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Molecular and Cellular Biology Volume 23, 2003 - Issue 19
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Transcriptional Regulation

Repression of the Luteinizing Hormone Receptor Gene Promoter by Cross Talk among EAR3/COUP-TFI, Sp1/Sp3, and TFIIB

Ying ZhangSection on Molecular Endocrinology, Endocrinology, and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland20892
&
Maria L. DufauSection on Molecular Endocrinology, Endocrinology, and Reproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland20892Correspondence[email protected]
Pages 6958-6972 | Received 10 Feb 2003, Accepted 30 Jun 2003, Published online: 27 Mar 2023

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Ying Zhang, Mingjuan Liao & Maria L. Dufau. (2006) Phosphatidylinositol 3-Kinase/Protein Kinase Cζ-Induced Phosphorylation of Sp1 and p107 Repressor Release Have a Critical Role in Histone Deacetylase Inhibitor-Mediated Depression of Transcription of the Luteinizing Hormone Receptor Gene. Molecular and Cellular Biology 26:18, pages 6748-6761.
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Ying Zhang, Naheed Fatima & Maria L. Dufau. (2005) Coordinated Changes in DNA Methylation and Histone Modifications Regulate Silencing/Derepression of Luteinizing Hormone Receptor Gene Transcription. Molecular and Cellular Biology 25:18, pages 7929-7939.
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Articles from other publishers (33)

Ying Zhang, Yi Xiang See, Vinay Tergaonkar & Melissa Jane Fullwood. (2022) Long-Distance Repression by Human Silencers: Chromatin Interactions and Phase Separation in Silencers. Cells 11:9, pages 1560.
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Kyungsil Yoon, Chien-Cheng Chen, Asuka Orr, Patricia Barreto, Phanourios Tamamis & Stephen Safe. (2019) Activation of COUP-TFI by a Novel Diindolylmethane Derivative. Cells 8:3, pages 220.
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Prema Narayan, Alfredo Ulloa-Aguirre & James A. Dias. 2019. Yen and Jaffe's Reproductive Endocrinology. Yen and Jaffe's Reproductive Endocrinology 25 57.e15 .
Ruipeng Lu, Eliseos J. Mucaki & Peter K. Rogan. (2017) Discovery and validation of information theory-based transcription factor and cofactor binding site motifs. Nucleic Acids Research 45:5, pages e27-e27.
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Alexandra Lacey, Erik Hedrick, Xi Li, Ketan Patel, Ravi Doddapaneni, Mandip Singh & Stephen Safe. (2016) Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS). Oncotarget 7:21, pages 31257-31269.
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Tomoko Kawai, Noriyuki Yanaka, JoAnne S. Richards & Masayuki Shimada. (2016) De Novo-Synthesized Retinoic Acid in Ovarian Antral Follicles Enhances FSH-Mediated Ovarian Follicular Cell Differentiation and Female Fertility. Endocrinology 157:5, pages 2160-2172.
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Catherine M. Syddall, Louise N. Reynard, David A. Young & John Loughlin. (2013) The Identification of Trans-acting Factors That Regulate the Expression of GDF5 via the Osteoarthritis Susceptibility SNP rs143383. PLoS Genetics 9:6, pages e1003557.
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Weiguo Xu, Qi Zhu, Zhenghua Wu, Hao Guo, Fengjuan Wu, Dhahiri S. Mashausi, Chengjie Zheng & Dawei Li. (2012) A Novel Evolutionarily Conserved Element Is a General Transcriptional Repressor of p21WAF1/CIP1. Cancer Research 72:23, pages 6236-6246.
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Hwa Jin Lee, Brian A. Wall, Janet Wangari-Talbot & Suzie Chen. (2012) Regulation of mGluR1 expression in human melanocytes and melanoma cells. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1819:11-12, pages 1123-1131.
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Sander van den Driesche, Marion Walker, Chris McKinnell, Hayley M. Scott, Sharon L. Eddie, Rod T. Mitchell, Jonathan R. Seckl, Amanda J. Drake, Lee B. Smith, Richard A. Anderson & Richard M. Sharpe. (2012) Proposed Role for COUP-TFII in Regulating Fetal Leydig Cell Steroidogenesis, Perturbation of Which Leads to Masculinization Disorders in Rodents. PLoS ONE 7:5, pages e37064.
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S. V. Razin, V. V. Borunova, O. G. Maksimenko & O. L. Kantidze. (2012) Cys2His2 zinc finger protein family: Classification, functions, and major members. Biochemistry (Moscow) 77:3, pages 217-226.
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Mingjuan Liao, Ying Zhang, Jung-Hoon Kang & Maria L. Dufau. (2011) Coactivator Function of Positive Cofactor 4 (PC4) in Sp1-directed Luteinizing Hormone Receptor (LHR) Gene Transcription. Journal of Biological Chemistry 286:9, pages 7681-7691.
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Lisa M. Crowther, Shu-Ching Mary Wang, Natalie A. Eriksson, Stephen A. Myers, Lauren A. Murray & George E. O. Muscat. (2011) Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells. Physiological Genomics 43:4, pages 213-227.
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Magdalena Karolczak-Bayatti, Andrew D. Loughney, Stephen C. Robson & G. Nicholas Europe-Finner. (2011) Epigenetic modulation of the protein kinase A RIIα (PRKAR2A) gene by histone deacetylases 1 and 2 in human smooth muscle cells. Journal of Cellular and Molecular Medicine 15:1, pages 94-108.
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Weiming Zheng, Cheryl D. Horton, Jonathan Kim & Lisa M. Halvorson. (2010) The orphan nuclear receptors COUP-TFI and COUP-TFII regulate expression of the gonadotropin LHβ gene. Molecular and Cellular Endocrinology 330:1-2, pages 59-71.
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Lin Li & James R. Davie. (2010) The role of Sp1 and Sp3 in normal and cancer cell biology. Annals of Anatomy - Anatomischer Anzeiger 192:5, pages 275-283.
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Laura K. Cole & Dennis E. Vance. (2010) A Role for Sp1 in Transcriptional Regulation of Phosphatidylethanolamine N-Methyltransferase in Liver and 3T3-L1 Adipocytes. Journal of Biological Chemistry 285:16, pages 11880-11891.
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Maria L. Dufau, Mingjuan Liao & Ying Zhang. (2010) Participation of signaling pathways in the derepression of luteinizing hormone receptor transcription. Molecular and Cellular Endocrinology 314:2, pages 221-227.
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Ling-juan Zhang, Xiao Liu, Philip R. Gafken, Chrissa Kioussi & Mark Leid. (2009) A Chicken Ovalbumin Upstream Promoter Transcription Factor I (COUP-TFI) Complex Represses Expression of the Gene Encoding Tumor Necrosis Factor α-induced Protein 8 (TNFAIP8). Journal of Biological Chemistry 284:10, pages 6156-6168.
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Elizebeth C. Turner & B. Therese Kinsella. (2009) Transcriptional Regulation of the Human Prostacyclin Receptor Gene Is Dependent on Sp1, PU.1 and Oct-1 in Megakaryocytes and Endothelial Cells. Journal of Molecular Biology 386:3, pages 579-597.
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Michael W.Y. Chan, Yi-Wen Huang, Corinna Hartman-Frey, Chieh-Ti Kuo, Daniel Deatherage, Huaxia Qin, Alfred S.L. Cheng, Pearlly S. Yan, Ramana V. Davuluri, Tim H.-M. Huang, Kenneth P. Nephew & Huey-Jen L. Lin. (2008) Aberrant Transforming Growth Factor β1 Signaling and SMAD4 Nuclear Translocation Confer Epigenetic Repression of ADAM19 in Ovarian Cancer. Neoplasia 10:9, pages 908-IN2.
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Ying Zhang, Mingjuan Liao & Maria L. Dufau. (2008) Unlocking Repression of the Human Luteinizing Hormone Receptor Gene by Trichostatin A-induced Cell-specific Phosphatase Release. Journal of Biological Chemistry 283:35, pages 24039-24046.
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Inken Wierstra. (2008) Sp1: Emerging roles—Beyond constitutive activation of TATA-less housekeeping genes. Biochemical and Biophysical Research Communications 372:1, pages 1-13.
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Mingjuan Liao, Ying Zhang & Maria L. Dufau. (2008) Protein Kinase Cα-Induced Derepression of the Human Luteinizing Hormone Receptor Gene Transcription through ERK-Mediated Release of HDAC1/Sin3A Repressor Complex from Sp1 Sites. Molecular Endocrinology 22:6, pages 1449-1463.
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James R. Davie, Shihua He, Lin Li, Anoushe Sekhavat, Paula Espino, Bojan Drobic, Katherine L. Dunn, Jian-Min Sun, Hou Yu Chen, Jenny Yu, Susan Pritchard & Xuemei Wang. (2008) Nuclear organization and chromatin dynamics – Sp1, Sp3 and histone deacetylases. Advances in Enzyme Regulation 48:1, pages 189-208.
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Maria L. Dufau & Chon-Hwa Tsai-Morris. 2007. The Leydig Cell in Health and Disease. The Leydig Cell in Health and Disease 227 252 .
Chun Sung Kim, Hack Sun Choi, Cheol Kyu Hwang, Kyu Young Song, Byung-Kwon Lee, Ping-Yee Law, Li-Na Wei & Horace H. Loh. (2006) Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene. Nucleic Acids Research 34:22, pages 6392-6403.
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Juying Dong, Chon-Hwa Tsai-Morris & Maria L. Dufau. (2006) A Novel Estradiol/Estrogen Receptor α-dependent Transcriptional Mechanism Controls Expression of the Human Prolactin Receptor. Journal of Biological Chemistry 281:27, pages 18825-18836.
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Aida Rivera-Gines, Ryan J. Cook, Horace H. Loh & Jane L. Ko. (2006) Interplay of Sps and poly(C) binding protein 1 on the μ-opioid receptor gene expression. Biochemical and Biophysical Research Communications 345:1, pages 530-537.
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Achim Ehrnsperger, Michael Rehli, Pham Thu-Hang & Marina Kreutz. (2005) Epigenetic regulation of the dendritic cell-marker gene ADAM19. Biochemical and Biophysical Research Communications 332:2, pages 456-464.
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Steven A. Innocente & Jonathan M. Lee. (2005) p53 is a NF-Y- and p21-independent, Sp1-dependent repressor of cyclin B1 transcription. FEBS Letters 579:5, pages 1001-1007.
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Lin Li, Shihua He, Jian-Min Sun & James R Davie. (2004) Gene regulation by Sp1 and Sp3. Biochemistry and Cell Biology 82:4, pages 460-471.
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Ying Zhang & Maria L Dufau. 2004. Nuclear Receptor Coregulators. Nuclear Receptor Coregulators 1 48 .

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