Molecular and Cellular Biology, Volume 24, Issue 23 (2004)

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Molecular and Cellular Biology, Volume 24, Issue 23 (2004)

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Gene Expression

Article
Interaction between a G-Patch Protein and a Spliceosomal DEXD/H-Box ATPase That Is Critical for Splicing
Edward J. Silverman, Ayaka Maeda, Janet Wei, Paul Smith, Jean D. Beggs & Ren-Jang Lin
Pages: 10101-10110
Published online: 27 Mar 2023
AbstractforInteraction between a G-Patch Protein and a Spliceosomal DEXD/H-Box ATPase That Is Critical for Splicing | Full Text | References | PDF (456.7 KB)
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Article
3′-End Polishing of the Kinetoplastid Spliced Leader RNA Is Performed by SNIP, a 3′→5′ Exonuclease with a Motley Assortment of Small RNA Substrates
Gusti M. Zeiner, Robert A. Hitchcock, Nancy R. Sturm & David A. Campbell
Pages: 10390-10396
Published online: 27 Mar 2023
Abstractfor3′-End Polishing of the Kinetoplastid Spliced Leader RNA Is Performed by SNIP, a 3′→5′ Exonuclease with a Motley Assortment of Small RNA Substrates | Full Text | References | PDF (306.6 KB)
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Article
Yeast Shuttling SR Proteins Npl3p, Gbp2p, and Hrb1p Are Part of the Translating mRNPs, and Npl3p Can Function as a Translational Repressor
Merle Windgassen, Dorothée Sturm, Iván J. Cajigas, Carlos I. González, Matthias Seedorf, Holger Bastians & Heike Krebber
Pages: 10479-10491
Published online: 27 Mar 2023
AbstractforYeast Shuttling SR Proteins Npl3p, Gbp2p, and Hrb1p Are Part of the Translating mRNPs, and Npl3p Can Function as a Translational Repressor | Full Text | References | PDF (537.1 KB)
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Transcriptional Regulation

Article
Evidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II
Marc A. Schwabish & Kevin Struhl
Pages: 10111-10117
Published online: 27 Mar 2023
AbstractforEvidence for Eviction and Rapid Deposition of Histones upon Transcriptional Elongation by RNA Polymerase II | Full Text | References | PDF (429.7 KB)
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Article
Ski Negatively Regulates Erythroid Differentiation through Its Interaction with GATA1
Nobuhide Ueki, Leiqing Zhang & Michael J. Hayman
Pages: 10118-10125
Published online: 27 Mar 2023
AbstractforSki Negatively Regulates Erythroid Differentiation through Its Interaction with GATA1 | Full Text | References | PDF (318.1 KB)
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Article
Jumonji Represses Atrial Natriuretic Factor Gene Expression by Inhibiting Transcriptional Activities of Cardiac Transcription Factors
Tae-gyun Kim, Junqin Chen, Junich Sadoshima & Youngsook Lee
Pages: 10151-10160
Published online: 27 Mar 2023
AbstractforJumonji Represses Atrial Natriuretic Factor Gene Expression by Inhibiting Transcriptional Activities of Cardiac Transcription Factors | Full Text | References | PDF (331.9 KB)
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Article
Nuclear Speckle-Associated Protein Pnn/DRS Binds to the Transcriptional Corepressor CtBP and Relieves CtBP- Mediated Repression of the E-Cadherin Gene
Roman Alpatov, Gustavo Costa Munguba, Paul Caton, Jeong Hoon Joo, Yang Shi, Yujiang Shi, Marguerite E. Hunt & Stephen P. Sugrue
Pages: 10223-10235
Published online: 27 Mar 2023
AbstractforNuclear Speckle-Associated Protein Pnn/DRS Binds to the Transcriptional Corepressor CtBP and Relieves CtBP- Mediated Repression of the E-Cadherin Gene | Full Text | References | PDF (794 KB)
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Article
Human Matrix Attachment Regions Are Necessary for the Establishment but Not the Maintenance of Transgene Insulation in Drosophila melanogaster
Stephanie J. Namciu & R. E. K. Fournier
Pages: 10236-10245
Published online: 27 Mar 2023
AbstractforHuman Matrix Attachment Regions Are Necessary for the Establishment but Not the Maintenance of Transgene Insulation in Drosophila melanogaster | Full Text | References | PDF (741 KB)
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Article
Multiple, Distant Gata2 Enhancers Specify Temporally and Tissue-Specific Patterning in the Developing Urogenital System
Melin Khandekar, Norio Suzuki, Jon Lewton, Masayuki Yamamoto & James Douglas Engel
Pages: 10263-10276
Published online: 27 Mar 2023
AbstractforMultiple, Distant Gata2 Enhancers Specify Temporally and Tissue-Specific Patterning in the Developing Urogenital System | Full Text | References | PDF (1.4 MB)
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Article
Dependence of ORC Silencing Function on NatA-Mediated Nα Acetylation in Saccharomyces cerevisiae
Antje Geissenhöner, Christoph Weise & Ann E. Ehrenhofer-Murray
Pages: 10300-10312
Published online: 27 Mar 2023
AbstractforDependence of ORC Silencing Function on NatA-Mediated Nα Acetylation in Saccharomyces cerevisiae | Full Text | References | PDF (521.4 KB)
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Article
Stage-Specific Repression by the EKLF Transcriptional Activator
Xiaoyong Chen & James J. Bieker
Pages: 10416-10424
Published online: 27 Mar 2023
AbstractforStage-Specific Repression by the EKLF Transcriptional Activator | Full Text | References | PDF (440.2 KB)
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Article
Sox7 Plays Crucial Roles in Parietal Endoderm Differentiation in F9 Embryonal Carcinoma Cells through Regulating Gata-4 and Gata-6 Expression
Sugiko Futaki, Yoshitaka Hayashi, Tomomi Emoto, Charles N. Weber & Kiyotoshi Sekiguchi
Pages: 10492-10503
Published online: 27 Mar 2023
AbstractforSox7 Plays Crucial Roles in Parietal Endoderm Differentiation in F9 Embryonal Carcinoma Cells through Regulating Gata-4 and Gata-6 Expression | Full Text | References | PDF (493.6 KB)
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Dna Dynamics and Chromosome Structure

Article
A Tel1/MRX-Dependent Checkpoint Inhibits the Metaphase-to-Anaphase Transition after UV Irradiation in the Absence of Mec1
Michela Clerici, Veronica Baldo, Davide Mantiero, Francisca Lottersberger, Giovanna Lucchini & Maria Pia Longhese
Pages: 10126-10144
Published online: 27 Mar 2023
AbstractforA Tel1/MRX-Dependent Checkpoint Inhibits the Metaphase-to-Anaphase Transition after UV Irradiation in the Absence of Mec1 | Full Text | References | PDF (1.5 MB)
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Article
Yeast Chromatin Assembly Complex 1 Protein Excludes Nonacetylatable Forms of Histone H4 from Chromatin and the Nucleus
Lynn Glowczewski, Jakob H. Waterborg & Judith G. Berman
Pages: 10180-10192
Published online: 27 Mar 2023
AbstractforYeast Chromatin Assembly Complex 1 Protein Excludes Nonacetylatable Forms of Histone H4 from Chromatin and the Nucleus | Full Text | References | PDF (416 KB)
  • 15 Views
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Article
Transcription Factor Binding and Induced Transcription Alter Chromosomal c-myc Replicator Activity
M. Ghosh, G. Liu, G. Randall, J. Bevington & M. Leffak
Pages: 10193-10207
Published online: 27 Mar 2023
AbstractforTranscription Factor Binding and Induced Transcription Alter Chromosomal c-myc Replicator Activity | Full Text | References | PDF (482.4 KB)
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Article
Diminished S-Phase Cyclin-Dependent Kinase Function Elicits Vital Rad53-Dependent Checkpoint Responses in Saccharomyces cerevisiae
Daniel G. Gibson, Jennifer G. Aparicio, Fangfang Hu & Oscar M. Aparicio
Pages: 10208-10222
Published online: 27 Mar 2023
AbstractforDiminished S-Phase Cyclin-Dependent Kinase Function Elicits Vital Rad53-Dependent Checkpoint Responses in Saccharomyces cerevisiae | Full Text | References | PDF (673.7 KB)
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Article
Activation of the DNA Damage Checkpoint in Yeast Lacking the Histone Chaperone Anti-Silencing Function 1
Christopher Josh Ramey, Susan Howar, Melissa Adkins, Jeffrey Linger, Judson Spicer & Jessica K. Tyler
Pages: 10313-10327
Published online: 27 Mar 2023
AbstractforActivation of the DNA Damage Checkpoint in Yeast Lacking the Histone Chaperone Anti-Silencing Function 1 | Full Text | References | PDF (623.5 KB)
  • 34 Views
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Article
The Mouse Genomic Instability Mutation chaos1 Is an Allele of Polq That Exhibits Genetic Interaction with Atm
Naoko Shima, Robert J. Munroe & John C. Schimenti
Pages: 10381-10389
Published online: 27 Mar 2023
AbstractforThe Mouse Genomic Instability Mutation chaos1 Is an Allele of Polq That Exhibits Genetic Interaction with Atm | Full Text | References | PDF (448.1 KB)
  • 134 Views
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Article
Deficiency in SNM1 Abolishes an Early Mitotic Checkpoint Induced by Spindle Stress
Shamima Akhter, Christopher T. Richie, Jian Min Deng, Eric Brey, Xiaoshan Zhang, Charles Patrick Jr., Richard R. Behringer & Randy J. Legerski
Pages: 10448-10455
Published online: 27 Mar 2023
AbstractforDeficiency in SNM1 Abolishes an Early Mitotic Checkpoint Induced by Spindle Stress | Full Text | References | PDF (599 KB) | Supplemental
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Cell Growth and Development

Article
Stimulus-Coupled Spatial Restriction of Extracellular Signal-Regulated Kinase 1/2 Activity Contributes to the Specificity of Signal-Response Pathways
Angelique Whitehurst, Melanie H. Cobb & Michael A. White
Pages: 10145-10150
Published online: 27 Mar 2023
AbstractforStimulus-Coupled Spatial Restriction of Extracellular Signal-Regulated Kinase 1/2 Activity Contributes to the Specificity of Signal-Response Pathways | Full Text | References | PDF (452.8 KB)
  • 16 Views
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Article
Translational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2
Jing Deng, Phoebe D. Lu, Yuhong Zhang, Donalyn Scheuner, Randal J. Kaufman, Nahum Sonenberg, Heather P. Harding & David Ron
Pages: 10161-10168
Published online: 27 Mar 2023
AbstractforTranslational Repression Mediates Activation of Nuclear Factor Kappa B by Phosphorylated Translation Initiation Factor 2 | Full Text | References | PDF (360.6 KB)
  • 142 Views
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Article
G Protein-Coupled Receptor Kinase 5 Contains a DNA-Binding Nuclear Localization Sequence
Laura R. Johnson, Mark G. H. Scott & Julie A. Pitcher
Pages: 10169-10179
Published online: 27 Mar 2023
AbstractforG Protein-Coupled Receptor Kinase 5 Contains a DNA-Binding Nuclear Localization Sequence | Full Text | References | PDF (574.1 KB)
  • 42 Views
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Article
In Vivo Analysis of Importin α Proteins Reveals Cellular Proliferation Inhibition and Substrate Specificity
Christina Quensel, Beate Friedrich, Thomas Sommer, Enno Hartmann & Matthias Kohler
Pages: 10246-10255
Published online: 27 Mar 2023
AbstractforIn Vivo Analysis of Importin α Proteins Reveals Cellular Proliferation Inhibition and Substrate Specificity | Full Text | References | PDF (957.1 KB)
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Article
B-Cell Translocation Gene 2 (Btg2) Regulates Vertebral Patterning by Modulating Bone Morphogenetic Protein/Smad Signaling
Sean Park, Young Jae Lee, Ho-Jae Lee, Tsugio Seki, Kwon-Ho Hong, Joonil Park, Hideyuki Beppu, In Kyung Lim, Ji-Won Yoon, En Li, Seong-Jin Kim & S. Paul Oh
Pages: 10256-10262
Published online: 27 Mar 2023
AbstractforB-Cell Translocation Gene 2 (Btg2) Regulates Vertebral Patterning by Modulating Bone Morphogenetic Protein/Smad Signaling | Full Text | References | PDF (429.6 KB)
  • 28 Views
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Article
SWAP-70 Regulates c-kit-Induced Mast Cell Activation, Cell-Cell Adhesion, and Migration
Raja Rajeswari Sivalenka & Rolf Jessberger
Pages: 10277-10288
Published online: 27 Mar 2023
AbstractforSWAP-70 Regulates c-kit-Induced Mast Cell Activation, Cell-Cell Adhesion, and Migration | Full Text | References | PDF (784.2 KB)
  • 35 Views
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Article
Bcr-Abl-Mediated Protection from Apoptosis Downstream of Mitochondrial Cytochrome c Release
Paula B. Deming, Zachary T. Schafer, Jessica S. Tashker, Malia B. Potts, Mohanish Deshmukh & Sally Kornbluth
Pages: 10289-10299
Published online: 27 Mar 2023
AbstractforBcr-Abl-Mediated Protection from Apoptosis Downstream of Mitochondrial Cytochrome c Release | Full Text | References | PDF (422.8 KB)
  • 24 Views
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Article
Proapoptotic Function of the MET Tyrosine Kinase Receptor through Caspase Cleavage
David Tulasne, Julien Deheuninck, Filipe Calheiros Lourenço, Fabienne Lamballe, Zongling Ji, Catherine Leroy, Emilie Puchois, Anice Moumen, Flavio Maina, Patrick Mehlen & Véronique Fafeur
Pages: 10328-10339
Published online: 27 Mar 2023
AbstractforProapoptotic Function of the MET Tyrosine Kinase Receptor through Caspase Cleavage | Full Text | References | PDF (620.1 KB)
  • 11 Views
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Article
Ternary Complex Factor-Serum Response Factor Complex-Regulated Gene Activity Is Required for Cellular Proliferation and Inhibition of Apoptotic Cell Death
Elaine R. Vickers, Aneta Kasza, Isil Aksan Kurnaz, Anne Seifert, Leo A. H. Zeef, Amanda O'Donnell, Andy Hayes & Andrew D. Sharrocks
Pages: 10340-10351
Published online: 27 Mar 2023
AbstractforTernary Complex Factor-Serum Response Factor Complex-Regulated Gene Activity Is Required for Cellular Proliferation and Inhibition of Apoptotic Cell Death | Full Text | References | PDF (628.8 KB)
  • 31 Views
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Article
Sustained Activation of p38 Mitogen-Activated Protein Kinase and c-Jun N-Terminal Kinase Pathways by Hepatitis B Virus X Protein Mediates Apoptosis via Induction of Fas/FasL and Tumor Necrosis Factor (TNF) Receptor 1/TNF-α Expression
Wen-Horng Wang, Gérald Grégori, Ronald L. Hullinger & Ourania M. Andrisani
Pages: 10352-10365
Published online: 27 Mar 2023
AbstractforSustained Activation of p38 Mitogen-Activated Protein Kinase and c-Jun N-Terminal Kinase Pathways by Hepatitis B Virus X Protein Mediates Apoptosis via Induction of Fas/FasL and Tumor Necrosis Factor (TNF) Receptor 1/TNF-α Expression | Full Text | References | PDF (1,015 KB)
  • 17 Views
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Article
p53 Stabilization and Accumulation Induced by Human Vaccinia-Related Kinase 1
Francisco M. Vega, Ana Sevilla & Pedro A. Lazo
Pages: 10366-10380
Published online: 27 Mar 2023
Abstractforp53 Stabilization and Accumulation Induced by Human Vaccinia-Related Kinase 1 | Full Text | References | PDF (1 MB)
  • 54 Views
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Article
An Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling
Manuel Ascano Jr. & David J. Robbins
Pages: 10397-10405
Published online: 27 Mar 2023
AbstractforAn Intramolecular Association between Two Domains of the Protein Kinase Fused Is Necessary for Hedgehog Signaling | Full Text | References | PDF (576.5 KB)
  • 12 Views
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Article
Genetic Interaction between Rb and K-ras in the Control of Differentiation and Tumor Suppression
Chiaki Takahashi, Bernardo Contreras, Roderick T. Bronson, Massimo Loda & Mark E. Ewen
Pages: 10406-10415
Published online: 27 Mar 2023
AbstractforGenetic Interaction between Rb and K-ras in the Control of Differentiation and Tumor Suppression | Full Text | References | PDF (750.4 KB)
  • 11 Views
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Article
Partial Cleavage of RasGAP by Caspases Is Required for Cell Survival in Mild Stress Conditions
Jiang-Yan Yang, David Michod, Joël Walicki, Brona M. Murphy, Shailaja Kasibhatla, Seamus J. Martin & Christian Widmann
Pages: 10425-10436
Published online: 27 Mar 2023
AbstractforPartial Cleavage of RasGAP by Caspases Is Required for Cell Survival in Mild Stress Conditions | Full Text | References | PDF (817.1 KB) | Supplemental
  • 22 Views
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Article
A Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity
Diego Sbrissa, Ognian C. Ikonomov, Jana Strakova, Rajeswari Dondapati, Krzysztof Mlak, Robert Deeb, Robert Silver & Assia Shisheva
Pages: 10437-10447
Published online: 27 Mar 2023
AbstractforA Mammalian Ortholog of Saccharomyces cerevisiae Vac14 That Associates with and Up-Regulates PIKfyve Phosphoinositide 5-Kinase Activity | Full Text | References | PDF (867.6 KB) | Supplemental
  • 30 Views
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Article
Binding to Nonmethylated CpG DNA Is Essential for Target Recognition, Transactivation, and Myeloid Transformation by an MLL Oncoprotein
Paul M. Ayton, Everett H. Chen & Michael L. Cleary
Pages: 10470-10478
Published online: 27 Mar 2023
AbstractforBinding to Nonmethylated CpG DNA Is Essential for Target Recognition, Transactivation, and Myeloid Transformation by an MLL Oncoprotein | Full Text | References | PDF (424 KB)
  • 19 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Disruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis
Francesco Piazza, José A. Costoya, Taha Merghoub, Robin M. Hobbs & Pier Paolo Pandolfi
Pages: 10456-10469
Published online: 27 Mar 2023
AbstractforDisruption of PLZP in Mice Leads to Increased T-Lymphocyte Proliferation, Cytokine Production, and Altered Hematopoietic Stem Cell Homeostasis | Full Text | References | PDF (971.5 KB)
  • 25 Views
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