Advanced search
Publication Cover
Molecular and Cellular Biology Volume 24, 2004 - Issue 11
Submit an article Journal homepage
17
Views
44
CrossRef citations to date
0
Altmetric
Mammalian Genetic Models with Minimal or Complex Phenotypes

Disruption of CCTβ2 Expression Leads to Gonadal Dysfunction

Suzanne Jackowski1 Departments of Infectious Diseases;2 Department of Molecular Sciences, University of Tennessee Health Science Center, Memphis, Tennessee38163Correspondence[email protected]
,
Jerold E. Rehg3 Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee38105
,
Yong-Mei Zhang1 Departments of Infectious Diseases
,
Jina Wang1 Departments of Infectious Diseases
,
Karen Miller1 Departments of Infectious Diseases
,
Pam Jackson1 Departments of Infectious Diseases
&
Mohammad A. Karim1 Departments of Infectious Diseases
 show all
Pages 4720-4733 | Received 21 Oct 2003, Accepted 07 Mar 2004, Published online: 27 Mar 2023

Citations (44)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Neale D. Ridgway. (2013) The role of phosphatidylcholine and choline metabolites to cell proliferation and survival. Critical Reviews in Biochemistry and Molecular Biology 48:1, pages 20-38.
Read now
Morgan D. Fullerton, Fatima Hakimuddin & Marica Bakovic. (2007) Developmental and Metabolic Effects of Disruption of the Mouse CTP:Phosphoethanolamine Cytidylyltransferase Gene (Pcyt2). Molecular and Cellular Biology 27:9, pages 3327-3336.
Read now
Yong Tian, Ruobing Zhou, Jerold E. Rehg & Suzanne Jackowski. (2007) Role of Phosphocholine Cytidylyltransferase α in Lung Development. Molecular and Cellular Biology 27:3, pages 975-982.
Read now
Limin Wang, Susan Magdaleno, Ira Tabas & Suzanne Jackowski. (2005) Early Embryonic Lethality in Mice with Targeted Deletion of the CTP:Phosphocholine Cytidylyltransferase α Gene (Pcyt1a). Molecular and Cellular Biology 25:8, pages 3357-3363.
Read now

Articles from other publishers (40)

Yuta Ogasawara, Jinglei Cheng, Tsuyako Tatematsu, Misaki Uchida, Omi Murase, Shogo Yoshikawa, Yuki Ohsaki & Toyoshi Fujimoto. (2020) Long-term autophagy is sustained by activation of CCTβ3 on lipid droplets. Nature Communications 11:1.
Crossref
Lambert Yue, Michael J. McPhee, Kevin Gonzalez, Mark Charman, Jonghwa Lee, Jordan Thompson, Dirk F. H. Winkler, Rosemary B. Cornell, Steven Pelech & Neale D. Ridgway. (2020) Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets. Molecular Biology of the Cell 31:10, pages 1047-1059.
Crossref
Sumitra Pati, Lishann M. Ingram, Min K. Sun, John J. Wagner & Brian S. Cummings. (2019) Localization and expression of CTP: Phosphocholine cytidylyltransferase in rat brain following cocaine exposure. Journal of Chemical Neuroanatomy 96, pages 1-6.
Crossref
Jonghwa Lee & Neale D. Ridgway. (2018) Phosphatidylcholine synthesis regulates triglyceride storage and chylomicron secretion by Caco2 cells. Journal of Lipid Research 59:10, pages 1940-1950.
Crossref
Afreen Haider, Yu-Chen Wei, Koini Lim, Antonio D. Barbosa, Che-Hsiung Liu, Ursula Weber, Marek Mlodzik, Kadri Oras, Simon Collier, M. Mahmood Hussain, Liang Dong, Satish Patel, Anna Alvarez-Guaita, Vladimir Saudek, Benjamin J. Jenkins, Albert Koulman, Marcus K. Dymond, Roger C. Hardie, Symeon Siniossoglou & David B. Savage. (2018) PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress. Developmental Cell 45:4, pages 481-495.e8.
Crossref
Christopher R. McMaster. (2017) From yeast to humans – roles of the Kennedy pathway for phosphatidylcholine synthesis. FEBS Letters 592:8, pages 1256-1272.
Crossref
Jelske N. van der Veen, John P. Kennelly, Sereana Wan, Jean E. Vance, Dennis E. Vance & René L. Jacobs. (2017) The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease. Biochimica et Biophysica Acta (BBA) - Biomembranes 1859:9, pages 1558-1572.
Crossref
Joseph W. Brewer, Viktoriya Solodushko, Ileana Aragon & Robert A. Barrington. (2016) Phosphatidylcholine as a metabolic cue for determining B cell fate and function. Cellular Immunology 310, pages 78-88.
Crossref
Timothy D. Heden, P. Darrell Neufer & Katsuhiko Funai. (2016) Looking Beyond Structure: Membrane Phospholipids of Skeletal Muscle Mitochondria. Trends in Endocrinology & Metabolism 27:8, pages 553-562.
Crossref
Rosemary B. Cornell. (2016) Membrane lipid compositional sensing by the inducible amphipathic helix of CCT. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1861:8, pages 847-861.
Crossref
Rosemary B. Cornell & Neale D. Ridgway. (2015) CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis. Progress in Lipid Research 59, pages 147-171.
Crossref
Yueh-Chiang Hu & Satoshi H Namekawa. (2015) Functional significance of the sex chromosomes during spermatogenesis. REPRODUCTION 149:6, pages R265-R277.
Crossref
Rodrigo Fernández-Bussy, Valeria Mouguelar, Claudia Banchio & Gabriela Coux. (2013) Expression of phosphatidylcholine biosynthetic enzymes during early embryogenesis in the amphibian Bufo arenarum . Zygote 23:2, pages 257-265.
Crossref
Susanne E. Horvath & Günther Daum. (2013) Lipids of mitochondria. Progress in Lipid Research 52:4, pages 590-614.
Crossref
Paolo Fagone & Suzanne Jackowski. (2013) Phosphatidylcholine and the CDP–choline cycle. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1831:3, pages 523-532.
Crossref
Daniel J. Arsenault, Byong H. Yoo, Kirill V. Rosen & Neale D. Ridgway. (2013) ras-induced Up-regulation of CTP:Phosphocholine Cytidylyltransferase α Contributes to Malignant Transformation of Intestinal Epithelial Cells. Journal of Biological Chemistry 288:1, pages 633-643.
Crossref
Jana Strakova, Laurent Demizieux, Robert B. Campenot, Dennis E. Vance & Jean E. Vance. (2011) Involvement of CTP:phosphocholine cytidylyltransferase-β2 in axonal phosphatidylcholine synthesis and branching of neurons. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1811:10, pages 617-625.
Crossref
Martin Hermansson, Kati Hokynar & Pentti Somerharju. (2011) Mechanisms of glycerophospholipid homeostasis in mammalian cells. Progress in Lipid Research 50:3, pages 240-257.
Crossref
Melissa K. Dennis, Svetla G. Taneva & Rosemary B. Cornell. (2011) The Intrinsically Disordered Nuclear Localization Signal and Phosphorylation Segments Distinguish the Membrane Affinity of Two Cytidylyltransferase Isoforms. Journal of Biological Chemistry 286:14, pages 12349-12360.
Crossref
Luciana Paoletti, Claudia Elena, Pablo Domizi & Claudia Banchio. (2011) Role of Phosphatidylcholine during Neuronal differentiation. IUBMB Life, pages n/a-n/a.
Crossref
Hebe Marcucci, Luciana Paoletti, Suzanne Jackowski & Claudia Banchio. (2010) Phosphatidylcholine Biosynthesis during Neuronal Differentiation and Its Role in Cell Fate Determination. Journal of Biological Chemistry 285:33, pages 25382-25393.
Crossref
Mark A. Edson, Ankur K. Nagaraja & Martin M. Matzuk. (2009) The Mammalian Ovary from Genesis to Revelation. Endocrine Reviews 30:6, pages 624-712.
Crossref
Roberta Leonardi, Matthew W. Frank, Pamela D. Jackson, Charles O. Rock & Suzanne Jackowski. (2009) Elimination of the CDP-ethanolamine Pathway Disrupts Hepatic Lipid Homeostasis. Journal of Biological Chemistry 284:40, pages 27077-27089.
Crossref
Dennis E. Vance & Jean E. Vance. (2009) Physiological consequences of disruption of mammalian phospholipid biosynthetic genes. Journal of Lipid Research 50, pages S132-S137.
Crossref
Paolo Fagone, Christopher Gunter, Christopher R. Sage, Kathryn E. Gunn, Joseph W. Brewer & Suzanne Jackowski. (2009) CTP:Phosphocholine Cytidylyltransferase α Is Required for B-cell Proliferation and Class Switch Recombination. Journal of Biological Chemistry 284:11, pages 6847-6854.
Crossref
Yong Tian, Caroline Pate, Alberto Andreolotti, Limin Wang, Elaine Tuomanen, Kelli Boyd, Enrique Claro & Suzanne Jackowski. (2008) Cytokine secretion requires phosphatidylcholine synthesis. Journal of Cell Biology 181:6, pages 945-957.
Crossref
Zhaoyu Li & Dennis E. Vance. (2008) Thematic Review Series: Glycerolipids. Phosphatidylcholine and choline homeostasis. Journal of Lipid Research 49:6, pages 1187-1194.
Crossref
Dennis E Vance. (2008) Role of phosphatidylcholine biosynthesis in the regulation of lipoprotein homeostasis. Current Opinion in Lipidology 19:3, pages 229-234.
Crossref
Hebe Marcucci, Claudia Elena, Paola Gilardoni & Claudia Banchio. (2008) Characterization of the murine CTP:phosphocholine cytidylyltransferase beta gene promoter. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1781:5, pages 254-262.
Crossref
Gengshu Wu, Chieko Aoyama, Stephen G. Young & Dennis E. Vance. (2008) Early Embryonic Lethality Caused by Disruption of the Gene for Choline Kinase α, the First Enzyme in Phosphatidylcholine Biosynthesis. Journal of Biological Chemistry 283:3, pages 1456-1462.
Crossref
Jodi M. Carter, Laurent Demizieux, Robert B. Campenot, Dennis E. Vance & Jean E. Vance. (2008) Phosphatidylcholine Biosynthesis via CTP:Phosphocholine Cytidylyltransferase β2 Facilitates Neurite Outgrowth and Branching. Journal of Biological Chemistry 283:1, pages 202-212.
Crossref
Dennis E. Vance & Jean E. Vance. 2008. Biochemistry of Lipids, Lipoproteins and Membranes. Biochemistry of Lipids, Lipoproteins and Membranes 213 244 .
Dennis E. Vance, Zhaoyu Li & René L. Jacobs. (2007) Hepatic Phosphatidylethanolamine N-Methyltransferase, Unexpected Roles in Animal Biochemistry and Physiology. Journal of Biological Chemistry 282:46, pages 33237-33241.
Crossref
Christopher Gunter, Matthew Frank, Yong Tian, K. Gopal Murti, Jerold E. Rehg & Suzanne Jackowski. (2007) Probucol therapy overcomes the reproductive defect in CTP: phosphocholine cytidylyltransferase β2 knockout mice. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1771:7, pages 845-852.
Crossref
Marica BakovicMorgan D. FullertonVera Michel. (2007) Metabolic and molecular aspects of ethanolamine phospholipid biosynthesis: the role of CTP:phosphoethanolamine cytidylyltransferase (Pcyt2). Biochemistry and Cell Biology 85:3, pages 283-300.
Crossref
Athanasios Lykidis. (2007) Comparative genomics and evolution of eukaryotic phospholipid biosynthesis. Progress in Lipid Research 46:3-4, pages 171-199.
Crossref
Paolo Fagone, Rungtawan Sriburi, Cheryl Ward-Chapman, Matthew Frank, Jina Wang, Christopher Gunter, Joseph W. Brewer & Suzanne Jackowski. (2007) Phospholipid Biosynthesis Program Underlying Membrane Expansion during B-lymphocyte Differentiation. Journal of Biological Chemistry 282:10, pages 7591-7605.
Crossref
Jean E. Vance & Dennis E. Vance. (2005) Metabolic Insights into Phospholipid Function Using Gene-targeted Mice. Journal of Biological Chemistry 280:12, pages 10877-10880.
Crossref
Suzanne Jackowski & Paolo Fagone. (2005) CTP:Phosphocholine Cytidylyltransferase: Paving the Way from Gene to Membrane. Journal of Biological Chemistry 280:2, pages 853-856.
Crossref
Rungtawan Sriburi, Suzanne Jackowski, Kazutoshi Mori & Joseph W. Brewer. (2004) XBP1. The Journal of Cell Biology 167:1, pages 35-41.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.