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Molecular and Cellular Biology Volume 21, 2001 - Issue 2
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DNA Dynamics and Chromosome Structure

The Mechanism of Mammalian Gene Replacement Is Consistent with the Formation of Long Regions of Heteroduplex DNA Associated with Two Crossing-Over Events

Julang Li1 Department of Molecular Biology and GeneticsCorrespondence[email protected]
,
Leah R. Read2 Department of Pathobiology, University of Guelph, Guelph, Ontario, CanadaN1G 2W1
&
Mark D. Baker1 Department of Molecular Biology and Genetics;2 Department of Pathobiology, University of Guelph, Guelph, Ontario, CanadaN1G 2W1
Pages 501-510 | Received 14 Jul 2000, Accepted 18 Oct 2000, Published online: 28 Mar 2023

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Genrikh S. Ritter, Valeriy P. Nikolin, Nelly A. Popova, Anastasia S. Proskurina, Polina E. Kisaretova, Oleg S. Taranov, Tatiana D. Dubatolova, Evgenia V. Dolgova, Ekaterina A. Potter, Svetlana S. Kirikovich, Yaroslav R. Efremov, Sergey I. Bayborodin, Margarita V. Romanenko, Maria I. Meschaninova, Aliya G. Venyaminova, Nikolay A. Kolchanov, Mikhail A. Shurdov & Sergey S. Bogachev. (2020) Characterization of biological peculiarities of the radioprotective activity of double-stranded RNA isolated from Saccharomyces сerevisiae. International Journal of Radiation Biology 96:9, pages 1173-1191.
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Efrem A. H. Neuwirth, Masamitsu Honma & Andrew J. Grosovsky. (2007) Interchromosomal Crossover in Human Cells Is Associated with Long Gene Conversion Tracts. Molecular and Cellular Biology 27:15, pages 5261-5274.
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Beth Elliott & Maria Jasin. (2001) Repair of Double-Strand Breaks by Homologous Recombination in Mismatch Repair-Defective Mammalian Cells. Molecular and Cellular Biology 21:8, pages 2671-2682.
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Jasmine Edelstein, Marshall Fritz & Samuel K. Lai. (2022) Challenges and opportunities in gene editing of B cells. Biochemical Pharmacology 206, pages 115285.
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G. S. Ritter, V. P. Nikolin, N. A. Popova, A. S. Proskurina, P. E. Kisaretova, O. S. Taranov, T. D. Dubatolova, E. V. Dolgova, E. A. Potter, S. S. Kirikovich, Y. R. Efremov, S. I. Bayborodin, M. V. Romanenko, M. I. Meschaninova, A. G. Venyaminova, N. A. Kolchanov & S. S. Bogachev. (2020) Characteristic of the active substance of the Saccharomyces cerevisiae preparation having radioprotective properties. Vavilov Journal of Genetics and Breeding 24:6, pages 643-652.
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Huei-Mei Chen, Rachel Resendes, Azita Ghodssi, Danielle Sookiasian, Michael Tian, Serena Dollive, Laura Adamson-Small, Nancy Avila, Cagdas Tazearslan, John F. Thompson, Jeff L. Ellsworth, Omar Francone, Albert Seymour & Jason B. Wright. (2020) Molecular characterization of precise in vivo targeted gene integration in human cells using AAVHSC15. PLOS ONE 15:5, pages e0233373.
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Alissa C. Magwood, Maureen M. Mundia, Samanta M. Pladwig, Dick D. Mosser & Mark D. Baker. (2020) The dichotomous effects of caffeine on homologous recombination in mammalian cells. DNA Repair 88, pages 102805.
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Donna J. Palmer, Nathan C. Grove, Dustin L. Turner & Philip Ng. (2017) Gene Editing with Helper-Dependent Adenovirus Can Efficiently Introduce Multiple Changes Simultaneously over a Large Genomic Region. Molecular Therapy - Nucleic Acids 8, pages 101-110.
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Yinan Kan, Brian Ruis, Taylor Takasugi & Eric A. Hendrickson. (2017) Mechanisms of precise genome editing using oligonucleotide donors. Genome Research 27:7, pages 1099-1111.
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Mark Pogson, Cristina Parola, William J. Kelton, Paul Heuberger & Sai T. Reddy. (2016) Immunogenomic engineering of a plug-and-(dis)play hybridoma platform. Nature Communications 7:1.
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Anastasia S Proskurina, Tatiana S Gvozdeva, Ekaterina A Alyamkina, Evgenia V Dolgova, Konstantin E Orishchenko, Valeriy P Nikolin, Nelly A Popova, Sergey V Sidorov, Elena R Chernykh, Alexandr A Ostanin, Olga Y Leplina, Victoria V Dvornichenko, Dmitriy M Ponomarenko, Galina S Soldatova, Nikolay A Varaksin, Tatiana G Ryabicheva, Stanislav N Zagrebelniy, Vladimir A Rogachev, Sergey S Bogachev & Mikhail A Shurdov. (2015) Results of multicenter double-blind placebo-controlled phase II clinical trial of Panagen preparation to evaluate its leukostimulatory activity and formation of the adaptive immune response in patients with stage II-IV breast cancer. BMC Cancer 15:1.
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Yinan Kan, Brian Ruis, Sherry Lin & Eric A. Hendrickson. (2014) The Mechanism of Gene Targeting in Human Somatic Cells. PLoS Genetics 10:4, pages e1004251.
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Jennifer J. Rahn, Brian Rowley, Megan P. Lowery, Luis Della Coletta, Tiffany Limanni, Rodney S. Nairn & Gerald M. Adair. (2011) Effects of varying gene targeting parameters on processing of recombination intermediates by ERCC1–XPF. DNA Repair 10:2, pages 188-198.
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Aswin Mangerich, Harry Scherthan, Jörg Diefenbach, Ulrich Kloz, Franciscus van der Hoeven, Sascha Beneke & Alexander Bürkle. (2008) A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1. Transgenic Research 18:2, pages 261-279.
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Y. Johzuka-Hisatomi, R. Terada & S. Iida. (2008) Efficient transfer of base changes from a vector to the rice genome by homologous recombination: involvement of heteroduplex formation and mismatch correction. Nucleic Acids Research 36:14, pages 4727-4735.
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Rebecca L. Barnes & Richard McCulloch. (2007) Trypanosoma brucei homologous recombination is dependent on substrate length and homology, though displays a differential dependence on mismatch repair as substrate length decreases. Nucleic Acids Research 35:10, pages 3478-3493.
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Lance D Langston & Lorraine S Symington. (2005) Opposing roles for DNA structure-specific proteins Rad1, Msh2, Msh3, and Sgs1 in yeast gene targeting. The EMBO Journal 24:12, pages 2214-2223.
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Lance D. Langston & Lorraine S. Symington. (2004) Gene targeting in yeast is initiated by two independent strand invasions. Proceedings of the National Academy of Sciences 101:43, pages 15392-15397.
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Richard D McCulloch, Leah R Read & Mark D Baker. (2003) Strand Invasion and DNA Synthesis From the Two 3′ Ends of a Double-Strand Break in Mammalian Cells. Genetics 163:4, pages 1439-1447.
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Diana Ronai, Emily Y. Cheng, Catherine Collins & Marc J. Shulman. (2003) Use of a simple, general targeting vector for replacing the DNA of the heavy chain constant region in mouse hybridoma cells. Journal of Immunological Methods 275:1-2, pages 191-202.
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Tipayaratn Musikacharoen, Yasunobu Yoshikai & Tetsuya Matsuguchi. (2003) Histone Acetylation and Activation of cAMP-response Element-binding Protein Regulate Transcriptional Activation of MKP-M in Lipopolysaccharide-stimulated Macrophages. Journal of Biological Chemistry 278:11, pages 9167-9175.
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Élodie Biet, Lionel Larue & Marie Dutreix. (2003) Recombinaison homologue et ciblage de gène. Comptes Rendus Biologies 326:1, pages 51-64.
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Alberto Martin & Matthew D. Scharff. (2002) AID and mismatch repair in antibody diversification. Nature Reviews Immunology 2:8, pages 605-614.
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