Advanced search
Publication Cover
Molecular and Cellular Biology Volume 23, 2003 - Issue 1
Submit an article Journal homepage
59
Views
112
CrossRef citations to date
0
Altmetric
Transcriptional Regulation

LXXLL-Related Motifs in Dax-1 Have Target Specificity for the Orphan Nuclear Receptors Ad4BP/SF-1 and LRH-1

Taiga Suzuki1 Department of Developmental Biology, National Institute for Basic Biology, Okazaki444-8585;2 Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto606-8507
,
Megumi Kasahara3 Department of Natural Sciences, Hyogo University of Teacher Education, Hyogo673-1494
,
Hidefumi Yoshioka3 Department of Natural Sciences, Hyogo University of Teacher Education, Hyogo673-1494
,
Ken-ichirou Morohashi1 Department of Developmental Biology, National Institute for Basic Biology, Okazaki444-8585;4 Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Corporation, Kawaguchi332-0012Correspondence[email protected]
&
Kazuhiko Umesono2 Institute for Virus Research, Kyoto University, Sakyo-ku, Kyoto606-8507;5 Graduate School for Biostudies, Kyoto University, Sakyo-ku, Kyoto606-8502, Japan
Pages 238-249 | Received 05 Apr 2002, Accepted 24 Sep 2002, Published online: 27 Mar 2023

Citations (112)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (8)

Christina Nadolny & Xiaoqun Dong. (2015) Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancer. Cancer Biology & Therapy 16:7, pages 997-1004.
Read now
Kousuke Uranishi, Tadayuki Akagi, Chuanhai Sun, Hiroshi Koide & Takashi Yokota. (2013) Dax1 Associates with Esrrb and Regulates Its Function in Embryonic Stem Cells. Molecular and Cellular Biology 33:10, pages 2056-2066.
Read now
Natasha C. Lucki, Donghui Li, Sibali Bandyopadhyay, Elaine Wang, Alfred H. Merrill & Marion B. Sewer. (2012) Acid Ceramidase (ASAH1) Represses Steroidogenic Factor 1-Dependent Gene Transcription in H295R Human Adrenocortical Cells by Binding to the Receptor. Molecular and Cellular Biology 32:21, pages 4419-4431.
Read now
Enzo Lalli & Javier Alonso. (2010) Targeting DAX-1 in embryonic stem cells and cancer. Expert Opinion on Therapeutic Targets 14:2, pages 169-177.
Read now
Chuanhai Sun, Yuhki Nakatake, Tadayuki Akagi, Hiroki Ura, Takahiko Matsuda, Akira Nishiyama, Hiroshi Koide, Minoru S. H. Ko, Hitoshi Niwa & Takashi Yokota. (2009) Dax1 Binds to Oct3/4 and Inhibits Its Transcriptional Activity in Embryonic Stem Cells. Molecular and Cellular Biology 29:16, pages 4574-4583.
Read now
Bin Xu, Wei-Hsiung Yang, Isabelle Gerin, Chang-Deng Hu, Gary D. Hammer & Ronald J. Koenig. (2009) Dax-1 and Steroid Receptor RNA Activator (SRA) Function as Transcriptional Coactivators for Steroidogenic Factor 1 in Steroidogenesis. Molecular and Cellular Biology 29:7, pages 1719-1734.
Read now
Mohamad Zubair, Keith L. Parker & Ken-ichirou Morohashi. (2008) Developmental Links between the Fetal and Adult Zones of the Adrenal Cortex Revealed by Lineage Tracing. Molecular and Cellular Biology 28:23, pages 7030-7040.
Read now
Liu Yi-Wen. (2007) Interrenal Organogenesis in the Zebrafish Model. Organogenesis 3:1, pages 44-48.
Read now

Articles from other publishers (104)

Maki Gau, Ryota Suga, Atsushi Hijikata, Ayako Kashimada, Masatoshi Takagi, Ryuichi Nakagawa, Kei Takasawa, Tsuyoshi Shirai, Kenichi Kashimada & Tomohiro Morio. (2023) A novel variant of NR5A1, p.R350W implicates potential interactions with unknown co-factors or ligands. Frontiers in Endocrinology 13.
Crossref
Tetsuya Mizutani, Makoto Orisaka, Shinya Kawabe, Ririko Morichika, Miki Uesaka & Yoshio Yoshida. (2023) YAP/TAZ-TEAD is a novel transcriptional regulator of genes encoding steroidogenic enzymes in rat granulosa cells and KGN cells. Molecular and Cellular Endocrinology 559, pages 111808.
Crossref
Wei Zhang, Yan Li, Sijie Chen, Cuizhen Zhang, Lili Chen & Gang Peng. (2022) nr0b1 (DAX1) loss of function in zebrafish causes hypothalamic defects via abnormal progenitor proliferation and differentiation. Journal of Genetics and Genomics 49:3, pages 217-229.
Crossref
Nikita Sandhu, Satyavati Rana & Kiran Meena. (2021) Nuclear receptor subfamily 5 group A member 2 (NR5A2): role in health and diseases. Molecular Biology Reports 48:12, pages 8155-8170.
Crossref
Hongjuan Shi, Xiaoying Ru, Umar Farouk Mustapha, Dongneng Jiang, Yang Huang, Shuhui Pan, Chunhua Zhu & Guangli Li. (2021) Characterization, expression, and regulatory effects of nr0b1a and nr0b1b in spotted scat (Scatophagus argus). Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 256, pages 110644.
Crossref
Da-Bei Fan, Li Li & Hao-Hao Zhang. (2021) Nonsense variant of NR0B1 causes hormone disorders associated with congenital adrenal hyperplasia. Scientific Reports 11:1.
Crossref
Suchit Gupta, Kriti Joshi, Ghazala Zaidi, Aditya Narayan Sarangi, Kausik Mandal, Nisha Bhavani, Praveen V. Pavithran, Mini G. Pillai, Surya K. Singh, Tushar Godbole, Vijayalakshmi Bhatia & Eesh Bhatia. (2019) Novel mutations and spectrum of the disease of NR0B1 (DAX1) -related adrenal insufficiency in Indian children . Journal of Pediatric Endocrinology and Metabolism 32:8, pages 863-869.
Crossref
Haihong Qian, Ping He, Fenglin Lv & Wei Wu. (2019) Genome-wide analysis of LXXLL-mediated DAX1/SHP–nuclear receptor interaction network and rational design of stapled LXXLL-based peptides to target the specific network profile. International Journal of Biological Macromolecules 129, pages 13-22.
Crossref
Marie-Charlotte Meinsohn, Olivia E. Smith, Kalyne Bertolin & Bruce D. Murphy. (2019) The Orphan Nuclear Receptors Steroidogenic Factor-1 and Liver Receptor Homolog-1: Structure, Regulation, and Essential Roles in Mammalian Reproduction. Physiological Reviews 99:2, pages 1249-1279.
Crossref
Xiaohua Xia, Weiran Huo, Ruyan Wan, Peijin Wang & Zhongjie Chang. (2018) Cloning, characterization and function analysis of DAX1 in Chinese loach (Paramisgurnus dabryanus). Genetica 146:6, pages 487-496.
Crossref
Rafah Mackeh, Alexandra K. Marr, Abeer Fadda & Tomoshige Kino. (2018) C2H2-Type Zinc Finger Proteins: Evolutionarily Old and New Partners of the Nuclear Hormone Receptors. Nuclear Receptor Signaling 15, pages 155076291880107.
Crossref
Yong-fang Jia, Xiao-hua Xia, Wan-wan Zhang, Xiao-lin Ji, Jian-jun Chen, Li Li, Nan Ping, Qi-yan Du & Zhong-jie Chang. (2017) Characterization and expression of dax1 during embryonic and gonad development in the carp (Cyprinus carpio). Turkish Journal of Biochemistry 42:2.
Crossref
Sijie Chen, Hefei Zhang, Fenghua Wang, Wei Zhang & Gang Peng. (2016) nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation. Molecular and Cellular Endocrinology 433, pages 105-116.
Crossref
Leslie Pick. (2015) Hox genes, evo-devo, and the case of the ftz gene. Chromosoma 125:3, pages 535-551.
Crossref
TINGTING YU, JIAN WANG, YONGGUO YU, XIAODONG HUANG, QIHUA FU, YIPING SHEN & FUXIANG CHEN. (2016) X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism: Identification and in vitro study of a novel small indel in the NR0B1 gene. Molecular Medicine Reports 13:5, pages 4039-4045.
Crossref
Xiaoyong Zhi, X. Edward Zhou, Karsten Melcher & H. Eric Xu. (2016) Structures and regulation of non-X orphan nuclear receptors: A retinoid hypothesis. The Journal of Steroid Biochemistry and Molecular Biology 157, pages 27-40.
Crossref
Shailaja D. Divekar, Deanna M. Tiek, Aileen Fernandez & Rebecca B. Riggins. (2016) Estrogen-related Receptor β (ERRβ) – Renaissance Receptor or Receptor Renaissance?. Nuclear Receptor Signaling 14:1, pages nrs.14002.
Crossref
Aleksandra Rojek, Maciej R. Krawczynski, Aleksander Jamsheer, Anna Sowinska-Seidler, Barbara Iwaniszewska, Ewa Malunowicz & Marek Niedziela. (2016) X-Linked Adrenal Hypoplasia Congenita in a Boy due to a Novel Deletion of the Entire NR0B1 (DAX1) and MAGEB1 – 4 Genes . International Journal of Endocrinology 2016, pages 1-7.
Crossref
Elena P. Sablin, Raymond D. Blind, Rubatharshini Uthayaruban, Hsiu-Ju Chiu, Ashley M. Deacon, Debanu Das, Holly A. Ingraham & Robert J. Fletterick. (2015) Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket. Journal of Structural Biology 192:3, pages 342-348.
Crossref
Qing Hu, Wei Guo, Yu Gao, Rong Tang & Dapeng Li. (2015) Molecular cloning and characterization of amh and dax1 genes and their expression during sex inversion in rice-field eel Monopterus albus. Scientific Reports 5:1.
Crossref
Sokrates Stein & Kristina Schoonjans. (2015) Molecular basis for the regulation of the nuclear receptor LRH-1. Current Opinion in Cell Biology 33, pages 26-34.
Crossref
Setsuko Fujii, Satomi Nishikawa-Torikai, Yoko Futatsugi, Yayoi Toyooka, Mariko Yamane, Satoshi Ohtsuka & Hitoshi Niwa. (2015) Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells. Scientific Reports 5:1.
Crossref
Pauline Roumaud & Luc J. Martin. (2015) Roles of leptin, adiponectin and resistin in the transcriptional regulation of steroidogenic genes contributing to decreased Leydig cells function in obesity. Hormone Molecular Biology and Clinical Investigation 24:1.
Crossref
Tetsuya Mizutani, Shin Ishikane, Shinya Kawabe, Akihiro Umezawa & Kaoru Miyamoto. (2015) Transcriptional regulation of genes related to progesterone production [Review]. Endocrine Journal 62:9, pages 757-763.
Crossref
Núria Camats, Laura Audí, Mónica Fernández-Cancio, Pilar Andaluz, Primus E. Mullis, Antonio Carrascosa & Christa E. Flück. (2015) LRH-1 May Rescue SF-1 Deficiency for Steroidogenesis: An in vitro<b> </b>and in vivo<b> </b>Study. Sexual Development 9:3, pages 144-154.
Crossref
A. S. Orekhova & P. M. Rubtsov. (2015) DAX1, an unusual member of the nuclear receptor superfamily with diverse functions. Molecular Biology 49:1, pages 65-76.
Crossref
Robert Stickels, Kevin Clark, Thomas N. Heider, Deidre M. Mattiske, Marilyn B. Renfree & Andrew J. Pask. (2015) DAX1/NR0B1 Was Expressed During Mammalian Gonadal Development and Gametogenesis Before It Was Recruited to the Eutherian X Chromosome1. Biology of Reproduction 92:1.
Crossref
Michael A. Hale, Galvin H. Swift, Chinh Q. Hoang, Tye G. Deering, Toshi Masui, Youn-Kyoung Lee, Jumin Xue & Raymond J. MacDonald. (2014) The nuclear hormone receptor family member NR5A2 controls aspects of multipotent progenitor cell formation and acinar differentiation during pancreatic organogenesis. Development 141:16, pages 3123-3133.
Crossref
Hailong Li, Jianguo Liu, Xiaoting Huang, Dan Wang & Zhifeng Zhang. (2014) Characterization, expression and function analysis of DAX1 gene of scallop (Chlamys farreri jones and preston 1904) during its gametogenesis. Journal of Ocean University of China 13:4, pages 696-704.
Crossref
Enzo Lalli. (2014) Role of Orphan Nuclear Receptor DAX-1/NR0B1 in Development, Physiology, and Disease. Advances in Biology 2014, pages 1-19.
Crossref
Takashi Yazawa. (2014) Differentiation of mesenchymal stem cells into gonad and adrenal steroidogenic cells. World Journal of Stem Cells 6:2, pages 203.
Crossref
Kevin C. Knower, Ashwini L. Chand, Natalie Eriksson, Kiyoshi Takagi, Yasuhiro Miki, Hironobu Sasano, Jane E. Visvader, Geoffrey J. Lindeman, John W. Funder, Peter J. Fuller, Evan R. Simpson, Wayne D. Tilley, Peter J. Leedman, J. Dinny Graham, George E. O. Muscat, Christine L. Clarke & Colin D. Clyne. (2013) Distinct nuclear receptor expression in stroma adjacent to breast tumors. Breast Cancer Research and Treatment 142:1, pages 211-223.
Crossref
Seung Won Ahn, Gil-Tae Gang, Yong Deuk Kim, Ryun-Sup Ahn, Robert A. Harris, Chul-Ho Lee & Hueng-Sik Choi. (2013) Insulin Directly Regulates Steroidogenesis via Induction of the Orphan Nuclear Receptor DAX-1 in Testicular Leydig Cells. Journal of Biological Chemistry 288:22, pages 15937-15946.
Crossref
Meng Li, Lihong Wang, Houpeng Wang, Hongwei Liang, Yao Zheng, Fang Qin, Shaozhen Liu, Yingying Zhang & Zaizhao Wang. (2013) Molecular cloning and characterization of amh, dax1 and cyp19a1a genes and their response to 17α-methyltestosterone in Pengze crucian carp. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 157:4, pages 372-381.
Crossref
Salwan Maqdasy, Marine Baptissart, Aurélie Vega, Silvère Baron, Jean-Marc A. Lobaccaro & David H. Volle. (2013) Cholesterol and male fertility: What about orphans and adopted?. Molecular and Cellular Endocrinology 368:1-2, pages 30-46.
Crossref
Qin Wang & Austin J. Cooney. 2013. Transcriptional and Translational Regulation of Stem Cells. Transcriptional and Translational Regulation of Stem Cells 287 306 .
Halagowder Devaraj, Marimuthu Saravanakumar & Mani Thiyagu. (2012) Induction of Ovarian Maturation in Penaeus monodon by Molecular Signal Interventional Approach . Journal of Experimental Zoology Part B: Molecular and Developmental Evolution 318:7, pages 572-585.
Crossref
Kyren A. Lazarus, Dhilushi Wijayakumara, Ashwini L. Chand, Evan R. Simpson & Colin D. Clyne. (2012) Therapeutic potential of Liver Receptor Homolog-1 modulators. The Journal of Steroid Biochemistry and Molecular Biology 130:3-5, pages 138-146.
Crossref
Anna Ehrlund & Eckardt Treuter. (2012) Ligand-independent actions of the orphan receptors/corepressors DAX-1 and SHP in metabolism, reproduction and disease. The Journal of Steroid Biochemistry and Molecular Biology 130:3-5, pages 169-179.
Crossref
Yoshifumi Yajima, Mun'delanji C. Vestergaard & Masahiro Takagi. (2012) Damage in brain development by morpholino knockdown of zebrafish dax1. Journal of Bioscience and Bioengineering 113:6, pages 683-688.
Crossref
Louisa M. Ludbrook, Pascal Bernard, Stefan Bagheri-Fam, Janelle Ryan, Ryohei Sekido, Dagmar Wilhelm, Robin Lovell-Badge & Vincent R. Harley. (2012) Excess DAX1 Leads to XY Ovotesticular Disorder of Sex Development (DSD) in Mice by Inhibiting Steroidogenic Factor-1 (SF1) Activation of the Testis Enhancer of SRY-box-9 (Sox9). Endocrinology 153:4, pages 1948-1958.
Crossref
Ji-Hye Yun, Chul-Jin Lee, Jin-Won Jung & Weon-Tae Lee. (2012) Solution Structure of LXXLL-related Cofactor Peptide of Orphan Nuclear Receptor FTZ-F1. Bulletin of the Korean Chemical Society 33:2, pages 583-588.
Crossref
Fumiaki Yumoto, Phuong Nguyen, Elena P. Sablin, John D. Baxter, Paul Webb & Robert J. Fletterick. (2011) Structural basis of coactivation of liver receptor homolog-1 by β-catenin. Proceedings of the National Academy of Sciences 109:1, pages 143-148.
Crossref
Megumi Tsuchiya, Hidesato Ogawa, Taiga Suzuki, Noriyuki Sugiyama, Tokuko Haraguchi & Yasushi Hiraoka. (2011) Exportin 4 Interacts with Sox9 through the HMG Box and Inhibits the DNA Binding of Sox9. PLoS ONE 6:10, pages e25694.
Crossref
Unmesh Jadhav, Rebecca M. Harris & J. Larry Jameson. (2011) Hypogonadotropic hypogonadism in subjects with DAX1 mutations. Molecular and Cellular Endocrinology 346:1-2, pages 65-73.
Crossref
Joshua O. Scheys, Joanne H. Heaton & Gary D. Hammer. (2011) Evidence of Adrenal Failure in Aging Dax1-Deficient Mice. Endocrinology 152:9, pages 3430-3439.
Crossref
A. S. Orekhova, P. S. Sverdlova, P. V. Spirin, O. G. Leonova, V. I. Popenko, V. S. Prassolov & P. M. Rubtsov. (2011) A new bidirectional promoter from the human genome. Molecular Biology 45:3, pages 442-450.
Crossref
Jayne Sierens, Irumini Jakody, Yogavalli Poobalan, Sarah J. Meachem, Kevin Knower, Morag J. Young, Rosa Sirianni, Vincenzo Pezzi & Colin D. Clyne. (2010) Localization and regulation of aromatase liver receptor homologue-1 in the developing rat testis. Molecular and Cellular Endocrinology 323:2, pages 307-313.
Crossref
Erling A. Hoivik, Aurélia E. Lewis, Linda Aumo & Marit Bakke. (2010) Molecular aspects of steroidogenic factor 1 (SF-1). Molecular and Cellular Endocrinology 315:1-2, pages 27-39.
Crossref
Michelle Kinsey, Richard Smith, Anita K. Iyer, Edward R.B. McCabe & Stephen L. Lessnick. (2009) EWS/FLI and Its Downstream Target NR0B1 Interact Directly to Modulate Transcription and Oncogenesis in Ewing's Sarcoma. Cancer Research 69:23, pages 9047-9055.
Crossref
Hidesato Ogawa, Tomoko KomatsuYasushi Hiraoka & Ken-ichirou Morohashi. (2009) Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated Nuclear Receptor Ad4BP/SF-1. Molecular Biology of the Cell 20:19, pages 4235-4245.
Crossref
Balachandar Nedumaran, Sungpyo Hong, Yuan-Bin Xie, Yong-Hoon Kim, Woo-Young Seo, Min-Woo Lee, Chul Ho Lee, Seung-Hoi Koo & Hueng-Sik Choi. (2009) DAX-1 Acts as a Novel Corepressor of Orphan Nuclear Receptor HNF4α and Negatively Regulates Gluconeogenic Enzyme Gene Expression. Journal of Biological Chemistry 284:40, pages 27511-27523.
Crossref
Gerd Wohlfahrt, Julius Sipilä & Lars-Olof Pietilä. (2009) Field-based comparison of ligand and coactivator binding sites of nuclear receptors. Biopolymers 91:10, pages 884-894.
Crossref
Holly A. LaVoie & Steven R. King. (2009) Transcriptional Regulation of Steroidogenic Genes: STARD1, CYP11A1 and HSD3B. Experimental Biology and Medicine 234:8, pages 880-907.
Crossref
Takashi Shimizu, Natsuko Sudo, Hiromichi Yamashita, Chiaki Murayama, Hitoshi Miyazaki & Akio Miyamoto. (2009) Histone H3 acetylation of StAR and decrease in DAX-1 is involved in the luteinization of bovine granulosa cells during in vitro culture. Molecular and Cellular Biochemistry 328:1-2, pages 41-47.
Crossref
Olfa Khalfallah, Matthieu Rouleau, Pascal Barbry, Barbara Bardoni & Enzo Lalli. (2009) Dax-1 Knockdown in Mouse Embryonic Stem Cells Induces Loss of Pluripotency and Multilineage Differentiation. Stem Cells 27:7, pages 1529-1537.
Crossref
Kenji Ohe, Katherine T. Tamai, Martti Parvinen & Paolo Sassone-Corsi. (2009) DAX-1 and SOX6 molecular interplay results in an antagonistic effect in pre-mRNA splicing. Developmental Dynamics 238:6, pages 1595-1604.
Crossref
Carrie L. Partch, Paul B. Card, Carlos A. Amezcua & Kevin H. Gardner. (2009) Molecular Basis of Coiled Coil Coactivator Recruitment by the Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT). Journal of Biological Chemistry 284:22, pages 15184-15192.
Crossref
Hsiang-Tsan Hsieh, Chih-Hung Wang, Mei-Ling Wu, Feng-Ming Yang, Yu-Chen Tai & Meng-Chun Hu. (2009) PIASy inhibits LRH-1-dependent CYP11A1 expression by competing for SRC-1 binding . Biochemical Journal 419:1, pages 201-209.
Crossref
Feng-Ming Yang, Chien-Ting Pan, Huei-Man Tsai, Tai-Wei Chiu, Mei-Ling Wu & Meng-Chun Hu. (2009) Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cells. FEBS Journal 276:2, pages 425-436.
Crossref
Elena P. Sablin, April Woods, Irina N. Krylova, Peter Hwang, Holly A. Ingraham & Robert J. Fletterick. (2008) The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1. Proceedings of the National Academy of Sciences 105:47, pages 18390-18395.
Crossref
Junguo Zhou, Robert H. Oakley & John A. Cidlowski. (2008) DAX-1 (Dosage-Sensitive Sex Reversal-Adrenal Hypoplasia Congenita Critical Region on the X-Chromosome, Gene 1) Selectively Inhibits Transactivation But Not Transrepression Mediated by the Glucocorticoid Receptor in a LXXLL-Dependent Manner. Molecular Endocrinology 22:7, pages 1521-1534.
Crossref
Sofia Burendahl, Eckardt Treuter & Lennart Nilsson. (2008) Molecular Dynamics Simulations of Human LRH-1: The Impact of Ligand Binding in a Constitutively Active Nuclear Receptor. Biochemistry 47:18, pages 5205-5215.
Crossref
Gwang Sik Kim, Gha Young Lee, Balachandar Nedumaran, Yun-Yong Park, Kyung Tae Kim, Sang Chul Park, Young Chul Lee, Jae Bum Kim & Hueng-Sik Choi. (2008) The orphan nuclear receptor DAX-1 acts as a novel transcriptional corepressor of PPARγ. Biochemical and Biophysical Research Communications 370:2, pages 264-268.
Crossref
Sharmistha DasMatthieu SchapiraMarjana Tomic-Canic, Ritu GoyankaTimothy CardozoHerbert H. Samuels. (2007) Farnesyl Pyrophosphate Is a Novel Transcriptional Activator for a Subset of Nuclear Hormone Receptors. Molecular Endocrinology 21:11, pages 2672-2686.
Crossref
Qing ZhouHiram Chipperfield, Douglas A. Melton & Wing Hung Wong. (2007) A gene regulatory network in mouse embryonic stem cells. Proceedings of the National Academy of Sciences 104:42, pages 16438-16443.
Crossref
Masatoshi Nakamoto, De-Shou Wang, Aya Suzuki, Masaru Matsuda, Yoshitaka Nagahama & Naoki Shibata. (2007) Dax1 suppressesP450arom expression in medaka ovarian follicles. Molecular Reproduction and Development 74:10, pages 1239-1246.
Crossref
Anita K. Iyer, Yao-Hua Zhang & Edward R.B. McCabe. (2007) LXXLL motifs and AF-2 domain mediate SHP (NR0B2) homodimerization and DAX1 (NR0B1)–DAX1A heterodimerization. Molecular Genetics and Metabolism 92:1-2, pages 151-159.
Crossref
De-Shou WangTohru KobayashiLin-Yan ZhouBindhu Paul-PrasanthShigeho IjiriFumie SakaiKataaki OkuboKen-ichirou Morohashi & Yoshitaka Nagahama. (2007) Foxl2 Up-Regulates Aromatase Gene Transcription in a Female-Specific Manner by Binding to the Promoter as Well as Interacting with Ad4 Binding Protein/Steroidogenic Factor 1. Molecular Endocrinology 21:3, pages 712-725.
Crossref
A. A. Verrijn Stuart, G. Ozisik, M. A. de Vroede, J. C. Giltay, R. J. Sinke, T. J. Peterson, R. M. Harris, J. Weiss & J. L. Jameson. (2007) An Amino-Terminal DAX1 ( NROB1 ) Missense Mutation Associated with Isolated Mineralocorticoid Deficiency . The Journal of Clinical Endocrinology & Metabolism 92:3, pages 755-761.
Crossref
Jian Guo, Shi-Xin Tao, Min Chen, Yu-Qiang Shi, Zhu-Qiang Zhang, Yin-Chuan Li, Xue-Sen Zhang, Zhao-Yuan Hu & Yi-Xun Liu. (2007) Heat Treatment Induces Liver Receptor Homolog-1 Expression in Monkey and Rat Sertoli Cells. Endocrinology 148:3, pages 1255-1265.
Crossref
Deeksha Saxena, Rosalba Escamilla-Hernandez, Lynda Little-Ihrig & Anthony J. Zeleznik. (2007) Liver Receptor Homolog-1 and Steroidogenic Factor-1 Have Similar Actions on Rat Granulosa Cell Steroidogenesis. Endocrinology 148:2, pages 726-734.
Crossref
Edward R.B. McCabe. (2007) DAX1: Increasing complexity in the roles of this novel nuclear receptor. Molecular and Cellular Endocrinology 265-266, pages 179-182.
Crossref
Dagmar Wilhelm, Stephen Palmer & Peter Koopman. (2007) Sex Determination and Gonadal Development in Mammals. Physiological Reviews 87:1, pages 1-28.
Crossref
Yong‐Soo Lee, Dipanjan Chanda, Jeonggu Sim, Yun‐Yong Park & Hueng‐Sik Choi. 2007. 117 158 .
Gérard Benoit, Austin Cooney, Vincent Giguere, Holly Ingraham, Mitch Lazar, George Muscat, Thomas Perlmann, Jean-Paul Renaud, John Schwabe, Frances Sladek, Ming-Jer Tsai & Vincent Laudet. (2006) International Union of Pharmacology. LXVI. Orphan Nuclear Receptors. Pharmacological Reviews 58:4, pages 798-836.
Crossref
Anita K. Iyer, Yao-Hua Zhang & Edward R. B. McCabe. (2006) Dosage-Sensitive Sex Reversal Adrenal Hypoplasia Congenita Critical Region on the X Chromosome, Gene 1 (DAX1) (NR0B1) and Small Heterodimer Partner (SHP) (NR0B2) Form Homodimers Individually, as Well as DAX1-SHP Heterodimers. Molecular Endocrinology 20:10, pages 2326-2342.
Crossref
Shui-Liang WANG, Feng-Hua LAN, Yue-Peng ZHUANG, Hui-Zhong LI, Liang-Hu HUANG, De-Zhu ZHENG, Jian ZENG, Li-Hong DONG, Zhong-Yong ZHU & Ji-Liang FU. (2006) Microarray Analysis of Gene-Expression Profile in Hepatocellular Carcinoma Cell, BEL-7402, with Stable Suppression of hLRH-1 via a DNA Vector-based RNA Interference. Acta Genetica Sinica 33:10, pages 881-891.
Crossref
Pascal Bernard, Louisa Ludbrook, Gloria Queipo, Mary-Beth Dinulos, Gad B. Kletter, Yao-Hua Zhang, James K. Phelan, Edward R.B. McCabe, Vincent R. Harley & Eric Vilain. (2006) A familial missense mutation in the hinge region of DAX1 associated with late-onset AHC in a prepubertal female. Molecular Genetics and Metabolism 88:3, pages 272-279.
Crossref
Jennifer Weck & Kelly E. Mayo. (2006) Switching of NR5A Proteins Associated with the Inhibin α-Subunit Gene Promoter after Activation of the Gene in Granulosa Cells. Molecular Endocrinology 20:5, pages 1090-1103.
Crossref
Leslie Pick, W. Ray Anderson, Jeffrey Shultz & Craig T. Woodard. 2006. Nuclear Receptors in Development. Nuclear Receptors in Development 255 296 .
Rachid Safi, Agnes Kovacic, Stéphanie Gaillard, Yoko Murata, Evan R. Simpson, Donald P. McDonnell & Colin D. Clyne. (2005) Coactivation of Liver Receptor Homologue-1 by Peroxisome Proliferator-Activated Receptor γ Coactivator-1α on Aromatase Promoter II and Its Inhibition by Activated Retinoid X Receptor Suggest a Novel Target for Breast-Specific Antiestrogen Therapy. Cancer Research 65:24, pages 11762-11770.
Crossref
Yong Li, Mihwa Choi, Kelly Suino, Amanda Kovach, Jennifer Daugherty, Steven A. Kliewer & H. Eric Xu. (2005) Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner. Proceedings of the National Academy of Sciences 102:27, pages 9505-9510.
Crossref
Susan Y. Park, Joshua J. Meeks, Gerald Raverot, Liza E. Pfaff, Jeffrey Weiss, Gary D. Hammer & J. Larry Jameson. (2005) Nuclear receptors Sf1 and Dax1 function cooperatively to mediate somatic cell differentiation during testis development. Development 132:10, pages 2415-2423.
Crossref
Rakesh Kumar, Anupama E. Gururaj, Ratna K. Vadlamudi & Suresh K. Rayala. (2005) The Clinical Relevance of Steroid Hormone Receptor Corepressors. Clinical Cancer Research 11:8, pages 2822-2831.
Crossref
Jamie M.R. Moore & R.Kiplin Guy. (2005) Coregulator Interactions with the Thyroid Hormone Receptor. Molecular & Cellular Proteomics 4:4, pages 475-482.
Crossref
Eric A Ortlund, Yoonkwang Lee, Isaac H Solomon, Janet M Hager, Rachid Safi, Yunhee Choi, Ziqiang Guan, Ashutosh Tripathy, Christian R H Raetz, Donald P McDonnell, David D Moore & Matthew R Redinbo. (2005) Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP. Nature Structural & Molecular Biology 12:4, pages 357-363.
Crossref
Joung W. Kim, Jon C. Havelock, Bruce R. Carr & George R. Attia. (2005) The Orphan Nuclear Receptor, Liver Receptor Homolog-1, Regulates Cholesterol Side-Chain Cleavage Cytochrome P450 Enzyme in Human Granulosa Cells. The Journal of Clinical Endocrinology & Metabolism 90:3, pages 1678-1685.
Crossref
Karla J. Saner, Takashi Suzuki, Hironobu Sasano, John Pizzey, Clement Ho, Jerome F. StraussIIIIII, Bruce R. Carr & William E. Rainey. (2005) Steroid Sulfotransferase 2A1 Gene Transcription Is Regulated by Steroidogenic Factor 1 and GATA-6 in the Human Adrenal. Molecular Endocrinology 19:1, pages 184-197.
Crossref
Wei-Yi Chen, Wen-Chih Lee, Nai-Chi Hsu, Fu Huang & Bon-chu Chung. (2004) SUMO Modification of Repression Domains Modulates Function of Nuclear Receptor 5A1 (Steroidogenic Factor-1). Journal of Biological Chemistry 279:37, pages 38730-38735.
Crossref
Anita K. Iyer & Edward R.B. McCabe. (2004) Molecular mechanisms of DAX1 action. Molecular Genetics and Metabolism 83:1-2, pages 60-73.
Crossref
Kara L. Britt, Peter G. Stanton, Marie Misso, Evan R. Simpson & Jock K. Findlay. (2004) The Effects of Estrogen on the Expression of Genes Underlying the Differentiation of Somatic Cells in the Murine Gonad. Endocrinology 145:8, pages 3950-3960.
Crossref
Jamie M.R. Moore, Sarah J. Galicia, Andrea C. McReynolds, Ngoc-Ha Nguyen, Thomas S. Scanlan & R. Kiplin Guy. (2004) Quantitative Proteomics of the Thyroid Hormone Receptor-Coregulator Interactions. Journal of Biological Chemistry 279:26, pages 27584-27590.
Crossref
Yun-Yong Park, Han-Jong Kim, Joon-Young Kim, Mi-Young Kim, Kwang-Hoon Song, Ki Cheol Park, Kang-Yeol Yu, Minho Shong, Kyoung-Hee Kim & Hueng-Sik Choi. (2004) Differential Role of the Loop Region between Helices H6 and H7 within the Orphan Nuclear Receptors Small Heterodimer Partner and DAX-1. Molecular Endocrinology 18:5, pages 1082-1095.
Crossref
Vincenzo Pezzi, Rosa Sirianni, Adele Chimento, Marcello Maggiolini, Sonia Bourguiba, Christelle Delalande, Serge Carreau, Sebastiano Andò, Evan R. Simpson & Colin D. Clyne. (2004) Differential Expression of Steroidogenic Factor-1/Adrenal 4 Binding Protein and Liver Receptor Homolog-1 (LRH-1)/Fetoprotein Transcription Factor in the Rat Testis: LRH-1 as a Potential Regulator of Testicular Aromatase Expression. Endocrinology 145:5, pages 2186-2196.
Crossref
Elisabeth Fayard, Johan Auwerx & Kristina Schoonjans. (2004) LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis. Trends in Cell Biology 14:5, pages 250-260.
Crossref
Colin D. Clyne, Agnes Kovacic, Caroline J. Speed, Jiong Zhou, Vincenzo Pezzi & Evan R. Simpson. (2004) Regulation of aromatase expression by the nuclear receptor LRH-1 in adipose tissue. Molecular and Cellular Endocrinology 215:1-2, pages 39-44.
Crossref
Ying Zhang & Maria L Dufau. 2004. Nuclear Receptor Coregulators. Nuclear Receptor Coregulators 1 48 .
Pulak R Manna, Xing-Jia Wang & Douglas M Stocco. (2003) Involvement of multiple transcription factors in the regulation of steroidogenic acute regulatory protein gene expression. Steroids 68:14, pages 1125-1134.
Crossref
Robert Clipsham & Edward R.B McCabe. (2003) DAX1 and its network partners: exploring complexity in development. Molecular Genetics and Metabolism 80:1-2, pages 81-120.
Crossref
Enzo Lalli & Paolo Sassone-Corsi. (2003) DAX-1, an Unusual Orphan Receptor at the Crossroads of Steroidogenic Function and Sexual Differentiation. Molecular Endocrinology 17:8, pages 1445-1453.
Crossref
Kaname Kawajiri, Togo Ikuta, Taiga Suzuki, Masatomo Kusaka, Masami Muramatsu, Kenji Fujieda, Masayoshi Tachibana & Ken-ichirou Morohashi. (2003) Role of the LXXLL-Motif and Activation Function 2 Domain in Subcellular Localization of Dax-1 (Dosage-Sensitive Sex Reversal-Adrenal Hypoplasia Congenita Critical Region on the X Chromosome, Gene 1). Molecular Endocrinology 17:6, pages 994-1004.
Crossref
Elena P. Sablin, Irina N. Krylova, Robert J. Fletterick & Holly A. Ingraham. (2003) Structural Basis for Ligand-Independent Activation of the Orphan Nuclear Receptor LRH-1. Molecular Cell 11:6, pages 1575-1585.
Crossref
Hirofumi Mizusaki, Ken Kawabe, Tokuo Mukai, Etsuko Ariyoshi, Megumi Kasahara, Hidefumi Yoshioka, Amanda Swain & Ken-ichirou Morohashi. (2003) Dax-1 (Dosage-Sensitive Sex Reversal-Adrenal Hypoplasia Congenita Critical Region on the X Chromosome, Gene 1) Gene Transcription Is Regulated by Wnt4 in the Female Developing Gonad. Molecular Endocrinology 17:4, pages 507-519.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.