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Cell Growth and Development

Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence

Jennifer A. Benanti1 Program in Cancer Biology, Fred Hutchinson Cancer Research Center;2 Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington98109-1024
&
Denise A. Galloway1 Program in Cancer Biology, Fred Hutchinson Cancer Research CenterCorrespondence[email protected]
Pages 2842-2852 | Received 23 Oct 2003, Accepted 05 Jan 2004, Published online: 27 Mar 2023

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Fan Zhang, Siti Mariam Zakaria, Vedrana Högqvist Tabor, Madhurendra Singh, Susanna Tronnersjö, Jacob Goodwin, Galina Selivanova, Jiri Bartek, Alina Castell & Lars-Gunnar Larsson. (2018) MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. Cell Cycle 17:24, pages 2697-2715.
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Xiaoming Sun, Aizhan Bizhanova, Timothy D. Matheson, Jun Yu, Lihua Julie Zhu & Paul D. Kaufman. (2017) Ki-67 Contributes to Normal Cell Cycle Progression and Inactive X Heterochromatin in p21 Checkpoint-Proficient Human Cells. Molecular and Cellular Biology 37:17.
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Anna Bianchi-Smiraglia & Mikhail A. Nikiforov. (2012) Controversial aspects of oncogene-induced senescence. Cell Cycle 11:22, pages 4147-4151.
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Myra L. Wang, Ryan Walsh, Kristin L. Robinson, Julja Burchard, Steven R. Bartz, Michele Cleary, Denise A. Galloway & Carla Grandori. (2011) Gene expression signature of c-MYC-immortalized human fibroblasts reveals loss of growth inhibitory response to TGFβ. Cell Cycle 10:15, pages 2540-2548.
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João F. Passos & Thomas Von Zglinicki. (2006) Oxygen free radicals in cell senescence: Are they signal transducers?. Free Radical Research 40:12, pages 1277-1283.
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Jesse S. Boehm, Meghan T. Hession, Sara E. Bulmer & William C. Hahn. (2005) Transformation of Human and Murine Fibroblasts without Viral Oncoproteins. Molecular and Cellular Biology 25:15, pages 6464-6474.
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