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Transcriptional Regulation

Regulation of Molecular Chaperone Gene Transcription Involves the Serine Phosphorylation, 14-3-3ε Binding, and Cytoplasmic Sequestration of Heat Shock Factor 1

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Pages 6013-6026 | Received 12 Dec 2002, Accepted 13 May 2003, Published online: 27 Mar 2023

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Toshiki Kijima, Thomas Prince, Len Neckers, Fumitaka Koga & Yasuhisa Fujii. (2019) Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress. Expert Opinion on Therapeutic Targets 23:5, pages 369-377.
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Marek A. Budzyński, Mikael C. Puustinen, Jenny Joutsen & Lea Sistonen. (2015) Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation. Molecular and Cellular Biology 35:14, pages 2530-2540.
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Luke Whitesell & Susan Lindquist. (2009) Inhibiting the transcription factor HSF1 as an anticancer strategy. Expert Opinion on Therapeutic Targets 13:4, pages 469-478.
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J. Tonkiss & S. K. Calderwood. (2005) Regulation of heat shock gene transcription in neuronal cells. International Journal of Hyperthermia 21:5, pages 433-444.
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Crossref
Marissa R. MartinezThiago Braido Dias, Peter S. NatovNatasha E. Zachara. (2017) Stress-induced O-GlcNAcylation: an adaptive process of injured cells. Biochemical Society Transactions 45:1, pages 237-249.
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Xu Zheng, Joanna Krakowiak, Nikit Patel, Ali Beyzavi, Jideofor Ezike, Ahmad S Khalil & David Pincus. (2016) Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation. eLife 5.
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Shardule P. Shah, Ajay K. Nooka, David L. Jaye, Nizar J. Bahlis, Sagar Lonial & Lawrence H. Boise. (2016) Bortezomib-induced heat shock response protects multiple myeloma cells and is activated by heat shock factor 1 serine 326 phosphorylation. Oncotarget 7:37, pages 59727-59741.
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Rei-Lin Kuo, Zong-Hua Li, Li-Hsin Li, Kuo-Ming Lee, Ee-Hong Tam, Helene M. Liu, Hao-Ping Liu, Shin-Ru Shih & Chih-Ching Wu. (2016) Interactome Analysis of the NS1 Protein Encoded by Influenza A H1N1 Virus Reveals a Positive Regulatory Role of Host Protein PRP19 in Viral Replication. Journal of Proteome Research 15:5, pages 1639-1648.
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Chengkai Dai & Stephen Byers Sampson. (2016) HSF1: Guardian of Proteostasis in Cancer. Trends in Cell Biology 26:1, pages 17-28.
Crossref
Shardule P. Shah, Sagar Lonial & Lawrence H. Boise. (2015) When Cancer Fights Back: Multiple Myeloma, Proteasome Inhibition, and the Heat-Shock Response. Molecular Cancer Research 13:8, pages 1163-1173.
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Yukio Ishikawa, Shotaro Kawabata & Hiroshi Sakurai. (2015) HSF1 transcriptional activity is modulated by IER5 and PP2A/B55. FEBS Letters 589:10, pages 1150-1155.
Crossref
S-D Chou, A Murshid, T Eguchi, J Gong & S K Calderwood. (2014) HSF1 regulation of β-catenin in mammary cancer cells through control of HuR/elavL1 expression. Oncogene 34:17, pages 2178-2188.
Crossref
R L Carpenter, I Paw, M W Dewhirst & H-W Lo. (2014) Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial–mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells. Oncogene 34:5, pages 546-557.
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Daeyoung Oh, Mi Ran Choi, Dal Mu Ri Han, Young Gyu Chai & Joonho Choi. (2014) Fluoxetine-induced regulation of heat shock protein 90 and 14-3-3ε in human embryonic carcinoma cells. NeuroReport 25:17, pages 1399-1404.
Crossref
Wenzhong Zhang, Fang Xu, Jingjing Han, Jun Yao, Deju Wang, Kai Yang, Ceng Zeng & Pengyuan Yang. (2014) Ferrisilicalite-1 Zeolite Monolith-Based Affinitive Recognition of Intracellular Phosphorylated Protein Alteration in Tetrahymena thermophila Exposed to Photodegradates of Roxarsone and p -Arsanilic Acid . CLEAN - Soil, Air, Water 42:12, pages 1798-1807.
Crossref
. 2014. Textbook of Neural Repair and Rehabilitation. Textbook of Neural Repair and Rehabilitation 255 328 .
Jun Zhang, Zengyi Ma, Jiyan Wang, Shulian Li, Yaqin Zhang, Yuelin Wang, Mingli Wang, Xiaoli Feng, Xiang Liu, Guangchao Liu, Qiang Lou, Xiukun Cui, Yuanfang Ma, Zheng Dong & Yan-zhong Hu. (2014) Regulation of Hsf4b nuclear translocation and transcription activity by phosphorylation at threonine 472. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1843:3, pages 580-589.
Crossref
Diana Madeira, Luís Narciso, Henrique N. Cabral, Mário S. Diniz & Catarina Vinagre. (2014) Role of thermal niche in the cellular response to thermal stress: Lipid peroxidation and HSP70 expression in coastal crabs. Ecological Indicators 36, pages 601-606.
Crossref
Tomonori Taniguchi, Shigeru Tanaka, Ayumi Ishii, Miyuki Watanabe, Noriko Fujitani, Ayusa Sugeo, Shuhei Gotoh, Takeshi Ohta, Mineyoshi Hiyoshi, Hideki Matsuzaki, Norio Sakai & Hiroaki Konishi. (2013) A Brain-specific Grb2-associated Regulator of Extracellular Signal-regulated Kinase (Erk)/Mitogen-activated Protein Kinase (MAPK) (GAREM) Subtype, GAREM2, Contributes to Neurite Outgrowth of Neuroblastoma Cells by Regulating Erk Signaling. Journal of Biological Chemistry 288:41, pages 29934-29942.
Crossref
Ioannis P. Trougakos, Fabiola Sesti, Eleni Tsakiri & Vassilis G. Gorgoulis. (2013) Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis. Journal of Proteomics 92, pages 274-298.
Crossref
Jun Zhao, Shengzhi Wang, Na Liu & Xiufa Tang. (2013) Correlation between the expression of Id-1 and hyperthermia-associated molecules in oral squamous cell carcinoma. Journal of Clinical Pathology 66:9, pages 758-763.
Crossref
Yan-Ming Xu, Dong-Yang Huang, Jen-Fu Chiu & Andy T. Y. Lau. (2012) Post-Translational Modification of Human Heat Shock Factors and Their Functions: A Recent Update by Proteomic Approach. Journal of Proteome Research 11:5, pages 2625-2634.
Crossref
Jordan Thomas Silver & Earl G. Noble. (2011) Regulation of survival gene hsp70. Cell Stress and Chaperones 17:1, pages 1-9.
Crossref
Sven-T Liffers, Abdelouahid Maghnouj, Johanna B Munding, René Jackstadt, Ulrike Herbrand, Thomas Schulenborg, Katrin Marcus, Susanne Klein-Scory, Wolff Schmiegel, Irmgard Schwarte-Waldhoff, Helmut E Meyer, Kai Stühler & Stephan A Hahn. (2011) Keratin 23, a novel DPC4/Smad4 target gene which binds 14-3-3ε. BMC Cancer 11:1.
Crossref
Julius AnckarLea Sistonen. (2011) Regulation of H SF 1 Function in the Heat Stress Response: Implications in Aging and Disease . Annual Review of Biochemistry 80:1, pages 1089-1115.
Crossref
András Orosz. 2011. Alcohol and Cancer. Alcohol and Cancer 155 173 .
Zahra Kazemi, Hana Chang, Sarah Haserodt, Cathrine McKen & Natasha E. Zachara. (2010) O-Linked β-N-acetylglucosamine (O-GlcNAc) Regulates Stress-induced Heat Shock Protein Expression in a GSK-3β-dependent Manner. Journal of Biological Chemistry 285:50, pages 39096-39107.
Crossref
Ayesha Murshid, Shiuh-Dih Chou, Thomas Prince, Yue Zhang, Ajit Bharti & Stuart K. Calderwood. (2010) Protein Kinase A Binds and Activates Heat Shock Factor 1. PLoS ONE 5:11, pages e13830.
Crossref
S. K. CalderwoodY. WangX. XieM. A KhalequeS. D ChouA. MurshidT. PrinceY. Zhang. (2010) Signal Transduction Pathways Leading to Heat Shock Transcription. Signal Transduction Insights 2, pages STI.S3994.
Crossref
Earl G. Noble, C.W. James Melling & Kevin J. Milne. 2010. Heat Shock Proteins and Whole Body Physiology. Heat Shock Proteins and Whole Body Physiology 285 316 .
Tae Gen Son, Roy G. Cutler, Mark P. Mattson & Simonetta Camandola. 2010. Hormesis. Hormesis 69 93 .
A. Graham Pockley, Stuart K. Calderwood & Gabriele Multhoff. (2009) The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions?. Cell Stress and Chaperones 14:6, pages 545-553.
Crossref
Stuart K. Calderwood, Ayesha Murshid, Bangmin Zhu & Salamatu S. Mambula. 2010. Prokaryotic and Eukaryotic Heat Shock Proteins in Infectious Disease. Prokaryotic and Eukaryotic Heat Shock Proteins in Infectious Disease 107 120 .
Earl G. NobleKevin J. MilneC.W. James Melling. (2008) Heat shock proteins and exercise: a primer. Applied Physiology, Nutrition, and Metabolism 33:5, pages 1050-1075.
Crossref
Qiang FuJunru WangMarjan BoermaMaaike BerbéeXiaohua QiuLouis M. FinkMartin Hauer-Jensen. (2008) Involvement of Heat Shock Factor 1 in Statin-Induced Transcriptional Upregulation of Endothelial Thrombomodulin. Circulation Research 103:4, pages 369-377.
Crossref
María Pilar Marín, Mónica Tomas, Guillermo Esteban-Pretel, Luis Megías, Carmen López-Iglesias, Gustavo Egea & Jaime Renau-Piqueras. (2008) Chronic ethanol exposure induces alterations in the nucleocytoplasmic transport in growing astrocytes. Journal of Neurochemistry 106:4, pages 1914-1928.
Crossref
M A Khaleque, A Bharti, J Gong, P J Gray, V Sachdev, D R Ciocca, A Stati, M Fanelli & S K Calderwood. (2007) Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1. Oncogene 27:13, pages 1886-1893.
Crossref
Stuart K. Calderwood. 2008. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection 349 364 .
Yang Shi, Craig A. Elmets, Jeffery W. Smith, Yu-Tsueng Liu, Yun-Ru Chen, Cheng-Po Huang, Wenhong Zhu, Honnavara N. Ananthaswamy, Richard L. Gallo & Chun-Ming Huang. (2007) Quantitative proteomes andin vivo secretomes of progressive and regressive UV-induced fibrosarcoma tumor cells: Mimicking tumor microenvironment using a dermis-based cell-trapped system linked to tissue chamber. PROTEOMICS 7:24, pages 4589-4600.
Crossref
László Vigh, Ibolya Horváth, Bruno Maresca & John L. Harwood. (2007) Can the stress protein response be controlled by ‘membrane-lipid therapy’?. Trends in Biochemical Sciences 32:8, pages 357-363.
Crossref
Srinivas S. Gampala, Tae-Wuk Kim, Jun-Xian He, Wenqiang Tang, Zhiping Deng, Mingyi-Yi Bai, Shenheng Guan, Sylvie Lalonde, Ying Sun, Joshua M. Gendron, Huanjing Chen, Nakako Shibagaki, Robert J. Ferl, David Ehrhardt, Kang Chong, Alma L. Burlingame & Zhi-Yong Wang. (2007) An Essential Role for 14-3-3 Proteins in Brassinosteroid Signal Transduction in Arabidopsis. Developmental Cell 13:2, pages 177-189.
Crossref
Ivan S. Chernik, Alim S. Seit-Nebi, Steven B. Marston & Nikolai B. Gusev. (2006) Small heat shock protein Hsp20 (HspB6) as a partner of 14-3-3γ. Molecular and Cellular Biochemistry 295:1-2, pages 9-17.
Crossref
Stuart K. Calderwood, Md Abdul Khaleque, Ajit Bharti & Daniel R. Ciocca. 2007. Heat Shock Proteins in Cancer. Heat Shock Proteins in Cancer 53 72 .
Stuart K Calderwood, Xianzhong Xiao & Yue Xie. 2007. Heat Shock Proteins: Potent Mediators of Inflammation and Immunity. Heat Shock Proteins: Potent Mediators of Inflammation and Immunity 95 113 .
Julius Anckar & Lea Sistonen. 2007. Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks. Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks 78 88 .
Sébastien Ian Nadeau & Jacques Landry. 2007. Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks. Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks 100 113 .
Richard Voellmy. 2007. Cell Stress Proteins. Cell Stress Proteins 122 139 .
Haeng Ran Seo, Da-Yeon Chung, Yoon-Jin Lee, Dae-Hoon Lee, Jong-Il Kim, Sangwoo Bae, Hee-Yong Chung, Su-Jae Lee, Dooil Jeoung & Yun-Sil Lee. (2006) Heat Shock Protein 25 or Inducible Heat Shock Protein 70 Activates Heat Shock Factor 1. Journal of Biological Chemistry 281:25, pages 17220-17227.
Crossref
John M. Lawler, Wook Song & Hyo-Bum Kwak. (2006) Differential response of heat shock proteins to hindlimb unloading and reloading in the soleus. Muscle & Nerve 33:2, pages 200-207.
Crossref
XiaoZhe Wang, Md Abdul Khaleque, Mei Juan Zhao, Rong Zhong, Matthias Gaestel & Stuart K. Calderwood. (2006) Phosphorylation of HSF1 by MAPK-Activated Protein Kinase 2 on Serine 121, Inhibits Transcriptional Activity and Promotes HSP90 Binding. Journal of Biological Chemistry 281:2, pages 782-791.
Crossref
Ville Hietakangas & Lea Sistonen. 2006. Chaperones. Chaperones 1 34 .
R. Voellmy. 2006. Molecular Chaperones in Health and Disease. Molecular Chaperones in Health and Disease 43 68 .
Csaba Sõti, Enikõ Nagy, Zoltán Giricz, László Vígh, Péter Csermely & Péter Ferdinandy. (2005) Heat shock proteins as emerging therapeutic targets. British Journal of Pharmacology 146:6, pages 769-780.
Crossref
Md Abdul Khaleque, Ajit Bharti, Douglas Sawyer, Jianlin Gong, Ivor J Benjamin, Mary Ann Stevenson & Stuart K Calderwood. (2005) Induction of heat shock proteins by heregulin β1 leads to protection from apoptosis and anchorage-independent growth. Oncogene 24:43, pages 6564-6573.
Crossref
Woei-Cherng Shyu, Shinn-Zong Lin, Ming-Fu Chiang, Dah-Ching Ding, Kuo-Wei Li, Shih-Fen Chen, Hui-I Yang & Hung Li. (2005) Overexpression of PrP C by Adenovirus-Mediated Gene Targeting Reduces Ischemic Injury in a Stroke Rat Model . The Journal of Neuroscience 25:39, pages 8967-8977.
Crossref
Alexzander Asea & Stuart K. Calderwood. 2009. Molecular Chaperones and Cell Signalling. Molecular Chaperones and Cell Signalling 133 143 .
XiaoZhe Wang, Nicholas Grammatikakis, Aliki Siganou, Mary Ann Stevenson & Stuart K. Calderwood. (2004) Interactions between Extracellular Signal-regulated Protein Kinase 1, 14-3-3ϵ, and Heat Shock Factor 1 during Stress. Journal of Biological Chemistry 279:47, pages 49460-49469.
Crossref
Stuart Thomson, Angela Hollis, Catherine A. Hazzalin & Louis C. Mahadevan. (2004) Distinct Stimulus-Specific Histone Modifications at Hsp70 Chromatin Targeted by the Transcription Factor Heat Shock Factor-1. Molecular Cell 15:4, pages 585-594.
Crossref
Jun-ichi Satoh, Takashi Yamamura & Kunimasa Arima. (2004) The 14-3-3 Protein ε Isoform Expressed in Reactive Astrocytes in Demyelinating Lesions of Multiple Sclerosis Binds to Vimentin and Glial Fibrillary Acidic Protein in Cultured Human Astrocytes. The American Journal of Pathology 165:2, pages 577-592.
Crossref
Yiqun Wang, Jimmy R. Theriault, Haiying He, Jianlin Gong & Stuart K. Calderwood. (2004) Expression of a Dominant Negative Heat Shock Factor-1 Construct Inhibits Aneuploidy in Prostate Carcinoma Cells*. Journal of Biological Chemistry 279:31, pages 32651-32659.
Crossref
Donald B. DeFranco, Louisa Ho, Eric Falke & Clifton W. Callaway. (2004) Small molecule activators of the heat shock response and neuroprotection from stroke. Current Atherosclerosis Reports 6:4, pages 295-300.
Crossref
Guanghu Wang, Zhekang Ying, Xiongjie Jin, Naxin Tu, Yan Zhang, Michele Phillips, Demetrius Moskophidis & Nahid F. Mivechi. (2004) Essential requirement for bothhsf1 andhsf2 transcriptional activity in spermatogenesis and male fertility. genesis 38:2, pages 66-80.
Crossref

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