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Mammalian Genetic Models with Minimal or Complex Phenotypes

Disruption of the Regulatory β Subunit of Protein Kinase CK2 in Mice Leads to a Cell-Autonomous Defect and Early Embryonic Lethality

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Pages 908-915 | Received 05 Aug 2002, Accepted 07 Nov 2002, Published online: 27 Mar 2023

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Christian Borgo, Claudio D’Amore, Luca Cesaro, Stefania Sarno, Lorenzo A. Pinna, Maria Ruzzene & Mauro Salvi. (2021) How can a traffic light properly work if it is always green? The paradox of CK2 signaling. Critical Reviews in Biochemistry and Molecular Biology 56:4, pages 321-359.
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Qianwen Li, Ke Li, Sheng Zhang, Yu Zhou, Jiaxin Hong, Xiaoshu Zhou, Zhenyu Li, Bian Wu, Gang Wu & Rui Meng. (2019) The effect of ionizing radiation on the subcellular localization and kinase activity of protein kinase CK2 in human non-small cell lung cancer cells. International Journal of Radiation Biology 95:11, pages 1462-1471.
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Emmanuel Ampofo, Beate M. Schmitt, Matthias W. Laschke & Michael D. Menger. (2019) Function of protein kinase CK2 in thrombus formation. Platelets 30:4, pages 421-427.
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Emmanuelle Huillard, Léa Ziercher, Olivier Blond, Michael Wong, Jean-Christophe Deloulme, Serhiy Souchelnytskyi, Jacques Baudier, Claude Cochet & Thierry Buchou. (2010) Disruption of CK2β in Embryonic Neural Stem Cells Compromises Proliferation and Oligodendrogenesis in the Mouse Telencephalon. Molecular and Cellular Biology 30:11, pages 2737-2749.
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David Y. Lou, Isabel Dominguez, Paul Toselli, Esther Landesman-Bollag, Conor O'Brien & David C. Seldin. (2008) The Alpha Catalytic Subunit of Protein Kinase CK2 Is Required for Mouse Embryonic Development. Molecular and Cellular Biology 28:1, pages 131-139.
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Elena I. Schwartz, Robert V. Intine & Richard J. Maraia. (2004) CK2 Is Responsible for Phosphorylation of Human La Protein Serine-366 and Can Modulate rpL37 5′-Terminal Oligopyrimidine mRNA Metabolism. Molecular and Cellular Biology 24:21, pages 9580-9591.
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Hugh N. Nuthall, Kerline Joachim & Stefano Stifani. (2004) Phosphorylation of Serine 239 of Groucho/TLE1 by Protein Kinase CK2 Is Important for Inhibition of Neuronal Differentiation. Molecular and Cellular Biology 24:19, pages 8395-8407.
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