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Molecular and Cellular Biology Volume 22, 2002 - Issue 11
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Gene Expression

The Adeno-Associated Virus Type 2 Rep Protein Regulates RNA Processing via Interaction with the Transcription Template

Jianming QiuDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri65212
&
David J. PintelDepartment of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri65212Correspondence[email protected]
Pages 3639-3652 | Received 20 Dec 2001, Accepted 04 Mar 2002, Published online: 27 Mar 2023

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Roger J. Grand. (2023) Pathogenicity and virulence of human adenovirus F41: Possible links to severe hepatitis in children. Virulence 14:1.
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Articles from other publishers (52)

Kang Ning, Cagla Aksu Kuz, Fang Cheng, Zehua Feng, Ziying Yan & Jianming Qiu. (2023) Adeno-Associated Virus Monoinfection Induces a DNA Damage Response and DNA Repair That Contributes to Viral DNA Replication. mBio 14:1.
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Liting Shao, Weiran Shen, Shengqi Wang & Jianming Qiu. (2021) Recent Advances in Molecular Biology of Human Bocavirus 1 and Its Applications. Frontiers in Microbiology 12.
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Maria Boftsi, Kinjal Majumder, Lisa R. Burger & David J. Pintel. (2020) Binding of CCCTC-Binding Factor (CTCF) to the Minute Virus of Mice Genome Is Important for Proper Processing of Viral P4-Generated Pre-mRNAs. Viruses 12:12, pages 1368.
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Xuefeng Deng, Wei Zou, Ziying Yan & Jianming Qiu. (2020) Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells. Genes 11:4, pages 439.
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Zekun Wang, Fang Cheng, John F. Engelhardt, Ziying Yan & Jianming Qiu. (2018) Development of a Novel Recombinant Adeno-Associated Virus Production System Using Human Bocavirus 1 Helper Genes. Molecular Therapy - Methods & Clinical Development 11, pages 40-51.
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Yanming Dong, Olufemi O. Fasina & David J. Pintel. (2018) The Human Bocavirus 1 NP1 Protein Is a Multifunctional Regulator of Viral RNA Processing. Journal of Virology 92:22.
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Vladimir Majerciak & Zhi-Ming Zheng. 2018. Advanced Techniques in Diagnostic Microbiology. Advanced Techniques in Diagnostic Microbiology 345 402 .
Zekun Wang, Xuefeng Deng, Wei Zou, John F. Engelhardt, Ziying Yan & Jianming Qiu. (2017) Human Bocavirus 1 Is a Novel Helper for Adeno-associated Virus Replication. Journal of Virology 91:18.
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Olufemi O. Fasina, Stephanie Stupps, Wanda Figueroa-Cuilan & David J. Pintel. (2017) Minute Virus of Canines NP1 Protein Governs the Expression of a Subset of Essential Nonstructural Proteins via Its Role in RNA Processing. Journal of Virology 91:12.
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Yaqiong Wang, Zekun Wang, Ankita Pramanik, Mario L. Santiago, Jianming Qiu & Edward B. Stephens. (2016) A chimeric human APOBEC3A protein with a three amino acid insertion confers differential HIV-1 and adeno-associated virus restriction. Virology 498, pages 149-163.
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Stefan Weger, Eva Hammer, Melanie Gonsior, Catrin Stutika & Regine Heilbronn. (2016) A Regulatory Element Near the 3′ End of the Adeno-Associated Virus rep Gene Inhibits Adenovirus Replication in cis by Means of p40 Promoter-Associated Short Transcripts . Journal of Virology 90:8, pages 3981-3993.
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Weiran Shen, Xuefeng Deng, Wei Zou, Fang Cheng, John F. Engelhardt, Ziying Yan & Jianming Qiu. (2015) Identification and Functional Analysis of Novel Nonstructural Proteins of Human Bocavirus 1. Journal of Virology 89:19, pages 10097-10109.
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Lina Wang, Zifei Yin, Yuan Wang, Yuan Lu, Daniel Zhang, Arun Srivastava, Changquan Ling, George V. Aslanidi & Chen Ling. (2015) Productive life cycle of adeno-associated virus serotype 2 in the complete absence of a conventional polyadenylation signal. Journal of General Virology 96:9, pages 2780-2787.
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Loretta Sukhu, Olufemi Fasina, Lisa Burger, Ayushi Rai, Jianming Qiu & David J. Pintel. (2013) Characterization of the Nonstructural Proteins of the Bocavirus Minute Virus of Canines. Journal of Virology 87:2, pages 1098-1104.
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Olufemi Fasina & David J. Pintel. (2013) The Adeno-Associated Virus Type 5 Small Rep Proteins Expressed via Internal Translation Initiation Are Functional. Journal of Virology 87:1, pages 296-303.
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Vladimir Majerciak & Zhi-Ming Zheng. 2013. Advanced Techniques in Diagnostic Microbiology. Advanced Techniques in Diagnostic Microbiology 693 748 .
Ana Backovic, Tiziana Cervelli, Alessandra Salvetti, Lorena Zentilin, Mauro Giacca & Alvaro Galli. (2012) Capsid protein expression and adeno-associated virus like particles assembly in Saccharomyces cerevisiae. Microbial Cell Factories 11:1.
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Qinfeng Huang, Xuefeng Deng, Sonja M. Best, Marshall E. Bloom, Yi Li & Jianming Qiu. (2012) Internal polyadenylation of parvoviral precursor mRNA limits progeny virus production. Virology 426:2, pages 167-177.
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Matthew D. Weitzman & R. Michael Linden. 2011. Adeno-Associated Virus. Adeno-Associated Virus 1 23 .
Andrew K. Cheung, Jin-Xue Long, Lv Huang & Shi-Shan Yuan. (2011) The RNA profile of porcine parvovirus 4, a boca-like virus, is unique among the parvoviruses. Archives of Virology 156:11, pages 2071-2078.
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Kimberly Schmitt, Kejun Guo, Malinda Algaier, Autumn Ruiz, Fang Cheng, Jianming Qiu, Silke Wissing, Mario L. Santiago & Edward B. Stephens. (2011) Differential virus restriction patterns of rhesus macaque and human APOBEC3A: Implications for lentivirus evolution. Virology 419:1, pages 24-42.
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Zhaojun Chen, Aaron Yun Chen, Fang Cheng & Jianming Qiu. (2010) Chipmunk Parvovirus Is Distinct from Members in the Genus Erythrovirus of the Family Parvoviridae. PLoS ONE 5:12, pages e15113.
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Fang Wang, Yongwei Wei, Chun Zhu, Xianbo Huang, Yaping Xu, Lian Yu & Xuping Yu. (2010) Novel parvovirus sublineage in the family of Parvoviridae. Virus Genes 41:2, pages 305-308.
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Armel Nicolas, Nathalie Alazard-Dany, Coline Biollay, Loredana Arata, Nelly Jolinon, Lauriane Kuhn, Myriam Ferro, Sandra K. Weller, Alberto L. Epstein, Anna Salvetti & Anna Greco. (2010) Identification of Rep-Associated Factors in Herpes Simplex Virus Type 1-Induced Adeno-Associated Virus Type 2 Replication Compartments. Journal of Virology 84:17, pages 8871-8887.
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Aaron Yun Chen, Fang Cheng, Sai Lou, Yong Luo, Zhengwen Liu, Eric Delwart, David Pintel & Jianming Qiu. (2010) Characterization of the gene expression profile of human bocavirus. Virology 403:2, pages 145-154.
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Aaron Yun Chen, Elizabeth Yan Zhang, Wuxiang Guan, Fang Cheng, Steve Kleiboeker, Thomas M. Yankee & Jianming Qiu. (2010) The small 11kDa nonstructural protein of human parvovirus B19 plays a key role in inducing apoptosis during B19 virus infection of primary erythroid progenitor cells. Blood 115:5, pages 1070-1080.
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Nathalie Dutheil, Els Henckaerts, Erik Kohlbrenner & R. Michael Linden. (2009) Transcriptional Analysis of the Adeno-Associated Virus Integration Site. Journal of Virology 83:23, pages 12512-12525.
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Zhaojun Chen, Wuxiang Guan, Fang Cheng, Aaron Yun Chen & Jianming Qiu. (2009) Molecular characterization of human parvovirus B19 genotypes 2 and 3. Virology 394:2, pages 276-285.
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Wuxiang Guan, Susan Wong, Ning Zhi & Jianming Qiu. (2009) The Genome of Human Parvovirus B19 Can Replicate in Nonpermissive Cells with the Help of Adenovirus Genes and Produces Infectious Virus. Journal of Virology 83:18, pages 9541-9553.
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Eun-Young Choi & David Pintel. (2009) Splicing of the Large Intron Present in the Nonstructural Gene of Minute Virus of Mice Is Governed by TIA-1/TIAR Binding Downstream of the Nonconsensus Donor. Journal of Virology 83:12, pages 6306-6311.
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Kevin Nash, Weijun Chen, Max Salganik & Nicholas Muzyczka. (2009) Identification of Cellular Proteins That Interact with the Adeno-Associated Virus Rep Protein. Journal of Virology 83:1, pages 454-469.
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K. David FarrisDavid J. Pintel. (2008) Improved Splicing of Adeno-Associated Viral (AAV) Capsid Protein-Supplying Pre-mRNAs Leads to Increased Recombinant AAV Vector Production. Human Gene Therapy 19:12, pages 1421-1427.
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Wuxiang Guan, Fang Cheng, Yuko Yoto, Steve Kleiboeker, Susan Wong, Ning Zhi, David J. Pintel & Jianming Qiu. (2008) Block to the Production of Full-Length B19 Virus Transcripts by Internal Polyadenylation Is Overcome by Replication of the Viral Genome. Journal of Virology 82:20, pages 9951-9963.
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Chaoyang Ye & David J. Pintel. (2008) The transcription strategy of bovine adeno-associated virus (B-AAV) combines features of both adeno-associated virus type 2 (AAV2) and type 5 (AAV5). Virology 370:2, pages 392-402.
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Ramnath Nayak & David J. Pintel. (2007) Adeno-Associated Viruses Can Induce Phosphorylation of eIF2α via PKR Activation, Which Can Be Overcome by Helper Adenovirus Type 5 Virus-Associated RNA. Journal of Virology 81:21, pages 11908-11916.
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Jianming Qiu, Fang Cheng & David Pintel. (2007) Distance-Dependent Processing of Adeno-Associated Virus Type 5 RNA Is Controlled by 5′ Exon Definition. Journal of Virology 81:15, pages 7974-7984.
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Chaoyang Ye & David J. Pintel. (2007) Upstream AP1- and CREB-Binding Sites Confer High Basal Activity on the Adeno-Associated Virus Type 5 Capsid Gene Promoter. Journal of Virology 81:6, pages 2605-2613.
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Jianming Qiu, Fang Cheng & David Pintel. (2006) Molecular characterization of caprine adeno-associated virus (AAV-Go.1) reveals striking similarity to human AAV5. Virology 356:1-2, pages 208-216.
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Chaoyang Ye, Jianming Qiu & David J. Pintel. (2006) Efficient Expression of the Adeno-Associated Virus Type 5 P41 Capsid Gene Promoter in 293 Cells Does Not Require Rep. Journal of Virology 80:13, pages 6559-6567.
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Carlos Estevez & Pedro Villegas. (2006) Recombinant Avian Adeno-Associated Virus: Transgene Expression In Vivo and Enhancement of Expression In Vitro . Avian Diseases 50:2, pages 216-221.
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Jianming Qiu, Fang Cheng & David J. Pintel. (2006) Expression Profiles of Bovine Adeno-Associated Virus and Avian Adeno-Associated Virus Display Significant Similarity to That of Adeno-Associated Virus Type 5. Journal of Virology 80:11, pages 5482-5493.
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Jianming Qiu, Fang Cheng, Lisa R. Burger & David Pintel. (2006) The Transcription Profile of Aleutian Mink Disease Virus in CRFK Cells Is Generated by Alternative Processing of Pre-mRNAs Produced from a Single Promoter. Journal of Virology 80:2, pages 654-662.
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Colin ParrishJürg Nüesch. 2005. Parvoviruses. Parvoviruses 275 289 .
Eun-Young Choi, Ann E. Newman, Lisa Burger & David Pintel. (2005) Replication of Minute Virus of Mice DNA Is Critically Dependent on Accumulated Levels of NS2. Journal of Virology 79:19, pages 12375-12381.
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Jianming Qiu, Fang Cheng, Yuko Yoto, Zoltán Zádori & David Pintel. (2005) The Expression Strategy of Goose Parvovirus Exhibits Features of both the Dependovirus and Parvovirus Genera . Journal of Virology 79:17, pages 11035-11044.
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Jianming Qiu, Laura Kakkola, Fang Cheng, Chaoyang Ye, Maria Söderlund-Venermo, Klaus Hedman & David J. Pintel. (2005) Human Circovirus TT Virus Genotype 6 Expresses Six Proteins following Transfection of a Full-Length Clone. Journal of Virology 79:10, pages 6505-6510.
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Zhengwen Liu, Jianming Qiu, Fang Cheng, Yonglie Chu, Yuko Yoto, M. Gerard O'Sullivan, Kevin E. Brown & David J. Pintel. (2004) Comparison of the Transcription Profile of Simian Parvovirus with That of the Human Erythrovirus B19 Reveals a Number of Unique Features. Journal of Virology 78:23, pages 12929-12939.
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Zhi-Ming Zheng. (2004) Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression. Journal of Biomedical Science 11:3, pages 278-294.
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Jianming Qiu & David J. Pintel. (2004) Alternative Polyadenylation of Adeno-associated Virus Type 5 RNA within an Internal Intron Is Governed by the Distance between the Promoter and the Intron and Is Inhibited by U1 Small Nuclear RNP Binding to the Intervening Donor. Journal of Biological Chemistry 279:15, pages 14889-14898.
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G Fédière, M El-Far, Y Li, M Bergoin & P Tijssen. (2004) Expression strategy of densonucleosis virus from Mythimna loreyi. Virology 320:1, pages 181-189.
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Jianming Qiu, Ramnath Nayak & David J. Pintel. (2004) Alternative Polyadenylation of Adeno-Associated Virus Type 5 RNA within an Internal Intron Is Governed by both a Downstream Element within the Intron 3′ Splice Acceptor and an Element Upstream of the P41 Initiation Site. Journal of Virology 78:1, pages 83-93.
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Jianming Qiu, Ramnath Nayak, Gregory E. Tullis & David J. Pintel. (2002) Characterization of the Transcription Profile of Adeno-Associated Virus Type 5 Reveals a Number of Unique Features Compared to Previously Characterized Adeno-Associated Viruses. Journal of Virology 76:24, pages 12435-12447.
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