Search in:

Molecular and Cellular Biology Volume 21, 2001 - Issue 8

Views

CrossRef citations to date

Altmetric

Gene Expression

Reduction of Target Gene Expression by a Modified U1 snRNA

S. A. Beckley1 Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut06030

P. Liu1 Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut06030

M. L. Stover1 Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut06030

S. I. Gunderson2 Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, New Jersey08854

A. C. Lichtler1 Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut06030

D. W. Rowe1 Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut06030Correspondence[email protected]

Pages 2815-2825 | Received 03 Aug 2000, Accepted 17 Jan 2001, Published online: 28 Mar 2023

Cite this article
https://doi.org/10.1128/MCB.21.8.2815-2825.2001

Full Article
Figures & data
References
Citations
Metrics
Reprints & Permissions

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Articles from other publishers (33)

Jamie Nourse, Stefano Spada & Sven Danckwardt. (2020) Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders. Biomolecules 10:6, pages 915.
Crossref

Benjamin Strobel, Maike Spöring, Holger Klein, Dragica Blazevic, Werner Rust, Sergi Sayols, Jörg S. Hartig & Sebastian Kreuz. (2020) High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells. Nature Communications 11:1.
Crossref

Esther Braselmann, Aleksandra J. Wierzba, Jacob T. Polaski, Mikołaj Chromiński, Zachariah E. Holmes, Sheng-Ting Hung, Dilara Batan, Joshua R Wheeler, Roy Parker, Ralph Jimenez, Dorota Gryko, Robert T. Batey & Amy E. Palmer. (2018) A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells. Nature Chemical Biology 14:10, pages 964-971.
Crossref

Daisuke Kaida. (2016) The reciprocal regulation between splicing and 3′‐end processing. WIREs RNA 7:4, pages 499-511.
Crossref

Manuela S. Pieperhoff, Gurman S. Pall, Elena Jiménez-Ruiz, Sujaan Das, Carmen Melatti, Matthew Gow, Eleanor H. Wong, Joanne Heng, Sylke Müller, Michael J. Blackman & Markus Meissner. (2015) Conditional U1 Gene Silencing in Toxoplasma gondii. PLOS ONE 10:6, pages e0130356.
Crossref

Lorea Blázquez & Puri Fortes. 2015. Gene Therapy for HIV and Chronic Infections. Gene Therapy for HIV and Chronic Infections 51 69 .

Siddharth Shukla & Roy Parker. (2014) Quality control of assembly-defective U1 snRNAs by decapping and 5′-to-3′ exonucleolytic digestion. Proceedings of the National Academy of Sciences 111:32.
Crossref

Anders Rehfeld, Mireya Plass, Kristina DÃ¸ssing, Ulrich Knigge, Andreas KjÃ¦r, Anders Krogh & Lennart Friis-Hansen. (2014) Alternative Polyadenylation of Tumor Suppressor Genes in Small Intestinal Neuroendocrine Tumors. Frontiers in Endocrinology 5.
Crossref

Yusaku Kikuchi, Naoshi Yamazaki, Noriko Tarashima, Kazuhiro Furukawa, Yoshiharu Takiguchi, Kohji Itoh & Noriaki Minakawa. (2013) Gene suppression via U1 small nuclear RNA interference (U1i) machinery using oligonucleotides containing 2′-modified-4′-thionucleosides. Bioorganic & Medicinal Chemistry 21:17, pages 5292-5296.
Crossref

Ulrike WeirauchArnold GrünwellerLuis CuellarRoland K. HartmannAchim Aigner. (2013) U1 Adaptors for the Therapeutic Knockdown of the Oncogene Pim-1 Kinase in Glioblastoma. Nucleic Acid Therapeutics 23:4, pages 264-272.
Crossref

Lee Spraggon & Luca Cartegni. (2013) U1 snRNP-Dependent Suppression of Polyadenylation: Physiological Role and Therapeutic Opportunities in Cancer. International Journal of Cell Biology 2013, pages 1-10.
Crossref

Steven West. (2012) The increasing functional repertoire of U1 snRNA. Biochemical Society Transactions 40:4, pages 846-849.
Crossref

Eugenio Fernandez Alanis, Mirko Pinotti, Andrea Dal Mas, Dario Balestra, Nicola Cavallari, Malgorzata E. Rogalska, Francesco Bernardi & Franco Pagani. (2012) An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects. Human Molecular Genetics 21:11, pages 2389-2398.
Crossref

Stefanie A. Knoepfel, Amaya Abad, Xabi Abad, Puri Fortes & Ben Berkhout. (2012) Design of modified U1i molecules against HIV-1 RNA. Antiviral Research 94:3, pages 208-216.
Crossref

Lorea Blazquez, Sandra Jovanna Gonzalez-Rojas, Amaya Abad, Nerea Razquin, Xabier Abad & Puri Fortes. (2012) Increased in vivo inhibition of gene expression by combining RNA interference and U1 inhibition. Nucleic Acids Research 40:1, pages e8-e8.
Crossref

M. PINOTTI, F. BERNARDI, A. DAL MAS & F. PAGANI. (2011) RNA‐based therapeutic approaches for coagulation factor deficiencies. Journal of Thrombosis and Haemostasis 9:11, pages 2143-2152.
Crossref

A Koornneef, R van Logtenstein, E Timmermans, L Pisas, B Blits, X Abad, P Fortes, H Petry, P Konstantinova & T Ritsema. (2011) AAV-mediated in vivo knockdown of luciferase using combinatorial RNAi and U1i. Gene Therapy 18:9, pages 929-935.
Crossref

Dibyakanti Mandal, Zehua Feng & C. Martin Stoltzfus. (2010) Excessive RNA Splicing and Inhibition of HIV-1 Replication Induced by Modified U1 Small Nuclear RNAs. Journal of Virology 84:24, pages 12790-12800.
Crossref

X. Abad, N. Razquin, A. Abad & P. Fortes. (2010) Combination of RNA interference and U1 inhibition leads to increased inhibition of gene expression. Nucleic Acids Research 38:13, pages e136-e136.
Crossref

Krzysztof Wypijewski, Csaba Hornyik, Jane A. Shaw, Jennifer Stephens, Rafal Goraczniak, Samuel I. Gunderson & Christophe Lacomme. (2009) Ectopic 5′ Splice Sites Inhibit Gene Expression by Engaging RNA Surveillance and Silencing Pathways in Plants . Plant Physiology 151:2, pages 955-965.
Crossref

Arnold Grünweller & Roland K. Hartmann. (2009) Expanding RNA Silencing Approaches by U1 Adaptors. ChemBioChem 10:10, pages 1599-1601.
Crossref

Rafal Goraczniak, Mark A Behlke & Samuel I Gunderson. (2009) Gene silencing by synthetic U1 Adaptors. Nature Biotechnology 27:3, pages 257-263.
Crossref

Xabi Abad, Maria Vera, Stephen P. Jung, Evelyn Oswald, Inés Romero, Vaibhav Amin, Puri Fortes & Samuel I. Gunderson. (2008) Requirements for gene silencing mediated by U1 snRNA binding to a target sequence. Nucleic Acids Research 36:7, pages 2338-2352.
Crossref

Rafal Goraczniak & Samuel I. Gunderson. (2008) The Regulatory Element in the 3′-Untranslated Region of Human Papillomavirus 16 Inhibits Expression by Binding CUG-binding Protein 1. Journal of Biological Chemistry 283:4, pages 2286-2296.
Crossref

David W. Rowe. 2008. Principles of Bone Biology. Principles of Bone Biology 1511 1531 .

Fei Guan, Rose M. Caratozzolo, Rafal Goraczniak, Eric S. Ho & Samuel I. Gunderson. (2007) A bipartite U1 site represses U1A expression by synergizing with PIE to inhibit nuclear polyadenylation. RNA 13:12, pages 2129-2140.
Crossref

Jianming Qiu & David J. Pintel. (2004) Alternative Polyadenylation of Adeno-associated Virus Type 5 RNA within an Internal Intron Is Governed by the Distance between the Promoter and the Intron and Is Inhibited by U1 Small Nuclear RNP Binding to the Intervening Donor. Journal of Biological Chemistry 279:15, pages 14889-14898.
Crossref

Kirk M Brown & Gregory M Gilmartin. (2003) A Mechanism for the Regulation of Pre-mRNA 3′ Processing by Human Cleavage Factor Im. Molecular Cell 12:6, pages 1467-1476.
Crossref

Puri Fortes, Yolanda Cuevas, Fei Guan, Peng Liu, Sara Pentlicky, Stephen P. Jung, Maria L. Martínez-Chantar, Jesús Prieto, David Rowe & Samuel I. Gunderson. (2003) Inhibiting expression of specific genes in mammalian cells with 5′ end-mutated U1 small nuclear RNAs targeted to terminal exons of pre-mRNA. Proceedings of the National Academy of Sciences 100:14, pages 8264-8269.
Crossref

J.M Sierra-Montes, S Pereira-Simon, A.V Freund, L.M Ruiz, M.N Szmulewicz & R.J Herrera. (2003) A diversity of U1 small nuclear RNAs in the silk moth Bombyx mori. Insect Biochemistry and Molecular Biology 33:1, pages 29-39.
Crossref

HORACIO PLOTKIN, DRAGAN PRIMORAC & DAVID ROWE. 2003. Pediatric Bone. Pediatric Bone 443 X .

Roger Abounader, Bachchu Lal, Carey Luddy, Gary Koe, Beverly Davidson, Eliot M. Rosen & John Laterra. (2001) In vivo targeting of SF/HGF and c‐met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. The FASEB Journal 16:1, pages 1-16.
Crossref

David W. Rowe. 2002. Principles of Bone Biology. Principles of Bone Biology 1177 1193 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Reduction of Target Gene Expression by a Modified U1 snRNA

Articles from other publishers (33)

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Reduction of Target Gene Expression by a Modified U1 snRNA

Citations (33)

Articles from other publishers (33)

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date