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Jing Xu & Qichun Wei. (2012) Use of a peptide enhancing the ability of radiation therapy to kill cancer cells: a patent evaluation of WO2012016918. Expert Opinion on Therapeutic Patents 22:12, pages 1485-1487.
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Elena Sacco, Michela Spinelli & Marco Vanoni. (2012) Approaches to Ras signaling modulation and treatment of Ras-dependent disorders: a patent review (2007 – present). Expert Opinion on Therapeutic Patents 22:11, pages 1263-1287.
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Hadi Khalil, Nieves Peltzer, Joël Walicki, Jiang-Yan Yang, Gilles Dubuis, Noémie Gardiol, Werner Held, Paul Bigliardi, Benjamin Marsland, Lucas Liaudet & Christian Widmann. (2012) Caspase-3 Protects Stressed Organs against Cell Death. Molecular and Cellular Biology 32:22, pages 4523-4533.
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Jiang-Yan Yang, David Michod, Joël Walicki, Brona M. Murphy, Shailaja Kasibhatla, Seamus J. Martin & Christian Widmann. (2004) Partial Cleavage of RasGAP by Caspases Is Required for Cell Survival in Mild Stress Conditions. Molecular and Cellular Biology 24:23, pages 10425-10436.
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Joana Furtado Milão, Luca Love, George Gourgi, Lukas Derhaschnig, J. Peter Svensson, Anders Sönnerborg & Robert van Domselaar. (2022) Natural killer cells induce HIV-1 latency reversal after treatment with pan-caspase inhibitors. Frontiers in Immunology 13.
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Jinpeng Liu, Huixia Wei, Zhaohui Yang, Yixian Hao, Guimin Wang, Tuling Li, Ting Yu, Huiping Liao, Bo Bao, Qiuxin Wu, Hongsheng Bi & Dadong Guo. (2022) Enhanced Apoptosis in Choroidal Tissues in Lens-Induced Myopia Guinea Pigs by Activating the RASA1 Signaling Pathway. Investigative Opthalmology & Visual Science 63:11, pages 5.
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Gabriel Kreider-Letterman, Nicole M. Carr & Rafael Garcia-Mata. (2022) Fixing the GAP: The role of RhoGAPs in cancer. European Journal of Cell Biology 101:2, pages 151209.
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Shanshan Yao, Jiulin Chan, Yue Xu, Shimei Wu & Linlin Zhang. (2022) Divergences of the RLR Gene Families across Lophotrochozoans: Domain Grafting, Exon–Intron Structure, Expression, and Positive Selection. International Journal of Molecular Sciences 23:7, pages 3415.
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Charis Putinski & Lynn A. Megeney. 2022. Biochemistry of Apoptosis and Autophagy. Biochemistry of Apoptosis and Autophagy
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María del Carmen Conde-Rubio, Roman Mylonas & Christian Widmann. (2021) The proteolytic landscape of cells exposed to non-lethal stresses is shaped by executioner caspases. Cell Death Discovery 7:1.
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Eli Arama, Luis Alberto Baena‐Lopez & Howard O. Fearnhead. (2020) Non‐lethal message from the Holy Land: The first international conference on nonapoptotic roles of apoptotic proteins. The FEBS Journal 288:7, pages 2166-2183.
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Junfang Yan, Yi Xie, Jing Si, Lu Gan, Hongyan Li, Chao Sun, Cuixia Di, Jinhua Zhang, Guomin Huang, Xuetian Zhang & Hong Zhang. (2021) Crosstalk of the Caspase Family and Mammalian Target of Rapamycin Signaling. International Journal of Molecular Sciences 22:2, pages 817.
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Yan Cui, Susann Groth, Scott Troutman, Annemarie Carlstedt, Tobias Sperka, Lars Björn Riecken, Joseph L. Kissil, Hongchuan Jin & Helen Morrison. (2019) The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling. Oncogene 38:36, pages 6370-6381.
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Djuro Kosanovic, Simon Maximilian Platzek, Aleksandar Petrovic, Akylbek Sydykov, Abdirashit Maripov, Argen Mamazhakypov, Meerim Sartmyrzaeva, Kubatbek Muratali Uulu, Meerim Cholponbaeva, Aidana Toktosunova, Nazgul Omurzakova, Melis Duishobaev, Christina Vroom, Oleg Pak, Norbert Weissmann, Hossein Ardeschir Ghofrani, Akpay Sarybaev & Ralph Theo Schermuly. (2019) Circulating Apoptotic Signals During Acute and Chronic Exposure to High Altitude in Kyrgyz Population. Frontiers in Physiology 10.
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Charis Putinski, Mohammad Abdul‐Ghani, Steve Brunette, Patrick G. Burgon & Lynn A. Megeney. (2018) Caspase Cleavage of Gelsolin Is an Inductive Cue for Pathologic Cardiac Hypertrophy. Journal of the American Heart Association 7:23.
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Güliz Vanli, Christine Sempoux & Christian Widmann. (2017) The caspase-3/p120 RasGAP stress-sensing module reduces liver cancer incidence but does not affect overall survival in gamma-irradiated and carcinogen-treated mice. Molecular Carcinogenesis 56:6, pages 1680-1684.
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Philip E. Lapinski, Beth A. Lubeck, Di Chen, Abbas Doosti, Scott D. Zawieja, Michael J. Davis & Philip D. King. (2017) RASA1 regulates the function of lymphatic vessel valves in mice. Journal of Clinical Investigation 127:7, pages 2569-2585.
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Xiaoyan Li, Xin Zhuang, Tianchi Xu, Min Mao, Cong Wang, Yabing Chen, Xiaodong Han & Jiang Wu. (2017) Expression analysis of microRNAs and mRNAs in ovarian granulosa cells after microcystin-LR exposure. Toxicon 129, pages 11-19.
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Pelagia Tsoutsou, Alessandro Annibaldi, David Viertl, Jonathan Ollivier, Franz Buchegger, Marie-Catherine Vozenin, Jean Bourhis, Christian Widmann & Oscar Matzinger. (2017) TAT-RasGAP317–326 Enhances Radiosensitivity of Human Carcinoma Cell Lines In Vitro and In Vivo through Promotion of Delayed Mitotic Cell Death. Radiation Research 187:5, pages 562.
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Anne Hennig, Robby Markwart, Katharina Wolff, Katja Schubert, Yan Cui, Ian A. Prior, Manuel A. Esparza-Franco, Graham Ladds & Ignacio Rubio. (2016) Feedback activation of neurofibromin terminates growth factor-induced Ras activation. Cell Communication and Signaling 14:1.
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Katia Cailliau, Arlette Lescuyer, Anne-Françoise Burnol, Álvaro Cuesta-Marbán, Christian Widmann & Edith Browaeys-Poly. (2015) RasGAP Shields Akt from Deactivating Phosphatases in Fibroblast Growth Factor Signaling but Loses This Ability Once Cleaved by Caspase-3. Journal of Biological Chemistry 290:32, pages 19653-19665.
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Hadi Khalil, Noureddine Loukili, Alexandre Regamey, Alvaro Cuesta-Marban, Elettra Santori, Marcel Huber & Christian Widmann. (2015) The caspase-3/p120 RasGAP module generates a NF-κB repressor in response to cellular stress. Journal of Cell Science.
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Güliz Vanli, Nieves Peltzer, Gilles Dubuis & Christian Widmann. (2014) The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity. Cellular Signalling 26:12, pages 2992-2997.
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D Barras, G Lorusso, C Rüegg & C Widmann. (2013) Inhibition of cell migration and invasion mediated by the TAT-RasGAP317–326 peptide requires the DLC1 tumor suppressor. Oncogene 33:44, pages 5163-5172.
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David Barras, Nadja Chevalier, Vincent Zoete, Rosemary Dempsey, Karine Lapouge, Monilola A. Olayioye, Olivier Michielin & Christian Widmann. (2014) A WXW Motif Is Required for the Anticancer Activity of the TAT-RasGAP317–326 Peptide. Journal of Biological Chemistry 289:34, pages 23701-23711.
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David Barras, Girieca Lorusso, Benoît Lhermitte, David Viertl, Curzio Rüegg & Christian Widmann. (2014) Fragment N2, a caspase‐3‐generated RasGAP fragment, inhibits breast cancer metastatic progression. International Journal of Cancer 135:1, pages 242-247.
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Hadi Khalil, Mathieu J.M. Bertrand, Peter Vandenabeele & Christian Widmann. (2014) Caspase-3 and RasGAP: a stress-sensing survival/demise switch. Trends in Cell Biology 24:2, pages 83-89.
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Angela Poehlmann, Kathrin Reissig, Andrea Just, Diana Walluscheck, Roland Hartig, Antje Schinlauer, Wiebke Lessel, Thomas Guenther, Andrew Silver, Pablo Steinberg & Albert Roessner. (2013) Non-apoptotic function of caspases in a cellular model of hydrogen peroxide-associated colitis. Journal of Cellular and Molecular Medicine 17:7, pages 901-913.
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Nieves Peltzer, Güliz Vanli, Jiang-Yan Yang & Christian Widmann. (2013) Role of mTOR, Bad, and Survivin in RasGAP Fragment N-Mediated Cell Protection. PLoS ONE 8:6, pages e68123.
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Hao Zhang, Shenghua Zhang, Hongwei He, Wuli Zhao, Jianhua Chen & Rong-guang Shao. (2012) GAP161 targets and downregulates G3BP to suppress cell growth and potentiate cisplaitin-mediated cytotoxicity to colon carcinoma HCT116 cells. Cancer Science 103:10, pages 1848-1856.
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Hadi Khalil, Nathalie Rosenblatt, Lucas Liaudet & Christian Widmann. (2012) The role of endogenous and exogenous RasGAP-derived fragment N in protecting cardiomyocytes from peroxynitrite-induced apoptosis. Free Radical Biology and Medicine 53:4, pages 926-935.
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Subhasree Basu, Suren Rajakaruna & A. Sue Menko. (2012) Insulin-like Growth Factor Receptor-1 and Nuclear Factor κB Are Crucial Survival Signals That Regulate Caspase-3-mediated Lens Epithelial Cell Differentiation Initiation. Journal of Biological Chemistry 287:11, pages 8384-8397.
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Alessandro Annibaldi, Aline Dousse, Sophie Martin, Jamal Tazi & Christian Widmann. (2011) Revisiting G3BP1 as a RasGAP Binding Protein: Sensitization of Tumor Cells to Chemotherapy by the RasGAP 317–326 Sequence Does Not Involve G3BP1. PLoS ONE 6:12, pages e29024.
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Josiane P. Lafleur, Detlef Snakenborg, Søren S. Nielsen, Magda Møller, Katrine N. Toft, Andreas Menzel, Jes K. Jacobsen, Bente Vestergaard, Lise Arleth & Jörg P. Kutter. (2011) Automated microfluidic sample-preparation platform for high-throughput structural investigation of proteins by small-angle X-ray scattering. Journal of Applied Crystallography 44:5, pages 1090-1099.
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Marija Ger, Zigmantas Zitkus & Mindaugas Valius. (2011) Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity. Cellular Signalling 23:10, pages 1651-1658.
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Hao Zhang, Shenghua Zhang, Hongwei He, Wuli Zhao, Kaihuan Ren, Jianhua Chen & Rong-guang Shao. (2011) RasGAP-derived peptide 38GAP potentiates the cytotoxicity of cisplatin through inhibitions of Akt, ERK and NF-κB in colon carcinoma HCT116 cells. Cancer Letters 308:1, pages 62-70.
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Natasa Bulat, Evrim Jaccard, Nieves Peltzer, Hadi Khalil, Jiang-Yan Yang, Gilles Dubuis & Christian Widmann. (2011) RasGAP-Derived Fragment N Increases the Resistance of Beta Cells towards Apoptosis in NOD Mice and Delays the Progression from Mild to Overt Diabetes. PLoS ONE 6:7, pages e22609.
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Mahesh Vaishnav, Marion MacFarlane & Martin Dickens. (2011) Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis. Experimental Cell Research 317:7, pages 1028-1039.
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Maren Paulsen & Ottmar Janssen. (2011) Pro- and anti-apoptotic CD95 signaling in T cells. Cell Communication and Signaling 9:1, pages 7.
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Masha Dobkin-Bekman, Liat Rahamim Ben-Navi, Boris Shterntal, Ludmila Sviridonov, Fiorenza Przedecki, Michal Naidich-Exler, Chaya Brodie, Rony Seger & Zvi Naor. (2010) Differential Role of PKC Isoforms in GnRH and Phorbol 12-Myristate 13-Acetate Activation of Extracellular Signal-Regulated Kinase and Jun N-Terminal Kinase. Endocrinology 151:10, pages 4894-4907.
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Jiangning Song, Hao Tan, Hongbin Shen, Khalid Mahmood, Sarah E. Boyd, Geoffrey I. Webb, Tatsuya Akutsu & James C. Whisstock. (2010) Cascleave: towards more accurate prediction of caspase substrate cleavage sites. Bioinformatics 26:6, pages 752-760.
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Azi Lipshtat, Gomathi Jayaraman, John Cijiang He & Ravi Iyengar. (2009) Design of versatile biochemical switches that respond to amplitude, duration, and spatial cues. Proceedings of the National Academy of Sciences 107:3, pages 1247-1252.
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Jiang-Yan YangJöel WalickiEvrim JaccardGilles DubuisNatasa BulatJean-Pierre HornungBernard ThorensChristian Widmann. (2009) Expression of the NH2-Terminal Fragment of RasGAP in Pancreatic β-Cells Increases Their Resistance to Stresses and Protects Mice From Diabetes. Diabetes 58:11, pages 2596-2606.
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Masha Dobkin-Bekman, Michal Naidich, Liat Rahamim, Fiorenza Przedecki, Tal Almog, Stefan Lim, Philippa MelamedPing Liu, Thorsten Wohland, Zhong Yao, Rony Seger & Zvi Naor. (2009) A Preformed Signaling Complex Mediates GnRH-Activated ERK Phosphorylation of Paxillin and FAK at Focal Adhesions in LβT2 Gonadotrope Cells. Molecular Endocrinology 23:11, pages 1850-1864.
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Natasa Bulat & Christian Widmann. (2009) Caspase substrates and neurodegenerative diseases. Brain Research Bulletin 80:4-5, pages 251-267.
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S. Lesven & V. Kerlan. (2009) Apoptose et cellule β : de la physiologie au diabète. D’après la conférence de Christian Widmann (Lausanne), Congrès de l’ALFEDIAM, 26 mars 2008. Annales d'Endocrinologie 70:4, pages 261-262.
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Marion CornuJiang-Yan YangEvrim JaccardCarine PoussinChristian WidmannBernard Thorens. (2009) Glucagon-Like Peptide-1 Protects β-Cells Against Apoptosis by Increasing the Activity of an Igf-2/Igf-1 Receptor Autocrine Loop. Diabetes 58:8, pages 1816-1825.
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Alessandro Annibaldi, David Michod, Linda Vanetta, Steeve Cruchet, Pascal Nicod, Gilles Dubuis, Christelle Bonvin & Christian Widmann. (2009) Role of the sub-cellular localization of RasGAP fragment N2 for its ability to sensitize cancer cells to genotoxin-induced apoptosis. Experimental Cell Research 315:12, pages 2081-2091.
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David Michod, Alessandro Annibaldi, Stephan Schaefer, Christine Dapples, Bertrand Rochat & Christian Widmann. (2009) Effect of RasGAP N2 Fragment–Derived Peptide on Tumor Growth in Mice. JNCI: Journal of the National Cancer Institute 101:11, pages 828-832.
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Valérie Plaisance, Véronique Perret, Dimitri Favre, Amar Abderrahmani, Jiang-Yan Yang, Christian Widmann & Romano Regazzi. (2009) Role of the transcriptional factor C/EBPβ in free fatty acid-elicited β-cell failure. Molecular and Cellular Endocrinology 305:1-2, pages 47-55.
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Ching-Nen Nathan Chen, Hau-Ren Chen, Su-Ying Yeh, Gina Vittore & Tuan-Hua David Ho. (2009)
Autophagy Is Enhanced and Floral Development Is Impaired in
AtHVA22d
RNA Interference Arabidopsis
. Plant Physiology 149:4, pages 1679-1689.
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Perayot Pamonsinlapatham, Réda Hadj-Slimane, Yves Lepelletier, Barbara Allain, Mirco Toccafondi, Christiane Garbay & Françoise Raynaud. (2009) P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling. Biochimie 91:3, pages 320-328.
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Natasa Bulat, Gérard Waeber & Christian Widmann. (2009) LDLs stimulate p38 MAPKs and wound healing through SR-BI independently of Ras and PI3 kinase. Journal of Lipid Research 50:1, pages 81-89.
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Perayot Pamonsinlapatham, Brunilde Gril, Sylvie Dufour, Réda Hadj-Slimane, Véronique Gigoux, Stéphanie Pethe, Sébastien L'Hoste, Jacques Camonis, Christiane Garbay, Françoise Raynaud & Michel Vidal. (2008) Capns1, a new binding partner of RasGAP-SH3 domain in K-RasV12 oncogenic cells: Modulation of cell survival and migration. Cellular Signalling 20:11, pages 2119-2126.
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Natasa Bulat & Christian Widmann. (2008)
Generation of a tightly regulated all-
cis
β cell-specific tetracycline-inducible vector
. BioTechniques 45:4, pages 411-420.
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Perayot Pamonsinlapatham, Réda Hadj-Slimane, Françoise Raynaud, Marc Bickle, Claudine Corneloup, Audrey Barthelaix, Yves Lepelletier, Perrine Mercier, Matthieu Schapira, Jérôme Samson, Anne-Laure Mathieu, Nicolas Hugo, Olivier Moncorgé, Ivan Mikaelian, Sylvie Dufour, Christiane Garbay & Pierre Colas. (2008) A RasGAP SH3 Peptide Aptamer Inhibits RasGAP-Aurora Interaction and Induces Caspase-Independent Tumor Cell Death. PLoS ONE 3:8, pages e2902.
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D Tulasne & B Foveau. (2007) The shadow of death on the MET tyrosine kinase receptor. Cell Death & Differentiation 15:3, pages 427-434.
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Philip E. Lapinski, Timothy J. Bauler, Eric J. Brown, Elizabeth D. Hughes, Thomas L. Saunders & Philip D. King. (2007) Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein. genesis 45:12, pages 762-767.
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Jiang-Yan Yang, Nathalie Moulin, Miguel X. van Bemmelen, Gilles Dubuis, Thomas Tawadros, Jacques-Antoine Haefliger, Gérard Waeber & Christian Widmann. (2007) Splice variant-specific stabilization of JNKs by IB1/JIP1. Cellular Signalling 19:10, pages 2201-2207.
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David Michod & Christian Widmann. (2007) DNA-damage sensitizers: Potential new therapeutical tools to improve chemotherapy. Critical Reviews in Oncology/Hematology 63:2, pages 160-171.
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Peter H. Krammer, Rüdiger Arnold & Inna N. Lavrik. (2007) Life and death in peripheral T cells. Nature Reviews Immunology 7:7, pages 532-542.
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Olivier Pittet, David Petermann, David Michod, Thorsten Krueger, Cai Cheng, Hans-Beat Ris & Christian Widmann. (2007) Effect of the TAT-RasGAP317–326 peptide on apoptosis of human malignant mesothelioma cells and fibroblasts exposed to meso-tetra-hydroxyphenyl-chlorin and light. Journal of Photochemistry and Photobiology B: Biology 88:1, pages 29-35.
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Huawen Lin & Ursula W Goodenough. (2007)
Gametogenesis in the
Chlamydomonas reinhardtii minus
Mating Type Is Controlled by Two Genes,
MID
and
MTD1
. Genetics 176:2, pages 913-925.
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Barbara Fischer, Marin Marinov & Alexandre Arcaro. (2007) Targeting receptor tyrosine kinase signalling in small cell lung cancer (SCLC): What have we learned so far?. Cancer Treatment Reviews 33:4, pages 391-406.
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David Michod & Christian Widmann. (2007) TAT-RasGAP317-326 Requires p53 and PUMA to Sensitize Tumor Cells to Genotoxins. Molecular Cancer Research 5:5, pages 497-507.
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B Foveau, C Leroy, F Ancot, J Deheuninck, Z Ji, V Fafeur & D Tulasne. (2006) Amplification of apoptosis through sequential caspase cleavage of the MET tyrosine kinase receptor. Cell Death & Differentiation 14:4, pages 752-764.
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Birthe Ross, Ole Kristensen, Dimitri Favre, Joël Walicki, Jette S. Kastrup, Christian Widmann & Michael Gajhede. (2007) High resolution crystal structures of the p120 RasGAP SH3 domain. Biochemical and Biophysical Research Communications 353:2, pages 463-468.
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Christian Widmann. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference
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Christian Widmann. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference
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Xiaoxian Zhao, Dongmei Wang, Zhenwen Zhao, Yingyi Xiao, Saubhik Sengupta, Yijin Xiao, Renliang Zhang, Kirsten Lauber, Sebastian Wesselborg, Li Feng, Tyler M. Rose, Yue Shen, Junjie Zhang, Glenn Prestwich & Yan Xu. (2006) Caspase-3-dependent Activation of Calcium-independent Phospholipase A2 Enhances Cell Migration in Non-apoptotic Ovarian Cancer Cells. Journal of Biological Chemistry 281:39, pages 29357-29368.
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Jiang-Yan Yang, Joël Walicki, Amar Abderrahmani, Marion Cornu, Gérard Waeber, Bernard Thorens & Christian Widmann. (2005) Expression of an Uncleavable N-terminal RasGAP Fragment in Insulin-secreting Cells Increases Their Resistance toward Apoptotic Stimuli without Affecting Their Glucose-induced Insulin Secretion. Journal of Biological Chemistry 280:38, pages 32835-32842.
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Sophie Launay, Olivier Hermine, Michaëla Fontenay, Guido Kroemer, Eric Solary & Carmen Garrido. (2005) Vital functions for lethal caspases. Oncogene 24:33, pages 5137-5148.
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Jiang-Yan Yang, Joël Walicki, David Michod, Gilles Dubuis & Christian Widmann. (2005) Impaired Akt Activity Down-Modulation, Caspase-3 Activation, and Apoptosis in Cells Expressing a Caspase-resistant Mutant of RasGAP at Position 157. Molecular Biology of the Cell 16:8, pages 3511-3520.
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Jacqueline Lypowy, Ieng-Yi Chen & Maha Abdellatif. (2005) An Alliance between Ras GTPase-activating Protein, Filamin C, and RasGTPase-activating Protein SH3 Domain-binding Protein Regulates MyocyteGrowth. Journal of Biological Chemistry 280:27, pages 25717-25728.
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Christophe Lemaire, Nelly Godefroy, Ioana Costina-Parvu, Vincent Rincheval, Flore Renaud, Pascale Trotot, Sylvina Bouleau, Bernard Mignotte & Jean-Luc Vayssière. (2005) Caspase-9 can antagonize p53-induced apoptosis by generating a p76Rb truncated form of Rb. Oncogene 24:20, pages 3297-3308.
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Lyndon Chie, Denise Chung & Matthew R. Pincus. (2005) Specificity of Inhibition of ras-p21 Signal Transduction
by Peptides from GTPase Activating Protein (GAP) and the Son-of Sevenless (SOS) ras-Specific Guanine Nucleotide Exchange Protein. The Protein Journal 24:4, pages 253-258.
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Irene Knuesel, Abigail Elliott, Hong-Jung Chen, Isabelle M. Mansuy & Mary B. Kennedy. (2005) A role for synGAP in regulating neuronal apoptosis. European Journal of Neuroscience 21:3, pages 611-621.
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Achim Temme, Petra Diestelkoetter-Bachert, Marc Schmitz, Agnieszka Morgenroth, Bernd Weigle, Michael A. Rieger, Andrea Kiessling & E. Peter Rieber. (2005) Increased p21ras activity in human fibroblasts transduced with survivin enhances cell proliferation. Biochemical and Biophysical Research Communications 327:3, pages 765-773.
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David Michod, Jiang-Yan Yang, Jianhua Chen, Christophe Bonny & Christian Widmann. (2004) A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells. Oncogene 23:55, pages 8971-8978.
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Jiang-Yan Yang, David Michod, Joël Walicki & Christian Widmann. (2004) Surviving the kiss of death. Biochemical Pharmacology 68:6, pages 1027-1031.
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Sowmini Oomman, Velvetlee Finckbone, Janet Dertien, Jennifer Attridge, William Henne, Margarita Medina, Bobbak Mansouri, Hema Singh, Howard Strahlendorf & Jean Strahlendorf. (2004) Active caspase-3 expression during postnatal development of rat cerebellum is not systematically or consistently associated with apoptosis. The Journal of Comparative Neurology 476:2, pages 154-173.
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Andre Bernards & Jeffrey Settleman. (2004) GAP control: regulating the regulators of small GTPases. Trends in Cell Biology 14:7, pages 377-385.
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Yingzi Yue, Jaqueline Lypowy, Nadia Hedhli & Maha Abdellatif. (2004) Ras GTPase-activating Protein Binds to Akt and Is Required for Its Activation. Journal of Biological Chemistry 279:13, pages 12883-12889.
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James S. Liou, James S. Chen & Douglas V. Faller. (2004) Characterization of p21Ras-mediated apoptosis induced by protein kinase C inhibition and application to human tumor cell lines. Journal of Cellular Physiology 198:2, pages 277-294.
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Adrienne D Cox & Channing J Der. (2003) The dark side of Ras: regulation of apoptosis. Oncogene 22:56, pages 8999-9006.
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Iveta Dobreva, Gérard Waeber, Vincent Mooser, Richard W. James & Christian Widmann. (2003) LDLs induce fibroblast spreading independently of the LDL receptor via activation of the p38 MAPK pathway. Journal of Lipid Research 44:12, pages 2382-2390.
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Christian Schwerk & Klaus Schulze-Osthoff. (2003) Non-apoptotic functions of caspases in cellular proliferation and differentiation. Biochemical Pharmacology 66:8, pages 1453-1458.
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U Fischer, R U Jänicke & K Schulze-Osthoff. (2003) Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death & Differentiation 10:1, pages 76-100.
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Olivier SordetCédric RébéStéphanie PlenchetteYaël ZermatiOlivier HermineWilliam VainchenkerCarmen GarridoEric SolaryLaurence Dubrez-Daloz. (2002) Specific involvement of caspases in the differentiation of monocytes into macrophages. Blood 100:13, pages 4446-4453.
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Sandra Ussat, Ulf-Eike Werner & Sabine Adam-Klages. (2002) Species-specific differences in the usage of several caspase substrates. Biochemical and Biophysical Research Communications 297:5, pages 1186-1190.
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Anne K DeChant, Keith Dee & Crystal M Weyman. (2002) Raf-induced effects on the differentiation and apoptosis of skeletal myoblasts are determined by the level of Raf signaling: abrogation of apoptosis by Raf is downstream of caspase 3 activation. Oncogene 21:34, pages 5268-5279.
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James M. Chen, Fred K. Friedman, Paul W. Brandt-Rauf, Matthew R. Pincus & Lyndon Chie. (2002) Comparison of the Average Structures, from Molecular Dynamics, of Complexes of GTPase Activating Protein (GAP) with Oncogenic and Wild-Type ras-p21: Identification of Potential Effector Domains. Journal of Protein Chemistry 21:5, pages 349-359.
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Véronique Gigoux, Sébastien L'Hoste, Françoise Raynaud, Jacques Camonis & Christiane Garbay. (2002) Identification of Aurora Kinases as RasGAP Src Homology 3 Domain-binding Proteins. Journal of Biological Chemistry 277:26, pages 23742-23746.
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Jiang-Yan Yang & Christian Widmann. (2002) The RasGAP N-terminal Fragment Generated by Caspase Cleavage Protects Cells in a Ras/PI3K/Akt-dependent Manner That Does Not Rely on NFκB Activation. Journal of Biological Chemistry 277:17, pages 14641-14646.
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Thomas K. Schlesinger, Christelle Bonvin, Matthew B. Jarpe, Gary R. Fanger, Jean-René Cardinaux, Gary L. Johnson & Christian Widmann. (2002) Apoptosis Stimulated by the 91-kDa Caspase Cleavage MEKK1 Fragment Requires Translocation to Soluble Cellular Compartments. Journal of Biological Chemistry 277:12, pages 10283-10291.
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