ubiquitination and Increases Mdm2 Ability to Ubiquitinate p53. Cell 101:7, pages 753-762.
Crossref
Crossref
Angus Chen, Kenneth Wu, Serge Y. Fuchs, Peilin Tan, Carlos Gomez & Zhen-Qiang Pan. (2000) The Conserved RING-H2 Finger of ROC1 Is Required for Ubiquitin Ligation. Journal of Biological Chemistry 275:20, pages 15432-15439.
Crossref
Crossref