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Cell Growth and Development

p53 Stabilization and Accumulation Induced by Human Vaccinia-Related Kinase 1

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Pages 10366-10380 | Received 21 Dec 2003, Accepted 16 Aug 2004, Published online: 27 Mar 2023

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Alberto Valbuena, Francisco M. Vega, Sandra Blanco & Pedro A. Lazo. (2006) p53 Downregulates Its Activating Vaccinia-Related Kinase 1, Forming a New Autoregulatory Loop. Molecular and Cellular Biology 26:13, pages 4782-4793.
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Marta Sanz-García, Diana M. Monsalve, Ana Sevilla & Pedro A. Lazo. (2012) Vaccinia-related Kinase 1 (VRK1) Is an Upstream Nucleosomal Kinase Required for the Assembly of 53BP1 Foci in Response to Ionizing Radiation-induced DNA Damage. Journal of Biological Chemistry 287:28, pages 23757-23768.
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Rajan GognaEsha MadanPeriannan KuppusamyUttam Pati. (2012) Reactive Oxygen Species-Mediated p53 Core-Domain Modifications Determine Apoptotic or Necrotic Death in Cancer Cells. Antioxidants & Redox Signaling 16:5, pages 400-412.
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Wanil Kim, Goutam Chakraborty, Sangjune Kim, Joon Shin, Choon-Ho Park, Min-Woo Jeong, Nagakumar Bharatham, Ho Sup Yoon & Kyong-Tai Kim. (2012) Macro Histone H2A1.2 (MacroH2A1) Protein Suppresses Mitotic Kinase VRK1 during Interphase. Journal of Biological Chemistry 287:8, pages 5278-5289.
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Pedro A. Lazo & Claudio R. Santos. (2011) Interference with p53 functions in human viral infections, a target for novel antiviral strategies?. Reviews in Medical Virology, pages n/a-n/a.
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Choon-Ho Park, Bo-Hwa Choi, Min-Woo Jeong, Sangjune Kim, Wanil Kim, Yun Seon Song & Kyong-Tai Kim. (2011) Protein kinase Cδ regulates vaccinia-related kinase 1 in DNA damage–induced apoptosis. Molecular Biology of the Cell 22:8, pages 1398-1408.
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Carolyn S. Schober, Fulya Aydiner, Carmen J. Booth, Emre Seli & Valerie Reinke. (2011) The kinase VRK1 is required for normal meiotic progression in mammalian oogenesis. Mechanisms of Development 128:3-4, pages 178-190.
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Alberto Valbuena, Susana Castro-Obregón & Pedro A. Lazo. (2011) Downregulation of VRK1 by p53 in Response to DNA Damage Is Mediated by the Autophagic Pathway. PLoS ONE 6:2, pages e17320.
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Shikhar Sharma, Daniel D. De Carvalho, Shinwu Jeong, Peter A. Jones & Gangning Liang. (2011) Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance. PLoS Genetics 7:2, pages e1001286.
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Yoon Ha Choi, Choon-Ho Park, Wanil Kim, Hua Ling, Aram Kang, Matthew Wook Chang, Sun-Kyoung Im, Hyun-Woo Jeong, Young-Yun Kong & Kyong-Tai Kim. (2010) Vaccinia-Related Kinase 1 Is Required for the Maintenance of Undifferentiated Spermatogonia in Mouse Male Germ Cells. PLoS ONE 5:12, pages e15254.
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Yasutsugu Suzuki, Kanako Ogawa, Yoshio Koyanagi & Youichi Suzuki. (2010) Functional Disruption of the Moloney Murine Leukemia Virus Preintegration Complex by Vaccinia-related Kinases. Journal of Biological Chemistry 285:31, pages 24032-24043.
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Peter Tsvetkov, Nina Reuven, Carol Prives & Yosef Shaul. (2009) Susceptibility of p53 Unstructured N Terminus to 20 S Proteasomal Degradation Programs the Stress Response. Journal of Biological Chemistry 284:39, pages 26234-26242.
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Marta Sanz-Garciéa, Inmaculada Loépez-Saénchez & Pedro A. Lazo. (2008) Proteomics Identification of Nuclear Ran GTPase as an Inhibitor of Human VRK1 and VRK2 (Vaccinia-related Kinase) Activities. Molecular & Cellular Proteomics 7:11, pages 2199-2214.
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Nicola J. MacLaine, Bodil Øster, Bettina Bundgaard, Jennifer A. Fraser, Carolyn Buckner, Pedro A. Lazo, David W. Meek, Per Höllsberg & Ted R. Hupp. (2008) A Central Role for CK1 in Catalyzing Phosphorylation of the p53 Transactivation Domain at Serine 20 after HHV-6B Viral Infection. Journal of Biological Chemistry 283:42, pages 28563-28573.
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