Molecular and Cellular Biology, Volume 23, Issue 19 (2003)

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Molecular and Cellular Biology, Volume 23, Issue 19 (2003)

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Transcriptional Regulation

Article
Pancreatic-Duodenal Homeobox 1 Regulates Expression of Liver Receptor Homolog 1 during Pancreas Development
Jean-Sébastien Annicotte, Elisabeth Fayard, Galvin H. Swift, Lars Selander, Helena Edlund, Toshiya Tanaka, Tatsuhiko Kodama, Kristina Schoonjans & Johan Auwerx
Pages: 6713-6724
Published online: 27 Mar 2023
AbstractforPancreatic-Duodenal Homeobox 1 Regulates Expression of Liver Receptor Homolog 1 during Pancreas Development | Full Text | References | PDF (976.4 KB)
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Article
A Dominant-Negative Thyroid Hormone Receptor Blocks Amphibian Metamorphosis by Retaining Corepressors at Target Genes
Daniel R. Buchholz, Shao-Chung Victor Hsia, Liezhen Fu & Yun-Bo Shi
Pages: 6750-6758
Published online: 27 Mar 2023
AbstractforA Dominant-Negative Thyroid Hormone Receptor Blocks Amphibian Metamorphosis by Retaining Corepressors at Target Genes | Full Text | References | PDF (510.5 KB)
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Article
Cdk7 Is Required for Full Activation of Drosophila Heat Shock Genes and RNA Polymerase II Phosphorylation In Vivo
Brian E. Schwartz, Stephane Larochelle, Beat Suter & John T. Lis
Pages: 6876-6886
Published online: 27 Mar 2023
AbstractforCdk7 Is Required for Full Activation of Drosophila Heat Shock Genes and RNA Polymerase II Phosphorylation In Vivo | Full Text | References | PDF (872.3 KB)
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Article
Estrogen Withdrawal-Induced NF-κB Activity and Bcl-3 Expression in Breast Cancer Cells: Roles in Growth and Hormone Independence
M. A. Christine Pratt, Tanya E. Bishop, Dawn White, Gordon Yasvinski, Michel Ménard, Min Ying Niu & Robert Clarke
Pages: 6887-6900
Published online: 27 Mar 2023
AbstractforEstrogen Withdrawal-Induced NF-κB Activity and Bcl-3 Expression in Breast Cancer Cells: Roles in Growth and Hormone Independence | Full Text | References | PDF (498.9 KB)
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Article
A Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription
Nickolai A. Barlev, Alexander V. Emelyanov, Paola Castagnino, Philip Zegerman, Andrew J. Bannister, Manuel A. Sepulveda, Flavie Robert, Laszlo Tora, Tony Kouzarides, Barbara K. Birshtein & Shelley L. Berger
Pages: 6944-6957
Published online: 27 Mar 2023
AbstractforA Novel Human Ada2 Homologue Functions with Gcn5 or Brg1 To Coactivate Transcription | Full Text | References | PDF (689.6 KB)
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Article
Repression of the Luteinizing Hormone Receptor Gene Promoter by Cross Talk among EAR3/COUP-TFI, Sp1/Sp3, and TFIIB
Ying Zhang & Maria L. Dufau
Pages: 6958-6972
Published online: 27 Mar 2023
AbstractforRepression of the Luteinizing Hormone Receptor Gene Promoter by Cross Talk among EAR3/COUP-TFI, Sp1/Sp3, and TFIIB | Full Text | References | PDF (481.3 KB)
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Article
A Phosphomimetic Mutation at Ser-138 Renders Iron Regulatory Protein 1 Sensitive to Iron-Dependent Degradation
Carine Fillebeen, Danielle Chahine, Annie Caltagirone, Phillip Segal & Kostas Pantopoulos
Pages: 6973-6981
Published online: 27 Mar 2023
AbstractforA Phosphomimetic Mutation at Ser-138 Renders Iron Regulatory Protein 1 Sensitive to Iron-Dependent Degradation | Full Text | References | PDF (479.7 KB)
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Article
Bur1 Kinase Is Required for Efficient Transcription Elongation by RNA Polymerase II
Michael-Christopher Keogh, Vladimir Podolny & Stephen Buratowski
Pages: 7005-7018
Published online: 27 Mar 2023
AbstractforBur1 Kinase Is Required for Efficient Transcription Elongation by RNA Polymerase II | Full Text | References | PDF (786.4 KB)
  • 45 Views
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Article
Purification and Identification of a Novel Complex Which Is Involved in Androgen Receptor-Dependent Transcription
Keiko Hosohata, Peng Li, Yoshiaki Hosohata, Jun Qin, Robert G. Roeder & Zhengxin Wang
Pages: 7019-7029
Published online: 27 Mar 2023
AbstractforPurification and Identification of a Novel Complex Which Is Involved in Androgen Receptor-Dependent Transcription | Full Text | References | PDF (519.3 KB)
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Cell Growth and Development

Article
Role of Metalloprotease Disintegrin ADAM12 in Determination of Quiescent Reserve Cells during Myogenic Differentiation In Vitro
Yi Cao, Zhefeng Zhao, Joanna Gruszczynska-Biegala & Anna Zolkiewska
Pages: 6725-6738
Published online: 27 Mar 2023
AbstractforRole of Metalloprotease Disintegrin ADAM12 in Determination of Quiescent Reserve Cells during Myogenic Differentiation In Vitro | Full Text | References | PDF (966.5 KB)
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Article
Defective Brain Development in Mice Lacking the Hif-1α Gene in Neural Cells
Shuhei Tomita, Masaki Ueno, Masami Sakamoto, Yuki Kitahama, Masaaki Ueki, Nobuhiro Maekawa, Haruhiko Sakamoto, Max Gassmann, Ryoichiro Kageyama, Natsuo Ueda, Frank J. Gonzalez & Yousuke Takahama
Pages: 6739-6749
Published online: 27 Mar 2023
AbstractforDefective Brain Development in Mice Lacking the Hif-1α Gene in Neural Cells | Full Text | References | PDF (1.5 MB)
  • 107 Views
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Article
Actin Can Reorganize into Podosomes in Aortic Endothelial Cells, a Process Controlled by Cdc42 and RhoA
Violaine Moreau, Florence Tatin, Christine Varon & Elisabeth Génot
Pages: 6809-6822
Published online: 27 Mar 2023
AbstractforActin Can Reorganize into Podosomes in Aortic Endothelial Cells, a Process Controlled by Cdc42 and RhoA | Full Text | References | PDF (2.3 MB)
  • 36 Views
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Article
Functional Analysis of the Caenorhabditis elegans UNC-73B PH Domain Demonstrates a Role in Activation of the Rac GTPase In Vitro and Axon Guidance In Vivo
Terrance J. Kubiseski, Joe Culotti & Tony Pawson
Pages: 6823-6835
Published online: 27 Mar 2023
AbstractforFunctional Analysis of the Caenorhabditis elegans UNC-73B PH Domain Demonstrates a Role in Activation of the Rac GTPase In Vitro and Axon Guidance In Vivo | Full Text | References | PDF (904.9 KB)
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Article
Regulation of the Activity of p38 Mitogen-Activated Protein Kinase by Akt in Cancer and Adenoviral Protein E1A-Mediated Sensitization to Apoptosis
Yong Liao & Mien-Chie Hung
Pages: 6836-6848
Published online: 27 Mar 2023
AbstractforRegulation of the Activity of p38 Mitogen-Activated Protein Kinase by Akt in Cancer and Adenoviral Protein E1A-Mediated Sensitization to Apoptosis | Full Text | References | PDF (815.8 KB)
  • 19 Views
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Article
Functions of the Ectodomain and Cytoplasmic Tyrosine Phosphatase Domains of Receptor Protein Tyrosine Phosphatase Dlar In Vivo
Neil X. Krueger, R. Sreekantha Reddy, Karl Johnson, Jack Bateman, Nancy Kaufmann, Daniella Scalice, David Van Vactor & Haruo Saito
Pages: 6909-6921
Published online: 27 Mar 2023
AbstractforFunctions of the Ectodomain and Cytoplasmic Tyrosine Phosphatase Domains of Receptor Protein Tyrosine Phosphatase Dlar In Vivo | Full Text | References | PDF (663.3 KB)
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Article
Phosphorylation of the Carboxyl-Terminal Transactivation Domain of c-Fos by Extracellular Signal-Regulated Kinase Mediates the Transcriptional Activation of AP-1 and Cellular Transformation Induced by Platelet-Derived Growth Factor
Paula Monje, Maria Julia Marinissen & J. Silvio Gutkind
Pages: 7030-7043
Published online: 27 Mar 2023
AbstractforPhosphorylation of the Carboxyl-Terminal Transactivation Domain of c-Fos by Extracellular Signal-Regulated Kinase Mediates the Transcriptional Activation of AP-1 and Cellular Transformation Induced by Platelet-Derived Growth Factor | Full Text | References | PDF (660.7 KB)
  • 38 Views
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Article
NAD+-Dependent Deacetylase Hst1p Controls Biosynthesis and Cellular NAD+ Levels in Saccharomyces cerevisiae
Antonio Bedalov, Maki Hirao, Jeffrey Posakony, Melisa Nelson & Julian A. Simon
Pages: 7044-7054
Published online: 27 Mar 2023
AbstractforNAD+-Dependent Deacetylase Hst1p Controls Biosynthesis and Cellular NAD+ Levels in Saccharomyces cerevisiae | Full Text | References | PDF (475.9 KB)
  • 154 Views
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Dna Dynamics and Chromosome Structure

Article
Functional Analysis of the Subunits of the Chromatin Assembly Factor RSF
Alejandra Loyola, Jing-Yi Huang, Gary LeRoy, Sherrie Hu, Yuh-Hwa Wang, Robert J. Donnelly, William S. Lane, Sheng-Chung Lee & Danny Reinberg
Pages: 6759-6768
Published online: 27 Mar 2023
AbstractforFunctional Analysis of the Subunits of the Chromatin Assembly Factor RSF | Full Text | References | PDF (639.5 KB)
  • 88 Views
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Article
CpG Methylation of DNA Restricts Prereplication Complex Assembly in Xenopus Egg Extracts
Kevin J. Harvey & John Newport
Pages: 6769-6779
Published online: 27 Mar 2023
AbstractforCpG Methylation of DNA Restricts Prereplication Complex Assembly in Xenopus Egg Extracts | Full Text | References | PDF (541.3 KB)
  • 12 Views
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Article
Comprehensive Structure-Function Analysis of the Core Domain of Human Telomerase RNA
Hinh Ly, Elizabeth H. Blackburn & Tristram G. Parslow
Pages: 6849-6856
Published online: 27 Mar 2023
AbstractforComprehensive Structure-Function Analysis of the Core Domain of Human Telomerase RNA | Full Text | References | PDF (453.3 KB)
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Targeted Disruption of the Mouse PAS Domain Serine/Threonine Kinase PASKIN
Dürthe M. Katschinski, Hugo H. Marti, Klaus F. Wagner, Junpei Shibata, Katrin Eckhardt, Falk Martin, Reinhard Depping, Uwe Paasch, Max Gassmann, Birgit Ledermann, Isabelle Desbaillets & Roland H. Wenger
Pages: 6780-6789
Published online: 27 Mar 2023
AbstractforTargeted Disruption of the Mouse PAS Domain Serine/Threonine Kinase PASKIN | Full Text | References | PDF (903.6 KB)
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Article
Disruption of the COP9 Signalosome Csn2 Subunit in Mice Causes Deficient Cell Proliferation, Accumulation of p53 and Cyclin E, and Early Embryonic Death
Karin Lykke-Andersen, Laura Schaefer, Suchithra Menon, Xing-Wang Deng, Jeffrey Boone Miller & Ning Wei
Pages: 6790-6797
Published online: 27 Mar 2023
AbstractforDisruption of the COP9 Signalosome Csn2 Subunit in Mice Causes Deficient Cell Proliferation, Accumulation of p53 and Cyclin E, and Early Embryonic Death | Full Text | References | PDF (641.9 KB)
  • 38 Views
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Article
COP9 Signalosome Subunit 3 Is Essential for Maintenance of Cell Proliferation in the Mouse Embryonic Epiblast
Jiong Yan, Katherina Walz, Hisashi Nakamura, Sandra Carattini-Rivera, Qi Zhao, Hannes Vogel, Ning Wei, Monica J. Justice, Allan Bradley & James R. Lupski
Pages: 6798-6808
Published online: 27 Mar 2023
AbstractforCOP9 Signalosome Subunit 3 Is Essential for Maintenance of Cell Proliferation in the Mouse Embryonic Epiblast | Full Text | References | PDF (1 MB)
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Article
Purα Is Essential for Postnatal Brain Development and Developmentally Coupled Cellular Proliferation As Revealed by Genetic Inactivation in the Mouse
Kamel Khalili, Luis Del Valle, Vandhana Muralidharan, William J. Gault, Nune Darbinian, Jessica Otte, Ellen Meier, Edward M. Johnson, Dianne C. Daniel, Yayoi Kinoshita, Shohreh Amini & Jennifer Gordon
Pages: 6857-6875
Published online: 27 Mar 2023
AbstractforPurα Is Essential for Postnatal Brain Development and Developmentally Coupled Cellular Proliferation As Revealed by Genetic Inactivation in the Mouse | Full Text | References | PDF (2.8 MB)
  • 87 Views
  • 132 CrossRef citations
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Article
Role of Plk2 (Snk) in Mouse Development and Cell Proliferation
Sheng Ma, Jean Charron & Raymond L. Erikson
Pages: 6936-6943
Published online: 27 Mar 2023
AbstractforRole of Plk2 (Snk) in Mouse Development and Cell Proliferation | Full Text | References | PDF (376.4 KB)
  • 65 Views
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Gene Expression

Article
EBNA-1, a Bifunctional Transcriptional Activator
Gregory Kennedy & Bill Sugden
Pages: 6901-6908
Published online: 27 Mar 2023
AbstractforEBNA-1, a Bifunctional Transcriptional Activator | Full Text | References | PDF (265.7 KB)
  • 30 Views
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Article
Hes6 Promotes Cortical Neurogenesis and Inhibits Hes1 Transcription Repression Activity by Multiple Mechanisms
Michel-Olivier Gratton, Elena Torban, Stephanie Belanger Jasmin, Francesca M. Theriault, Michael S. German & Stefano Stifani
Pages: 6922-6935
Published online: 27 Mar 2023
AbstractforHes6 Promotes Cortical Neurogenesis and Inhibits Hes1 Transcription Repression Activity by Multiple Mechanisms | Full Text | References | PDF (491 KB)
  • 62 Views
  • 88 CrossRef citations
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Article
Rrp47p Is an Exosome-Associated Protein Required for the 3′ Processing of Stable RNAs
Philip Mitchell, Elisabeth Petfalski, Rym Houalla, Alexandre Podtelejnikov, Matthias Mann & David Tollervey
Pages: 6982-6992
Published online: 27 Mar 2023
AbstractforRrp47p Is an Exosome-Associated Protein Required for the 3′ Processing of Stable RNAs | Full Text | References | PDF (526.5 KB)
  • 34 Views
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Article
Autoregulation of Mouse Histone Deacetylase 1 Expression
Bernd Schuettengruber, Elisabeth Simboeck, Harald Khier & Christian Seiser
Pages: 6993-7004
Published online: 27 Mar 2023
AbstractforAutoregulation of Mouse Histone Deacetylase 1 Expression | Full Text | References | PDF (580.8 KB)
  • 11 Views
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Article
Identification of mRNAs Associated with αCP2-Containing RNP Complexes
Shelly A. Waggoner & Stephen A. Liebhaber
Pages: 7055-7067
Published online: 27 Mar 2023
AbstractforIdentification of mRNAs Associated with αCP2-Containing RNP Complexes | Full Text | References | PDF (335.1 KB)
  • 11 Views
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Article
Protein Kinase Cα (PKCα) Acts Upstream of PKCθ To Activate IκB Kinase and NF-κB in T Lymphocytes
Sergey A. Trushin, Kevin N. Pennington, Eva M. Carmona, Susana Asin, Doris N. Savoy, Daniel D. Billadeau & Carlos V. Paya
Pages: 7068-7081
Published online: 27 Mar 2023
AbstractforProtein Kinase Cα (PKCα) Acts Upstream of PKCθ To Activate IκB Kinase and NF-κB in T Lymphocytes | Full Text | References | PDF (525.5 KB)
  • 26 Views
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