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Molecular and Cellular Biology Volume 23, 2003 - Issue 7
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Transcriptional Regulation

Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast Carcinoma

Gustavo Baldassarre1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107
,
Sabrina Battista1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107;2 Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli “Federico II,” 80131Naples, Italy
,
Barbara Belletti1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107
,
Sanjay Thakur1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107
,
Francesca Pentimalli1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107;2 Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli “Federico II,” 80131Naples, Italy
,
Francesco Trapasso1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107
,
Monica Fedele2 Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli “Federico II,” 80131Naples, Italy
,
Giovanna Pierantoni2 Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli “Federico II,” 80131Naples, Italy
,
Carlo M. Croce1 Kimmel Cancer Center, Jefferson Medical College, Philadelphia, Pennsylvania19107
&
Alfredo Fusco2 Dipartimento di Biologia e Patologia Cellulare e Molecolare c/o Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli “Federico II,” 80131Naples, ItalyCorrespondence[email protected]
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Pages 2225-2238 | Received 16 Sep 2002, Accepted 26 Dec 2002, Published online: 27 Mar 2023

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Silvia Pegoraro, Gloria Ros, Michela Sgubin, Sara Petrosino, Alberto Zambelli, Riccardo Sgarra & Guidalberto Manfioletti. (2020) Targeting the intrinsically disordered architectural High Mobility Group A (HMGA) oncoproteins in breast cancer: learning from the past to design future strategies. Expert Opinion on Therapeutic Targets 24:10, pages 953-969.
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Azhar Jabareen, Aya Abu-Jaafar, Ammar Abou-Kandil & Mahmoud Huleihel. (2017) Effect of TPA and HTLV-1 Tax on BRCA1 and ERE controlled genes expression. Cell Cycle 16:14, pages 1336-1344.
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Haipeng Wang, Zengjun Li, Yanlai Sun, Zhongfa Xu, Jianjun Han, Bao Song, Wentao Song, Chen Qin & Lei Yin. (2015) Relationship between high-mobility group box 1 overexpression in ovarian cancer tissue and serum: a meta-analysis. OncoTargets and Therapy 8, pages 3523-3531.
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Andrea BISSO, Michela Faleschini, Federico Zampa, Valeria Capaci, Jacopo De Santa, Libero Santarpia, Silvano Piazza, Vera Cappelletti, Mariagrazia Daidone, Reuven Agami & Giannino Del Sal. (2013) Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer. Cell Cycle 12:11, pages 1679-1687.
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Konstantin J. Dedes, Paul M. Wilkerson, Daniel Wetterskog, Britta Weigelt, Alan Ashworth & Jorge S. Reis-Filho. (2011) Synthetic lethality of PARP inhibition in cancers lacking BRCA1 and BRCA2 mutations. Cell Cycle 10:8, pages 1192-1199.
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