Citations (130)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (9)
Jeffrey Q. Nguyen & Rosalyn B. Irby. (2017) TRIM21 is a novel regulator of Par-4 in colon and pancreatic cancer cells. Cancer Biology & Therapy 18:1, pages 16-25.
Read now
Read now
Rosalyn B Irby & Christina LB Kline. (2013) Par-4 as a potential target for cancer therapy. Expert Opinion on Therapeutic Targets 17:1, pages 77-87.
Read now
Read now
Markus David Siegelin. (2012) Utilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis. Expert Opinion on Therapeutic Targets 16:8, pages 801-817.
Read now
Read now
Filippo P. D'Andrea, Michael R. Horsman, Moustapha Kassem, Jens Overgaard & Akmal Safwat. (2012) Tumourigenicity and radiation resistance of mesenchymal stem cells. Acta Oncologica 51:5, pages 669-679.
Read now
Read now
Parvesh Chaudhry, Mohan Singh, Sophie Parent & Eric Asselin. (2012) Prostate Apoptosis Response 4 (Par-4), a Novel Substrate of Caspase-3 during Apoptosis Activation. Molecular and Cellular Biology 32:4, pages 826-839.
Read now
Read now
Gang Cheng, Marcos Lopez, Jacek Zielonka, Andrew D. Hauser, Joy Joseph, Donna McAllister, J. Jordi Rowe, Sonia L. Sugg, Carol L. Williams & Balaraman Kalyanaraman. (2011) Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells. Cancer Biology & Therapy 12:8, pages 707-717.
Read now
Read now
Asfar S Azmi, Philip A Philip, Syed F Zafar, Fazlul H Sarkar & Ramzi M Mohammad. (2010) PAR-4 as a possible new target for pancreatic cancer therapy. Expert Opinion on Therapeutic Targets 14:6, pages 611-620.
Read now
Read now
Howard Donninger, Luke Hesson, Michele Vos, Kristin Beebe, Laura Gordon, David Sidransky, Jun Wei Liu, Thomas Schlegel, Shannon Payne, Arndt Hartmann, Farida Latif & Geoffrey J. Clark. (2010) The Ras Effector RASSF2 Controls the PAR-4 Tumor Suppressor. Molecular and Cellular Biology 30:11, pages 2608-2620.
Read now
Read now
Sushma Gurumurthy, Anindya Goswami, Krishna Murthi Vasudevan & Vivek M. Rangnekar. (2005) Phosphorylation of Par-4 by Protein Kinase A Is Critical for Apoptosis. Molecular and Cellular Biology 25:3, pages 1146-1161.
Read now
Read now
Articles from other publishers (121)
Min Tang, Leilei Zhai, Juanjuan Chen, Feng Wang, Haimin Chen & Wei Wu. (2023) The Antitumor Potential of λ-Carrageenan Oligosaccharides on Gastric Carcinoma by Immunomodulation. Nutrients 15:9, pages 2044.
Crossref
Crossref
Samjhana Pandey, Krishna K. Raut, Andrea M. Clark, Antoine Baudin, Lamya Djemri, David S. Libich, Komala Ponniah & Steven M. Pascal. (2023) Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis. Biomolecules 13:4, pages 667.
Crossref
Crossref
Paul Eggleton, Jorge De Alba, Michael Weinreich, Perry Calias, Roly Foulkes & Valerie M. Corrigall. (2023) The therapeutic mavericks: Potent immunomodulating chaperones capable of treating human diseases. Journal of Cellular and Molecular Medicine 27:3, pages 322-339.
Crossref
Crossref
Nathalia Araujo, James Sledziona, Sunil K. Noothi, Ravshan Burikhanov, Nikhil Hebbar, Saptadwipa Ganguly, Tripti Shrestha-Bhattarai, Beibei Zhu, Wendy S. Katz, Yi Zhang, Barry S. Taylor, Jinze Liu, Li Chen, Heidi L. Weiss, Daheng He, Chi Wang, Andrew J. Morris, Lisa A. Cassis, Mariana Nikolova-Karakashian, Prabhakar R. Nagareddy, Olle Melander, B. Mark Evers, Philip A. Kern & Vivek M. Rangnekar. (2022) Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity. Frontiers in Oncology 12.
Crossref
Crossref
Jian Zhang, Wanyuan Dong, Yuhong Ren & Dongzhi Wei. (2022) SAC-TRAIL, a novel anticancer fusion protein: expression, purification, and functional characterization. Applied Microbiology and Biotechnology 106:4, pages 1511-1520.
Crossref
Crossref
Vanessa Mylenna Florêncio de Carvalho, Priscilla Stela Santana de Oliveira, Simão Kalebe Silva de Paula, Amanda Pinheiro de Barros Albuquerque, Moacyr Jesus Barreto de Melo Rêgo, Maira Galdino da Rocha Pitta & Michelly Cristiny Pereira. (2022) Vitamin D Modulates PAR-4 Expression in an in Vitro Model of Osteoarthritis. Brazilian Archives of Biology and Technology 65.
Crossref
Crossref
Daniel Bastida-Ruiz, Alexia Childress & Marie Cohen. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
209
238
.
Margaux Sevin, John E. Eriksson, Valérie Mezger, Carmen Garrido & Aurélie de Thonel. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
185
208
.
J. Labahn & U. K. Tiruttani Subhramanyam. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
127
150
.
David S. Libich, Samjhana Pandey & Steven M. Pascal. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
95
126
.
Yanquan Zhang, Fengyi Mao & Xiaoqi Liu. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
61
93
.
Sehamuddin Galadari, Anees Rahman Cheratta & Faisal Thayyullathil. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
263
291
.
Saptadwipa Ganguly, Ravshan Burikhanov, Shirley Qiu & Vivek M. Rangnekar. 2022. Tumor Suppressor Par-4. Tumor Suppressor Par-4
1
59
.
Piotr K. Zakrzewski. (2021) Canonical TGFβ Signaling and Its Contribution to Endometrial Cancer Development and Progression—Underestimated Target of Anticancer Strategies. Journal of Clinical Medicine 10:17, pages 3900.
Crossref
Crossref
Krishna Raut, Komala Ponniah & Steven Pascal. (2021) Structural Analysis of the cl-Par-4 Tumor Suppressor as a Function of Ionic Environment. Biomolecules 11:3, pages 386.
Crossref
Crossref
Anees Rahman Cheratta, Faisal Thayyullathil, Siraj Pallichankandy, Karthikeyan Subburayan, Ameer Alakkal & Sehamuddin Galadari. (2021) Prostate apoptosis response-4 and tumor suppression: it’s not just about apoptosis anymore. Cell Death & Disease 12:1.
Crossref
Crossref
Luna Acharya, Hariharasudan Mani, Aman Ullah, Sana Hussain, Saeed Ali & Sarfraz Ahmad. 2021. Overcoming Drug Resistance in Gynecologic Cancers. Overcoming Drug Resistance in Gynecologic Cancers
49
75
.
Rupinder Kaur Sodhi, Amarjot Kaur Grewal, Jitender Madan, Thakur Gurjeet Singh Jhajj & Rishab Kumar. 2021. Clinical Perspectives and Targeted Therapies in Apoptosis. Clinical Perspectives and Targeted Therapies in Apoptosis
217
283
.
Joseph T. Greene, Mary K. McKenna, Subbarao Bondada & Natarajan Muthusamy. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
149
159
.
Sunil K. Noothi, Mary K. McKenna, Sara S. Alhakeem, James P. Collard, J. T. Greene, Natarajan Muthusamy, Vivek M. Rangnekar & Subbarao Bondada. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
133
148
.
Simone Aparecida de Bessa-Garcia & Maria Aparecida Nagai. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
113
131
.
Jeevan Ghosalkar, Vinay Sonawane, Mohsina Khan, Kalpana Joshi & Padma Shastry. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
77
111
.
Seema Gupta, Amogh Narendra, Satvik Lolla, Muskan Qureshi, Muhammad Hamza Qureshi & Mansoor M. Ahmed. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
69
76
.
Rosalyn B. Irby, Christina Leah B. Kline & Arun K. Sharma. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
59
68
.
François Fabi, Pascal Adam & Eric Asselin. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
41
58
.
Ravshan Burikhanov & Vivek M. Rangnekar. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
313
320
.
Peng Wang & Zhonglin Hao. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
303
311
.
Nadia El-Guendy. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
25
40
.
Nathalia Araujo, Nikhil Hebbar & Vivek M. Rangnekar. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
289
301
.
Lu Ren & Shaolin Shi. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
281
288
.
Tahseen Ahmed, Tuneer Ranjan Mallick, Michael A. Walter & Moulinath Acharya. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
255
267
.
Qing Guo, Jun Xie & Chelsea J. Guo. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
215
245
.
Fang Zheng & Chang-Guo Zhan. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
191
201
.
Vitaliy M. Sviripa, Ravshan Burikhanov, Chunming Liu & David S. Watt. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
171
189
.
Mir Mohd Faheem, Archana Katoch & Anindya Goswami. 2021. Tumor Suppressor Par-4. Tumor Suppressor Par-4
1
23
.
Syed Mudabir Ahmad, Debasis Nayak, Khalid Bashir Mir, Mir Mohd Faheem, Shah Nawaz, Govind Yadav & Anindya Goswami. (2020) Par-4 activation restrains EMT-induced chemoresistance in PDAC by attenuating MDM-2. Pancreatology 20:8, pages 1698-1710.
Crossref
Crossref
Hui Han, Huimin Li & Juan Zhou. (2020) Long non-coding RNA MIR503HG inhibits the proliferation, migration and invasion of colon cancer cells via miR-107/Par4 axis. Experimental Cell Research 395:2, pages 112205.
Crossref
Crossref
Leonardo Y. TanakaPercillia V.S. OliveiraFrancisco R.M. Laurindo. (2020) Peri/Epicellular Thiol Oxidoreductases as Mediators of Extracellular Redox Signaling. Antioxidants & Redox Signaling 33:4, pages 280-307.
Crossref
Crossref
Faisal Thayyullathil, Anees Rahman Cheratta, Siraj Pallichankandy, Karthikeyan Subburayan, Saeed Tariq, Vivek M. Rangnekar & Sehamuddin Galadari. (2020) Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:7, pages 118692.
Crossref
Crossref
Kyungbo Kim, Pereira Araujo, Nikhil Hebbar, Ziyuan Zhou, Xirong Zheng, Fang Zheng, Vivek M Rangnekar & Chang-Guo Zhan. (2019) Development of a novel prostate apoptosis response-4 (Par-4) protein entity with an extended duration of action for therapeutic treatment of cancer. Protein Engineering, Design and Selection 32:3, pages 159-166.
Crossref
Crossref
Andrea M. Clark, Komala Ponniah, Meghan S. Warden, Emily M. Raitt, Benjamin G. Smith & Steven M. Pascal. (2019) Tetramer formation by the caspase‐activated fragment of the Par‐4 tumor suppressor. The FEBS Journal 286:20, pages 4060-4073.
Crossref
Crossref
Debasis Nayak, Archana Katoch, Deepak Sharma, Mir Mohd. Faheem, Souneek Chakraborty, Promod Kumar Sahu, Naveed Anjum Chikan, Hina Amin, Ajai Prakash Gupta, Sumit G. Gandhi, Debaraj Mukherjee & Anindya Goswami. (2019) Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78. Breast Cancer Research and Treatment 177:2, pages 307-323.
Crossref
Crossref
Haihong Guo, Fabian Treude, Oliver H. Krämer, Bernhard Lüscher & Jörg Hartkamp. (2019) PAR-4 overcomes chemo-resistance in breast cancer cells by antagonizing cIAP1. Scientific Reports 9:1.
Crossref
Crossref
Yu-Hsuan Lee, Yu-Ying Chen, Ya-Ling Yeh, Ying-Jan Wang & Rong-Jane Chen. (2019) Stilbene Compounds Inhibit Tumor Growth by the Induction of Cellular Senescence and the Inhibition of Telomerase Activity. International Journal of Molecular Sciences 20:11, pages 2716.
Crossref
Crossref
J. T. Greene, Rajeswaran Mani, Rahul Ramaswamy, Frank Frissora, Max Yano, Kevan Zapolnik, Bonnie Harrington, Ronni Wasmuth, Minh Tran, Xiaokui Mo, Mary McKenna, Vivek M. Rangnekar, John C. Byrd, Subbarao Bondada & Natarajan Muthusamy. (2019) Par-4 overexpression impedes leukemogenesis in the Eµ-TCL1 leukemia model through downregulation of NF-κB signaling. Blood Advances 3:8, pages 1255-1266.
Crossref
Crossref
Renata Virgínia Cavalcanti Santos, Wanessa Layssa Batista de Sena, Flaviana Alves dos Santos, Antônio Felix da Silva Filho, Marina Galdino da Rocha Pitta, Maira Galdino da Rocha Pitta, Moacyr Barreto de Melo Rego & Michelly Cristiny Pereira. (2019) Potential Therapeutic Agents Against Par-4 Target for Cancer Treatment: Where Are We Going?. Current Drug Targets 20:6, pages 635-654.
Crossref
Crossref
Sonica Chaudhry, Vibhor Joshi, Naveen Bojjireddy, Maikho Thoh, Santosh K. Sandur & Gosukonda Subrahmanyam. (2019) Silencing of type II phosphatidylinositol 4-kinase β stabilizes prostate apoptosis response-4 and induces apoptosis in cancer cells. Biochemical Journal 476:2, pages 405-419.
Crossref
Crossref
Andrea Clark, Komala Ponniah, Meghan Warden, Emily Raitt, Andrea Yawn & Steven Pascal. (2018) pH-Induced Folding of the Caspase-Cleaved Par-4 Tumor Suppressor: Evidence of Structure Outside of the Coiled Coil Domain. Biomolecules 8:4, pages 162.
Crossref
Crossref
Peng Wang, Ravshan Burikhanov, Rani Jayswal, Heidi L. Weiss, Susanne M. Arnold, John L. Villano & Vivek M. Rangnekar. (2018) Neoadjuvant administration of hydroxychloroquine in a phase 1 clinical trial induced plasma Par-4 levels and apoptosis in diverse tumors. Genes & Cancer 9:5-6, pages 190-197.
Crossref
Crossref
Karthikeyan Subburayan, Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman & Sehamuddin Galadari. (2018) Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells. Cancer Letters 426, pages 80-97.
Crossref
Crossref
Mary K. McKenna, Sunil K. Noothi, Sara S. Alhakeem, Karine Z. Oben, Joseph T. Greene, Rajeswaran Mani, Kathryn L. PerryJames P. Collard, Jacqueline R. Rivas, Gerhard C. Hildebrandt, Roger A. Fleischman, Eric B. Durbin, John C. Byrd, Chi Wang, Natarajan Muthusamy, Vivek M. RangnekarSubbarao Bondada. (2018) Novel role of prostate apoptosis response-4 tumor suppressor in B-cell chronic lymphocytic leukemia. Blood 131:26, pages 2943-2954.
Crossref
Crossref
Jian Zhang, Aiyou Sun, Yuguo Dong & Dongzhi Wei. (2017) Recombinant Production and Characterization of SAC, the Core Domain of Par-4, by SUMO Fusion System. Applied Biochemistry and Biotechnology 184:4, pages 1155-1167.
Crossref
Crossref
Yuan-Li Tsai & Amy S. Lee. 2018. Cell Surface GRP78, a New Paradigm in Signal Transduction Biology. Cell Surface GRP78, a New Paradigm in Signal Transduction Biology
41
62
.
Ganesh Shelke, Jayashree Jagtap, Dae-Kyum Kim, Reecha Shah, Gowry Das, Mruthyunjaya Shivayogi, Radha Pujari & Padma Shastry. (2017) TNF-α and IFN-γ Together Up-Regulates Par-4 Expression and Induce Apoptosis in Human Neuroblastomas. Biomedicines 6:1, pages 4.
Crossref
Crossref
Udaya K Tiruttani Subhramanyam, Jan Kubicek, Ulf B Eidhoff & Joerg Labahn. (2017) Structural basis for the regulatory interactions of proapoptotic Par-4. Cell Death & Differentiation 24:9, pages 1540-1547.
Crossref
Crossref
Nikhil Hebbar, Ravshan Burikhanov, Nidhi Shukla, Shirley Qiu, Yanming Zhao, Kojo S.J. Elenitoba-Johnson & Vivek M. Rangnekar. (2017) A Naturally Generated Decoy of the Prostate Apoptosis Response-4 Protein Overcomes Therapy Resistance in Tumors. Cancer Research 77:15, pages 4039-4050.
Crossref
Crossref
Kevin Brasseur, Nicolas Gévry & Eric Asselin. (2016) Chemoresistance and targeted therapies in ovarian and endometrial cancers. Oncotarget 8:3, pages 4008-4042.
Crossref
Crossref
James Sledziona & Vivek M. Rangnekar. 2017. TRAIL, Fas Ligand, TNF and TLR3 in Cancer. TRAIL, Fas Ligand, TNF and TLR3 in Cancer
91
106
.
Reyaz Ur Rasool, Debasis Nayak, Souneek Chakraborty, Archana Katoch, Mir Mohd Faheem, Hina Amin & Anindya Goswami. (2016) A journey beyond apoptosis: new enigma of controlling metastasis by pro-apoptotic Par-4. Clinical & Experimental Metastasis 33:8, pages 757-764.
Crossref
Crossref
Ye Su, Haijiang Wu, Alexander Pavlosky, Ling-Lin Zou, Xinna Deng, Zhu-Xu Zhang & Anthony M Jevnikar. (2016) Regulatory non-coding RNA: new instruments in the orchestration of cell death. Cell Death & Disease 7:8, pages e2333-e2333.
Crossref
Crossref
Kevin Brasseur, François Fabi, Pascal Adam, Sophie Parent, Laurent Lessard & Eric Asselin. (2016) Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells. Oncotarget 7:24, pages 36971-36987.
Crossref
Crossref
KAI YANG, JIE SHEN, SHAN-WEN CHEN, JIE QIN, XIANG-YI ZHENG & LI-PING XIE. (2016) Upregulation of PAWR by small activating RNAs induces cell apoptosis in human prostate cancer cells. Oncology Reports 35:4, pages 2487-2493.
Crossref
Crossref
Shayan Sarkar, Sumeet Jain, Vineeta Rai, Dipak K. Sahoo, Sumita Raha, Sujit Suklabaidya, Shantibhusan Senapati, Vivek M. Rangnekar, Indu B. Maiti & Nrisingha Dey. (2015) Plant-derived SAC domain of PAR-4 (Prostate Apoptosis Response 4) exhibits growth inhibitory effects in prostate cancer cells. Frontiers in Plant Science 6.
Crossref
Crossref
Sonia Meynier, Marianne Kramer, Pascale Ribaux, Jean-Christophe Tille, Florence Delie, Patrick Petignat & Marie Cohen. (2015) Role of PAR-4 in ovarian cancer. Oncotarget 6:26, pages 22641-22652.
Crossref
Crossref
Seon Min Woo & Taeg Kyu Kwon. (2015) Prostate Apoptosis Response-4 (Par-4) as a Cancer Therapeutic Target. Journal of Life Science 25:8, pages 947-952.
Crossref
Crossref
Kevin Brasseur, Pascal Auger, Eric Asselin, Sophie Parent, Jean-Charles Côté & Marc Sirois. (2015) Parasporin-2 from a New Bacillus thuringiensis 4R2 Strain Induces Caspases Activation and Apoptosis in Human Cancer Cells. PLOS ONE 10:8, pages e0135106.
Crossref
Crossref
Osman SalisAbdulkerim BedirSedat GultenAli OkuyucuCanan KulcuHasan Alacam. (2014)
Cytotoxic Effect of Fluvastatin on MCF-7 Cells Possibly Through a Reduction of the mRNA Expression Levels of
SGK1
and
CAV1
. Cancer Biotherapy and Radiopharmaceuticals 29:9, pages 368-375.
Crossref
Crossref
Yinxing Liu, Misty R. Gilbert, Natasha Kyprianou, Vivek M. Rangnekar & Craig Horbinski. (2014) The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells. Acta Neuropathologica 128:5, pages 723-732.
Crossref
Crossref
X Chen, A A Sahasrabuddhe, P Szankasi, F Chung, V Basrur, V M Rangnekar, M Pagano, M S Lim & K S J Elenitoba-Johnson. (2014) Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival. Cell Death & Differentiation 21:10, pages 1535-1545.
Crossref
Crossref
Udaya Kumar Tiruttani Subhramanyam, Jan Kubicek, Ulf B. Eidhoff & Joerg Labahn. (2014) Cloning, expression, purification, crystallization and preliminary crystallographic analysis of the C-terminal domain of Par-4 (PAWR). Acta Crystallographica Section F Structural Biology Communications 70:9, pages 1224-1227.
Crossref
Crossref
Natalia Volodko, Marilyn Gordon, Mohamed Salla, Haya Abu Ghazaleh & Shairaz Baksh. (2014) RASSF tumor suppressor gene family: Biological functions and regulation. FEBS Letters 588:16, pages 2671-2684.
Crossref
Crossref
Fabian Treude, Ferdinand Kappes, Dirk Fahrenkamp, Gerhard Müller-Newen, Federico Dajas-Bailador, Oliver H. Krämer, Bernhard Lüscher & Jörg Hartkamp. (2014) Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis. Oncotarget 5:10, pages 2988-2998.
Crossref
Crossref
P Chaudhry, F Fabi, M Singh, S Parent, V Leblanc & E Asselin. (2014) Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition. Cell Death & Disease 5:2, pages e1044-e1044.
Crossref
Crossref
Ling-Jung Wang, Peir-Rong Chen, Lee-Ping Hsu, Wen-Lin Hsu, Dai-Wei Liu, Chung-Hsing Chang, Yih-Chih Hsu & Jeng-Woei Lee. (2014) Concomitant Induction of Apoptosis and Autophagy by Prostate Apoptosis Response-4 in Hypopharyngeal Carcinoma Cells. The American Journal of Pathology 184:2, pages 418-430.
Crossref
Crossref
A de Thonel, A Hazoumé, V Kochin, K Isoniemi, G Jego, E Fourmaux, A Hammann, H Mjahed, O Filhol, O Micheau, P Rocchi, V Mezger, J E Eriksson, V M Rangnekar & C Garrido. (2014) Regulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cells. Cell Death & Disease 5:1, pages e1016-e1016.
Crossref
Crossref
William W. Du, Xianmin Li, Tianbi Li, Haoran Li, Anna Khorshidi & Burton B Yang. (2014) Expression of microRNA miR-17-3p inhibits mouse cardiac fibroblast senescence by targeting Par4. Journal of Cell Science.
Crossref
Crossref
Jiaxin Tan, Yu You, Tubin Xu, Peng Yu, Dingguo Wu, Hao Deng, Yujun Zhang & Ping Bie. (2014) Par-4 downregulation confers cisplatin resistance in pancreatic cancer cells via PI3K/Akt pathway-dependent EMT. Toxicology Letters 224:1, pages 7-15.
Crossref
Crossref
Faisal Thayyullathil, Anees Rahman, Siraj Pallichankandy, Mahendra Patel & Sehamuddin Galadari. (2014) ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma. FEBS Open Bio 4:1, pages 763-776.
Crossref
Crossref
Nikhil Hebbar, Tripti Shrestha-Bhattarai & Vivek M. Rangnekar. 2014. Anticancer Genes. Anticancer Genes
155
166
.
MICHELLY C. PEREIRA, SIMONE A. DE BESSA-GARCIA, RAVSHAN BURIKHANOV, ANA CAROLINA PAVANELLI, LOURIVAL ANTUNES, VIVEK M. RANGNEKAR & MARIA A. NAGAI. (2013) Prostate apoptosis response-4 is involved in the apoptosis response to docetaxel in MCF-7 breast cancer cells. International Journal of Oncology 43:2, pages 531-538.
Crossref
Crossref
Kai Yang, Jie Shen, Yan-Qi Xie, Yi-Wei Lin, Jie Qin, Qi-Qi Mao, Xiang-Yi Zheng & Li-Ping Xie. (2013) Promoter-targeted double-stranded small RNAs activate PAWR gene expression in human cancer cells. The International Journal of Biochemistry & Cell Biology 45:7, pages 1338-1346.
Crossref
Crossref
Faisal Thayyullathil, Siraj Pallichankandy, Anees Rahman, Jaleel Kizhakkayil, Shahanas Chathoth, Mahendra Patel & Sehamuddin Galadari. (2013) Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells. Journal of Molecular Signaling 8, pages 2.
Crossref
Crossref
Nidhi Shukla, Nikhil K. Hebbar & Vivek M. Rangnekar. 2013. Prostate Cancer. Prostate Cancer
481
495
.
Nikhil Hebbar, Chi Wang & Vivek M. Rangnekar. (2012) Mechanisms of apoptosis by the tumor suppressor Par-4. Journal of Cellular Physiology 227:12, pages 3715-3721.
Crossref
Crossref
Dongxiao Zhuang, Yingchao Liu, Ying Mao, Liang Gao, Haishi Zhang, Shihai Luan, Fengping Huang & Qingquan Li. (2012) TMZ-induced PrPc/par-4 interaction promotes the survival of human glioma cells. International Journal of Cancer 130:2, pages 309-318.
Crossref
Crossref
Deepak K. Sharma, Bilal Rah, Mallikharjuna R. Lambu, Altaf Hussain, Syed K. Yousuf, Anil K. Tripathi, Baldev Singh, Gayatri Jamwal, Zabeer Ahmed, Nayan Chanauria, Amit Nargotra, Anindya Goswami & Debaraj Mukherjee. (2012) Design and synthesis of novel N,N′-glycoside derivatives of 3,3′-diindolylmethanes as potential antiproliferative agents. MedChemComm 3:9, pages 1082.
Crossref
Crossref
Christina Leah B. Kline & Rosalyn B. Irby. (2011) The pro-apoptotic protein Prostate Apoptosis Response Protein-4 (Par-4) can be activated in colon cancer cells by treatment with Src inhibitor and 5-FU. Apoptosis 16:12, pages 1285-1294.
Crossref
Crossref
Simone A. de Bessa Garcia, Michelly C. Pereira & Maria A. Nagai. (2010) Expression Pattern of the Pro-apoptotic Gene PAR-4 During the Morphogenesis of MCF-10A Human Mammary Epithelial Cells. Cancer Microenvironment 4:1, pages 33-38.
Crossref
Crossref
T Shrestha-Bhattarai & V M Rangnekar. (2010) Cancer-selective apoptotic effects of extracellular and intracellular Par-4. Oncogene 29:27, pages 3873-3880.
Crossref
Crossref
Luis Fernando Méndez-López, Pablo Zapata-Benavides, Angel Zavala-Pompa, Miguel Elías Aguado-Barrera, Javier Pacheco-Calleros, Cristina Rodríguez-Padilla, Ricardo Martín Cerda-Flores, Elva Irene Cortés-Gutiérrez & Martha Imelda Dávila-Rodríguez. (2010) Immunohistochemical Analysis of Prostate Apoptosis Response-4 (Par-4) in Mexican Women with Breast Cancer: A Preliminary Study. Archives of Medical Research 41:4, pages 261-268.
Crossref
Crossref
Makoto Saegusa, Miki Hashimura, Takeshi Kuwata & Isao Okayasu. (2010)
Transcriptional regulation of pro-apoptotic
Par-4
by NF-κB/p65 and its function in controlling cell kinetics during early events in endometrial tumourigenesis
. The Journal of Pathology 221:1, pages 26-36.
Crossref
Crossref
Carolina S IlkowSteven D WillowsTom C Hobman. (2010) Rubella virus capsid protein: a small protein with big functions. Future Microbiology 5:4, pages 571-584.
Crossref
Crossref
Tae-Jin Lee, Ji-Hoon Jang, Hyo-Jeong Noh, Eun-Jung Park, Kyeong-Sook Choi & Taeg-Kyu Kwon. (2010) Overexpression of Par-4 sensitizes TRAIL-induced apoptosis via inactivation of NF-κB and Akt signaling pathways in renal cancer cells. Journal of Cellular Biochemistry, pages n/a-n/a.
Crossref
Crossref
Srinivas Koduru, Srinivasan Sowmyalakshmi, Raj Kumar, Rohini Gomathinayagam, Jürgen Rohr & Chendil Damodaran. (2009) Identification of a potent herbal molecule for the treatment of breast cancer. BMC Cancer 9:1.
Crossref
Crossref
Pablo Zapata-Benavides, José L. Méndez-Vázquez, Talina R. González-Rocha, Diana E. Zamora-Avila, Moises A. Franco-Molina, Raúl Garza-Garza & Cristina Rodriguez-Padilla. (2009) Expression of Prostate Apoptosis Response (Par-4) Is Associated with Progesterone Receptor in Breast Cancer. Archives of Medical Research 40:7, pages 595-599.
Crossref
Crossref
Meike BoosenSusanne VetterkindJan Kubicek, Karl-Heinz ScheidtmannSusanne Illenberger & Ute Preuss. (2009) Par-4 Is an Essential Downstream Target of DAP-like Kinase (Dlk) in Dlk/Par-4–mediated Apoptosis. Molecular Biology of the Cell 20:18, pages 4010-4020.
Crossref
Crossref
David S. Libich, Martin Schwalbe, Sachin Kate, Hariprasad Venugopal, Jolyon K. Claridge, Patrick J. B. Edwards, Kaushik Dutta & Steven M. Pascal. (2009) Intrinsic disorder and coiled-coil formation in prostate apoptosis response factor 4. FEBS Journal 276:14, pages 3710-3728.
Crossref
Crossref
Ravshan Burikhanov, Yanming Zhao, Anindya Goswami, Shirley Qiu, Steven R. Schwarze & Vivek M. Rangnekar. (2009) The Tumor Suppressor Par-4 Activates an Extrinsic Pathway for Apoptosis. Cell 138:2, pages 377-388.
Crossref
Crossref
Jeng-Woei Lee, Po-Fan Liu, Lee-Ping Hsu, Peir-Rong Chen, Chung-Hsing Chang & Wen-Ling Shih. (2009) EBV LMP-1 negatively regulates expression and pro-apoptotic activity of Par-4 in nasopharyngeal carcinoma cells. Cancer Letters 279:2, pages 193-201.
Crossref
Crossref
Sunyoung HWANG, Minho MOON, Sehee KIM, Lakkyong HWANG, Kyu Jeung AHN & Seungjoon PARK. (2009) Neuroprotective Effect of Ghrelin Is Associated with Decreased Expression of Prostate Apoptosis Response-4. Endocrine Journal 56:4, pages 609-617.
Crossref
Crossref
Jeng-Woei Lee, Wei-Ting Hsiao, Kuei-Fang Lee, Lai-Fa Sheu, Hsue-Yin Hsu, Lee-Ping Hsu, Borcherng Su, Moon-Sing Lee, Yih-Chih Hsu & Chung-Hsing Chang. (2009) Widespread expression of prostate apoptosis response-4 in nasopharyngeal carcinoma. Head & Neck, pages NA-NA.
Crossref
Crossref
Asfar Sohail Azmi, Zhiwei Wang, Ravshan Burikhanov, Vivek M. Rangnekar, Guoping Wang, Jianyong Chen, Shaomeng Wang, Fazlul H. Sarkar & Ramzi M. Mohammad. (2008) Critical role of prostate apoptosis response-4 in determining the sensitivity of pancreatic cancer cells to small-molecule inhibitor-induced apoptosis. Molecular Cancer Therapeutics 7:9, pages 2884-2893.
Crossref
Crossref
Anindya Goswami, Shirley Qiu, Thomas S. Dexheimer, Padhma Ranganathan, Ravshan Burikhanov, Yves Pommier & Vivek M. Rangnekar. (2008) Par-4 Binds to Topoisomerase 1 and Attenuates Its DNA Relaxation Activity. Cancer Research 68:15, pages 6190-6198.
Crossref
Crossref
Tae-Jin Lee, Jung-Tae Lee, Sang Hyun Kim, Yung Hyun Choi, Kyoung Seob Song, Jong-Wook Park & Taeg Kyu Kwon. (2008) Overexpression of Par-4 enhances thapsigargin-induced apoptosis via down-regulation of XIAP and inactivation of Akt in human renal cancer cells. Journal of Cellular Biochemistry 103:2, pages 358-368.
Crossref
Crossref
Mohammed M. Shareef, Nuan Cui, Ravshan Burikhanov, Seema Gupta, Sabapathi Satishkumar, Shahin Shajahan, Mohammed Mohiuddin, Vivek M. Rangnekar & Mansoor M. Ahmed. (2007) Role of Tumor Necrosis Factor-α and TRAIL in High-Dose Radiation–Induced Bystander Signaling in Lung Adenocarcinoma. Cancer Research 67:24, pages 11811-11820.
Crossref
Crossref
Jeng-Woei Lee, Kuei-Fang Lee, Hsue-Yin Hsu, Lee-Ping Hsu, Wen-Ling Shih, Yi-Chih Chu, Wei-Ting Hsiao & Po-Fan Liu. (2007) Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines. Cancer Letters 257:2, pages 252-262.
Crossref
Crossref
Yanming Zhao, Ravshan Burikhanov, Shirley Qiu, Subodh M. Lele, C. Darrell Jennings, Subbarao Bondada, Brett Spear & Vivek M. Rangnekar. (2007) Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4. Cancer Research 67:19, pages 9276-9285.
Crossref
Crossref
Inmaculada Hernandez Gonzalez, Pino Santana, Ignacio Gonzalez-Robayna, Milagros Ferrer, Victoria Morales, Felix Lopez Blanco & Luisa F. Fanjul. (2007) Regulation of the expression of prostate apoptosis response protein 4 (Par-4) in rat granulosa cells. Apoptosis 12:4, pages 769-779.
Crossref
Crossref
Sowmyalakshmi Srinivasan, Rama S. Ranga, Ravshan Burikhanov, Seong-Su Han & Damodaran Chendil. (2007) Par-4-Dependent Apoptosis by the Dietary Compound Withaferin A in Prostate Cancer Cells. Cancer Research 67:1, pages 246-253.
Crossref
Crossref
Clark Jeffries, Diana O. Perkins & Michael Jarstfer. (2006) Systematic discovery of the grammar of translational inhibition by RNA hairpins. Journal of Theoretical Biology 241:2, pages 205-215.
Crossref
Crossref
El Bachir Affar, Margaret Po-shan Luke, Frédérique Gay, Dominica Calvo, Guangchao Sui, Robert S. Weiss, En Li & Yang Shi. (2006) Targeted Ablation of Par-4 Reveals a Cell Type–Specific Susceptibility to Apoptosis-Inducing Agents. Cancer Research 66:7, pages 3456-3462.
Crossref
Crossref
Anindya Goswami, Padhma Ranganathan & Vivek M. Rangnekar. (2006) The Phosphoinositide 3-Kinase/Akt1/Par-4 Axis: A Cancer-Selective Therapeutic Target. Cancer Research 66:6, pages 2889-2892.
Crossref
Crossref
G. Wang, J. Silva, K. Krishnamurthy & E. Bieberich. (2006) A novel isoform of prostate apoptosis response 4 (PAR-4) that co-distributes with F-actin and prevents apoptosis in neural stem cells. Apoptosis 11:3, pages 315-325.
Crossref
Crossref
Krishna Murthi Vasudevan, Padhma Ranganathan & Vivek M. Rangnekar. 2006. Regulators and Effectors of Small GTPases: Ras Family. Regulators and Effectors of Small GTPases: Ras Family
422
442
.
Meike Boosen, Susanne Vetterkind, Ansgar Koplin, Susanne Illenberger & Ute Preuss. (2005) Par-4-mediated recruitment of Amida to the actin cytoskeleton leads to the induction of apoptosis. Experimental Cell Research 311:2, pages 177-191.
Crossref
Crossref
PADHMA RANGANATHAN & VIVEK M. RANGNEKAR. (2005) Regulation of Cancer Cell Survival by Par-4. Annals of the New York Academy of Sciences 1059:1, pages 76-85.
Crossref
Crossref
Anindya Goswami, Ravshan Burikhanov, Aurelie de Thonel, Naoya Fujita, Mamta Goswami, Yanming Zhao, John E. Eriksson, Takashi Tsuruo & Vivek M. Rangnekar. (2005) Binding and Phosphorylation of Par-4 by Akt Is Essential for Cancer Cell Survival. Molecular Cell 20:1, pages 33-44.
Crossref
Crossref
Guanghu Wang, Jeane Silva, Kannan Krishnamurthy, Eric Tran, Brian G. Condie & Erhard Bieberich. (2005) Direct Binding to Ceramide Activates Protein Kinase Cζ before the Formation of a Pro-apoptotic Complex with PAR-4 in Differentiating Stem Cells. Journal of Biological Chemistry 280:28, pages 26415-26424.
Crossref
Crossref
Susanne Vetterkind, Susanne Illenberger, Jan Kubicek, Meike Boosen, Sarah Appel, Hassan Y. Naim, Karl-Heinz Scheidtmann & Ute Preuss. (2005) Binding of Par-4 to the actin cytoskeleton is essential for Par-4/Dlk-mediated apoptosis. Experimental Cell Research 305:2, pages 392-408.
Crossref
Crossref
Sushma Gurumurthy & Vivek M. Rangnekar. (2004) Par-4 inducible apoptosis in prostate cancer cells. Journal of Cellular Biochemistry 91:3, pages 504-512.
Crossref
Crossref
Qing Guo & Jun Xie. (2004) AATF Inhibits Aberrant Production of Amyloid β Peptide 1-42 by Interacting Directly with Par-4. Journal of Biological Chemistry 279:6, pages 4596-4603.
Crossref
Crossref