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Molecular and Cellular Biology Volume 24, 2004 - Issue 15
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Cell Growth and Development

Association of Active Caspase 8 with the Mitochondrial Membrane during Apoptosis: Potential Roles in Cleaving BAP31 and Caspase 3 and Mediating Mitochondrion-Endoplasmic Reticulum Cross Talk in Etoposide-Induced Cell Death

Dhyan Chandra1 Department of Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, Texas78957
,
Grace Choy1 Department of Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, Texas78957
,
Xiaodi Deng1 Department of Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, Texas78957
,
Bobby Bhatia1 Department of Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, Texas78957
,
Peter Daniel2 Department of Hematology, Oncology, and Tumor Immunology, University Medical Center Charité, Humboldt University of Berlin, Berlin13125, Germany
&
Dean G. Tang1 Department of Carcinogenesis, University of Texas M. D. Anderson Cancer Center, Science Park-Research Division, Smithville, Texas78957Correspondence[email protected]
Pages 6592-6607 | Received 29 Dec 2003, Accepted 27 Apr 2004, Published online: 27 Mar 2023

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Crossref
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Crossref
Jun-Young Park, Yu-Jin Jeong, Sung-Kyun Park, Sung-Jin Yoon, Song Choi, Dae Jeong, Su Chung, Byung Lee, Jeong Kim, Vernon Tesh, Moo-Seung Lee & Young-Jun Park. (2017) Shiga Toxins Induce Apoptosis and ER Stress in Human Retinal Pigment Epithelial Cells. Toxins 9:10, pages 319.
Crossref
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Crossref
Pamela Ovadje, Saleem Ammar, Jose-Antonio Guerrero, John Thor Arnason & Siyaram Pandey. (2016) Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways. Oncotarget 7:45, pages 73080-73100.
Crossref
Qing Lu, Donovan Tucker, Yan Dong, Ningjun Zhao & Quanguang Zhang. (2015) Neuroprotective and Functional Improvement Effects of Methylene Blue in Global Cerebral Ischemia. Molecular Neurobiology 53:8, pages 5344-5355.
Crossref
M Lopez-Cruzan, R Sharma, M Tiwari, S Karbach, D Holstein, C R Martin, J D Lechleiter & B Herman. (2016) Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment. Cell Death Discovery 2:1.
Crossref
Fernando J. Reyes-Zurita, Eva E. Rufino-Palomares, Leticia García-Salguero, Juan Peragón, Pedro P. Medina, Andrés Parra, Marta Cascante & José A. Lupiáñez. (2016) Maslinic Acid, a Natural Triterpene, Induces a Death Receptor-Mediated Apoptotic Mechanism in Caco-2 p53-Deficient Colon Adenocarcinoma Cells. PLOS ONE 11:1, pages e0146178.
Crossref
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Crossref
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Crossref
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Crossref
OSAMU SUZUKI, MASAFUMI ABE & YUKO HASHIMOTO. (2015) Caspase-dependent drug-induced apoptosis is regulated by cell surface sialylation in human B-cell lymphoma. Oncology Letters 10:2, pages 687-690.
Crossref
E S Marini, C Giampietri, S Petrungaro, S Conti, A Filippini, L Scorrano & E Ziparo. (2014) The endogenous caspase-8 inhibitor c-FLIPL regulates ER morphology and crosstalk with mitochondria. Cell Death & Differentiation 22:7, pages 1131-1143.
Crossref
Kritarth Singh, Anastasia Poteryakhina, Andrei Zheltukhin, Khyati Bhatelia, Paresh Prajapati, Lakshmi Sripada, Dhanendra Tomar, Rochika Singh, Arun K. Singh, Peter M. Chumakov & Rajesh Singh. (2015) NLRX1 acts as tumor suppressor by regulating TNF-α induced apoptosis and metabolism in cancer cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1853:5, pages 1073-1086.
Crossref
Yu-Hsiang Chang, Wohn-Jenn Leu, Amitabha Datta, Hung-Chang Hsiao, Chia-Her Lin, Jih-Hwa Guh & Jui-Hsien Huang. (2015) Catalytic transfer hydrogenation and anticancer activity of arene–ruthenium compounds incorporating bi-dentate precursors. Dalton Transactions 44:36, pages 16107-16118.
Crossref
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Crossref
Su-Wen Lim, Hwei-San Loh, Kang-Nee Ting, Tracey D Bradshaw & Nazariah A Zeenathul. (2014) Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells. BMC Complementary and Alternative Medicine 14:1.
Crossref
Su-Wen Lim, Hwei-San Loh, Kang Nee Ting, Tracey D. Bradshaw & Nazariah A. Zeenathul. (2014) Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines. Biomedicine & Pharmacotherapy 68:8, pages 1105-1115.
Crossref
Seyedeh Fatemeh Jafari, Mohamed B Khadeer Ahamed, Muhammad Adnan Iqbal, Fouad Saleih R Al Suede, Syed Haroon Khalid, Rosenani A Haque, Zeyad D Nassar, Muhammad Ihtisham Umar & Amin Malik Shah Abdul Majid. (2014) Increased aqueous solubility and proapoptotic activity of potassium koetjapate against human colorectal cancer cells. Journal of Pharmacy and Pharmacology 66:10, pages 1394-1409.
Crossref
Carine B. Bourguet, Pierre-Luc Boulay, Audrey Claing & William D. Lubell. (2014) Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells. Bioorganic & Medicinal Chemistry Letters 24:15, pages 3361-3365.
Crossref
Jinheng WangAn Hendrix, Sophie Hernot, Miguel LemaireElke De BruyneEls Van ValckenborghTony Lahoutte, Olivier De Wever, Karin VanderkerkenEline Menu. (2014) Bone marrow stromal cell–derived exosomes as communicators in drug resistance in multiple myeloma cells. Blood 124:4, pages 555-566.
Crossref
You-Cheng Hseu, Chuan-Chen Lee, Yung-Chang Chen, K.J. Senthil Kumar, Chee-Shan Chen, Yu-Chi Huang, Li-Sung Hsu, Hui-Chi Huang & Hsin-Ling Yang. (2014) The anti-tumor activity of Antrodia salmonea in human promyelocytic leukemia (HL-60) cells is mediated via the induction of G1 cell-cycle arrest and apoptosis in vitro or in vivo. Journal of Ethnopharmacology 153:2, pages 499-510.
Crossref
Richard T Williams, Alice L Yu, Mitchell B Diccianni, Emmanuel A Theodorakis & Ayse Batova. (2013) Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy. Journal of Experimental & Clinical Cancer Research 32:1.
Crossref
Weijie Gao, Fenglian Xiao, Xiaoping Wang & Tongsheng Chen. (2013) Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3. Apoptosis 18:10, pages 1201-1213.
Crossref
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Crossref
Olivier Jalmar, Liberty François-Moutal, Ana-Jesus García-Sáez, Mark Perry, Thierry Granjon, François Gonzalvez, Eyal Gottlieb, Jesus Ayala-Sanmartin, Beate Klösgen, Petra Schwille & Patrice X. Petit. (2013) Caspase-8 Binding to Cardiolipin in Giant Unilamellar Vesicles Provides a Functional Docking Platform for Bid. PLoS ONE 8:2, pages e55250.
Crossref
Raghu Gogada, Neelu Yadav, Junwei Liu, Shaohua Tang, Dianmu Zhang, Andrea Schneider, Athul Seshadri, Leimin Sun, C. Marcelo Aldaz, Dean G. Tang & Dhyan Chandra. (2013) Bim, a Proapoptotic Protein, Up-regulated via Transcription Factor E2F1-dependent Mechanism, Functions as a Prosurvival Molecule in Cancer. Journal of Biological Chemistry 288:1, pages 368-381.
Crossref
Kaiyu He, Hui-Ren Zhou & James J. Pestka. (2012) Mechanisms for ribotoxin-induced ribosomal RNA cleavage. Toxicology and Applied Pharmacology 265:1, pages 10-18.
Crossref
Lanhai Lü, Lihong Zhang, Maria Sen Mun Wai, David Tai Wai Yew & Jie Xu. (2012) Exocytosis of MTT formazan could exacerbate cell injury. Toxicology in Vitro 26:4, pages 636-644.
Crossref
Fenglian Xiao, Weijie Gao, Xiaoping Wang & Tongsheng Chen. (2012) Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells. Apoptosis 17:6, pages 600-611.
Crossref
Diana C. West, Yan Qin, Quinn P. Peterson, Diana L. Thomas, Rahul Palchaudhuri, Karen C. Morrison, Pamela W. Lucas, Amy E. Palmer, Timothy M. Fan & Paul J. Hergenrother. (2012) Differential Effects of Procaspase-3 Activating Compounds in the Induction of Cancer Cell Death. Molecular Pharmaceutics 9:5, pages 1425-1434.
Crossref
Junichi Matsuzaki, Toshihiko Torigoe, Yoshihiko Hirohashi, Kenjiro Kamiguchi, Yasuaki Tamura, Tomohide Tsukahara, Terufumi Kubo, Akari Takahashi, Emiri Nakazawa, Eri Saka, Kazuyo Yasuda, Shuji Takahashi & Noriyuki Sato. (2012) ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells. Carcinogenesis 33:5, pages 996-1003.
Crossref
S Wang, P Xia, L Shi & Z Fan. (2011) FADD cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase cascade. Cell Death & Differentiation 19:4, pages 605-615.
Crossref
Hannah M. Heath-Engel, Bing Wang & Gordon C. Shore. (2012) Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:2, pages 335-347.
Crossref
Stefan Grimm. (2012) The ER–mitochondria interface: The social network of cell death. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1823:2, pages 327-334.
Crossref
Gerald W DornIIII & Richard N. Kitsis. 2012. Muscle. Muscle 423 446 .
Raghu Gogada, Varun Prabhu, Michael Amadori, Rachael Scott, Sana Hashmi & Dhyan Chandra. (2011) Resveratrol Induces p53-independent, X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Bax Protein Oligomerization on Mitochondria to Initiate Cytochrome c Release and Caspase Activation. Journal of Biological Chemistry 286:33, pages 28749-28760.
Crossref
LingYi Dong, KeWei Jiang, YanBin Zhang, Hui Zhang, HongQing Zhuo, ZhiRong Cui, YingJiang Ye & Shan Wang. (2011) BAP31 is frequently overexpressed in patients with primary colorectal cancer and correlates with better prognosis. Chinese Science Bulletin 56:23, pages 2444-2449.
Crossref
Clarissa von Haefen, Jana Wendt, Geo Semini, Marco Sifringer, Claus Belka, Silke Radetzki, Werner Reutter, Peter T. Daniel & Kerstin Danker. (2011) Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway. Apoptosis 16:6, pages 636-651.
Crossref
Z T Schug, F Gonzalvez, R H Houtkooper, F M Vaz & E Gottlieb. (2010) BID is cleaved by caspase-8 within a native complex on the mitochondrial membrane. Cell Death & Differentiation 18:3, pages 538-548.
Crossref
Byeong Mo Kim & Sung Hee Hong. (2010) Sequential caspase-2 and caspase-8 activation is essential for saikosaponin a-induced apoptosis of human colon carcinoma cell lines. Apoptosis 16:2, pages 184-197.
Crossref
Honghao Zhang, Raghu Gogada, Neelu Yadav, Ravi K. Lella, Mark Badeaux, Mary Ayres, Varsha Gandhi, Dean G. Tang & Dhyan Chandra. (2011) Defective Molecular Timer in the Absence of Nucleotides Leads to Inefficient Caspase Activation. PLoS ONE 6:1, pages e16379.
Crossref
Alex D Chacko, Fabio Liberante, Ian Paul, Daniel B Longley & Dean A Fennell. (2010) Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8. BMC Cancer 10:1.
Crossref
Byeong Mo Kim, Yun Jung Choi, Yong Heon Lee, Young Ae Joe & Sung Hee Hong. (2010) N,N-Dimethyl phytosphingosine sensitizes HL-60/MX2, a multidrug-resistant variant of HL-60 cells, to doxorubicin-induced cytotoxicity through ROS-mediated release of cytochrome c and AIF. Apoptosis 15:8, pages 982-993.
Crossref
Vernon L Tesh. (2010) Induction of apoptosis by Shiga toxins. Future Microbiology 5:3, pages 431-453.
Crossref
Dayong Zhai, Eric Yu, Chaofang Jin, Kate Welsh, Chung-wei Shiau, Lili Chen, Guy S. Salvesen, Robert Liddington & John C. Reed. (2010) Vaccinia Virus Protein F1L Is a Caspase-9 Inhibitor. Journal of Biological Chemistry 285:8, pages 5569-5580.
Crossref
Hirofumi Inoue, Takumi Uyama, Tsukasa Suzuki, Machiko Kazami, Okio Hino, Toshiyuki Kobayashi, Ken-Ichi Kobayashi, Tadahiro Tadokoro & Yuji Yamamoto. (2010) Phosphorylated hamartin–Hsp70 complex regulates apoptosis via mitochondrial localization. Biochemical and Biophysical Research Communications 391:1, pages 1148-1153.
Crossref
J.J. Lemasters. 2010. Comprehensive Toxicology. Comprehensive Toxicology 245 268 .
V Mamidipudi & C A Cartwright. (2009) A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways. Oncogene 28:50, pages 4421-4433.
Crossref
Joseph E. Aslan & Gary Thomas. (2009) Death by Committee: Organellar Trafficking and Communication in Apoptosis. Traffic 10:10, pages 1390-1404.
Crossref
Chaojun SongBinyuan YanLihua ChenYongming LiYuying WeiYuanjie SunAngang YangKun YangBoquan Jin. (2009) Novel Immunohistochemical Monoclonal Antibody Against Rat B Cell Receptor Associated Protein 31 (BAP31). Hybridoma 28:5, pages 363-367.
Crossref
Hyo-Jin KimHo-June LeeJoon-Il JunYumin OhSeon-Guk ChoiHyunjoo KimChul-Woong ChungIn-Ki KimIl-Sun ParkHan-Jung Chae, Hyung-Ryong Kim & Yong-Keun Jung. (2009) Intracellular cleavage of osteopontin by caspase-8 modulates hypoxia/reoxygenation cell death through p53. Proceedings of the National Academy of Sciences 106:36, pages 15326-15331.
Crossref
Byeong Mo Kim, Yun Jung Choi, Youngsoo Han, Yeon-Sook Yun & Sung Hee Hong. (2009) N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells. Toxicology and Applied Pharmacology 239:1, pages 87-97.
Crossref
Chaojun SongFuli WangZhuwei XuJintao HuHaiqiang TaoAngang YangKun YangBoquan Jin. (2009) Monoclonal Antibodies Against Human BAP31 for Immunocytochemistry. Hybridoma 28:3, pages 177-181.
Crossref
Kimiko Kadohara, Michiko Nagumo, Shun Asami, Yoshinori Tsukumo, Hikaru Sugimoto, Masayuki Igarashi, Kazuo Nagai & Takao Kataoka. (2009) Caspase-8 Mediates Mitochondrial Release of Pro-apoptotic Proteins in a Manner Independent of Its Proteolytic Activity in Apoptosis Induced by the Protein Synthesis Inhibitor Acetoxycycloheximide in Human Leukemia Jurkat Cells. Journal of Biological Chemistry 284:9, pages 5478-5487.
Crossref
F. Alexandra Loucks, Emily K. Schroeder, Amelia E. Zommer, Shea Hilger, Natalie A. Kelsey, Ron J. Bouchard, Craig Blackstone, Jay L. Brewster & Daniel A. Linseman. (2009) Caspases indirectly regulate cleavage of the mitochondrial fusion GTPase OPA1 in neurons undergoing apoptosis. Brain Research 1250, pages 63-74.
Crossref
Dhyan Chandra & Dean G. Tang. 2009. Apoptosis. Apoptosis 65 75 .
Hui Peng, Augusto Sola, James Moore & Tongchun Wen. (2009) Caspase inhibition by cardiotrophin-1 prevents neuronal death in vivo and in vitro. Journal of Neuroscience Research, pages NA-NA.
Crossref
Francois Gonzalvez, Zachary T. Schug, Riekelt H. Houtkooper, Elaine D. MacKenzie, David G. Brooks, Ronald J.A. Wanders, Patrice X. Petit, Frédéric M. Vaz & Eyal Gottlieb. (2008) Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. Journal of Cell Biology 183:4, pages 681-696.
Crossref
Dharmalingam Subramaniam, Periyasamy Giridharan, Nabendu Murmu, Nallakandy P. Shankaranarayanan, Randal May, Courtney W. Houchen, Rama P. Ramanujam, Arun Balakrishnan, Ram A. Vishwakarma & Shrikant Anant. (2008) Activation of Apoptosis by 1-Hydroxy-5,7-Dimethoxy-2-Naphthalene-Carboxaldehyde, a Novel Compound from Aegle marmelos . Cancer Research 68:20, pages 8573-8581.
Crossref
E Gyan, E Frisan, O Beyne-Rauzy, J-C Deschemin, C Pierre-Eugene, C Randriamampita, A Dubart-Kupperschmitt, C Garrido, F Dreyfus, P Mayeux, C Lacombe, E Solary & M Fontenay. (2008) Spontaneous and Fas-induced apoptosis of low-grade MDS erythroid precursors involves the endoplasmic reticulum. Leukemia 22:10, pages 1864-1873.
Crossref
Laura Padrón-Barthe, Jacqueline Courta, Chloé Leprêtre, Atf Nagbou & Alicia Torriglia. (2008) Leukocyte Elastase Inhibitor, the precursor of L-DNase II, inhibits apoptosis by interfering with caspase-8 activation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1783:10, pages 1755-1766.
Crossref
Ronald L. Mellgren. (2008) Detergent-resistant membrane subfractions containing proteins of plasma membrane, mitochondrial, and internal membrane origins. Journal of Biochemical and Biophysical Methods 70:6, pages 1029-1036.
Crossref
Chi Chen, Peter G Fuhrken, Li Ting Huang, Pani Apostolidis, Min Wang, Carlos J Paredes, William M Miller & Eleftherios T Papoutsakis. (2007) A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis. BMC Genomics 8:1.
Crossref
Wilma Dormeyer, Shabaz Mohammed, Bas van Breukelen, Jeroen Krijgsveld & Albert J. R. Heck. (2007) Targeted Analysis of Protein Termini. Journal of Proteome Research 6:12, pages 4634-4645.
Crossref
Ho-June Lee, Jong-Ok Pyo, Yumin Oh, Hyo-Jin Kim, Se-hoon Hong, Young-Jun Jeon, Hyunjoo Kim, Dong-Hyung Cho, Ha-Na Woo, Sungmin Song, Jung-Hyun Nam, Hyo Joon Kim, Key-Sun Kim & Yong-Keun Jung. (2007) AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10. Nature Cell Biology 9:11, pages 1303-1310.
Crossref
Toru Iizaka, Mayumi Tsuji, Hideto Oyamada, Yuri Morio & Katsuji Oguchi. (2007) Interaction between caspase-8 activation and endoplasmic reticulum stress in glycochenodeoxycholic acid-induced apoptotic HepG2 cells. Toxicology 241:3, pages 146-156.
Crossref
Huali Jin, Chong Xiao, Gan Zhao, Xiaogang Du, Yang Yu, Youmin Kang & Bin Wang. (2007) Induction of immature dendritic cell apoptosis by foot and mouth disease virus is an integrin receptor mediated event before viral infection. Journal of Cellular Biochemistry 102:4, pages 980-991.
Crossref
Dhyan Chandra, Grace Choy & Dean G. Tang. (2007) Cytosolic Accumulation of HSP60 during Apoptosis with or without Apparent Mitochondrial Release. Journal of Biological Chemistry 282:43, pages 31289-31301.
Crossref
Heidi K. Baumgartner, Julia V. Gerasimenko, Christopher Thorne, Louise H. Ashurst, Stephanie L. Barrow, Michael A. Chvanov, Stuart Gillies, David N. Criddle, Alexei V. Tepikin, Ole H. Petersen, Robert Sutton, Alastair J. M. Watson & Oleg V. Gerasimenko. (2007) Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins. American Journal of Physiology-Gastrointestinal and Liver Physiology 293:1, pages G296-G307.
Crossref
Jianbei Zhu, Ying Yang & Jiarui Wu. (2007) Bcl-2 cleavages at two adjacent sites by different caspases promote cisplatin-induced apoptosis. Cell Research 17:5, pages 441-448.
Crossref
Vladimir Voccoli, Francesca Mazzoni, Mercedes Garcia-Gil & Laura Colombaioni. (2007) Serum-withdrawal-dependent apoptosis of hippocampal neuroblasts involves Ca++ release by endoplasmic reticulum and caspase-12 activation. Brain Research 1147, pages 1-11.
Crossref
Naama Peshes-Yaloz, Dalia Rosen, Paul M. Sondel, Peter H. Krammer & Gideon Berke. (2007) Up-regulation of Fas (CD95) expression in tumour cells in vivo. Immunology 120:4, pages 502-511.
Crossref
Frédéric Delom, Delphine Fessart & Eric Chevet. (2007) Regulation of calnexin sub-cellular localization modulates endoplasmic reticulum stress-induced apoptosis in MCF-7 cells. Apoptosis 12:2, pages 293-305.
Crossref
Kristijana Milovic-Holm, Eva Krieghoff, Kirsten Jensen, Hans Will & Thomas G Hofmann. (2007) FLASH links the CD95 signaling pathway to the cell nucleus and nuclear bodies. The EMBO Journal 26:2, pages 391-401.
Crossref
Dong-Joon Min, Naomi P. Moskowitz, Carrie Brownstein, Hokyung Lee, Terzah M. Horton & William L. Carroll. (2006) Diverse pathways mediate chemotherapy-induced cell death in acute lymphoblastic leukemia cell lines. Apoptosis 11:11, pages 1977-1986.
Crossref
Duncan T. Browman, Mary E. Resek, Laura D. Zajchowski & Stephen M. Robbins. (2006) Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER. Journal of Cell Science 119:15, pages 3149-3160.
Crossref
Po-Lin Kuo, Ya-Ling Hsu, Chien-Yu Cho, Lean-Teik Ng, Yueh-Hsiung Kuo & Chun-Ching Lin. (2006) Apoptotic effects of Antrodia cinnamomea fruiting bodies extract are mediated through calcium and calpain-dependent pathways in Hep 3B cells. Food and Chemical Toxicology 44:8, pages 1316-1326.
Crossref
Na Liu, Virginia L. Scofield, Wenan Qiang, Mingshan Yan, Xianghong Kuang & Paul K.Y. Wong. (2006) Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes. Virology 348:2, pages 398-405.
Crossref
Soo Jung Kim, Kyung Mi Park, Nayoung Kim & Young Il Yeom. (2006) Doxorubicin prevents endoplasmic reticulum stress-induced apoptosis. Biochemical and Biophysical Research Communications 339:2, pages 463-468.
Crossref
Frances J. Northington, Ernest M. Graham & Lee J. Martin. (2005) Apoptosis in perinatal hypoxic–ischemic brain injury: How important is it and should it be inhibited?. Brain Research Reviews 50:2, pages 244-257.
Crossref
Christian Scholz, Antje Richter, Mario Lehmann, Klaus Schulze-Osthoff, Bernd Dörken & Peter T Daniel. (2005) Arsenic trioxide induces regulated, death receptor-independent cell death through a Bcl-2-controlled pathway. Oncogene 24:47, pages 7031-7042.
Crossref
Marina Stojanovic, Marc Germain, Mai Nguyen & Gordon C. Shore. (2005) BAP31 and Its Caspase Cleavage Product Regulate Cell Surface Expression of Tetraspanins and Integrin-mediated Cell Survival. Journal of Biological Chemistry 280:34, pages 30018-30024.
Crossref
Tim Levine & Catherine Rabouille. (2005) Endoplasmic reticulum: one continuous network compartmentalized by extrinsic cues. Current Opinion in Cell Biology 17:4, pages 362-368.
Crossref
Tapan K. Mukherjee, Srirupa Mukhopadhyay & John R. Hoidal. (2005) The role of reactive oxygen species in TNFα-dependent expression of the receptor for advanced glycation end products in human umbilical vein endothelial cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1744:2, pages 213-223.
Crossref
Dhyan Chandra, Grace Choy, Peter T. Daniel & Dean G. Tang. (2005) Bax-dependent Regulation of Bak by Voltage-dependent Anion Channel 2. Journal of Biological Chemistry 280:19, pages 19051-19061.
Crossref
Jun Matsui, Nobutaka Kiyokawa, Hisami Takenouchi, Tomoko Taguchi, Kyoko Suzuki, Yusuke Shiozawa, Masahiro Saito, Wei-ran Tang, Yohko U. Katagiri, Hajime Okita & Junichiro Fujimoto. (2005) Dietary bioflavonoids induce apoptosis in human leukemia cells. Leukemia Research 29:5, pages 573-581.
Crossref
Zhigang Li, Heidi Y Shi & Ming Zhang. (2005) Targeted expression of maspin in tumor vasculatures induces endothelial cell apoptosis. Oncogene 24:12, pages 2008-2019.
Crossref
Jun-Wei Liu, Dhyan Chandra, Michael D Rudd, Andrew P Butler, Vincent Pallotta, David Brown, Paul J Coffer & Dean G Tang. (2005) Induction of prosurvival molecules by apoptotic stimuli: involvement of FOXO3a and ROS. Oncogene 24:12, pages 2020-2031.
Crossref
Thomas Simmen, Joseph E Aslan, Anastassia D Blagoveshchenskaya, Laurel Thomas, Lei Wan, Yang Xiang, Sylvain F Feliciangeli, Chien-Hui Hung, Colin M Crump & Gary Thomas. (2005) PACS-2 controls endoplasmic reticulum–mitochondria communication and Bid-mediated apoptosis. The EMBO Journal 24:4, pages 717-729.
Crossref
Grace Choy, Jun-Wei Liu, Dhyan Chandra & Dean G. Tang. 2005. Advances in Targeted Cancer Therapy. Advances in Targeted Cancer Therapy 115 145 .
Clarissa von Haefen, Bernhard Gillissen, Philipp G Hemmati, Jana Wendt, Dilek Güner, Alicja Mrozek, Claus Belka, Bernd Dörken & Peter T Daniel. (2004) Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway. Oncogene 23:50, pages 8320-8332.
Crossref

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