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Gene Expression

The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR

Jonathan L. E. DeanKennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, LondonW6 8LH, United KingdomCorrespondence[email protected]
,
Robin WaitKennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, LondonW6 8LH, United Kingdom
,
Kamal R. MahtaniKennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, LondonW6 8LH, United Kingdom
,
Gareth SullyKennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, LondonW6 8LH, United Kingdom
,
Andrew R. ClarkKennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, LondonW6 8LH, United Kingdom
&
Jeremy SaklatvalaKennedy Institute of Rheumatology Division, Imperial College School of Medicine, Hammersmith, LondonW6 8LH, United Kingdom
Pages 721-730 | Received 04 Aug 2000, Accepted 08 Nov 2000, Published online: 27 Mar 2023

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Eva Matoulkova, Eva Michalova, Borivoj Vojtesek & Roman Hrstka. (2012) The role of the 3' untranslated region in post-transcriptional regulation of protein expression in mammalian cells.. RNA Biology 9:5, pages 563-576.
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Reinhard Winzen, Gayatri Gowrishankar, Frank Bollig, Natalie Redich, Klaus Resch & Helmut Holtmann. (2004) Distinct Domains of AU-Rich Elements Exert Different Functions in mRNA Destabilization and Stabilization by p38 Mitogen-Activated Protein Kinase or HuR. Molecular and Cellular Biology 24:11, pages 4835-4847.
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Hoanh Tran, Fabienne Maurer & Yoshikuni Nagamine. (2003) Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2. Molecular and Cellular Biology 23:20, pages 7177-7188.
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B. JoNell Hamilton, Anna Genin, Randy Q. Cron & William F. C. Rigby. (2003) Delineation of a Novel Pathway That Regulates CD154 (CD40 Ligand) Expression. Molecular and Cellular Biology 23:2, pages 510-525.
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Chyi-Ying A. Chen, Nianhua Xu & Ann-Bin Shyu. (2002) Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization. Molecular and Cellular Biology 22:20, pages 7268-7278.
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Crossref
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Crossref
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Crossref
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Crossref
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Crossref
Virginia E. Glazier, Jan Naseer Kaur, Nancy T. Brown, Ashley A. Rivera & John C. Panepinto. (2015) Puf4 Regulates both Splicing and Decay of HXL1 mRNA Encoding the Unfolded Protein Response Transcription Factor in Cryptococcus neoformans . Eukaryotic Cell 14:4, pages 385-395.
Crossref
Franziska Bollmann, Julia Art, Jenny Henke, Katharina Schrick, Verena Besche, Matthias Bros, Huige Li, Daniel Siuda, Norbert Handler, Florian Bauer, Thomas Erker, Felix Behnke, Bettina Mönch, Lorena Härdle, Markus Hoffmann, Ching-Yi Chen, Ulrich Förstermann, Verena M. Dirsch, Oliver Werz, Hartmut Kleinert & Andrea Pautz. (2014) Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity. Nucleic Acids Research 42:20, pages 12555-12569.
Crossref
WenGong Wang. (2014) HuR and post-transcriptional regulation in vascular aging. Science China Life Sciences 57:8, pages 863-866.
Crossref
Ronaldo P. PanganibanBecky M. VonakisFaoud T. IshmaelCristiana Stellato. (2014) Coordinated Post-Transcriptional Regulation of the Chemokine System: Messages from CCL2. Journal of Interferon & Cytokine Research 34:4, pages 255-266.
Crossref
Irina Vlasova-St. LouisPaul R. Bohjanen. (2014) Post-Transcriptional Regulation of Cytokine Signaling by AU-Rich and GU-Rich Elements. Journal of Interferon & Cytokine Research 34:4, pages 233-241.
Crossref
José A. González-Feliciano, Marimar Hernández-Pérez, Luis A. Estrella, Daisy D. Colón-López, Armando López, Marina Martínez, Kirla R. Maurás-Rivera, Clarivel Lasalde, Daviana Martínez, Félix Araujo-Pérez & Carlos I. González. (2014) The Role of HuR in the Post-Transcriptional Regulation of Interleukin-3 in T Cells. PLoS ONE 9:3, pages e92457.
Crossref
John M. Kyriakis & Joseph Avruch. 2015. Encyclopedia of Inflammatory Diseases. Encyclopedia of Inflammatory Diseases 1 20 .
Sebastian Schulz, Anke Doller, Nicole R. Pendini, Jacqueline A. Wilce, Josef Pfeilschifter & Wolfgang Eberhardt. (2013) Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR. Cellular Signalling 25:12, pages 2485-2495.
Crossref
Ashley T. Neff, Carol J. Wilusz & Jeffrey Wilusz. 2006. Encyclopedia of Molecular Cell Biology and Molecular Medicine. Encyclopedia of Molecular Cell Biology and Molecular Medicine 1 26 .
Claude Lachance, Gabriella Wojewodka, Tom A. A. Skinner, Claudine Guilbault, Juan B. De Sanctis & Danuta Radzioch. (2013) Fenretinide Corrects the Imbalance between Omega-6 to Omega-3 Polyunsaturated Fatty Acids and Inhibits Macrophage Inflammatory Mediators via the ERK Pathway. PLoS ONE 8:9, pages e74875.
Crossref
Vito G. D’Agostino, Valentina Adami & Alessandro Provenzani. (2013) A Novel High Throughput Biochemical Assay to Evaluate the HuR Protein-RNA Complex Formation. PLoS ONE 8:8, pages e72426.
Crossref
Yanan Feng & Stanley N. Cohen. (2013) Upregulation of the Host SLC11A1 Gene by Clostridium difficile Toxin B Facilitates Glucosylation of Rho GTPases and Enhances Toxin Lethality. Infection and Immunity 81:8, pages 2724-2732.
Crossref
Roopa Thapar & Andria P. Denmon. (2013) Signaling pathways that control mRNA turnover. Cellular Signalling 25:8, pages 1699-1710.
Crossref
Anna S. Sahlberg, Marja Ruuska, Kaisa Granfors & Markus A. Penttinen. (2013) Altered Regulation of ELAVL1/HuR in HLA-B27–Expressing U937 Monocytic Cells. PLoS ONE 8:7, pages e70377.
Crossref
Robert B. Darnell. (2013) RNA Protein Interaction in Neurons. Annual Review of Neuroscience 36:1, pages 243-270.
Crossref
Christian Kroun Damgaard & Jens Lykke-Andersen. 2013. RNA and Cancer. RNA and Cancer 153 180 .
Kiyoshi Masuda, Yuki Kuwano, Kensei Nishida & Kazuhito Rokutan. 2013. Biological Aging. Biological Aging 285 308 .
Karim Belarbi, Timothy Jopson, David Tweedie, Carla Arellano, Weiming Luo, Nigel H Greig & Susanna Rosi. (2012) TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation. Journal of Neuroinflammation 9:1.
Crossref
John M. Kyriakis & Joseph Avruch. (2012) Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update. Physiological Reviews 92:2, pages 689-737.
Crossref
Jia-Xin Shi, Xin Su, Jin Xu, Wei-Yun Zhang & Yi Shi. (2012) HuR post-transcriptionally regulates TNF-α-induced IL-6 expression in human pulmonary microvascular endothelial cells mainly via tristetraprolin. Respiratory Physiology & Neurobiology 181:2, pages 154-161.
Crossref
Xiaotian Zhang, Zhenyun Liu, Jie Yi, Hao Tang, Junyue Xing, Minqwei Yu, Tanjun Tong, Yongfeng Shang, Myriam Gorospe & Wengong Wang. (2012) The tRNA methyltransferase NSun2 stabilizes p16INK4 mRNA by methylating the 3′-untranslated region of p16. Nature Communications 3:1.
Crossref
Nerea Bartolomé, Patricia Aspichueta, María J Martínez, Mercedes Vázquez-Chantada, María L Martínez-Chantar, Begoña Ochoa & Yolanda Chico. (2010) Biphasic adaptative responses in VLDL metabolism and lipoprotein homeostasis during Gram-negative endotoxemia. Innate Immunity 18:1, pages 89-99.
Crossref
Alessia Pascale & Stefano Govoni. (2011) The complex world of post-transcriptional mechanisms: is their deregulation a common link for diseases? Focus on ELAV-like RNA-binding proteins. Cellular and Molecular Life Sciences 69:4, pages 501-517.
Crossref
Jae-Kwan Kim, Sang-Min Lee, Kyoungho Suk & Won-Ha Lee. (2011) A Novel Pathway Responsible for Lipopolysaccharide-Induced Translational Regulation of TNF-α and IL-6 Expression Involves Protein Kinase C and Fascin. The Journal of Immunology 187:12, pages 6327-6334.
Crossref
Muthukumar Nadar, Meng-Yu Chan, Shi-Wei Huang, Chin-Cheng Huang, Joseph T Tseng & Ching-Hsiu Tsai. (2011) HuR binding to AU-rich elements present in the 3' untranslated region of Classical swine fever virus. Virology Journal 8:1.
Crossref
Joanna M. Clark, Karolina Aleksiyadis, Alex Martin, Kay McNamee, Tharsana Tharmalingam, Richard O. Williams, Sylvie Mémet & Andrew P. Cope. (2011) Inhibitor of Kappa B Epsilon (IκBε) Is a Non-Redundant Regulator of c-Rel-Dependent Gene Expression in Murine T and B Cells. PLoS ONE 6:9, pages e24504.
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Dorothea Pieper, Susann Schirmer, Alexander T. Prechtel, Ralph H. Kehlenbach, Joachim Hauber & Jan Chemnitz. (2011) Functional Characterization of the HuR:CD83 mRNA Interaction. PLoS ONE 6:8, pages e23290.
Crossref
Cristiana Stellato, Matthew M. Gubin, Joseph D. Magee, Xi Fang, Jinshui Fan, Danielle M. Tartar, Jing Chen, Garrett M. Dahm, Robert Calaluce, Francesca Mori, Glenn A. Jackson, Vincenzo Casolaro, Craig L. Franklin & Ulus Atasoy. (2011) Coordinate Regulation of GATA-3 and Th2 Cytokine Gene Expression by the RNA-Binding Protein HuR . The Journal of Immunology 187:1, pages 441-449.
Crossref
Natalia Filippova, Xiuhua Yang, Yimin Wang, G. Yancey Gillespie, Cathy Langford, Peter H. King, Crystal Wheeler & L. Burt Nabors. (2011) The RNA-Binding Protein HuR Promotes Glioma Growth and Treatment Resistance. Molecular Cancer Research 9:5, pages 648-659.
Crossref
Terry C.T. Or, Cindy L.H. Yang, Anna H.Y. Law, James C.B. Li & Allan S.Y. Lau. (2011) Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia. Neuropharmacology 60:6, pages 823-831.
Crossref
Yuki Fujiwara, Katsumi Kasashima, Kuniaki Saito, Miho Fukuda, Akira Fukao, Yumi Sasano, Kunio Inoue, Toshinobu Fujiwara & Hiroshi Sakamoto. (2011) Microtubule association of a neuronal RNA-binding protein HuD through its binding to the light chain of MAP1B. Biochimie 93:5, pages 817-822.
Crossref
L F ZNAMENSKAYA, YU YU YEGOROVA & S V ZITNER. (2011) Mechanism of the biological effect of the tumor necrosis factor-аlpha at psoriasis. Vestnik dermatologii i venerologii 87:2, pages 13-17.
Crossref
Reiko Sugiura, Ryosuke Satoh, Shunji Ishiwata, Nanae Umeda & Ayako Kita. (2011) Role of RNA-Binding Proteins in MAPK Signal Transduction Pathway. Journal of Signal Transduction 2011, pages 1-8.
Crossref
Jinshui Fan, Faoud T. Ishmael, Xi Fang, Allen Myers, Chris Cheadle, Shau-Ku Huang, Ulus Atasoy, Myriam Gorospe & Cristiana Stellato. (2011) Chemokine Transcripts as Targets of the RNA-Binding Protein HuR in Human Airway Epithelium. The Journal of Immunology 186:4, pages 2482-2494.
Crossref
Henry S. Kim, Matthew C. J. Wilce, Yano M. K. Yoga, Nicole R. Pendini, Menachem J. Gunzburg, Nathan P. Cowieson, Gerald M. Wilson, Bryan R. G. Williams, Myriam Gorospe & Jacqueline A. Wilce. (2011) Different modes of interaction by TIAR and HuR with target RNA and DNA. Nucleic Acids Research 39:3, pages 1117-1130.
Crossref
Anna Smerdel‐Ramoya, Stefano Zanotti & Ernesto Canalis. (2011) Nephroblastoma overexpressed (Nov) induces gremlin in ST‐2 stromal cell lines by post‐transcriptional mechanisms. Journal of Cellular Biochemistry 112:2, pages 715-722.
Crossref
Shashi Bala, Miguel Marcos, Karen Kodys, Timea Csak, Donna Catalano, Pranoti Mandrekar & Gyongyi Szabo. (2011) Up-regulation of MicroRNA-155 in Macrophages Contributes to Increased Tumor Necrosis Factor α (TNFα) Production via Increased mRNA Half-life in Alcoholic Liver Disease. Journal of Biological Chemistry 286:2, pages 1436-1444.
Crossref
Natalia Ronkina, Manoj B. Menon, Jessica Schwermann, Christopher Tiedje, Edward Hitti, Alexey Kotlyarov & Matthias Gaestel. (2010) MAPKAP kinases MK2 and MK3 in inflammation: Complex regulation of TNF biosynthesis via expression and phosphorylation of tristetraprolin. Biochemical Pharmacology 80:12, pages 1915-1920.
Crossref
Tarnjit K. Khera, Andrew D. Dick & Lindsay B. Nicholson. (2010) Mechanisms of TNFα regulation in uveitis: Focus on RNA-binding proteins. Progress in Retinal and Eye Research 29:6, pages 610-621.
Crossref
Fang Xu, Xiaotian Zhang, Yutao Lei, Xinwen Liu, Zhenyun Liu, Tanjun Tong & Wengong Wang. (2010) Loss of Repression of HuR Translation by miR‐16 May Be Responsible for the Elevation of HuR in Human Breast Carcinoma. Journal of Cellular Biochemistry 111:3, pages 727-734.
Crossref
Melissa D. LaJevic, Sujatha P. Koduvayur, Veronique Caffrey, Rhonna L. Cohen & Donald A. Chambers. (2010) Thy-1 mRNA destabilization by norepinephrine a 3′ UTR cAMP responsive decay element and involves RNA binding proteins. Brain, Behavior, and Immunity 24:7, pages 1078-1088.
Crossref
Francesco P. Marchese, Anna Aubareda, Corina Tudor, Jeremy Saklatvala, Andrew R. Clark & Jonathan L.E. Dean. (2010) MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment. Journal of Biological Chemistry 285:36, pages 27590-27600.
Crossref
Jaehyuk Yoo, Jinjoo Kang, Ha Neul Lee, Berenice Aguilar, Darren Kafka, Sunju Lee, Inho Choi, Juneyong Lee, Swapnika Ramu, Juergen Haas, Chester J. Koh & Young-Kwon Hong. (2010) Kaposin-B Enhances the PROX1 mRNA Stability during Lymphatic Reprogramming of Vascular Endothelial Cells by Kaposi's Sarcoma Herpes Virus. PLoS Pathogens 6:8, pages e1001046.
Crossref
Tarnjit K. Khera, Andrew D. Dick & Lindsay B. Nicholson. (2010) Fragile X‐related protein FXR1 controls post‐transcriptional suppression of lipopolysaccharide‐induced tumour necrosis factor‐α production by transforming growth factor‐β1. The FEBS Journal 277:13, pages 2754-2765.
Crossref
Mohamed El Gazzar & Charles E. McCall. (2010) MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance. Journal of Biological Chemistry 285:27, pages 20940-20951.
Crossref
Deborah J. Stumpo, Wi S. Lai & Perry J. Blackshear. (2010) Inflammation: cytokines and RNA‐based regulation. WIREs RNA 1:1, pages 60-80.
Crossref
Huei-Ting Yang, Mark Peggie, Philip Cohen & Simon Rousseau. (2009) DAZAP1 interacts via its RNA-recognition motifs with the C-termini of other RNA-binding proteins. Biochemical and Biophysical Research Communications 380:3, pages 705-709.
Crossref
Tae-Don KimJu Yeong ParkInpyo Choi. (2009) Post-transcriptional Regulation of NK Cell Activation. Immune Network 9:4, pages 115.
Crossref
Min-Ju ChaeHye Youn SungEun-Hye KimMira LeeHojoong KwakChong Hak ChaeSunwoo KimWoong-Yang Park. (2009) Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-α mRNA. Experimental and Molecular Medicine 41:11, pages 824.
Crossref
Timothy T. Cornell & Thomas P. Shanley. 2009. Science and Practice of Pediatric Critical Care Medicine. Science and Practice of Pediatric Critical Care Medicine 1 9 .
Anke Doller, Josef Pfeilschifter & Wolfgang Eberhardt. (2008) Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. Cellular Signalling 20:12, pages 2165-2173.
Crossref
Jodi M. Saunus, Juliet D. French, Stacey L. Edwards, Dianne J. Beveridge, Esme C. Hatchell, Sarah A. Wagner, Sandra R. Stein, Andrew Davidson, Kaylene J. Simpson, Glenn D. Francis, Peter J. Leedman & Melissa A. Brown. (2008) Posttranscriptional Regulation of the Breast Cancer Susceptibility Gene BRCA1 by the RNA Binding Protein HuR . Cancer Research 68:22, pages 9469-9478.
Crossref
Joy Cherry, Heath Jones, Vesna A. Karschner & Phillip H. Pekala. (2008) Post-transcriptional Control of CCAAT/Enhancer-binding Protein β (C/EBPβ) Expression. Journal of Biological Chemistry 283:45, pages 30812-30820.
Crossref
Gaelle Kustermans, Nadia El Mjiyad, Julie Horion, Nathalie Jacobs, Jacques Piette & Sylvie Legrand-Poels. (2008) Actin cytoskeleton differentially modulates NF-κB-mediated IL-8 expression in myelomonocytic cells. Biochemical Pharmacology 76:10, pages 1214-1228.
Crossref
Pil-Hoon Park, Honglian Huang, Megan R. McMullen, Palash Mandal, Lei Sun & Laura E. Nagy. (2008) Suppression of Lipopolysaccharide-stimulated Tumor Necrosis Factor-α Production by Adiponectin Is Mediated by Transcriptional and Post-transcriptional Mechanisms. Journal of Biological Chemistry 283:40, pages 26850-26858.
Crossref
Vaishali R. Moulton, Vasileios C. Kyttaris, Yuang-Taung Juang, Bhabadeb Chowdhury & George C. Tsokos. (2008) The RNA-stabilizing Protein HuR Regulates the Expression of ζ Chain of the Human T Cell Receptor-associated CD3 Complex. Journal of Biological Chemistry 283:29, pages 20037-20044.
Crossref
Vincenzo Casolaro, Xi Fang, Brian Tancowny, Jinshui Fan, Fan Wu, Subramanya Srikantan, S. Yukiko Asaki, Umberto De Fanis, Shau-Ku Huang, Myriam Gorospe, Ulus X. Atasoy & Cristiana Stellato. (2008) Posttranscriptional regulation of IL-13 in T cells: Role of the RNA-binding protein HuR. Journal of Allergy and Clinical Immunology 121:4, pages 853-859.e4.
Crossref
Kotb Abdelmohsen, Yuki Kuwano, Hyeon Ho Kim & Myriam Gorospe. (2008) Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. bchm 389:3, pages 243-255.
Crossref
Claire L. Gorman, Andrew I. Russell, Zhuoli Zhang, Deborah Cunninghame Graham, Andrew P. Cope & Timothy J. Vyse. (2008) Polymorphisms in the CD3Z Gene Influence TCRζ Expression in Systemic Lupus Erythematosus Patients and Healthy Controls . The Journal of Immunology 180:2, pages 1060-1070.
Crossref
Jason M. Gow, Leslie W. Chinn & Deanna L. Kroetz. (2008) The Effects of ABCB1 3′-Untranslated Region Variants on mRNA Stability . Drug Metabolism and Disposition 36:1, pages 10-15.
Crossref
Kristen M. Deleault, Stephen J. Skinner & Seth A. Brooks. (2008) Tristetraprolin regulates TNF TNF-α mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways. Molecular Immunology 45:1, pages 13-24.
Crossref
Miguel A. Rodríguez-Gabriel & Paul Russell. 2008. Stress-Activated Protein Kinases. Stress-Activated Protein Kinases 159 170 .
R.N. Morrison, J. Zou, C.J. Secombes, G. Scapigliati, M.B. Adams & B.F. Nowak. (2007) Molecular cloning and expression analysis of tumour necrosis factor-α in amoebic gill disease (AGD)-affected Atlantic salmon (Salmo salar L.). Fish & Shellfish Immunology 23:5, pages 1015-1031.
Crossref
Esmerina Tili, Jean-Jacques Michaille, Amelia Cimino, Stefan Costinean, Calin Dan Dumitru, Brett Adair, Muller Fabbri, Hannes Alder, Chang Gong Liu, George Adrian Calin & Carlo Maria Croce. (2007) Modulation of miR-155 and miR-125b Levels following Lipopolysaccharide/TNF-α Stimulation and Their Possible Roles in Regulating the Response to Endotoxin Shock. The Journal of Immunology 179:8, pages 5082-5089.
Crossref
Pamela S. David, Rasheeda Tanveer & J. David Port. (2007) FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1. RNA 13:9, pages 1453-1468.
Crossref
Ashish Banerjee & Steve Gerondakis. (2007) Coordinating TLR‐activated signaling pathways in cells of the immune system. Immunology & Cell Biology 85:6, pages 420-424.
Crossref
Nicole-Claudia Meisner, Martin Hintersteiner, Kurt Mueller, Roman Bauer, Jan-Marcus Seifert, Hans-Ulrich Naegeli, Johannes Ottl, Lukas Oberer, Christian Guenat, Serge Moss, Nathalie Harrer, Maximilian Woisetschlaeger, Christof Buehler, Volker Uhl & Manfred Auer. (2007) Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nature Chemical Biology 3:8, pages 508-515.
Crossref
Elizabeth J. Fialcowitz-White, Brandy Y. Brewer, Jeff D. Ballin, Chris D. Willis, Eric A. Toth & Gerald M. Wilson. (2007) Specific Protein Domains Mediate Cooperative Assembly of HuR Oligomers on AU-rich mRNA-destabilizing Sequences. Journal of Biological Chemistry 282:29, pages 20948-20959.
Crossref
Makoto Sugihara, Akito Tsutsumi, Eiji Suzuki, Ei Wakamatsu, Takeshi Suzuki, Hiroshi Ogishima, Taichi Hayashi, Yusuke Chino, Wataru Ishii, Mizuko Mamura, Daisuke Goto, Isao Matsumoto, Satoshi Ito & Takayuki Sumida. (2007) Effects of infliximab therapy on gene expression levels of tumor necrosis factor α, tristetraprolin, T cell intracellular antigen 1, and Hu antigen R in patients with rheumatoid arthritis. Arthritis & Rheumatism 56:7, pages 2160-2169.
Crossref
Xiaoyan Dai, Xiang Ou, Xinrui Hao, Dongli Cao, Yaling Tang, Yanwei Hu, Xiaoxu Li & Chaoke Tang. (2007) Effect of T0901317 on Hepatic Proinflammatory Gene Expression in ApoE−/− Mice Fed a High-fat/high-cholesterol Diet. Inflammation 30:3-4, pages 105-117.
Crossref
Wolfgang Eberhardt, Anke Doller, El-Sayed Akool & Josef Pfeilschifter. (2007) Modulation of mRNA stability as a novel therapeutic approach. Pharmacology & Therapeutics 114:1, pages 56-73.
Crossref
Feng-Yen LinYung-Hsiang ChenYi-Wen LinJen-Sung TsaiJaw-Wen ChenHsiao-Jung WangYuh-Lien ChenChi-Yuan LiShing-Jong Lin. (2006) The Role of Human Antigen R, an RNA-binding Protein, in Mediating the Stabilization of Toll-Like Receptor 4 mRNA Induced by Endotoxin. Arteriosclerosis, Thrombosis, and Vascular Biology 26:12, pages 2622-2629.
Crossref
Selvi C. Jeyaraj, Duaa Dakhlallah, Stephanie R. Hill & Beth S. Lee. (2006) Expression and distribution of HuR during ATP depletion and recovery in proximal tubule cells. American Journal of Physiology-Renal Physiology 291:6, pages F1255-F1263.
Crossref
Marisa M. O. Tschernatsch, Bernhard Mlecnik, Zlatko Trajanoski, Rudolf Zechner & Robert Zimmermann. (2006) LPL-mediated lipolysis of VLDL induces an upregulation of AU-rich mRNAs and an activation of HuR in endothelial cells. Atherosclerosis 189:2, pages 310-317.
Crossref
Sheng-Ru Shiou, Pran K. Datta, Punita Dhawan, Brian K. Law, Jonathan M. Yingling, Dan A. Dixon & R. Daniel Beauchamp. (2006) Smad4-dependent Regulation of Urokinase Plasminogen Activator Secretion and RNA Stability Associated with Invasiveness by Autocrine and Paracrine Transforming Growth Factor-β. Journal of Biological Chemistry 281:45, pages 33971-33981.
Crossref
Simon MortonHuei-Ting YangNtsane MolelekiDavid G. CampbellPhilip CohenSimon Rousseau. (2006) Phosphorylation of the ARE-binding protein DAZAP1 by ERK2 induces its dissociation from DAZ. Biochemical Journal 399:2, pages 265-273.
Crossref
Naoshi Fukui, Yasuko Ikeda, Toshiyuki Ohnuki, Atsuhiko Hikita, Sakae Tanaka, Shoji Yamane, Ryuji Suzuki, Linda J. Sandell & Takahiro Ochi. (2006) Pro-inflammatory Cytokine Tumor Necrosis Factor-α Induces Bone Morphogenetic Protein-2 in Chondrocytes via mRNA Stabilization and Transcriptional Up-regulation. Journal of Biological Chemistry 281:37, pages 27229-27241.
Crossref
Carine Barreau, Tanguy Watrin, H. Beverley Osborne & Luc Paillard. (2006) Protein expression is increased by a class III AU-rich element and tethered CUG-BP1. Biochemical and Biophysical Research Communications 347:3, pages 723-730.
Crossref
Yu-Ling Chen, Ya-Lin Huang, Nien-Yi Lin, Hui-Chen Chen, Wan-Chih Chiu & Ching-Jin Chang. (2006) Differential regulation of ARE-mediated TNFα and IL-1β mRNA stability by lipopolysaccharide in RAW264.7 cells. Biochemical and Biophysical Research Communications 346:1, pages 160-168.
Crossref
Hiroki Nagoshi, Hiroyuki Inagawa, Kayoko Morii, Hideaki Harada, Chie Kohchi, Takashi Nishizawa, Yoshie Taniguchi, Maya Uenobe, Teruko Honda, Masakazu Kondoh, Yukinori Takahashi & Gen-Ichiro Soma. (2006) Cloning and characterization of a LPS-regulatory gene having an LPS binding domain in kuruma prawn Marsupenaeus japonicus. Molecular Immunology 43:13, pages 2061-2069.
Crossref
Nadia Cherradi, Cyrille Lejczak, Agnes Desroches-Castan & Jean-Jacques Feige. (2006) Antagonistic Functions of Tetradecanoyl Phorbol Acetate-Inducible-Sequence 11b and HuR in the Hormonal Regulation of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Stability by Adrenocorticotropin. Molecular Endocrinology 20:4, pages 916-930.
Crossref
Kentaro Nagaoka, Toshiyuki Suzuki, Tomomi Kawano, Kazuhiko Imakawa & Senkiti Sakai. (2006) Stability of casein mRNA is ensured by structural interactions between the 3′-untranslated region and poly(A) tail via the HuR and poly(A)-binding protein complex. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1759:3-4, pages 132-140.
Crossref
Peter W. Szlosarek, Matthew J. Grimshaw, Hagen Kulbe, Julia L. Wilson, George D. Wilbanks, Frances Burke & Frances R. Balkwill. (2006) Expression and regulation of tumor necrosis factor α in normal and malignant ovarian epithelium. Molecular Cancer Therapeutics 5:2, pages 382-390.
Crossref
Britt A. Glaunsinger & Donald E. Ganem. 2006. 337 394 .
Juliana L. Blum, Allen M. Samarel & Ruben Mestril. (2005) Phosphorylation and binding of AUF1 to the 3′-untranslated region of cardiomyocyte SERCA2a mRNA. American Journal of Physiology-Heart and Circulatory Physiology 289:6, pages H2543-H2550.
Crossref
Cara J Westmark, Françoise A Gourronc, Virginia B Bartleson, Ümit Sayin, Saswati Bhattacharya, Tom Sutula & James S Malter. (2005) HuR mRNA Ligands Expressed After Seizure. Journal of Neuropathology and Experimental Neurology 64:12, pages 1037-1045.
Crossref
Gentzon Hall, Ishwar S. Singh, Lisa Hester, Jeffery D. Hasday & Terry B. Rogers. (2005) Inhibitor-κB kinase-β regulates LPS-induced TNF-α production in cardiac myocytes through modulation of NF-κB p65 subunit phosphorylation. American Journal of Physiology-Heart and Circulatory Physiology 289:5, pages H2103-H2111.
Crossref
Vicky Katsanou, Olympia Papadaki, Stavros Milatos, Perry J. Blackshear, Paul Anderson, George Kollias & Dimitris L. Kontoyiannis. (2005) HuR as a Negative Posttranscriptional Modulator in Inflammation. Molecular Cell 19:6, pages 777-789.
Crossref
Davy C. W. Lee, Chung-Yan Cheung, Anna H. Y. Law, Chris K. P. Mok, Malik Peiris & Allan S. Y. Lau. (2005) p38 Mitogen-Activated Protein Kinase-Dependent Hyperinduction of Tumor Necrosis Factor Alpha Expression in Response to Avian Influenza Virus H5N1. Journal of Virology 79:16, pages 10147-10154.
Crossref
Helen JL Speirs, William YS Wang, Adam V Benjafield & Brian J Morris. (2005) No association with hypertension of CLCNKB and TNFRSF1B polymorphisms at a hypertension locus on chromosome 1p36. Journal of Hypertension 23:8, pages 1491-1496.
Crossref
Im-Sook Song, Shigeru Tatebe, Wenping Dai & M. Tien Kuo. (2005) Delayed Mechanism for Induction of γ-Glutamylcysteine Synthetase Heavy Subunit mRNA Stability by Oxidative Stress Involving p38 Mitogen-activated Protein Kinase Signaling. Journal of Biological Chemistry 280:31, pages 28230-28240.
Crossref
Mortimer Korf, Dominik Jarczak, Carmela Beger, Michael P. Manns & Martin Krüger. (2005) Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors. Journal of Hepatology 43:2, pages 225-234.
Crossref
Stephen D. Wax, Hideki Nakamura & Paul J. Anderson. (2005) The tumor necrosis factor-α AU-rich element inhibits the stable association of the 40S ribosomal subunit with RNA transcripts. Biochemical and Biophysical Research Communications 333:4, pages 1100-1106.
Crossref
James Garnon, Claude Lachance, Sergio Di Marco, Zdenek Hel, Dominique Marion, Maria C. Ruiz, Marianna M. Newkirk, Edouard W. Khandjian & Danuta Radzioch. (2005) Fragile X-related Protein FXR1P Regulates Proinflammatory Cytokine Tumor Necrosis Factor Expression at the Post-transcriptional Level. Journal of Biological Chemistry 280:7, pages 5750-5763.
Crossref
Yoshikuni Nagamine, Robert L. Medcalf & Pura Muñoz-Cánoves. (2017) Transcriptional and posttranscriptional regulation of the plasminogen activator system. Thrombosis and Haemostasis 93:04, pages 661-675.
Crossref
Khalid S.A. Khabar. (2005) The AU-Rich Transcriptome: More Than Interferons and Cytokines, and Its Role in Disease. Journal of Interferon & Cytokine Research 25:1, pages 1-10.
Crossref
Soh Yamazaki, Tatsushi Muta, Susumu Matsuo & Koichiro Takeshige. (2005) Stimulus-specific Induction of a Novel Nuclear Factor-κB Regulator, IκB-ζ, via Toll/Interleukin-1 Receptor Is Mediated by mRNA Stabilization. Journal of Biological Chemistry 280:2, pages 1678-1687.
Crossref
Stan Stasinopoulos, Hoanh Tran, Emily Chen, Mythily Sachchithananthan, Yoshikuni Nagamine & Robert L. Medcalf. 2005. 169 215 .
Arvind Raghavan, Mohammed Dhalla, Tala Bakheet, Rachel L. Ogilvie, Irina A. Vlasova, Khalid S.A. Khabar, Bryan R.G. Williams & Paul R. Bohjanen. (2004) Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation. Genomics 84:6, pages 1002-1013.
Crossref
Sébastien Lahousse, Anne-Lise Smorowski, Claude Denis, Danièle Lantoine, Jean-Pierre Kerckaert & Sylvie Galiègue-Zouitina. (2004) Structural features of hematopoiesis-specific RhoH/ARHH gene: high diversity of 5′-UTR in different hematopoietic lineages suggests a complex post-transcriptional regulation. Gene 343:1, pages 55-68.
Crossref
Paul N. Tasker, Omar M. E. Albagha, Clifford B. Masson, David M. Reid & Stuart H. Ralston. (2004) Association between TNFRSF1B polymorphisms and bone mineral density, bone loss and fracture. Osteoporosis International 15:11, pages 903-908.
Crossref
Nicole‐Claudia Meisner, Jörg Hackermüller, Volker Uhl, András Aszódi, Markus Jaritz & Manfred Auer. (2004) mRNA Openers and Closers: Modulating AU‐Rich Element‐Controlled mRNA Stability by a Molecular Switch in mRNA Secondary Structure. ChemBioChem 5:10, pages 1432-1447.
Crossref
Jonathan L.E Dean, Gareth Sully, Andrew R Clark & Jeremy Saklatvala. (2004) The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation. Cellular Signalling 16:10, pages 1113-1121.
Crossref
Yukitomo Arao, Atsumi Kikuchi, Mitsuyo Kishida, Masami Yonekura, Akira Inoue, Shigemitsu Yasuda, Seiki Wada, Kazuhiro Ikeda & Fujio Kayama. (2004) Stability of A+U-Rich Element Binding Factor 1 (AUF1)-Binding Messenger Ribonucleic Acid Correlates with the Subcellular Relocalization of AUF1 in the Rat Uterus upon Estrogen Treatment. Molecular Endocrinology 18:9, pages 2255-2267.
Crossref
Yuko Seko, Hooman Azmi, Robert Fariss & Jack A. Ragheb. (2004) Selective Cytoplasmic Translocation of HuR and Site-specific Binding to the Interleukin-2 mRNA Are Not Sufficient for CD28-mediated Stabilization of the mRNA. Journal of Biological Chemistry 279:32, pages 33359-33367.
Crossref
Laura E. Nagy. (2004) Stabilization of tumor necrosis factor-alpha mRNA in macrophages in response to chronic ethanol exposure. Alcohol 33:3, pages 229-233.
Crossref
Jin-Yu Lu & Robert J. Schneider. (2004) Tissue Distribution of AU-rich mRNA-binding Proteins Involved in Regulation of mRNA Decay. Journal of Biological Chemistry 279:13, pages 12974-12979.
Crossref
Sheila Rydziel, Anne M. Delany & Ernesto Canalis. (2004) AU-Rich Elements in the Collagenase 3 mRNA Mediate Stabilization of the Transcript by Cortisol in Osteoblasts. Journal of Biological Chemistry 279:7, pages 5397-5404.
Crossref
Tsutomu YAKEUCHI & Kouichi AMANO. (2004) Anti-TNF therapy in rheumor arthritis新しい生物学的製剤を用いた難治性免疫疾患の治療　　ＴＮＦ阻害による関節リウマチの治療. Japanese Journal of Clinical Immunology 27:1, pages 7-15.
Crossref
Leh-Miauh Buu, Li-Ting Jang & Fang-Jen S. Lee. (2004) The Yeast RNA-binding Protein Rbp1p Modifies the Stability of Mitochondrial Porin mRNA. Journal of Biological Chemistry 279:1, pages 453-462.
Crossref
N-S Yang, J-H Wang & J Turner. (2003) Molecular strategies for improving cytokine transgene expression in normal and malignant tissues. Gene Therapy 11:1, pages 100-108.
Crossref
J.-C. Twizere, V. Kruys, L. Lefebvre, A. Vanderplasschen, D. Collete, C. Debacq, W. S. Lai, J.-C. Jauniaux, L. R. Bernstein, O. J. Semmes, A. Burny, P. J. Blackshear, R. Kettmann & L. Willems. (2003) Interaction of Retroviral Tax Oncoproteins With Tristetraprolin and Regulation of Tumor Necrosis Factor-  Expression. JNCI Journal of the National Cancer Institute 95:24, pages 1846-1859.
Crossref
Angels Navarro, Mathias Frevel, Ana M. Gamero, Bryan R.G. Williams, Gerald Feldman & Andrew C. Larner. (2003) Thrombomodulin RNA Is Destabilized Through Its 3′-Untranslated Element in Cells Exposed to IFN-γ. Journal of Interferon & Cytokine Research 23:12, pages 723-728.
Crossref
Andrea Huwiler, El-Sayed Akool, Armaz Aschrafi, Farid M.A. Hamada, Josef Pfeilschifter & Wolfgang Eberhardt. (2003) ATP Potentiates Interleukin-1β-induced MMP-9 Expression in Mesangial Cells via Recruitment of the ELAV Protein HuR. Journal of Biological Chemistry 278:51, pages 51758-51769.
Crossref
Guntram A. Grassl, Michael Kracht, Agnes Wiedemann, Elke Hoffmann, Martin Aepfelbacher, Christoph von Eichel-Streiber, Erwin Bohn & Ingo B. Autenrieth. (2003) Activation of NF-kappaB and IL-8 by Yersinia enterocolitica invasin protein is conferred by engagement of Rac1 and MAP kinase cascades. Cellular Microbiology 5:12, pages 957-971.
Crossref
Yong-Joo Chung, Hui-Ren Zhou & James J Pestka. (2003) Transcriptional and posttranscriptional roles for p38 mitogen-activated protein kinase in upregulation of TNF-α expression by deoxynivalenol (vomitoxin). Toxicology and Applied Pharmacology 193:2, pages 188-201.
Crossref
Sungmin Park-Lee, Soyoun Kim & Ite A. Laird-Offringa. (2003) Characterization of the Interaction between Neuronal RNA-binding Protein HuD and AU-rich RNA. Journal of Biological Chemistry 278:41, pages 39801-39808.
Crossref
Jonathan L.E. Dean, Simon J. Sarsfield, Elizabeth Tsounakou & Jeremy Saklatvala. (2003) p38 Mitogen-activated Protein Kinase Stabilizes mRNAs That Contain Cyclooxygenase-2 and Tumor Necrosis Factor AU-rich Elements by Inhibiting Deadenylation. Journal of Biological Chemistry 278:41, pages 39470-39476.
Crossref
Megan R. McMullen, Enzo Cocuzzi, Maria Hatzoglou & Laura E. Nagy. (2003) Chronic Ethanol Exposure Increases the Binding of HuR to the TNFα 3′-Untranslated Region in Macrophages. Journal of Biological Chemistry 278:40, pages 38333-38341.
Crossref
Sumita Bandyopadhyay, Tapas K Sengupta, Daniel J Fernandes & Eleanor K Spicer. (2003) Taxol- and okadaic acid-induced destabilization of bcl-2 mRNA is associated with decreased binding of proteins to a bcl-2 instability element. Biochemical Pharmacology 66:7, pages 1151-1162.
Crossref
Martha M. Monick, Linda S. Powers, Noah S. Butler & Gary W. Hunninghake. (2003) Inhibition of Rho Family GTPases Results in Increased TNF-α Production After Lipopolysaccharide Exposure. The Journal of Immunology 171:5, pages 2625-2630.
Crossref
Shigeki Bamba, Akira Andoh, Hirofumi Yasui, Jin Makino, Shokei Kim & Yoshihide Fujiyama. (2003) Regulation of IL-11 expression in intestinal myofibroblasts: role of c-Jun AP-1- and MAPK-dependent pathways. American Journal of Physiology-Gastrointestinal and Liver Physiology 285:3, pages G529-G538.
Crossref
Steven J. Cok, Stephen J. Acton & Aubrey R. Morrison. (2003) The Proximal Region of the 3′-Untranslated Region of Cyclooxygenase-2 is Recognized by a Multimeric Protein Complex Containing HuR, TIA-1, TIAR, and the Heterogeneous Nuclear Ribonucleoprotein U. Journal of Biological Chemistry 278:38, pages 36157-36162.
Crossref
Andrew R. Clark, Jonathan L.E. Dean & Jeremy Saklatvala. (2003) Post‐transcriptional regulation of gene expression by mitogen‐activated protein kinase p38. FEBS Letters 546:1, pages 37-44.
Crossref
Sibani Sengupta, Byeong-Churl Jang, Ming-Tao Wu, Ji-Hye Paik, Henry Furneaux & Timothy Hla. (2003) The RNA-binding Protein HuR Regulates the Expression of Cyclooxygenase-2. Journal of Biological Chemistry 278:27, pages 25227-25233.
Crossref
Koichiro Sakai, Yoko Kitagawa, Misuzu Saiki, Shinji Saiki & Genjiro Hirose. (2003) Binding of the ELAV-like protein in murine autoimmune T-cells to the nonameric AU-rich element in the 3′ untranslated region of CD154 mRNA. Molecular Immunology 39:14, pages 879-883.
Crossref
Baiya Krishnadasan, Babu V. Naidu, Karen Byrne, Charles Fraga, Edward D. Verrier & Michael S. Mulligan. (2003) The role of proinflammatory cytokines in lung ischemia-reperfusion injury. The Journal of Thoracic and Cardiovascular Surgery 125:2, pages 261-272.
Crossref
Robert Newton & Neil Holden. (2003) Inhibitors of p38 Mitogen-Activated Protein Kinase. BioDrugs 17:2, pages 113-129.
Crossref
Wei Shen, Dianna Willis, Yanping Zhang & George R. Molloy. (2003) Expression of Creatine Kinase Isoenzyme Genes during Postnatal Development of Rat Brain Cerebrum: Evidence for Posttranscriptional Regulation. Developmental Neuroscience 25:6, pages 421-435.
Crossref

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