Molecular and Cellular Biology, Volume 22, Issue 11 (2002)

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Molecular and Cellular Biology, Volume 22, Issue 11 (2002)

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Article
How Selenium Has Altered Our Understanding of the Genetic Code
Dolph L. Hatfield & Vadim N. Gladyshev
Pages: 3565-3576
Published online: 27 Mar 2023
First Page PreviewforHow Selenium Has Altered Our Understanding of the Genetic Code | Full Text | References | PDF (459.2 KB)
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Cell Growth and Development

Article
Identification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis
Michela Marani, Tencho Tenev, David Hancock, Julian Downward & Nicholas R. Lemoine
Pages: 3577-3589
Published online: 27 Mar 2023
AbstractforIdentification of Novel Isoforms of the BH3 Domain Protein Bim Which Directly Activate Bax To Trigger Apoptosis | Full Text | References | PDF (646.5 KB)
  • 43 Views
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Article
Antagonistic Interactions between Yeast [PSI+] and [URE3] Prions and Curing of [URE3] by Hsp70 Protein Chaperone Ssa1p but Not by Ssa2p
Christine Schwimmer & Daniel C. Masison
Pages: 3590-3598
Published online: 27 Mar 2023
AbstractforAntagonistic Interactions between Yeast [PSI+] and [URE3] Prions and Curing of [URE3] by Hsp70 Protein Chaperone Ssa1p but Not by Ssa2p | Full Text | References | PDF (385.6 KB)
  • 18 Views
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Article
APS Facilitates c-Cbl Tyrosine Phosphorylation and GLUT4 Translocation in Response to Insulin in 3T3-L1 Adipocytes
Jun Liu, Akiko Kimura, Christian A. Baumann & Alan R. Saltiel
Pages: 3599-3609
Published online: 27 Mar 2023
AbstractforAPS Facilitates c-Cbl Tyrosine Phosphorylation and GLUT4 Translocation in Response to Insulin in 3T3-L1 Adipocytes | Full Text | References | PDF (627 KB)
  • 44 Views
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Article
mtCLIC/CLIC4, an Organellular Chloride Channel Protein, Is Increased by DNA Damage and Participates in the Apoptotic Response to p53
Ester Fernández-Salas, Kwang S. Suh, Vladislav V. Speransky, Wendy L. Bowers, Joshua M. Levy, Tracey Adams, Kamal R. Pathak, Lindsay E. Edwards, Daniel D. Hayes, Christina Cheng, Alasdair C. Steven, Wendy C. Weinberg & Stuart H. Yuspa
Pages: 3610-3620
Published online: 27 Mar 2023
AbstractformtCLIC/CLIC4, an Organellular Chloride Channel Protein, Is Increased by DNA Damage and Participates in the Apoptotic Response to p53 | Full Text | References | PDF (624.5 KB)
  • 40 Views
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Article
B56-Associated Protein Phosphatase 2A Is Required For Survival and Protects from Apoptosis in Drosophila melanogaster
Xinghai Li, Anne Scuderi, Anthea Letsou & David M. Virshup
Pages: 3674-3684
Published online: 27 Mar 2023
AbstractforB56-Associated Protein Phosphatase 2A Is Required For Survival and Protects from Apoptosis in Drosophila melanogaster | Full Text | References | PDF (530 KB)
  • 15 Views
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Article
ACK Family Tyrosine Kinase Activity Is a Component of Dcdc42 Signaling during Dorsal Closure in Drosophila melanogaster
Kai Ping Sem, Baharak Zahedi, Ivan Tan, Maria Deak, Louis Lim & Nicholas Harden
Pages: 3685-3697
Published online: 27 Mar 2023
AbstractforACK Family Tyrosine Kinase Activity Is a Component of Dcdc42 Signaling during Dorsal Closure in Drosophila melanogaster | Full Text | References | PDF (752.6 KB)
  • 14 Views
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Article
Cyclic AMP Blocks Cell Growth through Raf-1-Dependent and Raf-1-Independent Mechanisms
Nicolas Dumaz, Yvonne Light & Richard Marais
Pages: 3717-3728
Published online: 27 Mar 2023
AbstractforCyclic AMP Blocks Cell Growth through Raf-1-Dependent and Raf-1-Independent Mechanisms | Full Text | References | PDF (440.1 KB)
  • 9 Views
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Article
Induced Expression and Association of the Mona/Gads Adapter and Gab3 Scaffolding Protein during Monocyte/Macrophage Differentiation
Caroline Bourgin, Roland P. Bourette, Sylvie Arnaud, Yan Liu, Larry R. Rohrschneider & Guy Mouchiroud
Pages: 3744-3756
Published online: 27 Mar 2023
AbstractforInduced Expression and Association of the Mona/Gads Adapter and Gab3 Scaffolding Protein during Monocyte/Macrophage Differentiation | Full Text | References | PDF (671.2 KB)
  • 15 Views
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Article
Paip1 Interacts with Poly(A) Binding Protein through Two Independent Binding Motifs
Guylaine Roy, Gregory De Crescenzo, Kianoush Khaleghpour, Avak Kahvejian, Maureen O'Connor-McCourt & Nahum Sonenberg
Pages: 3769-3782
Published online: 27 Mar 2023
AbstractforPaip1 Interacts with Poly(A) Binding Protein through Two Independent Binding Motifs | Full Text | References | PDF (882 KB)
  • 68 Views
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Article
Desumoylation Activity of Axam, a Novel Axin-Binding Protein, Is Involved in Downregulation of β-Catenin
Takayuki Kadoya, Hideki Yamamoto, Toshiaki Suzuki, Akira Yukita, Akimasa Fukui, Tatsuo Michiue, Toshimasa Asahara, Keiji Tanaka, Makoto Asashima & Akira Kikuchi
Pages: 3803-3819
Published online: 27 Mar 2023
AbstractforDesumoylation Activity of Axam, a Novel Axin-Binding Protein, Is Involved in Downregulation of β-Catenin | Full Text | References | PDF (1.8 MB)
  • 9 Views
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Article
Essential Role of AKT-1/Protein Kinase Bα in PTEN-Controlled Tumorigenesis
Bangyan Stiles, Valeriya Gilman, Natalya Khanzenzon, Ralf Lesche, Annie Li, Rong Qiao, Xin Liu & Hong Wu
Pages: 3842-3851
Published online: 27 Mar 2023
AbstractforEssential Role of AKT-1/Protein Kinase Bα in PTEN-Controlled Tumorigenesis | Full Text | References | PDF (727.4 KB)
  • 19 Views
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Article
The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas
Peichuan Zhang, Barbara McGrath, Sheng'ai Li, Ami Frank, Frank Zambito, Jamie Reinert, Maureen Gannon, Kun Ma, Kelly McNaughton & Douglas R. Cavener
Pages: 3864-3874
Published online: 27 Mar 2023
AbstractforThe PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas | Full Text | References | PDF (1.1 MB)
  • 133 Views
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Article
Role of SHP-2 in Fibroblast Growth Factor Receptor-Mediated Suppression of Myogenesis in C2C12 Myoblasts
Maria I. Kontaridis, Xiangdong Liu, Lei Zhang & Anton M. Bennett
Pages: 3875-3891
Published online: 27 Mar 2023
AbstractforRole of SHP-2 in Fibroblast Growth Factor Receptor-Mediated Suppression of Myogenesis in C2C12 Myoblasts | Full Text | References | PDF (997.7 KB)
  • 33 Views
  • 38 CrossRef citations
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Article
Phosphorylation of NFATc4 by p38 Mitogen-Activated Protein Kinases
Teddy T. C. Yang, Qiufang Xiong, Hervé Enslen, Roger J. Davis & Chi-Wing Chow
Pages: 3892-3904
Published online: 27 Mar 2023
AbstractforPhosphorylation of NFATc4 by p38 Mitogen-Activated Protein Kinases | Full Text | References | PDF (711.3 KB)
  • 23 Views
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Article
Intracellular Retention of Glycosylphosphatidyl Inositol-Linked Proteins in Caveolin-Deficient Cells
Federica Sotgia, Babak Razani, Gloria Bonuccelli, William Schubert, Michela Battista, Hyangkyu Lee, Franco Capozza, Ann Lane Schubert, Carlo Minetti, J. Thomas Buckley & Michael P. Lisanti
Pages: 3905-3926
Published online: 27 Mar 2023
AbstractforIntracellular Retention of Glycosylphosphatidyl Inositol-Linked Proteins in Caveolin-Deficient Cells | Full Text | References | PDF (953.3 KB)
  • 34 Views
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Article
Characterization of a High-Molecular-Weight Notch Complex in the Nucleus of Notchic-Transformed RKE Cells and in a Human T-Cell Leukemia Cell Line
Shawn Jeffries, David J. Robbins & Anthony J. Capobianco
Pages: 3927-3941
Published online: 27 Mar 2023
AbstractforCharacterization of a High-Molecular-Weight Notch Complex in the Nucleus of Notchic-Transformed RKE Cells and in a Human T-Cell Leukemia Cell Line | Full Text | References | PDF (692.2 KB)
  • 10 Views
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Article
A Novel Interferon Regulatory Factor (IRF), IRF-10, Has a Unique Role in Immune Defense and Is Induced by the v-Rel Oncoprotein
Jiří Nehyba, Radmila Hrdličková, Joan Burnside & Henry R. Bose Jr.
Pages: 3942-3957
Published online: 27 Mar 2023
AbstractforA Novel Interferon Regulatory Factor (IRF), IRF-10, Has a Unique Role in Immune Defense and Is Induced by the v-Rel Oncoprotein | Full Text | References | PDF (643 KB)
  • 27 Views
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Transcriptional Regulation

Article
Synergy among Nuclear Receptor Coactivators: Selective Requirement for Protein Methyltransferase and Acetyltransferase Activities
Young-Ho Lee, Stephen S. Koh, Xing Zhang, Xiaodong Cheng & Michael R. Stallcup
Pages: 3621-3632
Published online: 27 Mar 2023
AbstractforSynergy among Nuclear Receptor Coactivators: Selective Requirement for Protein Methyltransferase and Acetyltransferase Activities | Full Text | References | PDF (249.9 KB)
  • 30 Views
  • 141 CrossRef citations
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Article
Nucleosome Remodeling by the Human SWI/SNF Complex Requires Transient Global Disruption of Histone-DNA Interactions
Sayura Aoyagi, Geeta Narlikar, Chunyang Zheng, Saiïd Sif, Robert E. Kingston & Jeffrey J. Hayes
Pages: 3653-3662
Published online: 27 Mar 2023
AbstractforNucleosome Remodeling by the Human SWI/SNF Complex Requires Transient Global Disruption of Histone-DNA Interactions | Full Text | References | PDF (372.7 KB)
  • 67 Views
  • 39 CrossRef citations
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Article
The Transcription Factor B-Myb Is Maintained in an Inhibited State in Target Cells through Its Interaction with the Nuclear Corepressors N-CoR and SMRT
Xiaolin Li & Donald P. McDonnell
Pages: 3663-3673
Published online: 27 Mar 2023
AbstractforThe Transcription Factor B-Myb Is Maintained in an Inhibited State in Target Cells through Its Interaction with the Nuclear Corepressors N-CoR and SMRT | Full Text | References | PDF (318.4 KB)
  • 12 Views
  • 29 CrossRef citations
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Article
Ligand-Selective Potentiation of Rat Mineralocorticoid Receptor Activation Function 1 by a CBP-Containing Histone Acetyltransferase Complex
Hirochika Kitagawa, Junn Yanagisawa, Hiroaki Fuse, Satoko Ogawa, Yoshiko Yogiashi, Atsuro Okuno, Hiromichi Nagasawa, Toshihiro Nakajima, Toshio Matsumoto & Shigeaki Kato
Pages: 3698-3706
Published online: 27 Mar 2023
AbstractforLigand-Selective Potentiation of Rat Mineralocorticoid Receptor Activation Function 1 by a CBP-Containing Histone Acetyltransferase Complex | Full Text | References | PDF (579.5 KB)
  • 12 Views
  • 82 CrossRef citations
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Article
Inhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1
Wei Hong, Alexander Y. Kim, Sokun Ky, Carrie Rakowski, Sang-Beom Seo, Debabrata Chakravarti, Michael Atchison & Gerd A. Blobel
Pages: 3729-3743
Published online: 27 Mar 2023
AbstractforInhibition of CBP-Mediated Protein Acetylation by the Ets Family Oncoprotein PU.1 | Full Text | References | PDF (594.8 KB)
  • 15 Views
  • 54 CrossRef citations
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Article
CK2 Forms a Stable Complex with TFIIIB and Activates RNA Polymerase III Transcription in Human Cells
Imogen M. Johnston, Simon J. Allison, Jennifer P. Morton, Laura Schramm, Pamela H. Scott & Robert J. White
Pages: 3757-3768
Published online: 27 Mar 2023
AbstractforCK2 Forms a Stable Complex with TFIIIB and Activates RNA Polymerase III Transcription in Human Cells | Full Text | References | PDF (405.8 KB)
  • 11 Views
  • 58 CrossRef citations
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Article
Critical Role of Diacylglycerol- and Phospholipid-Regulated Protein Kinase Cε in Induction of Low-Density Lipoprotein Receptor Transcription in Response to Depletion of Cholesterol
Kamal D. Mehta, Anna Radominska-Pandya, Gurpreet S. Kapoor, Bhuvanesh Dave & Brett A. Atkins
Pages: 3783-3793
Published online: 27 Mar 2023
AbstractforCritical Role of Diacylglycerol- and Phospholipid-Regulated Protein Kinase Cε in Induction of Low-Density Lipoprotein Receptor Transcription in Response to Depletion of Cholesterol | Full Text | References | PDF (275.9 KB)
  • 6 Views
  • 26 CrossRef citations
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Article
Conserved CTCF Insulator Elements Flank the Mouse and Human β-Globin Loci
Catherine M. Farrell, Adam G. West & Gary Felsenfeld
Pages: 3820-3831
Published online: 27 Mar 2023
AbstractforConserved CTCF Insulator Elements Flank the Mouse and Human β-Globin Loci | Full Text | References | PDF (639.3 KB)
  • 36 Views
  • 131 CrossRef citations
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Article
The Acetyltransferase Activity of CBP Is Required for wingless Activation and H4 Acetylation in Drosophila melanogaster
William H. Ludlam, Matthew H. Taylor, Kirk G. Tanner, John M. Denu, Richard H. Goodman & Sarah M. Smolik
Pages: 3832-3841
Published online: 27 Mar 2023
AbstractforThe Acetyltransferase Activity of CBP Is Required for wingless Activation and H4 Acetylation in Drosophila melanogaster | Full Text | References | PDF (1.1 MB)
  • 35 Views
  • 34 CrossRef citations
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Article
Strand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity
Li Liu, Michael C. Rice, Miya Drury, Shuqiu Cheng, Howard Gamper & Eric B. Kmiec
Pages: 3852-3863
Published online: 27 Mar 2023
AbstractforStrand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity | Full Text | References | PDF (970.3 KB)
  • 6 Views
  • 62 CrossRef citations
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Neutral Sphingomyelinase 1 Deficiency in the Mouse Causes No Lipid Storage Disease
Markus Zumbansen & Wilhelm Stoffel
Pages: 3633-3638
Published online: 27 Mar 2023
AbstractforNeutral Sphingomyelinase 1 Deficiency in the Mouse Causes No Lipid Storage Disease | Full Text | References | PDF (273.6 KB)
  • 11 Views
  • 52 CrossRef citations
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Article
Growth and Early Postimplantation Defects in Mice Deficient for the Bromodomain-Containing Protein Brd4
Denis Houzelstein, Simon L. Bullock, Denise E. Lynch, Elena F. Grigorieva, Valerie A. Wilson & Rosa S. P. Beddington
Pages: 3794-3802
Published online: 27 Mar 2023
AbstractforGrowth and Early Postimplantation Defects in Mice Deficient for the Bromodomain-Containing Protein Brd4 | Full Text | References | PDF (761.2 KB)
  • 96 Views
  • 225 CrossRef citations
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Gene Expression

Article
The Adeno-Associated Virus Type 2 Rep Protein Regulates RNA Processing via Interaction with the Transcription Template
Jianming Qiu & David J. Pintel
Pages: 3639-3652
Published online: 27 Mar 2023
AbstractforThe Adeno-Associated Virus Type 2 Rep Protein Regulates RNA Processing via Interaction with the Transcription Template | Full Text | References | PDF (629.6 KB)
  • 67 Views
  • 53 CrossRef citations
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Cell and Organelle Structure and Assembly

Article
tRNAs in Trypanosoma brucei: Genomic Organization, Expression, and Mitochondrial Import
Timothy H. P. Tan, Roland Pach, Anne Crausaz, Al Ivens & André Schneider
Pages: 3707-3716
Published online: 27 Mar 2023
AbstractfortRNAs in Trypanosoma brucei: Genomic Organization, Expression, and Mitochondrial Import | Full Text | References | PDF (476.7 KB)
  • 42 Views
  • 80 CrossRef citations
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