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Molecular and Cellular Biology Volume 20, 2000 - Issue 7
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Gene Expression

Transcription-Coupled Translation Control of AML1/RUNX1 Is Mediated by Cap- and Internal Ribosome Entry Site-Dependent Mechanisms

Amir Pozner1 Department of Molecular Genetics, Weizmann Institute of Science, Rehovot76000
,
Dalia Goldenberg1 Department of Molecular Genetics, Weizmann Institute of Science, Rehovot76000
,
Varda Negreanu1 Department of Molecular Genetics, Weizmann Institute of Science, Rehovot76000
,
Shu-Yun Le2 Laboratory of Experimental and Computational Biology, DBS, National Cancer Institute, Frederick, Maryland21702
,
Orna Elroy-Stein3 Department of Cell Research and Immunology, Tel Aviv University, Tel Aviv, Israel
,
Ditsa Levanon1 Department of Molecular Genetics, Weizmann Institute of Science, Rehovot76000
&
Yoram Groner1 Department of Molecular Genetics, Weizmann Institute of Science, Rehovot76000Correspondence[email protected]
 show all
Pages 2297-2307 | Received 20 Jul 1999, Accepted 07 Dec 1999, Published online: 27 Mar 2023

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Xichuan Li, Zhenzhen Lin, Hao Wang, Dan Zhao, Xing Xu, Yiliang Wei, Xiaoting Li, Xiaobo Li, Yougui Xiang, Lance S. Terada & Zhe Liu. (2018) Heritable, Allele-Specific Chromosomal Looping between Tandem Promoters Specifies Promoter Usage of SHC1. Molecular and Cellular Biology 38:9.
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Christos Vaklavas, Zheng Meng, Hyoungsoo Choi, William E Grizzle, Kurt R Zinn & Scott W Blume. (2015) Small molecule inhibitors of IRES-mediated translation. Cancer Biology & Therapy 16:10, pages 1471-1485.
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Oded Suad, Eran Eyal, Immanuel Blumenzweig, Naama Kessler, Ditsa Levanon, Yoram Groner & Zippora Shakked. (2007) RUN-CBFβ Interaction in C. elegans: Computational Prediction and Experimental Verification. Journal of Biomolecular Structure and Dynamics 24:4, pages 343-357.
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Joëlle Michaud, Hamish S. Scott & Robert Escher. (2003) AML1 Interconnected Pathways of Leukemogenesis. Cancer Investigation 21:1, pages 105-136.
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Marilyn Kozak. (2001) New Ways of Initiating Translation in Eukaryotes?. Molecular and Cellular Biology 21:6, pages 1899-1907.
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Sebastian Nieke, Nighat Yasmin, Kiyokazu Kakugawa, Tomomasa Yokomizo, Sawako Muroi & Ichiro Taniuchi. (2017) Unique N-terminal sequences in two Runx1 isoforms are dispensable for Runx1 function. BMC Developmental Biology 17:1.
Crossref
Jennifer J. VanOudenhove, Ricardo Medina, Prachi N. Ghule, Jane B. Lian, Janet L. Stein, Sayyed K. Zaidi & Gary S. Stein. (2017) Precocious Phenotypic Transcription-Factor Expression During Early Development. Journal of Cellular Biochemistry 118:5, pages 953-958.
Crossref
Marella de Bruijn & Elaine Dzierzak. (2017) Runx transcription factors in the development and function of the definitive hematopoietic system. Blood 129:15, pages 2061-2069.
Crossref
Constanze Bonifer, Elena Levantini, Valerie Kouskoff & Georges Lacaud. 2017. RUNX Proteins in Development and Cancer. RUNX Proteins in Development and Cancer 65 81 .
Amanda D. Yzaguirre, Marella F. T. R. de Bruijn & Nancy A. Speck. 2017. RUNX Proteins in Development and Cancer. RUNX Proteins in Development and Cancer 47 64 .
Xi Wang, Jingyi Hou, Claudia Quedenau & Wei Chen. (2016) Pervasive isoform‐specific translational regulation via alternative transcription start sites in mammals. Molecular Systems Biology 12:7.
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Crossref
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Crossref
J. Tober, M.W. Maijenburg & N.A. Speck. 2016. Hematopoiesis. Hematopoiesis 113 162 .
Emilie Horvilleur, Lindsay A. Wilson, Amandine Bastide, David Piñeiro, Tuija A. A. Pöyry & Anne E. Willis. (2015) Cap-Independent Translation in Hematological Malignancies. Frontiers in Oncology 5.
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Crossref
Won Fen Wong, Kazuyoshi Kohu, Takeshi Nagashima, Ryo Funayama, Mitsuyo Matsumoto, Elaheh Movahed, Grace Min Yi Tan, Tee Cian Yeow, Chung Yeng Looi, Mineo Kurokawa, Motomi Osato, Kazuhiko Igarashi, Keiko Nakayama & Masanobu Satake. (2015) The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4+ T lymphocytes. Molecular Immunology 68:2, pages 223-233.
Crossref
Takashi Ebihara, Christina Song, Stacy H Ryu, Beatrice Plougastel-Douglas, Liping Yang, Ditsa Levanon, Yoram Groner, Michael D Bern, Thaddeus S Stappenbeck, Marco Colonna, Takeshi Egawa & Wayne M Yokoyama. (2015) Runx3 specifies lineage commitment of innate lymphoid cells. Nature Immunology 16:11, pages 1124-1133.
Crossref
Bin Lu, Xueqin Sun, Yuxuan Chen, Qi Jin, Qin Liang, Shangqin Liu, Yamu Li, Yan Zhou, Wenxin Li & Zan Huang. (2014) Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation. Cellular and Molecular Life Sciences 72:4, pages 821-832.
Crossref
Won Fen Wong, Chung Yeng Looi, Shunsuke Kon, Elaheh Movahed, Tomo Funaki, Li Yen Chang, Masanobu Satake & Kazuyoshi Kohu. (2014) T-cell receptor signaling induces proximal Runx1 transactivation via a calcineurin-NFAT pathway . European Journal of Immunology 44:3, pages 894-904.
Crossref
Judith Marsman, Adam C. O'Neill, Betty Rui-Yun Kao, Jenny M. Rhodes, Michael Meier, Jisha Antony, Maren Mönnich & Julia A. Horsfield. (2014) Cohesin and CTCF differentially regulate spatiotemporal runx1 expression during zebrafish development. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1839:1, pages 50-61.
Crossref
Godfrey Grech, Joel Pollacco, Mark Portelli, Keith Sacco, Shawn Baldacchino, Justine Grixti & Christian Saliba. (2013) Expression of different functional isoforms in haematopoiesis. International Journal of Hematology 99:1, pages 4-11.
Crossref
Adam C. Wilkinson & Berthold Göttgens. 2013. Transcriptional and Translational Regulation of Stem Cells. Transcriptional and Translational Regulation of Stem Cells 187 212 .
Takehito Sato, Tomoki Chiba, Shin-ichiro Ohno, Chiharu Sato, Tatsuya Sugoh, Keiko Miyashita, Hisako Akatsuka, Katsuto Hozumi, Yoshinori Okada, Yumi Iida, Akira Akatsuka, Yasutoshi Agata, Marin Chiba, Kazuyoshi Kohu, Masanobu Satake, Hideyuki Tanabe, Hideyuki Saya & Sonoko Habu. (2012) Reciprocal Control of G1-Phase Progression Is Required for Th-POK/Runx3–Mediated CD4/8 Thymocyte Cell Fate Decision. The Journal of Immunology 189:9, pages 4426-4436.
Crossref
E. N. Markova, N. V. Petrova, S. V. Razin & O. L. Kantidze. (2012) Transcription factor RUNX1. Molecular Biology 46:6, pages 755-767.
Crossref
Shuping Li & Guo-Fu Hu. (2012) Emerging role of angiogenin in stress response and cell survival under adverse conditions. Journal of Cellular Physiology 227:7, pages 2822-2826.
Crossref
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Crossref
Nicole I. zur Nieden. 2011. Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases. Embryonic Stem Cell Therapy for Osteo-Degenerative Diseases 1 30 .
Akiko Nagamachi, Phyo Wai Htun, Feng Ma, Kazuko Miyazaki, Norimasa Yamasaki, Masamoto Kanno, Toshiya Inaba, Zen-ichiro Honda, Tsukasa Okuda, Hideaki Oda, Kohichiro Tsuji & Hiroaki Honda. (2010) A 5′ untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model. Developmental Biology 345:2, pages 226-236.
Crossref
Alura Riley, Lindsay E. Jordan & Martin Holcik. (2010) Distinct 5′ UTRs regulate XIAP expression under normal growth conditions and during cellular stress. Nucleic Acids Research 38:14, pages 4665-4674.
Crossref
Karen Rae Bone, Yaron Gruper, Dalia Goldenberg, Ditsa Levanon & Yoram Groner. (2010) Translation regulation of Runx3. Blood Cells, Molecules, and Diseases 45:2, pages 112-116.
Crossref
Thomas BeeGemma SwiersSawako Muroi, Amir Pozner, Wade NottinghamAna Cristina SantosPik-Shan LiIchiro Taniuchi & Marella F. T. R. de Bruijn. (2010) Nonredundant roles for Runx1 alternative promoters reflect their activity at discrete stages of developmental hematopoiesis. Blood 115:15, pages 3042-3050.
Crossref
Patrycja Sroczynska, Christophe Lancrin, Valerie Kouskoff & Georges Lacaud. (2009) The differential activities of Runx1 promoters define milestones during embryonic hematopoiesis. Blood 114:26, pages 5279-5289.
Crossref
Caroline Conte, Nadera Ainaoui, Aurélie Delluc-Clavières, Marie P. Khoury, Rania Azar, Françoise Pujol, Yvan Martineau, Stéphane Pyronnet & Anne-Catherine Prats. (2009) Fibroblast growth factor 1 induced during myogenesis by a transcription–translation coupling mechanism. Nucleic Acids Research 37:16, pages 5267-5278.
Crossref
Gary M. Wildey & Philip H. Howe. (2009) Runx1 Is a Co-activator with FOXO3 to Mediate Transforming Growth Factor β (TGFβ)-induced Bim Transcription in Hepatic Cells. Journal of Biological Chemistry 284:30, pages 20227-20239.
Crossref
Thomas Bee, Kate Liddiard, Gemma Swiers, Sorrel R.B. Bickley, Chris S. Vink, Andrew Jarratt, Jim R. Hughes, Alexander Medvinsky & Marella F.T.R. de Bruijn. (2009) Alternative Runx1 promoter usage in mouse developmental hematopoiesis. Blood Cells, Molecules, and Diseases 43:1, pages 35-42.
Crossref
Enid Yi Ni Lam, Jackie Y. M. Chau, Maggie L. Kalev-Zylinska, Timothy M. Fountaine, R. Scott Mead, Christopher J. Hall, Philip S. Crosier, Kathryn E. Crosier & Maria Vega Flores. (2009) Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors. Blood 113:6, pages 1241-1249.
Crossref
Oren Ben-Ami, Niv Pencovich, Joseph Lotem, Ditsa Levanon & Yoram Groner. (2009) A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis. Proceedings of the National Academy of Sciences 106:1, pages 238-243.
Crossref
Leslie J. Marshall, Amy C. Moore, Misao Ohki, Issay Kitabayashi, David Patterson & David A. Ornelles. (2008) RUNX1 Permits E4orf6-Directed Nuclear Localization of the Adenovirus E1B-55K Protein and Associates with Centers of Viral DNA and RNA Synthesis. Journal of Virology 82:13, pages 6395-6408.
Crossref
Ramana V. Davuluri, Yutaka Suzuki, Sumio Sugano, Christoph Plass & Tim H.-M. Huang. (2008) The functional consequences of alternative promoter use in mammalian genomes. Trends in Genetics 24:4, pages 167-177.
Crossref
Shin-ichiro Ohno, Takehito Sato, Kazuyoshi Kohu, Kazuyoshi Takeda, Ko Okumura, Masanobu Satake & Sonoko Habu. (2008) Runx proteins are involved in regulation of CD122, Ly49 family and IFN-γ expression during NK cell differentiation. International Immunology 20:1, pages 71-79.
Crossref
Amir Pozner, Joseph Lotem, Cuiying Xiao, Dalia Goldenberg, Ori Brenner, Varda Negreanu, Ditsa Levanon & Yoram Groner. (2007) Developmentally regulated promoter-switch transcriptionally controls Runx1function during embryonic hematopoiesis. BMC Developmental Biology 7:1.
Crossref
H Kayed, X Jiang, S Keleg, R Jesnowski, T Giese, M R Berger, I Esposito, M Löhr, H Friess & J Kleeff. (2007) Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer. British Journal of Cancer 97:8, pages 1106-1115.
Crossref
Frédéric Marmigère & Patrik Ernfors. (2007) Specification and connectivity of neuronal subtypes in the sensory lineage. Nature Reviews Neuroscience 8:2, pages 114-127.
Crossref
Stephen D. Baird, Marcel Turcotte, Robert G. Korneluk & Martin Holcik. (2006) Searching for IRES. RNA 12:10, pages 1755-1785.
Crossref
Yang Zong, Sheng Zhou, Soghra Fatima & Brian P. Sorrentino. (2006) Expression of Mouse Abcg2 mRNA during Hematopoiesis Is Regulated by Alternative Use of Multiple Leader Exons and Promoters. Journal of Biological Chemistry 281:40, pages 29625-29632.
Crossref
Hideyo HiraiIgor M SamokhvalovTetsuhiro FujimotoSatomi NishikawaJiro ImanishiShin-Ichi Nishikawa. (2005) Involvement of Runx1 in the down-regulation of fetal liver kinase-1 expression during transition of endothelial cells to hematopoietic cells. Blood 106:6, pages 1948-1955.
Crossref
Pedro Miura, Jennifer Thompson, Joe V. Chakkalakal, Martin Holcik & Bernard J. Jasmin. (2005) The Utrophin A 5′-Untranslated Region Confers Internal Ribosome Entry Site-mediated Translational Control during Regeneration of Skeletal Muscle Fibers. Journal of Biological Chemistry 280:38, pages 32997-33005.
Crossref
Franck P. Dupuy, Enguerran Mouly, Mariana Mesel-Lemoine, Céline Morel, Julien Abriol, Mustapha Cherai, Claude Baillou, Didier Nègre, François-Loïc Cosset, David Klatzmann & François M. Lemoine. (2005) Lentiviral transduction of human hematopoietic cells by HIV-1- and SIV-based vectors containing a bicistronic cassette driven by various internal promoters. The Journal of Gene Medicine 7:9, pages 1158-1171.
Crossref
Ching-Ping Tseng, Pam Chang, Chien-Ling Huang, Ju-Chien Cheng & Shy-Shin Chang. (2005) Autocrine signaling of platelet-derived growth factor regulates disabled-2 expression during megakaryocytic differentiation of K562 cells. FEBS Letters 579:20, pages 4395-4401.
Crossref
P. W. Vanderklish & G. M. Edelman. (2005) Differential translation and fragile X syndrome. Genes, Brain and Behavior 4:6, pages 360-384.
Crossref
Sally A. Mitchell, Keith A. Spriggs, Martin Bushell, Joanne R. Evans, Mark Stoneley, John P.C. Le Quesne, Ruth V. Spriggs & Anne E. Willis. (2005) Identification of a motif that mediates polypyrimidine tract-binding protein-dependent internal ribosome entry. Genes & Development 19:13, pages 1556-1571.
Crossref
Michael Stock & Florian Otto. (2005) Control of RUNX2 isoform expression: The role of promoters and enhancers. Journal of Cellular Biochemistry 95:3, pages 506-517.
Crossref
Mario Galindo, Jitesh Pratap, Daniel W. Young, Hayk Hovhannisyan, Hee-Jeong Im, Je-Yong Choi, Jane B. Lian, Janet L. Stein, Gary S. Stein & Andre J. van Wijnen. (2005) The Bone-specific Expression of Runx2 Oscillates during the Cell Cycle to Support a G1-related Antiproliferative Function in Osteoblasts. Journal of Biological Chemistry 280:21, pages 20274-20285.
Crossref
H. P. Liu, A. M. Thompson & K. F. Macleod. (2005) A novel form of pRb expressed during normal myelopoiesis and in tumour-associated macrophages. Cell Proliferation 38:1, pages 13-24.
Crossref
Chouhei Sakakura, Akeo Hagiwara, Koji Miyagawa, Susumu Nakashima, Tetsuji Yoshikawa, Shuichi Kin, Yuenn Nakase, Kosei Ito, Hisakazu Yamagishi, Shujiro Yazumi, Tsutomu Chiba & Yoshiaki Ito. (2005) Frequent downregulation of the runt domain transcription factorsRUNX1,RUNX3 and their cofactorCBFB in gastric cancer. International Journal of Cancer 113:2, pages 221-228.
Crossref
Marat V. Khodoun, Tatyana Orekhova, Crystal Potter, Suzanne Morris & Fred D. Finkelman. (2004) Basophils Initiate IL-4 Production during a Memory T-dependent Response. Journal of Experimental Medicine 200:7, pages 857-870.
Crossref
Marieke Joosten, Montserrat Blázquez-Domingo, Fokke Lindeboom, Florence Boulmé, Antoinette Van Hoven-Beijen, Bianca Habermann, Bob Löwenberg, Hartmut Beug, Ernst W. Müllner, Ruud Delwel & Marieke Von Lindern. (2004) Translational Control of Putative Protooncogene Nm23-M2 by Cytokines via Phosphoinositide 3-Kinase Signaling. Journal of Biological Chemistry 279:37, pages 38169-38176.
Crossref
Marella FTR de Bruijn & Nancy A Speck. (2004) Core-binding factors in hematopoiesis and immune function. Oncogene 23:24, pages 4238-4248.
Crossref
Ditsa Levanon & Yoram Groner. (2004) Structure and regulated expression of mammalian RUNX genes. Oncogene 23:24, pages 4211-4219.
Crossref
Ewan R Cameron & James C Neil. (2004) The Runx genes: lineage-specific oncogenes and tumor suppressors. Oncogene 23:24, pages 4308-4314.
Crossref
Shuo Chen, Natalyia Inozentseva-Clayton, Juan Dong, Ting Ting Gu & Mary MacDougall. (2004) Binding of two nuclear factors to a novel silencer element in human dentin matrix protein 1 (DMP1) promoter regulates the cell type-specific DMP1 gene expression. Journal of Cellular Biochemistry 92:2, pages 332-349.
Crossref
Vinagolu K Rajasekhar & Eric C Holland. (2004) Postgenomic global analysis of translational control induced by oncogenic signaling. Oncogene 23:18, pages 3248-3264.
Crossref
Trista E. North, Terryl Stacy, Christina J. Matheny, Nancy A. Speck & Marella F.T.R. de Bruijn. (2008) Runx1 Is Expressed in Adult Mouse Hematopoietic Stem Cells and Differentiating Myeloid and Lymphoid Cells, But Not in Maturing Erythroid Cells. STEM CELLS 22:2, pages 158-168.
Crossref
Ruibao Ren. (2004) Modeling the dosage effect of oncogenes in leukemogenesis. Current Opinion in Hematology 11:1, pages 25-34.
Crossref
Eilon Woolf, Cuiying Xiao, Ofer Fainaru, Joseph Lotem, Dalia Rosen, Varda Negreanu, Yael Bernstein, Dalia Goldenberg, Ori Brenner, Gideon Berke, Ditsa Levanon & Yoram Groner. (2003) Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis. Proceedings of the National Academy of Sciences 100:13, pages 7731-7736.
Crossref
Ditsa Levanon, Ori Brenner, Florian Otto & Yoram Groner. (2003) Runx3 knockouts and stomach cancer . EMBO reports 4:6, pages 560-564.
Crossref
Ewan R Cameron, Karen Blyth, Linda Hanlon, Anna Kilbey, Nancy Mackay, Monica Stewart, Anne Terry, Francois Vaillant, Sandy Wotton & James C Neil. (2003) The Runx genes as dominant oncogenes. Blood Cells, Molecules, and Diseases 30:2, pages 194-200.
Crossref
Ditsa Levanon, Gustavo Glusman, David Bettoun, Edna Ben-Asher, Varda Negreanu, Yael Bernstein, Catherine Harris-Cerruti, Ori Brenner, Raya Eilam, Joseph Lotem, Ofer Fainaru, Dalia Goldenberg, Amir Pozner, Eilon Woolf, Cuiying Xiao, Merav Yarmus & Yoram Groner. (2003) Phylogenesis and regulated expression of the RUNT domain transcription factors RUNX1 and RUNX3. Blood Cells, Molecules, and Diseases 30:2, pages 161-163.
Crossref
Zhou-Sheng Xiao, Leigh G. Simpson & L. Darryl Quarles. (2003) IRES-dependent translational control ofCbfa1/Runx2 expression. Journal of Cellular Biochemistry 88:3, pages 493-505.
Crossref
Deborah Bartfeld, Linda Shimon, Graeme C. Couture, Dov Rabinovich, Felix Frolow, Ditsa Levanon, Yoram Groner & Zippora Shakked. (2002) DNA Recognition by the RUNX1 Transcription Factor Is Mediated by an Allosteric Transition in the RUNT Domain and by DNA Bending. Structure 10:10, pages 1395-1407.
Crossref
Monica Stewart, Nancy MacKay, Ewan R. Cameron & James C. Neil. (2002) The Common Retroviral Insertion Locus Dsi1 Maps 30 Kilobases Upstream of the P1 Promoter of the Murine Runx3 / Cbfa3 / Aml2 Gene . Journal of Virology 76:9, pages 4364-4369.
Crossref
Ditsa Levanon, Ori Brenner, Varda Negreanu, David Bettoun, Eilon Woolf, Raya Eilam, Joseph Lotem, Uri Gat, Florian Otto, Nancy Speck & Yoram Groner. (2001) Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis. Mechanisms of Development 109:2, pages 413-417.
Crossref
Jonathan D Licht. (2001) AML1 and the AML1-ETO fusion protein in the pathogenesis of t(8;21) AML. Oncogene 20:40, pages 5660-5679.
Crossref
Chaitali Banerjee, Amjad Javed, Je-Yong Choi, Jack Green, Vicki Rosen, André J. van Wijnen, Janet L. Stein, Jane B. Lian & Gary S. Stein. (2001) Differential Regulation of the Two Principal Runx2/Cbfa1 N-Terminal Isoforms in Response to Bone Morphogenetic Protein-2 during Development of the Osteoblast Phenotype. Endocrinology 142:9, pages 4026-4039.
Crossref
Christopher U.T. Hellen & Peter Sarnow. (2001) Internal ribosome entry sites in eukaryotic mRNA molecules. Genes & Development 15:13, pages 1593-1612.
Crossref
Catherine L Jopling & Anne E Willis. (2001) N-myc translation is initiated via an internal ribosome entry segment that displays enhanced activity in neuronal cells. Oncogene 20:21, pages 2664-2670.
Crossref
Stéphane Giraud, Anna Greco, Marijke Brink, Jean-Jacques Diaz & Patrick Delafontaine. (2001) Translation Initiation of the Insulin-like Growth Factor I Receptor mRNA Is Mediated by an Internal Ribosome Entry Site. Journal of Biological Chemistry 276:8, pages 5668-5675.
Crossref
Ditsa Levanon, Gustavo Glusman, Thorsten Bangsow, Edna Ben-Asher, Dean A Male, Nili Avidan, Carmen Bangsow, Masahira Hattori, Todd D Taylor, Stefan Taudien, Karin Blechschmidt, Nobuyoshi Shimizu, Andre Rosenthal, Yoshiyuki Sakaki, Doron Lancet & Yoram Groner. (2001) Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1. Gene 262:1-2, pages 23-33.
Crossref
Simon J. Morley. 2001. Signaling Pathways for Translation. Signaling Pathways for Translation 1 37 .
Martin Holcik, Nahum Sonenberg & Robert G. Korneluk. (2000) Internal ribosome initiation of translation and the control of cell death. Trends in Genetics 16:10, pages 469-473.
Crossref
John C Wheeler, Katsuya Shigesada, J Peter Gergen & Yoshiaki Ito. (2000) Mechanisms of transcriptional regulation by Runt domain proteins. Seminars in Cell & Developmental Biology 11:5, pages 369-375.
Crossref

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