Molecular and Cellular Biology, Volume 24, Issue 7 (2004)

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Molecular and Cellular Biology, Volume 24, Issue 7 (2004)

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Gene Expression

Article
Molecular Mechanism of Suppression of Testicular Steroidogenesis by Proinflammatory Cytokine Tumor Necrosis Factor Alpha
Cheol Yi Hong, Jin Hee Park, Ryun Seop Ahn, Suhn Young Im, Hueng-Sik Choi, Jaemog Soh, Synthia H. Mellon & Keesook Lee
Pages: 2593-2604
Published online: 27 Mar 2023
AbstractforMolecular Mechanism of Suppression of Testicular Steroidogenesis by Proinflammatory Cytokine Tumor Necrosis Factor Alpha | Full Text | References | PDF (435.6 KB)
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Article
Identification of Staufen in the Human Immunodeficiency Virus Type 1 Gag Ribonucleoprotein Complex and a Role in Generating Infectious Viral Particles
Laurent Chatel-Chaix, Jean-Francois Clément, Catherine Martel, Véronique Bériault, Anne Gatignol, Luc DesGroseillers & Andrew J. Mouland
Pages: 2637-2648
Published online: 27 Mar 2023
AbstractforIdentification of Staufen in the Human Immunodeficiency Virus Type 1 Gag Ribonucleoprotein Complex and a Role in Generating Infectious Viral Particles | Full Text | References | PDF (528.2 KB)
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Article
snRNAs Contain Specific SMN-Binding Domains That Are Essential for snRNP Assembly
Jeongsik Yong, Tracey J. Golembe, Daniel J. Battle, Livio Pellizzoni & Gideon Dreyfuss
Pages: 2747-2756
Published online: 27 Mar 2023
AbstractforsnRNAs Contain Specific SMN-Binding Domains That Are Essential for snRNP Assembly | Full Text | References | PDF (494.2 KB)
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Article
Secondary Structure as a Functional Feature in the Downstream Region of Mammalian Polyadenylation Signals
Chunxiao Wu & James C. Alwine
Pages: 2789-2796
Published online: 27 Mar 2023
AbstractforSecondary Structure as a Functional Feature in the Downstream Region of Mammalian Polyadenylation Signals | Full Text | References | PDF (628.6 KB)
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Article
A Nonconserved Surface of the TFIIB Zinc Ribbon Domain Plays a Direct Role in RNA Polymerase II Recruitment
Thomas C. Tubon, William P. Tansey & Winship Herr
Pages: 2863-2874
Published online: 27 Mar 2023
AbstractforA Nonconserved Surface of the TFIIB Zinc Ribbon Domain Plays a Direct Role in RNA Polymerase II Recruitment | Full Text | References | PDF (530.9 KB)
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Article
The Essential WD Repeat Protein Swd2 Has Dual Functions in RNA Polymerase II Transcription Termination and Lysine 4 Methylation of Histone H3
Hailing Cheng, Xiaoyuan He & Claire Moore
Pages: 2932-2943
Published online: 27 Mar 2023
AbstractforThe Essential WD Repeat Protein Swd2 Has Dual Functions in RNA Polymerase II Transcription Termination and Lysine 4 Methylation of Histone H3 | Full Text | References | PDF (575 KB)
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Article
Loss of Translational Control in Yeast Compromised for the Major mRNA Decay Pathway
L. E. A. Holmes, S. G. Campbell, S. K. De Long, A. B. Sachs & M. P. Ashe
Pages: 2998-3010
Published online: 27 Mar 2023
AbstractforLoss of Translational Control in Yeast Compromised for the Major mRNA Decay Pathway | Full Text | References | PDF (467 KB)
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Transcriptional Regulation

Article
Histone Fold Protein Dls1p Is Required for Isw2-Dependent Chromatin Remodeling In Vivo
Audrey D. McConnell, Marnie E. Gelbart & Toshio Tsukiyama
Pages: 2605-2613
Published online: 27 Mar 2023
AbstractforHistone Fold Protein Dls1p Is Required for Isw2-Dependent Chromatin Remodeling In Vivo | Full Text | References | PDF (319.4 KB)
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Article
Forkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators
Michael L. Major, Rita Lepe & Robert H. Costa
Pages: 2649-2661
Published online: 27 Mar 2023
AbstractforForkhead Box M1B Transcriptional Activity Requires Binding of Cdk-Cyclin Complexes for Phosphorylation-Dependent Recruitment of p300/CBP Coactivators | Full Text | References | PDF (628.9 KB)
  • 71 Views
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Article
Basic Helix-Loop-Helix Proteins Bind to TrkB and p21Cip1 Promoters Linking Differentiation and Cell Cycle Arrest in Neuroblastoma Cells
Yuhui Liu, Mario Encinas, Joan X. Comella, Martí Aldea & Carme Gallego
Pages: 2662-2672
Published online: 27 Mar 2023
AbstractforBasic Helix-Loop-Helix Proteins Bind to TrkB and p21Cip1 Promoters Linking Differentiation and Cell Cycle Arrest in Neuroblastoma Cells | Full Text | References | PDF (502.9 KB)
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Article
Rapid Glucocorticoid Receptor Exchange at a Promoter Is Coupled to Transcription and Regulated by Chaperones and Proteasomes
Diana A. Stavreva, Waltraud G. Müller, Gordon L. Hager, Carolyn L. Smith & James G. McNally
Pages: 2682-2697
Published online: 27 Mar 2023
AbstractforRapid Glucocorticoid Receptor Exchange at a Promoter Is Coupled to Transcription and Regulated by Chaperones and Proteasomes | Full Text | References | PDF (2 MB)
  • 58 Views
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Article
Functional Analysis of the Mad1-mSin3A Repressor-Corepressor Interaction Reveals Determinants of Specificity, Affinity, and Transcriptional Response
Shaun M. Cowley, Richard S. Kang, John V. Frangioni, Jason J. Yada, Alec M. DeGrand, Ishwar Radhakrishnan & Robert N. Eisenman
Pages: 2698-2709
Published online: 27 Mar 2023
AbstractforFunctional Analysis of the Mad1-mSin3A Repressor-Corepressor Interaction Reveals Determinants of Specificity, Affinity, and Transcriptional Response | Full Text | References | PDF (498.4 KB)
  • 25 Views
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Article
Meox Homeodomain Proteins Are Required for Bapx1 Expression in the Sclerotome and Activate Its Transcription by Direct Binding to Its Promoter
Isabel Rodrigo, Paola Bovolenta, Baljinder S. Mankoo & Kenji Imai
Pages: 2757-2766
Published online: 27 Mar 2023
AbstractforMeox Homeodomain Proteins Are Required for Bapx1 Expression in the Sclerotome and Activate Its Transcription by Direct Binding to Its Promoter | Full Text | References | PDF (483.6 KB)
  • 26 Views
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Article
Phosphorylation Controls Ikaros's Ability To Negatively Regulate the G1-S Transition
Pablo Gómez-del Arco, Kazushige Maki & Katia Georgopoulos
Pages: 2797-2807
Published online: 27 Mar 2023
AbstractforPhosphorylation Controls Ikaros's Ability To Negatively Regulate the G1-S Transition | Full Text | References | PDF (554.3 KB)
  • 34 Views
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Article
Brn-2 Expression Controls Melanoma Proliferation and Is Directly Regulated by β-Catenin
Jane Goodall, Silvia Martinozzi, Timothy J. Dexter, Delphine Champeval, Suzanne Carreira, Lionel Larue & Colin R. Goding
Pages: 2915-2922
Published online: 27 Mar 2023
AbstractforBrn-2 Expression Controls Melanoma Proliferation and Is Directly Regulated by β-Catenin | Full Text | References | PDF (255.5 KB)
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Article
The Brn-2 Transcription Factor Links Activated BRAF to Melanoma Proliferation
Jane Goodall, Claudia Wellbrock, Timothy J. Dexter, Karen Roberts, Richard Marais & Colin R. Goding
Pages: 2923-2931
Published online: 27 Mar 2023
AbstractforThe Brn-2 Transcription Factor Links Activated BRAF to Melanoma Proliferation | Full Text | References | PDF (288.4 KB)
  • 24 Views
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Article
A Novel Complex Regulates cardiac actin Gene Expression through Interaction of Emb, a Class VI POU Domain Protein, MEF2D, and the Histone Transacetylase p300
S. Molinari, F. Relaix, M. Lemonnier, B. Kirschbaum, B. Schäfer & M. Buckingham
Pages: 2944-2957
Published online: 27 Mar 2023
AbstractforA Novel Complex Regulates cardiac actin Gene Expression through Interaction of Emb, a Class VI POU Domain Protein, MEF2D, and the Histone Transacetylase p300 | Full Text | References | PDF (521 KB)
  • 12 Views
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Article
HBP1 Repression of the p47phox Gene: Cell Cycle Regulation via the NADPH Oxidase
Stephen P. Berasi, Mei Xiu, Amy S. Yee & K. Eric Paulson
Pages: 3011-3024
Published online: 27 Mar 2023
AbstractforHBP1 Repression of the p47phox Gene: Cell Cycle Regulation via the NADPH Oxidase | Full Text | References | PDF (403.1 KB)
  • 12 Views
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Article
Chromatin-Mediated Restriction of Nuclear Factor 1/CTF Binding in a Repressed and Hormone-Activated Promoter In Vivo
Sergey Belikov, Carolina Åstrand, Per-Henrik Holmqvist & Örjan Wrange
Pages: 3036-3047
Published online: 27 Mar 2023
AbstractforChromatin-Mediated Restriction of Nuclear Factor 1/CTF Binding in a Repressed and Hormone-Activated Promoter In Vivo | Full Text | References | PDF (608.7 KB)
  • 8 Views
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Cell Growth and Development

Article
Protein Kinase Cδ Selectively Regulates Protein Kinase D-Dependent Activation of NF-κB in Oxidative Stress Signaling
Peter Storz, Heike Döppler & Alex Toker
Pages: 2614-2626
Published online: 27 Mar 2023
AbstractforProtein Kinase Cδ Selectively Regulates Protein Kinase D-Dependent Activation of NF-κB in Oxidative Stress Signaling | Full Text | References | PDF (600.2 KB)
  • 53 Views
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Article
N-Terminal Fragment of c-FLIP(L) Processed by Caspase 8 Specifically Interacts with TRAF2 and Induces Activation of the NF-κB Signaling Pathway
Takao Kataoka & Jürg Tschopp
Pages: 2627-2636
Published online: 27 Mar 2023
AbstractforN-Terminal Fragment of c-FLIP(L) Processed by Caspase 8 Specifically Interacts with TRAF2 and Induces Activation of the NF-κB Signaling Pathway | Full Text | References | PDF (405.9 KB)
  • 32 Views
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Article
Inhibition of Mist1 Homodimer Formation Induces Pancreatic Acinar-to-Ductal Metaplasia
Liqin Zhu, Thai Tran, J. Michael Rukstalis, Peichuan Sun, Barbara Damsz & Stephen F. Konieczny
Pages: 2673-2681
Published online: 27 Mar 2023
AbstractforInhibition of Mist1 Homodimer Formation Induces Pancreatic Acinar-to-Ductal Metaplasia | Full Text | References | PDF (1.1 MB)
  • 55 Views
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Article
ATP-Sensitive K+ Channels Regulate the Concentrative Adenosine Transporter CNT2 following Activation by A1 Adenosine Receptors
Sylvie Duflot, Bárbara Riera, Sonia Fernández-Veledo, Vicent Casadó, Robert I. Norman, F. Javier Casado, Carme Lluís, Rafael Franco & Marçal Pastor-Anglada
Pages: 2710-2719
Published online: 27 Mar 2023
AbstractforATP-Sensitive K+ Channels Regulate the Concentrative Adenosine Transporter CNT2 following Activation by A1 Adenosine Receptors | Full Text | References | PDF (589.4 KB)
  • 17 Views
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Article
Securin Is a Target of the UV Response Pathway in Mammalian Cells
Francisco Romero, Ana M. Gil-Bernabé, Carmen Sáez, Miguel A. Japón, José A. Pintor-Toro & María Tortolero
Pages: 2720-2733
Published online: 27 Mar 2023
AbstractforSecurin Is a Target of the UV Response Pathway in Mammalian Cells | Full Text | References | PDF (646.8 KB)
  • 6 Views
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Article
The Yeast Split-Ubiquitin Membrane Protein Two-Hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-Associated Protein Tyrosine Phosphatase-Like B
Bing Wang, Jerry Pelletier, Michel J. Massaad, Annette Herscovics & Gordon C. Shore
Pages: 2767-2778
Published online: 27 Mar 2023
AbstractforThe Yeast Split-Ubiquitin Membrane Protein Two-Hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-Associated Protein Tyrosine Phosphatase-Like B | Full Text | References | PDF (661.1 KB)
  • 26 Views
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Article
Cellular Senescence Requires CDK5 Repression of Rac1 Activity
Kamilah Alexander, Hai-Su Yang & Philip W. Hinds
Pages: 2808-2819
Published online: 27 Mar 2023
AbstractforCellular Senescence Requires CDK5 Repression of Rac1 Activity | Full Text | References | PDF (710.6 KB)
  • 37 Views
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Article
ΔFosB Induces Osteosclerosis and Decreases Adipogenesis by Two Independent Cell-Autonomous Mechanisms
Marie Kveiborg, George Sabatakos, Riccardo Chiusaroli, Meilin Wu, William M. Philbrick, William C. Horne & Roland Baron
Pages: 2820-2830
Published online: 27 Mar 2023
AbstractforΔFosB Induces Osteosclerosis and Decreases Adipogenesis by Two Independent Cell-Autonomous Mechanisms | Full Text | References | PDF (688 KB)
  • 30 Views
  • 57 CrossRef citations
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Article
Overexpression of Inducible Cyclic AMP Early Repressor Inhibits Transactivation of Genes and Cell Proliferation in Pancreatic β Cells
Akari Inada, Yoshiyuki Hamamoto, Yoshiyuki Tsuura, Jun-ichi Miyazaki, Shinya Toyokuni, Yu Ihara, Koichiro Nagai, Yuichiro Yamada, Susan Bonner-Weir & Yutaka Seino
Pages: 2831-2841
Published online: 27 Mar 2023
AbstractforOverexpression of Inducible Cyclic AMP Early Repressor Inhibits Transactivation of Genes and Cell Proliferation in Pancreatic β Cells | Full Text | References | PDF (699.3 KB)
  • 19 Views
  • 63 CrossRef citations
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Article
Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence
Jennifer A. Benanti & Denise A. Galloway
Pages: 2842-2852
Published online: 27 Mar 2023
AbstractforNormal Human Fibroblasts Are Resistant to RAS-Induced Senescence | Full Text | References | PDF (2.5 MB)
  • 130 Views
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Article
Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance
Janine T. Erler, Christopher J. Cawthorne, Kaye J. Williams, Marianne Koritzinsky, Bradley G. Wouters, Clare Wilson, Crispin Miller, Costas Demonacos, Ian J. Stratford & Caroline Dive
Pages: 2875-2889
Published online: 27 Mar 2023
AbstractforHypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance | Full Text | References | PDF (966.5 KB)
  • 92 Views
  • 299 CrossRef citations
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Article
Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells
Carsten Müller-Tidow, Björn Steffen, Thomas Cauvet, Lara Tickenbrock, Ping Ji, Sven Diederichs, Bülent Sargin, Gabriele Köhler, Matthias Stelljes, Elena Puccetti, Martin Ruthardt, Sven deVos, Scott W. Hiebert, H. Phillip Koeffler, Wolfgang E. Berdel & Hubert Serve
Pages: 2890-2904
Published online: 27 Mar 2023
AbstractforTranslocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells | Full Text | References | PDF (994.7 KB)
  • 79 Views
  • 224 CrossRef citations
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Article
Growth Factor-Mediated Induction of HDM2 Positively Regulates Hypoxia-Inducible Factor 1α Expression
Julia I. Bárdos, Noan-Minh Chau & Margaret Ashcroft
Pages: 2905-2914
Published online: 27 Mar 2023
AbstractforGrowth Factor-Mediated Induction of HDM2 Positively Regulates Hypoxia-Inducible Factor 1α Expression | Full Text | References | PDF (387.2 KB)
  • 12 Views
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Article
A Novel mTOR-Regulated Phosphorylation Site in Elongation Factor 2 Kinase Modulates the Activity of the Kinase and Its Binding to Calmodulin
Gareth J. Browne & Christopher G. Proud
Pages: 2986-2997
Published online: 27 Mar 2023
AbstractforA Novel mTOR-Regulated Phosphorylation Site in Elongation Factor 2 Kinase Modulates the Activity of the Kinase and Its Binding to Calmodulin | Full Text | References | PDF (518 KB)
  • 63 Views
  • 201 CrossRef citations
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Article
Ribosomal S6 Kinase (RSK) Regulates Phosphorylation of Filamin A on an Important Regulatory Site
Michele S. Woo, Yasutaka Ohta, Isaac Rabinovitz, Thomas P. Stossel & John Blenis
Pages: 3025-3035
Published online: 27 Mar 2023
AbstractforRibosomal S6 Kinase (RSK) Regulates Phosphorylation of Filamin A on an Important Regulatory Site | Full Text | References | PDF (525.9 KB)
  • 54 Views
  • 132 CrossRef citations
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Article
Inhibition of NF-κB Activity by IκBβ in Association with κB-Ras
Yi Chen, Sebastien Vallee, Joann Wu, Don Vu, John Sondek & Gourisankar Ghosh
Pages: 3048-3056
Published online: 27 Mar 2023
AbstractforInhibition of NF-κB Activity by IκBβ in Association with κB-Ras | Full Text | References | PDF (382 KB)
  • 24 Views
  • 40 CrossRef citations
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Article
p38 Mitogen-Activated Protein Kinase Is the Central Regulator of Cyclic AMP-Dependent Transcription of the Brown Fat Uncoupling Protein 1 Gene
Wenhong Cao, Kiefer W. Daniel, Jacques Robidoux, Pere Puigserver, Alexander V. Medvedev, Xu Bai, Lisa M. Floering, Bruce M. Spiegelman & Sheila Collins
Pages: 3057-3067
Published online: 27 Mar 2023
Abstractforp38 Mitogen-Activated Protein Kinase Is the Central Regulator of Cyclic AMP-Dependent Transcription of the Brown Fat Uncoupling Protein 1 Gene | Full Text | References | PDF (446.1 KB)
  • 191 Views
  • 422 CrossRef citations
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Dna Dynamics and Chromosome Structure

Article
Palm Mutants in DNA Polymerases α and η Alter DNA Replication Fidelity and Translesion Activity
Atsuko Niimi, Siripan Limsirichaikul, Shonen Yoshida, Shigenori Iwai, Chikahide Masutani, Fumio Hanaoka, Eric T. Kool, Yukihiro Nishiyama & Motoshi Suzuki
Pages: 2734-2746
Published online: 27 Mar 2023
AbstractforPalm Mutants in DNA Polymerases α and η Alter DNA Replication Fidelity and Translesion Activity | Full Text | References | PDF (770.2 KB)
  • 26 Views
  • 73 CrossRef citations
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Article
Mdt1, a Novel Rad53 FHA1 Domain-Interacting Protein, Modulates DNA Damage Tolerance and G2/M Cell Cycle Progression in Saccharomycescerevisiae
Brietta L. Pike, Suganya Yongkiettrakul, Ming-Daw Tsai & Jörg Heierhorst
Pages: 2779-2788
Published online: 27 Mar 2023
AbstractforMdt1, a Novel Rad53 FHA1 Domain-Interacting Protein, Modulates DNA Damage Tolerance and G2/M Cell Cycle Progression in Saccharomycescerevisiae | Full Text | References | PDF (640.6 KB)
  • 9 Views
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Article
Silencing of Chromatin Assembly Factor 1 in Human Cells Leads to Cell Death and Loss of Chromatin Assembly during DNA Synthesis
Arman Nabatiyan & Torsten Krude
Pages: 2853-2862
Published online: 27 Mar 2023
AbstractforSilencing of Chromatin Assembly Factor 1 in Human Cells Leads to Cell Death and Loss of Chromatin Assembly during DNA Synthesis | Full Text | References | PDF (640.8 KB)
  • 30 Views
  • 93 CrossRef citations
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Article
Modular Structure of the Human Lamin B2 Replicator
Sónia Paixão, Ivan N. Colaluca, Matthieu Cubells, Fiorenzo A. Peverali, Annarita Destro, Sara Giadrossi, Mauro Giacca, Arturo Falaschi, Silvano Riva & Giuseppe Biamonti
Pages: 2958-2967
Published online: 27 Mar 2023
AbstractforModular Structure of the Human Lamin B2 Replicator | Full Text | References | PDF (372.7 KB)
  • 16 Views
  • 69 CrossRef citations
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Article
Apoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2
Harry A. Rogoff, Mary T. Pickering, Fiona M. Frame, Michelle E. Debatis, Yolanda Sanchez, Stephen Jones & Timothy F. Kowalik
Pages: 2968-2977
Published online: 27 Mar 2023
AbstractforApoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2 | Full Text | References | PDF (360.9 KB)
  • 17 Views
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Mammalian Genetic Models With Minimal Or Complex Phenotypes

Article
Obesity and Endocrine Dysfunction in Mice with Deletions of both Neuropeptide Y and Galanin
J. G. Hohmann, D. N. Teklemichael, D. Weinshenker, D. Wynick, D. K. Clifton & R. A. Steiner
Pages: 2978-2985
Published online: 27 Mar 2023
AbstractforObesity and Endocrine Dysfunction in Mice with Deletions of both Neuropeptide Y and Galanin | Full Text | References | PDF (229.5 KB)
  • 22 Views
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Errata

Correction
Human RNPS1 and Its Associated Factors: a Versatile Alternative Pre-mRNA Splicing Regulator In Vivo
Page: 3068
Published online: 27 Mar 2023
CitationforHuman RNPS1 and Its Associated Factors: a Versatile Alternative Pre-mRNA Splicing Regulator In Vivo | Full Text | PDF (17.3 KB)
  • 101 Views
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