Molecular and Cellular Biology, Volume 21, Issue 16 (2001)

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Molecular and Cellular Biology, Volume 21, Issue 16 (2001)

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Cell Growth and Development

Article
The Insert Region of RhoA Is Essential for Rho Kinase Activation and Cellular Transformation
Hui Zong, Kozo Kaibuchi & Lawrence A. Quilliam
Pages: 5287-5298
Published online: 28 Mar 2023
AbstractforThe Insert Region of RhoA Is Essential for Rho Kinase Activation and Cellular Transformation | Full Text | References | PDF (601 KB)
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Article
NF-κB Signals Induce the Expression of c-FLIP
Olivier Micheau, Susanne Lens, Olivier Gaide, Kostis Alevizopoulos & Jürg Tschopp
Pages: 5299-5305
Published online: 28 Mar 2023
AbstractforNF-κB Signals Induce the Expression of c-FLIP | Full Text | References | PDF (426.3 KB)
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Article
Mice with Very Low Expression of the Vesicular Monoamine Transporter 2 Gene Survive into Adulthood: Potential Mouse Model for Parkinsonism
Katrin A. Mooslehner, Pok Man Chan, Weiming Xu, Lizhi Liu, Claire Smadja, Trevor Humby, Nicholas D. Allen, Lawrence S. Wilkinson & Piers C. Emson
Pages: 5321-5331
Published online: 28 Mar 2023
AbstractforMice with Very Low Expression of the Vesicular Monoamine Transporter 2 Gene Survive into Adulthood: Potential Mouse Model for Parkinsonism | Full Text | References | PDF (663.3 KB)
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Article
Hic-5-Reduced Cell Spreading on Fibronectin: Competitive Effects between Paxillin and Hic-5 through Interaction with Focal Adhesion Kinase
Naoyuki Nishiya, Kouichi Tachibana, Motoko Shibanuma, Jun-Ichi Mashimo & Kiyoshi Nose
Pages: 5332-5345
Published online: 28 Mar 2023
AbstractforHic-5-Reduced Cell Spreading on Fibronectin: Competitive Effects between Paxillin and Hic-5 through Interaction with Focal Adhesion Kinase | Full Text | References | PDF (551.6 KB)
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Article
Antiapoptotic Signaling Generated by Caspase-Induced Cleavage of RasGAP
Jiang-Yan Yang & Christian Widmann
Pages: 5346-5358
Published online: 28 Mar 2023
AbstractforAntiapoptotic Signaling Generated by Caspase-Induced Cleavage of RasGAP | Full Text | References | PDF (681.6 KB)
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Article
Inhibition of the Motility and Growth of B16F10 Mouse Melanoma Cells by Dominant Negative Mutants of Dok-1
Tetsuya Hosooka, Tetsuya Noguchi, Hiroshi Nagai, Tatsuya Horikawa, Takashi Matozaki, Masamitsu Ichihashi & Masato Kasuga
Pages: 5437-5446
Published online: 28 Mar 2023
AbstractforInhibition of the Motility and Growth of B16F10 Mouse Melanoma Cells by Dominant Negative Mutants of Dok-1 | Full Text | References | PDF (513.6 KB)
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Article
Regulation of Id Gene Expression by Type I Insulin-Like Growth Factor: Roles of STAT3 and the Tyrosine 950 Residue of the Receptor
Marco Prisco, Francesca Peruzzi, Barbara Belletti & Renato Baserga
Pages: 5447-5458
Published online: 28 Mar 2023
AbstractforRegulation of Id Gene Expression by Type I Insulin-Like Growth Factor: Roles of STAT3 and the Tyrosine 950 Residue of the Receptor | Full Text | References | PDF (423.4 KB)
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Article
Loss of JunB Activity Enhances Stromelysin 1 Expression in a Model of the Epithelial-to-Mesenchymal Transition of Mouse Skin Tumors
Diana L. Hulboy, Lynn M. Matrisian & Howard C. Crawford
Pages: 5478-5487
Published online: 28 Mar 2023
AbstractforLoss of JunB Activity Enhances Stromelysin 1 Expression in a Model of the Epithelial-to-Mesenchymal Transition of Mouse Skin Tumors | Full Text | References | PDF (316.9 KB)
  • 13 Views
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Article
Oncogenic Ras Blocks Anoikis by Activation of a Novel Effector Pathway Independent of Phosphatidylinositol 3-Kinase
Aidan McFall, Aylin ülkuü, Que T. Lambert, Andrea Kusa, Kelley Rogers-Graham & Channing J. Der
Pages: 5488-5499
Published online: 28 Mar 2023
AbstractforOncogenic Ras Blocks Anoikis by Activation of a Novel Effector Pathway Independent of Phosphatidylinositol 3-Kinase | Full Text | References | PDF (376.7 KB)
  • 16 Views
  • 92 CrossRef citations
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Article
Negative Regulation of Protein Translation by Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2
Ursula Knauf, Claude Tschopp & Hermann Gram
Pages: 5500-5511
Published online: 28 Mar 2023
AbstractforNegative Regulation of Protein Translation by Mitogen-Activated Protein Kinase-Interacting Kinases 1 and 2 | Full Text | References | PDF (633 KB)
  • 59 Views
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Article
Protein Kinase C-δ Regulates Thrombin-Induced ICAM-1 Gene Expression in Endothelial Cells via Activation of p38 Mitogen-Activated Protein Kinase
Arshad Rahman, Khandaker N. Anwar, Shahab Uddin, Ning Xu, Richard D. Ye, Leonidas C. Platanias & Asrar B. Malik
Pages: 5554-5565
Published online: 28 Mar 2023
AbstractforProtein Kinase C-δ Regulates Thrombin-Induced ICAM-1 Gene Expression in Endothelial Cells via Activation of p38 Mitogen-Activated Protein Kinase | Full Text | References | PDF (421.2 KB)
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Article
Dichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation
Sebastien A. Burel, Nari Harakawa, Liming Zhou, Thomas Pabst, Daniel G. Tenen & Dong-Er Zhang
Pages: 5577-5590
Published online: 28 Mar 2023
AbstractforDichotomy of AML1-ETO Functions: Growth Arrest versus Block of Differentiation | Full Text | References | PDF (850.5 KB)
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Article
Increased Susceptibility to Streptozotocin-Induced β-Cell Apoptosis and Delayed Autoimmune Diabetes in Alkylpurine- DNA-N-Glycosylase-Deficient Mice
John W. Cardinal, Geoffrey P. Margison, Kurt J. Mynett, Allen P. Yates, Donald P. Cameron & Rhoderick H. Elder
Pages: 5605-5613
Published online: 28 Mar 2023
AbstractforIncreased Susceptibility to Streptozotocin-Induced β-Cell Apoptosis and Delayed Autoimmune Diabetes in Alkylpurine- DNA-N-Glycosylase-Deficient Mice | Full Text | References | PDF (1.5 MB)
  • 14 Views
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Article
Reconstitution of Cyclin D1-Associated Kinase Activity Drives Terminally Differentiated Cells into the Cell Cycle
Lucia Latella, Alessandra Sacco, Deborah Pajalunga, Marianne Tiainen, Daniela Macera, Marco D'Angelo, Angelina Felici, Ada Sacchi & Marco Crescenzi
Pages: 5631-5643
Published online: 28 Mar 2023
AbstractforReconstitution of Cyclin D1-Associated Kinase Activity Drives Terminally Differentiated Cells into the Cell Cycle | Full Text | References | PDF (2.5 MB)
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Article
Akt-Dependent Phosphorylation of p21Cip1 Regulates PCNA Binding and Proliferation of Endothelial Cells
Lothar Rössig, Amir S. Jadidi, Carmen Urbich, Cornel Badorff, Andreas M. Zeiher & Stefanie Dimmeler
Pages: 5644-5657
Published online: 28 Mar 2023
AbstractforAkt-Dependent Phosphorylation of p21Cip1 Regulates PCNA Binding and Proliferation of Endothelial Cells | Full Text | References | PDF (1.2 MB)
  • 86 Views
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Article
The Elongation Domain of ELL Is Dispensable but Its ELL-Associated Factor 1 Interaction Domain Is Essential for MLL-ELL-Induced Leukemogenesis
Roger T. Luo, Catherine Lavau, Changchun Du, Federico Simone, Paul E. Polak, Shin Kawamata & Michael J. Thirman
Pages: 5678-5687
Published online: 28 Mar 2023
AbstractforThe Elongation Domain of ELL Is Dispensable but Its ELL-Associated Factor 1 Interaction Domain Is Essential for MLL-ELL-Induced Leukemogenesis | Full Text | References | PDF (845.8 KB)
  • 32 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Functional Analysis of Mouse Kinesin Motor Kif3C
Zhaohuai Yang, Elizabeth A. Roberts & Lawrence S. B. Goldstein
Pages: 5306-5311
Published online: 28 Mar 2023
AbstractforFunctional Analysis of Mouse Kinesin Motor Kif3C | Full Text | References | PDF (437.8 KB)
  • 8 Views
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Article
Disruption of γ-Glutamyl Leukotrienase Results in Disruption of Leukotriene D4 Synthesis In Vivo and Attenuation of the Acute Inflammatory Response
Zheng-Zheng Shi, Bing Han, Geetha M. Habib, Martin M. Matzuk & Michael W. Lieberman
Pages: 5389-5395
Published online: 28 Mar 2023
AbstractforDisruption of γ-Glutamyl Leukotrienase Results in Disruption of Leukotriene D4 Synthesis In Vivo and Attenuation of the Acute Inflammatory Response | Full Text | References | PDF (151.1 KB)
  • 9 Views
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Article
Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene
Johan W. Jonker, Els Wagenaar, Carla A. A. M. Mol, Marije Buitelaar, Hermann Koepsell, Johan W. Smit & Alfred H. Schinkel
Pages: 5471-5477
Published online: 28 Mar 2023
AbstractforReduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene | Full Text | References | PDF (122.7 KB)
  • 26 Views
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Article
Preserved Pancreatic β-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor
Tadahiro Kitamura, Yoshiaki Kido, Serge Nef, Jussi Merenmies, Luis F. Parada & Domenico Accili
Pages: 5624-5630
Published online: 28 Mar 2023
AbstractforPreserved Pancreatic β-Cell Development and Function in Mice Lacking the Insulin Receptor-Related Receptor | Full Text | References | PDF (525.2 KB)
  • 42 Views
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Article
Gene Targeting Reveals a Crucial Role forMTG8 in the Gut
Franco Calabi, Richard Pannell & Gordana Pavloska
Pages: 5658-5666
Published online: 28 Mar 2023
AbstractforGene Targeting Reveals a Crucial Role forMTG8 in the Gut | Full Text | References | PDF (1.9 MB)
  • 12 Views
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Article
A Murine Homologue of the Drosophila brainiac Gene Shows Homology to Glycosyltransferases and Is Required for Preimplantation Development of the Mouse
Benedikt Vollrath, Kevin J. Fitzgerald & Philip Leder
Pages: 5688-5697
Published online: 28 Mar 2023
AbstractforA Murine Homologue of the Drosophila brainiac Gene Shows Homology to Glycosyltransferases and Is Required for Preimplantation Development of the Mouse | Full Text | References | PDF (1.5 MB)
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Transcriptional Regulation

Article
Interaction between Acetylated MyoD and the Bromodomain of CBP and/or p300
Anna Polesskaya, Irina Naguibneva, Arnaud Duquet, Eyal Bengal, Philippe Robin & Annick Harel-Bellan
Pages: 5312-5320
Published online: 28 Mar 2023
AbstractforInteraction between Acetylated MyoD and the Bromodomain of CBP and/or p300 | Full Text | References | PDF (309.6 KB)
  • 19 Views
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Article
Histone H1 Phosphorylation by Cdk2 Selectively Modulates Mouse Mammary Tumor Virus Transcription through Chromatin Remodeling
Rabindra N. Bhattacharjee, Geoffrey C. Banks, Kevin W. Trotter, Huay-Leng Lee & Trevor K. Archer
Pages: 5417-5425
Published online: 28 Mar 2023
AbstractforHistone H1 Phosphorylation by Cdk2 Selectively Modulates Mouse Mammary Tumor Virus Transcription through Chromatin Remodeling | Full Text | References | PDF (264.2 KB)
  • 14 Views
  • 86 CrossRef citations
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Article
DNA Methylation Is Linked to Deacetylation of Histone H3, but Not H4, on the Imprinted Genes Snrpnand U2af1-rs1
Richard I. Gregory, Tamzin E. Randall, Colin A. Johnson, Sanjeev Khosla, Izuho Hatada, Laura P. O'Neill, Bryan M. Turner & Robert Feil
Pages: 5426-5436
Published online: 28 Mar 2023
AbstractforDNA Methylation Is Linked to Deacetylation of Histone H3, but Not H4, on the Imprinted Genes Snrpnand U2af1-rs1 | Full Text | References | PDF (302.3 KB)
  • 16 Views
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Article
The Oncoprotein Tax Binds the SRC-1-Interacting Domain of CBP/p300 To Mediate Transcriptional Activation
Kirsten E. S. Scoggin, Aida Ulloa & Jennifer K. Nyborg
Pages: 5520-5530
Published online: 28 Mar 2023
AbstractforThe Oncoprotein Tax Binds the SRC-1-Interacting Domain of CBP/p300 To Mediate Transcriptional Activation | Full Text | References | PDF (362.2 KB)
  • 9 Views
  • 54 CrossRef citations
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Article
Reconstitution of Enhancer Function in Paternal Pronuclei of One-Cell Mouse Embryos
Luca Rastelli, Karen Robinson, Yanbo Xu & Sadhan Majumder
Pages: 5531-5540
Published online: 28 Mar 2023
AbstractforReconstitution of Enhancer Function in Paternal Pronuclei of One-Cell Mouse Embryos | Full Text | References | PDF (269.7 KB)
  • 3 Views
  • 12 CrossRef citations
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Article
Analysis of Ankyrin Repeats Reveals How a Single Point Mutation in RFXANK Results in Bare Lymphocyte Syndrome
Nada Nekrep, Matthias Geyer, Nabila Jabrane-Ferrat & B. Matija Peterlin
Pages: 5566-5576
Published online: 28 Mar 2023
AbstractforAnalysis of Ankyrin Repeats Reveals How a Single Point Mutation in RFXANK Results in Bare Lymphocyte Syndrome | Full Text | References | PDF (1 MB)
  • 12 Views
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Dna Dynamics and Chromosome Structure

Article
SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome
Craig B. Bennett, Joyce R. Snipe, James W. Westmoreland & Michael A. Resnick
Pages: 5359-5373
Published online: 28 Mar 2023
AbstractforSIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome | Full Text | References | PDF (616.2 KB)
  • 6 Views
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Article
The Sgs1 Helicase of Saccharomyces cerevisiae Inhibits Retrotransposition of Ty1 Multimeric Arrays
Mary Bryk, Mukti Banerjee, Darryl Conte Jr. & M. Joan Curcio
Pages: 5374-5388
Published online: 28 Mar 2023
AbstractforThe Sgs1 Helicase of Saccharomyces cerevisiae Inhibits Retrotransposition of Ty1 Multimeric Arrays | Full Text | References | PDF (511.5 KB)
  • 5 Views
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Article
High-Copy-Number Expression of Sub2p, a Member of the RNA Helicase Superfamily, Suppresses hpr1-Mediated Genomic Instability
Hua-Ying Fan, Robert J. Merker & Hannah L. Klein
Pages: 5459-5470
Published online: 28 Mar 2023
AbstractforHigh-Copy-Number Expression of Sub2p, a Member of the RNA Helicase Superfamily, Suppresses hpr1-Mediated Genomic Instability | Full Text | References | PDF (527.5 KB)
  • 10 Views
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Article
SATB1 Cleavage by Caspase 6 Disrupts PDZ Domain-Mediated Dimerization, Causing Detachment from Chromatin Early in T-Cell Apoptosis
Sanjeev Galande, Liliane A. Dickinson, I. Saira Mian, Marianna Sikorska & Terumi Kohwi-Shigematsu
Pages: 5591-5604
Published online: 28 Mar 2023
AbstractforSATB1 Cleavage by Caspase 6 Disrupts PDZ Domain-Mediated Dimerization, Causing Detachment from Chromatin Early in T-Cell Apoptosis | Full Text | References | PDF (695.6 KB)
  • 21 Views
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Article
A Meiotic Chromosomal Core Consisting of Cohesin Complex Proteins Recruits DNA Recombination Proteins and Promotes Synapsis in the Absence of an Axial Element in Mammalian Meiotic Cells
Jeanette Pelttari, Mary-Rose Hoja, Li Yuan, Jian-Guo Liu, Eva Brundell, Peter Moens, Sabine Santucci-Darmanin, Rolf Jessberger, Jose Luis Barbero, Christa Heyting & Christer Höög
Pages: 5667-5677
Published online: 28 Mar 2023
AbstractforA Meiotic Chromosomal Core Consisting of Cohesin Complex Proteins Recruits DNA Recombination Proteins and Promotes Synapsis in the Absence of an Axial Element in Mammalian Meiotic Cells | Full Text | References | PDF (3.2 MB)
  • 38 Views
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Nucleocytoplasmic Communication

Article
Nucleocytoplasmic Distribution of the Ovalbumin Serpin PI-9 Requires a Nonconventional Nuclear Import Pathway and the Export Factor Crm1
Catherina H. Bird, Elizabeth J. Blink, Claire E. Hirst, Marguerite S. Buzza, Pauline M. Steele, Jiuru Sun, David A. Jans & Phillip I. Bird
Pages: 5396-5407
Published online: 28 Mar 2023
AbstractforNucleocytoplasmic Distribution of the Ovalbumin Serpin PI-9 Requires a Nonconventional Nuclear Import Pathway and the Export Factor Crm1 | Full Text | References | PDF (492.1 KB)
  • 28 Views
  • 80 CrossRef citations
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Gene Expression

Article
Polynucleotide Phosphorylase Functions as Both an Exonuclease and a Poly(A) Polymerase in Spinach Chloroplasts
Shlomit Yehudai-Resheff, Merav Hirsh & Gadi Schuster
Pages: 5408-5416
Published online: 28 Mar 2023
AbstractforPolynucleotide Phosphorylase Functions as Both an Exonuclease and a Poly(A) Polymerase in Spinach Chloroplasts | Full Text | References | PDF (297.3 KB)
  • 28 Views
  • 129 CrossRef citations
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Article
Nonsense-Mediated Decay of HumanHEXA mRNA
Kavitha S. Rajavel & Elizabeth F. Neufeld
Pages: 5512-5519
Published online: 28 Mar 2023
AbstractforNonsense-Mediated Decay of HumanHEXA mRNA | Full Text | References | PDF (268 KB)
  • 29 Views
  • 65 CrossRef citations
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Article
Yeast RNA Polymerase I Enhancer Is Dispensable for Transcription of the Chromosomal rRNA Gene and Cell Growth, and Its Apparent Transcription Enhancement from Ectopic Promoters Requires Fob1 Protein
Hobert Wai, Katsuki Johzuka, Loan Vu, Kristilyn Eliason, Takehiko Kobayashi, Takashi Horiuchi & Masayasu Nomura
Pages: 5541-5553
Published online: 28 Mar 2023
AbstractforYeast RNA Polymerase I Enhancer Is Dispensable for Transcription of the Chromosomal rRNA Gene and Cell Growth, and Its Apparent Transcription Enhancement from Ectopic Promoters Requires Fob1 Protein | Full Text | References | PDF (471.4 KB)
  • 12 Views
  • 30 CrossRef citations
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Article
Identification and Functional Characterization of Neo-Poly(A) Polymerase, an RNA Processing Enzyme Overexpressed in Human Tumors
Suzanne L. Topalian, Syuzo Kaneko, Monica I. Gonzales, Gareth L. Bond, Yvona Ward & James L. Manley
Pages: 5614-5623
Published online: 28 Mar 2023
AbstractforIdentification and Functional Characterization of Neo-Poly(A) Polymerase, an RNA Processing Enzyme Overexpressed in Human Tumors | Full Text | References | PDF (587.7 KB)
  • 23 Views
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